Claims
- 1. A compound having the formula ##STR6## wherein: R is hydrogen, a straight or branched-chain alkyl group containing from 1 to 18 carbon atoms, or benzyl;
- Q is methyl or chlorine;
- y is an integer 0 to 4;
- A is an anion;
- m is 1 or 3;
- n is 1 or 2; and
- x is 1, 2 or 3; and,
- wherein (m) (2)=(n) (x).
- 2. A compound having the formula ##STR7## wherein: R is hydrogen, a straight or branched-chain alkyl group containing from 1 to 18 carbon atoms, or benzyl;
- Q is methyl;
- y is an integer 0 to 4;
- A is an anion;
- m is 1 or 3;
- n is 1 or 2; and
- x is 1, 2 or 3; and,
- wherein (m) (2)=(n) (x).
- 3. A compound according to claim 2 where R is hydrogen.
- 4. A compound according to claim 2 wherein R is a straight or branched-chain alkyl group containing from 6 to 12 carbon atoms.
- 5. A compound according to claim 3 wherein the (Q).sub.y -xylylene group linking the 4-(R-amino)-1-pyridinium groups is (Q).sub.y -p-xylylene
- 6. A compound according to claim 4 wherein the (Q).sub.y -xylylene group linking the 4-(R-amino)-1-pyridinium groups is (Q).sub.y -p-xylylene.
- 7. A compound having the formula ##STR8## wherein: R is hydrogen, a straight or branched-chain alkyl group containing from 1 to 18 carbon atoms, or benzyl;
- Q is chlorine;
- y is an integer 1 to 4;
- A is an anion;
- m is 1 or 3;
- n is 1 or 2; and
- x is 1, 2 or 3; and,
- wherein (m) (2)=(n) (x).
- 8. A compound according to claim 7 wherein R is a straight or branched-chain alkyl group containing from 6 to 12 carbon atoms.
- 9. .alpha.,.alpha.'-Bis-(4-amino-1-pyridinium)-p-xylene dichloride according to claim 5.
- 10. .alpha.,.alpha.'-Bis-(4-amino-1-pyridinium)-2,3,5,6-tetramethyl-p-xylene dichloride according to claim 5.
- 11. .alpha.,.alpha.'-Bis-[4-(hexylamino)-1-pyridinium]-p-xylene dibromide according to claim 6.
- 12. .alpha.,.alpha.'-Bis-[4-(heptylamino)-1-pyridinium]-p-xylene dibromide according to claim 6.
- 13. An antibacterial and antifungal composition suitable for topical administration comprising an effective amount of a compound according to claim 1 wherein A is a pharmaceutically acceptable anion, and a pharmaceutically acceptable carrier.
- 14. A skin-cleansing composition comprising an antibacterially and antifungally effective amount of a compound according to claim 1 wherein A is a pharmaceutically acceptable anion, a compatible pharmaceutically acceptable surfactant and a compatible pharmaceutically acceptable diluent or carrier.
- 15. A skin-cleansing composition comprising an antibacterially and antifungally effective amount of a compound according to claim 6 wherein A is a pharmaceutically acceptable anion, a compatible pharmaceutically acceptable surfactant and a compatible pharmaceutically acceptable diluent
- 16. An antibacterial and antifungal composition suitable for application to inanimate surfaces comprising an effective amount of a compound according to claim 1 in combination with a compatible vehicle.
- 17. A method for controlling bacteria and fungi on human skin or other tissues or inanimate surfaces which comprises contacting said bacteria and fungi with an antibacterially and antifungally effective amount of a compound according to claim 1 wherein A is a pharaceutically acceptable anion when said compound is applied to human skin or other tissues.
- 18. A method for controlling bacteria and fungi on human skin or other tissue or inanimate surfaces which comprises contacting said bacteria and fungi with an antibacterially and antifungally effective amount of a compound according to claim 6 wherein A is a pharmaceutically acceptable anion when said compound is applied to human skin or other tissues.
CROSS-REFERENCE TO RELATED APPLICATIONS
This application is a continuation-in-part of prior copending application Ser. No. 661,128, filed Feb. 25, 1976 and now abandoned.
US Referenced Citations (1)
Number |
Name |
Date |
Kind |
3516782 |
Sello et al. |
Jun 1970 |
|
Non-Patent Literature Citations (2)
Entry |
Walker et al., J. Org. Chem., vol. 26, pp. 2740 to 2747 (1961). |
Austin et al., J. Pharm. Pharmacol. vol. 11, pp. 80 to 93 (1959). |
Continuation in Parts (1)
|
Number |
Date |
Country |
Parent |
661128 |
Feb 1976 |
|