Claims
- 1. A compound of the Formula (I) ##STR194## wherein A is C.sub.1 to C.sub.5 alkylene which can be substituted by hydroxyl;
- X is a single chemical bond or a double bond;
- R.sup.2 is phenyl, thienyl, or pyridyl each unsubstituted or substituted by one or two or three substituents selected from the group consisting of halogen, C.sub.1 to C.sub.4 alkoxy, acetylamino, or trifluoromethyl; and
- R.sup.3 is hydrogen or C.sub.1 or C.sub.4 aklyl; or a pharmaceutically acceptable acid addition salt thereof.
- 2. An antiarrhythmic pharmaceutical composition which comprises a pharmacologically effective amount of the compound of the Formula (I) as defined in claim 1, or a pharmaceutically acceptable acid addition salt thereof in combination with a pharmaceutically acceptable inert carrier.
- 3. A method of treating arrhythmia in an animal subject which comprises the step of administering to said subject in need of antiarrhythmic treatment, a therapeutically effective amount of the compound of the Formula (I) defined in claim 1 or a pharmaceutically acceptable acid addition salt thereof.
Priority Claims (4)
Number |
Date |
Country |
Kind |
191/183 |
Jan 1983 |
HUX |
|
384/83 |
Feb 1983 |
HUX |
|
385/83 |
Feb 1983 |
HUX |
|
386/83 |
Feb 1983 |
HUX |
|
CROSS REFERENCE TO RELATED APPLICATION
This is a divisional of co-pending application Ser. No. 07/441,370 filed on Nov. 27, 1989 which is a divisional of Ser. No. 07/109,819 filed Oct. 16, 1987 now U.S. Pat. No. 4,897,413, which is a divisional of Ser. No. 06/662,298 filed Sept. 20, 1984, now U.S. Pat. No. 4,703,056.
US Referenced Citations (4)
Number |
Name |
Date |
Kind |
4452989 |
Deckner et al. |
Jun 1984 |
|
4643758 |
Burow, Jr. et al. |
Feb 1987 |
|
4731376 |
Hideg et al. |
Mar 1988 |
|
4933354 |
Ikeguchi et al. |
Jun 1990 |
|
Divisions (3)
|
Number |
Date |
Country |
Parent |
441370 |
Nov 1989 |
|
Parent |
109819 |
Oct 1987 |
|
Parent |
662298 |
Sep 1984 |
|