Claims
- 1. A method for treating lipidemia in mammals comprising administering to a mammal in need of such treatment an effective amount therefor of a compound of the formula: ##STR9## wherein R.degree. is branched alkyl of 3 to 5 carbon atoms,
- R is hydrogen, alkyl of 1 to 4 carbon atoms or halo of atomic weight of from 18 to 36,
- n is 1 or 2,
- R' is hydrogen, alkyl of 1 to 4 carbon atoms, halo of atomic weight of from 18 to 36 or alkoxy of 1 to 4 carbon atoms, and
- R" is hydrogen, alkyl of 1 to 4 carbon atoms, halo of atomic weight of from 18 to 36 or alkoxy of 1 to 4 carbon atoms.
- 2. A method in accordance with claim 1 in which the compound is administered in a daily amount of from 200 to 3000 milligrams.
- 3. A method in accordance with claim 1 in which the compound administered is a compound in which R, R' and R" are hydrogen.
- 4. A method in accordance with claim 3 in which the compound administered is .alpha.-tert.-butyl-p-phenoxy benzyl alcohol.
- 5. A pharmaceutical composition in unit dosage form for treating lipidemia in mammals comprising an inert pharmaceutically acceptable carrier and from 50 to 1500 milligrams of a compound of the formula ##STR10## wherein R.degree. is branched alkyl of 3 to 5 carbon atoms,
- R is hydrogen, alkyl of 1 to 4 carbon atoms or halo of atomic weight of from 18 to 36,
- n is 1 or 2,
- R'is hydrogen, alkyl of 1 to 4 carbon atoms, halo of atomic weight of from 18 to 36 or alkoxy of 1 to 4 carbon atoms, and
- R" is hydrogen, alkyl of 1 to 4 carbon atoms, halo of atomic weight of from 18 to 36 or alkoxy of 1 to 4 carbon atoms.
- 6. A composition in accordance with claim 5 wherein the compound is one wherein R, R' and R" are hydrogen.
- 7. A composition in accordance with claim 6 in which the compound is .alpha.-tert.-butyl-p-phenoxy benzyl alcohol.
Parent Case Info
This is a division of application Ser. No. 662,125, filed Feb. 27, 1976, now issued as U.S. Pat. No. 4,085,149, which in turn is a division of application Ser. No. 510,477, filed Sept. 30, 1974, now issued as U.S. Pat. No. 3,962,459, which in turn is a continuation-in-part of Ser. No. 394,181, filed Sept. 4, 1973, now abandoned.
US Referenced Citations (4)
Non-Patent Literature Citations (2)
Entry |
Mowry, JACS, vol. 68, 1946, pp. 1105-1109. |
Farnum, Proc. N. Dak. Acad. Sci., vol. 20, 1966, pp. 78-81. |
Divisions (2)
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Number |
Date |
Country |
Parent |
662125 |
Feb 1976 |
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Parent |
510477 |
Sep 1974 |
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Continuation in Parts (1)
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Number |
Date |
Country |
Parent |
394181 |
Sep 1973 |
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