The present disclosure generally relates to a medicament delivery device configured to expel medicament from a medicament container.
A number of medical conditions require reliable provision of a medicament from a medicament delivery device. The medicament is typically comprised in a medicament container within the medicament delivery device, the medicament container being configured to expel the medicament via some type of delivery member, such as a needle or a nozzle.
These days, a number of different medicament delivery devices exist, including various types of injectors (for example pen injectors, autoinjectors, on-body devices). Although many of these devices have enabled major improvements in the management of a number of medical conditions, various drawbacks do still exist in the current technology.
According to an example, the medicament delivery device often comprises a needle cover protruding out from a housing and is arranged to cover an injections needle before usage. When pressing the medicament delivery device, and in particular the needle cover, onto e.g. the skin of a medicament recipient, the needle cover is pushed into housing of the medicament delivery device. The needle cover is still arranged in abutment with the skin of the medicament recipient. Thereafter, the needle is protracted out from the needle cover and inserted through the skin of the medicament recipient by actuation of the medicament delivery device, whereafter the medicament is subsequently delivered through the injection needle into the medicament recipient. However, due to the mechanical interaction between the components of the medicament delivery device, the needle cover sometimes moves slightly out from the housing when actuating the medicament delivery device. The needle cover may hereby generate an unpleasant kick back force on the skin of the medicament recipient. The kick back force may be generated by the motion of a so-called syringe collar interacting with the needle cover. The kick back force may also be generated by a proximal end portion of a plunger rod forcing medicament out of the medicament container.
Medicament delivery devices are thus in need of further improvement, in particular when it comes to comfort for the users of medicament delivery devices.
The invention is defined by the appended claims, to which reference should now be made. An object of the present disclosure is thus to provide a medicament delivery device which solves, or at least mitigates, problems of the prior art.
In the present disclosure, when the term “distal direction” is used, this refers to the direction pointing away from the dose delivery site during use of the medicament delivery device. When the term “distal part/end” is used, this refers to the part/end of the delivery device, or the parts/ends of the members thereof, which under use of the medicament delivery device is/are located furthest away from the dose delivery site. Correspondingly, when the term “proximal direction” is used, this refers to the direction pointing towards the dose delivery site during use of the medicament delivery device. When the term “proximal part/end” is used, this refers to the part/end of the delivery device, or the parts/ends of the members thereof, which under use of the medicament delivery device is/are located closest to the dose delivery site.
Further, the term “longitudinal”, “longitudinally”, “axially” or “axial” refer to a direction extending from the proximal end to the distal end, typically along the device or components thereof in the direction of the longest extension of the device and/or component.
Similarly, the terms “transverse”, “transversal” and “transversally” refer to a direction generally perpendicular to the longitudinal direction.
Further, the terms “circumference”, “circumferential”, or “circumferentially” refer to a circumference or a circumferential direction relative to an axis, typically a central axis extending in the direction of the longest extension of the device and/or component. Similarly, “radial” or “radially” refer to a direction extending radially relative to the axis, and “rotation”, “rotational” and “rotationally” refer to rotation relative to the axis.
According to a first aspect of the present disclosure there is provided a medicament delivery device configured to expel a medicament from a medicament container comprising an injection needle, the medicament delivery device comprising a housing, a medicament delivery member having a tubular body extending along an axis in an axial direction from a proximal end to a distal end, the medicament delivery member comprises an opening configured to receive the medicament container, wherein the medicament delivery member is axially movable within the housing, a syringe collar at least partly enclosed by the medicament delivery member, wherein the medicament delivery member and the syringe collar are axially movable within the housing relative to each other, and a medicament delivery member spring arranged between, and in contact with, the medicament delivery member and the syringe collar, wherein the medicament delivery device is configured to assume a retracted state in which the injection needle is arranged inside the medicament delivery member and prevented from external exposure, and a protracted state in which the injection needle is configured to protrude proximally from the proximal end of the medicament delivery member, wherein, when the medicament delivery device transition from the retracted state to the protracted state, the medicament delivery member is arranged stationary relative to the housing and the syringe collar is arranged to move relative to the medicament delivery member in a proximal direction and compress the medicament delivery member spring against the medicament delivery member, and wherein the syringe collar is axially locked to a surface portion of the housing when the medicament delivery device assumes the protracted state such that an axial force from the syringe collar, generated during the transition from the retracted state to the protracted state, is absorbed by the surface portion of the housing.
The wording medicament delivery member should be construed as a member arranged to prevent exposure of a needle. Thus, before and after usage of the medicament delivery device, the medicament delivery member prevents a user of the medicament delivery device to accidentally be stung by the needle. The medicament delivery member may also be referred to as a needle cover.
Further, the definition “syringe collar is axially locked to a surface portion of the housing” should be construed as the syringe collar is directly locked to the surface portion of the housing as well as that the syringe collar is indirectly locked to the surface portion of the housing via another member of the medicament delivery device. The syringe collar may thus be arranged in mechanical contact with the surface portion of the housing when the syringe collar is axially locked to the surface portion. The syringe collar may alternatively be connected to the surface portion of the housing via e.g. a rotator of the medicament delivery device.
The present invention is based on the insight that by arranging the medicament delivery member stationary relative to the housing as well as to axially lock the syringe collar axially to the surface portion of the housing, the kick back force is not directed into the skin medicament recipient, but instead absorbed by the housing. Hereby, the user of the medicament delivery device will feel a slight kick back force in his/her hand, which is less unpleasant compared to absorbing the kick back force by the skin in the vicinity of the inserted needle.
According to an example embodiment, the medicament delivery device may further comprise a rotator having a distal end and a proximal end, wherein the rotator is arranged within a portion of the housing.
According to an example embodiment, the medicament delivery member may comprise a protrusion at the distal end of the medicament delivery member, the protrusion being arranged in a first axially extending track of the rotator, wherein the protrusion and a distal end portion of the first axially extending track of the rotator are arranged at a distance from each other when the medicament delivery device assumes the protracted state.
When the medicament delivery member is pressed against e.g. the skin of the medicament recipient, the medicament delivery member is moved distally relative to the rotator, and the protrusion of the medicament delivery member is pressed against an inclined surface of the first axially extending track. Due to the interaction between the protrusion and the inclined surface of the first axially extending track, the rotator will rotate simultaneously as the protrusion moves distally. By arranging the protrusion and the distal end portion of the first axially extending track at a distance from each other when the medicament assumes the protracted state, no force will be transmitted between the rotator and the medicament delivery member, thus preventing the kick back force to be absorbed by the skin of the medicament recipient.
According to an example embodiment, the syringe collar may comprise a radially extending protrusion.
According to an example embodiment, the radially extending protrusion of the syringe collar may be arranged in abutment with a proximal end portion of an axially extending track of the portion of the housing when the medicament delivery device assumes the protracted state. When the medicament delivery device transitions from the retracted state to the protracted state, the movement of the syringe collar will be stopped by the interaction between the radially extending protrusion of the syringe collar and the proximal end portion of the axially extending track of the portion of the housing, whereby the kick back force will be absorbed by the housing portion at the proximal end portion of the axially extending track of the portion of the housing.
Accordingly, and according to an example embodiment, the radially extending protrusion of the syringe collar is arranged in the axially extending track of the portion of the housing and axially movable along the axially extending track during the transition from the retracted state to the protracted state.
According to an example embodiment, the housing may comprise a first housing portion and a second housing portion arranged in contact with each other, the first housing portion being arranged to at least partly house the medicament delivery member, and the second housing portion is arranged distally from the first housing portion and configured to be held by the hand of a user. Furthermore, and according to an example embodiment, the surface portion of the housing may be arranged on the first housing portion. Since the first and second housing portions are arranged in contact with each other, i.e. they are in axial abutment with each other, the kick back force will be transmitted into the first housing portion and absorbed by the user's hand holding the second housing portion.
According to an example embodiment, the rotator may comprise a second axially extending track, the second axially extending track comprising an inclined surface portion, wherein the radially extending protrusion of the syringe collar is arranged in the second axially extending track and arranged to follow the inclined surface portion when the medicament delivery device transitions from the retracted state to the protracted state.
According to an example embodiment, the radially extending protrusion of the syringe collar may be arranged in abutment with the inclined surface portion of the rotator when the syringe collar follows the inclined surface portion, thereby forcing the rotator to be moved in a proximal direction and to rotate around an axially extending geometric center axis of the medicament delivery device.
According to an example embodiment, the radially extending protrusion of the syringe collar may be arranged in abutment with a proximal end portion of the second axially extending track when the medicament delivery device assumes the protracted state. When the medicament delivery device transitions from the retracted state to the protracted state, and the radially extending protrusion of the syringe collar finally is arranged in abutment with the proximal end portion of the second axially extending track, the force from the motion of the syringe collar is absorbed by the rotator. As described above, the protrusion of the medicament delivery member may be arranged at a distance from the distal end portion of the first axially extending track of the rotator. The force generated from the motion of the syringe collar will thus not be absorbed by the medicament delivery member. Further, and as also described above, when the radially extending protrusion of the syringe collar is arranged in abutment with the proximal end portion of the axially extending track of the portion of the housing, the force from generated from the motion of the syringe collar will also not be absorbed by the medicament delivery member.
According to an example embodiment, the proximal end of the rotator may comprise a surface portion arranged in abutment with a distally facing surface portion of the housing when the medicament delivery device assumes the protracted state. Hereby, any axial forces generated in the rotator during the transition from the protracted state to the retracted state can be absorbed by the housing at the distal facing surface portion.
According to an example embodiment, the medicament delivery device may further comprise a plunger rod configured to interact with the syringe collar. When the plunger rod interacts with the syringe collar, the plunger rod preferably interacts with the syringe collar via the medicament container. Thus, the plunger rod interacts with the medicament container, i.e. the plunger rod is arranged in mechanical contact with the medicament container. The medicament container is in turn interacting with the syringe collar, i.e. the medicament container and the syringe collar are in mechanical contact with each other.
According to an example embodiment, the medicament delivery device may further comprise a plunger spring connected to a proximal end portion of the plunger rod, the plunger spring being pre-tensioned when the medicament delivery device assumes the retracted state, and arranged to exert a force on the proximal end portion of the plunger rod to force the plunger rod towards the medicament container during the transition from the retracted state to the protracted state.
The plunger rod is preferably moved in the proximal direction when the medicament delivery device transitions from the retracted state to the protracted state for forcing medicament out from the medicament container.
According to an example embodiment, the medicament delivery device may further comprise an activation mechanism, the medicament delivery device being arranged to transition from the retracted state to the protracted state upon actuation of the activation mechanism. The activation mechanism is preferably arranged at a distal end portion of the medicament delivery device and accessible by e.g. the thumb of the hand holding the medicament delivery device.
Generally, all terms used in the claims are to be interpreted according to their ordinary meaning in the technical field, unless explicitly defined otherwise herein. All references to “a/an/the member, apparatus, component, means, etc.” are to be interpreted openly as referring to at least one instance of the member, apparatus, component, means, etc., unless explicitly stated otherwise.
The specific embodiments of the inventive concept will now be described, by way of example, with reference to the accompanying drawings, in which:
The inventive concept will now be described more fully hereinafter with reference to the accompanying drawings, in which exemplifying embodiments are shown. The inventive concept may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein; rather, these embodiments are provided by way of example so that this disclosure will be thorough and complete, and will fully convey the scope of the inventive concept to those skilled in the art. Like numbers refer to like members throughout the description.
Reference is made to
The needle cap 102 is arranged at the proximal end 101 of the medicament delivery device 100 and is provided as a cover before usage of the medicament delivery device 100. In further detail, the needle cap 102 prevents components, such as a rigid needle shield 122 and an injection needle (202 in e.g.
The needle cap 102 also comprises an axially elongated portion 136. The axially elongated portion 136 extends distally and is arranged radially between the needle cover 105 and the rigid needle shield 122. In particular, the axially elongated portion 136 is at a distal end (not shown) attached to a distal end 122″ of the rigid needle shield 122. When the needle cap 102 is removed, i.e. moved proximally in the axial direction, the attachment between the axially elongated portion 136 of the needle cap 102 and the distal end 122″ of the rigid needle shield 122 causes also the rigid needle shield 122 to be moved proximal in the axial direction and subsequently removed.
The interaction between the above described components will be evident from the below disclosure detailing the functionality of the medicament deliver device 100 with reference to
As can be seen in
The needle cover spring 111 is supported between a radially extending floor portion 204 of the needle cover 105 and a spring abutment surface 206 of the syringe collar 113. In detail, the proximal end 111′ of the needle cover spring 111 is arranged in abutment with the radially extending floor portion 204 of the needle cover 105 and the distal end 111″ of the needle cover spring 111 is arranged in abutment with the spring abutment surface 206 of the syringe collar 113.
With reference to
Furthermore, the syringe collar 113, which is at least partly housed by the rotator 111, i.e. the syringe collar 113 is positioned radially inside the rotator 111, comprises a radially extending protrusion 216. The radially extending protrusion 216 is arranged at a distal end 218 of the syringe collar 113 and extends radially from the distal end 218 in a direction away from the axially extending geometric center axis 212. s extending protrusion 216 is arranged in a second axially extending track 220 of the rotator 112. The second axially extending track 220 comprises an inclined surface portion 222, which inclined surface portion 222 is, in the state depicted in
In the state depicted in
Reference is now made to
As can be seen in
As can be seen in
As is also illustrated in
The following will now describe the state when the medicament delivery device 100 is activated to initiate the transition from a retracted state, in which the injection needle 202 is arranged inside the needle cover 105 and prevented from external exposure, to a protracted state in which the injection needle 202 protrudes proximally from the proximal end of the needle cover 105. Reference is therefore made to
As can be seen in
Turning now to
As can be seen in
As can be seen in
When the radially extending protrusion 216 moves in the proximal direction in the second axially extending track 220, the radially extending protrusion 216 engages with the inclined surface portion 222 of the second axially extending track 220, generating a rotation of the rotator 112 in the same rotational direction as the rotation of the rotator 112 generated by the protrusion 208 of the needle cover 105 described above in relation to
Turning to
Reference is now made to
As can be seen in
With reference to
Reference is now finally made to
As can be seen in
The above described
The inventive concept has mainly been described above with reference to a few examples. However, as is readily appreciated by a person skilled in the art, other embodiments than the ones disclosed above are equally possible within the scope of the inventive concept, as defined by the appended claims.
Number | Date | Country | Kind |
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21203581.0 | Oct 2021 | EP | regional |
The present application is a U.S. National Phase Application pursuant to 35 U.S.C. § 371 of International Application No. PCT/EP2022/077871 filed Oct. 6, 2022, which claims priority to European Patent Application No. 21203581.0 filed Oct. 19, 2021. The entire disclosure contents of these applications are herewith incorporated by reference into the present application.
Filing Document | Filing Date | Country | Kind |
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PCT/EP2022/077871 | 10/6/2022 | WO |