Acquisition of Circular Dichroism Spectropolarimeter

Information

• NSF Award
• 0618713

Owner

• BELOIT CORPORATION

• Award Id

  0618713

• Award Effective Date

  9/1/2006 - 18 years ago

• Award Expiration Date

  8/31/2009 - 15 years ago

• Award Amount

  $ 145,594.00

• Award Instrument

  Standard Grant

This award is for the acquisition of a circular dichroism (CD) spectropolarimeter with stopped flow and total fluorescence accessories. This instrument will be used to measure the denaturation transition and conformational unfolding of DNA oligomers and proteins due to confinement effects. The investigators will use the CD instrumentation to complement Differential Scanning Calorimetry and Isothermal Titration Calorimetry for the following uses: to monitor conformational ordering upon DNA duplex formation, to determine whether this parameter is sequence dependent, to measure denaturation process of trinucleotide DNA duplex, and to measure conformational change upon drugs binding to DNA. <br/><br/>Acquisition of this CD instrumentation will greatly enhance inquiry-based curriculum in the general chemistry, biochemistry, inorganic chemistry and physical chemistry courses at the college, in addition to its benefits for undergraduate student researchers. Acquisition of this instrumentation also strengthens the collaboration between this undergraduate college and Argonne National Laboratory.

• Program Officer

  Steven E. Ellis

• Min Amd Letter Date

  7/25/2006 - 18 years ago

• Max Amd Letter Date

  7/25/2006 - 18 years ago

• ARRA Amount

• Name

  Beloit College

• City

  BELOIT

• State

  WI

• Country

  United States

• Address

  700 COLLEGE STREET

• Postal Code

  535115509

• Phone Number

  6083632201

• First Name

  Kathleen

• Last Name

  Mandell

• Email Address

  mandellk@beloit.edu

• Start Date

  7/25/2006 12:00:00 AM