Claims
- 1. A compound of the formula
- R.sub.1 - Ph - X - alk - R.sub.2
- wherein R.sub.1 is unsubstituted adamantyl, Ph is unsubstituted phenylene, or phenylene substituted by nitro, lower alkyl, lower alkoxy, halogeno or trifluoromethyl, X is thio, sulphinyl or sulphonyl, alk is alkylene with up to 10 carbon atoms which may be branched in the .alpha.-position with respect to R.sub.2 , or alkenylene with up to 7 atoms the double bond of which extends from the carbon atom in .alpha.- or .beta.-position to R.sub.2 , and which may be branched in the .beta.-position with respect to R.sub.2 , and R.sub.2 is carboxyl, lower alkoxycarbonyl, pyridyloxycarbonyl, pyridylcarbonyloxy or pyridylmethoxycarbonyl, or a therapeutically acceptable salt thereof.
- 2. A compound as claimed in claim 1, wherein R.sub.1 is unsubstituted adamantyl, Ph is 1,4-phenylene, X is thio, alk is -(CH.sub.2 ).sub.n -CH(R.sub.3 )-, wherein n is 0, 1 or 2 and R.sub.3 is hydrogen or straight-chain alkyl with 1 to 8 C atoms, and R.sub.2 is carboxyl, methoxycarbonyl, ethoxycarbonyl or pyridylmethoxycarbonyl, or a therapeutically acceptable salt thereof.
- 3. A compound as claimed in claim 1, wherein R.sub.1 is unsubstituted adamantyl, Ph is 1,2- or 1,4-phenylene which are optionally substituted by nitro, methoxy, methyl or chlorine, X is thio, alk is unbranched alkylene with 1 to 4 C atoms which can carry unbranched alkyl with 1 to 8 C atoms in the .alpha.-position to R.sub.2 , or is unbranched alkenylene with 2 or 3 C atoms which can carry unbranched alkyl with 1 to 3 C atoms in the .alpha.-position or .beta.-position to R.sub.2 , and R.sub.2 is carboxyl, C.sub.1 -C.sub.4 -alkoxycarbonyl, pyridyloxycarbonyl, pyridylmethoxycarbonyl, or a therapeutically acceptable salt thereof.
- 4. A compound as claimed in claim 1, wherein R.sub.1 is unsubstituted adamantyl, Ph is 1,4-phenylene, X is thio, alk is unbranched alkylene with 1 to 4 C atoms or is unbranched alkenylene with 2 or 3 C atoms and R.sub.2 is carboxyl, C.sub.1 -C.sub.3 -alkoxycarbonyl, pyridyloxycarbonyl or pyridylmethoxycarbonyl, or a therapeutically acceptable salt thereof.
- 5. A compound as claimed in claim 1 being 4-[4-(1-adamantyl)-phenylthio]-butyric acid ethyl ester.
- 6. A compound as claimed in claim 1 being 4-[4-(1adamantyl)-phenylthio]-butyric acid or a therapeutically acceptable salt thereof.
Priority Claims (2)
Number |
Date |
Country |
Kind |
15923/72 |
Nov 1972 |
CH |
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13386/73 |
Sep 1973 |
CH |
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Parent Case Info
This is a division of application Ser. No. 409,192, filed Oct. 24, 1973, now U.S. Pat. No. 3,933,835.
US Referenced Citations (1)
Number |
Name |
Date |
Kind |
3928363 |
Haas et al. |
Dec 1975 |
|
Divisions (1)
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Number |
Date |
Country |
Parent |
409192 |
Oct 1973 |
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