Claims
- 1. A compound of the formula ##STR15## wherein: m is O or an integer of 1 to 4
- R is hydrogen or lower alkyl of 1 to 6 carbon atoms in the chain;
- R.sub.1 is lower alkyl of 1 to 6 carbon atoms, lower alkenyl of 2 to 6 carbon atoms,
- or phenyl lower alkyl of 1 to 4 carbon atoms in the side chain;
- R.sub.2 is halo or lower alkoxy of 1 to 6 carbon atoms;
- Y is a lower alkyl of 1-6 carbon atoms;
- A and B which may be the same or different, each represents a hydrogen atom, a lower alkyl radical or an acyl radical derived from an organic carboxylic acid having from 1 to 18 carbon atoms.
- 2. 1-[(N-ethyl pyrrolidin 2-yl) acetylamino]2-methoxy 4-amino 5-chloro benzene being a compound of claim 1.
- 3. Pharmaceutically active compositions for suppressing gastric hypersecretion and/or preventing delay in gastric evacuation comprising, as active ingredients, a safe and effective amount of at least one compound of claim 1, in the free form or in the form of a salt, in admixture or conjunction with an inert pharmaceutical excipient.
- 4. A method for treating or preventing gastric ulcers due to gastric hypersecretion and/or delay in gastric evacuation which consists in administering to warm blooded animals suffering or disposed to suffer from said ailments a safe and effective gastric secretory inhibitory amount of a compound of claim 1.
- 5. The method of claim 4 wherein the effective amount ranges from 0.5 mg/kg to 6.6 mg/kg.
- 6. A compound of the formula ##STR16## wherein: m is O or an integer of 1 to 4;
- R is hydrogen or lower alkyl of 1 to 6 carbon atoms in the chain;
- R.sub.1 is lower alkyl of 1 to 6 carbon atoms, lower alkenyl of 2 to 6 carbon atoms, or phenyl lower alkyl of 1 to 4 carbon atoms in the side chain;
- R.sub.2 is halo or lower alkoxy of 1 to 6 carbon atoms;
- A and B, which may be the same or different, each represents a hydrogen atom and a lower alkyl radical y is a lower alkoxy of 1 to 6 carbon atoms.
Priority Claims (1)
Number |
Date |
Country |
Kind |
11868/74 |
Mar 1974 |
UK |
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Parent Case Info
This is a division, of application Ser. No. 558,043, filed Mar. 13, 1975 now U.S. Pat. No. 3,989,834.
US Referenced Citations (2)
Number |
Name |
Date |
Kind |
3729470 |
Vaille |
Apr 1973 |
|
3989834 |
Malen et al. |
Nov 1976 |
|
Divisions (1)
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Number |
Date |
Country |
Parent |
558043 |
Mar 1975 |
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