Claims
- 1. A purified variant protein of SEQ ID NO: 2 which is at least 70% identical, but not 100% identical to SEQ ID NO: 2 and which catalyze removal of arginine, phenylalanine or methionine from the N-terminal end of peptides in peptide or peptidomimetic synthesis.
- 2. The purified protein of claim 1, wherein the variants are at least about 90% identical to SEQ ID NO:2.
- 3. The purified protein of claim 1, wherein the variants are at least about 95% identical to SEQ ID NO:2.
- 4. The purified protein of claim 1, which comprises at least 30 contiguous amino acid residues.
- 5. A method for removal of arginine, phenylalanine or methionine from the N-terminal end of peptides in peptide or peptidomimetic synthesis, comprising:
- contacting the peptides with an amount of an enzyme of claim 1 effective for removal of arginine, phenylalanine or methionine from the N-terminal end of peptides in peptide or peptidomimetic synthesis.
Parent Case Info
This is a divisional of application Ser. No. 08/664,646, filed Jun. 17, 1996 now U.S. Pat. No. 5,877,001.
US Referenced Citations (3)
Number |
Name |
Date |
Kind |
5190875 |
Steinke et al. |
Mar 1993 |
|
5451522 |
Queener et al. |
Sep 1995 |
|
5494796 |
Spears et al. |
Feb 1996 |
|
Divisions (1)
|
Number |
Date |
Country |
Parent |
664646 |
Jun 1996 |
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