All natural multivitamin and multimineral dietary supplement formulations for enhanced absorption and biological utilization

Abstract

The present invention includes compositions and methods for a dietary supplement formulation containing a standardized source of plant-derived minerals, one or more natural vitamins or provitamins and one or more natural plant extracts.

Description

Claims

1. A dietary supplement formulation comprising a standardized source of plant-derived minerals, one or more natural vitamins or provitamins, and one or more plant extracts.

2. The supplement of claim 1, wherein the plant-derived minerals are selected from the group consisting of seedlings of Brassica napus, Brassica rapa, Brassica juncea, Medicago sativa, and Oryzae sativa seeds.

3. The supplement of claim 1, wherein the plant-derived minerals comprises one or more of the minerals selected from calcium, magnesium, iron, zinc, selenium, chromium, vanadium, copper, manganese, molybdenum, boron, iodine, strontium, and combinations thereof.

4. The supplement of claim 1, wherein the one or more natural vitamins are selected from vitamin A, beta-carotene alone, carotenoids, lycopene, lutein, zeaxanthin, cryptoxanthin, thiamine (vitamin B1), riboflavin (vitamin B2), niacin (vitamin B3), pantothenic acid (vitamin B5), pyridoxine (vitamin B1), folate (vitamin B9), cyanocobalamin (vitamin B12), vitamin C-complex, vitamin D, vitamin E, tocopherols, tocotrieneols, and combinations thereof.

5. The supplement of claim 1, wherein the one or more standardized phytochemicals comprising, sulforaphanes, isothiocyanates, glucosinolates, glucoraphanin, gluconasturtiin, glucobrassicin, glucoerucin, S-methyl cysteine sulfoxide, indole-3-carbinol, erucin, xanthophylls, carotenoids, lycopene, lutein, cryptoxanthin, beta-carotene, polyphenolics, flavonoids, apigenin, rutin, quercetin, chrysin, hesperidin, bioflavonoids, isoflavones, anthocyanins, chlorogenic acid, ECGC, ellagic acid, catechins, aescin, resveratrol, curcumin, lignins, carnosic acid, rosemarinic acid, gingerol, oleuropein, silymarin, sinigrin, quinic acid, and, combinations thereof.

6. The supplement of claim 1, further comprising a natural polysaccharide ingredient comprising a plant polysaccharide, an algal polysaccharide, a fungal polysaccharide, a bacterial polysaccharide, a plant gum, aloe polysaccharide, and combinations thereof.

7. The supplement of claim 1, wherein the supplement is placed inside an external capsule, a vegetable capsule or a hard gelatin capsule.

8. The supplement of claim 1, wherein supplement is compressed at a pressure greater than 2,000 psi.

9. The supplement of claim 1, wherein about 85% of the nutritional supplements are released from between about 1 to about 8 hours.

10. The supplement of claim 1, wherein the nutritional supplements are in liquid, semi-solid, solid, gummy, gum, encapsulated or table form.

11. The supplement of claim 1, wherein the supplement further comprises one or more excipients.

12. A dietary supplement formulation to support bone health comprising a standardized source of plant-derived zinc, a standardized plant extract comprising vitamin A; beta-carotene, carotenoids, lycopene, lutein, zeaxanthin, cryptoxanthin, thiamine (vitamin B1), riboflavin (vitamin B2), niacin (vitamin B3), pantothenic acid (vitamin B5), pyridoxine (vitamin B1), folate (vitamin B9), cyanocobalamin (vitamin B12), vitamin C-complex, vitamin D, vitamin E, tocopherols, tocotrieneols, and one or more additional nutrients comprising vitamin D, vitamin C, calcium, magnesium, strontium, and boron.

13. The supplement of claim 12, wherein the plant-derived minerals are selected from the group consisting of seedlings of Brassica napus, Brassica rapa, Brassica juncea, Medicago sativa, and Oryzae sativa seeds.

14. The supplement of claim 12, further comprising a natural polysaccharide ingredient comprising a plant polysaccharide, an algal polysaccharide, a fungal polysaccharide, a bacterial polysaccharide, a plant gum, aloe polysaccharide, and combinations thereof.

15. The supplement of claim 12, wherein the plant-derived minerals further comprises one or more of the minerals selected from iron, selenium, chromium, vanadium, copper, manganese, molybdenum, iodine, boron, zinc, and combinations thereof.

16. The supplement of claim 12, wherein the one or more natural vitamins are selected from vitamin A, carotenoids, thiamine (vitamin B1), riboflavin (vitamin B2), niacin (vitamin B3), pantothenic acid (vitamin B5), pyridoxine (vitamin B1), folate (vitamin B9), cyanocobalamin (vitamin B12), vitamin C, vitamin D, vitamin E, tocopherols, tocotrieneols, and combinations thereof.

17. The supplement of claim 12, wherein the composition comprises a bulk powder, a chewable form or is adapted for use by children.

18. The supplement of claim 12, wherein the one or more standardized phytochemicals comprising, sulforaphanes, isothiocyanates, glucosinolates, glucoraphanin, gluconasturtiin, glucobrassicin, glucoerucin, S-methyl cysteine sulfoxide, indole-3-carbinol, erucin, xanthophylls, carotenoids, lycopene, lutein, cryptoxanthin, beta-carotene, polyphenolics, flavonoids, apigenin, rutin, quercetin, chrysin, hesperidin, bioflavonoids, isoflavones, anthocyanins, chlorogenic acid, ECGC, ellagic acid, catechins, aescin, resveratrol, curcumin, lignins, carnosic acid, rosemarinic acid, gingerol, oleuropein, silymarin, sinigrin, quinic acid, and combinations thereof.

19. The supplement of claim 12, wherein the supplement is placed inside an external capsule, a vegetable capsule or a hard gelatin capsule.

20. The supplement of claim 12, wherein supplement is compressed at a pressure greater than 2,000 psi.

21. The supplement of claim 12, wherein about 85% of the nutritional supplements are released from between about 1 to about 8 hours.

22. The supplement of claim 12, wherein the nutritional supplements are in liquid, semi-solid, solid, gummy, gum, encapsulated or table form.

23. The supplement of claim 12, wherein the supplement further comprises one or more excipients.

24. A dietary supplement formulation for enhanced vitamin absorption by suppression of intestinal glucuronidation comprising a standardized source of plant-derived minerals comprising, calcium, magnesium, iron, zinc, selenium, chromium, vanadium, copper, manganese, molybdenum, boron, iodine, and strontium; one or more natural vitamins or provitamins comprising, vitamin A, carotenoids, lycopene, lutein, zeaxanthin, cryptoxanthin, thiamine (vitamin B1), riboflavin (vitamin B2), niacin (vitamin B3), pantothenic acid (vitamin B5), pyridoxine (vitamin B1), folate (vitamin B9), cyanocobalamin (vitamin B12), vitamin C, vitamin D, vitamin E, tocopherols, tocotrieneols; and one or more standardized plant extracts comprising plant phenolic compounds, polyphenolics, flavonoids, apigenin, rutin, quercetin, chrysin, hesperidin, bioflavonoids, isoflavones, anthocyanins, chlorogenic acid, ECGC, ellagic acid, catechins, aescin, resveratrol, curcumin, lignins, tannins, tannic acid, gingerol, and oleuropein.

25. The supplement of claim 24, further comprising a natural polysaccharide ingredient comprising a plant polysaccharide, an algal polysaccharide, a fungal polysaccharide, a bacterial polysaccharide, a plant gum, aloe polysaccharide, and combinations thereof.

26. The supplement of claim 24, wherein the supplement is placed inside an external capsule, a vegetable capsule or a hard gelatin capsule.

27. The supplement of claim 24, wherein supplement is compressed at a pressure greater than 2,000 psi.

28. The supplement of claim 24, wherein about 85% of the nutritional supplements are released from between about 1 to about 8 hours.

29. The supplement of claim 24, wherein the nutritional supplements are in liquid, semi-solid, solid, gummy, gum, encapsulated or table form.

30. The supplement of claim 24, wherein the supplement further comprises one or more excipients.

31. A dietary supplement formulation for modulated mineral absorption containing a standardized source of plant-derived minerals comprising, calcium, magnesium, iron, zinc, selenium, chromium, vanadium, copper, manganese, molybdenum, boron, iodine, and strontium; one or more natural vitamins or provitamins comprising, vitamin A, carotenoids, lycopene, lutein, zeaxanthin, cryptoxanthin, thiamine, riboflavin, niacin, vitamin B-6, folate, vitamin B-12, vitamin C, vitamin D, vitamin E, tocopherols, tocotrieneols; and one or more standardized plant extracts comprising plant phenolic compounds, polyphenolics, flavonoids, apigenin, rutin, quercetin, chrysin, hesperidin, bioflavonoids, isoflavones, anthocyanins, chlorogenic acid, ECGC, ellagic acid, catechins, aescin, resveratrol, curcumin, lignins, tannins, tannic acid, gingerol, and oleuropein.

32. The supplement of claim 31, further comprising a natural polysaccharide ingredient comprising a plant polysaccharide, an algal polysaccharide, a fungal polysaccharide, a bacterial polysaccharide, a plant gum, aloe polysaccharide, and combinations thereof.

33. The supplement of claim 31, wherein the supplement is placed inside an external capsule, a vegetable capsule or a hard gelatin capsule.

34. The supplement of claim 31, wherein supplement is compressed at a pressure greater than 2,000 psi.

35. The supplement of claim 31, wherein about 85% of the nutritional supplements are released from between about 1 to about 8 hours.

36. The supplement of claim 31, wherein the nutritional supplements are in liquid, semi-solid, solid, gummy, gum, encapsulated or table form.

37. The supplement of claim 31, wherein the supplement further comprises one or more excipients.

38. A dietary supplement formulation for overcoming suppression of glutathione transferase by vitamins A or E containing a standardized source of plant-derived minerals comprising, calcium, magnesium, iron, zinc, selenium, chromium, vanadium, copper, manganese, molybdenum, boron, iodine, and strontium; and one or more natural vitamins or provitamins comprising, vitamin A, carotenoids, lycopene, lutein, zeaxanthin, cryptoxanthin, thiamine, riboflavin, thiamine (vitamin B1), riboflavin (vitamin B2), niacin (vitamin B3), pantothenic acid (vitamin B5), pyridoxine (vitamin B1), folate (vitamin B9), cyanocobalamin (vitamin B12), vitamin C, vitamin D, vitamin E, tocopherols, tocotrieneols; and one or more standardized plant extracts comprising one or more of the following, sulforaphanes, isothiocyanates, glucosinolates, glucoraphanin, gluconasturtiin, glucobrassicin, glucoerucin, sinigrin, S-methyl cysteine sulfoxide, indole-3-carbinol, erucin, and combinations thereof.

39. The supplement of claim 38, further comprising a natural polysaccharide ingredient comprising a plant polysaccharide, an algal polysaccharide, a fungal polysaccharide, a bacterial polysaccharide, a plant gum, aloe polysaccharide, and combinations thereof.

40. The supplement of claim 38, wherein the supplement is placed inside an external capsule, a vegetable capsule or a hard gelatin capsule.

41. The supplement of claim 38, wherein supplement is compressed at a pressure greater than 2,000 psi.

42. The supplement of claim 38, wherein about 85% of the nutritional supplements are released from between about 1 to about 8 hours.

43. The supplement of claim 38, wherein the nutritional supplements are in liquid, semi-solid, solid, gummy, gum, encapsulated or table form.

44. The supplement of claim 38, wherein the supplement further comprises one or more excipients.

45. A method of providing a balanced nutritional supplement comprising the steps of selecting one or more standardized source of plant-derived minerals, one or more natural vitamins or provitamins and one or more plant extracts, wherein the one or more components of the supplement are synergistic as measured by bioavailability.

46. The method of claim 45, wherein the composition comprises a standardized source of plant-derived minerals comprising, calcium, magnesium, iron, zinc, selenium, chromium, vanadium, copper, manganese, molybdenum, boron, iodine, and strontium; one or more natural vitamins or provitamins comprising, vitamin A, carotenoids, lycopene, lutein, zeaxanthin, cryptoxanthin, thiamine (vitamin B1), riboflavin (vitamin B2), niacin (vitamin B3), pantothenic acid (vitamin B5), pyridoxine (vitamin B1), folate (vitamin B9), cyanocobalamin (vitamin B12), vitamin C, vitamin D, vitamin E, tocopherols, tocotrieneols; and one or more standardized plant extracts comprising plant phenolic compounds, polyphenolics, flavonoids, apigenin, rutin, quercetin, chrysin, hesperidin, bioflavonoids, isoflavones, anthocyanins, chlorogenicpantothenic acid, ECGC, ellagic acid, catechins, aescin, resveratrol, curcumin, lignins, tannins, tannic acid, gingerol, oleuropein, and combinations thereof.

47. The method of claim 45, wherein the supplement is placed inside an external capsule, a vegetable capsule or a hard gelatin capsule.

48. The method of claim 45, wherein supplement is compressed at a pressure greater than 2,000 psi.

49. The method of claim 45, wherein about 85% of the nutritional supplements are released from between about 1 to about 8 hours.

50. The method of claim 45, wherein the nutritional supplements are in liquid, semi-solid, solid, gummy, gum, encapsulated or table form.

51. The method of claim 45, wherein the supplement further comprises one or more excipients.