A NEW DEVICE FOR MICRODOSIMETRY

Information

  • Research Project
  • 3506642
  • ApplicationId
    3506642
  • Core Project Number
    R44CA045869
  • Full Project Number
    2R44CA045869-02A2
  • Serial Number
    45869
  • FOA Number
  • Sub Project Id
  • Project Start Date
    9/30/1990 - 34 years ago
  • Project End Date
    9/29/1992 - 32 years ago
  • Program Officer Name
  • Budget Start Date
    9/30/1990 - 34 years ago
  • Budget End Date
    9/29/1991 - 33 years ago
  • Fiscal Year
    1990
  • Support Year
    2
  • Suffix
    A2
  • Award Notice Date
    9/21/1990 - 34 years ago

A NEW DEVICE FOR MICRODOSIMETRY

This proposal deals with the development of a radiation detector system that will make possible the direct measurement of the structure of charged particle tracks in a gas. Such a detector will permit the measurement of energy e.g., the diameter of a DNA molecule. This information, which is critical to development and evaluation of mechanistic biophysical models for understanding radiation effects, has hereto fore not been measurable. When a charged particle penetrates a gas, electrons produced during ionization events quickly become thermalized. The proposed detector system will determine the positions and number of these electrons by imposing a suitable RF field, causing the electrons to agitate and excite molecules of the gas which will then fluoresce producing photons that will be detected by the external optical detector system. Thus, each point of light will represent the position of a single electron. In Phase I experimental proof of the concept was made that a single charged particle track can be detected optically. In this proposal the operation of the system would be greatly enhanced so that CCD detectors can be used to obtain quantitative information from images of all of the electrons produced in the track of a single particle.

IC Name
NATIONAL CANCER INSTITUTE
  • Activity
    R44
  • Administering IC
    CA
  • Application Type
    2
  • Direct Cost Amount
  • Indirect Cost Amount
  • Total Cost
  • Sub Project Total Cost
  • ARRA Funded
  • CFDA Code
    395
  • Ed Inst. Type
  • Funding ICs
  • Funding Mechanism
  • Study Section
    SSS
  • Study Section Name
  • Organization Name
    PELLISSIPPI INTERNATIONAL
  • Organization Department
  • Organization DUNS
  • Organization City
    KNOXVILLE
  • Organization State
    TN
  • Organization Country
    UNITED STATES
  • Organization Zip Code
    37932
  • Organization District
    UNITED STATES