Acquisition of a Confocal Laser Scanning Microscope

Information

• NSF Award
• 9202417

Owner

• WISTAR INSTITUTE

• Award Id

  9202417

• Award Effective Date

  9/1/1993 - 31 years ago

• Award Expiration Date

  2/29/1996 - 28 years ago

• Award Amount

  $ 127,084.00

• Award Instrument

  Standard Grant

9202417 Maul This proposal requests the funds for a confocal microscope to be used by a multi-user group. The major users will utilize the instrument in projects over the long term. Projects include the 3D reconstruction of changing chromosomal domains during differentiation and of specific and newly found nuclear domains, the changing inter- relationships of cells during development or induced differentiation by retinoic acids or by coculture in skin reconstruction, the different distribution of mRNA in whole developing embryos, and the relative localization of specific genes in the intact nucleus (mapping). Aside from these larger projects minor projects have been identified and initiated by different laboratories at The Wistar Institute in particular in the developing structural biology program. These will be supervised by the principal investigator. Projects are diverse and need an efficient way to study cell or tissue architecture in the 0.1 to 1 m range in specimens that have a thickness of 0.1-1-mm. Confocal microscopy in its advanced state provides us with the means to achieve our goals.

• Program Officer

  Michael K. Lamvik

• Min Amd Letter Date

  8/20/1993 - 31 years ago

• Max Amd Letter Date

  8/20/1993 - 31 years ago

• ARRA Amount

• Name

  Wistar Institute

• City

  Philadelphia

• State

  PA

• Country

  United States

• Address

  3601 Spruce Street

• Postal Code

  191044268

• Phone Number

  2158983700

• First Name

  Donald

• Last Name

  Ewert

• Start Date

  9/1/1993 12:00:00 AM

• First Name

  Gerd

• Last Name

  Maul

• Email Address

  maul@wistar.org

• Start Date

  9/1/1993 12:00:00 AM

• First Name

  Clayton

• Last Name

  Buck

• Start Date

  9/1/1993 12:00:00 AM

• First Name

  Peter

• Last Name

  Andrews

• Start Date

  9/1/1993 12:00:00 AM

• First Name

  Meenhard

• Last Name

  Herlyn

• Email Address

  herlynm@wista.wistar.upenn.edu

• Start Date

  9/1/1993 12:00:00 AM

• Name

  Health

• Code

  203000

• Name

  Life Science Biological

• Code

  61