Patent Application
20200404904
The present invention relates to agrochemical oil dispersions and methods of preparation thereof, wherein said agrochemical oil dispersions contain thickeners selected among N-acyl amino acid alkylamides.
A great potential still exists to improve pesticide efficiency and thus reduce their input into the environmental and food chain. Proper formulations and efficient delivery systems are the key elements in the performance of any product. One of the most important ways to improve the efficacy of pesticides and minimize their impact on non-target organisms is through increased penetration of active ingredient into plant foliage. For this reason, the use of vegetable oils (seed oils), together with the use of non-noxious products, has been recently increased since they are more biodegradable and originate from renewable resources. In addition, these oils are very useful in pesticide formulations as the oil is expected to contribute to the biological activity of the plant.
In this context, agrochemical formulations such as oil dispersions (OD) are attracting increasing interest. Oil dispersions are liquid formulations defined as stable suspensions of active ingredients in a water-immiscible fluid, which may contain other dissolved active ingredients, and are intended for dilution with water before use.
Oil dispersion (OD), as a formulation type in the pesticide industry, has become more important over the past few years. This increased importance is due to: new moisture-sensitive active ingredients; poor compatibility of active ingredient mixtures; the need to improve adjuvancy properties; customer preference of liquid formulations.
A disadvantage of the existing OD formulations is that such formulations frequently show phase separation after storage. Thus, storage even at ambient temperatures frequently leads to aggregation effects, lump formation or pronounced settling of the suspended phase. In the worst cases, the effects are irreversible, i.e. even shearing, for example by stirring, cannot re-homogenize the formulation.
A common method to solve this problem is to add to the dispersions, as anti-settling agent, a thickener that increases the viscosity of the system and acts as suspending agent by reducing the settling rate of the particles.
Typical thickeners for waterless organic systems include organoclays, such as Bentone®. Organoclays are made from natural smectite, hectorite or montmorillonite clays by reacting the hydrophilic clay with quaternary ammonium compounds, so that it becomes organophilic and therefore compatible with non-aqueous media. The use of these thickeners is described for example in WO 2009/004281, EP 789,999, GB 2,067,407, EP 149,459 and GB 2,008,949. Unfortunately, organoclays have to be carefully dispersed and need the presence of a chemical activator in order to function as anti-settling agents with good gel strength. If the organoclay is not well dispersed or chemically activated, the result is poor gel strength and hence limited physical stability of the product.
Other known thickeners are vegetable oil derivatives, silica derivatives and synthetic polymers that are described, for example, in WO 2008/135854 and U.S. Pat. No. 5,599,768.
In more recent years, also polyamides have been proposed and used as thickeners for oil dispersions. In this field, Patent Application WO 2012/080208 describes the preparation of an agrochemical oil dispersion comprising a thickener which is an amide obtained by reacting a polyhydroxystearic acid with diethylene triamine and/or triethylene tetramine. Patent Application WO 2015/145105 relates to agrochemical oil-based active formulations comprising a thickener based on a polyamide derived from a dimer fatty acid and a diamine.
The handling of most of prior art thickeners is very difficult and/or harmful because they are mainly very fine and light powders. In addition, said thickeners are difficult to dissolve and homogenize without the formation of gels or lumps and continued and careful monitoring of the process is required.
Moreover, the polyamide-based thickeners of the prior art tend to lose efficacy in their thickening properties when raising the temperature, so that it is difficult to obtain acceptable agrochemical oil-based formulations, i.e. which are sufficiently stable at 54° C. for at least 14 days, as the FAO Pesticide Specifications recommend.
For these reasons, a need still exists for a polyamide-based thickener that improves the physical stability of oil dispersions and oil suspension concentrates of a variety of agrochemical active ingredients.
We have now found that thickeners based on N-acyl amino acid alkylamides can be used to prepare agrochemical oil dispersions which are stable at 54° C. for at least 14 days.
Accordingly, the present invention concerns thickeners suitable for preparing a stable dispersion of agrochemical ingredients in an oil, said dispersion and a method for forming said dispersion.
It is therefore an object of the present invention an agrochemical oil dispersion comprising:
wherein:
A further object of the invention is a method of preparing the above mentioned agrochemical dispersion comprising the following steps:
Preferably, the agrochemical oil dispersion of the invention comprises:
According to another preferred embodiment, the agrochemical oil dispersion of the invention comprises:
The N-acyl amino acid alkylamides of Formula (I) are derivatives of glutamic acid (i.e. n=2) or aspartic acid (i.e. n=1). Preferably, they are derivatives of glutamic acid.
Particularly preferred N-acyl amino acid alkylamides are N-lauroyl-L-glutamic acid dibutylamide, also referred to as dibutyllauroyl glutamide (commercially available from Ajinomoto Co., under the trade name “Gelatinization Agent GP-1”) and N-2-ethylhexanoyl-L-glutamic acid dibutylamide (commercially available from Ajinomoto Co., under the trade name “Gelatinization Agent EB-21”). Although these compounds are well known as gelling agents for oil phases, their use as thickeners for preparing stable agrochemical oil dispersions, whose preparation is usually a challenging task, is not described, as far as the Applicant knows.
According to another embodiment, other suitable N-acyl amino acid alkylamides are N-cocoyl-L-glutamic acid dibutylamide and N-cocoyl-L-glutamic acid dicocoylamide
Suitable agrochemical active ingredients of the agrochemical oil dispersion are substantially solid materials that are oil-insoluble at room temperature such as, for example, fungicides, bactericides, insecticides, acaricides, nematicides, herbicides, aracnicides, insect growth regulators, repellents, plant growth regulators, plant nutrients or mixtures thereof. Preferably, the agrochemical active ingredient is selected among fungicides, bactericides, insecticides, acaricides, nematicides, herbicides, aracnicides or mixtures thereof.
Examples of fungicides which may be mentioned are:
2-anilino-4-methyl-6-cyclopropyl-pyrimidine; 2′,6′-dibromo-2-methyl-4′-trifluoro-methoxy-4′-trifluoromethyl-1,3-thiazole-5-carboxanilide; 2,6-dichloro-N-(4-trifluoro-methylbenzyl)-benzamide; (E)-2-methoximino-N-methyl-2-(2-phenoxyphenyl)-acetamide; 8-hydroxyquinoline sulphate; methyl(E)-2-{2-[6-(2-cyanophenoxy)-pyrimidin-4-yloxy]-phenyl}-3-methoxyacrylate; methyl(E)methoximino[alpha-(o-tolyloxy)-o-tolyl]-acetate; 2-phenylphenol (OPP), aldimorph, ampropylfos, anilazine, azaconazole, benalaxyl, benodanil, benomyl, binapacryl, biphenyl, bitertanol, blasticidin-S, bromuconazole, bupirimate, buthiobate, calcium polysulphide, captafol, captan, carbendazim, carboxin, quinomethionate, chloroneb, chloropicrin, chlorothalonil, chlozolinate, cufraneb, cymoxanil, cyproconazole, cyprofuram, carpropamide, dichlorophen, diclobutrazole, dichlofluanid, diclomezin, dicloran, diethofencarb, difenoconazole, dimethirimol, dimethomorph, diniconazole, dinocap, diphenylamine, dipyrithion, ditalimfos, dithianon, dodine, drazoxolon, edifenphos, epoxyconazole, ethirimol, etridiazole, fenarimol, fenbuconazole, fenfuram, fenitropan, fenpiclonil, fentin acetate, fentin hydroxide, ferbam, ferimzone, fluazinam, fludioxonil, fluoromide, fluquinconazole, flusilazole, flusulfamide, flutolanil, flutriafol, folpet, fosetyl-aluminium, fthalide, fuberidazole, furalaxyl, fenhexamide, guazatine, hexachlorobenzene, hexaconazole, hymexazole, imazalil, imibenconazole, iminoctadine, iprobenfos (IBP), iprodion, isoprothiolan, iprovalicarb, kasugamycin, copper preparations, such as: copper hydroxide, copper naphthenate, copper oxychloride, copper sulphate, copper oxide, oxine-copper and Bordeaux mixture; mancopper, mancozeb, maneb, mepanipyrim, mepronil, metalaxyl, metconazole, methasulfocarb, methfuroxam, metiram, metsulfovax, mydobutanil, nickel dimethyldithiocarbamate, nitrothalisopropyl, nuarimol, ofurace, oxadixyl, oxamocarb, oxycarboxine, pefurazoate, penconazole, pencycuron, phosdiphen, pimaricin, piperalin, polyoxine, probenazole, prochloraz, procymidon, propamocarb, propiconazole, propineb, pyrazophos, pyrifenox, pyrimethanil, pyroquilon, quintozene (PCNB), quinoxyfen, sulphur and sulphur preparations, tebuconazole, tecloftalam, tecnazene, tetraconazole, thiabendazole, thicyofen, thiophanate-methyl, thiram, toldlophos-methyl, tolylfluanid, triadimefon, triadimenol, triazoxide, trichlamide, tricyclazole, tridemorph, trifiumizole, triforin, triticonazole, trifioxystrobin, validamycin A, vinclozolin, zineb, ziram, ciproconazole, dodine, fenamidone, fenexamide, fluopicolide, fluoxastrobin, fosetyl-aluminium, iprovalicarb, pencycuron, prothioconazole, spiroxamina, triadimenol, trifloxystrobin, azoxystrobin, acibenzolar-S-methyl, ciprodinil, mandipropamid, fenpropidin, boscalid, kresoxim-methyl, pyraclostrobin, dimetomorf, fenpropimorf, metraphenone, tolclofos-methyl and 2-[2-(1-chloro-cyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-2,4-dihydro-[1,2,4]-triazole-3-thione.
Examples of bactericides which may be mentioned are:
bronopol, dichlorophen, nitrapyrin, nickel dimethyldithiocarbamate, kasugamycin, octhilinon, furancarboxylic acid, oxytetracycline, probenazole, streptomycin, tecloftalam, copper sulphate and other copper preparations.
Examples of insecticides, acaricides and nematicides which may be mentioned are:
abamectin, acephate, acrinathrin, alanycarb, aldicarb, alphamethrin, amitraz, avermectin, AZ 60541, azadirachtin, azinphos A, azinphos M, azocyclotin, Bacillus thuringiensis, 4-bromo-2-(4-chlorophenyl)-1-(ethoxymethyl)-5-(trifluoromethyl)-pyrrole-3-carbonitrile, bendiocarb, benfuracarb, bensultap, betacyfluthrin, bifenthrin, BPMC, brofenprox, bromophosa, bufencarb, buprofezin, butocarboxine, butylpyridaben, cadusafos, carbaryl, carbofuran, carbophenothion, carbosulfan, cartap, chloethocarb, chlaretoxyfos, chlorfenvinphos, chlorfluazuron, chlormephos, N-[(6-chloro-3-pyridinyl)-methyl]-N′-cyano-N-methyl-ethaneimidamide, chlorpyrifos, chlorpyrifos M, cis-resmethrin, clocythrin, clofentezin, cyanophos, cycloprothrin, cyfluthrin, cyhalothrin, cyhexatin, cypermethrin, cyromazin, deltamethrin, demeton-M, demeton-S, demeton-S-methyl, diafenthiuron, diazinon, dichlofenthion, dichlorvos, dicliphos, dicrotophos, diethion, diflubenzuron, dimethoate, dimethylvinphos, dioxathion, disulfoton, emamectin, esfen valerate, ethiofencarb, ethion, ethofenprox, ethoprophos, etrimphos, fenamiphos, fenazaquin, fenbutatin oxide, fenitrothion, fenobucarb, fenothiocarb, fenoxycarb, fenpropathrin, fenpyrad, fenpyroximate, fenthion, fenvalerate, fipronil, fluazuron, flucycloxuron, flucythrinate, flufenoxuron, flufenprox, fluvalinate, fonophos, formothion, fosthiazate, fubfenprox, furathiocarb, HCH, heptenophos, bexaflumuron, hexythiazox, imidacloprid, iprobenfos, isazophos, isofenphos, isoprocarb, isoxathion, ivermectin, lambdacybalothrin, lufenuron, malathion, mecarbam, mevinphos, mesulfenphos, metaldehyde, methacrifos, methamidophos, methidathion, methiocarb, methomyl, metolcarb, milbemectin, monocrotophos, moxidectin, naled, NC 184, nitenpyram, omethoate, oxamyl, oxydemethon M, oxydeprofos, parathion AL, parathion ML, permethrin, phenthoate, phorate, phosalon, phosmet, phosphamidon, phoxim, pirimicarb, pirimiphos M, pirimiphos A, profenophos, promecarb, propapbos, propoxur, prothiophos, prothoate, pymetrozine, pyrachlophos, pyridaphenthion, pyresmethrin, pyrethrum, pyridaben, pyrimidifen, pyriproxifen, quinalphos, salithion, ebufos, silafluofen, sulfotep, sulprofos, tebufenozide, tebufenpyrad, tebupirimiphos, teflubenzuron, tefluthrin, temephos, terbam, terbufos, tetrachlorvinphos, thiacloprid, thiafenox, thiamethoxam, thiodicarb, thiofanox, thiomethon, thionazine, thuringiensin, tralomethrin, transfluthrin, triarathen, triazophos, triawron, trichlorfon, triflumuron, trimethacarb, vamidothion, XMC, xylylcarb, zetamethrin, ethoprophos, fenpyroximate, methoxyfenozide, spinosad, spirodiclofen, thiacloprid, cypermethrine, alphacypermethrine, alphametrine and metaflumizone.
Examples of herbicides which may be mentioned are:
anilides, such as, for example, diflufenican and propanil; arylcarboxylic acids, such as, for example, dichlorpicolinic acid, dicamba and picloram; aryloxyalkanoic acids, such as, for example, 2,4-D, 2,4-DB, 2,4-DP, Fluroxypyr, MCPA, MCPP and triclopyr; aryloxy-phenoxy-alkanoic acid esters, such as, for example, diclofop-methyl, fenoxapropethyl, Fluazifopbutyl, haloxyfop-methyl and quizalofop-ethyl; azinones, such as, for example, chloridazon and norflurazon; carbamates, such as, for example, chlorpropham, desmedipham, phenmedipham and propham; chloroacetanilides, such as, for example, alachlor, acetochlor, butachlor, metazachlor, metolachlor, pretilachlor and propachlor; dinitroarilines, such as, for example, oryzalin, pendimethalin and trifluralin; diphenyl ethers, such as, for example, acifluorfen, bifenox, fluoroglycofen, fomesafen, halosafen, lactofen and oxyfluorfen; ureas, such as, for example, chlortoluron, diuron, fluometuron, isoproturon, linuron and methabenzthiazuron; hydroxylamines, such as, for example, alloxydim, clethodim, cycloxydim, sethoxydim and tralkoxydim; imidazolinones, such as, for example, imazethapyr, imazamethabenz, imazapyr and imazaquin; nitriles, such as, for example, bromoxynil, dichlobenil and ioxynil; oxyacetamides, such as, for example, mefenacet; sulphonylureas, such as, for example, amidosulfuron, azimsulfuron, bensulfuron-methyl, chlorimuron-ethyl, chlorsulfuron, cinosulfuron, cyclosulfamuron, ethametsulfuron-methyl, ethoxysulfuron, flazasulfuron, flupyrsulfuron-methyl-sodium, foramsulfuron, halosulfuron-methyl, imazosulfuron, iodosulfuron-methyl-sodium, metsulfuron-methyl, nicosulfuron, oxasulfuron, primisulfuron-methyl, prosulfuron, pyrazosulfuron-ethyl, rimsulfuron, sulfometuron-methyl, sulfosulfuron, thifensulfuron-methyl, triasulfuron, tribenuron-methyl, trifloxysulfuron, triflusulfuron-methyl; triketones such as, for example, mesotrione, tembotrione, topramezone, fenquinotrione and sulcotrione; thiocarbamates, such as, for example, butylate, cycloate, diallate, EPTCL, esprocarb, molinate, prosulfocarb, thiobencarb and triallate; triazines, such as, for example, atrazine, cyanazine, simazine, simetryne, terbutryne and terbutylazine; triazinones, such as, for example, hexazinon, metarnitron and metribuzin; others, such as, for example, aminotriazole, benfuresate, bentazone, cinmethylin, clomazone, clopyralid, difenzoqual, dithiopyr, ethofumesate, fluorochloridone, glufosinate, glyphosate, isoxaben, pyridate, quinchlorac, quinmerac, sulfosate and tridiphane, aclodifen, bap, bispyribac-sodium, ethoxysulfuron, flufenacet, isoxadifen ethyl, isoxaflutole, mefenpyr diethyl, florasulam, clodinafop propargyl, pinoxaden, trinexapac ethyl, dimethenamide-P, imazamox, profoxydim, tepraloxidim. In addition, 4-amino-N-(1,1-dimethylethyl)-4,5-dihydro-3-(1-methylethyl)-5-oxo-1H-1,2,4-triazole-carboxamide and 2-((((4,5-dihydro-4-methyl-5-oxo-3-propoxy-1H-1,2,4-triazol-1-yl)carbonyl)amino)sulfonyl) methyl sodium benzoate may be mentioned.
Examples of plant growth regulators which may be mentioned are chlorocholine chloride and ethephon.
Examples of repellents which may be mentioned are diethyl-toluamide, ethylhexane-diol and buto-pyronoxyl.
Examples of plant nutrients which may be mentioned are customary inorganic or organic fertilizers for supplying plants with macro- and/or micro-nutrients, such as: ammonium salts, such as ammonium sulfate, ammonium bisulfate, ammonium salts of carboxylic acids, ammonium chloride, ammonium carbonate, ammonium phosphate, urea and urea derivatives; phosphate sources, such as phosphoric salts (MAP monoammoniumphosphate, DAP diammoniumphosphate); potash sources, like potassium phosphate and mono- or di-potassium carbonate; compounds containing micronutrients and secondary nutrients like Zinc, Manganese, Magnesium, Iron, Calcium, Nickel, Molibdenum, Sulfur, Boron, and their chelated salts; polycarboxylic acids, such as citric acid; and mixture thereof; protein derivatives and hydrolyzed proteins and mixture thereof. Preferred plant nutrients are MAP, ammonium sulfate, sulfur and urea.
Other classes of agrochemical active ingredients that are suitable for being formulated as oil dispersions, such as those which are substantially oil-insoluble solid materials at room temperature, will be clearly understood by those skilled in the art or can be found, for example, in “The Pesticide Manual”, 15th edition, The British Crop Protection Council, 2009, and the literature cited therein.
Preferred classes of agrochemical active ingredients suitable for formulating the oil dispersion of the invention are sulfonylureas, sulfamylureas, sulfonamides, imidazolinones, pyrimidinyloxypyridinecarboxylic or pyrimidyloxybenzoic acid derivatives; triketones; neonicotinoids; avermectins; pyrethroids; bisamides; triazoles; mandelamides and strobilurins; alkanamides; anilinopyrimidines; arylaminopropionic acids; aryloxyalkanoic acids; aryloxyphenoxypropionates; benzamides; benzimidazoles; chloroacetamides; cyclohexanedione oximes; dicarboximides; dinitroanilines; diphenyl ethers; imidazoles; hydroxybenzonitriles; isoxazoles; morpholines; guanidines; carbamates, dithiocarbamates, dimethyldithiocarbamates; phosphonates; phthalimides; sulphamides; non-ester pyrethroids; organophosphorus; oxime carbamates; phenylamides; phosphinic acids; pyrazoles; pyridines; pyridinecarboxamides; pyridinecarboxylic acids; quinolinecarboxylic acids; semi-carbazones; triazines; triazinones; ureas, benzoylureas.
Most preferred agrochemical active ingredients belong to the classes of sulfonylureas or triketones, especially of solfonylureas.
Suitable examples of sulfonylurea herbecides are amidosulfuron, azimsulfuron, bensulfuron-methyl, chlorimuron-ethyl, chlorsulfuron, cinosulfuron, cyclosulfamuron, ethametsulfuron-methyl, ethoxysulfuron, flazasulfuron, flupyrsulfuron-methyl-sodium, foramsulfuron, halosulfuron-methyl, imazosulfuron, iodosulfuron-methyl-sodium, metsulfuron-methyl, nicosulfuron, oxasulfuron, primisulfuron-methyl, prosulfuron, pyrazosulfuron-ethyl, rimsulfuron, sulfometuron-methyl, sulfosulfuron, thifensulfuron-methyl, triasulfuron, tribenuron-methyl, trifloxysulfuron, triflusulfuron-methyl.
Among the sulfonylureas, nicosulfuron is particularly preferred.
Suitable examples of triketones include mesotrione, tembotrione, topramezone, fenquinotrione and sulcotrione.
Among the triketones, mesotrione is particularly preferred.
The lipophilic phase is a water-insoluble, liquid organic medium and may be (but not limited to) any of those agricultural oils commonly used in the trade for making oil dispersions for agricultural use. Suitable agricultural oils in the dispersions of the invention are, for example:
Preferably the lipophilic phase is obtained from renewable resources and is a vegetable oil or a transesterification product thereof. Particularly preferred are corn oil, soybean oil, sunflower oil or rapeseed oil or transesterification products thereof such as rapeseed oil methyl esters, ethyl esters, propyl esters, butyl esters, etc.
The agrochemical oil dispersion of the invention is substantially free of water, i.e. it contains less than 10% by weight, preferably less than 5% by weight of water, more preferably less than 1% by weight.
The agrochemical oil dispersion of the invention comprises from 5 to 30 wt %, preferably from 10 to 25 wt %, of a nonionic surfactant, an anionic surfactant or a mixture thereof, preferably a nonionic surfactant. Surfactants are used not only to improve dispersion and to emulsify oil upon dilution in water, but also to increase suspension stability, wetting ability, penetration and translocation, and to provide the mixing ability and suspension/emulsion stability of a product after dilution.
Suitable non ionic surfactants are:
Preferred nonionic surfactants are polyethoxylated hydroxy fatty acids triglycerides or derivatives thereof, in particular fatty esters thereof. Suitable anionic surfactants are for example:
Preferred anionic surfactants are salts of alkylarylsulfonic and sulfosuccinic acids, and polyelectrolytes from the polycondensation of naphthalenesulfonate and formaldehyde.
The agrochemical oil dispersion of the invention can comprise from 0 to 10 wt % of additional thickeners to improve the stability of the composition. Suitable additional thickeners are natural oils and derivatives thereof (such as hydrogenated castor oil), bentones and modified silica.
The oil dispersion according to the invention can comprise from 0 to 10 wt % of additives commonly used in this field and well known to those expert in the art, such as dispersing agents, wetting agents, antidrift agents, penetrants, stickers and spreaders.
In addition to each of the mentioned components said oil dispersion may also comprise from 0 to 10 wt % of other agronomic additives and “crop management” substances such as oil-soluble agrochemical active ingredients, water mixing and/or water soluble carriers and/or deflocculation agents (e.g., kaolin, lignin compounds), antifoam agents (e.g., silicon-based), antifreeze agents, dyes (e.g., azo dyes), preservatives (e.g., biocide and/or antioxidant), fillers, perfumes, evaporation inhibitors, pH modulators, etc.
According to the invention, the agrochemical oil dispersion can be prepared in any known manner. Advantageously, the thickeners of the invention can be added to the formulation before the milling step. Preferably, the method of preparing the agrochemical dispersion comprises the following steps:
i. preparing a mixture of the thickener of Formula I with the surfactant c), under stirring and by heating at a temperature comprised between 120 and 200° C.
The mixture is then homogeneized and subjected to milling, which can be carried out in a colloid mill, ball mill, sand mill, and preferably in grinding ball mills, so that the final average particle size is below 30 microns, preferably below 20 microns.
The agrochemical oil dispersion can be diluted with water or water solutions of agronomic compounds before use to produce a sprayable composition which is used in treating plants or increasing plant growth. Dilution in water usually results in suspensions, emulsions, suspoemulsions or solutions of the agrochemical active ingredient at a concentration of at least 0.001 g/l. It may be advantageous to add, to the aqueous composition obtained, further agrochemical active substances and/or adjuvants and additives conventionally used for application, for example stickers or antidrift agents.
The invention also relates to aqueous compositions obtained by dilution with water of an oil dispersion according to the present invention.
The invention also relates to a method of treating crop field which comprises applying to the plants or to the locus thereof an effective amount of an aqueous compositions obtained by dilution of an agrochemical oil dispersion according to the present invention. Application may be made by ground or aerial spray equipment.
The agrochemical oil dispersions were prepared by vigorously mixing the at least one thickener of the invention with a nonionic emulsifier, by heating at 150° C. for 30 minutes. Then this mixture was dispersed in a vegetable oil and an agrochemical active ingredient was added. Finally the mixture was homogeneized and milled.
The compositions of the oil dispersions which were prepared are reported in Table 1 and Table 2, where the amounts of each ingredient are indicated in % by weight (wt %). All the obtained oil dispersions of the invention were easily pourable.
The storage stability of the oil dispersions described above was evaluated at 0° C. (according to test method CIPAC 39.3), at room temperature and at 54° C. (according to test method CIPAC 46.3) in order to monitor the presence or absence of formation of an oil phase or of a creamy phase in the composition, the presence or absence of the occurrence of aggregation or precipitation, and the presence or absence of the formation of a supernatant over time. About 100 ml of the agrochemical oil dispersions were sealed in glass containers and allowed to rest at 0° C., at room temperature (r.t.) and in oven at 54° C. The results of the storage stability tests are reported in Table 3.
The storage stability test showed that the thickeners of the invention, unlike the diamides tested in Examples 7, 8 and 9, allow to obtain agrochemical oil dispersions which have a good stability over time also at 54° C.
All the ODs prepared showed good emulsion stability, which was evaluated according to CIPAC method 180.
| Number | Date | Country | Kind |
|---|---|---|---|
| 102018000003500 | Mar 2018 | IT | national |
| Filing Document | Filing Date | Country | Kind |
|---|---|---|---|
| PCT/EP2019/056052 | 3/11/2019 | WO | 00 |
