Claims
- 1. A compound of the formula ##STR3##wherein: the R.sub.2 NCXNR group is at the para or meta position;
- R is hydrogen or lower alkyl of 1-4 carbon atoms;
- X is oxygen or sulfur; and
- A is hydrogen, or acetoxy;
- or a non-toxic pharmaceutically acceptable salt thereof.
- 2. A compound as claimed in claim 1 where the R.sub.2 NCXNR group is at the meta position.
- 3. A compound as claimed in claim 1 where the R.sub.2 NCXNR group is at the para position.
- 4. A compound as claimed in claim 3 where X is oxygen.
- 5. A compound as claimed in claim 4 being the compound 3-methyl-7-(.alpha.-amino-p-ureidophenylacetamido)-3-cephem-4-carboxylic acid.
- 6. A compound as claimed in claim 2 being the compound 3-methyl-7-(.alpha.-amino-m-ureidophenylacetamido)-3-cephem-4-carboxylic acid.
- 7. A compound as claimed in claim 1 where X is sulfur.
- 8. A compound as claimed in claim 7 where R is hydrogen.
- 9. A compound as claimed in claim 4 where each R is hydrogen or methyl.
- 10. A compound as claimed in claim 9 being the compound 3-acetoxymethyl-7-(.alpha.-amino-p-ureidophenylacetamido)-3-cephem-4-carboxylic acid.
- 11. A compound as claimed in claim 2 where X is oxygen and each R is hydrogen or methyl.
- 12. A compound as claimed in claim 11 being the compound 3-acetoxymethyl-7-(.alpha.-amino-m-ureidophenylacetamido)-3-cephem-4-carboxylic acid.
- 13. A compound as claimed in claim 8 being the compound 3-methyl-7-(.alpha.-amino-p-thioureidophenylacetamido)-3-cephem-4-carboxylic acid.
- 14. A compound as claimed in claim 8 being the compound 3-acetoxymethyl-7-(.alpha.-amino-p-thioureidophenylacetamido)-3-cephem-4-carboxylic acid.
- 15. An antibacterially effective pharmaceutical composition comprising a compound as claimed in claim 1 and a pharmaceutically acceptable carrier therefore.
Parent Case Info
This is a division of application Ser. No. 357,763 filed May 7, 1973, now U.S. Pat. No. 4,067,173.
US Referenced Citations (3)
Number |
Name |
Date |
Kind |
3341531 |
Lewis et al. |
Sep 1967 |
|
3464985 |
Holdrege |
Sep 1969 |
|
3573295 |
Johnson et al. |
Mar 1971 |
|
Divisions (1)
|
Number |
Date |
Country |
Parent |
357763 |
May 1973 |
|