Claims
- 1. An agent for the immunochemical detection or determination of an analysis substance in a sample of biological material comprising:
- (a) at least one immunochemical reactant being capable of reacting with the analysis substance and being bonded to a solid phase; and
- (b) an aqueous solution of a water-soluble polymer containing carboxyl groups selected from the group consisting of polyacrylic acid, polymaleic acid, polymers or telomers of maleic anhydride and methyl vinyl ether or ethylene or propylene or octadecene, the anhydride rings of which are opened by hydrolysis, and polygalacturonic acid, said polymer being present in said aqueous solution in a concentration of 0.1 to 50 g/L.
- 2. An agent as claimed in claim 1, wherein the polymer containing carboxyl groups is polyacrylic acid.
- 3. An agent as claimed in claim 1, wherein the polymer containing carboxyl groups is obtained by alkaline hydrolysis of maleic anhydride-propylene polymer.
- 4. An agent as claimed in claim 1, wherein the polymer containing carboxyl groups is obtained by alkaline hydrolysis of maleic anhydride-methyl vinyl ether polymer.
- 5. An agent for the immunochemical detection or determination of an analysis substance in a sample of biological material comprising:
- (a) dry chemical test device coated with a water-soluble polymer containing carboxyl groups selected from the group consisting of polyacrylic acid, polymaleic acid, polymers or telomers of maleic anhydride and methyl vinyl either or ethylene or propylene or octadecene, the anhydride rings of which are opened by hydrolysis, and polygalacturonic acid, said device having been coated with said polymer in a concentration of 0.1 to 50 g/L; and,
- (b) at least one immunochemical reactant being capable of reacting with the analysis substance.
- 6. A process for the immunochemical determination of an analysis substance contained in a sample of biological material, which comprises the steps of:
- (a) applying an aqueous solution containing the analysis substance and a water-soluble polymer containing carboxyl groups selected from the group consisting of polyacrylic acid, polymaleic acid, polymers or telomers of maleic anhydride and methyl vinyl ether or ethylene or propylene or octadecene, the anhydride rings of which are opened by hydrolysis, and polygalacturonic acid, said polymer being present in a concentration of 0.01 to 50 g/L, to an immunochemical reactant present on a solid phase and being capable of reacting with the analysis substance;
- (b) separating the solid phase from the liquid phase; and
- (c) determining the analysis substance either in the solid phase or in the liquid phase by using an immunochemical reactant carrying a detectable label.
- 7. A process for the immunochemical determination of an analysis substance contained in a sample of biological material, which comprises the steps of:
- (a) applying an aqueous solution containing the analysis substance and a water-soluble polymer containing carboxyl groups, present in a dry form before addition to the aqueous solution, selected from the group consisting of polyacrylic acid, polymaleic acid, polymers or telomers of maleic anhydride and methyl vinyl either or ethylene or propylene or octadecene, the anhydride rings of which are opened by hydrolysis, and polygalacturonic acid, in a concentration of 0.01 to 50 g/L in the aqueous solution, to an immunochemical reactant capable of reacting with the analysis substance and present on a solid phase; and,
- b) determining the amount of analysis substance bound to the immunochemical reactant.
- 8. A process for the immunochemical determination of an analysis substance contained in a sample of biological material, which comprises the steps of:
- (a) adding to an aqueous solution containing the analysis substance a dry chemical test device coated with a water-soluble polymer containing carboxyl groups selected from the group consisting of polyacrylic acid, polymaleic acid, polymers or telomers of maleic anhydride and methyl vinyl ether or ethylene or propylene or octadecene, the anhydride rings of which are opened by hydrolysis, and polygalacturonic acid, said device having been coated with said polymer in a concentration of 0.01 to 50 g/L; and an immunochemical reactant present on a solid phase and being capable of reacting with the analysis substance;
- (b) separating the solid phase from the liquid phase; and
- (c) determining the analysis substance either in the solid phase or in the liquid phase by using an immunochemical reactant carrying a detectable label.
Priority Claims (1)
Number |
Date |
Country |
Kind |
3840605.5 |
Dec 1988 |
DEX |
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Parent Case Info
This application is a continuation, of application Ser. No. 07/443,312, filed Nov. 30, 1989, abandoned.
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Continuations (1)
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Number |
Date |
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Parent |
443312 |
Nov 1989 |
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