Claims
- 1. A method of therapy using IL-8 to promote maturity of the uterine cervix in late phase pregnancy, comprising the steps of:(a) administering an amount of IL-8 to a subject in need of said therapy; and (b) administering to the subject dehydroepiandrosterone sulfate (DHAS) or a pharmaceutically acceptable salt thereof in an amount that potentiates the therapeutic effect of IL-8, thereby promoting maturity of the uterine cervix in late phase pregnancy in the subject.
- 2. The method of claim 1, wherein said IL-8 therapy increases activity of collagenolytic enzymes.
- 3. The method of claim 2, wherein said collagenolytic enzymes are collagenase, elastase or gelatinase.
- 4. The method of claim 1, wherein the subject is human.
CROSS-REFERENCE TO RELATED APPLICATION
This application claims priority based on PCT Application No. PCT/JP96/01774 filed Jun. 27, 1996 identifying the United States as an elected country.
PCT Information
Filing Document |
Filing Date |
Country |
Kind |
102e Date |
371c Date |
PCT/JP96/01774 |
|
WO |
00 |
10/14/1998 |
10/14/1998 |
Foreign Referenced Citations (2)
Number |
Date |
Country |
3209328 |
Sep 1991 |
JP |
6299328 |
May 1997 |
JP |