Claims
- 1. In a manufactured consumer product for application to or consumption by the human body, said product comprising a vehicle topically administrable to or consumable by the human body and containing as an adjuvant in said vehicle, a compound capable of stimulating the cold receptors of the nervous system in the surface tissues of the body when brought into contact therewith by topical application or consumption of the said vehicle, said product being:
- (i) A toiletry comprising a topically administrable vehicle containing as adjuvants therein a) said cold receptor stimulating compound and b) at least one of the following: an odourant, antiseptic, colourant or surfactant;
- (ii) a foodstuff or beverage comprising an orally ingestible vehicle containing as adjuvants therein
- (a) said cold receptor stimulating compound and b) a flavourant; or
- (iii) a tobacco or tobacco-containing manufacture containing said cold receptor stimulating compound;
- the improvement which comprises using as said cold receptor stimulating compound an effective amount of a cold receptor stimulating acyclic carboxamide of the formula: ##STR5## wherein R' and R" are each methyl or ethyl;
- R.sub.1 is methyl, ethyl or n-propyl;
- R.sub.2 and R.sub.3 are each C.sub.1 -C.sub.5 alkyl, with the proviso that at least one of R.sub.2 and R.sub.3 is branched at the carbon atom in the alpha or beta position;
- R.sub.1, r.sub.2 and R.sub.3 together providing a total of at least 5 carbon atoms.
- 2. A product according to claim 1, which is a toilet or cosmetic lotion comprising an aqueous, alcoholic or aqueous alcoholic carrier, an antiseptic or odorant, and an effective amount of said cold receptor stimulating compound.
- 3. A product according to claim 1, which is a toilet or cosmetic lotion or cream comprising an oleaginous carrier, an antiseptic or odorant, and an effective amount of said cold receptor stimulating compound.
- 4. A product according to claim 1, which is a shaving foam preparation comprising a foamable base, a surfactant, an odorant, or antiseptic, and an effective amount of said cold receptor stimulating compound.
- 5. A product according to claim 1, which is a dentifrice comprising an effective amount of said cold receptor stimulating compound.
- 6. A product according to claim 1, which is a mouthwash comprising an aqueous or aqueous-alcoholic carrier, an antiseptic, and an effective amount of said cold receptor stimulating compound.
- 7. In a foodstuff or beverage for human consumption comprising an edible or potable carrier and, as adjuvants therein, a flavorant and a compound capable of stimulating the cold receptors of the nervous system in the surface tissues of the mouth upon ingestion of the said foodstuff or beverage, the improvement which comprises using as said cold receptor stimulating compound an effective amount of a cold receptor stimulating acyclic carboxamide of the formula defined in claim 1.
- 8. In a chewing gum, comprising an edible chewing gum base, a flavorant and a compound capable of stimulating the cold receptors of the nervous system in the surface tissues of the mouth upon chewing said gum the improvement which comprises using as said cold receptor stimulating compound an effective amount of a cold receptor stimulating acyclic carboxamide of the formula defined in claim 1.
- 9. In a tobacco or tobacco-containing preparation comprising tobacco and a compound capable of stimulating the cold receptors of the nervous system in the surface tissues of the nose or mouth when said tobacco is ingested, or the smoke therefrom is inhaled, the improvement which comprises using as said cold receptor stimulating compound an effective amount of a cold receptor stimulating acyclic carboxamide of the formula defined in claim 1.
- 10. A tobacco preparation according to claim 9, which is a cigarette containing an effective amount of said cold receptor stimulating compound.
- 11. A tobacco preparation according to claim 9, which is a filter tip containing an effective amount of said cold receptor stimulating compound impregnated in the filter tip.
- 12. A method of stimulating the cold receptors of the nervous system in the surface tissues of the human body which comprises contacting said receptors with an effective amount of a cold receptor stimulating acyclic carboxamide of the formula: ##STR6## wherein R' and R" are each methyl or ethyl;
- R.sub.1 is methyl, ethyl or n-propyl;
- R.sub.2 and R.sub.3 are each C.sub.1 -C.sub.5 alkyl, with the proviso that at least one of R.sub.2 and R.sub.3 is branched at the carbon atom in the alpha or beta position;
- R.sub.1, r.sub.2 and R.sub.3 together providing a total of at least 5 carbon atoms.
Priority Claims (1)
Number |
Date |
Country |
Kind |
17914/72 |
Apr 1972 |
GBX |
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Parent Case Info
This is a division of application Ser. No. 351,357, filed Apr. 16, 1973 now abandoned.
US Referenced Citations (5)
Non-Patent Literature Citations (1)
Entry |
Chemical Abstracts 72: 70581a (1969). |
Divisions (1)
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Number |
Date |
Country |
Parent |
351357 |
Apr 1973 |
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