A Large Area Real-Time Imaging System for Screening DNA Libraries

Information

• NSF Award
• 9201872

Owner

• RADIATION MONITORING DEVICES, INC.

• Award Id

  9201872

• Award Effective Date

  1/1/1993 - 31 years ago

• Award Expiration Date

  6/30/1995 - 28 years ago

• Award Amount

  $ 250,000.00

• Award Instrument

  Standard Grant

This is a SBIR Phase II project. The objective of this research is to develop an imaging system for screening DNA libraries. Genome research is one of the most active research areas in biology today, and an improved way to analyze DNA libraries will be useful. The research plan is to utilize a new nuclear detector to generate a real time image of the distribution of radioactivity on the transfer membrane containing DNA samples. The image will be directly projected onto the primary agar plate. In the Phase I project, a new large area imaging instrument prototype has been developed using two orthogonal arrays of scintillating fibers, each coupled to a position-sensitive photomultiplier tube. In the Phase II project, research will focus on improving the performance of the prototype and designing the ways of increasing area. If successful, the new device will improve the efficiency and precision of the identification and isolation of genes.

• Program Officer

  Ritchie B. Coryell

• Min Amd Letter Date

  1/7/1993 - 31 years ago

• Max Amd Letter Date

  6/30/1997 - 26 years ago

• ARRA Amount

• Name

  Radiation Monitoring Devices Inc

• City

  Watertown

• State

  MA

• Country

  United States

• Address

  44 Hunt Street

• Postal Code

  024724699

• Phone Number

  6176686801

• First Name

  Gerald

• Last Name

  Entine

• Email Address

  GEntine@rmdinc.com

• Start Date

  1/1/1993 12:00:00 AM

• Name

  Life Science Biological

• Code

  61