AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND USE OF THE AMIDE DERIVATIVE

Abstract
An amide derivative represented by the following Formula (1) is provided as an amide derivative showing a significantly excellent effect for a pest control action.
Description
BACKGROUND OF THE INVENTION
Field of the Invention

The present invention relates to a pest control agent, an amide derivative contained in the pest control agent, and a method for using the amide derivative.


Description of the Related Art

Various amide derivatives are described in the pamphlets of International Publication WO 2005/21488, International Publication WO 2005/73165, International Publication WO 2006/137376, and International Publication WO 2006/137395.


SUMMARY OF THE INVENTION

In the production of, for example, agricultural and horticultural crops, due to causes such as currently-occurring large scale damage due to pests or the like and the propagation of pests having resistance to existing chemicals, there is a demand for a novel agricultural/horticultural pest control agent.


It is an object of the present invention to provide an amide derivative showing a pesticidal effect against a wide range of agricultural/horticultural pests, a pest control agent containing the amide derivative as an active ingredient, and a pest controlling method.


The present inventors have conducted intensive studies to develop a novle pest control agent, and as a result, they have found that the aromatic carboxamide derivative represented by Formula (1) of the present invention is a novel compound unknown in the literature, and it is also a pest control agent, particularly an agricultural/horticultural pest control agent, showing a particularly high efficiency, thereby completing the present invention.


Further, they have also discovered a novel preparation method and a useful intermediate for the preparation of the compound of the present invention. As a result, they have completed the present invention.


That is, the present invention is as follows.


<1> An amide derivative represented by the following Formula (1):


1. An amide derivative represented by the following Formula (1):




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Wherein, in Formula (1), A represents a carbon atom, an oxygen atom, a nitrogen atom, an oxidized nitrogen atom, or a sulfur atom. K represents a non-metal atom group necessary for forming a cyclic linking group derived from benzene, pyridine, pyridine-N-oxide, pyrimidine, pyrazine, pyridazine, triazine, pyrrole, pyrazole, imidazole, oxazole, isoxazole, thiazole, isothiazole, furan, thiophene, oxadiazole, thiodiazole, or triazole, in combination with A and two carbon atoms to which A bonds.


X represents a hydrogen atom, a halogen atom, a C1-C6 alkyl group, a C1-C6 haloalkyl group, a C3-C9 cycloalkyl group, a C3-C9 halocycloalkyl group, a C2-C6 alkenyl group, a C2-C6 haloalkenyl group, a C2-C6 alkynyl group, a C2-C6 haloalkynyl group, a C1-C6 alkoxy group, a C1-C6 haloalkoxy group, a C2-C6 alkenyloxy group, a C2-C6 haloalkenyloxy group, a C2-C6 alkynyloxy group, a C2-C6 haloalkynyloxy group, a C3-C9 cycloalkoxy group, a C3-C9 halocycloalkoxy group, a C1-C6 alkylthio group, a C1-C6 haloalkylthio group, a C1-C6 alkylsulfinyl group, a C1-C6 haloalkylsulfinyl group, a C1-C6 alkylsulfonyl group, a C1-C6 haloalkylsulfonyl group, a C1-C6 alkylsulfonyloxy group, a C1-C6 haloalkylsulfonyloxy group, a C2-C7 alkylcarbonyl group, a C2-C7 haloalkylcarbonyl group, a C3-C7 alkenylcarbonyl group, a C3-C7 haloalkenylcarbonyl group, a C3-C7 alkynylcarbonyl group, a C3-C7 haloalkynylcarbonyl group, a C4-C10 cycloalkylcarbonyl group, a C4-C10 halocycloalkylcarbonyl group, a C2-C7 alkylcarbonyloxy group, a C2-C7 haloalkylcarbonyloxy group, arylcarbonyloxy group, a C2-C7 alkoxycarbonyl group, a C2-C7 haloalkoxycarbonyl group, a C3-C7 alkenyloxycarbonyl group, a C3-C7 haloalkenyloxycarbonyl group, a C3-C7 alkynyloxycarbonyl group, a C3-C7 haloalkynyloxycarbonyl group, a C4-C10 cycloalkyloxycarbonyl group, a C4-C10 halocycloalkyloxycarbonyl group, a C2-C7 alkylcarbonylamino group, a C2-C7 haloalkylcarbonylamino group, a C2-C7 alkoxycarbonylamino group, a C2-C7 haloalkoxycarbonylamino group, a C2-C7 alkoxycarbonyloxy group, a C2-C7 haloalkoxycarbonyloxy group, an arylcarbonylamino group, an amino group, a carbamoyl group, a cyano group, a hydroxy group, pentafluorosulfanyl group, a C1-C6 alkylamino group, a C1-C6 haloalkylamino group, a C2-C6 alkenylamino group, a C2-C6 haloalkenylamino group, a C2-C6 alkynylamino group, a C2-C6 haloalkynylamino group, a C3-C9 cycloalkylamino group, a C3-C9 halocycloalkylamino group, a C2-C7 alkylaminocarbonyl group, a C2-C7 haloalkylaminocarbonyl group, a C3-C7 alkenylaminocarbonyl group, a C3-C7 haloalkenylaminocarbonyl group, a C3-C7 alkypylaminocarbonyl group, a C3-C7 haloalkynylaminocarbonyl group, a C4-C10 cycloalkylaminocarbonyl group, a C4-C10 halocycloalkylaminocarbonyl group, a phenyl group, or a heterocyclic group, and when there are plural X's, each X may be the same as or different from an other.


n represents an integer of from 0 to 4.


T represents —C(=G1)-Q1 or —C(=G1)-G2Q2.


G1 and G2 each independently represent an oxygen atom or a sulfur atom,


Q1 and Q2 each represent a hydrogen atom, a C1-C6 alkyl group, a C1-C6 haloalkyl group, a C2-C6 alkenyl group, a C2-C6 haloalkenyl group, a C2-C6 alkynyl group, a C2-C6 haloalkynyl group, a C3-C9 cycloalkyl group, a C3-C9 halocycloalkyl group, a benzyl group, a phenyl group which may have a substituent, a naphthyl group, or a heterocyclic group which may have a substituent.


Y1 and Y5 each independently represent a halogen atom, a C1-C6 haloalkoxy group, or a C1-C3 haloalkyl group, Y2 and Y4 each independently represent a hydrogen atom, a halogen atom, or a C1-C4 alkyl group, Y3 represents a C2-C5 haloalkyl group.


Wherein in Q1 and Q2, the substituent of a phenyl group which may have a substituent and a heterocyclic group which may have a substituent represents one or more substituent selected from a group consisting of a halogen atom, a C1-C6 alkyl group, a C1-C6 haloalkyl group, a C3-C9 cycloalkyl group, a C3-C9 halocycloalkyl group, a C2-C6 alkenyl group, a C2-C6 haloalkenyl group, a C2-C6 alkynyl group, a C2-C6 haloalkynyl group, a C1-C6 alkoxy group, a C1-C6 haloalkoxy group, a C2-C6 alkenyloxy group, a C2-C6 haloalkenyloxy group, a C2-C6 alkynyloxy group, a C2-C6 haloalkynyloxy group, a C3-C9 cycloalkoxy group, a C3-C9 halocycloalkoxy group, a C1-C6 alkylthio group, a C1-C6 haloalkylthio group, a C1-C6 alkylsulfinyl group, a C1-C6 haloalkylsulfinyl group, a C1-C6 alkylsulfonyl group, a C1-C6 haloalkylsulfonyl group, a C2-C7 alkylcarbonyl group, a C2-C7 haloalkylcarbonyl group, a C3-C7 alkenylcarbonyl group, a C3-C7 haloalkenylcarbonyl group, a C3-C7 alkynylcarbonyl group, a C3-C7 haloalkynylcarbonyl group, a C4-C10 cycloalkylcarbonyl group, a C4-C10 halocycloalkylcarbonyl group, a C2-C7 alkylcarbonyloxy group, a C2-C7 haloalkylcarbonyloxy group, a C1-C6 alkylsulfonyloxy group, a C1-C6 haloalkylsulfonyloxy group, a C2-C7 alkoxycarbonyl group, a C2-C7 haloalkoxycarbonyl group, a C3-C7 alkenyloxycarbonyl group, a C3-C7 haloalkenyloxycarbonyl group, a C3-C7 alkynyloxycarbonyl group, a C3-C7 haloalkynyloxycarbonyl group, a C4-C10 cycloalkyloxycarbonyl group, a C4-C10 halocycloalkyloxycarbonyl group, a C2-C7 alkylcarbonylamino group, a C2-C7 haloalkylcarbonylamino group, a C2-C7 alkoxycarbonylamino group, a C2-C7 haloalkoxycarbonylamino group, a C1-C6 alkylamino group, a C1-C6 haloalkylamino group, a C2-C6 alkenylamino group, a C2-C6 haloalkenylamino group, a C2-C6 alkynylamino group, a C2-C6 haloalkynylamino group, a C3-C9 cycloalkylamino group, a C3-C9 halocycloalkylamino group, a C2-C7 alkylaminocarbonyl group, a C2-C7 haloalkylaminocarbonyl group, a C3-C7 alkenylaminocarbonyl group, a C3-C7 haloalkenylaminocarbonyl group, a C3-C7 alkynylaminocarbonyl group, a C3-C7 haloalkynylaminocarbonyl group, a C4-C10 cycloalkylaminocarbonyl group, a C4-C10 halocycloalkylaminocarbonyl group, an amino group, a carbamoyl group, a cyano group, a nitro group, a hydroxy group, pentafluorosulfanyl group, a phenyl group which may have a substituent, and a heterocyclic group which may have a substituent, and when there are two or more substituents, the substituents may be the same as or different from each other.


Wherein the heterocyclic group in X, Q1, and Q2 represent a pyridyl group, a pyridine-N-oxide group, a pyrimidinyl group, a pyrazinyl group, a pyridazyl group, a furyl group, a thienyl group, an oxazolyl group, an isoxazolyl group, an oxadiazolyl group, a thiazolyl group, an isothiazolyl group, a thiadiazolyl group, a pyrrolyl group, an imidazolyl group, a triazolyl group, a pyrazolyl group, or a tetrazolyl group.


G3 represents an oxygen atom or a sulfur atom.


R1 and R2 each independently represent a hydrogen atom, an oxygen atom, a halogen atom, a hydroxy group, a nitro group, a nitroso group, a trimethylsilyl group, a t-butyldimethylsilyl group, a cyano group, an amino group, a C1-C6 alkyl group which may have a substituent, a C1-C6 haloalkyl group which may have a substituent, a C2-C7 alkylcarbonyl group, a C2-C7 haloalkylcarbonyl group, a C2-C6 alkenyl group which may have a substituent, a C2-C6 haloalkenyl group which may have a substituent, a C2-C6 alkynyl group which may have a substituent, a C2-C6 haloalkynyl group which may have a substituent, a C2-C7 alkoxycarbonyl group, a C2-C7 haloalkoxycarbonyl group, a C3-C7 alkenyloxycarbonyl group, a C3-C7 haloalkenyloxycarbonyl group, a C3-C7 alkynyloxycarbonyl group, a C3-C7 haloalkynyloxycarbonyl group, a phenoxycarbonyl group, a C2-C7 alkylaminocarbonyl group, a C2-C7 haloalkylaminocarbonyl group, a C2-C7 alkylcarbonyloxy group, a C2-C7 haloalkylcarbonyloxy group, a benzoyl group, a C1-C6 alkoxy group, a C1-C6 haloalkoxy group, a C1-C6 alkylthio group, a C1-C6 haloalkylthio group, a C1-C6 alkylsulfinyl group, a C1-C6 haloalkylsulfinyl group, a C1-C6 alkylsulfonyl group, a C1-C6 haloalkylsulfonyl group, a benzenesulfonyl group, a benzylsulfonyl group, a benzyl group, or —C(═O)C(═O)R7, wherein R7 represents a C1-C6 alkyl group, a C1-C6 haloalkyl group, a C1-C6 alkoxy group, or a C1-C6 haloalkoxy group.


However the amide derivative represented by Formula (1) is not one of (A) to (I).


(A) A case where, in Formula (1), K represents a non-metal atom group necessary for forming a cyclic linking group derived from pyridine in combination with A and two carbon atoms to which A bonds, Y1 represents a halogen atom, and Y5 represents a C1-C6 haloalkoxy group, and T is —C(=G1)-Q1.


(B) A case where, in Formula (1), K represents a non-metal atom group necessary for forming a cyclic linking group derived from pyrrole, pyrazole, imidazole, oxazole, isoxazole, thiazole, isothiazole, furan, thiophene, oxadiazole, thiodiazole, or triazole, in combination with A and two carbon atoms to which A bonds, Y1 and Y5 represent each independently a halogen atom, and T is —C(=G1)-G2Q2.


(C) A case where, in Formula (1), K represents a non-metal atom group necessary for forming a cyclic linking group derived from pyrrole, pyrazole, imidazole, oxazole, isoxazole, thiazole, isothiazole, furan, thiophene, oxadiazole, thiodiazole, or triazole, in combination with A and two carbon atoms to which A bonds, T represents —C(=G1)-Q1, Y1 is a halogen atom, and Y5 represents a halogen atom or a haloalkoxy group.


(D) A case where, the amide derivative is an amide compound represented by the following Formula (2):




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Wherein in Formula (2), Y2 to Y4, Q1, G1, G3, R1, and R2 have the same definitions as Y2 to Y4, Q1, G1, G3, R1, and R2, respectively, in Formula (1), Y1 represents a halogen atom, and Y5 represents a C1-C2 haloalkoxy group.


(E) A case where, in Formula (2), Y1 and Y5 each independently represent a halogen atom, all X's represent hydrogen atoms, and Y3 represents a C2-C3 haloalkyl group.


(F) A case where, the amide derivative is an amide derivative represented by the following Formula (3)




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Wherein in Formula (3), Y1 and Y5 each independently represent a halogen atom, X1 and X3 each independently represent a hydrogen atom or a fluorine atom, Q1 has the same definition as Q1 in Formula (1), R1 represents a hydrogen atom or a methyl group, and Y3 represents a C3-C4 perfluoroalkyl group.


(G) A case where the amide derivative is an amide derivative represented by the following Formula (4):




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Wherein in Formula (4), X1 represents a fluorine atom, X2, X3, and X4 represent hydrogen atoms, Y1 and Y5 are different from each other and represent a bromine atom or a trifluoromethoxy group, Y2 and Y4 represent hydrogen atoms, Y3 represents a heptafluoroisopropyl group, Q1 represents a phenyl group or a 2-chloropyridin-3-yl group, and R1 and R2 are different from each other, and each represent a hydrogen atom or a methyl group.


Alternatively, X1 represents a fluorine atom, X2, X3, and X4 represent hydrogen atoms, Y1 and Y5 represent bromine atoms, Y2 and Y4 represent hydrogen atoms, Y3 represents a pentafluoroethyl group, Q1 represents a 2-fluorophenyl group, and R1 and R2 each independently represent a hydrogen atom or a methyl group}.


(H) A case where, the amide derivative is an amide derivative represented by the following Formula (5):




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Wherein, in Formula (5), Y1 and Y5 each independently represent a halogen atom, X1 represents a hydrogen atom or a fluorine atom, Q2 represents a 2,2,2-trichloroethyl group or a 3,3,3-trifluoro-n-propyl group, and Y3 represents a C2-C4 haloalkyl group.


(I) A case where the amide derivative is an amide derivative represented by the following Formula (6):




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Wherein, in Formula (6), Y1 and Y5 each independently represent a halogen atom, Q2 has the same definition as Q2 in Formula (1), R1 represents a hydrogen atom or a methyl group, and Y3 represents a C3-C4 haloalkyl group.


<2> The amide compound according to <1>, which is represented by the following Formula (7):




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Wherein, in Formula (7), n represents 4, and X, Y1 to Y5, Q1, G1, G3, R1, and R2 have the same definitions as X, Y1 to Y5, Q1, G1, G3, R1, and R2, respectively, in Formula (1).


<3> The amide derivative according to <2>, which is represented by the following Formula (8):




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Wherein, in Formula (8), Q1 represents a phenyl group which may have a substituent or a pyridyl group which may have a substituent.


X1, X2, X3, and X4 each independently represent a hydrogen atom or a fluorine atom.


R1 and R2 each independently represent a hydrogen atom or a C1-C3 alkyl group.


Y1 and Y5 each independently represent a halogen atom, a C1-C3 haloalkoxy group, or a C1-C3 haloalkyl group, Y2 and Y4 each independently represent a hydrogen atom, a halogen atom, or a C1-C4 alkyl group, and Y3 represents a C3-C4 haloalkyl group.


In a case where Y1 and Y5 represent halogen atoms simultaneously, at least one of X1 and X2 represents a fluorine atom. Further, in a case where Y1 or Y5 represents a C1-C3 haloalkoxy group, X2 represents a fluorine atom.


<4> The amide derivative according to <3>, wherein in Formula (8), Y3 represents a C3-C4 perfluoroalkyl group.


<5> The amide derivative according to <4>, wherein in Formula (8), Y1 and Y5 each independently represent a chlorine atom, a bromine atom, an iodine atom, a trifluoromethoxy group, a trifluoromethyl group, or a pentafluoroethyl group, and Y2 and Y4 represent hydrogen atoms.


<6> The amide derivative according to <5>, wherein in Formula (8), X1 and X2 each independently represent a hydrogen atom or a fluorine atom, and X3 and X4 represent hydrogen atoms.


<7> The amide derivative according to <6>, wherein in Formula (8), R1 and R2 each independently represent a hydrogen atom or a methyl group.


<8> The amide derivative according to claim 7, wherein in Formula (8), Q1 represents a phenyl group or a pyridyl group which may have a substituent selected from a group consisting of a halogen atom, a C1 haloalkyl group, a nitro group, and a cyano group.


<9> The amide derivative according to claim 8, wherein in Formula (8), the number of the substituents in Q1 is 1 or 2.


<10> The amide derivative according to <9>, wherein in Formula (8), Q1 represents a phenyl group, a 2-fluorophenyl group, a 3-fluorophenyl group, a 4-fluorophenyl group, a 2-chlorophenyl group, a 3-chlorophenyl group, a 4-chlorophenyl group, a 2-bromophenyl group, a 3-bromophenyl group, a 4-bromophenyl group, a 2-iodophenyl group, a 3-iodophenyl group, a 4-iodophenyl group, a (2-triofluoromethyl)phenyl group, a (3-triofluoromethyl)phenyl group, a (4-triofluoromethyl)phenyl group, a 2-nitrophenyl group, a 3-nitrophenyl group, a 4-nitrophenyl group, a 2-cyanophenyl group, a 3-cyanophenyl group, a 4-cyanophenyl group, a 2,6-difluorophenyl group, a 3,4-dichlorophenyl group, a 2,4-dichlorophenyl group, a 2-chloro-4-fluorophenyl group, a 2-chloro-4, 5-difluorophenyl group, a 4-bromo-2-chlorophenyl group, a 2-bromo-4-chlorophenyl group, a 2-bromo-4-fluorophenyl group, a 2-chloro-4-nitrophenyl group, a 3, 5-dicyanophenyl group, a 4-cyano-2-fluorophenyl group, a 2-chloro-4-cyanophenyl group, a pyridin-3-yl group, a 2-fluoropyridin-3-yl group, a 2-chloropyridin-3-yl group, a 2-bromopyridin-3-yl group, a 2-iodopyridin-3-yl group, a 2-(trifluoromethyl)pyridin-3-yl group, a 2-nitropyridin-3-yl group, a 2-cyanopyridin-3-yl group, a 6-fluoropyridin-3-yl group, a 6-chloropyridin-3-yl group, a 6-bromopyridin-3-yl group, a 6-iodopyridin-3-yl group, a 6-(trifluoromethyl)pyridin-3-yl group, a 6-nitropyridin-3-yl group, a 6-cyanopyridin-3-yl group, a 5-fluoropyridin-3-yl group, a 5-chloropyridin-3-yl group, a 5-bromopyridin-3-yl group, a 5-iodopyridin-3-yl group, a 5-(trifluoromethyl)pyridin-3-yl group, a 5-nitropyridin-3-yl group, a 5-cyanopyridin-3-yl group, a 4-fluoropyridin-3-yl group, a 4-chloropyridin-3-yl group, a 4-bromopyridin-3-yl group, a 4-iodopyridin-3-yl group, a 4-(trifluoromethyl)pyridin-3-yl group, a 4-nitropyridin-3-yl group, a 4-cyanopyridin-3-yl group, a 2,6-dichloropyridin-3-yl group, a pyridin-3-yl N-oxide group, a pyridin-4-yl group, a 2-chloropyridin-4-yl group, a 3-bromopyridin-4-yl group, a 3,5-dichloropyridin-4-yl group, a 3-(trifluoromethyl)pyridine-4-yl group, a 2,6-dicyanopyridin-4-yl group, a pyridin-4-yl N-oxide group, a pyridin-2-yl group, a 3-chloropyridin-2-yl group, a 4-bromopyridin-2-yl group, a 5-iodopyridin-2-yl group, a 6-chloropyridin-2-yl group, or a 4-cyanopyridin-2-yl group,


<11> The amide derivative according to <10>, wherein the compound represented by Formula (8) is 3-benzamido-N-(2-bromo-6-chloro-4-(perfluoropropan-2-yl)phenyl)-2-fluorobenzamide, 2-chloro-N-(3-(2,6-dibromo-4-(perfluoropropan-2-yl)phenylcarbamoyl)-2-fluorophenyl)nicotinamide, 3-(4-cyano-N-methylbenzamiido)-N-(2,6-dibromo-4-(perfluoropropan-2-yl)phenyl)-2-fluorobenzamide, 2-chloro-N-(3-(2,6-dibromo-4-(perfluoropropan-2-yl)phenylcarbamoyl)-2-fluorophenyl)-N-methylnicotinamide, 3-benzamido-N-(2,6-diiodo-4-(perfluoropropan-2-yl)phenyl)-2-fluorobenzamide, 3-benzamido-N-(2,6-dibromo-4-(perfluoropropan-2-yl)phenyl)-2-fluorobenzamide, N-(2,6-dibromo-4-(perfluoropropan-2-yl)phenyl)-2-fluoro-3-(N-methylbenzamido)benzamide, 6-chloro-N-(3-(2,6-dibromo-4-(perfluoropropan-2-yl)phenylcarbamoyl)-2-fluorophenyl)-N-methylnicotinamide, 3-(3-cyano-N-methylbenzamido)-N-(2,6-dibromo-4-(perfluoropropan-2-yl)phenyl)-2-fluorobenzamide, N-(2,6-dichloro-4-(perfluoropropan-2-yl)phenyl)-2-fluoro-3-(N-methylbenzamido)benzamide, 3-(4-cyano-N-methylbenzamido)-N-(2,6-dichloro-4-(perfluoropropan-2-yl)phenyl)-2-fluorobenzamide, 2-chloro-N-(3-(2,6-dichloro-4-(perfluoropropan-2-yl)phenylcarbamoyl)-2-fluorophenyl)-N-methylnicotinamide, N-(2,6-diiodo-4-(perfluoropropan-2-yl)phenyl)-2-fluoro-3-(N-methylbenzamiido)benzamide, 3-(4-cyano-N-methylbenzamido)-N-(2,6-diiodo-4-(perfluoropropan-2-yl)phenyl)-2-fluorobenzamide, 3-benzamido-N-(2,6-dibromo-4-(perfluorobutan-2-yl)phenyl)-2-fluorobenzamide, N-(2,6-diiodo-4-(perfluoropropan-2-yl)phenyl)-2-fluoro-3-(2-fluorobenzamido)benzamide, N-(2,6-diiodo-4-(perfluoropropan-2-yl)phenyl)-2-fluoro-3-(4-fluorobenzamido)benzamide, 3-(2,6-difluorobenzamido)-N-(2,6-diiodo-4-(perfluoropropan-2-yl)phenyl)-2-fluorobenzamide, N-(2-bromo-6-iodo-4-(perfluoropropan-2-yl)phenyl)-2-fluoro-3-(N-methylbenzamido)benzamide, N-(3-(2-bromo-6-iodo-4-(perfluoropropan-2-yl)phenylcarbamoyl)-2-fluorophenyl)-2-chloro-N-methylnicotinamide,


3-(4-cyanobenzamido)-N-(2,6-dibromo-4-(perfluorobutan-2-yl)phenyl)-2-fluorobenzamide, 3-(3-cyanobenzamido)-N-(2,6-dibromo-4-(perfluorobutan-2-yl)phenyl)-2-fluorobenzamide, N-(2,6-dibromo-4-(perfluorobutan-2-yl)phenyl)-2-fluoro-3-(N-methylbenzamido)benzamide, 3-(4-cyano-N-methylbenzamido)-N-(2,6-dibromo-4-(perfluorobutan-2-yl)phenyl)-2-fluorobenzamide, 3-(3-cyano-N-methylbenzamido)-N-(2,6-dibromo-4-(perfluorobutan-2-yl)phenyl)-2-fluorobenzamide, 6-chloro-N-(3-(2,6-dibromo-4-(perfluorobutan-2-yl)phenylcarbamoyl)-2-fluorophenyl)-N-methylnicotinamide, 3-benzamido-N-(2,6-diiodo-4-(perfluorobutan-2-yl)phenyl)-2-fluorobenzamide, 3-(3-cyanobenzamido)-N-(2,6-diiodo-4-(perfluorobutan-2-yl)phenyl)-2-fluorobenzamide, 3-(4-cyanobenzamido)-N-(2,6-diiodo-4-(perfluorobutan-2-yl)phenyl)-2-fluorobenzamide, N-(2,6-diiodo-4-(perfluorobutan-2-yl)phenyl)-2-fluoro-3-(N-methylbenzamido)benzamide, 3-(3-cyano-N-methylbenzamido)-N-(2,6-diiodo-4-(perfluorobutan-2-yl)phenyl)-2-fluorobenzamide, 3-(4-cyano-N-methylbenzamiido)-N-(2,6-diiodo-4-(perfluorobutan-2-yl)phenyl)-2-fluorobenzamide, 3-benzamido-N-(2,6-diiodo-4-(perfluorobutan-2-yl)phenyl)benzamide, 2-chloro-N-(3-(2,6-diiodo-4-(perfluorobutan-2-yl)phenylcarbamoyl)phenyl)nicotinamide, 6-chloro-N-(3-(2,6-diiodo-4-(perfluorobutan-2-yl)phenylcarbamoyl)phenyl)nicotinamide, 3-cyano-N-(3-(2,6-diiodo-4-(perfluorobutan-2-yl)phenylcarbamoyl)phenyl)benzamide, 3-(4-cyanobenzamido)-N-(2,6-diiodo-4-(perfluorobutan-2-yl)phenyl)benzamide, N-(3-(2,6-diiodo-4-(perfluorobutan-2-yl)phenylcarbamoyl)phenyl)-2-fluorobenzamide, N-(2,6-diiodo-4-(perfluorobutan-2-yl)phenyl)-3-(3-fluorobenzamido)benzamide, N-(2,6-diiodo-4-(perfluorobutan-2-yl)phenyl)-3-(4-fluorobenzamido)benzamide,


N-(3-(2,6-diiodo-4-(perfluorobutan-2-yl)phenylcarbamoyl)phenyl)-2,6-difluorobenzamide, N-(3-(2,6-diiodo-4-(perfluorobutan-2-yl)phenylcarbamoyl)phenyl)-N-methylbenzamide, 2-chloro-N-(3-(2,6-diiodo-4-(perfluorobutan-2-yl)phenylcarbamoyl)phenyl)-N-methylnicotinamide, 6-chloro-N-(3-(2,6-diiodo-4-(perfluorobutan-2-yl)phenylcarbamoyl)phenyl)-N-methylnicotinamide, 3-cyano-N-(3-(2,6-diiodo-4-(perfluorobutan-2-yl)phenylcarbamoyl)phenyl)-N-methylbenzamide, 4-cyano-N-(3-(2,6-diiodo-4-(perfluorobutan-2-yl)phenylcarbamoyl)phenyl)-N-methylbenzamide, N-(3-(2,6-diiodo-4-(perfluorobutan-2-yl)phenylcarbamoyl)phenyl)-2-fluoro-N-methylbenzamide, N-(3-(2,6-diiodo-4-(perfluorobutan-2-yl)phenylcarbamoyl)phenyl)-3-fluoro-N-methylbenzamide, N-(3-(2,6-diiodo-4-(perfluorobutan-2-yl)phenylcarbamoyl)phenyl)-4-fluoro-N-methylbenzamide, N-(3-(2,6-diiodo-4-(perfluorobutan-2-yl)phenylcarbamoyl)phenyl)-2,6-difluoro-N-methylbenzamide, 2-chloro-N-(3-(2,6-diiodo-4-(perfluorobutan-2-yl)phenylcarbamoyl)-2-fluorophenyl)nicotinamide, 6-chloro-N-(3-(2,6-diiodo-4-(perfluorobutan-2-yl)phenylcarbamoyl)-2-fluorophenyl)nicotinamide, N-(2,6-diiodo-4-(perfluorobutan-2-yl)phenyl)-2-fluoro-3-(2-fluorobenzamido)benzamide, N-(2,6-diiodo-4-(perfluorobutan-2-yl)phenyl)-2-fluoro-3-(3-fluorobenzamido)benzamide, N-(2,6-diiodo-4-(perfluorobutan-2-yl)phenyl)-2-fluoro-3-(4-fluorobenzamido)benzamide, 3-(2,6-difluorobenzamido)-N-(2,6-d iodo-4-(perfluorobutan-2-yl)phenyl)-2-fluorobenzamide, 3-benzamido-N-(2,6-dibromo-4-(perfluorobutan-2-yl)phenyl)benzamide, 6-chloro-N-(3-(2,6-dibromo-4-(perfluorobutan-2-yl)phenylcarbamoyl)phenyl)nicotinamide, N-(3-(2,6-dibromo-4-(perfluorobutan-2-yl)phenylcarbamoyl)phenyl)-2-fluorobenzamide, 2-chloro-N-(3-(2,6-dibromo-4-(perfluorobutan-2-yl)phenylcarbamoyl)phenyl)nicotinamide,


N-(2,6-dibromo-4-(perfluorobutan-2-yl)phenyl)-3-(3-fluorobenzamido)benzamide, N-(2,6-dibromo-4-(perfluorobutan-2-yl)phenyl)-3-(4-fluorobenzamido)benzamide, N-(3-(2,6-dibromo-4-(perfluorobutan-2-yl)phenylcarbamoyl)phenyl)-2,6-difluorobenzamide, 3-cyano-N-(3-(2,6-dibromo-4-(perfluorobutan-2-yl)phenylcarbamoyl)phenyl)benzamide, 3-(4-cyanobenzamido)-N-(2,6-dibromo-4-(perfluorobutan-2-yl)phenyl)benzamide, 2-chloro-N-(3-(2,6-diiodo-4-(perfluorobutan-2-yl)phenylcarbamoyl)-2-fluorophenyl)-N-methylnicotinamide, 6-chloro-N-(3-(2,6-diiodo-4-(perfluorobutan-2-yl)phenylcarbamoyl)-2-fluorophenyl)-N-methylnicotinamide, N-(3-(2,6-diiodo-4-(perfluorobutan-2-yl)phenylcarbamoyl)-2-fluorophenyl)-2-fluoro-N-methylbenzamide, N-(2,6-diiodo-4-(perfluorobutan-2-yl)phenyl)-2-fluoro-3-(3-fluoro-N-methylbenzamido)benzamide, N-(2,6-diiodo-4-(perfluorobutan-2-yl)phenyl)-2-fluoro-3-(4-fluoro-N-methylbenzamido)benzamide, N-(3-(2,6-diiodo-4-(perfluorobutan-2-yl)phenylcarbamoyl)-2-fluorophenyl)-2,6-difluoro-N-methylbenzamide, N-(3-(2,6-dibromo-4-(perfluorobutan-2-yl)phenylcarbamoyl)phenyl)-N-methylbenzamide, 2-chloro-N-(3-(2,6-dibromo-4-(perfluorobutan-2-yl)phenylcarbamoyl)phenyl)-N-methylnicotinamide, 6-chloro-N-(3-(2,6-dibromo-4-(perfluorobutan-2-yl)phenylcarbamoyl)phenyl)-N-methylnicotinamide, 3-cyano-N-(3-(2,6-dibromo-4-(perfluorobutan-2-yl)phenylcarbamoyl)phenyl)-N-methylbenzamide, 4-cyano-N-(3-(2,6-dibromo-4-(perfluorobutan-2-yl)phenylcarbamoyl)phenyl)-N-methylbenzamide, N-(3-(2,6-dibromo-4-(perfluorobutan-2-yl)phenylcarbamoyl)phenyl)-2-fluoro-N-methylbenzamide, N-(3-(2,6-dibromo-4-(perfluorobutan-2-yl)phenylcarbamoyl)phenyl)-3-fluoro-N-methylbenzamide, N-(3-(2,6-dibromo-4-(perfluorobutan-2-yl)phenylcarbamoyl)phenyl)-4-fluoro-N-methylbenzamide, N-(3-(2,6-dibromo-4-(perfluorobutan-2-yl)phenylcarbamoyl)phenyl)-2,6-difluoro-N-methylbenzamide,


2-chloro-N-(3-(2,6-dibromo-4-(perfluorobutan-2-yl)phenylcarbamoyl)-2-fluorophenyl)nicotinamide, 6-chloro-N-(3-(2,6-dibromo-4-(perfluorobutan-2-yl)phenylcarbamoyl)-2-fluorophenyl)nicotinamide, N-(2,6-dibromo-4-(perfluorobutan-2-yl)phenyl)-2-fluoro-3-(2-fluorobenzamido)benzamide, N-(2,6-dibromo-4-(perfluorobutan-2-yl)phenyl)-2-fluoro-3-(3-fluorobenzamido)benzamide, N-(2,6-dibromo-4-(perfluorobutan-2-yl)phenyl)-2-fluoro-3-(4-fluorobenzamido)benzamide, N-(2,6-dibromo-4-(perfluorobutan-2-yl)phenyl)-3-(2,6-difluorobenzamido)-2-fluorobenzamide, 2-chloro-N-(3-(2,6-diiodo-4-(perfluoropropan-2-yl)phenylcarbamoyl)-2-fluorophenyl)nicotinamide, 6-chloro-N-(3-(2,6-diiodo-4-(perfluoropropan-2-yl)phenylcarbamoyl)-2-fluorophenyl)nicotinamide, 3-(3-cyanobenzamido)-N-(2,6-diiodo-4-(perfluoropropan-2-yl)phenyl)-2-fluorobenzamide, 3-(4-cyanobenzamido)-N-(2,6-diiodo-4-(perfluoropropan-2-yl)phenyl)-2-fluorobenzamide, N-(2,6-diiodo-4-(perfluoropropan-2-yl)phenyl)-2-fluoro-3-(3-fluorobenzamido)benzamide, 2-chloro-N-(3-(2,6-dibromo-4-(perfluorobutan-2-yl)phenylcarbamoyl)-2-fluorophenyl)-N-methylnicotinamide, N-(3-(2,6-dibromo-4-(perfluorobutan-2-yl)phenylcarbamoyl)-2-fluorophenyl)-2-fluoro-N-methylbenzamide, N-(2,6-dibromo-4-(perfluorobutan-2-yl)phenyl)-2-fluoro-3-(3-fluoro-N-methylbenzamido)benzamide, N-(2,6-dibromo-4-(perfluorobutan-2-yl)phenyl)-2-fluoro-3-(4-fluoro-N-methylbenzamido)benzamide, N-(3-(2,6-dibromo-4-(perfluorobutan-2-yl)phenylcarbamoyl)-2-fluorophenyl)-2,6-difluoro-N-methylbenzamide, 3-(3-cyano-N-methylbenzamido)-N-(2,6-diiodo-4-(perfluoropropan-2-yl)phenyl)-2-fluorobenzamide, N-(3-(2,6-diiodo-4-(perfluoropropan-2-yl)phenylcarbamoyl)-2-fluorophenyl)-2-fluoro-N-methylbenzamide, N-(2,6-diiodo-4-(perfluoropropan-2-yl)phenyl)-2-fluoro-3-(3-fluoro-N-methylbenzamido)benzamide, 6-chloro-N-(3-(2,6-diiodo-4-(perfluoropropan-2-yl)phenylcarbamoyl)-2-fluorophenyl)-N-methylnicotinamide,


N-(2,6-diiodo-4-(perfluoropropan-2-yl)phenyl)-2-fluoro-3-(4-fluoro-N-methylbenzamido)benzamide, N-(3-(2,6-diiodo-4-(perfluoropropan-2-yl)phenylcarbamoyl)-2-fluorophenyl)-2,6-difluoro-N-methylbenzamide, N-(2,6-dibromo-4-(perfluoropropan-2-yl)phenyl)-2-fluoro-3-(2-fluorobenzamido)benzamide, N-(2,6-dibromo-4-(perfluoropropan-2-yl)phenyl)-2-fluoro-3-(3-fluorobenzamido)benzamide, N-(2,6-dibromo-4-(perfluoropropan-2-yl)phenyl)-2-fluoro-3-(4-fluorobenzamido)benzamide, N-(2,6-dibromo-4-(perfluoropropan-2-yl)phenyl)-3-(2,6-difluorobenzamido)-2-fluorobenzamide, 6-chloro-N-3-(2,6-dibromo-4-(perfluoropropan-2-yl)phenylcarbamoyl)-2-fluorophenyl)nicotinamide, 3-(3-cyanobenzamido)-N-(2,6-dibromo-4-(perfluoropropan-2-yl)phenyl)-2-fluorobenzamide, 3-(4-cyanobenzamido)-N-(2,6-dibromo-4-(perfluoropropan-2-yl)phenyl)-2-fluorobenzamide, 2-chloro-N-(3-(2,6-diiodo-4-(perfluoropropan-2-yl)phenylcarbamoyl)-2-fluorophenyl)-N-methylnicotinamide, N-(3-(2,6-dibromo-4-(perfluoropropan-2-yl)phenylcarbamoyl)-2-fluorophenyl)-2-fluoro-N-methylbenzamide, N-(2,6-dibromo-4-(perfluoropropan-2-yl)phenyl)-2-fluoro-3-(3-fluoro-N-methylbenzamido)benzamide, N-(2,6-dibromo-4-(perfluoropropan-2-yl)phenyl)-2-fluoro-3-(4-fluoro-N-methylbenzamido)benzamide, N-(3-(2,6-dibromo-4-(perfluoropropan-2-yl)phenylcarbamoyl)-2-fluorophenyl)-2,6-difluoro-N-methylbenzamide, 3-benzamido-N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethoxy)phenyl)-2-fluorobenzamide, N-(3-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethoxy)phenylcarbamoyl)-2-fluorophenyl)-2-chloronicotinamide, N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethoxy)phenyl)-3-(4-cyanobenzamido)-2-fluorobenzamide, 3-benzamido-N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)benzamide, N-(3-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-2-chloronicotinamide, N-(3-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-N-methylbenzamide, N-(3-(2-bromo-4-(perfluoropropan-2-yl)-6-trifluoromethyl)phenylcarbamoyl)phenyl)-2-chloro-N-methylnicotinamide, 3-benzamido-N-(2-chloro-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)benzamide, 2-chloro-N-(3-(2-chloro-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)nicotinamide, N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-3-(3-cyanobenzamido)benzamide,


N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-3-(4-cyanobenzamido)benzamide, N-(3-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-3-cyano-N-methylbenzamide, N-(3-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-4-cyano-N-methylbenzamide, N-(3-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-2-fluoro-N-methylnicotinamide, N-(3-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-N-methyl-4-nitrobenzamide, N-(3-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-6-chloro-N-methylnicotinamide, N-(3-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-6-cyano-N-methylnicotinamide, N-(3-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-N-methyl-3-nitrobenzamide, N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-N-methyl-3-(N-methylbenzamido)benzamide, N-(3-((2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)(methyl)carbamoyl)phenyl)-2-chloro-N-methylnicotinamide, 2-bromo-N-(3-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)nicotinamide, 2-chloro-N-(3-(2-chloro-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-N-methylnicotinamide, N-(3-(2-chloro-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-4 cyano-N-methylbenzamide, 3-benzamido-N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-4-fluorobenzamide, N-(5-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)-2-fluorophenyl)-2-chloronicotinamide, N-(3-((2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)(methyl)carbamoyl)phenyl)-2-chloronicotinamide, N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-4-fluoro-3-(N-methylbenzamiido)benzamide, N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-3-(4-cyano-N-methylbenzamido)-4-fluorobenzamide, N-(5-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)-2-fluorophenyl)-2-chloro-N-methylnicotinamide, 3-benzamido-N-(4-(perfluoropropan-2-yl)-2,6-bis(trifluoromethyl)phenyl)benzamide,


2-chloro-N-(3-(4-(perfluoropropan-2-yl)-2,6-bis(trifluoromethyl)phenylcarbamoyl)phenyl)nicotinamide, N-methyl-N-(3-(4-(perfluoropropan-2-yl)-2,6-bis(trifluoromethyl)phenylcarbamoyl)phenyl)benzamide, 2-chloro-N-methyl-N-(3-(4-(perfluoropropan-2-yl)-2,6-bis(trifluoromethyl)phenylcarbamoyl)phenyl)nicotinamide, 3-benzamido-N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-N-methylbenzamide, N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-3-(3-cyanobenzamido)-N-methylbenzamide, N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-3-(4-cyanobenzamido)-N-methylbenzamide, N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-3-(3-cyano-N-methylbenzamido)-N-methylbenzamide, N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-3-(4-cyano-N-methylbenzamido)-N-methylbenzamide, 2-bromo-N-(3-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-N-methylnicotinamide, 3-benzamido-N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-2-fluorobenzamide, 2-bromo-N-(3-((2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)(methyl)carbamoyl)phenyl)nicotinamide, N-(3-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)-2-fluorophenyl)-2-chloronicotinamide, 3-benzamido-N-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)benzamide, 2-chloro-N-(3-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)nicotinamide, N-(3-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-4-cyano-2-fluoro-N-methylbenzamide, N-(3-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-4-cyano-2-fluorobenzamide, 3-cyano-N-(3-(4-(perfluoropropan-2-yl)-2,6-bis(trifluoromethyl)phenylcarbamoyl)phenyl)benzamide, 3-(4-cyanobenzamido)-N-(4-(perfluoropropan-2-yl)-2,6-bis(trifluoromethyl)phenyl)benzamide, 3-cyano-N-methyl-N-(3-(4-(perfluoropropan-2-yl)-2,6-bis(trifluoromethyl)phenylcarbamoyl)phenyl)benzamide, 4-cyano-N-methyl-N-(3-(4-(perfluoropropan-2-yl)-2,6-bis(trifluoromethyl)phenylcarbamoyl)phenyl)benzamide,


N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-3-(4-cyanobenzamido)-2-fluorobenzamide, N-(3-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)-2-fluorophenyl)-2-chloro-N-methylnicotinamide, N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-3-(4-cyano-N-methylbenzamido)-2-fluorobenzamide, N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-2-fluoro-3-(N-methylbenzamido)benzamide, N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-3-(3-cyano-N-methylbenzamido)-2-fluorobenzamide, N-(3-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-2-chloro-4-cyano-N-methylbenzamide, 3-benzamido-N-methyl-N-(4-(perfluoropropan-2-yl)-2,6-bis(trifluoromethyl)phenyl)benzamide, 2-chloro-N-(3-(methyl(4-(perfluoropropan-2-yl)-2,6-bis(trifluoromethyl)phenyl)carbamoyl)phenyl)nicotinamide, 3-(3-cyanobenzamido)-N-methyl-N-(4-(perfluoropropan-2-yl)-2,6-bis(trifluoromethyl)phenyl)benzamide, 2-bromo-N-(3-(methyl(4-(perfluoropropan-2-yl)-2,6-bis(trifluoromethyl)phenyl)carbamoyl)phenyl)nicotinamide, 2-bromo-N-(3-(4-(perfluoropropan-2-yl)-2,6-bis(trifluoromethyl)phenylcarbamoyl)phenyl)nicotinamide, 2-bromo-N-methyl-N-(3-(4-(perfluoropropan-2-yl)-2,6-bis(trifluoromethyl)phenylcarbamoyl)phenyl)nicotinamide, 3-(4-cyanobenzamido)-N-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)benzamide, 3-cyano-N-(3-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)benzamide, 2-bromo-N-(3-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)nicotinamide, 4-cyano-N-(3-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-N-methylbenzamide, 2-chloro-N-(3-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-N-methylnicotinamide, N-(3-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-2-iodonicotinamide, N-(3-(2-bromo--(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)-2-fluorophenyl)-N-methylnicotinamide, N-(3-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)-2-fluorophenyl)-6-fluoro-N-methylnicotinamide, N-(3-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)-2-fluorophenyl)-4-cyano-2-fluoro-N-methylbenzamide,


N-(3-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)-2-fluorophenyl)-6-chloro-N-methylnicotinamide, N-(3-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)-2-fluorophenyl)-3,5-dicyano-N-methylbenzamide, 3-benzamido-2-fluoro-N-(4-(perfluoropropan-2-yl)-2,6-bis(trifluoromethyl)phenyl)benzamide, N-(3-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-3,5-dicyano-N-methylbenzamide, 3-benzamido-2-fluoro-N-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)benzamide, 2-chloro-N-(2-fluoro-3-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)nicotinamide, 3-benzamido-N-(2-bromo-6-(perfluoroethyl)-4-(perfluoropropan-2-yl)phenyl)-2-fluorobenzamide, 3-benzamido-N-(2-bromo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenyl)-2-fluorobenzamide, N-(3-(2-bromo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)-2-fluorophenyl)-2-chloronicotinamide, N-(2-bromo-6-(perfluoroethyl)-4-(per-fluoropropan-2-yl)phenyl)-3-(4-cyanobenzamido)-2-fluorobenzamide, N-(2-bromo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenyl)-2-fluoro-3-(N-methylbenzamido)benzamide, N-(2-bromo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenyl)-3-(3-cyano-N-methylbenzamido)-2-fluorobenzamide, N-(2-bromo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenyl)-3-(4-cyano-N-methylbenzamido)-2-fluorobenzamide, 2-fluoro-N-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-3-(N-methylbenzamiido)benzamide, 3-(4-cyano-N-methylbenzamido)-2-fluoro-N-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)benzamide, N-(3-(2-bromo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-N-methylbenzamide, 3-benzamido-N-(2-bromo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenyl)benzamide, 3-benzamido-2-fluoro-N-(2-iodo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenyl)benzamide, 2-fluoro-N-(2-iodo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenyl)-3-(N-methylbenzamido)benzamide, 3-(4-cyano-N-methylbenzamido)-2-fluoro-N-(2-iodo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenyl)benzamide,


3-(3-cyano-N-methylbenzamido)-2-fluoro-N-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)benzamide, 2-fluoro-N-(2-fluoro-3-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-N-methylbenzamide, 2-fluoro-3-(3-fluoro-N-methylbenzamido)-N-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)benzamide, 2-fluoro-3-(4-fluoro-N-methylbenzamiido)-N-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)benzamide, 2,6-difluoro-N-(2-fluoro-3-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-N-methylbenzamide, 6-chloro-N-(2-fluoro-3-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)nicotinamide, 3-(3-cyanobenzamido)-2-fluoro-N-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)benzamide, 3-(4-cyanobenzamido)-2-fluoro-N-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)benzamide, 2-fluoro-3-(2-fluorobenzamido)-N-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)benzamide, 2-fluoro-3-(3-fluorobenzamido)-N-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)benzamide, N-(3-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)-2-fluorophenyl)-2-fluoro-N-methylbenzamide, N-(3-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)-2-fluorophenyl)-2,6-difluoro-N-methylbenzamide, N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-2-fluoro-3-(3-fluoro-N-methylbenzamido)benzamide, N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-2-fluoro-3-(4-fluoro-N-methylbenzamido)benzamide, N-(3-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)-2-fluorophenyl)-2-chloronicotinamide, N-(3-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)-2-fluorophenyl)-6-chloronicotinamide, N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-3-(3-cyanobenzamido)-2-fluorobenzamide, N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-2-fluoro-3-(2-fluorobenzamido)benzamide, N-(2-bromo--(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-2-fluoro-3-(3-fluorobenzamido)benzamide, N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-2-fluoro-3-(4-fluorobenzamido)benzamide, N-(3-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)-2-fluorophenyl)-N-methylnicotinamide, 2-chloro-N-(2-fluoro-3-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-N-methylnicotinamide,


2-fluoro-3-(4-fluorobenzamido)-N-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)benzamide, 3-(2,6-difluorobenzamido)-2-fluoro-N-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)benzamide, 6-chloro-N-(2-fluoro-3-(2-iodo-4-(perfluoropropan-2-yl)-6-(rifluoromethyl)phenylcarbamoyl)phenyl)-N-methylnicotinamide, N-(3-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-6-chloronicotinamide, N-(3-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-2-fluorobenzamide, N-(2-bromo-4-(perfluowopropan-2-yl)-6-(trifluoromethyl)phenyl)-3-(3-fluorobenzamido)benzamide, N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-3-(4-fluorobenzamido)benzamide, N-(3-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-2,6-difluorobenzamide, N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-3-(2,6-difluorobenzamido)-2-fluorobenzamide, 3-fluoro-N-(3-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)benzamide, 3-(4-fluorobenzamido)-N-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)benzamide, 2-fluoro-N-(3-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)benzamide, 2,6-difluoro-N-(3-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)benzamide, 6-chloro-N-(3-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)nicotinamide, 6-chloro-N-(3-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-N-methylnicotinamide, 3-cyano-N-(3-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-N-methylbenzamide, 2-fluoro-N-(3-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-N-methylbenzamide, 3-fluoro-N-(3-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-N-methylbenzamide, 4-fluoro-N-(3-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-N-methylbenzamide, N-(3-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-2-fluoro-N-methylbenzamide,


N-(3-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-3-fluoro-N-methylbenzamide, N-(3-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-4-fluoro-N-methylbenzamide, N-(3-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-2,6-difluoro-N-methylbenzamide, 2,4-dichloro-N-(3-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)benzamide, 3-(2,4-dichlorobenzamido)-2-fluoro-N-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)benzamide, 2,6-difluoro-N-(3-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-N-methylbenzamide, 3-(2-chloro-4-fluorobenzamido)-2-fluoro-N-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)benzamide, N-(3-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-N-methylbenzamide, 3-benzamido-N-(2-iodo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenyl)benzamide, 2-cloro-N-(3-(2-iodo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)nicotinamide, 6-chloro-N-(3-(2-iodo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)nicotinamide, 3-cyano-N-(3-(2-iodo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)benzamide, 3-(4-cyanobenzamido)-N-(2-iodo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenyl)benzamide, 2-fluoro-N-(3-(2-iodo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)benzamide, 3-fluoro-N-(3-(2-iodo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)benzamide, 3-(4-fluorobenzamido)-N-(2-iodo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenyl)benzamide, 2,6-difluoro-N-(3-(2-iodo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)benzamide, N-(3-(2-iodo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-N-methylbenzamide, 2-chloro-N-(3-(2-iodo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-N-methylnicotinamide, 3-cyano-N-(3-(2-iodo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-N-methylbenzamide, 4-cyano-N-(3-(2-iodo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-N-methylbenzamide,


3-fluoro-N-(3-(2-iodo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-N-methylbenzamide, 4-fluoro-N-(3-(2-iodo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-N-methylbenzamide, N-(3-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)-2-fluorophenyl)-N-methylisonicotinamide, 3-((3-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)-2-fluorophenyl)(methyl)carbamoyl)pyridine 1-oxide, 4-((3-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)-2-fluorophenyl)(methyl)carbamoyl)pyridine 1-oxide, 2-chloro-4-fluoro-N-(3-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)benzamide, N-(3-(2-bromo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-2-chloronicotinamide, N-(2-bromo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenyl)-3-(3-cyanobenzamido)benzamide, N-(3-(2-bromo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-2-fluorobenzamide, N-(2-bromo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenyl)-3-(3-fluorobenzamido)benzamide, N-(3-(2-bromo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-6-chloronicotinamide, N-(2-bromo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenyl)-3-(4-cyanobenzamido)benzamide, N-(2-bromo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenyl)-3-(4-fluorobenzamido)benzamide, N-(3-(2-bromo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-2,6-difluorobenzamide, N-(3-(2-bromo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-2-chloro-N-methylnicotinamide, N-(3-(2-bromo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-3-cyano-N-methylbenzamide, N-(3-(2-bromo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-2-fluoro-N-methylbenzamide, N-(3-(2-bromo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-3-fluoro-N-methylbenzamide, N-(3-(2-bromo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-6-chloro-N-methylnicotinamide, N-(3-(2-bromo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-4-cyano-N-methylbenzamide,


N-(3-(2-bromo--(perfluorobutan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-4-fluoro-N-methylbenzamide, N-(3-(2-bromo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-2,6-difluoro-N-methylbenzamide, 6-chloro-N-(2-fluoro-3-(2-iodo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)nicotinamide, 3-(3-cyanobenzamido)-2-fluoro-N-(2-iodo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenyl)benzamide, 3-(4 cyanobenzamido)-2-fluoro-N-(2-iodo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenyl)benzamide, 2-fluoro-3-(2-fluorobenzamido)-N-(2-iodo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenyl)benzamide, 2-fluoro-3-(3-fluorobenzamido)-N-(2-iodo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenyl)benzamide, 2-fluoro-3-(4-fluorobenzamido)-N-(2-iodo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenyl)benzamide, 3-(2,6-difluorobenzamido)-2-fluoro-N-(2-iodo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenyl)benzamide, N-(3-(2-bromo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)-2-fluorophenyl)-6-chloronicotinamide, N-(2-bromo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenyl)-3-(3-cyanobenzamido)-2-fluorobenzamide, N-(2-bromo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenyl)-3-(4-cyanobenzamido)-2-fluorobenzamide, N-(2-bromo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenyl)-2-fluoro-3-(2-fluorobenzamido)benzamide, N-(2-bromo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenyl)-2-fluoro-3-(3-fluorobenzamido)benzamide, N-(2-bromo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenyl)-2-fluoro-3-(4-fluorobenzamido)benzamide, N-(2-bromo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenyl)-3-(2,6-difluorobenzamido)-2-fluorobenzamide, 2-chloro-N-(2-fluoro-3-(2-iodo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-N-methylnicotinamide, 6-chloro-N-(2-fluoro-3-(2-iodo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-N-methylnicotinamide, 3-(3-cyano-N-methylbenzamido)-2-fluoro-N-(2-iodo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenyl)benzamide, 2-fluoro-N-(2-fluoro-3-(2-iodo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-N-methylbenzamide,


2-fluoro-3-(3-fluoro-N-methylbenzamido)-N-(2-iodo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenyl)benzamide, 2-fluoro-3-(4-fluoro-N-methylbenzamido)-N-(2-iodo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenyl)benzamide, 2-chloro-4,5-difluoro-N-(3-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)benzamide, 2-chloro-4-fluoro-N-(3-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-N-methylbenzamide, N-(3-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-2-chloro-4-fluorobenzamide, 2-chloro-N-(3-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)benzamide, 3-(2-chlorobenzamido)-2-fluoro-N-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)benzamide, 2-chloro-N-(3-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-N-methylbenzamide, N-(3-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-2-chlorobenzamide, 2-chloro-N-(3-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-4-nitrobenzamide, N-(2-fluoro-3-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-N-methylnicotinamide, 3-((2-fluoro-3-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)(methyl)carbamoyl)pyridine 1-oxide, 4-bromo-2-chloro-N-(3-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)benzamide, 2-bromo-4-chloro-N-(3-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoro methyl)phenylcarbamoyl)phenyl)benzamide, 2-bromo-4-fluoro-N-(3-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)benzamide, 2-fluoro-3-(3-fluoro-N-methylbenzamido)-N-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-N-methylbenzamide, N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-2-fluoro-N-methy 1-3-(N-methylbenzamido)benzamide, or N-(2-chloro-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-2-fluoro-3-(N-methylbenzamido)benzamide.


<12> The amide derivative according to <2>, wherein in Formula (7), at least one of X represents a chlorine atom, a bromine atom, an iodine atom, a C1-C6 alkyl group, a C1-C6 haloalkyl group, a C3-C9 cycloalkyl group, a C3-C9 halocycloalkyl group, a C2-C6 alkenyl group, a C2-C6 haloalkenyl group, a C2-C6 alkynyl group, a C2-C6 haloalkynyl group, a C1-C6 alkoxy group, a C1-C6 haloalkoxy group, a C2-C6 alkenyloxy group, a C2-C6 haloalkenyloxy group, a C2-C6 alkynyloxy group, a C2-C6 haloalkynyloxy group, a C3-C9 cycloalkoxy group, a C3-C9 halocycloalkoxy group, a C1-C6 alkylthio group, a C1-C6 haloalkylthio group, a C1-C6 alkylsulfinyl group, a C1-C6 haloalkylsulfinyl group, a C1-C6 alkylsulfonyl group, a C1-C6 haloalkylsulfonyl group, a C1-C6 alkylsulfonyloxy group, a C1-C6 haloalkylsulfonyloxy group, a C2-C7 alkylcarbonyl group, a C2-C7 haloalkylcarbonyl group, a C3-C7 alkenylcarbonyl group, a C3-C7 haloalkenylcarbonyl group, a C3-C7 alkynylcarbonyl group, a C3-C7 haloalkynylcarbonyl group, a C4-C10 cycloalkylcarbonyl group, a C4-C10 halocycloalkylcarbonyl group, a C2-C7 alkylcarbonyloxy group, a C2-C7 haloalkylcarbonyloxy group, arylcarbonyloxy group, a C2-C7 alkoxycarbonyl group, a C2-C7 haloalkoxycarbonyl group, a C3-C7 alkenyloxycarbonyl group, a C3-C7 haloalkenyloxycarbonyl group, a C3-C7 alkynyloxycarbonyl group, a C3-C7 haloalkynyloxycarbonyl group, a C4-C10 cycloalkyloxycarbonyl group, a C4-C10 halocycloalkyloxycarbonyl group, a C2-C7 alkylcarbonylamino group, a C2-C7 haloalkylcarbonylamino group, a C2-C7 alkoxycarbonylamino group, a C2-C7 haloalkoxycarbonylamino group, a C2-C7 alkoxycarbonyloxy group, a C2-C7 haloalkoxycarbonyloxy group, an arylcarbonylamino group, an amino group, a carbamoyl group, a cyano group, a hydroxy group, pentafluorosulfanyl group, a C1-C6 alkylamino group, a C1-C6 haloalkylamino group, a C2-C6 alkenylamino group, a C2-C6 haloalkenylamino group, a C2-C6 alkynylamino group, a C2-C6 haloalkynylamino group, a C3-C9 cycloalkylamino group, a C3-C9 halocycloalkylamino group, a C2-C7 alkylaminocarbonyl group, a C2-C7 haloalkylaminocarbonyl group, a C3-C7 alkenylaminocarbonyl group, a C3-C7 haloalkenylaminocarbonyl group, a C3-C7 alkynylaminocarbonyl group, a C3-C7 haloalkynylaminocarbonyl group, a C4-C10 cycloalkylaminocarbonyl group, a C4-C10 halocycloalkylaminocarbonyl group, a phenyl group, or a heterocyclic group, and when there are plural X's, each X may be the same as or different from an other. Y1 represents a halogen atom, a C1-C6 haloalkoxy group, or a C1-C3 haloalkyl group. Y5 represents a C1-C6 haloalkoxy group, or C1-C3 haloalkyl group.


<13> The amide derivative according to <12>, wherein in Formula (7), Y3 represents a C2-C4 perfluoroalkyl group.


<14> The amide derivative according to <13>, wherein in Formula (7), Y1 represents a halogen atom or a C1-C3 haloalkyl group, and Y5 represents a C1-C3 haloalkyl group.


<15> The amide derivative according to <14>, wherein in Formula (7), Y2 and Y4 represent a hydrogen atom.


<16> The amide derivative according to <15>, wherein in Formula (7), X1 to X4 each independently represents a hydrogen atom, a halogen atom, or a cyano group.


<17> The amide derivative according to <1>, which is represented by the following Formula (9):




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Wherein, in Formula (9), n represents 4, and X, Y1 to Y5, Q2, G1 to G3, R1, and R2 have the same definitions as X, Y1 to Y5, Q2, G1 to G3, R1, and R2, respectively, in Formula (1).


<18> The amide derivative according to <17>, wherein in Formula (9), Y1 represents a halogen atom, a C1-C6 haloalkoxy group, or a C1-C3 haloalkyl group, and Y5 is a C1-C6 haloalkoxy group or a C1-C3 haloalkyl group.


<19> The amide derivative according to <18>, wherein in Formula (9), Y3 represents a C2-C4 perfluoroalkyl group.


<20> The amide derivative according to <19>, wherein in Formula (9), Y1 and Y5 represent halogen atoms or C1-C3 haloalkyl groups, and either Y1 or Y5 represent a C1-C3 haloalkyl group.


<21> The amide derivative according to <20>, wherein in Formula (9), Y2 and Y4 represent hydrogen atoms.


<22> The amide derivative according to <21>, wherein in Formula (9), X1 to X4 each independently represents a hydrogen atom, a halogen atom, or a cyano group.


<23> The amide derivative according to <1>, wherein in Formula (1), K represents a non-metal atom group necessary for forming a cyclic linking group derived from pyridine, pyridine-N-oxide, pyrimidine, pyrazine, pyridazine, triazine, pyrrole, pyrazole, imidazole, oxazole, isoxazole, thiazole, isothiazole, furan, thiophene, oxadiazole, thiodiazole, or triazole, in combination with A and two carbon atoms to which A bonds.


<24> The amide derivative according to <23>, wherein in Formula (1), K represents a non-metal atom group necessary for forming a cyclic linking group derived from pyridine, in combination with A and two carbon atoms to which A bonds, and when T is —C(=G1)-Q1, Y1 and Y5 each independently represents a halogen atom or a C1-C3 haloalkyl group.


<25> The amide derivative according to <23>, wherein in Formula (1), K represents a non-metal atom group necessary for forming a cyclic linking group derived from pyrrole, pyrazole, imidazole, oxazole, isoxazole, thiazole, isothiazole, furan, thiophene, oxadiazole, thiodiazole, or trizole, in combination with A and two carbon atoms to which A bonds, and in a case where T represents —C(=G1)-Q1, R1 represents an oxygen atom, a halogen atom, a hydroxy group, a nitro group, a nitroso group, a trimethylsilyl group, a t-butyldimethylsilyl group, a cyano group, an amino group, a C1-C6 alkyl group which may have a substituent, a C1-C6 haloalkyl group which may have a substituent, a C2-C7 alkylcarbonyl group, a C2-C7 haloalkylcarbonyl group, a C2-C6 alkenyl group which may have a substituent, a C2-C6 haloalkenyl group which may have a substituent, a C2-C6 alkynyl group which may have a substituent, a C2-C6 haloalkynyl group which may have a substituent, a C2-C7 alkoxycarbonyl group, a C2-C7 haloalkoxycarbonyl group, a C3-C7 alkenyloxycarbonyl group, a C3-C7 haloalkenyloxycarbonyl group, a C3-C7 alkynyloxycarbonyl group, a C3-C7 haloalkynyloxycarbonyl group, a phenoxycarbonyl group, a C2-C7 alkylaminocarbonyl group, a C2-C7 haloalkylaminocarbonyl group, a C2-C7 alkylcarbonyloxy group, a C2-C7 haloalkylcarbonyloxy group, a benzoyl group, a C1-C6 alkoxy group, a C1-C6 haloalkoxy group, a C1-C6 alkylthio group, a C1-C6 haloalkylthio group, a C1-C6 alkylsulfinyl group, a C1-C6 haloalkylsulfinyl group, a C1-C6 alkylsulfonyl group, a C1-C6 haloalkylsulfonyl group, a benzenesulfonyl group, a benzylsulfonyl group, a benzyl group, or —C(═O)C(═O)R7 (wherein R7 represents a C1-C6 alkyl group, a C1-C6 haloalkyl group, a C1-C6 alkoxy group, or a C1-C6 haloalkoxy group).


<26> The amide derivative according to <23>, wherein in Formula (1), K represents a non-metal atom group necessary for forming a cyclic linking group derived from pyrrole, pyrazole, imidazole, oxazole, isoxazole, thiazole, isothiazole, furan, thiophene, oxadiazole, thiodiazole, or trizole, in combination with A and two carbon atoms to which A bonds, and in a case where T represents —C(=G1)-Q1, R2 represents an oxygen atom, a halogen atom, a hydroxy group, a nitro group, a nitroso group, a trimethylsilyl group, a t-butyldimethylsilyl group, a cyano group, an amino group, a C1-C6 alkyl group which may have a substituent, a C1-C6 haloalkyl group which may have a substituent, a C2-C7 alkylcarbonyl group, a C2-C7 haloalkylcarbonyl group, a C2-C6 alkenyl group which may have a substituent, a C2-C6 haloalkenyl group which may have a substituent, a C2-C6 alkynyl group which may have a substituent, a C2-C6 haloalkynyl group which may have a substituent, a C2-C7 alkoxycarbonyl group, a C2-C7 haloalkoxycarbonyl group, a C3-C7 alkenyloxycarbonyl group, a C3-C7 haloalkenyloxycarbonyl group, a C3-C7 alkynyloxycarbonyl group, a C3-C7 haloalkynyloxycarbonyl group, a phenoxycarbonyl group, a C2-C7 alkylaminocarbonyl group, a C2-C7 haloalkylaminocarbonyl group, a C2-C7 alkylcarbonyloxy group, a C2-C7 haloalkylcarbonyloxy group, a benzoyl group, a C1-C6 alkoxy group, a C1-C6 haloalkoxy group, a C1-C6 alkylthio group, a C1-C6 haloalkylthio group, a C1-C6 alkylsulfinyl group, a C1-C6 haloalkylsulfinyl group, a C1-C6 alkylsulfonyl group, a C1-C6 haloalkylsulfonyl group, a benzenesulfonyl group, a benzylsulfonyl group, a benzyl group, or —C(═O)C(═O)R7 (wherein R7 represents a C1-C6 alkyl group, a C1-C6 haloalkyl group, a C1-C6 alkoxy group, or a C1-C6 haloalkoxy group).


<27> The amide derivative according to any one of <23> to <26>, wherein in Formula (1), Y3 represents a C2-C4 perfluoroalkyl group.


<28> The amide derivative according to <27>, wherein in Formula (1), Y1 and Y5 each independently represent a halogen atom or a C1-C3 haloalkyl group, and either Y1 or Y5 represent a C1-C3 haloalkyl group.


<29> The amide derivative according to <28>, wherein in Formula (1), Y2 and Y4 represent hydrogen atoms.


<30> The amide derivative according to <29>, wherein in Formula (1), K represents a non-metal atom group necessary for forming a cyclic linking group derived from pyridine, pyridine-N-oxide, pyrrole, thiazole, furan, or thiophene, in combination with A and two carbon atoms to which A bonds.


<31> The amide derivative according to <29>, wherein in Formula (1), K represents a non-metal atom group necessary for forming a cyclic linking group derived from pyridine, pyridine-N-oxide, or thiazole, in combination with A and two carbon atoms to which A bonds.


<32> The amide derivative according to <16>, wherein in Formula (7), G1 and G3 represent oxygen atoms.


<33> The amide derivative according to <22>, wherein in Formula (9), G1, G2, and G3 represent oxygen atoms.


<34> The amide derivative according to <31>, wherein in Formula (1), G1, G2, and G3 represent oxygen atoms.


<35> A pest control agent comprising at least one amide derivative according to any one of <1> to <34> as an active ingredient.


<36> An agricultural chemical comprising at least one amide derivative according to any one of <1> to <34> as an active ingredient.


<37> A pesticide comprising at least one amide derivative according to any one of <1> to <34> as an active ingredient.


<38> A pest controlling method, comprising applying a chemical agent according to any one of <35> to <37>.


<39> A compound represented by the following Formula (56):




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Wherein, wherein Y5 represents a C1-C3 haloalkyl group, and Y2, Y3, and Y4 represent the same definitions as Y2, Y3, and Y4, respectively, in <1>.


<40> A compound represented by the following Formula (57):




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Wherein Y5 represents a C1-C3 haloalkyl group, and Y1, Y2, Y3, and Y4 represent the same definitions as Y1, Y2, Y3, and Y4, respectively, in <1>.


<41> The compound according to <40>, wherein in Formula (57), Y1 represents a halogen atom.


<42> A method for producing a compound represented by the following Formula (57a) according to <41>, including reacting a compound represented by Formula (56) according to <39> with a halogenating agent:




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Wherein Y5 represents a C1-C3 haloalkyl group, Y2, Y3, and Y4 represent the same definitions as Y2, Y3, and Y4, respectively, in <1>, and Y1 represents a halogen atom.


<43> A compound represented by the following Formula (60a):




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Wherein A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5 have the same definitions as A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5, respectively, in <1>. In a case where K forms a benzene ring together with A and two carbon atoms to which A bonds and all X's represent hydrogen atoms, Y5 represents a C1-C3 haloalkyl group. Further, when K forms a benzene ring together with A and two carbon atoms to which A bonds and X's are cyano groups, Y5 represents a C1-C6 haloalkoxy group or a C1-C3 haloalkyl group.


<44> A method for producing a compound represented by the following Formula (60a) according to <43>, comprising reacting a compound represented by the following Formula (59) with a compound represented by the following Formula (57b):




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Wherein LG represents a functional group having a leaving ability, such as a halogen atom, a hydroxy group, or the like, and A, K, X, n, and G3 have the same definitions as A, K, X, n, and G3, respectively, in <1>.




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Wherein Y1, Y2, Y3, Y4, and Y5 have the same definitions as Y1, Y2, Y3, Y4, and Y5, respectively, in <1>.




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Wherein A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5 have the same definitions as A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5, respectively, in <1>. In a case where K forms a benzene ring together with A and two carbon atoms to which A bonds and X's represent all hydrogen atoms, Y5 represents a C1-C3 haloalkyl group. Further, in a case where K forms a benzene ring together with A and two carbon atoms to which A bonds and X represents a cyano group, Y5 represents a C1-C6 haloalkoxy group or a C1-C3 haloalkyl group.


<45> A compound represented by the following Formula (61a):




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Wherein A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5 represent the same definitions as A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5, respectively, in <1>. In a case where K forms a benzene ring together with A and two carbon atoms to which A bonds and all X's represent hydrogen atoms, Y5 represents a C1-C3 haloalkyl group. Further, when K forms a benzene ring together with A and two carbon atoms to which A bonds and X represents a cyano group, Y5 represents a C1-C6 haloalkoxy group or a C1-C3 haloalkyl group.


<46> A method for producing a compound represented by the following Formula (61a) according to <45>, including reacting a compound represented by Formula (60a) according to <43> with a reducing agent:




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Wherein A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5 have the same definitions as A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5, respectively, in <1>. In a case where K forms a benzene ring together with A and two carbon atoms to which A bonds and all X's represent hydrogen atoms, Y5 represents a C1-C3 haloalkyl group. Further, when K forms a benzene ring together with A and two carbon atoms to which A bonds and X represents a cyano group, Y5 represents a C1-C6 haloalkoxy group or a C1-C3 haloalkyl group.


<47> A compound represented by the following Formula (69):




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Wherein T, A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y have the same definitions as T, A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5, respectively, in <1>.


<48> A method for producing a compound represented by the following Formula (69) according to <47>, including reacting a compound represented by the following Formula (61b) with a compound represented by the following Formula (62):




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Wherein A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5 have the same definitions as A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5, respectively, in <1>.





T-LG  Formula (62)


Wherein LG represents a functional group having a leaving ability, such as a halogen atom, a hydroxy group, and the like, and T represents the same definition as T in <1>.




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Wherein T, A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5 represent the same definitions as T, A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5 respectively, in <1>.


<49> A compound represented by the following Formula (51a):




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Wherein T, R1, A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5 have the same definitions as T, R1, A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5, respectively, in <1>.


<50> A method for producing a compound represented by the following Formula (51b), including reacting a compound represented by the following Formula (69) according to <47> with a compound represented by the following Formula (64):




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Wherein T, A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5 have the same definitions as T, A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5, respectively, in <1>.





R1-LG  Formula (64)


Wherein LG represents a functional group having a leaving ability, such as a halogen atom, a hydroxy group, or the like, R1 represents a trimethylsilyl group, a t-butyldimethylsilyl group, a cyano group, a C1-C6 alkyl group which may have a substituent, a C1-C6 haloalkyl group which may have a substituent, a C2-C7 alkylcarbonyl group, a C2-C7 haloalkylcarbonyl group, a C2-C6 alkenyl group which may have a substituent, a C2-C6 haloalkenyl group which may have a substituent, a C2-C6 alkynyl group which may have a substituent, a C2-C6 haloalkynyl group which may have a substituent, a C2-C7 alkoxycarbonyl group, a C2-C7 haloalkoxycarbonyl group, a C3-C7 alkenyloxycarbonyl group, a C3-C7 haloalkenyloxycarbonyl group, a C3-C7 alkynyloxycarbonyl group, a C3-C7 haloalkynyloxycarbonyl group, a phenoxycarbonyl group, a C2-C7 alkylaminocarbonyl group, a C2-C7 haloalkylaminocarbonyl group, a C2-C7 alkylcarbonyloxy group, a C2-C7 haloalkylcarbonyloxy group, a benzoyl group, a C1-C6 alkylsulfinyl group, a C1-C6 haloalkylsulfinyl group, a C1-C6 alkylsulfonyl group, a C1-C6 haloalkylsulfonyl group, a benzenesulfonyl group, a benzylsulfonyl group, a benzyl group, or —C(═O)C(═O)R7 (wherein R7 represents a C1-C6 alkyl group, a C1-C6 haloalkyl group, a C1-C6 alkoxy group, or a C1-C6 haloalkoxy group.




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Wherein R1 represents the same definition as R1 in Formula (64), and T, A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5 have the same definitions as T, A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5, respectively, in <1>.


<51> A compound represented by the following Formula (57c):




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Wherein Y5 represents a C1-C6 haloalkoxy group or a C1-C3 haloalkyl group, R2 represents an oxygen atom, a halogen atom, a hydroxy group, a nitro group, a nitroso group, a trimethylsilyl group, a t-butyldimethylsilyl group, a cyano group, an amino group, a C1-C6 alkyl group which may have a substituent, a C1-C6 haloalkyl group which may have a substituent, a C2-C7 alkylcarbonyl group, a C2-C7 haloalkylcarbonyl group, a C2-C6 alkenyl group which may have a substituent, a C2-C6 haloalkenyl group which may have a substituent, a C2-C6 alkynyl group which may have a substituent, a C2-C6 haloalkynyl group which may have a substituent, a C2-C7 alkoxycarbonyl group, a C2-C7 haloalkoxycarbonyl group, a C3-C7 alkenyloxycarbonyl group, a C3-C7 haloalkenyloxycarbonyl group, a C3-C7 alkynyloxycarbonyl group, a C3-C7 haloalkynyloxycarbonyl group, a phenoxycarbonyl group, a C2-C7 alkylaminocarbonyl group, a C2-C7 haloalkylaminocarbonyl group, a C2-C7 alkylcarbonyloxy group, a C2-C7 haloalkylcarbonyloxy group, a benzoyl group, a C1-C6 alkoxy group, a C1-C6 haloalkoxy group, a C1-C6 alkylthio group, a C1-C6 haloalkylthio group, a C1-C6 alkylsulfinyl group, a C1-C6 haloalkylsulfinyl group, a C1-C6 alkylsulfonyl group, a C1-C6 haloalkylsulfonyl group, a benzenesulfonyl group, a benzylsulfonyl group, a benzyl group, or —C(═O)C(═O)R7 (wherein R7 represents a C1-C6 alkyl group, a C1-C6 haloalkyl group, a C1-C6 alkoxy group, or a C1-C6 haloalkoxy group), and Y1, Y2, Y3, and Y4 have the same definitions as Y1, Y2, Y3, and Y4, respectively, in <1>.


<52> A method for producing a compound represented by the following Formula (57m), including reacting a compound represented by the following Formula (57k) with a compound represented by the following Formula (66):




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Wherein Y5 represents a C1-C6 haloalkoxy group or a C1-C3 haloalkyl group, and Y1, Y2, Y3, and Y4 have the same definitions as Y1, Y2, Y3, and Y4, respectively, in <1>.





R2-LG  Formula (66)


Wherein, LG represents a functional group having a leaving ability, such as a halogen atom, a hydroxy group, or the like, R2 represents a trimethylsilyl group, a t-butyldimethylsilyl group, a cyano group, a C1-C6 alkyl group which may have a substituent, a C1-C6 haloalkyl group which may have a substituent, a C2-C7 alkylcarbonyl group, a C2-C7 haloalkylcarbonyl group, a C2-C6 alkenyl group which may have a substituent, a C2-C6 haloalkenyl group which may have a substituent, a C2-C6 alkynyl group which may have a substituent, a C2-C6 haloalkynyl group which may have a substituent, a C2-C7 alkoxycarbonyl group, a C2-C7 haloalkoxycarbonyl group, a C3-C7 alkenyloxycarbonyl group, a C3-C7 haloalkenyloxycarbonyl group, a C3-C7 alkynyloxycarbonyl group, a C3-C7 haloalkynyloxycarbonyl group, a phenoxycarbonyl group, a C2-C7 alkylaminocarbonyl group, a C2-C7 haloalkylaminocarbonyl group, a C2-C7 alkylcarbonyloxy group, a C2-C7 haloalkylcarbonyloxy group, a benzoyl group, a C1-C6 alkylsulfinyl group, a C1-C6 haloalkylsulfinyl group, a C1-C6 alkylsulfonyl group, a C1-C6 haloalkylsulfonyl group, a benzenesulfonyl group, a benzylsulfonyl group, a benzyl group, or —C(═O)C(═O)R7, wherein R7 represents a C1-C6 alkyl group, a C1-C6 haloalkyl group, a C1-C6 alkoxy group, or a C1-C6 haloalkoxy group.




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Wherein Y5 represents a C1-C6 haloalkoxy group or a C1-C3 haloalkyl group, R2 represents the same definition as R2 in Formula (66), and Y1, Y2, Y3, and Y4 have the same definitions as Y1, Y2, Y3, and Y4, respectively, in <1>.


<53> A method for producing a compound represented by the following Formula (57n), including reacting a compound represented by the following Formula (57k) according to <52> with an aldehyde:




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Wherein Y5 represents a C1-C6 haloalkoxy group or a C1-C3 haloalkyl group, and Y1, Y2, Y3, and Y4 have the same definitions as Y1, Y2, Y3, and Y4, respectively, in <1>.




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Wherein Y5 represents a C1-C6 haloalkoxy group or a C1-C3 haloalkyl group, R2 represents a C1-C6 alkyl group which may have a substituent, a C1-C6 haloalkyl group which may have a substituent, or a benzyl group, and Y1, Y2, Y3, and Y4 have the same definitions as Y1, Y2, Y3, and Y4, respectively, in <1>.


<54> A compound represented by the following Formula (60):




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Wherein R2 represents the same definition as R2 in <51>, and A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5 have the same definitions as A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5, respectively, in <1>.


<55> A method for producing a compound represented by the following Formula (60e), including reacting a compound represented by the following Formula (60f) with a compound represented by the following Formula (66) according to <52>:




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Wherein A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5 have the same definitions as A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5, respectively, in <1>.





R2-LG  Formula (66)


Wherein LG represents a functional group having a leaving ability, such as a halogen atom, a hydroxy group, or the like, R2 represents a trimethylsilyl group, a t-butyldimethylsilyl group, a cyano group, a C1-C6 alkyl group which may have a substituent, a C1-C6 haloalkyl group which may have a substituent, a C2-C7 alkylcarbonyl group, a C2-C7 haloalkylcarbonyl group, a C2-C6 alkenyl group which may have a substituent, a C2-C6 haloalkenyl group which may have a substituent, a C2-C6 alkynyl group which may have a substituent, a C2-C6 haloalkynyl group which may have a substituent, a C2-C7 alkoxycarbonyl group, a C2-C7 haloalkoxycarbonyl group, a C3-C7 alkenyloxycarbonyl group, a C3-C7 haloalkenyloxycarbonyl group, a C3-C7 alkynyloxycarbonyl group, a C3-C7 haloalkynyloxycarbonyl group, a phenoxycarbonyl group, a C2-C7 alkylaminocarbonyl group, a C2-C7 haloalkylaminocarbonyl group, a C2-C7 alkylcarbonyloxy group, a C2-C7 haloalkylcarbonyloxy group, a benzoyl group, a C1-C6 alkylsulfinyl group, a C1-C6 haloalkylsulfinyl group, a C1-C6 alkylsulfonyl group, a C1-C6 haloalkylsulfonyl group, a benzenesulfonyl group, a benzylsulfonyl group, a benzyl group, or —C(═O)C(═O)R7 (wherein R7 represents a C1-C6 alkyl group, a C1-C6 haloalkyl group, a C1-C6 alkoxy group, or a C1-C6 haloalkoxy group.




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Wherein R2 has the same definition as R2 in Formula (66), and A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5 have the same definitions as A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5, respectively, in <1>.


<56> A method for producing a compound represented by the following Formula (60) according to <54>, including reacting a compound represented by the following Formula (57d) with a compound represented by the following Formula (59) according to <44>:




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Wherein R2 has the same definition as R2 in <51>, and Y1, Y2, Y3, Y4, and Y5 have the same definitions as Y1, Y2, Y3, Y4, and Y5 respectively, in <1>.




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Wherein LG represents a functional group having a leaving ability, such as a halogen atom, a hydroxy group, or the like, and A, K, X, n, and G3 have the same definitions as A, K, X, n, and G3, respectively, in <1>.




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Wherein R2 has the same definition as R2 in <51>, and A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5 have the same definitions as A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5, respectively, in <1>.


<57> A compound represented by the following Formula (61):




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Wherein R2 has the same definition as R2 in <51>, and A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5 have the same definitions as A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5, respectively, in <1>.


<58> A method for producing a compound represented by the following Formula (61) according to <57>, including the compound represented by Formula (60) according to <54> in the presence of a reducing agent:




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Wherein R2 has the same definition as R2 in <51>, and A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5 have the same definitions as A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5, respectively, in <1>.


<59> A compound represented by the following Formula (63):




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Wherein T, R2, A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5 have the same definitions as T, R2, A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5, respectively, in <1>.


<60> A method for producing a compound represented by the following Formula (63) according to <59>, including reacting a compound represented by the following Formula (61e) with a compound represented by the following Formula (62) according to <48>:




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Wherein R2, A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5 have the same definitions as R2, A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5, respectively, in <1>.





T-LG  Formula (62)


(wherein LG represents a functional group having a leaving ability, such as a halogen atom, a hydroxy group, or the like, and T has the same definition as T in <1>.




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Wherein T, R2, A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5 represent the same definitions as T, R2, A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5, respectively, in <1>.


<61> A method for producing a compound represented by the following Formula (1b), including reacting a compound represented by the following Formula (63) according to <59> with a compound represented by the following Formula (64) according to <50>:




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Wherein T, R2, A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5 have the same definitions as T, R2, A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5, respectively, in <1>.





R1-LG  Formula ((64)


Wherein, LG represents a functional group having a leaving ability, such as a halogen atom, a hydroxy group, or the like, R1 represents a trimethylsilyl group, a t-butyldimethylsilyl group, a cyano group, a C1-C6 alkyl group which may have a substituent, a C1-C6 haloalkyl group which may have a substituent, a C2-C7 alkylcarbonyl group, a C2-C7 haloalkylcarbonyl group, a C2-C6 alkenyl group which may have a substituent, a C2-C6 haloalkenyl group which may have a substituent, a C2-C6 alkynyl group which may have a substituent, a C2-C6 haloalkynyl group which may have a substituent, a C2-C7 alkoxycarbonyl group, a C2-C7 haloalkoxycarbonyl group, a C3-C7 alkenyloxycarbonyl group, a C3-C7 haloalkenyloxycarbonyl group, a C3-C7 alkynyloxycarbonyl group, a C3-C7 haloalkynyloxycarbonyl group, a phenoxycarbonyl group, a C2-C7 alkylaminocarbonyl group, a C2-C7 haloalkylaminocarbonyl group, a C2-C7 alkylcarbonyloxy group, a C2-C7 haloalkylcarbonyloxy group, a benzoyl group, a C1-C6 alkylsulfinyl group, a C1-C6 haloalkylsulfinyl group, a C1-C6 alkylsulfonyl group, a C1-C6 haloalkylsulfonyl group, a benzenesulfonyl group, a benzylsulfonyl group, a benzyl group, or —C(═O)C(═O)R7, wherein R7 represents a C1-C6 alkyl group, a C1-C6 haloalkyl group, a C1-C6 alkoxy group, or a C1-C6 haloalkoxy group.




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Wherein R1 has the same definition as R1 in Formula (64), and R2, A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5 have the same definitions as R2, A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5, respectively, in <1>.


<62> A compound represented by the following Formula (65a):




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Wherein R1, R2, A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5 have the same definitions as R1, R2, A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5, respectively, in <1>. In a case where K forms a benzene ring together with A and two carbon atoms to which A bonds, all X's represent hydrogen atoms, and R2 represents a hydrogen atom, Y5 is a C1-C3 haloalkyl group. Further, in a case where K forms a benzene ring together with A and two carbon atoms to which A bonds, X represents a cyano group, and R1 and R2 represent hydrogen atoms, and Y5 represents a C1-C6 haloalkoxy group or a C1-C3 haloalkyl group.


<63> A method for producing a compound represented by the following Formula (65c), including reacting a compound represented by the following Formula (61e) according to <60> with an aldehyde:




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Wherein R2, A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5 have the same definitions as R2, A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5, respectively, in <1>.




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Wherein R1 represents a C1-C6 alkyl group which may have a substituent, a C1-C6 haloalkyl group which may have a substituent, or a benzyl group, and R2, A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5 represent the same definitions as R2, A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5, respectively, in <1>. In a case where K forms a benzene ring together with A and two carbon atoms to which A bonds, all X's represent hydrogen atoms, and R2 represents a hydrogen atom, Y5 represents a C1-C3 haloalkyl group.


<64> A method for producing a compound represented by the following Formula (1), including reacting a compound represented by the following Formula (65b) with a compound represented by the following Formula (62) according to <48>:




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Wherein R1, R2, A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5 have the same definitions as R1, R2, A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5, respectively, in <1>.





T-LG  Formula (62)


Wherein LG represents a functional group having a leaving ability, such as a halogen atom, a hydroxy group, or the like, and T has the same definition as T in <1>.




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<65> A compound represented by the following Formula (68):




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Wherein Xa represents a chlorine atom, a bromine atom, or an iodine atom, and R2, A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y have the same definitions as R2, A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5, respectively, in <23>.


<66> A method for producing a compound represented by the following Formula (68) according to <65>, including reacting a compound represented by the following Formula (57j) with a compound represented by the following Formula (67):




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Wherein R2, Y1, Y2, Y3, Y4, and Y5 have the same definitions as R2, Y1, Y2, Y3, Y4, and Y5, respectively, in <1>.




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Wherein LG represents a functional group having a leaving ability, such as a halogen atom, a hydroxy group, or the like, Xa represents a chlorine atom, a bromine atom, or an iodine atom, and A, K, X, n, and G3 have the same definitions as A, K, X, n, and G3, respectively, in <23>.




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Wherein Xa represents a chlorine atom, a bromine atom, or an iodine atom, and R2, A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5 have the same definitions as R2, A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5, respectively, in <23>.


<67> A method for producing a compound represented by the following Formula (65d), including reacting a compound represented by the following Formula (68) according to <65> with an aminating agent:




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Wherein Xa represents a chlorine atom, a bromine atom, or an iodine atom, and R2, A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5 have the same definitions as R2, A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5, respectively, in <23>.




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Wherein R1, R2, A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5 have the same definitions as R1, R2, A, K, X, n, G3, Y1, Y2, Y3, Y4, and Y5, respectively, in <23>.


<68> A compound represented by the following Formula (70):




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Wherein Xb represents a chlorine atom, a bromine atom, or an iodine atom, and R2, G3, Y1, Y2, Y3, Y4, and Y5 have the same definition as, respectively, in <1>.


<69> A compound represented by the following Formula (72):




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Wherein R2, G3, Y1, Y2, Y3, Y4, and Y5 have the same definitions as R2, G3, Y1, Y2, Y3, Y4, and Y5, respectively, in <1>.


<70> A method for producing a compound represented by the following Formula (72) according to <69>, including reacting a compound represented by Formula (70) according to <68> with a fluorinating agent:




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Wherein R2, G3, Y1, Y2, Y3, Y4, and Y5 have the same definitions as R2, G3, Y1, Y2, Y3, Y4, and Y5, respectively, in <1>.


<71> A compound represented by the following Formula (73):




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Wherein Xc represents a halogen atom, and R2, G3, Y1, Y2, Y3, Y4, and Y5 have the same definitions as R2, G3, Y1, Y2, Y3, Y4, and Y5, respectively, in <1>.


<72> A compound represented by the following Formula (75):




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Wherein Y represents a C1-C6 haloalkoxy group or a C1-C3 haloalkyl group, and R2, G3, Y1, Y2, Y3, and Y4 have the same definitions as R2, G3, Y1, Y2, Y3, and Y4, respectively, in <1>.


<73> A method for producing a compound represented by the following Formula (75) according to <72>, including reacting a compound represented by Formula (73) according to <71>, in which Y5 is a C1-C6 haloalkoxy group or a C1-C3 haloalkyl group, with a cyanating agent:




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Wherein Y5 represents a C1-C6 haloalkoxy group or a C1-C3 haloalkyl group, R2, G3, Y1, Y2, Y3, and Y4 have the same definitions as R2, G3, Y1, Y2, Y3, and Y4, respectively, in <1>.


<74> A compound represented by the following Formula (56a):




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Wherein Y5 represents a C1-C3 haloalkyl group, and Y2, Y3, and Y4 have the same definitions as Y2, Y3, and Y4, respectively, in <3>.


<75> A compound represented by the following Formula (57e):




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Wherein Y5 represents a C1-C3 haloalkyl group, and Y1, Y2, Y3, and Y4 have the same definitions as Y1, Y2, Y3, and Y4 according to <3>.


<76> The compound according to <75>, wherein in Formula (57e), Y1 is a halogen atom.


<77> A method for producing a compound represented by the following Formula (57f) according to <76>, including reacting a compound represented by Formula (56a) according to <74> with a halogenating agent:




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Wherein Y5 represents a C1-C3 haloalkyl group, Y2, Y3, and Y4 represent the same definitions as Y2, Y3, and Y4, respectively, in <3>, and Y1 represents a halogen atom.


<78> A compound represented by the following Formula (60b):




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Wherein X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5 have the same definitions as X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5, respectively, in <3>. In a case where X1, X2, X3, and X4 represent all hydrogen atoms, Y5 represents a C1-C3 haloalkyl group, and in a case where X2 represents a cyano group, and X1, X3, and X4 represent hydrogen atoms, Y5 represents a C1-C3 haloalkoxy group or a C1-C3 haloalkyl group.


<79> A method for producing a compound represented by the following Formula (60b) according to <78>, including reacting a compound represented by the following Formula (59a) with a compound represented by the following Formula (57g):




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Wherein LG represents a functional group having a leaving ability, such as a halogen atom, a hydroxy group, or the like, and X1, X2, X3, and X4 have the same definitions as X1, X2, X3, and X4 in <3>.




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Wherein Y1, Y2, Y3, Y4, and Y5 have the same definitions as Y1, Y2, Y3, Y4, and Y5, respectively, in <3>.




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Wherein X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5 have the same definitions as X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5, respectively, in <3>. In a case where X1, X2, X3, and X4 represent all hydrogen atoms, Y5 represents a C1-C3 haloalkyl group, and in a case where X2 represents a cyano group, and X1, X3, and X4 represent hydrogen atoms, Y5 represents a C1-C3 haloalkoxy group or a C1-C3 haloalkyl group.


<80> A compound represented by the following Formula (61f):




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Wherein X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5 have the same definitions as X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5, respectively, in <3>. In a case where X1, X2, X3, and X4 represent all hydrogen atoms, Y5 represents a C1-C3 haloalkyl group, and in a case where X2 represents a cyano group, and X1, X3, and X4 represent hydrogen atoms, Y5 represents a C1-C3 haloalkoxy group or a C1-C3 haloalkyl group.


<81> A method for producing a compound represented by the following Formula (61 f) according to <80>, including reacting a compound represented by a compound represented by Formula (60b) according to <78> in the presence of a reducing agent:




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Wherein X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5 have the same definitions as X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5, respectively, in <3>. In a case where X1, X2, X3, and X4 represent all hydrogen atoms, Y5 represents a C1-C3 haloalkyl group, and in a case where X2 represents a cyano group, and X1, X3, and X4 represent hydrogen atoms, Y represents a C1-C3 haloalkoxy group or a C1-C3 haloalkyl group.


<82> A compound represented by the following Formula (69a):




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Wherein Q1, X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5 have the same definitions as Q1, X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5, respectively, in <3>.


<83> A method for producing a compound represented by the following Formula (69a) according to <82>, including reacting a compound represented by the following Formula (61c) with a compound represented by the following Formula (62a):




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Wherein X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5 represent the same definitions as X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5, respectively, in <3>.




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Wherein LG represents a functional group having a leaving ability, such as a halogen atom, a hydroxy group, or the like, and Q1 represents the same definition as Q1 in <3>.




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Wherein Q1, X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5 represent the same definitions as Q1, X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5, respectively, in <3>.


<84> A compound represented by the following Formula (53a):




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Wherein Q1, R1, X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5 have the same definitions as Q1, R1, X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5, respectively, in <3>.


<85> A method for producing a compound represented by the following Formula (53b), including reacting a compound represented by the following Formula (69a) according to <82> with a compound represented by the following Formula (64a):




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Wherein Q1, X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5 have the same definitions as Q1, X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5, respectively, in <3>.





R1-LG  Formula (64a)


Wherein LG represents a functional group having a leaving ability, such as a halogen atom, a hydroxy group, or the like, and R1 represents a C1-C3 alkyl group.




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Wherein R1 has the same definition as R1 in Formula (64a), and Q1, X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5 have the same definitions as Q1, X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5, respectively, in <3>.


<86> A compound represented by the following Formula (57h):




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Wherein Y5 represents a C1-C3 haloalkoxy group or a C1-C3 haloalkyl group, R2 represents a C1-C3 alkyl group, and Y1, Y2, Y3, and Y4 have the same definitions as Y1, Y2, Y3, and Y4, respectively, in <3>.


<87> A method for producing a compound represented by the following Formula (57h) according to <86>, including reacting a compound represented by the following Formula (57l) with a compound represented by the following Formula (66a):




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Wherein Y5 represents a C1-C3 haloalkoxy group or a C1-C3 haloalkyl group, and Y1, Y2, Y3, and Y4 have the same definitions as Y1, Y2, Y3, and Y4, respectively, in <3>.





R2-LG  Formula (66a)


Wherein LG represents a functional group having a leaving ability, such as a halogen atom, a hydroxy group, or the like, and R2 represents a C1-C3 alkyl group.




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Wherein Y5 represents a C1-C3 haloalkoxy group or a C1-C3 haloalkyl group, R2 represents a C1-C3 alkyl group, and Y1, Y2, Y3, and Y4 have the same definitions as Y1, Y2, Y3, and Y4, respectively, in <3>.


<88> A method for producing a compound represented by the following Formula (57h) according to <86>, including reacting a compound represented by the following Formula (57l) according to <87> with an aldehyde:




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Wherein Y5 represents a C1-C3 haloalkoxy group or a C1-C3 haloalkyl group, and Y1, Y2, Y3, and Y4 have the same definitions as Y1, Y2, Y3, and Y4, respectively, in <3>.




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Wherein Y5 represents a C1-C3 haloalkoxy group or a C1-C3 haloalkyl group, R2 represents a C1-C3 alkyl group, and Y1, Y2, Y3, and Y4 have the same definitions as Y1, Y2, Y3, and Y4, respectively, in <3>.


<89> A compound represented by the following Formula (60c):




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Wherein R2 represents a C1-C3 alkyl group, and X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5 have the same definitions as X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5, respectively, in <3>.


<90> A method for producing a compound represented by the following Formula (60c) according to <89>, including reacting a compound represented by the following Formula (60d) with a compound represented by the following Formula (66a) according to <87>:




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Wherein X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5 have the same definitions as X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5, respectively, in <3>.





R2-LG  Formula (66a)


Wherein LG represents a functional group having a leaving ability, such as a halogen atom, a hydroxy group, or the like, and R2 represents a C1-C3 alkyl group.




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(Wherein R2 represents a C1-C3 alkyl group, and X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5 have the same definitions as X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5, respectively, in <3>.


<91> A method for producing a compound represented by the following Formula (60c) according to <89>, including reacting a compound represented by the following Formula (57i) with a compound represented by the following Formula (59a) according to <79>:




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Wherein R2 represents a C1-C3 alkyl group, and Y1, Y2, Y3, Y4, and Y5 have the same definitions as Y1, Y2, Y3, Y4, and Y5, respectively, in <3>.




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Wherein LG represents a functional group having a leaving ability, such as a halogen atom, a hydroxy group, or the like, X1, X2, X3, and X4 have the same definitions as X1, X2, X3, and X4 in <3>.




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Wherein R2 represents a C1-C3 alkyl group, and X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5 have the same definitions as X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5, respectively, in <3>.


<92> A compound represented by the following Formula (61g):




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Wherein R2 represents a C1-C3 alkyl group, and X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5 have the same definitions as X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5, respectively, in <3>.


<93> A method for producing a compound represented by the following Formula (61g) according to <92>, including reacting a compound represented by Formula (60c) according to <89> in the presence of a reducing agent:




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Wherein R2 represents a C1-C3 alkyl group, and X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5 have the same definitions as X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5, respectively, in <3>.


<94> A compound represented by the following Formula (63c):




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Wherein Q1, R2, X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5 have the same definitions as Q1, R2, X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5, respectively, in <3>.


<95> A method for producing a compound represented by the following Formula (63c) according to <94>, including reacting a compound represented by the following Formula (61d) with a compound represented by the following Formula (62a) according to <83>:




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Wherein R2, X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5 have the same definitions as R2, X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5, respectively, in <3>.




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Wherein LG represents a functional group having a leaving ability, such as a halogen atom, a hydroxy group, or the like, and Q1 has the same definition as Q1 in <3>.




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Wherein Q1, R2, X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5 have the same definitions as Q1, R2, X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5, respectively, in <3>.


<96> A method for producing a compound represented by the following Formula (3a), including reacting a compound represented by the following Formula (63c) according to <94> with a compound represented by the following Formula (64a) according to <85>:




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Wherein Q1, R2, X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5 have the same definitions as Q1, R2, X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5, respectively, in <3>.





R1-LG  Formula (64a)


Wherein LG represents a functional group having a leaving ability, such as a halogen atom, a hydroxy group, or the like, and R1 represents a C1-C3 alkyl group.




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Wherein R1 has the same definition as R1 in Formula (64a), and Q1, R2, X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5 have the same definitions as Q1, R2, X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5, respectively, in <3>.


<97> A compound represented by the following Formula (65e):




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Wherein R1, R2, X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5 have the same definitions as R1, R2, X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5, respectively, in <3>. In a case where X1, X2, X3, and X4, represent all hydrogen atoms, and R2 represents a hydrogen atom, Y5 represents a C1-C3 haloalkyl group, and in a case where X2 represents a cyano group, X1, X3, and X4 represent hydrogen atoms, and R1 and R2 represent hydrogen atoms, Y5 represents a C1-C3 haloalkoxy group or a C1-C3 haloalkyl group.


<98> A method for producing a compound represented by the following Formula (65f), including reacting a compound represented by the following Formula (61d) with an aldehyde:




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Wherein R2, X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5 have the same definitions as R2, X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5, respectively, in <3>.




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Wherein R1 represents a C1-C3 alkyl group, and R2, X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5 have the same definitions as R2, X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5, respectively, in <3>. In a case where X1, X2, X3, and X4 represent all hydrogen atoms, and R2 represents a hydrogen atom, Y5 represents a C1-C3 haloalkyl group.


<99> A method for producing a compound represented by the following Formula (3) according to <3>, including reacting a compound represented by the following Formula (65g) with a compound represented by the following Formula (62a) according to <83>:




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Wherein R1, R2, X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5 have the same definitions as R1, R2, X1, X2, X3, X4, Y1, Y2, Y3, Y4, and Y5, respectively, in <3>.




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Wherein LG represents a functional group having a leaving ability, such as a halogen atom, a hydroxy group, or the like, and Q1 has the same definition as Q1 in <3>.




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<100> A compound represented by the following Formula (70a):




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Wherein Xb represents a chlorine atom, a bromine atom, or an iodine atom, and R2, Y1, Y2, Y3, Y4, and Y5 have the same definitions as R2, Y1, Y2, Y3, Y4, and Y5, respectively, in <3>.


<101> A compound represented by the following Formula (72a):




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Wherein R2, Y1, Y2, Y3, Y4, and Y5 have the same definitions as R2, Y1, Y2, Y3, Y4, and Y5, respectively, in <3>.


<102> A method for producing a compound represented by the following Formula (72a) according to <101>, including reacting a compound represented by Formula (70a) according to <100> with a fluorinating agent:




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Wherein R2, Y1, Y2, Y3, Y4, and Y5 have the same definitions as R2, Y1, Y2, Y3, Y4, and Y5, respectively, in <3>.


<103> A composition for controlling a pest comprising as an active ingredient at least one amide derivative represented by the following Formula (A1):




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Wherein, in Formula (A1), Q1 represents a phenyl group or a phenyl group substituted with a halogen atom; X1 represents a fluorine atom; X2, X3, and X4 are each a hydrogen atom; R1 represents a hydrogen atom or a C1-C3 alkyl group; R2 is a hydrogen atom; Y1 and Y5 each independently represent a halogen atom or a C1-C3 haloalkyl group; Y2 and Y4 each represent a hydrogen atom; and Y3 represents a heptafluoroisopropyl group.


<104> The composition according to <103>, wherein the pest is an animal parasite.


<105> The composition according to <104>, wherein in Formula (A1), Q1 represents a phenyl group or a phenyl group substituted with a single fluorine atom; R1 represents a hydrogen atom or a methyl group; and Y1 and Y5 each independently represent a bromine or iodine atom or a trifluoromethyl group.


<106> The composition according to <105>, wherein the amide derivative represented by Formula (A1) is 2-fluoro-3-(N-methylbenzamide)-N-(2-bromo-6-trifluoromethyl-4-(heptafluoropropan-2-yl)phenyl)benzamide, 2-fluoro-3-(4-fluoro-N-methylbenzamide)-N-(2-iodo-6-trifluoromethyl-4-(heptafluoropropan-2-yl)phenyl)benzamide, 2-fluoro-3-(3-fluoro-N-methylbenzamide)-N-(2-iodo-6-trifluoromethyl-4-(heptafluoropropan-2-yl)phenyl)benzamide, 2-fluoro-3-(4-fluorobenzamide)-N-(2-iodo-6-trifluoromethyl-4-(heptafluoropropan-2-yl)phenyl)benzamide, or 2-fluoro-3-(N-methylbenzamide)-N-(2,6-dibromo-4-(heptafluoropropan-2-yl)phenyl)benzamide.


<107> A method for exterminating animal parasites, comprising administering to an animal the composition according to <104> to <106>.


<108> The method according to <107>, wherein the animal parasite is an ectoparasite.


<109> The method according to <108>, wherein the ectoparasite is Siphonaptera pests.


<110> The method according to <108>, wherein the ectoparasite is Acarina pests.


According to the present invention, an amide derivative showing a pesticidal effect against a wide range of agricultural/horticultural pests, a pest control agent containing the amide derivative as an active ingredient, and a pest controlling method are provided.







DETAILED DESCRIPTION OF THE INVENTION

An amide compound according to the present invention is represented by the following Formula (1).




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In Formula (1), A represents a carbon atom, an oxygen atom, a nitrogen atom, an oxidized nitrogen atom, or a sulfur atom. K represents a non-metal atom group necessary for forming a cyclic linking group derived from benzene, pyridine, pyridine-N-oxide, pyrimidine, pyrazine, pyridazine, triazine, pyrrole, pyrazole, imidazole, oxazole, isoxazole, thiazole, isothiazole, furan, thiophene, oxadiazole, thiodiazole, or triazole, in combination with A and two carbon atoms to which A bonds.


X represents a hydrogen atom, a halogen atom, a C1-C6 alkyl group, a C1-C6 haloalkyl group, a C3-C9 cycloalkyl group, a C3-C9 halocycloalkyl group, a C2-C6 alkenyl group, a C2-C6 haloalkenyl group, a C2-C6 alkynyl group, a C2-C6 haloalkynyl group, a C1-C6 alkoxy group, a C1-C6 haloalkoxy group, a C1-C6 alkylthio group, a C1-C6 haloalkylthio group, a C1-C6 alkylsulfinyl group, a C1-C6 haloalkylsulfinyl group, a C1-C6 alkylsulfonyl group, a C1-C6 haloalkylsulfonyl group, a C1-C6 alkylsulfonyloxy group, a C1-C6 haloalkylsulfonyloxy group, a C2-C7 alkylcarbonyl group, a C2-C7 haloalkylcarbonyl group, a C2-C7 alkylcarbonyloxy group, a C2-C7 haloalkylcarbonyloxy group, arylcarbonyloxy group, a C2-C7 alkoxycarbonyl group, a C2-C7 haloalkoxycarbonyl group, a C2-C7 alkylcarbonylamino group, a C2-C7 haloalkylcarbonylamino group, a C2-C7 alkoxycarbonylamino group, a C2-C7 haloalkoxycarbonylamino group, a C2-C7 alkoxycarbonyloxy group, a C2-C7 haloalkoxycarbonyloxy group, an arylcarbonylamino group, an amino group, a carbamoyl group, a cyano group, a hydroxy group, pentafluorosulfanyl group, a C1-C6 alkylamino group, a C1-C6 haloalkylamino group, a C2-C6 alkenylamino group, a C2-C6 haloalkenylamino group, a C2-C6 alkynylamino group, a C2-C6 haloalkynylamino group, a C3-C9 cycloalkylamino group, a C3-C9 halocycloalkylamino group, a C2-C7 alkylaminocarbonyl group, a C2-C7 haloalkylaminocarbonyl group, a C3-C7 alkenylaminocarbonyl group, a C3-C7 haloalkenylaminocarbonyl group, a C3-C7 alkynylaminocarbonyl group, a C3-C7 haloalkynylaminocarbonyl group, a C4-C10 cycloalkylaminocarbonyl group, a C4-C10 halocycloalkylaminocarbonyl group, a phenyl group, or a heterocyclic group, and when there are plural X's, each X may be the same as or different from an other.


n represents an integer of from 0 to 4. T represents —C(=G1)-Q1 or —C(=G1)-G2Q2. G1 and G2 each independently represent an oxygen atom or a sulfur atom, and Q1 and Q2 represent a hydrogen atom, a C1-C6 alkyl group, a C1-C6 haloalkyl group, a C2-C6 alkenyl group, a C2-C6 haloalkenyl group, a C2-C6 alkynyl group, a C2-C6 haloalkynyl group, a C3-C9 cycloalkyl group, a C3-C9 halocycloalkyl group, a benzyl group, a phenyl group which may have a substituent, a naphthyl group, or a heterocyclic group which may have a substituent.


Y1 and Y5 each independently represent a halogen atom, a C1-C6 haloalkoxy group, or a C1-C3 haloalkyl group, Y2 and Y4 each independently represent a hydrogen atom, a halogen atom, or a C1-C4 alkyl group, Y3 represents a C2-C5 haloalkyl group.


Further, in Q1 and Q2, the substituent of a phenyl group which may have a substituent and a heterocyclic group which may have a substituent represents one or more substituent selected from a group consisting of a halogen atom, a C1-C6 alkyl group, a C1-C6 haloalkyl group, a C3-C9 cycloalkyl group, a C3-C9 halocycloalkyl group, a C2-C6 alkenyl group, a C2-C6 haloalkenyl group, a C2-C6 alkynyl group, a C2-C6 haloalkynyl group, a C1-C6 alkoxy group, a C1-C6 haloalkoxy group, a C1-C6 alkylthio group, a C1-C6 haloalkylthio group, a C1-C6 alkylsulfinyl group, a C1-C6 haloalkylsulfinyl group, a C1-C6 alkylsulfonyl group, a C1-C6 haloalkylsulfonyl group, a C2-C7 alkylcarbonyl group, a C2-C7 haloalkylcarbonyl group, a C2-C7 alkylcarbonyloxy group, a C2-C7 haloalkylcarbonyloxy group, a C1-C6 alkylsulfonyloxy group, a C1-C6 haloalkylsulfonyloxy group, a C2-C7 alkoxycarbonyl group, a C2-C7 haloalkoxycarbonyl group, a C2-C7 alkylcarbonylamino group, a C2-C7 haloalkylcarbonylamino group, a C2-C7 alkoxycarbonylamino group, a C2-C7 haloalkoxycarbonylamino group, a C1-C6 alkylamino group, a C1-C6 haloalkylamino group, a C2-C6 alkenylamino group, a C2-C6 haloalkenylamino group, a C2-C6 alkynylamino group, a C2-C6 haloalkynylamino group, a C3-C9 cycloalkylamino group, a C3-C9 halocycloalkylamino group, a C2-C7 alkylaminocarbonyl group, a C2-C7 haloalkylaminocarbonyl group, a C3-C7 alkenylaminocarbonyl group, a C3-C7 haloalkenylaminocarbonyl group, a C3-C7 alkynylaminocarbonyl group, a C3-C7 haloalkynylaminocarbonyl group, a C4-C10 cycloalkylaminocarbonyl group, a C4-C10 halocycloalkylaminocarbonyl group, an amino group, a carbamoyl group, a cyano group, a nitro group, a hydroxy group, pentafluorosulfanyl group, a phenyl group which may have a substituent, and a heterocyclic group which may have a substituent, and when there are two or more substituents, each substituent may be the same as or different from each other.


Moreover, the heterocyclic group in X, Q1, and Q2 represent a pyridyl group, a pyridine-N-oxide group, a pyrimidinyl group, a pyrazinyl group, a pyridazyl group, furyl group, thienyl group, an oxazolyl group, an isoxazolyl group, an oxadiazolyl group, a thiazolyl group, an isothiazolyl group, a thiadiazolyl group, a pyrrolyl group, an imidazolyl group, a triazolyl group, a pyrazolyl group, or a tetrazolyl group.


G3 represents an oxygen atom or a sulfur atom.


R1 and R2 each independently represent a hydrogen atom, an oxygen atom, a halogen atom, a hydroxy group, a nitro group, a nitroso group, a trimethylsilyl group, a t-butyldimethylsilyl group, a cyano group, an amino group, a C1-C6 alkyl group which may have a substituent, a C1-C6 haloalkyl group which may have a substituent, a C2-C7 alkylcarbonyl group, a C2-C7 haloalkylcarbonyl group, a C2-C6 alkenyl group which may have a substituent, a C2-C6 haloalkenyl group which may have a substituent, a C2-C6 alkynyl group which may have a substituent, a C2-C6 haloalkynyl group which may have a substituent, a C2-C7 alkoxycarbonyl group, a C2-C7 haloalkoxycarbonyl group, a C3-C7 alkenyloxycarbonyl group, a C3-C7 haloalkenyloxycarbonyl group, a C3-C7 alkynyloxycarbonyl group, a C3-C7 haloalkynyloxycarbonyl group, a phenoxycarbonyl group, a C2-C7 alkylaminocarbonyl group, a C2-C7 haloalkylaminocarbonyl group, a C2-C7 alkylcarbonyloxy group, a C2-C7 haloalkylcarbonyloxy group, a benzoyl group, a C1-C6 alkoxy group, a C1-C6 haloalkoxy group, a C1-C6 alkylthio group, a C1-C6 haloalkylthio group, a C1-C6 alkylsulfinyl group, a C1-C6 haloalkylsulfinyl group, a C1-C6 alkylsulfonyl group, a C1-C6 haloalkylsulfonyl group, a benzenesulfonyl group, a benzylsulfonyl group, a benzyl group, or —C(═O)C(═O)R7 (wherein R7 represents a C1-C6 alkyl group, a C1-C6 haloalkyl group, a C1-C6 alkoxy group, or a C1-C6 haloalkoxy group).


However the amide derivative represented by Formula (1) is not one of (A) to (I):


(A) A case where in Formula (1), K represents a non-metal atom group necessary for forming a cyclic linking group derived from pyridine in combination with A and two carbon atoms to which A bonds, Y1 represents a halogen atom, and Y5 represents a C1-C6 haloalkoxy group, and T is —C(=G1)-Q1.


(B) A case where in Formula (1), K represents a non-metal atom group necessary for forming a cyclic linking group derived from pyrrole, pyrazole, imidazole, oxazole, isoxazole, thiazole, isothiazole, furan, thiophene, oxadiazole, thiodiazole, or triazole, in combination with A and two carbon atoms to which A bonds, Y1 and Y5 represent each independently a halogen atom, and T is —C(=G1)-G2Q2.


(C) A case where in Formula (1), K represents a non-metal atom group necessary for forming a cyclic linking group derived from pyrrole, pyrazole, imidazole, oxazole, isoxazole, thiazole, isothiazole, furan, thiophene, oxadiazole, thiodiazole, or triazole, in combination with A and two carbon atoms to which A bonds, T represents —C(=G1)-Q1, Y1 is a halogen atom, and Y5 represents a halogen atom or a haloalkoxy group.


(D) A case where the amide derivative is an amide compound represented by the following Formula (2):




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In Formula (2), Y2 to Y4, Q1, G1, G3, R1, and R2 have the same definitions as Y2 to Y4, Q1, G1, G3, R1, and R2, respectively, in Formula (1), Y1 represents a halogen atom, and Y5 represents a C1-C2 haloalkoxy group.


(E) A case where in Formula (2), Y1 and Y5 represent halogen atoms, all X's represent hydrogen atoms, and Y3 represents a C2-C3 haloalkyl group.


(F) A case where the amide derivative is an amide derivative represented by the following Formula (3)




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In Formula (3), Y1 and Y5 each independently represent a halogen atom, X1 and X3 each independently represent a hydrogen atom or a fluorine atom, Q1 has the same definition as Q1 in Formula (1), R1 represents a hydrogen atom or a methyl group, and Y3 represents a C3-C4 perfluoroalkyl group.


(G) A case where the amide derivative is an amide derivative represented by the following Formula (4):




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In Formula (4), X1 represents a fluorine atom, X2, X3, and X4 represent hydrogen atoms, Y1 and Y5 are different from each other and represent a bromine atom or a trifluoromethoxy group, Y2 and Y4 represent hydrogen atoms, Y3 represents a heptafluoroisopropyl group, Q1 represents a phenyl group or a 2-chloropyridin-3-yl group, and R1 and R2 are different from each other, and represent a hydrogen atom or a methyl group.


Alternatively, X1 represents a fluorine atom, X2, X3, and X4 represent hydrogen atoms, Y1 and Y5 represent bromine atoms, Y2 and Y4 represent hydrogen atoms, Y3 represents a pentafluoroethyl group, Q1 represents a 2-fluorophenyl group, and R1 and R2 each independently represent a hydrogen atom or a methyl group.


(H) A case where the amide derivative is an amide derivative represented by the following Formula (5):




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In Formula (5), Y1 and Y5 each independently represent a halogen atom, X1 represents a hydrogen atom or a fluorine atom, Q2 represents a 2,2,2-trichloroethyl group or a 3,3,3-trifluoro-n-propyl group, and Y3 represents a C2-C4 haloalkyl group.


(I) A case where the amide derivative is an amide derivative represented by the following Formula (6)




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In Formula (6), Y1 and Y5 each independently represent a halogen atom, Q2 has the same definition as Q2 in Formula (1), R1 represents a hydrogen atom or a methyl group, and Y3 represents a C3-C4 haloalkyl group


In the aspect of a pest control activity, the amide derivative preferably represented by the following Formula (7), and more preferably represented by the following Formula (8).




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In Formula (7), X, n is 4, Y1 to Y5, Q1, G1, G3, R1, and R2 have the same definitions as X, Y1 to Y5, Q1, G1, G3, R1, and R2, respectively, in Formula (1).




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In Formula (8), Q1 represents a phenyl group which may have a substituent or a pyridyl group which may have a substituent. X1, X2, X3 and X4 each independently represent hydrogen atoms or fluorine atoms. R1 and R2 each independently represent hydrogen atoms or C1-C3 alkyl groups.


Y1 and Y5 each independently represent halogen atoms, C1-C3 haloalkoxyl groups, or C1-C3 haloalkyl groups, Y2 and Y4 each independently represent hydrogen atoms, halogen atoms, C1-C4 alkyl groups, and Y3 represents a C3-C4 haloalkyl group.


In a case where Y1 and Y5 represent halogen atoms simultaneously, at least one of X1 and X2 represents a fluorine atom. Further, in a case where Y1 or Y5 represents a C1-C3 haloalkoxy group, X2 represents a fluorine atom.


The terms used in the formulae including the Formula (1) and the like according to the present invention, have the same meanings as described below in the definitions.


The “halogen atom” represents a fluorine atom, a chlorine atom, a bromine atom, or an iodine atom.


The expression “Ca-Cb (wherein a and b represent an integer of 1 or more)”, for example, “C1-C3” means the number of carbon atoms of from 1 to 3, the “C2-C6” means the number of carbon atoms of from 2 to 6, and the “C1-C4” means the number of carbon atoms of from 1 to 4.


“n-” means normal, “i-” means iso, “s-” means secondary, and “t-” means tertiary.


The “C1-C3 alkyl group” in the present invention represents, for example, a linear or branched alkyl group having from 1 to 3 carbon atoms such as methyl, ethyl, n-propyl, i-propyl, and the like.


The “C1-C3 haloalkyl group” represents, for example, a linear or branched alkyl group having from 1 to 3 carbon atoms, that is substituted with one or more halogen atoms which may be the same as or different from each other, such as trifluoromethyl, pentafluoroethyl, heptafluoro-n-propyl, heptafluoro-i-propyl, 2,2-difluoroethyl, 2,2-dichloroethyl, 2,2,2-trifluoroethyl, 2-fluoroethyl, 2-chloroethyl, 2-bromoethyl, 2-iodoethyl, 2,2,2-trichloroethyl, 2,2,2-tribromoethyl, 1,3-difluoro-2-propyl, 1,3-dichloro-2-propyl, 1-chloro-3-fluoro-2-propyl, 1,1,1-trifluoro-2-propyl, 2,3,3,3-trifluoro-n-propyl, 1,1,1,3,3,3-hexafluoro-2-propyl, 1,1,1,3,3,3-hexafluoro-2-chloro-2-propyl, 1,1,1,3,3,3-hexafluoro-2-bromo-2-propyl, 1,1,2,3,3,3-hexafluoro-2-chloro-n-propyl, 1,1,2,3,3,3-hexafluoro-2-bromo-n-propyl, 1,1,2,3,3,3-hexafluoro-1-bromo-2-propyl, 2,2,3,3,3-pentafluoro-n-propyl, 3-fluoro-n-propyl, 3-chloro-n-propyl, 3-bromo-n-propyl, and the like.


The “C1-C4 alkyl group” represents, for example, a linear or branched alkyl group having from 1 to 4 carbon atoms such as methyl, ethyl, n-propyl, i-propyl, n-butyl, s-butyl, t-butyl, and the like.


The “C1-C3 haloalkoxy group” represents, for example, a linear or branched alkoxy group having from 1 to 3 carbon atoms, that is substituted with one or more halogen atoms which may be the same as or different from each other, such as trifluoromethoxy, pentafluoroethoxy, heptafluoro-n-propyloxy, heptafluoro-i-propyloxy, 2,2-difluoroethoxy, 2,2-dichloroethoxy, 2,2,2-trifluoroethoxy, 2-fluoroethoxy, 2-chloroethoxy, 2-bromoethoxy, 2-iodoethoxy, 2,2,2-trichloroethoxy, 2,2,2-tribromoethoxy, 1,3-difluoro-2-propyloxy, 1,3-dichloro-2-propyloxy, 1-chloro-3-fluoro-2-propyloxy, 1,1,1-trifluoro-2-propyloxy, 2,3,3,3-trifluoro-n-propyloxy, 1,1,1,3,3,3-hexafluoro-2-propyloxy, 1,1,1,3,3,3-hexafluoro-2-chloro-2-propyloxy, 1,1,1,3,3,3-hexafluoro-2-bromo-2-propyloxy, 1,1,2,3,3,3-hexafluoro-2-chloro-n-propyloxy, 1,1,2,3,3,3-hexafluoro-2-bromo-n-propyloxy, 1,1,2,3,3,3-hexafluoro-1-bromo-2-propyloxy, 2,2,3,3,3-pentafluoro-n-propyloxy, 3-fluoro-n-propyloxy, 3-chloro-n-propyloxy, 3-bromo-n-propyloxy, and the like.


The “C3-C4 perfluoroalkyl group” represents, for example, a linear or branched alkyl group having from 3 to 4 carbon atoms, that all hydrogen atoms is substituted with fluorine atoms such as perfluoro-n-propyl, perfluoro-i-propyl, perfluoro-n-butyl, perfluoro-i-butyl, perfluoro-s-butyl, perfluoro-t-butyl, and the like.


The “C1 haloalkyl group” represents, for example, a methyl group that is substituted with one or more halogen atoms which may be the same as or different from each other, such as trifluoromethyl, 1,1-difluoro-1-bromomethyl, and the like.


The “C1-C6 alkyl group” in the present invention represents, for example, a linear or branched alkyl group having from 1 to 6 carbon atoms such as methyl, ethyl, n-propyl, i-propyl, n-butyl, s-butyl, t-butyl, n-pentyl, 2-pentyl, neopentyl, 4-methyl-2-pentyl, n-hexyl, 3-methyl-n-pentyl, and the like.


The “C1-C6 haloalkyl group” represents, for example, a linear or branched alkyl group having from 1 to 6 carbon atoms, that is substituted with one or more halogen atoms which may be the same as or different from each other, such as trifluoromethyl, pentafluoroethyl, heptafluoro-n-propyl, heptafluoro-i-propyl, 2,2-difluoroethyl, 2,2-dichloroethyl, 2,2,2-trifluoroethyl, 2-fluoroethyl, 2-chloroethyl, 2-bromoethyl, 2-iodoethyl, 2,2,2-trichloroethyl, 2,2,2-tribromoethyl, 1,3-difluoro-2-propyl, 1,3-dichloro-2-propyl, 1-chloro-3-fluoro-2-propyl, 1,1,1-trifluoro-2-propyl, 2,3,3,3-trifluoro-n-propyl, 4,4,4-trifluoro-n-butyl, 1,1,1,3,3,3-hexafluoro-2-propyl, 1,1,1,3,3,3-hexafluoro-2-chloro-2-propyl, 1,1,1,3,3,3-hexafluoro-2-bromo-2-propyl, 1,1,2,3,3,3-hexafluoro-2-chloro-n-propyl, 1,1,2,3,3,3-hexafluoro-2-bromo-n-propyl, 1,1,2,3,3,3-hexafluoro-1-bromo-2-propyl, 2,2,3,3,3-pentafluoro-n-propyl, 3-fluoro-n-propyl, 3-chloro-n-propyl, 3-bromo-n-propyl, 3,3,4,4,4-pentafluoro-2-butyl, nonafluoro-n-butyl, nonafluoro-2-butyl, 5,5,5-trifluoro-n-pentyl, 4,4,5,5,5-pentafluoro-2-pentyl, 3-chloro-n-pentyl, 4-bromo-2-pentyl, and the like.


The “C3-C9 cycloalkyl group” represents, for example, a cycloalkyl group having from 3 to 9 carbon atoms, that has a cyclic structure, such as cyclopropyl, cyclobutyl, cyclopentyl, 2-methylcyclopentyl, 3-methylcyclopentyl, cyclohexyl, 2-methylcyclohexyl, 3-methylcyclohexyl, 4-methylcyclohexyl, and the like.


The “C3-C9 halocycloalkyl group” represents, for example, a cycloalkyl group having 3 to 9 carbon atoms, that is substituted with one or more halogen atoms which may be the same as or different from each other and has a cyclic structure, such as, 2,2,3,3-tetrafluorocyclobutyl, 2-chlorocyclohexyl, 4-chlorocyclohexyl, and the like.


The “C2-C6 alkenyl group” represents, for example, an alkenyl group having from 2 to 6 carbon atoms, that has a double bond in the carbon chain, such as vinyl, allyl, 2-butenyl, 3-butenyl, and the like.


The “C2-C6 haloalkenyl group” represents, for example, a linear or branched alkenyl group having from 2 to 6 carbon atoms, that is substituted with one or more halogen atoms which may be the same as or different from each other and has a double bond in the carbon chain, such as 3,3-difluoro-2-propenyl, 3,3-dichloro-2-propenyl, 3,3-dibromo-2-propenyl, 2,3-dibromo-2-propenyl, 4,4-difluoro-3-butenyl, 3,4,4-tribromo-3-butenyl, and the like.


The “C2-C6 alkynyl group” represents, for example, an alkynyl group having from 2 to 6 carbon atoms, that has a triple bond in the carbon chain, such as propargyl, 1-butyn-3-yl, 1-butyn-3-methyl-3-yl, and the like.


The “C2-C6 haloalkynyl group” represents, for example, a linear or branched alkynyl group having from 2 to 6 carbon atoms, that is substituted with one or more halogen atoms which may be the same as or different from each other and has a triple bond in the carbon chain, such as fluoroethynyl, chloroethynyl, bromoethynyl, 3,3,3-trifluoro-1-propynyl, 3,3,3-trichloro-1-propynyl, 3,3,3-tribromo-1-propynyl, 4,4,4-trifluoro-1-butynyl, 4,4,4-trichloro-1-butynyl, 4,4,4-tribromo-1-butynyl, and the like.


The “C1-C6 alkoxy group” represents, for example, a linear, branched, or cyclic alkoxy group having from 1 to 6 carbon atoms, such as methoxy, ethoxy, n-propyloxy, i-propyloxy, cyclopropoxy, n-butoxy, s-butoxy, i-butoxy, t-butoxy, n-pentyloxy, i-pentyloxy, n-hexyloxy, cyclohexyloxy, and the like.


The “C1-C6 haloalkoxy group” represents, for example, a linear, branched, or cyclic alkoxy group having from 1 to 6 carbon atoms, that is substituted with one or more halogen atoms which may be the same as or different from each other, such as trifluoromethoxy, pentafluoroethoxy, 2-chloroethoxy, 2,2,2-trifluoroethoxy, heptafluoro-n-propoxy, heptafluoro-i-propoxy, 1,1,1,3,3,3-hexafluoro-2-propoxy, 3-fluoro-n-propoxy, 1-chlorocyclopropoxy, 2-bromocyclopropoxy, 3,3,4,4,4-pentafluoro-2-butoxy, nonafluoro-n-butoxy, nonafluoro-2-butoxy, 5,5,5-trifluoro-n-pentyloxy, 4,4,5,5,5-pentafluoro-2-pentyloxy, 3-chloro-n-pentyloxy, 4-bromo-2-pentyloxy, 4-chlorobutyloxy, 2-iodo-n-propyloxy, and the like.


The “C1-C6 alkylthio group” represents, for example, a linear, branched, or cyclic alkylthio group having from 1 to 6 carbon atoms, such as methylthio, ethylthio, n-propylthio, i-propylthio, cyclopropylthio, n-butylthio, s-butylthio, i-butylthio, t-butylthio, n-pentylthio, i-pentylthio, n-hexylthio, cyclohexylthio, and the like.


The “C1-C6 haloalkylthio group” represents, for example, a linear, branched, or cyclic alkylthio group having from 1 to 6 carbon atoms, that is substituted with one or more halogen atoms which may be the same as or different from each other, such as trifluoromethylthio, pentafluoroethylthio, 2-chloroethylthio, 2,2,2-trifluoroethylthio, heptafluoro-n-propylthio, heptafluoro-i-propylthio, 1,1,1,3,3,3-hexafluoro-2-propylthio, 3-fluoro-n-propylthio, 1-chlorocyclopropylthio, 2-bromocyclopropylthio, 3,3,4,4,4-pentafluoro-2-butylthio, nonafluoro-n-butylthio, nonafluoro-2-butylthio, 5,5,5-trifluoro-n-pentylthio, 4,4,5,5,5-pentafluoro-2-pentylthio, 3-chloro-n-pentylthio, 4-bromo-2-pentylthio, 4-chlorobutylthio, 2-iodo-n-propylthio, and the like.


The “C1-C6 alcylsulfinyl group” represents, for example, a linear, branched, or cyclic alkylsulfinyl group having from 1 to 6 carbon atoms, such as methylsulfinyl, ethylsulfinyl, n-propylsulfinyl, i-propylsulfinyl, cyclopropylsulfinyl, n-butylsulfinyl, s-butylsulfinyl, i-butylsulfinyl, t-butylsulfinyl, n-pentylsulfinyl, i-pentylsulfinyl, n-hexylsulfinyl, cyclohexylsulfinyl, and the like.


The “C1-C6 haloalkylsulfinyl group” represents, for example, a linear, branched, or cyclic alkylsulfinyl group having from 1 to 6 carbon atoms, that is substituted with one or more halogen atoms which may be the same as or different from each other, such as trifluoromethylsulfinyl, pentafluoroethylsulfinyl, 2-chloroethylsulfnyl, 2,2,2-trifluoroethylsulfinyl, heptafluoro-n-propylsulfinyl, heptafluoro-i-propylsulfinyl, 1,1,1,3,3,3-hexafluoro-2-propylsulfinyl, 3-fluoro-n-propylsulfinyl, 1-chlorocyclopropylsulfinyl, 2-bromocyclopropylsulfinyl, 3,3,4,4,4-pentafluoro-2-butylsulfinyl, nonafluoro-n-butylsulfinyl, nonafluoro-2-butylsulfinyl, 5,5,5-trifluoro-n-pentylsulfinyl, 4,4,5,5,5-pentafluoro-2-pentylsulfinyl, 3-chloro-n-pentylsulfinyl, 4-bromo-2-pentylsulfinyl, 4-chlorobutylsulfinyl, 2-iodo-n-propylsulfinyl, and the like.


The “C1-C6 alkylsulfonyl group” represents, for example, a linear, branched, or cyclic alkylsulfonyl group having from 1 to 6 carbon atoms, such as methylsulfonyl, ethylsulfonyl, n-propylsulfonyl, i-propylsulfonyl, cyclopropylsulfonyl, n-butylsulfonyl, s-butylsulfonyl, i-butylsulfonyl, t-butylsulfonyl, n-pentylsulfonyl, i-pentylsulfonyl, n-hexylsulfonyl, cyclohexylsulfonyl, and the like.


The “C1-C6 haloalkylsulfonyl group” represents, for example, a linear, branched, or cyclic alkylsulfonyl group having from 1 to 6 carbon atoms, that is substituted with one or more halogen atoms which may be the same as or different from each other, such as trifluoromethylsulfonyl, pentafluoroethylsulfonyl, 2-chloroethylsulfonyl, 2,2,2-trifluoroethylsulfonyl, heptafluoro-n-propylsulfonyl, heptafluoro-i-propylsulfonyl, 1,1,1,3,3,3-hexafluoro-2-propylsulfonyl, 3-fluoro-n-propylsulfonyl, 1-chlorocyclopropylsulfonyl, 2-bromocyclopropylsulfonyl, 3,3,4,4,4-pentafluoro-2-butylsulfonyl, nonafluoro-n-butylsulfonyl, nonafluoro-2-butylsulfonyl, 5,5,5-trifluoro-n-pentylsulfonyl, 4,4,5,5,5-pentafluoro-2-pentylsulfonyl, 3-chloro-n-pentylsulfonyl, 4-bromo-2-pentylsulfonyl, 4-chlorobutylsulfonyl, 2-iodo-n-propylsulfonyl, and the like.


The “C1-C6 alkylsulfonyloxy group” represents, for example, a linear, branched, or cyclic alkylsulfonyloxy group having from 1 to 6 carbon atoms, such as methanesulfonyloxy, ethanesulfonyloxy, n-propanesulfonyloxy, i-propanesulfonyloxy, cyclopropanesulfonyloxy, n-butanesulfonyloxy, s-butanesulfonyloxy, i-butanesulfonyloxy, t-butanesulfonyloxy, n-pentanesulfonyloxy, i-pentanesulfonyloxy, n-hexanesulfonyloxy, cyclohexanesulfonyloxy, and the like.


The “C1-C6 haloalkylsulfonyloxy group” represents, for example, a linear, branched, or cyclic alkylsulfonyloxy group having from 1 to 6 carbon atoms, that is substituted with one or more halogen atoms which may be the same as or different from each other, such as trifluoromethanesulfonyloxy, pentafluoropropanesulfonyloxy, 2-chloropropanesulfonyloxy, 2,2,2-trifluoropropanesulfonyloxy, heptafluoro-n-propanesulfonyloxy, heptafluoro-i-propanesulfonyloxy, 1,1,1,3,3,3-hexafluoro-2-propanesulfonyloxy, 3-fluoro-n-propanesulfonyloxy, 1-chlorocyclopropanesulfonyloxy, 2-bromocyclopropanesulfonyloxy, 3,3,4,4,4-pentafluoro-2-butanesulfonyloxy, nonafluoro-n-butanesulfonyloxy, nonafluoro-2-butanesulfonyloxy, 5,5,5-trifluoro-n-pentanesulfonyloxy, 4,4,5,5,5-pentafluoro-2-pentanesulfonyloxy, 3-chloro-n-pentanesulfonyloxy, 4-bromo-2-pentanesulfonyloxy, 4-chlorobutanesulfonyloxy, 2-iodo-n-propanesulfonyloxy, and the like.


The “C2-C7 alkylcarbonyl group” represents, for example, a linear, branched, or cyclic alkylcarbonyl group having from 2 to 7 carbon atoms, such as acetyl, propionyl, i-propylcarbonyl, cyclopropylcarbonyl, n-butylcarbonyl, s-butylcarbonyl, t-butylcarbonyl, n-pentylcarbonyl, 2-pentylcarbonyl, neopentylcarbonyl, cyclopentylcarbonyl, and the like.


The “C2-C7 haloalkylcarbonyl group” represents, for example, a linear, branched, or cyclic alkylcarbonyl group having from 2 to 7 carbon atoms, that is substituted with one or more halogen atoms which may be the same as or different from each other, such as trifluoroacetyl, pentafluoropropionyl, 2-chloropropionyl, 2,2,2-trifluoropropionyl, heptafluoro-n-propylcarbonyl, heptafluoro-i-propylcarbonyl, 1,1,1,3,3,3-hexafluoro-2-propylcarbonyl, 3-fluoro-n-propylcarbonyl, 1-chlorocyclopropylcarbonyl, 2-bromocyclopropylcarbonyl, 3,3,4,4,4-pentafluoro-2-butylcarbonyl, nonafluoro-n-butylcarbonyl, nonafluoro-2-butylcarbonyl, 5,5,5-trifluoro-n-pentylcarbonyl, 4,4,5,5,5-pentafluoro-2-pentylcarbonyl, 3-chloro-n-pentylcarbonyl, 4-bromo-2-pentylcarbonyl, 4-chlorobutylcarbonyl, 2-iodo-n-propylcarbonyl, and the like.


The “C2-C7 alkylcarbonyloxy group” represents, for example, a linear, branched, or cyclic alkylcarbonyloxy group having from 2 to 7 carbon atoms, such as acetyloxy, propionyloxy, i-propylcarbonyloxy, cyclopropylcarbonyloxy, n-butylcarbonyloxy, s-butylcarbonyloxy, t-butylcarbonyloxy, n-pentylcarbonyloxy, 2-pentylcarbonyloxy, neopentylcarbonyloxy, cyclopentylcarbonyloxy, and the like.


The “C2-C7 haloalkylcarbonyloxy group” represents, for example, a linear, branched, or cyclic alkylcarbonyloxy group having from 2 to 7 carbon atoms, that is substituted with one or more halogen atoms which may be the same as or different from each other, such as trifluoroacetyloxy, pentafluoropropionyloxy, 2-chloropropionyloxy, 2,2,2-trifluoropropionyloxy, heptafluoro-n-propylcarbonyloxy, heptafluoro-i-propylcarbonyloxy, 1,1,1,3,3,3-hexafluoro-2-propylcarbonyloxy, 3-fluoro-n-propylcarbonyloxy, 1-chlorocyclopropylcarbonyloxy, 2-bromocyclopropylcarbonyloxy, 3,3,4,4,4-pentafluoro-2-butylcarbonyloxy, nonafluoro-n-butylcarbonyloxy, nonafluoro-2-butylcarbonyloxy, 5,5,5-trifluoro-n-pentylcarbonyloxy, 4,4,5,5,5-pentafluoro-2-pentylcarbonyloxy, 3-chloro-n-pentylcarbonyloxy, 4-bromo-2-pentylcarbonyloxy, 4-chlorobutylcarbonyloxy, 2-iodo-n-propylcarbonyloxy, and the like.


The “C2-C7 alkoxycarbonyl group” represents, for example, a linear, branched, or cyclic alkoxycarbonyl group having from 2 to 7 carbon atoms, such as methoxycarbonyl, ethoxycarbonyl, isopropoxycarbonyl, cyclopropoxycarbonyl, n-butoxycarbonyl, s-butoxycarbonyl, t-butoxycarbonyl, n-pentyloxycarbonyl, 2-pentyloxycarbonyl, neopentyloxycarbonyl, cyclopentyloxycarbonyl, and the like.


The “C2-C7 haloalkoxycarbonyl group” represents, for example, a linear, branched, or cyclic alkoxycarbonyl group having from 2 to 7 carbon atoms, that is substituted with one or more halogen atoms which may be the same as or different from each other, such as trifluoromethoxycarbonyl, pentafluoroethoxycarbonyl, 2-chloroethoxycarbonyl, 2,2,2-trifluoroethoxycarbonyl, heptafluoro-n-propoxycarbonyl, heptafluoro-i-propoxycarbonyl, 1,1,1,3,3,3-hexafluoro-2-propoxycarbonyl, 3-fluoro-n-propoxycarbonyl, 1-chlorocyclopropoxycarbonyl, 2-bromocyclopropoxycarbonyl, 3,3,4,4,4-pentafluoro-2-butoxycarbonyl, nonafluoro-n-butoxycarbonyl, nonafluoro-2-butoxycarbonyl, 5,5,5-trifluoro-n-pentyloxycarbonyl, 4,4,5,5,5-pentafluoro-2-pentyloxycarbonyl, 3-chloro-n-pentyloxycarbonyl, 4-bromo-2-pentyloxycarbonyl, 4-chlorobutyloxycarbonyl, 2-iodo-n-propyloxycarbonyl, and the like.


The “C2-C7 alkylcarbonylamino group” represents, for example, a linear, branched, or cyclic alkylcarbonylamino group having from 2 to 7 carbon atoms, such as acetylamino, propionylamino, n-propylcarbonylamino, i-propylcarbonylamino, cyclopropylcarbonylamino, n-butylcarbonylamino, s-butylcarbonylamino, i-butylcarbonylamino, t-butylcarbonylamino, n-pentylcarbonylamino, i-pentylcarbonylamino, n-hexylcarbonylamino, cyclohexylcarbonylamino, and the like.


The “C2-C7 haloalkylcarbonylamino group” represents, for example, a linear, branched, or cyclic alkylcarbonylamino group having from 2 to 7 carbon atoms, that is substituted with one or more halogen atoms which may be the same as or different from each other, such as trifluoroacetylamino, pentafluoropropionylamino, 2-chloropropionylamino, 2,2,2-trifluoropropionylamino, heptafluoro-n-propylcarbonylamino, heptafluoro-i-propylcarbonylamino, 1,1,1,3,3,3-hexafluoro-2-propylcarbonylamino, 3-fluoro-n-propylcarbonylamino, 1-chlorocyclopropylcarbonylamino, 2-bromocyclopropylcarbonylamino, 3,3,4,4,4-pentafluoro-2-butylcarbonylamino, nonafluoro-n-butylcarbonylamino, nonafluoro-2-butylcarbonylamino, 5,5,5-trifluoro-n-pentylcarbonylamino, 4,4,5,5,5-pentafluoro-2-pentylcarbonylamino, 3-chloro-n-pentylcarbonylamino, 4-bromo-2-pentylcarbonylamino, 4-chlorobutylcarbonylamino, 2-iodo-n-propylcarbonylamino, and the like.


The “C2-C7 alkoxycarbonylamino group” represents, for example, a linear, branched, or cyclic alkoxycarbonylamino group having from 2 to 7 carbon atoms, such as methoxycarbonylamino, ethoxycarbonylamino, n-propyloxycarbonylamino, i-propyloxycarbonylamino, cyclopropoxycarbonylamino, n-butoxycarbonylamino, s-butoxycarbonylamino, i-butoxycarbonylamino, t-butoxycarbonylamino, n-pentyloxycarbonylamino, i-pentyloxycarbonylamino, n-hexyloxycarbonylamino, cyclohexyloxycarbonylamino, and the like.


The “C2-C7 haloalkoxycarbonylamino group” represents, for example, a linear, branched, or cyclic alkoxycarbonylamino group having from 2 to 7 carbon atoms, that is substituted with one or more halogen atoms which may be the same as or different from each other, such as trifluoromethoxycarbonylamino, pentafluoroethoxycarbonylamino, 2-chloroethoxycarbonylamino, 2,2,2-trifluoroethoxycarbonylamino, heptafluoro-n-propoxycarbonylamino, heptafluoro-i-propoxycarbonylamino, 1,1,1,3,3,3-hexafluoro-2-propoxycarbonylamino, 3-fluoro-n-propoxycarbonylamino, 1-chlorocyclopropoxycarbonylamino, 2-bromocyclopropoxycarbonylamino, 3,3,4,4,4-pentafluoro-2-butoxycarbonylamino, nonafluoro-n-butoxycarbonylamino, nonafluoro-2-butoxycarbonylamino, 5,5,5-trifluoro-n-pentyloxycarbonylamino, 4,4,5,5,5-pentafluoro-2-pentyloxycarbonylamino, 3-chloro-n-pentyloxycarbonylamino, 4-bromo-2-pentyloxycarbonylamino, 4-chlorobutyloxycarbonylamino, 2-iodo-n-propyloxycarbonylamino, and the like.


The “C2-C7 alkoxycarbonyloxy group” represents, for example, a linear, branched, or cyclic alkoxycarbonyloxy group having from 2 to 7 carbon atoms, such as methoxycarbonyloxy, ethoxycarbonyloxy, n-propyloxycarbonyloxy, i-propyloxycarbonyloxy, cyclopropoxycarbonyloxy, n-butoxycarbonyloxy, s-butoxycarbonyloxy, i-butoxycarbonyloxy, t-butoxycarbonyloxy, n-pentyloxycarbonyloxy, i-pentyloxycarbonyloxy, n-hexyloxycarbonyloxy, cyclohexyloxycarbonyloxy, and the like.


The “C2-C7 haloalkoxycarbonyloxy group” represents, for example, a linear, branched, or cyclic alkoxycarbonyloxy group having from 2 to 7 carbon atoms, that is substituted with one or more halogen atoms which may be the same as or different from each other, such as trifluoromethoxycarbonyloxy, pentafluoroethoxycarbonyloxy, 2-chloroethoxycarbonyloxy, 2,2,2-trifluoroethoxycarbonyloxy, heptafluoro-n-propoxycarbonyloxy, heptafluoro-i-propoxycarbonyloxy, 1,1,1,3,3,3-hexafluoro-2-propoxycarbonyloxy, 3-fluoro-n-propoxycarbonyloxy, 1-chlorocyclopropoxycarbonyloxy, 2-bromocyclopropoxycarbonyloxy, 3,3,4,4,4-pentafluoro-2-butoxycarbonyloxy, nonafluoro-n-butoxycarbonyloxy, nonafluoro-2-butoxycarbonyloxy, 5,5,5-trifluoro-n-pentyloxycarbonyloxy, 4,4,5,5,5-pentafluoro-2-pentyloxycarbonyloxy, 3-chloro-n-pentyloxycarbonyloxy, 4-bromo-2-pentyloxycarbonyloxy, 4-chlorobutyloxycarbonyloxy, 2-iodo-n-propyloxycarbonyloxy, and the like.


The “C1-C6 alkylamino group” represents, for example, a linear, branched, or cyclic alkylamino group having from 1 to 6 carbon atoms, such as methylamino, dimethylamino, ethylamino, diethylamino, n-propylamino, i-propylamino, cyclopropylamino, n-butylamino, s-butylamino, i-butylamino, t-butylamino, n-pentylamino, i-pentylamino, n-hexylamino, cyclohexylamino, and the like.


The “C1-C6 haloalkylamino group” represents, for example, a linear, branched, or cyclic alkylamino group having from 1 to 6 carbon atoms substituted with one or more halogen atoms which may be the same as or different from each other, such as trifluoromethylamino, ditrifluoromethylamino, pentafluoroethylamino, dipentafluoroethylamino, 2-chloroethylamino, 2,2,2-trifluoroethylamino, heptafluoro-n-propylamino, heptafluoro-i-propylamino, 1,1,1,3,3,3-hexafluoro-2-propylamino, 3-fluoro-n-propylamino, 1-chlorocyclopropylamino, 2-bromocyclopropylamino, 3,3,4,4,4-pentafluoro-2-butylamino, nonafluoro-n-butylamino, nonafluoro-2-butylamino, 5,5,5-trifluoro-n-pentylamino, 4,4,5,5,5-pentafluoro-2-pentylamino, 3-chloro-n-pentylamino, 4-bromo-2-pentylamino, 4-chlorobutylamino, 2-iodo-n-propylamino, and the like.


The “C2-C6 alkenyloxy group” represents, for example, an alkenyloxy group having from 2 to 6 carbon atoms, that has a double bond in the carbon chain, such as vinyloxy, allyloxy, 2-butenyloxy, 3-butenyloxy, and the like.


The “C2-C6 haloalkenyloxy group” represents, for example, a linear or branched alkenyloxy group having from 2 to 6 carbon atoms, that is substituted with one or more halogen atoms which may be the same as or different from each other and has a double bond in the carbon chain, such as 3,3-difluoro-2-propenyloxy, 3,3-dichloro-2-propenyloxy, 3,3-dibromo-2-propenyloxy, 2,3-dibromo-2-propenyloxy, 4,4-difluoro-3-butenyloxy, 3,4,4-tribromo-3-butenyloxy, and the like.


The “C2-C6 alkynyloxy group” represents, for example, an alkynyloxy group having from 2 to 6 carbon atoms, that has a triple bond in the carbon chain, such as propargyloxy, 1-butyn-3-yloxy, 1-butyn-3-methyl-3-yloxy, and the like.


The “C2-C6 haloalkynyloxy group” represents, for example, a linear or branched alkynyloxy group having from 2 to 6 carbon atoms, that is substituted with one or more halogen atoms which may be the same as or different from each other and has a triple bond in the carbon chain, such as fluoroethynyloxy, chloroethynyloxy, bromoethynyloxy, 3,3,3-trifluoro-1-propynyloxy, 3,3,3-trichloro-1-propynyloxy, 3,3,3-tribromo-1-propynyloxy, 4,4,4-trifluoro-1-butynyloxy, 4,4,4-trichloro-1-butynyloxy, 4,4,4-tribromo-1-butynyloxy, and the like.


The “C3-C9 cycloalkoxy group” represents, for example, a cycloalkyloxy group having from 3 to 9 carbon atoms, that has a cyclic structure, such as cyclopropyloxy, cyclobutyloxy, cyclopentyloxy, 2-methylcyclopentyloxy, 3-methylcyclopentyloxy, cyclohexyloxy, 2-methylcyclohexyloxy, 3-methylcyclohexyloxy, 4-methylcyclohexyloxy, and the like.


The “C3-C9 halocycloalkoxy group” represents, for example, a cycloalkyloxy group having from 3 to 9 carbon atoms, that is substituted with one or more halogen atoms which may be the same as or different from each other and has a cyclic structure, such as 2,2,3,3-tetrafluorocyclobutyloxy, 2-chlorocyclohexyloxy, 4-chlorocyclohexyloxy, and the like.


The “C3-C7 alkenylcarbonyl group” represents, for example, an alkenylcarbonyl group having from 3 to 7 carbon atoms, that has a double bond in the carbon chain, such as vinylcarbonyl, allylcarbonyl, 2-butenylcarbonyl, 3-butenylcarbonyl, and the like.


The “C3-C7 haloalkenylcarbonyl group” represents an alkenylcarbonyl group having from 3 to 7 carbon atoms, that is substituted with one or more halogen atoms which may be the same as or different from each other and has a double bond in the carbon chain, such as 3,3-difluoro-2-propenylcarbonyl, 3,3-dichloro-2-propenylcarbonyl, 3,3-dibromo-2-propenylcarbonyl, 2,3-dibromo-2-propenylcarbonyl, 4,4-difluoro-3-butenylcarbonyl, 3,4,4-tribromo-3-butenylcarbonyl, and the like.


The “C3-C7 alkynylcarbonyl group” represents an alkynylcarbonyl group having from 3 to 7 carbon atoms and has a triple bond in the carbon chain, such as propargylcarbonyl, 1-butyn-3-ylcarbonyl, 1-butyn-3-methyl-3-ylcarbonyl, and the like.


The “C3-C7 haloalkynylcarbonyl group” represents, for example, a linear or branched alkynylcarbonyl group having from 3 to 7 carbon atoms, that is substituted with one or more halogen atoms which may be the same as or different from each other and has a triple bond in the carbon chain, such as fluoroethynylcarbonyl, chloroethynylcarbonyl, bromoethynylcarbonyl, 3,3,3-trifluoro-1-propynylcarbonyl, 3,3,3-trichloro-1-propynylcarbonyl, 3,3,3-tribromo-1-propynylcarbonyl, 4,4,4-trifluoro-1-butynylcarbonyl, 4,4,4-trichloro-1-butynylcarbonyl, 4,4,4-tribromo-1-butynylcarbonyl, and the like.


The “C4-C10 cycloalkylcarbonyl group” represents, for example, a cycloalkylcarbonyl group having from 4 to 10 carbon atoms, that has a cyclic structure, such as cyclopropylcarbonyl, cyclobutylcarbonyl, cyclopentylcarbonyl, 2-methylcyclopentylcarbonyl, 3-methylcyclopentylcarbonyl, cyclohexylcarbonyl, 2-methylcyclohexylcarbonyl, 3-methylcyclohexylcarbonyl, 4-methylcyclohexylcarbonyl, and the like.


The “C4-C10 halocycloalkylcarbonyl group” represents, for example, a cycloalkylcarbonyl group having from 4 to 10 carbon atoms, that is substituted with one or more halogen atoms which may be the same as or different from each other and has a cyclic structure, such as 2,2,3,3-tetrafluorocyclobutylcarbonyl, 2-chlorocyclohexylcarbonyl, 4-chlorocyclohexylcarbonyl, and the like.


The “C3-C7 alkenyloxycarbonyl group” represents an alkenyloxycarbonyl group having 3 to 7 carbon atoms, that has a double bond in the carbon chain, such as vinyloxycarbonyl, allyloxycarbonyl, 2-butenyloxycarbonyl, 3-butenyloxycarbonyl, and the like.


The “C3-C7 haloalkenyloxycarbonyl group” represents, for example, a linear or branched alkenyloxycarbonyl group having from 3 to 7 carbon atoms, that is substituted with one or more halogen atoms which may be the same as or different from each other and has a double bond in the carbon chain, such as 3,3-difluoro-2-propenyloxycarbonyl, 3,3-dichloro-2-propenyloxycarbonyl, 3,3-dibromo-2-propenyloxycarbonyl, 2,3-dibromo-2-propenyloxycarbonyl, 4,4-difluoro-3-butenyloxycarbonyl, 3,4,4-tribromo-3-butenyloxycarbonyl, and the like.


The “C3-C7 alkynyloxycarbonyl group” represents, for example, an alkynyloxycarbonyl group having from 3 to 7 carbon atoms, that has a triple bond in the carbon chain, such as propargyloxycarbonyl, 1-butyn-3-yloxycarbonyl, 1-butyn-3-methyl-3-yloxycarbonyl, and the like.


The “C3-C7 haloalkynyloxycarbonyl group” represents, for example, a linear or branched alkynyloxycarbonyl group having from 3 to 7 carbon atoms, that is substituted with one or more halogen atoms which may be the same as or different from each other and has a triple bond in the carbon chain, such as fluoroethynyloxycarbonyl, chloroethynyloxycarbonyl, bromoethynyloxycarbonyl, 3,3,3-trifluoro-1-propynyloxycarbonyl, 3,3,3-trichloro-1-propynyloxycarbonyl, 3,3,3-tribromo-1-propynyloxycarbonyl, 4,4,4-trifluoro-1-butynyloxycarbonyl, 4,4,4-trichloro-1-butynyloxycarbonyl, 4,4,4-tribromo-1-butynyloxycarbonyl, and the like.


The “C4-C10 cycloalkyloxycarbonyl group” represents, for example, a cycloalkyloxycarbonyl group having from 4 to 10 carbon atoms, that has a cyclic structure, such as cyclopropyloxycarbonyl, cyclobutyloxycarbonyl, cyclopentyloxycarbonyl, 2-methylcyclopentyloxycarbonyl, 3-methylcyclopentyloxycarbonyl, cyclohexyloxycarbonyl, 2-methylcyclohexyloxycarbonyl, 3-methylcyclohexyloxycarbonyl, 4-methylcyclohexyloxycarbonyl, and the like.


The “C4-C10 halocycloalkyloxycarbonyl group” represents, for example, a cycloalkyloxycarbonyl group having from 4 to 10 carbon atoms, that is substituted with one or more halogen atoms which may be the same as or different from each other and has a cyclic structure, such as 2,2,3,3-tetrafluorocyclobutyloxycarbonyl, 2-chlorocyclohexyloxycarbonyl, 4-chlorocyclohexyloxycarbonyl, and the like.


The “C2-C6 alkenylamino group” represents, for example, an alkenylamino group having 2 to 6 carbon atoms, that has a double bond in the carbon chain, such as vinylamino, allylamino, 2-butenylamino, 3-butenylamino, and the like.


The “C2-C6 haloalkenylamino group” represents a linear or branched alkenylamino group having from 2 to 6 carbon atoms, that is substituted with one or more halogen atoms which may be the same as or different from each other and has a double bond in the carbon chain, such as 3,3-difluoro-2-propenylamino, 3,3-dichloro-2-propenylamino, 3,3-dibromo-2-propenylamino, 2,3-dibromo-2-propenylamino, 4,4-difluoro-3-butenylamino, 3,4,4-tribromo-3-butenylamino, and the like.


The “C2-C6 alkynylamino group” represents, for example, an alkynylamino group having from 2 to 6 carbon atoms, that has a triple bond in the carbon chain, such as propargylamino, 1-butyn-3-ylamino, 1-butyn-3-methyl-3-ylamino, and the like.


The “C2-C6 haloalkynylamino group” represents, for example, a linear or branched alkynylamino group having from 2 to 6 carbon atoms, that is substituted with one or more halogen atoms which may be the same as or different from each other and has a triple bond in the carbon chain, such as fluoroethynylamino, chloroethynylamino, bromoethynylamino, 3,3,3-trifluoro-1-propynylamino, 3,3,3-trichloro-1-propynylamino, 3,3,3-tribromo-1-propynylamino, 4,4,4-trifluoro-1-butynylamino, 4,4,4-trichloro-1-butynylamino, 4,4,4-tribromo-1-butynylamino, and the like.


The “C3-C9 cycloalkylamino group” represents, for example, a cycloalkyl group amino having from 3 to 9 carbon atoms, that has a cyclic structure, such as cyclopropylamino, cyclobutylamino, cyclopentylamino, 2-methylcyclopentylamino, 3-methylcyclopentylamino, cyclohexylamino, 2-methylcyclohexylamino, 3-methylcyclohexylamino, 4-methylcyclohexylamino, and the like.


The “C3-C9 halocycloalkylamino group” represents, for example, a cycloalkylamino group having from 3 to 9 carbon atoms, that is substituted with one or more halogen atoms which may be the same as or different from each other and has a cyclic structure, such as 2,2,3,3-tetrafluorocyclobutylamino, 2-chlorocyclohexylamino, 4-chlorocyclohexylamino, and the like.


The “C2-C7 alkylaminocarbonyl group” represents, for example, a linear or branched alkylaminocarbonyl group having from 2 to 7 carbon atoms, such as methylaminocarbonyl, ethylaminocarbonyl, n-propylaminocarbonyl, i-propylaminocarbonyl, n-butylaminocarbonyl, s-butylaminocarbonyl, t-butylaminocarbonyl, n-pentylaminocarbonyl, 2-pentylaminocarbonyl, neopentylaminocarbonyl, 4-methyl-2-pentylaminocarbonyl, n-hexylaminocarbonyl, 3-methyl-n-pentylaminocarbonyl, and the like.


The “C2-C7 haloalkylaminocarbonyl group” represents, for example, a linear or branched alkylaminocarbonyl group having from 2 to 7 carbon atoms, that is substituted with one or more halogen atoms which may be the same as or different from each other, such as trifluoromethylaminocarbonyl, pentafluoroethylaminocarbonyl, heptafluoro-n-propylaminocarbonyl, heptafluoro-i-propylaminocarbonyl, 2,2-difluoroethylaminocarbonyl, 2,2-dichloroethylaminocarbonyl, 2,2,2-trifluoroethylaminocarbonyl, 2-fluoroethylaminocarbonyl, 2-chloroethylaminocarbonyl, 2-bromoethylaminocarbonyl, 2-iodoethylaminocarbonyl, 2,2,2-trichloroethylaminocarbonyl, 2,2,2-tribromoethylaminocarbonyl, 1,3-difluoro-2-propylaminocarbonyl, 1,3-dichloro-2-propylaminocarbonyl, 1-chloro-3-fluoro-2-propylaminocarbonyl, 1,1,1-trifluoro-2-propylaminocarbonyl, 2,3,3,3-trifluoro-n-propylaminocarbonyl, 4,4,4-trifluoro-n-butylaminocarbonyl, 1,1,1,3,3,3-hexafluoro-2-propylaminocarbonyl, 1,1,1,3,3,3-hexafluoro-2-chloro-2-propylaminocarbonyl, 1,1,1,3,3,3-hexafluoro-2-bromo-2-propylaminocarbonyl, 1,1,2,3,3,3-hexafluoro-2-chloro-n-propylaminocarbonyl, 1,1,2,3,3,3-hexafluoro-2-bromo-n-propylaminocarbonyl, 1,1,2,3,3,3-hexafluoro-1-bromo-2-propylaminocarbonyl, 2,2,3,3,3-pentafluoro-n-propylaminocarbonyl, 3-fluoro-n-propylaminocarbonyl, 3-chloro-n-propylaminocarbonyl, 3-bromo-n-propylaminocarbonyl, 3,3,4,4,4-pentafluoro-2-butylaminocarbonyl, nonafluoro-n-butylaminocarbonyl, nonafluoro-2-butylaminocarbonyl, 5,5,5-trifluoro-n-pentylaminocarbonyl, 4,4,5,5,5-pentafluoro-2-pentylaminocarbonyl, 3-chloro-n-pentylaminocarbonyl, 4-bromo-2-pentylaminocarbonyl, and the like.


The “C3-C7 alkenylaminocarbonyl group” represents, for example, an alkenylaminocarbonyl group having from 3 to 7 carbon atoms, that has a double bond in the carbon chain, such as vinylaminocarbonyl, allylaminocarbonyl, 2-butenylaminocarbonyl, 3-butenylaminocarbonyl, and the like.


The “C3-C7 haloalkenylaminocarbonyl group” represents, for example, a linear or branched alkenylaminocarbonyl group having from 3 to 7 carbon atoms, that is substituted with one or more halogen atoms which may be the same as or different from each other and has a double bond in the carbon chain, such as 3,3-difluoro-2-propenylaminocarbonyl, 3,3-dichloro-2-propenylaminocarbonyl, 3,3-dibromo-2-propenylaminocarbonyl, 2,3-dibromo-2-propenylaminocarbonyl, 4,4-difluoro-3-butenylaminocarbonyl, 3,4,4-tribromo-3-butenylaminocarbonyl, and the like.


The “C3-C7 alkynylaminocarbonyl group” represents, for example, an alkynylaminocarbonyl group having from 3 to 7 carbon atoms, that has a triple bond in the carbon chain, such as propargylaminocarbonyl, 1-butyn-3-ylaminocarbonyl, 1-butyn-3-methyl-3-ylaminocarbonyl, and the like.


The “C3-C7 haloalkynylaminocarbonyl group” represents, for example, a linear or branched alkynylaminocarbonyl group having from 3 to 7 carbon atoms, that is substituted with one or more halogen atoms which may be the same as or different from each other and has a triple bond in the carbon chain, such as fluoroethynylaminocarbonyl, chloroethynylaminocarbonyl, bromoethynylaminocarbonyl, 3,3,3-trifluoro-1-propynylaminocarbonyl, 3,3,3-trichloro-1-propynylaminocarbonyl, 3,3,3-tribromo-1-propynylaminocarbonyl, 4,4,4-trifluoro-1-butynylaminocarbonyl, 4,4,4-trichloro-1-butynylaminocarbonyl, 4,4,4-tribromo-1-butynylaminocarbonyl, and the like.


The “C4-C10 cycloalkylaminocarbonyl group” represents, for example, a cycloalkylaminocarbonyl group having from 4 to 10 carbon atoms, that has a cyclic structure, such as cyclopropylaminocarbonyl, cyclobutylaminocarbonyl, cyclopentylaminocarbonyl, 2-methylcyclopentylaminocarbonyl, 3-methylcyclopentylaminocarbonyl, cyclohexylaminocarbonyl, 2-methylcyclohexylaminocarbonyl, 3-methylcyclohexylaminocarbonyl, 4-methylcyclohexylaminocarbonyl, and the like.


The “C4-C10 halocycloalkylaminocarbonyl group” represents, for example, a cycloalkylaminocarbonyl group having from 4 to 10 carbon atoms that is substituted with one or more halogen atoms which may be the same as or different from each other and has a cyclic structure, such as 2,3,3-tetrafluorocyclobutylaminocarbonyl, 2-chlorocyclohexylaminocarbonyl, 4-chlorocyclohexylaminocarbonyl, and the like.


The “aryl group” represents, for example, a monocyclic and polycyclic aromatic hydrocarbon, such as phenyl group, naphtyl group, and the like.


The “arylcarbonyloxy group” represents, for example, a arylcarbonyloxy group, such as phenylcarbonyloxy group, naphtylcarbonyloxy group, and the like.


The “arylcarbonylamino group” represents, for example, a arylcarbonylamino group, such as phenylcarbonylamino group, naphtylcarbonylamino group, and the like.


The “C1-C6 alkyl group which may have a substituent” in R1 and R2 represents an unsubstituted linear, branched, or cyclic alkyl group having 1 to 6 carbon atoms, or a linear, branched, or cyclic alkyl group having from 1 to 6 carbon atoms, which is substituted only with at least one of a nitro group, a phenyl group which may have a substituent, and an unsaturated heterocyclic group which may have a substituent. Further, when there are two or more substituents, these substituents may be the same as or different from each other.


The “C1-C6 haloalkyl group which may have a substituent” in R1 and R2 represents a linear, branched, or cyclic alkyl group having from 1 to 6 carbon atoms, which is substituted with one or more halogen atoms, or a linear, branched, or cyclic alkyl group having 1 to 6 carbon atoms, which is substituted with at least one of a nitro group, a phenyl group which may have a substituent, and an unsaturated heterocyclic group which may have a substituent, in addition to one or more halogen atoms.


The “C2-C6 alkenyl group which may have a substituent” in R1 and R2 represents an unsubstituted linear, branched, or cyclic alkenyl group having from 2 to 6 carbon atoms, or a linear, branched, or cyclic alkenyl group having 2 to 6 carbon atoms, which is substituted with at least one of a nitro group, a phenyl group which may have a substituent, and an unsaturated heterocyclic group which may have a substituent. Further, when there are two or more substituents, these substituents may be the same as or different from each other.


The “C2-C6 haloalkenyl group which may have a substituent” in R1 and R2 represents a linear, branched, or cyclic alkenyl group having from 2 to 6 carbon atoms, which is substituted only with one or more halogen atoms, or a linear, branched, or cyclic alkenyl group having 2 to 6 carbon atoms, which is substituted with at least one of a nitro group, a phenyl group which may have a substituent, and an unsaturated heterocyclic group which may have a substituent, in addition to one or more halogen atoms.


The “C2-C6 alkynyl group which may have a substituent” in R1 and R2 represents an unsubstituted linear, branched, or cyclic alkynyl group having from 2 to 6 carbon atoms, or a linear, branched, or cyclic alkynyl group having 2 to 6 carbon atoms, which is substituted with at least one of a nitro group, a phenyl group which may have a substituent, and an unsaturated heterocyclic group which may have a substituent. Further, when there are two or more substituents, these substituents may be the same as or different from each other.


The “C2-C6 haloalkynyl group which may have a substituent” in R1 and R2 represents a linear, branched, or cyclic alkynyl group having from 2 to 6 carbon atoms, which is substituted only with one or more halogen atoms, or a linear, branched, or cyclic alkynyl group having 2 to 6 carbon atoms, which is substituted with at least one of a nitro group, a phenyl group which may have a substituent, and an unsaturated heterocyclic group which may have a substituent, in addition to one or more halogen atoms.


Further, each of the substituents in the present invention may further have a substituent, and examples of the substituent include the following:


one or more substituents selected from a group consisting of a halogen atom, a C1-C6 alkyl group, a C1-C6 haloalkyl group, a C3-C9 cycloalkyl group, a C3-C9 halocycloalkyl group, a C2-C6 alkenyl group, a C2-C6 haloalkenyl group, a C2-C6 alkynyl group, a C2-C6 haloalkynyl group, a C1-C6 alkoxy group, a C1-C6 haloalkoxy group, a C1-C6 alkylthio group, a C1-C6 haloalkylthio group, a C1-C6 alkylsulfinyl group, a C1-C6 haloalkylsulfinyl group, a C1-C6 alkylsulfonyl group, a C1-C6 haloalkylsulfonyl group, a C2-C7 alkylcarbonyl group, a C2-C7 haloalkylcarbonyl group, a C2-C7 alkylcarbonyloxy group, a C2-C7 haloalkylcarbonyloxy group, a C1-C6 alkylsulfonyloxy group, a C1-C6 haloalkylsulfonyloxy group, a C2-C7 alkoxycarbonyl group, a C2-C7 haloalkoxycarbonyl group, a C2-C7 alkylcarbonylamino group, a C2-C7 haloalkylcarbonylamino group, a C2-C7 alkoxycarbonylamino group, a C2-C7 haloalkoxycarbonylamino group, a C2-C7 alkylaminocarbonyl group, a C2-C7 haloalkylaminocarbonyl group, a C1-C6 alkylamino group, a C1-C6 haloalkylamino group, a C2-C6 alkenylamino group, a C2-C6 haloalkenylamino group, a C2-C6 alkynylamino group, a C2-C6 haloalkynylamino group, a C3-C9 cycloalkylamino group, a C3-C9 halocycloalkylamino group, a C3-C7 alkenylaminocarbonyl group, a C3-C7 haloalkenylaminocarbonyl group, a C3-C7 alkynylaminocarbonyl group, a C3-C7 haloalkynylaminocarbonyl group, a C4-C10 cycloalkylaminocarbonyl group, a C4-C10 halocycloalkylaminocarbonyl group, an amino group, a carbamoyl group, a sulfamoyl group, a cyano group, a nitro group, a hydroxyl group, a carboxylic group, a pentafluorosulfanyl group, a phenyl group which may have a substituent, a heterocyclic group which may have a substituent, a benzyl group which may have a substituent, a phenylcarbonyl group which may have a substituent, and a phenylamino group which may have a substituent, and when there are two or more substituents, each substituent may be the same as or different from each other.


The compounds represented by Formula (1), Formula (7), Formula (8), and the like of the present invention may include one or plural chiral carbon atoms or chiral centers in their structural Formulae, and thus two or more optical isomers may exist. However, the present invention includes each of the optical isomers and a mixture thereof at any proportions. Further, the compounds represented by Formula (1), Formula (7), Formula (8), and the like of the present invention may include two or more kinds of geometrical isomers derived from carbon-carbon double bonds in the structural Formulae. However, the present invention includes each of the geometrical isomers and a mixture thereof at any proportions.


The combinations of the substituents or atoms preferred as the substituents or the like for the amide derivative represented by Formula (1) of the present invention are as follows.


T is preferably —C(=G1)-Q1, G1 is preferably an oxygen atom, Q1 is preferably a phenyl group which may have a substituent, or a pyridyl group which may have a substituent, and Q1 is more preferably a phenyl group or a pyridyl group which has one or more substituents selected from a group consisting of a halogen atom, a C1 haloalkyl group, a nitro group, and a cyano group, and when there are two or more substituents, each substituent may be the same as or different from each other.


G3 is preferably an oxygen atom.


R1 is preferably a hydrogen atom or a C1-C3 alkyl group.


R2 is preferably a hydrogen atom.


A is preferably a carbon atom, and K is preferably a non-metal atom group which is combined with A and two carbon atoms to which A bonds to form a benzene ring.


X is preferably a hydrogen atom, a halogen atom, or a cyano group, and more preferably a hydrogen atom, a fluorine atom, or a cyano group.


When X is a substituent other than a hydrogen atom, n is preferably 0, 1, or 2.


Y1 is preferably a halogen atom or a C1-C3 haloalkyl group.


Y5 is preferably a C1-C3 haloalkyl group.


Y2 and Y4 are preferably hydrogen atoms, halogen atoms, or C1-C4 alkyl groups, and more preferably hydrogen atoms.


Y3 is preferably a C2-C5 haloalkyl group, and more preferably a C2-C4 perfluoroalkyl group.


Furthermore, the combinations of the substituent or atom preferred as the substituent and the like for the amide derivative represented by Formula (8) are as follows.


Q1 is preferably a phenyl group or a pyridyl group which has one or more substituents selected from a group consisting of a halogen atom, a C1 haloalkyl group, a nitro group, and a cyano group, and when there are two or more substituents, each substituent may be the same as or different from each other.


R1 is preferably a hydrogen atom or a C1-C3 alkyl group.


R2 is preferably a hydrogen atom.


X1 and X2 are preferably hydrogen atoms or fluorine atoms, and X3 and X4 are preferably hydrogen atoms.


Y1 and Y5 are preferably halogen atoms or C1-C3 haloalkyl groups. Y2 and Y4 are preferably hydrogen atoms. Y3 is preferably a C3-C4 perfluoroalkyl group.


The representative methods for producing the compound of the present invention are shown below, and the method for producing the amide derivative of the present invention is not limited to the preparation methods below.


In Formula shown in the following preparation method, A, K, X, n, R1, R2, T, G3, Y1, Y2, Y3, Y4, and Y5 represent the same definitions as A, K, X, n, R1, R2, T, G3, Y1, Y2, Y3, Y4, and Y5, respectively, in Formula (1). LG represents a functional group having a leaving ability, such as a halogen atom, a hydroxy group, or the like, Hal represents a chlorine atom or a bromine atom, and Xa, Xb, and Xc represent chlorine atoms, bromine atoms, or iodine atoms.


<Preparation Method 1>




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1-(i): Formula (21)+Formula (22)→Formula (23)


Formula (21)+Formula (22)→Formula (28)


A nitro aromatic carboxamide derivative represented by Formula (23) or Formula (28) can be prepared by reacting a nitro aromatic carboxylic acid derivative having a leaving group represented by Formula (21) with an aromatic amine derivative represented by Formula (22) in a suitable solvent or without a solvent. In the present step, a suitable base can be used.


The solvent may be any of those which do not inhibit the present reaction significantly. Examples thereof may include water and aromatic hydrocarbons such as benzene, toluene, xylene, and the like, halogenated hydrocarbons such as dichloromethane, chloroform, carbon tetrachloride, and the like, chained or cyclic ethers such as diethyl ether, dioxane, tetrahydrofuran, 1,2-dimethoxy ethane, and the like, esters such as ethyl acetate, butyl acetate, and the like, alcohols such as methanol, ethanol, and the like, ketones such as acetone, methyl isobutyl ketone, cyclohexanone, and the like, amides such as dimethyl formamide, dimethylacetamide, and the like, nitriles such as acetonitrile and the like, and inert solvents such as 1,3-dimethyl-2-imidazolidinone and the like. These solvents may be used alone or as a mixture of two or more kinds thereof.


Furthermore, examples of the base may include organic bases such as triethylamine, tri-n-butyl amine, pyridine, 4-dimethylamino pyridine, and the like, alkali metal hydroxides such as sodium hydroxide, potassium hydroxide, and the like, carbonates such as sodium hydrogen carbonate, potassium carbonate, and the like, phosphates such as dipotassium monohydrogen phosphate, trisodium phosphate, and the like, alkali metal hydride salts such as sodium hydride and the like, alkali metal alkoxides such as sodium methoxide, sodium ethoxide, and the like, and lithium amides such as lithium diisopropyl amide, and the like.


These bases may be appropriately used in an amount in the range from 0.01-fold molar equivalent to 5-fold molar equivalents with respect to the compound represented by Formula (21).


The reaction temperature may be appropriately selected from −20° to the reflux temperature of the solvent used. Further, the reaction time may be appropriately selected within the range from several minutes to 96 hours.


Among the compounds represented by Formula (21), the aromatic carbonyl halide derivative can be prepared easily by a general method using a halogenating agent from an aromatic carboxylic acid. Examples of the halogenating agent include thionyl chloride, thionyl bromide, phosphorus oxychloride, oxalyl chloride, phosphorus trichloride, and the like.


Meanwhile, it is possible to prepare the compound represented by Formula (23) or Formula (28) from the nitro aromatic carboxylic acid derivative and the compound represented by Formula (22) without using a halogenating agent. Examples of the method may include a method described in, for example, Chem. Ber. p. 788 (1970), in which a condensing agent such as N,N′-dicyclohexylcarbodiimide and the like is appropriately used, suitably with the use of an additive such as 1-hydroxybenzotriazole and the like. Other condensing agents that can be used in this case may include 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide, 1,1′-carbonylbis-1H-imidazole, and the like.


Furthermore, examples of other methods for producing the compound represented by Formula (23) or Formula (28) may include a mixed anhydride method using chloroformic acid esters, and examples thereof include a method described in J. Am. Chem. Soc., p. 5012 (1967), whereby the compound represented by Formula (23) or Formula (28) can be prepared. Examples of the chloroformic acid esters used in this case may include isobutyl chloroformate, isopropyl chloroformate and the like. In addition to chloroformic acid esters, diethylacetyl chloride, trimethylacetyl chloride and the like may also be included.


Both the method using a condensing agent and the mixed anhydride method are not limited by the solvent, the reaction temperature, and the reaction time according to the literature above. An inert solvent may be used which does not inhibit the progress of the appropriate reaction significantly, and the reaction temperature and the reaction time may also be selected appropriately according to the progress of the reaction.


1-(ii): Formula (23)→Formula (24)


Formula (28)→Formula (29)


An aromatic carboxamide derivative having an amino group represented by Formula (24) or Formula (29) can be derived from the aromatic carboxamide derivative having a nitro group represented by Formula (23) or Formula (28) by means of a reduction reaction. Examples of such reduction include a method using a hydrogenation reaction and a method using a metal compound (for example, stannous chloride (anhydride), iron powder, zinc powder, and the like).


The reaction of the former method can be carried out in a suitable solvent in the presence of a catalyst at normal pressure or a higher pressure under a hydrogen atmosphere. Examples of the catalyst may include palladium catalysts such as palladium-carbon and the like, nickel catalysts such as Raney-nickel and the like, cobalt catalysts, ruthenium catalysts, rhodium catalysts, platinum catalysts, and the like, and examples of the solvent may include water, alcohols such as methanol, ethanol, and the like; aromatic hydrocarbons such as benzene, toluene, and the like; chained or cyclic ethers such as ether, dioxane, tetrahydrofuran, and the like; and esters such as ethyl acetate and the like. The pressure may be appropriately selected within a range of 0.1 MPa to 10 MPa, the reaction temperature may be appropriately selected within a range of −20° C. to the reflux temperature of the solvent used, and the reaction time may be appropriately selected within a range of several minutes to 96 hours, whereby the compound of Formula (24) or Formula (29) can be efficiently prepared.


Examples of the latter method include a method using stannous chloride (anhydride) as a metal compound under the conditions described in “Organic Syntheses” Coll. Vol. III, P. 453.


1-(iii): Formula (24)+Formula (26)→Formula (25)


An aromatic carboxamide or carbamate derivative represented by Formula (25) can be prepared by reacting the aromatic amine derivative represented by Formula (24) with the carboxylic acid derivative or the carbonate ester derivative having a leaving group represented by Formula (26) in a suitable solvent. In the present step, a suitable base or solvent can be used, and as the base or solvent, those exemplified in 1-(i) can be used. Examples of the reaction temperature, the reaction time, and the like may include those exemplified in 1-(i).


In Formula (26), the carbonyl chloride derivative can be prepared easily from a carboxylic acid derivative by a general method using a halogenating agent. The halogenating agent may include those exemplified in 1-(i).


There may be a method for producing a compound represented by Formula (25) from the carboxylic acid derivative (26) and the compound represented by Formula (24) without the use of a halogenating agent, and the preparation can be conducted according to the method exemplified in 1-(i).


1-(iv): Formula (25)+Formula (27)→Formula (1)


The compound represented by Formula (1) of the present invention can be prepared by reacting the amide compound represented by Formula (25) with the compound having a leaving group such as halogen and the like, represented by Formula (27) in a solvent or without a solvent. In the present step, a suitable base or solvent can be used, and as the base or solvent, those exemplified in 1-(i) can be used. Examples of the reaction temperature, the reaction time, and the like may include those exemplified in 1-(i).


1-(v): Formula (28)+Formula (30)→Formula (23)


A compound represented by Formula (23) can be prepared by reacting the amide compound represented by Formula (28) with the compound having a leaving group such as halogen and the like, represented by Formula (30) in a solvent or without a solvent. In the present step, a suitable base or solvent can be used, and as the base or solvent, those exemplified in 1-(i) can be used. Examples of the reaction temperature, the reaction time, and the like may include those exemplified in 1-(i).


1-(vi): Formula (29)→Formula (31)


(Method A)


A compound represented by Formula (31) can be prepared by reacting the compound represented by Formula (29) with an aldehyde or a ketone in a solvent, and reacting them under a hydrogen atmosphere with the addition of a catalyst.


The solvent may be any of those which do not inhibit the progress of the reaction significantly, and examples thereof may include aliphatic hydrocarbons such as hexane, cyclohexane, methylcyclohexane, and the like, aromatic hydrocarbons such as benzene, xylene, toluene, and the like, halogenated hydrocarbons such as dichloromethane, chloroform, carbon tetrachloride, 1,2-dichloroethane, and the like, ethers such as diethyl ether, dioxane, tetrahydrofuran, 1,2-dimethoxy ethane, and the like, amides such as dimethyl formamide, dimethylacetamide, and the like, nitriles such as acetonitrile, propionitrile, and the like, ketones such as acetone, methyl isobutyl ketone, cyclohexanone, methyl ethyl ketone, and the like, esters such as ethyl acetate, butyl acetate, and the like, alcohols such as 1,3-dimethyl-2-imidazolidinone, sulfolane, dimethylsulfoxide, methanol, ethanol, and the like, and water. These solvents may be used alone or as a mixture of two or more kinds thereof.


Examples of the catalyst may include palladium catalysts such as palladium-carbon, palladium hydroxide-carbon, and the like, nickel catalysts such as Raney-nickel and the like, cobalt catalysts, platinum catalysts, ruthenium catalysts, rhodium catalysts, and the like. Examples of the aldehydes may include formaldehyde, acetaldehyde, propionaldehyde, trifluoroacetaldehyde, difluoroacetaldehyde, fluoroacetaldehyde, chloroacetaldehyde, dichloroacetaldehyde, trichloroacetaldehyde, bromoacetaldehyde, and the like.


Examples of the ketones may include acetone, perfluoroacetone, methyl ethyl ketone, and the like.


The reaction pressure may be appropriately selected within the range of 1 atm to 100 atm. The reaction temperature may be appropriately selected within the range from −20° C. to the reflux temperature of the solvent used. Further, the reaction time may be appropriately selected within the range from several minutes to 96 hours.


(Method B)


A compound represented by Formula (31) can be prepared by reacting the compound represented by Formula (29) with an aldehyde or a ketone in a solvent, and treating the product with a reducing agent.


The solvent may be any of those which do not inhibit the progress of the reaction significantly, and examples thereof may include aliphatic hydrocarbons such as hexane, cyclohexane, methylcyclohexane, and the like, aromatic hydrocarbons such as benzene, xylene, toluene, and the like, halogenated hydrocarbons such as dichloromethane, chloroform, carbon tetrachloride, 1,2-dichloroethane, and the like, ethers such as diethyl ether, dioxane, tetrahydrofuran, 1,2-dimethoxy ethane, and the like, amides such as dimethyl formamide, dimethylacetamide, and the like, nitriles such as acetonitrile, propionitrile, and the like, ketones such as acetone, methyl isobutyl ketone, cyclohexanone, methyl ethyl ketone, and the like, esters such as ethyl acetate, butyl acetate, and the like, alcohols such as 1,3-dimethyl-2-imidazolidinone, sulfolane, dimethylsulfoxide, methanol, ethanol, and the like, water, and the like. These solvents may be used alone or as a mixture of two or more kinds thereof.


Examples of the reducing agent may include, for example, borohydrides such as sodium borohydride, sodium cyanoborohydride, sodium triacetate borohydride, and the like.


Examples of the aldehydes may include formaldehyde, acetaldehyde, propionaldehyde, trifluoroacetaldehyde, difluoroacetaldehyde, fluoroacetaldehyde, chloroacetaldehyde, dichloroacetaldehyde, trichloroacetaldehyde, bromoacetaldehyde, and the like.


Examples of the ketones may include acetone, perfluoroacetone, methyl ethyl ketone, and the like.


The reaction temperature may be appropriately selected within the range from −20° C. to the reflux temperature of the solvent used. Further, the reaction time may be appropriately selected within the range from several minutes to 96 hours.


(Method C)


A compound of Formula (31) can be prepared by reacting the compound represented by Formula (29) with an aldehyde in a solvent or without a solvent.


The solvent may be any of those which do not inhibit the progress of the reaction significantly, and examples thereof may include aliphatic hydrocarbons such as hexane, cyclohexane, methylcyclohexane, and the like, aromatic hydrocarbons such as benzene, xylene, toluene, and the like, halogenated hydrocarbons such as dichloromethane, chloroform, carbon tetrachloride, 1,2-dichloroethane, and the like, ethers such as diethyl ether, dioxane, tetrahydrofuran, 1,2-dimethoxy ethane, and the like, amides such as dimethyl formamide, dimethylacetamide, and the like, nitriles such as acetonitrile, propionitrile, and the like, ketones such as acetone, methyl isobutyl ketone, cyclohexanone, methyl ethyl ketone, and the like, esters such as ethyl acetate, butyl acetate, and the like, alcohols such as 1,3-dimethyl-2-imidazolidinone, sulfolane, dimethylsulfoxide, methanol, ethanol, and the like, inorganic acids such as sulfuric acid, hydrochloric acid, and the like, organic acids such as formic acid, acetic acid, and the like, water, and the like. These solvents may be used alone or as a mixture of two or more kinds thereof.


Examples of the aldehydes may include formaldehyde, acetaldehyde, propionaldehyde, and the like.


The reaction temperature may be appropriately selected within the range from −20° C. to the reflux temperature of the solvent used, and the reaction time may be appropriately selected within the range from several minutes to 96 hours.


1-(vii): Formula (31)+Formula (26)→General Formula (32)


An aromatic carboxamide or carbamate derivative represented by Formula (32) can be prepared by reacting the aromatic amine derivative represented by Formula (31) with the carboxylic acid derivative or the carbonate ester derivative having a leaving group represented by Formula (26) in a suitable solvent. In the present step, a suitable base or solvent can be used, and as the base or solvent, those exemplified in 1-(i) can be used. Examples of the reaction temperature, the reaction time, and the like may include those exemplified in 1-(i).


In Formula (26), the carbonyl chloride derivative can be prepared easily from a carboxylic acid derivative by a general method using a halogenating agent. The halogenating agent may include those exemplified in 1-(i).


There may be exemplified a method for producing a compound represented by Formula (32) from the carboxylic acid derivative (26) and the compound represented by Formula (31) without the use of a halogenating agent, and the preparation can be conducted according to the method exemplified in 1-(i).


1-(viii): Formula (32)+Formula (30)→Formula (1)


The compound represented by Formula (1) of the present invention can be prepared by reacting the amide compound represented by Formula (32) with the compound having a leaving group such as a halogen and the like, represented by Formula (30) in a solvent or without a solvent. In the present step, a suitable base or solvent can be used, and as the base or solvent, those exemplified in 1-(i) can be used. Examples of the reaction temperature, the reaction time, and the like may include those exemplified in 1-(i).


<Preparation Method 2>




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2-(i): Formula (33)+Formula (22)→Formula (34)


A compound represented by Formula (34) can be prepared by reacting the compound represented by Formula (33) with a compound represented by Formula (22) under the condition described in l-(i).


2-(ii): Formula (34)→Formula (36)


A compound represented by Formula (36) can be prepared by carrying out an amination reaction using an amination agent such as ammonia and the like according to the conditions described, for example, in J. Org. Chem. p. 280 (1958). However, the conditions such as a reaction solvent and the like are not restricted to those described in the literature, and an inert solvent which does not inhibit the proper progress of the reaction significantly may be used. The reaction temperature and reaction time may be suitably selected as the reaction proceeds. Further, examples of the amination agent include methylamine, ethylamine or the like, in addition to ammonia.


2-(iii): Formula (36)+Formula (26)→Formula (1)


The compound represented by Formula (1) can be prepared by reacting the compound represented by Formula (36) with a compound represented by Formula (26) according to the conditions described in 1-(i).


<Preparation Method 3>




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3-(i): Formula (29)+Formula (26)→Formula (35)


An aromatic carboxamide or carbamate derivative represented by Formula (35) can be prepared by reacting the aromatic amine derivative represented by Formula (29) with the carboxylic acid derivative or the carbonate ester derivative having a leaving group represented by Formula (26) in a suitable solvent. In the present step, a suitable base or solvent can be used, and as the base or solvent, those exemplified in 1-(i) can be used. Examples of the reaction temperature, the reaction time, and the like may include those exemplified in 1-(i).


In Formula (26), the carbonyl chloride derivative can be prepared easily from a carboxylic acid derivative by a general method using a halogenating agent. The halogenating agent may include those exemplified in 1-(i).


There may be exemplified a method for producing a compound represented by Formula (35) from the carboxylic acid derivative (26) and the compound represented by Formula (29) without the use of a halogenating agent, and the preparation can be conducted according to the method exemplified in 1-(i).


3-(ii): Formula (35)+Formula (27)→Formula (1a)


The compound represented by Formula (1a) of the present invention can be prepared by reacting the amide compound represented by Formula (35) with the compound having a leaving group such as halogen and the like, represented by Formula (27) in a solvent or without a solvent. In the present step, a suitable base or solvent can be used, and as the base or solvent, those exemplified in 1-(i) can be used. Examples of the reaction temperature, the reaction time, and the like may include those exemplified in 1-(i).


<Preparation Method 4>




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4-(i): Formula (24)→Formula (36)


A compound represented by Formula (36) can be prepared by reacting the compound represented by Formula (24) as a starting material according to the conditions of (Method A), (Method B), or (Method C) described in 1-(vi).


4-(i′): Formula (24)+Formula (27)→Formula (36)


An aromatic carboxamide represented by Formula (36) can be prepared by reacting the aromatic amine derivative represented by Formula (24) with the carboxylic acid derivative or the carbonate ester derivative having a leaving group represented by Formula (27) in a suitable solvent. In the present step, a suitable base or solvent can be used, and as the base or solvent, those exemplified in 1-(i) can be used. Examples of the reaction temperature, the reaction time, and the like may include those exemplified in 1-(i).


In Formula (27), the carbonyl chloride derivative can be prepared easily from a carboxylic acid derivative by a general method using a halogenating agent. The halogenating agent may include those exemplified in 1-(i).


There may be exemplified a method for producing a compound represented by Formula (36) from the carboxylic acid derivative (27) and the compound represented by Formula (24) without the use of a halogenating agent, and the preparation can be conducted according to the method exemplified in 1-(i).


4-(ii): Formula (36)+Formula (26)→Formula (1)


A compound represented by Formula (1) can be prepared by reacting the compound represented by Formula (36) and the compound represented by Formula (26) as starting materials according to the conditions described in 1-(i).


<Preparation Method 5>




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5-(i): Formula (37)+Formula (22)→Formula (38)


A compound represented by Formula (38) can be prepared by reacting the compound represented by Formula (37) and the compound represented by Formula (22) according to the conditions described in 1-(i).


5-(ii): Formula (38)→Formula (39)


A compound represented by Formula (39) can be prepared by reacting the nitro aromatic carboxamide derivative represented by Formula (38) with a suitable fluorinating agent in a suitable solvent or without a solvent.


The solvent may be any of those which do not inhibit the progress of the reaction significantly, and examples thereof may include aliphatic hydrocarbons such as hexane, cyclohexane, methylcyclohexane, and the like, aromatic hydrocarbons such as benzene, toluene, xylene, and the like, halogenated hydrocarbons such as dichloromethane, chloroform, carbon tetrachloride, 1,2-dichloroethane, and the like, chained or cyclic ethers such as diethyl ether, dioxane, tetrahydrofuran, 1,2-dimethoxy ethane, and the like, esters such as ethyl acetate, butyl acetate, and the like, ketones such as acetone, methyl isobutyl ketone, cyclohexanone, methyl ethyl ketone, and the like, nitriles such as acetonitrile, propionitrile, and the like, and aprotic polar solvents such as 1,3-dimethyl-2-imidazolidinone, sulfolane, dimethylsulfoxide, N,N-dimethyl formamide, N-methyl pyrrolidone, N,N-dimethylacetamide, and the like. These solvents may be used alone or as a mixture of two or more kinds thereof.


Examples of the fluorinating agent may include 1,1,2,2-tetrafluoroethyl diethylamine, 2-chloro-1,1,2-trifluoroethyl diethylamine, trifluorodiphenylphospholane, difluorotriphenylphospholane, fluoroformic acid esters, sulfur tetrafluoride, potassium fluoride, potassium hydrogen fluoride, cesium fluoride, rubidium fluoride, sodium fluoride, lithium fluoride, antimony (III) fluoride, antimony (V) fluoride, zinc fluoride, cobalt fluoride, lead fluoride, copper fluoride, mercury (II) fluoride, silver fluoride, silver fluoroborate, thallium (I) fluoride, molybdenum (VI) fluoride, arsenic (III) fluoride, bromine fluoride, selenium tetrafluoride, tris(dimethylamino)sulfonium difluorotrimethylsilicate, sodium hexafluorosilicate, quaternary ammonium fluorides, (2-chloroethyl) diethylamine, diethylaminosulfur trifluoride, morpholinosulfur trifluoride, silicon tetrafluoride, hydrogen fluoride, hydrofluoric acid, hydrogen fluoride-pyridine complex, hydrogen fluoride-triethylamine complex, hydrogen fluoride salts, bis(2-methoxyethyl)amino sulfurtrifluoride, 2,2-difluoro-1,3-dimethyl-2-imidazolidinone, iodine pentafluoride, tris(diethylamino)phosphonium 2,2,3,3,4,4-hexafluorocyclobutanilide, triethylammonium hexafluorocylcobutanilide, hexafluoropropene, and the like. These fluorinating agents may be used alone or as a mixture of two or more kinds thereof.


The fluorinating agent may be appropriately selected and used as a solvent, in the range of 1-fold molar equivalent to 10-fold molar equivalents with respect to the nitro aromatic carboxamide derivative represented by Formula (38).


Additives may be used, and examples thereof may include crown ethers such as 18-crown-6 and the like, phase transfer catalysts such as a tetraphenylphosphonium salt and the like, inorganic salts such as calcium fluoride, calcium chloride, and the like, metal oxides such as mercury oxide and the like, ion exchange resins, and the like. These additives may not only be added to the reaction system but also used as a pretreating agent for the fluorinating agent.


The reaction temperature may be appropriately selected within the range from −80° C. to the reflux temperature of the solvent used, and the reaction time may be appropriately selected within the range from several minutes to 96 hours.


<Preparation Method 6>




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6-(i): Formula (40)+Formula (22)→Formula (41)


A compound represented by Formula (41) can be prepared by reacting the compound represented by Formula (40) with a compound represented by Formula (22) according to the conditions described in 1-(i).


6-(ii): Formula (41)→Formula (42)


A compound represented by Formula (42) can be prepared by reacting the halogen aromatic carboxamide derivative represented by Formula (41) with a suitable cyanating agent in a suitable solvent or without a solvent.


The solvent may be any of those which do not inhibit the progress of the present reaction significantly. Examples thereof may include aliphatic hydrocarbons such as hexane, cyclohexane, methylcyclohexane, and the like, aromatic hydrocarbons such as benzene, toluene, xylene, and the like, halogenated hydrocarbons such as dichloromethane, chloroform, carbon tetrachloride, 1,2-dichloroethane, and the like, chained or cyclic ethers such as diethyl ether, dioxane, tetrahydrofuran, 1,2-dimethoxy ethane, and the like, esters such as ethyl acetate, butyl acetate, and the like, ketones such as acetone, methyl isobutyl ketone, cyclohexanone, methyl ethyl ketone, and the like, nitriles such as acetonitrile, propionitrile, and the like, and aprotic polar solvents such as 1,3-dimethyl-2-imidazolidinone, sulfolane, dimethylsulfoxide, N,N-dimethyl formamide, N-methyl pyrrolidone, N,N-dimethylacetamide, and the like. These solvents may be used alone or as a mixture of two or more kinds thereof.


Examples of the cyanating agent include cyanide salts such as sodium cyanide, potassium cyanide, sodium cyanoborohydride, and the like, metal cyanides such as copper cyanide, silver cyanide, lithium cyanide, and the like, hydrogen cyanide, tetraehtylammonium cyanide, and the like.


These cyanating agents may be appropriately selected and used in the range of 1-fold molar equivalent to 10-fold molar equivalents with respect to the halogen aromatic carboxamide derivative represented by Formula (41).


Additives may be used, and examples thereof may include crown ethers such as 18-crown-6 and the like, phase transfer catalysts such as a tetraphenylphosphonium salt and the like, inorganic salts such as sodium iodide and the like.


The reaction temperature may be appropriately selected within the range from −20° C. to the reflux temperature of the solvent used. Further, the reaction time may be appropriately selected within the range from several minutes to 96 hours.


<Preparation Method 7>




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7-(i): Formula (43)→Formula (44)


A compound represented by Formula (44) can be prepared by reacting the compound represented by Formula (43) with a Lawesson's reagent according to the known conditions described in Synthesis p. 463 (1993), Synthesis p. 829 (1984) and the like. The conditions such as a solvent, reaction temperature and the like are not restricted to those described in the literature.


2-(ii): Formula (44)+Formula (26)→Formula (45)


A compound represented by Formula (45) can be prepared by reacting the compound represented by Formula (44) with a compound represented by Formula (26) according to the conditions described in 1-(i).


<Preparation Method 8>




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8: Formula (46)→Formula (47)+Formula (48)


The compounds represented by Formula (47) and Formula (48) can be prepared from a compound represented by Formula (46) according to the conditions described in 7-(i). The conditions such as a solvent, a reaction temperature, and the like are not restricted to those described in the literature. These two compounds can be easily separated and purified by a known separation and purification technique such as silica gel column chromatography and the like.


<Preparation Method 9>




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9-(i): Formula (49)+Formula (26)→Formula (50)


Carboxylic acids having an acylamino group represented by Formula (50) can be prepared by reacting a carboxylic acid having an amino group represented by Formula (49) as a starting material with a compound represented by Formula (26) according to the conditions described in 1-(i).


9-(ii): Formula (50)→Formula (51)


A compound represented by Formula (51) can be prepared by a known general method including reacting the compound represented by Formula (50) with thionyl chloride, oxalyl chloride, phosgene, phosphorus oxychloride, phosphorus pentachloride, phosphorus trichloride, thionyl bromide, phosphorus tribromide, diethylaminosulfur trifluoride, or the like.


9-(iii): Formula (51)+Formula (22)→Formula (1)


The compound represented by Formula (1) can be prepared by reacting a compound represented by Formula (51) with a compound represented by Formula (22) according to the conditions described in 1-(i).


9-(iv): Formula (50)+Formula (22)→Formula (1)


The compound represented by Formula (1) can be prepared by reacting the compound represented by Formula (50) with a compound represented by Formula (22) according to the condition using a condensing agent or the condition using a mixed anhydride method according to 1-(i).


In all of the preparation methods as described above, a desired product may be isolated from the reaction system after the reaction is completed according to a general method, but if required, purification can be carried out by operations such as recrystallization, column chromatography, distillation, and the like. In addition, the desired product can be also provided to the subsequent reaction process without being separated from the reaction system.


Hereinbelow, examples of the representative compounds of the amide derivative represented by Formula (1), Formula (7), or Formula (8) as an active ingredient for the pest control agent of the present invention will be given in Table 1 to Table 51 below, but the present invention is not limited thereto.


In addition, in the tables, “n-” represents normal, “i-” represents iso, “s-” represents secondary, “t-” represents tertiary, “Me” represents a methyl group, “Et” represents an ethyl group, “n-Pr” represents a normal propyl group, “i-Pr” represents an isopropyl group, “n-Bu” represents a normal butyl group, “i-Bu” represents an isobutyl group, “s-Bu” represents a secondary butyl group, “t-Bu” represents a tertiary butyl group, “CF3” represents a trifluoromethyl group, “C2F5” represents a pentafluoroethyl group, “n-C3F7” represents a heptafluoronormal propyl group, “i-C3F7” represents a heptafluoroisopropyl group, “OCF3” represents a trifluoromethoxy group, “OC2F5” represents a pentafluoroethoxy group, “H” represents a hydrogen atom, “F” represents a fluorine atom, “Cl” represents a chlorine atom, “Br” represents a bromine atom, “I” represents an iodine atom, “O” represents an oxygen atom, “C(O)” represents a carbonyl group, “CN” represents a cyano group, “Py” represents a pyridyl group, “Ph” represents a phenyl group, and “S(O)2” represents a sulfonyl group, respectively.




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TABLE 1





compound














number
Q1
R1
R2
X1
X2
X3
X4
Y1
Y2
Y3
Y4
Y5







1-1
phenyl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


1-13
4-iodophenyl
H
H
H
CN
H
H
Cl
H
pentafluoroethyl
H
OCF3


1-16
(4-trifluoromethyl) phenyl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
OC2F5


1-17
2-nitrophenyl
H
H
H
CN
H
H
F
H
heptafluoroisopropyl
H
OCF3


1-20
2-cyanophenyl
H
H
H
CN
H
H
Cl
H
pentafluoroethyl
H
OC2F5


1-21
3-cyanophenyl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


1-22
4-cyanophenyl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


1-28
4-bromo-2-chlorophenyl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
OC2F5


1-36
2-fluoropyridin-3-yl
H
H
H
CN
H
H
Cl
H
pentafluoroethyl
H
OCF3


1-37
2-chloropyridin-3-yl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


1-44
6-chloropyridin-3-yl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
OC2F5


1-50
5-fluoropyridin-3-yl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
OC2F5


1-55
5-nitropyridin-3-yl
H
H
H
CN
H
H
Cl
H
pentafluoroethyl
H
OCF3


1-57
4-fluoropyridin-3-yl
H
H
H
CN
H
H
Cl
H
pentafluoroethyl
H
OCF3


1-59
4-bromopyridin-3-yl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
OC2F5


1-60
4-iodopyridin-3-yl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
OC2F5


1-79
phenyl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


1-95
2-nitrophenyl
H
H
H
CN
H
H
F
H
nonafluoro-2-butyl
H
OCF3


1-99
3-cyanophenyl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


1-100
4-cyanophenyl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


1-105
2-chloro-4,5-difluorophenyl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
OC2F5


1-115
2-chloropyridin-3-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


1-121
6-fluoropyridin-3-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
OC2F5


1-130
5-bromopyridin-3-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
OC2F5


1-131
5-iodopyridin-3-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
OC2F5


1-139
4-(trifluoromethyl) pyridin-3-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
OC2F5


1-140
4-nitropyridin-3-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
OC2F5


1-157
phenyl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
OCF3


1-177
3-cyanophenyl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
OCF3


1-178
4-cyanophenyl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
OCF3


1-193
2-chloropyridin-3-yl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
OCF3


1-200
6-chloropyridin-3-yl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
OCF3


1-222
pyridin-4-yl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
OCF3


1-235
phenyl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


1-255
3-cyanophenyl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


1-256
4-cyanophenyl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


1-271
2-chloropyridin-3-yl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


1-313
phenyl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
OCF3


1-314
2-fluorophenyl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
OCF3


1-333
3-cyanophenyl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
OCF3


1-334
4-cyanophenyl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
OCF3


1-349
2-chloropyridin-3-yl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
OCF3


1-356
6-chloropyridin-3-yl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
OCF3


1-391
phenyl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
OCF3


1-411
3-cyanophenyl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
OCF3


1-412
4-cyanophenyl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
OCF3


1-427
2-chloropyridin-3-yl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
OCF3


1-434
6-chloropyridin-3-yl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
OCF3


1-469
phenyl
H
H
H
CN
H
H
F
H
nonafluoro-2-butyl
H
CF3


1-470
phenyl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-471
2-fluorophenyl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-472
3-fluorophenyl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-473
4-fluorophenyl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-474
2-chlorophenyl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-475
3-chlorophenyl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-476
4-chlorophenyl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-477
2-bromophenyl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-478
3-bromophenyl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-479
4-bromophenyl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-480
2-iodophenyl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-481
3-iodophenyl
H
H
H
CN
H
H
Cl
H
pentafluoroethyl
H
CF3


1-482
4-iodophenyl
H
H
H
CN
H
H
Cl
H
pentafluoroethyl
H
CF3


1-483
(2-trifluoromethyl) phenyl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-484
(3-trifluoromethyl) phenyl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-485
(4-trifluoromethyl) phenyl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-486
2-nitrophenyl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-487
3-nitrophenyl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-488
4-nitrophenyl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-489
2-cyanophenyl
H
H
H
CN
H
H
Cl
H
pentafluoroethyl
H
C2F5


1-490
3-cyanophenyl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-491
4-cyanophenyl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-492
2,6-difluorophenyl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-493
3,4-dichlorophenyl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-494
2,4-dichlorophenyl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
C2F5


1-495
2-chloro-4-fluorophenyl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-496
2-chloro-4,5-difluorophenyl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-497
4-bromo-2-chlorophenyl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-498
2-bromo-4-chlorophenyl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


1-499
2-bromo-4-fluorophenyl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-500
2-chloro-4-nitrophenyl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-501
3,5-dicyanophenyl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-502
4-cyano-2-fluorophenyl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-503
2-chloro-4-cyanophenyl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-504
pyrdin-3-yl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-505
2-fuoropyridin-3-yl
H
H
H
CN
H
H
Cl
H
pentafluoroethyl
H
CF3


1-506
2-chloropyridin-3-yl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-507
2-bromopyridin-3-yl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-508
2-iodopyridin-3-yl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-509
2-(trifluoromethyl) pyridin-3-yl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-510
2-nitropyridin-3-yl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-511
2-cyanopyridin-3-yl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-512
6-fluoropyridin-3-yl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-513
6-chloropyridin-3-yl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-514
6-bromopyridin-3-yl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-515
6-iodopyridin-3-yl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-516
6-(trifluoromethyl) pyridin-3-yl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-517
6-nitropyridin-3-yl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-518
6-cyanopyridin-3-yl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-519
5-fluoropyridin-3-yl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
C2F5


1-520
5-chloropyridin-3-yl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-521
5-bromopyridin-3-yl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


1-522
5-iodopyridin-3-yl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
i-C3F7


1-523
5-(trifluoromethyl) pyridin-3-yl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-524
5-nitropyridin-3-yl
H
H
H
CN
H
H
Cl
H
pentafluoroethyl
H
CF3


1-525
5-cyanopyridin-3-yl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-526
4-fluoropyridin-3-yl
H
H
H
CN
H
H
Cl
H
pentafluoroethyl
H
CF3


1-527
4-chloropyridin-3-yl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-528
4-bromopyridin-3-yl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-529
4-iodopyridin-3-yl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-530
4-(trifluoromethyl) pyridin-3-yl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-531
4-nitropyridin-3-yl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-532
4-cyanopyridin-3-yl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-533
2,6-dichloropyridin-3-yl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-534
pyridin-3-yl N-oxide
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-535
pyridin-4-yl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-536
2-chloropyridin-4-yl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-537
3-bromopyridin-4-yl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-538
3,5-dichloropyridin-4-yl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-539
3-(trifluoromethyl) pyridin-4-yl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-540
2,6-dichloropyridin-4-yl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-541
pyridin-4-yl N-oxide
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-542
pyridin-2-yl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-543
3-chloropyridin-2-yl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-544
4-bromopyridin-2-yl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-545
5-iodopyridin-2-yl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-546
6-chloropyridin-2-yl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-547
4-cyanopyridin-2-yl
H
H
H
CN
H
H
Cl
H
pentafluoroethyl
H
CF3


1-548
phenyl
H
H
H
CN
H
H
F
H
nonafluoro-2-butyl
H
CF3


1-549
phenyl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-550
2-fluorophenyl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-551
3-fluorophenyl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-552
4-fluorophenyl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-553
2-chlorophenyl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-554
3-chlorophenyl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-555
4-chlorophenyl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-556
2-bromophenyl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-557
3-bromophenyl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-558
4-bromophenyl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-559
2-iodophenyl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-560
3-iodophenyl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-561
4-iodophenyl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


1-562
(2-trifluoromethyl) phenyl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-563
(3-trifluoromethyl) phenyl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-564
(4-trifluoromethyl) phenyl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-565
2-nitrophenyl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-566
3-nitrophenyl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-567
4-nitrophenyl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-568
2-cyanophenyl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-569
3-cyanophenyl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-570
4-cyanophenyl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-571
2,6-difluorophenyl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-572
3,4-dichlorophenyl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-573
2,4-dichlorophenyl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-574
2-chloro-4-fluorophenyl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-575
2-chloro-4,5-difluorophenyl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-576
4-bromo-2-chlorophenyl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-577
2-bromo-4-chlorophenyl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-578
2-bromo-4-fluorophenyl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


1-579
2-chloro-4-nitrophenyl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-580
3,5-dicyanophenyl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-581
4-cyano-2-fluorophenyl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-582
2-chloro-4-cyanophenyl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-583
pyridin-3-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-584
2-fluoropyridin-3-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-585
2-chloropyridin-3-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-586
2-bromopyridin-3-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-587
2-iodopyridin-3-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-588
2-(trifluoromethyl) pyridin-3-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-589
2-nitropyridin-3-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-590
2-cyanopyridin-3-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-591
6-fluoropyridin-3-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-592
6-chloropyridin-3-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-593
6-bromopyridin-3-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-594
6-iodopyridin-3-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-595
6-(trifluoromethyl) pyridin-3-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-596
6-nitropyridin-3-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-597
6-cyanopyridin-3-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-598
5-fluoropyridin-3-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


1-599
5-chloropyridin-3-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-600
5-bromopyridin-3-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
n-C3F7


1-601
5-iodopyridin-3-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


1-602
5-(trifluoromethyl) pyridin-3-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-603
5-nitropyridin-3-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-604
5-cyanopyridin-3-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-605
4-fluoropyridin-3-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


1-606
4-chloropyridin-3-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-607
4-bromopyridin-3-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-608
4-iodopyridin-3-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-609
4-(trifluoromethyl) pyridin-3-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
n-C3F7


1-610
4-nitropyridin-3-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


1-611
4-cyanopyridin-3-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-612
2,6-dichloropyridin-3-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-613
pyridin-3-yl N-oxide
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-614
pyridin-4-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-615
2-chloropyridin-4-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-616
3-bromopyridin-4-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-617
3,5-dichloropyridin-4-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-618
3-(trifluoromethyl) pyridin-4-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-619
2,6-dicyanopyridin-4-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-620
pyridin-4-yl N-oxide
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-621
pyridin-2-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-622
3-chloropyridin-2-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-623
4-bromopyridin-2-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-624
5-iodopyridin-2-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-625
6-chloropyridin-2-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-626
4-cyanopyridin-2-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


1-627
phenyl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-628
2-fluorophenyl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-629
3-fluorophenyl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-630
4-fluorophenyl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-631
2-chlorophenyl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-632
3-chlorophenyl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-633
4-chlorophenyl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-634
2-bromophenyl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-635
3-bromophenyl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-636
4-bromophenyl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-637
2-iodophenyl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-638
3-iodophenyl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-639
4-iodophenyl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-640
(2-trifluoromethyl) phenyl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-641
(3-trifluoromethyl) phenyl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-642
(4-trifluoromethyl) phenyl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-643
2-nitrophenyl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-644
3-nitrophenyl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-645
4-nitrophenyl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-646
2-cyanophenyl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-647
3-cyanophenyl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-648
4-cyanophenyl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-649
2,6-difluorophenyl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-650
3,4-dichlorophenyl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-651
2,4-dichlorophenyl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-652
2-chloro-4-fluorophenyl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-653
2-chloro-4,5-difluorophenyl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-654
4-bromo-2-chlorophenyl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-655
2-bromo-4-chlorophenyl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-656
2-bromo-2-fluorophenyl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-657
2-chloro-4-nitrophenyl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-658
3,5-dicyanophenyl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-659
4-cyano-2-fluorophenyl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-660
2-chloro-4-cyanophenyl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-661
pyridin-3-yl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-662
2-fluoropyridin-3-yl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-663
2-chloropyridin-3-yl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-664
2-bromopyridin-3-yl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-665
2-iodopyridin-3-yl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-666
2-(trifluoromethyl) pyridin-3-yl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-667
2-nitropyridin-3-yl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-668
2-cyanopyridin-3-yl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-669
6-fluoropyridin-3-yl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-670
6-chloropyridin-3-yl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-671
6-bromopyridin-3-yl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-672
6-iodopyridin-3-yl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-673
6-(trifluoromethyl) pyridin-3-yl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-674
6-nitropyridin-3-yl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-675
6-cyanopyridin-3-yl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-676
5-fluoropyridin-3-yl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-677
5-chloropyridin-3-yl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-678
5-bromopyridin-3-yl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-679
5-iodopyridin-3-yl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-680
5-(trifluoromethyl) pyridin-3-yl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-681
5-nitropyridin-3-yl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-682
5-cyanopyridin-3-yl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-683
4-fluoropyridin-3-yl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-684
4-chloropyridin-3-yl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-685
4-bromopyridin-3-yl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-686
4-iodopyridin-3-yl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-687
4-(trifluoromethyl) pyridin-3-yl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-688
4-nitropyridin-3-yl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-689
4-cyanopyridin-3-yl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-690
2,6-dichloropyridin-3-yl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-691
pyridin-3-yl N-oxide
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-692
pyridin-4-yl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-693
2-chloropyridin-4-yl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-694
3-bromopyridin-4-yl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-695
3,5-dichloropyridin-4-yl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-696
3-(trifluoromethyl) pyridin-4-yl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-697
2,6-dicyanopyridin-4-yl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-698
pyridin-4-yl N-oxide
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-699
pyridin-2-yl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-700
3-chloropyridin-2-yl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-701
4-bromopyridin-2-yl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-702
5-iodopyridin-2-yl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-703
6-chloropyridin-2-yl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-704
4-cyanopyridin-2-yl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-705
phenyl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-706
2-fluorophenyl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-707
3-fluorophenyl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-708
4-fluorophenyl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-709
2-chlorephenyl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-710
3-chlorophenyl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-711
4-chlorophenyl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-712
2-bromophenyl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-713
3-bromophenyl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-714
4-bromophenyl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-715
2-iodophenyl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-716
3-iodophenyl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-717
4-iodophenyl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-718
(2-trifluoromethyl) phenyl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-719
(3-trifluoromethyl) phenyl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-720
(4-trifluoromethyl) phenyl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-721
2-nitrophenyl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-722
3-nitrophenyl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-723
4-nitrophenyl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-724
2-cyanophenyl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-725
3-cyanophenyl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-726
4-cyanophenyl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-727
2,6-diflurophenyl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-728
3,4-dichlorophenyl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-729
2,4-dichlorophenyl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-730
2-chloro-4-flurorophenyl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-731
2-chloro-4,5-diflurorophenyl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-732
4-bromo-2-chlorophenyl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-733
2-bromo-4-chlorophenyl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-734
2-bromo-4-chlorophenyl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-735
2-chloro-4-nitrophenyl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-736
3,5-dicyanophenyl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-737
4-cyano-2-fluorophenyl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-738
2-chloro-4-cyanophenyl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-739
pyridin-3-yl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-740
2-fluoropyridin-3-yl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-741
2-chloropyridin-3-yl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-742
2-bromopyridin-3-yl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-743
2-iodopyridin-3-yl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-744
2-(trifluoromethyl) pyridin-3-yl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-745
2-nitropyridin-3-yl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-746
2-cyanopyridin-3-yl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-747
6-fluoropyridin-3-yl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-748
6-chloropyridin-3-yl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-749
6-bromopyridin-3-yl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-750
6-iodopyridin-3-yl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-751
6-(trifluoromethyl) pyridin-3-yl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-752
6-nitropyridin-3-yl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-753
6-cyanopyridin-3-yl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-754
5-fluoropyridin-3-yl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-755
5-chloropyridin-3-yl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-756
5-bromopyridin-3-yl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-757
5-iodopyridin-3-yl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-758
5-(trifluoromethyl) pyridin-3-yl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-759
5-nitropyridin-3-yl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-760
5-cyanopyridin-3-yl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-761
4-fluoropyridin-3-yl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-762
4-chloropyridin-3-yl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-763
4-bromopyridin-3-yl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-764
4-iodopyridin-3-yl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-765
4-(trifluoromethyl) pyridin-3-yl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-766
4-nitropyridin-3-yl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-767
4-cyanopyridin-3-yl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-768
2,6-dichloropyridin-3-yl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-769
pyridin-3-yl N-oxide
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-770
pyridin-4-yl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-771
2-chloropyridin-4-yl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-772
3-bromopyridin-4-yl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-773
3,5-dichloropyridin-4-yl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-774
3-(trifluoromethyl) pyridin-4-yl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-775
2,6-dicyanopyridin-3-yl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-776
pyridin-4-yl N-oxide
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-777
pyridin-2-yl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-778
3-chloropyridin-2-yl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-779
4-bromopyridin-2-yl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-780
5-iodopyridin-2-yl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-781
6-chloropyridin-2-yl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-782
4-cyanopyridin-2-yl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-783
phenyl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-784
2-flourophenyl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-785
3-flourophenyl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-786
4-flourophenyl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-787
2-chlorophenyl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-788
3-chlorophenyl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-789
4-chlorophenyl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-790
2-bromophenyl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-791
3-bromophenyl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-792
4-bromophenyl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-793
2-iodophenyl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-794
3-iodophenyl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-795
4-iodophenyl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-796
(2-trifluoromethyl) phenyl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-797
(3-trifluoromethyl) phenyl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-798
(4-trifluoromethyl) phenyl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-799
2-nitrophenyl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-800
3-nitrophenyl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-801
4-nitrophenyl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-802
2-cyanophenyl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-803
3-cyanophenyl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-804
4-cyanophenyl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-805
2,6-difluorophenyl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-806
3,4-dichlorophenyl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-807
2,4-dichlorophenyl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-808
2-chloro-4-fluorophenyl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-809
2-chloro-4,5-difluorophenyl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-810
4-bromo-2-chlorophenyl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-811
2-bromo-4-chlorophenyl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-812
2-bromo-4-fluorophenyl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-813
2-chloro-4-nitrophenyl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-814
3,5-dicyanophenyl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-815
4-cyano-2-fluorophenyl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-816
2-chloro-4-cyanophenyl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-817
pyridin-3-yl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-818
2-fluoropyridin-3-yl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-819
2-chloropyridin-3-yl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-820
2-bromopyridin-3-yl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-821
2-iodopyridin-3-yl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-822
2-(trifluoromethyl) pyridin-3-yl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-823
2-nitropyridin-3-yl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-824
2-cyanopyridin-3-yl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-825
6-fluoropyridin-3-yl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-826
6-chloropyridin-3-yl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-827
6-bromopyridin-3-yl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-828
6-iodopyridin-3-yl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-829
6-(trifluoromethyl) pyridin-3-yl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-830
6-nitropyridin-3-yl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-831
6-cyanopyridin-3-yl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-832
5-fluoropyridin-3-yl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-833
5-chloropyridin-3-yl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-834
5-bromopyridin-3-yl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-835
5-iodopyridin-3-yl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-836
5-(trifluoromethyl) pyridin-3-yl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-837
5-nitropyridin-3-yl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-838
5-cyanopyridin-3-yl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-839
4-fluoropyridin-3-yl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-840
4-chloropyridin-3-yl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-841
4-bromopyridin-3-yl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-842
4-iodopyridin-3-yl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-843
4-(trifluoromethyl) pyridin-3-yl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-844
4-nitropyridin-3-yl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-845
4-cyanopyridin-3-yl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-846
2,6-dichloropyridin-3-yl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-847
pyridin-3-yl N-oxide
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-848
pyridin-4-yl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-849
2-chloropyridin-4-yl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-850
3-bromopyridin-4-yl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-851
3,5-dichloropyridin-4-yl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-852
3-(trifluoromethyl) pyridin-4-yl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-853
2,6-dicyanopyridin-4-yl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-854
pyridin-4-yl N-oxide
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-855
pyridin-2-yl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-856
3-chloropyridin-2-yl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-857
4-bromopyridin-2-yl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-858
5-iodopyridin-2-yl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-859
6-chloropyridin-2-yl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-860
4-cyanopyridin-2-yl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-861
phenyl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-862
2-flourophenyl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-863
3-fluorophenyl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-864
4-fluorophenyl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-865
2-chlorophenyl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-866
3-chlorophenyl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-867
4-chlorophenyl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-868
2-bromophenyl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-869
3-bromophenyl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-870
4-bromophenyl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-871
2-iodophenyl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-872
3-iodophenyl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-873
4-iodophenyl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-874
(2-trifluoromethyl) phenyl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-875
(3-trifluoromethyl) phenyl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-876
(4-trifluoromethyl) phenyl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-877
2-nitrophenyl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-878
3-nitrophenyl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-879
4-nitrophenyl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-880
2-cyanophenyl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-881
3-cyanophenyl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-882
4-cyanophenyl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-883
2,6-difluorophenyl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-884
3,4-dichlorophenyl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-885
2,4-dichlorophenyl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-886
2-chloro-4-fluorophenyl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-887
2-chloro-4,5-difluorophenyl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-888
4-bromo-2-chlorophenyl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-889
2-bromo-4-chlorophenyl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-890
2-bromo-4-fluorophenyl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-891
2-chloro-4-nitrophenyl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-892
3,5-dicyanophenyl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-893
4-cyano-2-fluorophenyl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-894
2-chloro-4-cyanophenyl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-895
pyridin-3-yl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-896
2-fluoropyridin-3-yl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-897
2-chloropyridin-3-yl
H
H
H
CN
H
H
I
H
nonafluoro-2-9utyl
H
CF3


1-898
2-bromopyridin-3-yl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-899
2-iodopyridin-3-yl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-900
(2-trifluoromethyl) pyridin-3-yl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-901
2-nitropyridin-3-yl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-902
2-cyanopyridin-3-yl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-903
6-fluoropyridin-3-yl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-904
6-chloropyridin-3-yl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-905
6-bromopyridin-3-yl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-906
6-iodopyridin-3-yl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-907
6-(trifluoromethyl) pyridin-3-yl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-908
6-nitropyridin-3-yl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-909
6-cyanopyridin-3-yl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-910
5-fluoropyridin-3-yl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-911
5-chloropyridin-3-yl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-912
5-bromopyridin-3-yl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-913
5-iodopyridin-3-yl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-914
5-(trifluoromethyl) pyridin-3-yl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-915
5-nitropyridin-3-yl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-916
5-cyanopyridin-3-yl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-917
4-fluoropyridin-3-yl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-918
4-chloropyridin-3-yl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-919
4-bromopyridin-3-yl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-920
4-iodopyridin-3-yl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-921
4-(trifluoromethyl) pyridin-3-yl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-922
4-nitropyridin-3-yl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-923
4-cyanopyridin-3-yl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-924
2,6-dichloropyridin-3-yl
H
H
H
CN
H
H
I
H
nonafluoro-2-9utyl
H
CF3


1-925
pyridin-3-yl N-oxide
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-926
pyridin-4-yl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-927
2-chloropyridin-4-yl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-928
3-bromopyridin-4-yl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-929
3,5-dichloropyridin-4-yl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-930
3-(trifluoromethyl) pyridin-4-yl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-931
2,6-dicyanopyridin-4-yl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-932
pyridin-4-yl N-oxide
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-933
pyridin-2-yl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-934
3-chloropyridin-2-yl
H
H
H
CN
H
F1
I
H
nonafluoro-2-butyl
H
CF3


1-935
4-bromopyridin-2-yl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
C F3


1-936
5-iodopyridin-2-yl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-937
6-chloropyridin-2-yl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-938
4-cyanopyridin-2-yl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-939
phenyl
H
H
H
CN
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


1-954
3-cyanophenyl
H
H
H
CN
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


1-955
4-cyanophenyl
H
H
H
CN
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


1-970
2-chloropyridin-3-yl
H
H
H
CN
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


1-995
phenyl
H
H
H
CN
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


1-1010
3-cyanophenyl
H
H
H
CN
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


1-1011
4-cyanophenyl
H
H
H
CN
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


1-1026
2-chloropyridin-3-yl
H
H
H
CN
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


1-1051
phenyl
H
H
H
CN
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


1-1066
3-cyanophenyl
H
H
H
CN
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


1-1067
4-cyanophenyl
H
H
H
CN
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


1-1082
2-chloropyridin-3-yl
H
H
H
CN
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


1-1107
phenyl
H
H
H
CN
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


1-1122
3-cyanophenyl
H
H
H
CN
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


1-1123
4-cyanophenyl
H
H
H
CN
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


1-1138
2-chloropyridin-3-yl
H
H
H
CN
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


1-1163
phenyl
H
H
H
CN
H
H
CF3
H
heptafluoroisopropyl
H
CF3


1-1175
4-iodophenyl
H
H
H
CN
H
H
CF3
H
pentafluoroethyl
H
CF3


1-1177
(3-trifluoromethyl) phenyl
H
H
H
CN
H
H
C2F5
H
heptafluoroisopropyl
H
CF3


1-1183
3-cyanophenyl
H
H
H
CN
H
H
CF3
H
heptafluoroisopropyl
H
CF3


1-1184
4-cyanophenyl
H
H
H
CN
H
H
CF3
H
heptafluoroisopropyl
H
CF3


1-1190
4-bromo-2-chlorophenyl
H
H
H
CN
H
H
n-C3F7
H
heptafluoroisopropyl
H
CF3


1-1195
4-cyano-2-fluorophenyl
H
H
H
CN
H
H
i-C3F7
H
heptafluoroisopropyl
H
CF3


1-1199
2-chloropyridin-3-yl
H
H
H
CN
H
H
CF3
H
heptafluoroisopropyl
H
CF3


1-1200
2-bromopyridin-3-yl
H
H
H
CN
H
H
C2F5
H
heptafluoroisopropyl
H
C2F5


1-1211
6-cyanopyridin-3-yl
H
H
H
CN
H
H
C2F5
H
heptafluoroisopropyl
H
n-C3F7


1-1215
4-cyanopyridin-3-yl
H
H
H
CN
H
H
C2F5
H
heptafluoroisopropyl
H
i-C3F7


1-1231
phenyl
H
H
H
CN
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


1-1243
4-iodophenyl
H
H
H
CN
H
H
C2F5
H
nonafluoro-2-butyl
H
CF3


1-1251
3-cyanophenyl
H
H
H
CN
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


1-1252
4-cyanophenyl
H
H
H
CN
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


1-1258
4-bromo-2-chlorophenyl
H
H
H
CN
H
H
n-C3F7
H
nonafluoro-2-butyl
H
CF3


1-1263
4-cyano-2-fluorophenyl
H
H
H
CN
H
H
i-C3F7
H
nonafluoro-2-butyl
H
CF3


1-1267
2-chloropyridin-3-yl
H
H
H
CN
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


1-1268
2-bromopyridin-3-yl
H
H
H
CN
H
H
C2F5
H
nonafluoro-2-butyl
H
C2F5


1-1279
6-cyanopyridin-3-yl
H
H
H
CN
H
H
C2F5
H
nonafluoro-2-butyl
H
n-C3F7


1-1283
4-cyanopyridin-3-yl
H
H
H
CN
H
H
C2F5
H
nonafluoro-2-butyl
H
i-C3F7


1-1299
phenyl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


1-1319
3-cyanophenyl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


1-1320
4-cyanophenyl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


1-1335
2-chloropyridin-3-yl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


1-1377
phenyl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


1-1384
3-bromophenyl
H
H
H
CN
H
H
F
H
nonafluoro-2-butyl
H
OCF3


1-1397
3-cyanophenyl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


1-1398
4-cyanophenyl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


1-1413
2-chloropyridin-3-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


1-1455
phenyl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
OCF3


1-1475
3-cyanophenyl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
OCF3


1-1476
4-cyanophenyl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
OCF3


1-1491
2-chloropyridin-3-yl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
OCF3


1-1533
phenyl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


1-1553
3-cyanophenyl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


1-1554
4-cyanophenyl
H
H
F
CN
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


1-1569
2-chloropyridin-3-yl
H
H
F
CN
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


1-1611
phenyl
H
H
F
CN
H
H
I
H
heptafluoroisopropyl
H
OCF3


1-1631
3-cyanophenyl
H
H
F
CN
H
H
I
H
heptafluoroisopropyl
H
OCF3


1-1632
4-cyanophenyl
H
H
F
CN
H
H
I
H
heptafluoroisopropyl
H
OCF3


1-1647
2-chloropyridin-3-yl
H
H
F
CN
H
H
I
H
heptafluoroisopropyl
H
OCF3


1-1689
phenyl
H
H
F
CN
H
H
I
H
nonafluoro-2-butyl
H
OCF3


1-1709
3-cyanophenyl
H
H
F
CN
H
H
I
H
nonafluoro-2-butyl
H
OCF3


1-1710
4-cyanophenyl
H
H
F
CN
H
H
I
H
nonafluoro-2-butyl
H
OCF3


1-1725
2-chloropyridin-3-yl
H
H
F
CN
H
H
I
H
nonafluoro-2-butyl
H
OCF3


1-1767
phenyl
H
H
F
CN
H
H
F
H
heptafluoroisopropyl
H
CF3


1-1768
phenyl
H
H
F
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-1788
3-cyanophenyl
H
H
F
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-1789
4-cyanophenyl
H
H
F
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-1804
2-ehloropyridin-3-yl
H
H
F
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


1-1846
phenyl
H
H
F
CN
H
H
F
H
nonafluoro-2-butyl
H
CF3


1-1847
phenyl
H
H
F
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-1867
3-cyanophenyl
H
H
F
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-1868
4-cyanophenyl
H
H
F
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-1883
2-chloropyridin-3-yl
H
H
F
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-1925
phenyl
H
H
F
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-1945
3-cyanophenyl
H
H
F
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-1946
4-cyanophenyl
H
H
F
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-1961
2-chloropyridin-3-yl
H
H
F
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-1968
6-chloropyridin-3-yl
H
H
F
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


1-2003
phenyl
H
H
F
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-2023
3-cyanophenyl
H
H
F
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-2024
4-cyanophenyl
H
H
F
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-2039
2-chloropyridin-3-yl
H
H
F
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


1-2081
phenyl
H
H
F
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-2101
3-cyanophenyl
H
H
F
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-2102
4-cyanophenyl
H
H
F
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-2117
2-chloropyridin-3-yl
H
H
F
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


1-2159
phenyl
H
H
F
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-2179
3-cyanophenyl
H
H
F
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-2180
4-cyanophenyl
H
H
F
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-2195
2-chloropyridin-3-yl
H
H
F
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


1-2237
phenyl
H
H
F
CN
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


1-2252
3-cyanophenyl
H
H
F
CN
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


1-2253
4-cyanophenyl
H
H
F
CN
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


1-2268
2-chloropyridin-3-yl
H
H
F
CN
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


1-2293
phenyl
H
H
F
CN
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


1-2309
3-cyanophenyl
H
H
F
CN
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


1-2324
4-cyanophenyl
H
H
F
CN
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


1-2325
2-chloropyridin-3-yl
H
H
F
CN
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


1-2349
phenyl
H
H
F
CN
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


1-2364
3-cyanophenyl
H
H
F
CN
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


1-2365
4-cyanophenyl
H
H
F
CN
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


1-2380
2-chloropyridin-3-yl
H
H
F
CN
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


1-2405
phenyl
H
H
F
CN
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


1-2420
3-cyanophenyl
H
H
F
CN
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


1-2421
4-cyanophenyl
H
H
F
CN
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


1-2436
2-chloropyridin-3-yl
H
H
F
CN
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


1-2461
phenyl
H
H
F
CN
H
H
CF3
H
heptafluoroisopropyl
H
CF3


1-2481
3-cyanophenyl
H
H
F
CN
H
H
CF3
H
heptafluoroisopropyl
H
CF3


1-2482
4-cyanophenyl
H
H
F
CN
H
H
CF3
H
heptafluoroisopropyl
H
CF3


1-2497
2-chloropyridin-3-yl
H
H
F
CN
H
H
CF3
H
heptafluoroisopropyl
H
CF3


1-2529
phenyl
H
H
F
CN
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


1-2549
3-cyanophenyl
H
H
F
CN
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


1-2550
4-cyanophenyl
H
H
F
CN
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


1-2565
2-chloropyridin-3-yl
H
H
F
CN
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


1-2597
phenyl
H
H
F
CN
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


1-2617
3-cyanophenyl
H
H
F
CN
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


1-2618
4-cyanophenyl
H
H
F
CN
F
H
Cl
H
heptafluoroisopropyl
H
OCF3


1-2633
2-chloropyridin-3-yl
H
H
F
CN
F
H
Cl
H
heptafluoroisopropyl
H
OCF3


1-2675
phenyl
H
H
F
CN
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


1-2695
3-cyanophenyl
H
H
F
CN
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


1-2696
4-cyanophenyl
H
H
F
CN
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


1-2711
2-chloropyridin-3-yl
H
H
F
CN
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


1-2753
phenyl
H
H
F
CN
F
H
Br
H
heptafluoroisopropyl
H
OCF3


1-2773
3-cyanophenyl
H
H
F
CN
F
H
Br
H
heptafluoroisopropyl
H
OCF3


1-2774
4-cyanophenyl
H
H
F
CN
F
H
Br
H
heptafluoroisopropyl
H
OCF3


1-2789
2-chloropyridin-3-yl
H
H
F
CN
F
H
Br
H
heptafluoroisopropyl
H
OCF3


1-2831
phenyl
H
H
F
CN
F
H
Br
H
nonafluoro-2-butyl
H
OCF3


1-2851
3-cyanophenyl
H
H
F
CN
F
H
Br
H
nonafluoro-2-butyl
H
OCF3


1-2852
4-cyanophenyl
H
H
F
CN
F
H
Br
H
nonafluoro-2-butyl
H
OCF3


1-2867
2-chloropyridin-3-yl
H
H
F
CN
F
H
Br
H
nonafluoro-2-butyl
H
OCF3


1-2909
phenyl
H
H
F
CN
F
H
I
H
heptafluoroisopropyl
H
OCF3


1-2929
3-cyanophenyl
H
H
F
CN
F
H
I
H
heptafluoroisopropyl
H
OCF3


1-2930
4-cyanophenyl
H
H
F
CN
F
H
I
H
heptafluoroisopropyl
H
OCF3


1-2945
2-chloropyridin-3-yl
H
H
F
CN
F
H
I
H
heptafluoroisopropyl
H
OCF3


1-2987
phenyl
H
H
F
CN
F
H
I
H
nonafluoro-2-butyl
H
OCF3


1-3007
3-cyanophenyl
H
H
F
CN
F
H
I
H
nonafluoro-2-butyl
H
OCF3


1-3008
4-cyanophenyl
H
H
F
CN
F
H
I
H
nonafluoro-2-butyl
H
OCF3


1-3023
2-chloropyridin-3-yl
H
H
F
CN
F
H
I
H
nonafluoro-2-butyl
H
OCF3


1-3065
phenyl
H
H
F
CN
F
H
F
H
heptafluoroisopropyl
H
CF3


1-3066
phenyl
H
H
F
CN
F
H
Cl
H
heptafluoroisopropyl
H
CF3


1-3086
3-cyanophenyl
H
H
F
CN
F
H
Cl
H
heptafluoroisopropyl
H
CF3


1-3087
4-cyanophenyl
H
H
F
CN
F
H
Cl
H
heptafluoroisopropyl
H
CF3


1-3102
2-chloropyridin-3-yl
H
H
F
CN
F
H
Cl
H
heptafluoroisopropyl
H
CF3


1-3144
phenyl
H
H
F
CN
F
H
F
H
nonafluoro-2-butyl
H
CF3


1-3145
phenyl
H
H
F
CN
F
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-3165
3-cyanophenyl
H
H
F
CN
F
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-3166
4-cyanophenyl
H
H
F
CN
F
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-3181
2-chloropyridin-3-yl
H
H
F
CN
F
H
Cl
H
nonafluoro-2-butyl
H
CF3


1-3223
phenyl
H
H
F
CN
F
H
Br
H
heptafluoroisopropyl
H
CF3


1-3243
3-cyanophenyl
H
H
F
CN
F
H
Br
H
heptafluoroisopropyl
H
CF3


1-3244
4-cyanophenyl
H
H
F
CN
F
H
Br
H
heptafluoroisopropyl
H
CF3


1-3259
2-chloropyridin-3-yl
H
H
F
CN
F
H
Br
H
heptafluoroisopropyl
H
CF3


1-3301
phenyl
H
H
F
CN
F
H
Br
H
nonafluoro-2-butyl
H
CF3


1-3321
3-cyanophenyl
H
H
F
CN
F
H
Br
H
nonafluoro-2-butyl
H
CF3


1-3322
4-cyanophenyl
H
H
F
CN
F
H
Br
H
nonafluoro-2-butyl
H
CF3


1-3337
2-chloropyridin-3-yl
H
H
F
CN
F
H
Br
H
nonafluoro-2-butyl
H
CF3


1-3379
phenyl
H
H
F
CN
F
H
I
H
heptafluoroisopropyl
H
CF3


1-3399
3-cyanophenyl
H
H
F
CN
F
H
I
H
heptafluoroisopropyl
H
CF3


1-3400
4-cyanophenyl
H
H
F
CN
F
H
I
H
heptafluoroisopropyl
H
CF3


1-3415
2-chloropyridin-3-yl
H
H
F
CN
F
H
I
H
heptafluoroisopropyl
H
CF3


1-3457
phenyl
H
H
F
CN
F
H
I
H
nonafluoro-2-butyl
H
CF3


1-3477
3-cyanophenyl
H
H
F
CN
F
H
I
H
nonafluoro-2-butyl
H
CF3


1-3478
4-cyanophenyl
H
H
F
CN
F
H
I
H
nonafluoro-2-butyl
H
CF3


1-3493
2-chloropyridin-3-yl
H
H
F
CN
F
H
I
H
nonafluoro-2-butyl
H
CF3


1-3535
phenyl
H
H
F
CN
F
H
OCF3
H
heptafluoroisopropyl
H
OCF3


1-3550
3-cyanophenyl
H
H
F
CN
F
H
OCF3
H
heptafluoroisopropyl
H
OCF3


1-3551
4-cyanophenyl
H
H
F
CN
F
H
OCF3
H
heptafluoroisopropyl
H
OCF3


1-3566
2-chloropyridin-3-yl
H
H
F
CN
F
H
OCF3
H
heptafluoroisopropyl
H
OCF3


1-3591
phenyl
H
H
F
CN
F
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


1-3606
3-cyanophenyl
H
H
F
CN
F
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


1-3607
4-cyanophenyl
H
H
F
CN
F
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


1-3622
2-chloropyridin-3-yl
H
H
F
CN
F
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


1-3647
phenyl
H
H
F
CN
F
H
CF3
H
heptafluoroisopropyl
H
OCF3


1-3662
3-cyanophenyl
H
H
F
CN
F
H
CF3
H
heptafluoroisopropyl
H
OCF3


1-3663
4-cyanophenyl
H
H
F
CN
F
H
CF3
H
heptafluoroisopropyl
H
OCF3


1-3678
2-chloropyridin-3-yl
H
H
F
CN
F
H
CF3
H
heptafluoroisopropyl
H
OCF3


1-3703
phenyl
H
H
F
CN
F
H
CF3
H
nonafluoro-2-butyl
H
OCF3


1-3718
3-cyanophenyl
H
H
F
CN
F
H
CF3
H
nonafluoro-2-butyl
H
OCF3


1-3719
4-cyanophenyl
H
H
F
CN
F
H
CF3
H
nonafluoro-2-butyl
H
OCF3


1-3734
2-chloropyridin-3-yl
H
H
F
CN
F
H
CF3
H
nonafluoro-2-butyl
H
OCF3


1-3759
phenyl
H
H
F
CN
F
H
CF3
H
heptafluoroisopropyl
H
CF3


1-3779
3-cyanophenyl
H
H
F
CN
F
H
CF3
H
heptafluoroisopropyl
H
CF3


1-3780
4-cyanophenyl
H
H
F
CN
F
H
CF3
H
heptafluoroisopropyl
H
CF3


1-3795
2-chloropyridin-3-yl
H
H
F
CN
F
H
CF3
H
heptafluoroisopropyl
H
CF3


1-3827
phenyl
H
H
F
CN
F
H
CF3
H
nonafluoro-2-butyl
H
CF3


1-3847
3-cyanophenyl
H
H
F
CN
F
H
CF3
H
nonafluoro-2-butyl
H
CF3


1-3848
4-cyanophenyl
H
H
F
CN
F
H
CF3
H
nonafluoro-2-butyl
H
CF3


1-3863
2-chloropyridin-3-yl
H
H
F
CN
F
H
CF3
H
nonafluoro-2-butyl
H
CF3











embedded image





















TABLE 2





compound














number
Q1
R1
R2
X1
X2
X3
X4
Y1
Y2
Y3
Y4
Y5







2-1
phenyl
Me
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


2-21
3-cyanophenyl
Me
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


2-22
4-cyanophenyl
Me
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


2-37
2-chloropyridin-3-yl
Me
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


2-79
phenyl
Me
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


2-99
3-cyanophenyl
Me
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


2-100
4-cyanophenyl
Me
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


2-115
2-chloropyridin-3-yl
Me
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


2-157
phenyl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
OCF3


2-177
3-cyanophenyl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
OCF3


2-178
4-cyanophenyl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
OCF3


2-193
2-chloropyridin-3-yl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
OCF3


2-235
phenyl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


2-255
3-cyanophenyl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


2-256
4-cyanophenyl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


2-271
2-chloropyridin-3-yl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


2-313
phenyl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
OCF3


2-333
3-cyanophenyl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
OCF3


2-334
4-cyanophenyl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
OCF3


2-349
2-chloropyridin-3-yl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
OCF3


2-391
phenyl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
OCF3


2-411
3-cyanophenyl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
OCF3


2-412
4-cyanophenyl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
OCF3


2-427
2-chloropyridin-3-yl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
OCF3


2-469
phenyl
Me
H
H
CN
H
H
F
H
heptafluoroisopropyl
H
CF3


2-470
phenyl
Me
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


2-481
3-iodophenyl
Me
H
H
CN
H
H
Cl
H
pentafluoroethyl
H
CF3


2-482
4-iodophenyl
Me
H
H
CN
H
H
Cl
H
pentafluoroethyl
H
CF3


2-484
(3-trifluoromethyl) phenyl
Et
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


2-489
2-cyanophenyl
Me
H
H
CN
H
H
Cl
H
pentafluoroethyl
H
C2F5


2-490
3-cyanophenyl
Me
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


2-491
4-cyanophenyl
Me
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


2-494
2,4-dichlorophenyl
Me
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
C2F5


2-495
2-chloro-4-fluorophenyl
n-Pr
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


2-498
2-bromo-4-chlorophenyl
Me
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


2-505
2-fluoropyridin-3-yl
Me
H
H
CN
H
H
Cl
H
pentafluoroethyl
H
CF3


2-506
2-chloropyridin-3-yl
Me
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


2-512
6-fluoropydin-3-yl
i-Pr
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


2-513
6-chloropyridin-3-yl
Me
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


2-518
6-cyanopyridin-3-yl
Me
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


2-519
5-fluoropyridin-3-yl
Me
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
C2F5


2-521
5-bromopyridin-3-yl
Me
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


2-522
5-iodopyridin-3-yl
Me
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
i-C3F7


2-524
5-nitropyridin-3-yl
Me
H
H
CN
H
H
Cl
H
pentafluoroethyl
H
CF3


2-526
4-fluoropyridin-3-yl
Me
H
H
CN
H
H
Cl
H
pentafluoroethyl
H
CF3


2-528
4-bromopyridin-3-yl
CH2CH═CH2
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


2-529
4-iodopyridin-3-yl
Me
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
i-C3F7


2-535
pyridin-4-yl
CN
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


2-547
4-cyanopyridin-2-yl
Me
H
H
CN
H
H
Cl
H
pentafluoroethyl
H
CF3


2-548
phenyl
Me
H
H
CN
H
H
F
H
nonafluoro-2-butyl
H
CF3


2-549
phenyl
Me
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


2-556
2-bromophenyl
CH2C═CH
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


2-562
(2-triflouromethyl) phenyl
Me
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


2-563
(3-triflouromethyl) phenyl
NH2
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


2-569
3-cyanophenyl
Me
H
H
CN
H
H
Cl
H
nona5uoro-2-butyl
H
CF3


2-570
4-cyanophenyl
Me
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


2-576
4-bromo-2-chlorophenyl
C(O)OMe
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


2-579
2-chloro-4-nitrophenyl
Me
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


2-585
2-chloropyridin-3-yl
Me
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


2-596
6-nitropyridin-3-y'
C(O)OEt
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


2-598
5-fluoropyridin-3-yl
Me
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


2-600
5-bromopyridin-3-yl
Me
H
H
CN
H
H
Cl
H
nona5uoro-2-butyl
H
n-C3F7


2-601
5-iodopydin-3-yl
Me
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


2-605
4-fluoropyridin-3-yl
Me
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


2-607
4-bromopyridin-3-yl
C(O)C(O)Me
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


2-609
4-(trifluoromethyl) pyridin-3-yl
Me
H
H
CN
H
H
Cl
H
nona9uoro-2-butyl
H
n-C3F7


2-610
4-nitropyridin-3-yl
C(O)O(O)Et
H
H
CN
H
H
Cl
H
nona5uoro-2-butyl
H
i-C3F7


2-623
4-bromopyridin-2-yl
C(O)Me
H
H
CN
H
H
Cl
H
nona5uoro-2-butyl
H
CF3


2-625
6-chloropyridin-2-yl
C(O)Et
H
H
CN
H
H
Cl
H
nona5uoro-2-butyl
H
CF3


2-626
4-cyanopyridin-2-yl
Me
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


2-627
phenyl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-628
2-fluorophenyl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-629
3-fluorophenyl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-630
4-fluorophenyl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-631
2-chlorophenyl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-632
3-chlorophenyl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-633
4-chlorophenyl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-634
2-bromophenyl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-635
3-bromophenyl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-636
4-bromophenyl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-637
2-iodophenyl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-638
3-iodophenyl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-639
4-iodophenyl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-640
(2-trifluoromethyl) phenyl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-641
(3-trifluoromethyl) phenyl
S(O)2Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-642
(4-trifluoromethyl) phenyl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-643
2-nitrophenyl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-644
3-nitropheeyl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-645
4-nitrophenyl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-646
2-cyanophenyl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-647
3-cyanophenyl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-648
4-cyanophenyl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-649
2,6-difluorophenyl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-650
3,4-dichlorophenyl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-651
2,4-dichlorophenyl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-652
2-chloro-4-fluorophenyl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-653
2-chloro-4,5-difluorophenyl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-654
4-bromo-4-chlorophenyl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-655
2-bromo-4-chlorophenyl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-656
2-bromo-4-fluorophenyl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-657
2-chloro-4-nitrophenyl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-658
3,5-dicyanophenyl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-659
4-cyano-2-fluorophenyl
S(O)2Et
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-660
2-chloro-4-cyanophenyl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-661
pyridin-3-yl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-662
2-fluoropyridin-3-yl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-663
2-chloropyridin-3-yl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-664
2-bromopyridin-3-yl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-665
2-iodopyridin-3-yl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-666
2-(trifluoromethyl) pyridin-3-yl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-667
2-nitropyridin-3-yl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-668
2-cyanopyridin-3-yl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-669
6-fluoropyridin-3-yl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-670
6-chloropyridin-3-yl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-671
6-bromopyridin-3-yl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-672
6-iodopyridin-3-yl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-673
6-(trifluoromethyl) pyridin-3-yl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-674
6-nitropyridin-3-yl
CH2Ph
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-675
6-cyanopyridin-3-yl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-676
5-fluoropyridin-3-yl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-677
5-chloropyridin-3-yl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-678
5-bromopyridin-3-yl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-679
5-iodopyridin-3-yl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-680
5-(trifluoromethyl) pyridin-3-yl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-681
5-nitropyridin-3-yl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-682
5-cyanopyridin-3-yl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-683
4-fluoropyri4in-3-yl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-684
4-chloropyridin-3-yl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-685
4-bromopyridin-3-yl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-686
4-iodopyridin-3-yl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-687
4-(trifluoromethyl) pyridin-3-yl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-688
4-nitropyridin-3-yl
CH2(3-Py)
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-689
4-cyanopyridin-3-yl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-690
2,6-dichloropyridin-3-yl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-691
pyridin-3-yl N-oxide
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-692
pyridin-4-yl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-693
2-chloropyridin-4-yl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-694
3-bromopyridin-4-yl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-695
3,5-dichloropyridin-4-yl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-696
3-(trifluoromethyl) pyridin-4-yl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-697
2,6-dicyanopyridin-4-yl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-698
pyridin-4-yl N-oxide
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-699
pyridin-2-yl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-700
3-chloropyridin-2-yl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-701
4-bromopyridin-2-yl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-702
5-iodopyridin-2-yl
CH2(3-Py-N-
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3




oxide)
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-703
6-chloropyridin-2-yl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-704
4-cyanopyridin-2-yl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-705
phenyl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-706
2-fluorophenyl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-707
3-fluorophenyl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-708
4-fluorophenyl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-709
2-chlorophenyl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-710
3-chlorophenyl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-711
4-chlorophenyl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-712
2-bromophenyl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-713
3-bromophenyl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-714
4-bromophenyl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-715
2-iodophenyl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-716
3-iodophenyl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-717
4-iodophenyl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-718
(2-trifluoromethyl) phenyl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-719
(3-trifluoromethyl) phenyl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-720
(4-trifluoromethyl) phenyl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-721
2-nitrophenyl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-722
3-nitrophenyl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-723
4-nitrophenyl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-724
2-cyanophenyl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-725
3-cyanophenyl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-726
4-cyanophenyl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-727
2,6-difluorophenyl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-728
3,4-dichlorophenyl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-729
2,4-dichlorophenyl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-730
2-chloro-4-fluorophenyl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-731
2-chloro-4,5-difluorophenyl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-732
4-bromo-2-chlorophenyl
Et
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-733
2-bromo-4-chlorophenyl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-734
4-bromo-4-fluorophenyl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-735
2-chloro-4-nitrophenyl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-736
3,5-dicyanophenyl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-737
4-cyano-2-flurophenyl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-738
2-chloro-4-cyanophenyl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-739
pyridin-3-yl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-740
2-fluoropyridin-3-yl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-741
2-chloropyridin-3-yl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-742
2-bromopyridin-3-yl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-743
2-iodopyndin-3-yl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-744
2-(trifluoromethyl) pyridin-3-yl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-745
2-nitropyridin-3-yl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-746
2-cyanopyridin-3-yl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-747
6-fluoropyridin-3-yl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-748
6-chloropyridin-3-yl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-749
6-bromopyridin-3-yl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-750
6-iodopyridin-3-yl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-751
6-(trifluoromethyl) pyridin-3-yl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-752
6-nitropyridin-3-yl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-753
6-cyanopyridin-3-yl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-754
5-fluoropyridin-3-yl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-755
5-chloropyridin-3-yl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-756
5-bromopyridin-yl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-757
5-iodopyridin-3-yl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-758
5-(trifluoromethyl) pyridin-3-yl
CN
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-759
5-nitropyridin-3-yl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-760
5-cyanopyridin-3-yl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-761
4-fluoropyridin-3-yl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-762
4-chloropyridin-3-yl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-763
4-bromopyridin-3-yl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-764
4-iodopyridin-3-yl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-765
4-(trifluoromethyl) pyridin-3-yl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-766
4-nitropyridin-3-yl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-767
4-cyanopyridin-3-yl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-768
2,6-dichloropyridin-3-yl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-769
pyridin-3-yl N-oxide
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-770
pyridin-4-yl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-771
2-chloropyridin-4-yl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-772
3-bromopyridin-4-yl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-773
3,5-dichloropyridin-4-yl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-774
3-(trifluoromethyl) pyridin-4-yl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-775
2,6-dicyanopyridin-4-yl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-776
pyridin-4-yl N-oxide
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-777
pyridin-2-yl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-778
3-chloropyridin-2-yl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-779
4-bromopyridin-2-yl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-780
5-iodopyridin-2-yl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-781
6-chloropyridin-2-yl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-782
4-cyanopyridin-2-yl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-783
phenyl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-784
2-flurophenyl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-785
3-flurophenyl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-786
4-flurophenyl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-787
2-chlorophenyl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-788
3-chlorophenyl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-789
4-chlorophenyl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-790
2-bromophenyl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-791
3-bromophenyl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-792
4-bromophenyl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-793
2-iodophenyl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-794
3-iodophenyl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-795
4-iodophenyl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-796
(2-trifluoromethyl) phenyl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-797
(3-trifluoromethyl) phenyl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-798
(4-trifluoromethyl) phenyl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-799
2-nitrophenyl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-800
3-nitrophenyl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-801
4-nitrophenyl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-802
2-cyanophenyl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-803
3-cyanophenyl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-804
4-cyanophenyl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-805
2,6-difluorophenyl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-806
3,4-dichlorophenyl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-807
2,4-dichlorophenyl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-808
2-chloro-4-fluorophenyl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-809
2-chloro-4,5-difluorophenyl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-810
4-bromo-2-chlorophenyl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-811
2-bromo-4-chlorophenyl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-812
2-bromo-4-fluorophenyl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-813
2-chloro-4-nitrophenyl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-814
3,5-dicyanophenyl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-815
4-cyano-2-fluorophenyl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-816
2-chloro-4-cyanophenyl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-817
pyridin-3-yl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-818
2-fluoropyridin-3-yl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-819
2-chloropyridin-3-yl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-820
2-bromopyridin-3-yl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-821
2-iodopyridin-3-yl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-822
2-(trifluoromethyl) pyridin-3-yl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-823
2-nitropyridin-3-yl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-824
2-cyanopyridin-yl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-825
6-fluoropyridin-3-yl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-826
6-chloropyridin-3-yl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-827
6-bromopyridin-3-yl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-828
6-iodopyridin-3-yl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-829
6-(trifluoromethyl) pyridin-3-yl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-830
6-nitropyridin-3-yl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-831
6-cyanopyridin-3-yl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-832
5-fluoropyridin-3-yl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-833
5-chloropyridin-3-yl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-834
5-bromopyridin-3-yl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-835
5-iodopyridin-3-yl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-836
5-(trifluoromethyl) pyridin-3-yl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-837
5-nitropyridin-3-yl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-838
5-cyanopyridin-3-yl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-839
4-fluoropyridin-3-yl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-840
4-chloropyridin-3-yl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-841
4-bromopyridin-3-yl
C(O)Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-842
4-iodopyridin-3-yl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-843
4-(trifluoromethyl) pyridin-3-yl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-844
4-nitropyridin-3-yl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-845
4-cyanopyridin-3-yl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-846
2,6-dichloropyridin-3-yl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-847
pyridin-3-yl N-oxide
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-848
pyridin-4-yl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-849
2-chloropyridin-4-yl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-850
3-bromopyridin-4-yl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-851
3,6-dichloropyridin-4-yl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-852
3-(trifluoromethyl) pyridin-4-yl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-853
2,6-dichloropyridin-4-yl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-854
pyridin-4-yl N-oxide
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-855
pyridin-2-yl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-856
3-chloropyridin-2-yl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-857
4-bromopyridin-2-yl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-858
5-iodopyridin-2-yl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-859
6-chloropyridin-2-yl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-860
4-cyanopyridin-2-yl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-861
phenyl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-862
2-fluorophenyl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-863
3-fluorophenyl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


8-864
4-fluorophenyl
Me
H
H
CH
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-865
2-chlorophenyl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-866
3-chlorophenyl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-867
4-chlorophenyl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-868
2-bromophenyl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-869
3-bromophenyl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-870
4-bromophenyl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-871
2-iodophenyl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-872
3-iodophenyl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-873
4-iodophenyl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-874
(2-trifluoromethyl) phenyl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-875
(3-trifluoromethyl) phenyl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-876
(4-trifluoromethyl) phenyl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-877
2-nitrophenyl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-878
3-nitrophenyl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-879
4-nrtrophenyl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-880
2-cyanophenyl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-881
3-cyanophenyl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-882
4-cyanophenyl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-883
2,6-difluorophenyl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-884
3,4-dichlorophenyl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-885
2,4-dichlorophenyl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-886
2-chloro-4-fluorophenyl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-887
2-chloro-4,5-difluorophenyl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-888
4-bromo-2-chlorophenyl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-889
2-bromo-4-chlorophenyl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-890
2-bromo-4-fluorophenyl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-891
2-chloro-4-nitrophenyl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-892
3,5-dicyanophenyl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-893
4-cyano-2-fluorophenyl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-894
2-chloro-4-cyanophenyl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-895
pyridin-3-yl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-896
2-fluoropyridin-3-yl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-897
2-chloropyridin-3-yl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-898
2-bromopyridin-3-yl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-899
2-iodopyridin-3-yl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-900
2-(trifluoromethyl) pyridin-3-yl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-901
2-nitropyridin-3-yl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-902
2-cyanopyridin-3-yl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-903
6-fluoropyridin-3-yl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-904
6-chloropyridin-3-yl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-905
6-bromopyridin-3-yl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-906
6-iodopyridin-3-yl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-907
6-(trifluoromethyl) pyridin-3-yl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-908
6-nitropyridin-3-yl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-909
6-cyanopyridin-3-yl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-910
5-fluoropyridin-3-yl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-911
5-chloropyridin-3-yl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-912
5-bromopyridin-3-yl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-913
5-iodopyridin-3-yl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-914
5-(trifluoromethyl) pyridin-3-yl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-915
5-nitropyridin-3-yl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-916
5-cyanopyridin-3-yl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-917
4-fluoropyridin-3-yl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-918
4-chloropyridin-3-yl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-919
4-bromopyridin-3-yl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-920
4-iodopyridin-3-yl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-921
4-(trifluoromethyl) pyridin-3-yl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-922
4-nitropyridin-3-yl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-923
4-cyanopyridin-3-yl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-924
2,6-dichloropyridin-3-yl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-925
pyridin-3-yl N-oxide
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-926
pyridin-4-yl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-927
2-chloropyridin-4-yl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-928
3-bromopyridin-4-yl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-929
3,5-dichloropyridin-4-yl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-930
3-(trifluoromethyl) pyridin-4-yl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-931
2,6-dicyanopyridin-4-yl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-932
pyridin-4-yl N-oxide
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-933
pyridin-2-yl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-934
3-chloropyridin-2-yl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-935
4-bromopyridin-2-yl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-936
5-iodopyridin-2-yl
Me
H
H
CN
H
H
I
H
nona8uoro-2-butyl
H
CF3


2-937
6-chloropyridin-2-yl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-938
4-cyanopyridin-2-yl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-939
phenyl
Me
H
H
CN
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


2-970
2-chloropyridin-3-yl
Me
H
H
CN
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


2-995
phenyl
Me
H
H
CN
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


2-1026
2-chloropyridin-3-yl
Me
H
H
CN
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


2-1051
phenyl
Me
H
H
CN
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


2-1082
2-chloropyridin-3-yl
Me
H
H
CN
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


2-1107
phenyl
Me
H
H
CN
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


2-1138
2-chloropyridin-3-yl
Me
H
H
CN
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


2-1163
phenyl
Me
H
H
CN
H
H
CF3
H
heptafluoroisopropyl
H
CF3


2-1183
3-cyanophenyl
Me
H
H
CN
H
H
CF3
H
heptafluoroisopropyl
H
CF3


2-1184
4-cyanophenyl
Me
H
H
CN
H
H
CF3
H
heptafluoroisopropyl
H
CF3


2-1199
2-chloropyridin-3-yl
Me
H
H
CN
H
H
CF3
H
heptafluoroisopropyl
H
CF3


2-1231
phenyl
Me
H
H
CN
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


2-1251
3-cyanophenyl
Me
H
H
CN
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


2-1252
4-cyanophenyl
Me
H
H
CN
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


2-1267
2-chloropyridin-3-yl
Me
H
H
CN
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


2-1299
phenyl
Me
H
F
CN
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


2-1319
3-cyanophenyl
Me
H
F
CN
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


2-1320
4-cyanophenyl
Me
H
F
CN
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


2-1335
2-chloropyridin-3-yl
Me
H
F
CN
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


2-1377
phenyl
Me
H
F
CN
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


2-1397
3-cyanophenyl
Me
H
F
CN
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


2-1398
4-cyanophenyl
Me
H
F
CN
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


2-1413
2-chloropyridin-3-yl
Me
H
F
CN
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


2-1455
phenyl
Me
H
F
CN
H
H
Br
H
heptafluoroisopropyl
H
OCF3


2-1475
3-cyanophenyl
Me
H
F
CN
H
H
Br
H
heptafluoroisopropyl
H
OCF3


2-1476
4-cyanophenyl
Me
H
F
CN
H
H
Br
H
heptafluoroisopropyl
H
OCF3


2-1491
2-chloropyridin-3-yl
Me
H
F
CN
H
H
Br
H
heptafluoroisopropyl
H
OCF3


2-1533
phenyl
Me
H
F
CN
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


2-1553
3-cyanophenyl
Me
H
F
CN
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


2-1554
4-cyanophenyl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


2-1569
2-chloropyridin-3-yl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


2-1611
phenyl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
OCF3


2-1631
3-cyanophenyl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
OCF3


2-1632
4-cyanophenyl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
OCF3


2-1647
2-chloropyridin-3-yl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
OCF3


2-1689
phenyl
Me
H
F
CN
H
H
I
H
nonafluoro-2-butyl
H
OCF3


2-1709
3-cyanophenyl
Me
H
F
CN
H
H
I
H
nonafluoro-2-butyl
H
OCF3


2-1710
4-cyanophenyl
Me
H
F
CN
H
H
I
H
nonafluoro-2-butyl
H
OCF3


2-1725
2-chloropyridin-3-yl
Me
H
F
CN
H
H
I
H
nonafluoro-2-butyl
H
OCF3


2-1767
phenyl
Me
H
F
CN
H
H
F
H
heptafluoroisopropyl
H
CF3


2-1768
phenyl
Me
H
F
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


2-1788
3-cyanophenyl
Me
H
F
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


2-1789
4-cyanophenyl
Me
H
F
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


2-1804
2-chloropyridin-3-yl
Me
H
F
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


2-1846
phenyl
Me
H
F
CN
H
H
F
H
nonafluoro-2-butyl
H
CF3


2-1847
phenyl
Me
H
F
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


2-1867
3-cyanophenyl
Me
H
F
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


2-1868
4-cyanophenyl
Me
H
F
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


2-1883
2-chloropyridin-3-yl
Me
H
F
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


2-1925
phenyl
Me
H
F
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-1945
3-cyanophenyl
Me
H
F
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-1946
4-cyanophenyl
Me
H
F
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-1961
2-chloropyridin-3-yl
Me
H
F
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


2-2003
phenyl
Me
H
F
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-2023
3-cyanophenyl
Me
H
F
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-2024
4-cyanophenyl
Me
H
F
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-2039
2-chloropyridin-3-yl
Me
H
F
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


2-2081
phenyl
Me
H
F
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-2101
3-cyanophenyl
Me
H
F
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-2102
4-cyanophenyl
Me
H
F
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-2117
2-chloropyridin-3-yl
Me
H
F
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


2-2159
phenyl
Me
H
F
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-2179
3-cyanophenyl
Me
H
F
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-2180
4-cyanophenyl
Me
H
F
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-2195
2-chloropyridin-3-yl
Me
H
F
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


2-2237
phenyl
Me
H
F
CN
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


2-2268
2-chloropyridin-3-yl
Me
H
F
CN
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


2-2293
phenyl
Me
H
F
CN
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


2-2324
2-chloropyridin-3-yl
Me
H
F
CN
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


2-2349
phenyl
Me
H
F
CN
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


2-2380
2-chloropyridin-3-yl
Me
H
F
CN
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


2-2405
phenyl
Me
H
F
CN
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


2-2436
2-chloropyridin-3-yl
Me
H
F
CN
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


2-2461
phenyl
Me
H
F
CN
H
H
CF3
H
heptafluoroisopropyl
H
CF3


2-2481
3-cyanophenyl
Me
H
F
CN
H
H
CF3
H
heptafluoroisopropyl
H
CF3


2-2482
4-cyanophenyl
Me
H
F
CN
H
H
CF3
H
heptafluoroisopropyl
H
CF3


2-2497
2-chloropyridin-3-yl
Me
H
F
CN
H
H
CF3
H
heptafluoroisopropyl
H
CF3


2-2529
phenyl
Me
H
F
CN
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


2-2549
3-cyanophenyl
Me
H
F
CN
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


2-2550
4-cyanophenyl
Me
H
F
CN
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


2-2565
2-chloropyridin-3-yl
Me
H
F
CN
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


2-2597
phenyl
Me
H
F
CN
F
H
Cl
H
heptafluoroisopropyl
H
OCF3


2-2617
3-cyanophenyl
Me
H
F
CN
F
H
Cl
H
heptafluoroisopropyl
H
OCF3


2-2618
4-cyanophenyl
Me
H
F
CN
F
H
Cl
H
heptafluoroisopropyl
H
OCF3


2-2633
2-chloropyridin-3-yl
Me
H
F
CN
F
H
Cl
H
heptafluoroisopropyl
H
OCF3


2-2675
phenyl
Me
H
F
CN
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


2-2695
3-cyanophenyl
Me
H
F
CN
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


2-2696
4-cyanophenyl
Me
H
F
CN
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


2-2711
2-chloropyridin-3-yl
Me
H
F
CN
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


2-2753
phenyl
Me
H
F
CN
F
H
Br
H
heptafluoroisopropyl
H
OCF3


2-2773
3-cyanophenyl
Me
H
F
CN
F
H
Br
H
heptafluoroisopropyl
H
OCF3


2-2774
4-cyanophenyl
Me
H
F
CN
F
H
Br
H
heptafluoroisopropyl
H
OCF3


2-2789
2-chloropyridin-3-yl
Me
H
F
CN
F
H
Br
H
heptafluoroisopropyl
H
OCF3


2-2831
phenyl
Me
H
F
CN
F
H
Br
H
nonafluoro-2-butyl
H
OCF3


2-2851
3-cyanophenyl
Me
H
F
CN
F
H
Br
H
nonafluoro-2-butyl
H
OCF3


2-2852
4-cyanophenyl
Me
H
F
CN
F
H
Br
H
nonafluoro-2-butyl
H
OCF3


2-2867
2-chloropyridin-3-yl
Me
H
F
CN
F
H
Br
H
nonafluoro-2-butyl
H
OCF3


2-2909
phenyl
Me
H
F
CN
F
H
I
H
heptafluoroisopropyl
H
OCF3


2-2929
3-cyanophenyl
Me
H
F
CN
F
H
I
H
heptafluoroisopropyl
H
OCF3


2-2930
4-cyanophenyl
Me
H
F
CN
F
H
I
H
heptafluoroisopropyl
H
OCF3


2-2945
2-chloropyridin-3-yl
Me
H
F
CN
F
H
I
H
heptafluoroisopropyl
H
OCF3


2-2987
phenyl
Me
H
F
CN
F
H
I
H
nonafluoro-2-butyl
H
OCF3


2-3007
3-cyanophenyl
Me
H
F
CN
F
H
I
H
nonafluoro-2-butyl
H
OCF3


2-3008
4-cyanophenyl
Me
H
F
CN
F
H
I
H
nonafluoro-2-butyl
H
OCF3


2-3023
2-chloropyridin-3-yl
Me
H
F
CN
F
H
I
H
nonafluoro-2-butyl
H
OCF3


2-3065
phenyl
Me
H
F
CN
F
H
F
H
heptafluoroisopropyl
H
CF3


2-3066
phenyl
Me
H
F
CN
F
H
Cl
H
heptafluoroisopropyl
H
CF3


2-3086
3-cyanophenyl
Me
H
F
CN
F
H
Cl
H
heptafluoroisopropyl
H
CF3


2-3087
4-cyanophenyl
Me
H
F
CN
F
H
Cl
H
heptafluoroisopropyl
H
CF3


2-3102
2-chloropyridin-3-yl
Me
H
F
CN
F
H
Cl
H
heptafluoroisopropyl
H
CF3


2-3144
phenyl
Me
H
F
CN
F
H
F
H
nonafluoro-2-butyl
H
CF3


2-3165
3-cyanophenyl
Me
H
F
CN
F
H
Cl
H
nonafluoro-2-butyl
H
CF3


2-3166
4-cyanophenyl
Me
H
F
CN
F
H
Cl
H
nonafluoro-2-butyl
H
CF3


2-3181
2-chloropyridin-3-yl
Me
H
F
CN
F
H
Cl
H
nonafluoro-2-butyl
H
CF3


2-3223
phenyl
Me
H
F
CN
F
H
Br
H
heptafluoroisopropyl
H
CF3


2-3243
3-cyanophenyl
Me
H
F
CN
F
H
Br
H
heptafluoroisopropyl
H
CF3


2-3244
4-cyanophenyl
Me
H
F
CN
F
H
Br
H
heptafluoroisopropyl
H
CF3


2-3259
2-chloropyridin-3-yl
Me
H
F
CN
F
H
Br
H
heptafluoroisopropyl
H
CF3


2-3301
phenyl
Me
H
F
CN
F
H
Br
H
nonafluoro-2-butyl
H
CF3


2-3321
3-cyanophenyl
Me
H
F
CN
F
H
Br
H
nonafluoro-2-butyl
H
CF3


2-3322
4-cyanophenyl
Me
H
F
CN
F
H
Br
H
nonafluoro-2-butyl
H
CF3


2-3337
2-chloropyridin-3-yl
Me
H
F
CN
F
H
Br
H
nonafluoro-2-butyl
H
CF3


2-3379
phenyl
Me
H
F
CN
F
H
I
H
heptafluoroisopropyl
H
CF3


2-3399
3-cyanophenyl
Me
H
F
CN
F
H
I
H
heptafluoroisopropyl
H
CF3


2-3400
4-cyanophenyl
Me
H
F
CN
F
H
I
H
heptafluoroisopropyl
H
CF3


2-3415
2-chloropyridin-3-yl
Me
H
F
CN
F
H
I
H
heptafluoroisopropyl
H
CF3


2-3457
phenyl
Me
H
F
CN
F
H
I
H
nonafluoro-2-butyl
H
CF3


2-3477
3-cyanophenyl
Me
H
F
CN
F
H
I
H
nonafluoro-2-butyl
H
CF3


2-3478
4-cyanophenyl
Me
H
F
CN
F
H
I
H
nonafluoro-2-butyl
H
CF3


2-3493
2-chloropyridin-3-yl
Me
H
F
CN
F
H
I
H
nonafluoro-2-butyl
H
CF3


2-3494
2-bromopyridin-3-yl
Me
H
F
CN
F
H
I
H
nonafluoro-2-butyl
H
CF3


2-3535
phenyl
Me
H
F
CN
F
H
OCF3
H
heptafluoroisopropyl
H
OCF3


2-3566
2-chloropyridin-3-yl
Me
H
F
CN
F
H
OCF3
H
heptafluoroisopropyl
H
OCF3


2-3591
phenyl
Me
H
F
CN
F
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


2-3622
2-chloropyridin-3-yl
Me
H
F
CN
F
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


2-3647
phenyl
Me
H
F
CN
F
H
CF3
H
heptafluoroisopropyl
H
OCF3


2-3678
2-chloropyridin-3-yl
Me
H
F
CN
F
H
CF3
H
heptafluoroisopropyl
H
OCF3


2-3703
phenyl
Me
H
F
CN
F
H
CF3
H
nonafluoro-2-butyl
H
OCF3


2-3734
2-chloropyridin-3-yl
Me
H
F
Cil
F
H
CF3
H
nonafluoro-2-butyl
H
OCF3


2-3759
phenyl
Me
H
F
CN
F
H
CF3
H
heptafluoroisopropyl
H
CF3


2-3779
3-cyanophenyl
Me
H
F
CN
F
H
CF3
H
heptafluoroisopropyl
H
CF3


2-3780
4-cyanophenyl
Me
H
F
CN
F
H
CF3
H
heptafluoroisopropyl
H
CF3


2-3795
2-chloropyridin-3-yl
Me
H
F
CN
F
H
CF3
H
heptafluoroisopropyl
H
CF3


2-3827
phenyl
Me
H
F
CN
F
H
CF3
H
nonafluoro-2-butyl
H
CF3


2-3847
3-cyanophenyl
Me
H
F
CN
F
H
CF3
H
nonafluoro-2-butyl
H
CF3


2-3848
4-cyanophenyl
Me
H
F
CN
F
H
CF3
H
nonafluoro-2-butyl
H
CF3


2-3863
2-chloropyridin-3-yl
Me
H
F
CN
F
H
CF3
H
nonafluoro-2-butyl
H
CF3











embedded image





















TABLE 3





compound














number
Q1
R1
R2
X1
X2
X3
X4
Y1
Y2
Y3
Y4
Y5







3-1
phenyl
H
Me
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


3-21
3-cyanophenyl
H
Me
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


3-22
4-cyanophenyl
H
Me
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


3-37
2-chloropyridin-3-yl
H
Me
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


3-79
phenyl
H
Me
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


3-99
3-cyanophenyl
H
Me
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


3-100
4-cyanophenyl
H
Me
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


3-115
2-chloropyridin-3-yl
H
Me
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


3-157
phenyl
H
Me
H
CN
H
H
Br
H
heptafluoroisopropyl
H
OCF3


3-177
3-cyanophenyl
H
Me
H
CN
H
H
Br
H
heptafluoroisopropyl
H
OCF3


3-178
4-cyanophenyl
H
Me
H
CN
H
H
Br
H
heptafluoroisopropyl
H
OCF3


3-193
2-chloropyridin-3-yl
H
Me
H
CN
H
H
Br
H
heptafluoroisopropyl
H
OCF3


3-235
phenyl
H
Me
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


3-255
3-cyanophenyl
H
Me
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


3-256
4-cyanophenyl
H
Me
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


3-271
2-chloropyridin-3-yl
H
Me
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


3-313
phenyl
H
Me
H
CN
H
H
I
H
heptafluoroisopropyl
H
OCF3


3-333
3-cyanophenyl
H
Me
H
CN
H
H
I
H
heptafluoroisopropyl
H
OCF3


3-334
4-cyanophenyl
H
Me
H
CN
H
H
I
H
heptafluoroisopropyl
H
OC2F5


3-349
2-chloropyridin-3-yl
H
Me
H
CN
H
H
I
H
heptafluoroisopropyl
H
OCF3


3-391
phenyl
H
Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
OCF3


3-411
3-cyanophenyl
H
Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
OCF3


3-412
4-cyanophenyl
H
Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
OCF3


3-427
2-chloropyridin-3-yl
H
Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
OCF3


3-469
phenyl
H
Me
H
CN
H
H
F
H
heptafluoroisopropyl
H
CF3


3-470
phenyl
H
Me
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


3-484
(3-trifluoromethyl) phenyl
H
Et
H
CN
H
H
Cl
H
pentafluoroethyl
H
CF3


3-490
3-cyanophenyl
H
Me
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


3-491
4-cyanophenyl
H
Me
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


3-495
2-chloro-4-fluorophenyl
H
n-Pr
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
C2F5


3-506
2-chloropyridin-3-yl
H
Me
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


3-512
6-fluoropyridin-3-yl
H
i-Pr
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


3-528
4-bromopyridin-3-yl
H
CH2CH═CH2
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


3-535
pyridin-4-yl
H
CN
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


3-548
phenyl
H
Me
H
CN
H
H
F
H
nonafiuoro-2-butyl
H
CF3


3-549
phenyl
H
Me
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


3-556
2-bromophenyl
H
CH2C≡CH
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


3-563
(3-trifluoromethyl) phenyl
H
NH2
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


3-569
3-cyanophenyl
H
Me
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


3-570
4-cyanophenyl
H
Me
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


3-576
4-bromo-2-chlorophenyl
H
C(O)OMe
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


3-585
2-chloropyridin-3-yl
H
Me
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


3-596
6-nitropyridin-3-yl
H
C(O)OEt
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


3-607
4-bromopyridin-3-yl
H
C(O)C(O)Me
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


3-610
4-nitropyridin-3-yl
H
C(O)C(O)Et
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


3-623
4-bromopyridin-2-yl
H
C(O)Me
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


3-625
6-chloropyridin-2-yl
H
C(O)Et
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


3-627
phenyl
H
Me
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


3-641
(3-trifluoromethyl) phenyl
H
S(O)2Me
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


3-647
3-cyanophenyl
H
Me
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


3-648
4-cyanophenyl
H
Me
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


3-659
4-cyano-2-fluorophenyl
H
S(O)2Et
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


3-663
2-chloropyridin-3-yl
H
Me
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


3-674
6-nitropyridin-3-yl
H
CH2Ph
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


3-688
4-nitropyridin-3-yl
H
CH2(3-Py)
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


3-702
5-iodopyridin-2-yl
H
CH2(3-Py—N-
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3





oxide)











3-705
phenyl
H
Me
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


3-725
3-cyanophenyl
H
Me
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


3-726
4-cyanophenyl
H
Me
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


3-732
4-bromo-2-chlorophenyl
H
Et
H
CN
H
H
Br
H
nonafluoro-2-buty1
H
CF3


3-741
2-chloropyridin-3-yl
H
Me
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


3-758
5-(trifluoromethyl) pyridin-3-yl
H
CN
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


3-783
phenyl
H
Me
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


3-803
3-cyanophenyl
H
Me
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


3-804
4-cyanophenyl
H
Me
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


3-819
2-chloropyridin-3-yl
H
Me
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


3-841
4-bromopyridin-3-yl
H
C(O)Me
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


3-861
phenyl
H
Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


3-881
3-cyanophenyl
H
Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


3-882
4-cyanophenyl
H
Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


3-897
2-chloropyridin-3-yl
H
Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


3-939
phenyl
H
Me
H
CN
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


3-970
2-chloropyridin-3-yl
H
Me
H
CN
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


3-995
phenyl
H
Me
H
CN
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


3-1026
2-chloropyridin-3-yl
H
Me
H
CN
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


3-1051
phenyl
H
Me
H
CN
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


3-1082
2-chloropyridin-3-yl
H
Me
H
CN
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


3-1107
phenyl
H
Me
H
CN
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


3-1138
2-chloropyridin-3-yl
H
Me
H
CN
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


3-1163
phenyl
H
Me
H
CN
H
H
CF3
H
heptafluoroisopropyl
H
CF3


3-1183
3-cyanophenyl
H
Me
H
CN
H
H
CF3
H
heptafluoroisopropyl
H
CF3


3-1184
4-cyanophenyl
H
Me
H
CN
H
H
CF3
H
heptafluoroisopropyl
H
CF3


3-1199
2-chloropyridin-3-yl
H
Me
H
CN
H
H
CF3
H
heptafluoroisopropyl
H
CF3


3-1231
phenyl
H
Me
H
CN
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


3-1251
3-cyanophenyl
H
Me
H
CN
H
H
CF3
H
nonafluoro-2-butyl
H
C2F5


3-1252
4-cyanophenyl
H
Me
H
CN
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


3-1267
2-chloropyridin-3-yl
H
Me
H
CN
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


3-1299
phenyl
H
Me
F
CN
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


3-1319
3-cyanophenyl
H
Me
F
CN
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


3-1320
4-cyanophenyl
H
Me
F
CN
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


3-1335
2-chloropyridin-3-yl
H
Me
F
CN
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


3-1377
phenyl
H
Me
F
CN
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


3-1397
3-cyanophenyl
H
Me
F
CN
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


3-1398
4-cyanophenyl
H
Me
F
CN
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


3-1413
2-chloropyridin-3-yl
H
Me
F
CN
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


3-1455
phenyl
H
Me
F
CN
H
H
Br
H
heptafluoroisopropyl
H
OCF3


3-1491
2-chloropyridin-3-yl
H
Me
F
CN
H
H
Br
H
heptafluoroisopropyl
H
OCF3


3-1533
phenyl
H
Me
F
CN
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


3-1553
3-cyanophenyl
H
Me
F
CN
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


3-1554
4-cyanophenyl
H
Me
F
CN
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


3-1569
2-chloropyridin-3-yl
H
Me
F
CN
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


3-1611
phenyl
H
Me
F
CN
H
H
I
H
heptafluoroisopropyl
H
OCF3


3-1631
3-cyanophenyl
H
Me
F
CN
H
H
I
H
heptafluoroisopropyl
H
OCF3


3-1632
4-cyanophenyl
H
Me
F
CN
H
H
I
H
heptafluoroisopropyl
H
OCF3


3-1647
2-chloropyridin-3-yl
H
Me
F
CN
H
H
I
H
heptafluoroisopropyl
H
OCF3


3-1689
phenyl
H
Me
F
CN
H
H
I
H
nonafluoro-2-butyl
H
OCF3


3-1709
3-cyanophenyl
H
Me
F
CN
H
H
I
H
nonafluoro-2-butyl
H
OCF3


3-1710
4-cyanophenyl
H
Me
F
CN
H
H
I
H
nonafluoro-2-butyl
H
OCF3


3-1725
2-chloropyridin-3-yl
H
Me
F
CN
H
H
I
H
nonafluoro-2-butyl
H
OCF3


3-1767
phenyl
H
Me
F
CN
H
H
F
H
heptafluoroisopropyl
H
CF3


3-1768
phenyl
H
Me
F
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


3-1788
3-cyanophenyl
H
Me
F
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


3-1789
4-cyanophenyl
H
Me
F
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


3-1804
2-chloropyridin-3-yl
H
Me
F
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


3-1846
phenyl
H
Me
F
CN
H
H
F
H
nonafluoro-2-butyl
H
CF3


3-1847
phenyl
H
Me
F
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


3-1867
3-cyanophenyl
H
Me
F
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


3-1868
4-cyanophenyl
H
Me
F
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


3-1883
2-chloropyridin-3-yl
H
Me
F
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


3-1925
phenyl
H
Me
F
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


3-1945
3-cyanophenyl
H
Me
F
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


3-1946
4-cyanophenyl
H
Me
F
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


3-1961
2-chloropyridin-3-yl
H
Me
F
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


3-2003
phenyl
H
Me
F
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


3-2023
3-cyanophenyl
H
Me
F
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


3-2024
4-cyanophenyl
H
Me
F
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


3-2039
2-chloropyridin-3-yl
H
Me
F
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


3-2081
phenyl
H
Me
F
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


3-2101
3-cyanophenyl
H
Me
F
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


3-2102
4-cyanophenyl
H
Me
F
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


3-2117
2-chloropyridin-3-yl
H
Me
F
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


3-2159
phenyl
H
Me
F
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


3-2179
3-cyanophenyl
H
Me
F
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


3-2180
4-cyanophenyl
H
Me
F
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


3-2195
2-chloropyridin-3-yl
H
Me
F
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


3-2237
phenyl
H
Me
F
CN
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


3-2268
2-chloropyridin-3-yl
H
Me
F
CN
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


3-2293
phenyl
H
Me
F
CN
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


3-2324
2-chloropyridin-3-yl
H
Me
F
CN
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


3-2349
phenyl
H
Me
F
CN
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


3-2380
2-chloropyridin-3-yl
H
Me
F
CN
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


3-2405
phenyl
H
Me
F
CN
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


3-2436
2-chloropyridin-3-yl
H
Me
F
CN
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


3-2461
phenyl
H
Me
F
CN
H
H
CF3
H
heptafluoroisopropyl
H
CF3


3-2481
3-cyanophenyl
H
Me
F
CN
H
H
CF3
H
heptafluoroisopropyl
H
CF3


3-2482
4-cyanophenyl
H
Me
F
CN
H
H
CF3
H
heptafluoroisopropyl
H
CF3


3-2497
2-chloropyridin-3-yl
H
Me
F
CN
H
H
CF3
H
heptafluoroisopropyl
H
CF3


3-2529
phenyl
H
Me
F
CN
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


3-2549
3-cyanophenyl
H
Me
F
CN
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


3-2550
4-cyanophenyl
H
Me
F
CN
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


3-2565
2-chloropyridin-3-yl
H
Me
F
CN
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


3-2597
phenyl
H
Me
F
CN
F
H
Cl
H
heptafluoroisopropyl
H
OCF3


3-2617
3-cyanophenyl
H
Me
F
CN
F
H
Cl
H
heptafluoroisopropyl
H
OCF3


3-2618
4-cyanophenyl
H
Me
F
CN
F
H
Cl
H
heptafluoroisopropyl
H
OCF3


3-2633
2-chloropyridin-3-yl
H
Me
F
CN
F
H
Cl
H
heptafluoroisopropyl
H
OCF3


3-2675
phenyl
H
Me
F
CN
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


3-2695
3-cyanophenyl
H
Me
F
CN
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


3-2696
4-cyanophenyl
H
Me
F
CN
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


3-2711
2-chloropyridin-3-yl
H
Me
F
CN
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


3-2753
phenyl
H
Me
F
CN
F
H
Br
H
heptafluoroisopropyl
H
OCF3


3-2773
3-cyanophenyl
H
Me
F
CN
F
H
Br
H
heptafluoroisopropyl
H
OCF3


3-2774
4-cyanophenyl
H
Me
F
CN
F
H
Br
H
heptafluoroisopropyl
H
OCF3


3-2789
2-chloropyridin-3-yl
H
Me
F
CN
F
H
Br
H
heptafluoroisopropyl
H
OCF3


3-2831
phenyl
H
Me
F
CN
F
H
Br
H
nonafluoro-2-butyl
H
OCF3


3-2851
3-cyanophenyl
H
Me
F
CN
F
H
Br
H
nonafluoro-2-butyl
H
OCF3


3-2852
4-cyanophenyl
H
Me
F
CN
F
H
Br
H
nonafluoro-2-butyl
H
OCF3


3-2867
2-chloropyridin-3-yl
H
Me
F
CN
F
H
Br
H
nonafluoro-2-butyl
H
OCF3


3-2909
phenyl
H
Me
F
CN
F
H
I
H
heptafluoroisopropyl
H
OCF3


3-2929
3-cyanophenyl
H
Me
F
CN
F
H
I
H
heptafluoroisopropyl
H
OCF3


3-2930
4-cyanophenyl
H
Me
F
CN
F
H
I
H
heptafluoroisopropyl
H
OCF3


3-2945
2-chloropyridin-3-yl
H
Me
F
CN
F
H
I
H
heptafluoroisopropyl
H
OCF3


3-2987
phenyl
H
Me
F
CN
F
H
I
H
nonafluoro-2-butyl
H
OCF3


3-2988
2-flurophenyl
H
Me
F
CN
F
H
I
H
nonafluoro-2-butyl
H
OCF3


3-3007
3-cyanophenyl
H
Me
F
CN
F
H
I
H
nonafluoro-2-butyl
H
OCF3


3-3008
4-cyanophenyl
H
Me
F
CN
F
H
I
H
nonafluoro-2-butyl
H
OCF3


3-3023
2-chloropyridin-3-yl
H
Me
F
CN
F
H
I
H
nonafluoro-2-butyl
H
OCF3


3-3065
phenyl
H
Me
F
CN
F
H
F
H
heptafluoroisopropyl
H
CF3


3-3066
phenyl
H
Me
F
CN
F
H
Cl
H
heptafluoroisopropyl
H
CF3


3-3086
3-cyanophenyl
H
Me
F
CN
F
H
Cl
H
heptafluoroisopropyl
H
CF3


3-3087
4-cyanophenyl
H
Me
F
CN
F
H
Cl
H
heptafluoroisopropyl
H
CF3


3-3102
2-chloropyridin-3-yl
H
Me
F
CN
F
H
Cl
H
heptafluoroisopropyl
H
CF3


3-3144
phenyl
H
Me
F
CN
F
H
F
H
nonafluoro-2-butyl
H
CF3


3-3145
phenyl
H
Me
F
CN
F
H
Cl
H
nonafluoro-2-butyl
H
CF3


3-3165
3-cyanophenyl
H
Me
F
CN
F
H
Cl
H
nonafluoro-2-butyl
H
CF3


3-3166
4-cyanophenyl
H
Me
F
CN
F
H
Cl
H
nonafluoro-2-butyl
H
CF3


3-3181
2-chloropyridin-3-yl
H
Me
F
CN
F
H
Cl
H
nonafluoro-2-butyl
H
CF3


3-3223
phenyl
H
Me
F
CN
F
H
Br
H
heptafluoroisopropyl
H
CF3


3-3243
3-cyanophenyl
H
Me
F
CN
F
H
Br
H
heptafluoroisopropyl
H
CF3


3-3244
4-cyanophenyl
H
Me
F
CN
F
H
Br
H
heptafluoroisopropyl
H
CF3


3-3259
2-chloropyridin-3-yl
H
Me
F
CN
F
H
Br
H
heptafluoroisopropyl
H
CF3


3-3301
phenyl
H
Me
F
CN
F
H
Br
H
nonafluoro-2-butyl
H
CF3


3-3321
3-cyanophenyl
H
Me
F
CN
F
H
Br
H
nonafluoro-2-butyl
H
CF3


3-3322
4-cyanophenyl
H
Me
F
CN
F
H
Br
H
nonafluoro-2-butyl
H
CF3


3-3337
2-chloropyridin-3-yl
H
Me
F
CN
F
H
Br
H
nonafluoro-2-butyl
H
CF3


3-3379
phenyl
H
Me
F
CN
F
H
I
H
heptafluoroisopropyl
H
CF3


3-3399
3-cyanophenyl
H
Me
F
CN
F
H
I
H
heptafluoroisopropyl
H
CF3


3-3400
4-cyanophenyl
H
Me
F
CN
F
H
I
H
heptafluoroisopropyl
H
CF3


3-3415
2-chloropyridin-3-yl
H
Me
F
CN
F
H
I
H
heptafluoroisopropyl
H
CF3


3-3457
phenyl
H
Me
F
CN
F
H
I
H
nonafluoro-2-butyl
H
CF3


3-3477
3-cyanophenyl
H
Me
F
CN
F
H
I
H
nonafluoro-2-butyl
H
CF3


3-3478
4-cyanophenyl
H
Me
F
CN
F
H
I
H
nonafluoro-2-butyl
H
CF3


3-3493
2-chloropyridin-3-yl
H
Me
F
CN
F
H
I
H
nonafluoro-2-butyl
H
CF3


3-3535
phenyl
H
Me
F
CN
F
H
OCF3
H
heptafluoroisopropyl
H
OCF3


3-3566
2-chloropyridin-3-yl
H
Me
F
CN
F
H
OCF3
H
heptafluoroisopropyl
H
OCF3


3-3591
phenyl
H
Me
F
CN
F
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


3-3622
2-chloropyridin-3-yl
H
Me
F
CN
F
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


3-3647
phenyl
H
Me
F
CN
F
H
CF3
H
heptafluoroisopropyl
H
OCF3


3-3678
2-chloropyridin-3-yl
H
Me
F
CN
F
H
CF3
H
heptafluoroisopropyl
H
OCF3


3-3703
phenyl
H
Me
F
CN
F
H
CF3
H
nonafluoro-2-butyl
H
OCF3


3-3734
2-chloropyridin-3-yl
H
Me
F
CN
F
H
CF3
H
nonafluoro-2-butyl
H
OCF3


3-3759
phenyl
H
Me
F
CN
F
H
CF3
H
heptafluoroisopropyl
H
CF3


3-3779
3-cyanophenyl
H
Me
F
CN
F
H
CF3
H
heptafluoroisopropyl
H
CF3


3-3780
4-cyanophenyl
H
Me
F
CN
F
H
CF3
H
heptafluoroisopropyl
H
CF3


3-3795
2-chloropyridin-3-yl
H
Me
F
CN
F
H
CF3
H
heptafluoroisopropyl
H
CF3











embedded image





















TABLE 4





compound














number
Q1
R1
R2
X1
X2
X3
X4
Y1
Y2
Y3
Y4
Y5







4-1
phenyl
Me
Me
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


4-21
3-cyanophenyl
Me
Me
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


4-22
4-cyanophenyl
Me
Me
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


4-37
2-chloropyridin-3-yl
Me
Me
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


4-79
phenyl
Me
Me
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


4-99
3-cyanophenyl
Me
Me
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


4-100
4-cyanophenyl
Me
Me
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


4-115
2-chloropyridin-3-yl
Me
Me
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


4-157
phenyl
Me
Me
H
CN
H
H
Br
H
heptafluoroisopropyl
H
OCF3


4-177
3-cyanophenyl
Me
Me
H
CN
H
H
Br
H
heptafluoroisopropyl
H
OCF3


4-178
4-cyanophenyl
Me
Me
H
CN
H
H
Br
H
heptafluoroisopropyl
H
OCF3


4-193
2-chloropyridin-3-yl
Me
Me
H
CN
H
H
Br
H
heptafluoroisopropyl
H
OCF3


4-235
phenyl
Me
Me
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


4-255
3-cyanophenyl
Me
Me
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


4-256
4-cyanophenyl
Me
Me
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


4-271
2-chloropyridin-3-yl
Me
Me
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


4-313
phenyl
Me
Me
H
CN
H
H
I
H
heptafluoroisopropyl
H
OCF3


4-314
2-fluorophenyl
Me
Me
H
CN
H
H
I
H
heptafluoroisopropyl
H
OOF3


4-333
3-cyanophenyl
Me
Me
H
CN
H
H
I
H
heptafluoroisopropyl
H
OCF3


4-334
4-cyanophenyl
Me
Me
H
CN
H
H
I
H
heptafluoroisopropyl
H
OCF3


4-349
2-chloropyridin-3-yl
Me
Me
H
CN
H
H
I
H
heptaftuoroisopropyl
H
OCF3


4-391
phenyl
Me
Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
OCF3


4-392
2-fluorophenyl
Me
Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
OCF3


4-411
3-cyanophenyl
Me
Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
OCF3


4-412
4-cyanophenyl
Me
Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
OCF3


4-427
2-chloropyridin-3-yl
Me
Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
OCF3


4-665
phenyl
Me
Me
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


4-666
(3-trifluoromethyl) phenyl
Et
Me
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


4-667
(4-trifluoromethyl) phenyl
Me
Et
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


4-671
2-cyanophenyl
Me
Me
H
CN
H
H
Cl
H
pentafluoroethyl
H
C2F5


4-672
3-cyanophenyl
Me
Me
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


4-673
4-cyanophenyl
Me
Me
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


4-676
2,4-dichlorophenyl
Me
Me
H
CN
H
H
Cl
H
heptafluorosopropyl
H
C2F5


4-677
2-chloro-4-fluorophenyl
n-Pr
Me
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


4-680
2-bromo-4-chlorophenyl
Me
Me
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


4-681
2-bromo-4-fluorophenyl
Me
n-Pr
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


4-687
2-fluoropyridin-3-yl
Me
Me
H
CN
H
H
Cl
H
pentafluoroethyl
H
CF3


4-688
2-chloropyridin-3-yl
Me
Me
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


4-692
2-nitropyridin-3-yl
Me
i-Pr
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


4-694
6-fluoropyridin-3-yl
i-Pr
Me
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


4-701
5-fluoropyridin-3-yl
Me
Me
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
C2F5


4-703
5-bromopyridin-3-yl
Me
Me
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


4-704
5-iodopyridin-3-yl
Me
Me
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
i-C3F7


4-706
5-nitropyridin-3-yl
Me
CH2CH═CH2
H
CN
H
H
Cl
H
pentafluoroethyl
H
CF3


4-708
5-fluoropyridin-3-yl
Me
Me
H
CN
H
H
Cl
H
pentafluoroethyl
H
CF3


4-710
4-bromopyridin-3-yl
CH2CH═CH2
Me
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


4-711
4-iodopyridin-3-yl
Me
Me
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
i-C3F7


4-717
pyridin-4-yl
CN
Me
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


4-724
pyridin-2-yl
Me
CN
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


4-729
4-cyanopyridin-2-yl
Me
Me
H
CN
H
H
Cl
H
pentafluoroethyl
H
CF3


4-730
phenyl
Me
Me
H
CN
H
H
F
H
nonafluoro-2-butyl
H
CF3


4-731
phenyl
Me
Me
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


4-732
2-fluorophenyl
Me
Me
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


4-739
3-bromophenyl
CH2C≡CH
Me
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


4-744
(2-trifluoromethyl) phenyl
Me
Me
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


4-745
(3-trifluoromethyl) phenyl
Me
CH2C≡CH
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


4-746
(4-trifluoromethyl) phenyl
NH2
Me
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


4-750
2-cyanophenyl
Me
NH2
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


4-751
3-cyanophenyl
Me
Me
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


4-752
4-cyanophenyl
Me
Me
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


4-759
2-bromo-4-chlorophenyl
C(O)OMe
Me
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


4-761
2-chloro-4-nitrophenyl
Me
C(O)OMe
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


4-767
2-chloropyridin-3-yl
Me
Me
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


4-773
6-fluoropyridin-3-yl
Me
C(O)OEt
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


4-780
5-fluoropyridin-3-yl
C(O)OEt
Me
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


4-781
5-chloropyridin-3-yl
Me
Me
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


4-782
5-bromopyridin-3-yl
Me
Me
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
n-C3F7


4-783
5-iodopyridin-3-yl
Me
Me
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
i-C357


4-785
5-nitropyridin-3-yl
Me
C(O)C(O)Me
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


4-787
4-fluoropyridin-3-yl
Me
Me
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


4-789
4-bromopyridin-3-yl
C(O)C(O)Me
Me
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


4-790
4-iodopyridin-3-yl
Me
C(O)C(O)Et
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


4-791
4-(trifluoromethyl) pyridin-3-yl
Me
Me
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
n-C3F7


4-792
4-nitropyridin-3-yl
C(O)C(O)Et
Me
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


4-803
pyridin-2-yl
Me
C(O)Me
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


4-805
4-bromopyridin-2-yl
Me
C(O)Et
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


4-806
5-iodopyridin-2-yl
C(O)Me
Me
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


4-808
4-cyanopyridin-2-yl
C(O)Et
Me
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


4-809
phenyl
Me
Me
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


4-823
(3-trifluoromethyl) phenyl
S(O)2Me
Me
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


4-828
2-cyanophenyl
Me
S(O)2Me
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


4-829
3-cyanophenyl
Me
Me
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


4-830
4-cyanophenyl
Me
Me
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


4-839
2-chloro-4-nitrophenyl
Me
S(O)2Et
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


4-841
4-cyano-2-fluorophenyl
S(O)2Et
Me
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


4-845
2-chloropyridin-3-yl
Me
Me
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


4-853
6-bromopyridin-3-yl
Me
CH2Ph
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


4-855
6-(trifluoromethyl) pyridin-3-yl
Me
Me
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


4-856
6-nitropyridin-3-yl
CH2Ph
Me
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


4-863
5-nitropyridin-3-yl
Me
CH2(3-Py)
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


4-865
4-fluoropyridin-3-yl
CH2(3-Py)
Me
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


4-883
4-bromopyridin-2-yl
Me
CH2(3-Py—N-
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3





oxide)











4-886
4-cyanopyridin-2-yl
CH2(3-Py—N-
Me
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3




oxide)












4-887
phenyl
Me
Me
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


4-907
3-cyanophenyl
Me
Me
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


4-908
4-cyanophenyl
Me
Me
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


4-923
2-chloropyridin-3-yl
Me
Me
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


4-965
phenyl
Me
Me
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


4-985
3-cyanophenyl
Me
Me
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


4-986
4-cyanophenyl
Me
Me
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


4-1001
2-chloropyridin-3-yl
Me
Me
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


4-1043
phenyl
Me
Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1063
3-cyanophenyl
Me
Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1064
4-cyanophenyl
Me
Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1079
2-chloropyridin-3-yl
Me
Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1121
phenyl
Et
Et
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1122
phenyl
Et
n-Pr
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1123
phenyl
Et
i-Pr
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1124
phenyl
Et
CH2CH═CH2
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1125
phenyl
Et
CN
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1126
phenyl
Et
CH2C≡CH
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1127
phenyl
Et
NH2
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1128
phenyl
Et
C(O)OMe
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1129
phenyl
Et
C(O)C(O)OMe
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1130
phenyl
Et
C(O)Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1131
phenyl
Et
S(O)2Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1132
phenyl
Et
CH2Ph
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1133
phenyl
Et
CH2(3-Py)
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1134
phenyl
Et
CH2(3-Py—N-
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3





oxide)











4-1135
phenyl
n-Pr
Et
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1136
phenyl
n-Pr
n-Pr
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1137
phenyl
n-Pr
i-Pr
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1138
phenyl
n-Pr
CH2CH═CH2
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1139
phenyl
n-Pr
CN
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1140
phenyl
n-Pr
CH2C≡OH
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1141
phenyl
n-Pr
NH2
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1142
phenyl
n-Pr
C(O)OMe
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1143
phenyl
n-Pr
C(O)C(O)OMe
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1144
phenyl
n-Pr
C(O)Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1145
phenyl
n-Pr
S(O)2Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1146
phenyl
n-Pr
CH2Ph
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1147
phenyl
n-Pr
CH2(3-Py)
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1148
phenyl
n-Pr
CH2(3-Py—N-
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3





oxide)











4-1149
phenyl
i-Pr
Et
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1150
phenyl
i-Pr
n-Pr
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1151
phenyl
i-Pr
i-Pr
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1152
phenyl
i-Pr
CH2CH═CH2
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1153
phenyl
i-Pr
CN
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1154
phenyl
i-Pr
CH2C≡CH
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1155
phenyl
i-Pr
NH2
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1156
phenyl
i-Pr
C(O)OMe
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1157
phenyl
i-Pr
C(O)C(O)OMe
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1158
phenyl
i-Pr
C(O)Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1159
phenyl
i-Pr
S(O)2Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1160
phenyl
i-Pr
CH2Ph
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1161
phenyl
i-Pr
CH2(3-Py)
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1162
phenyl
i-Pr
CH2(3-Py—N-
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3





oxide)











4-1163
phenyl
CH2CH═CH2
Et
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1164
phenyl
CH2CH═CH2
n-Pr
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1165
phenyl
CH2CH═CH2
i-Pr
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1166
phenyl
CH2CH═CH2
CH2CH═CH2
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1167
phenyl
CH2CH═CH2
CN
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1168
phenyl
CH2CH═CH2
CH2C≡CH
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1169
phenyl
CH2CH═CH2
NH2
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1170
phenyl
CH2CH═CH2
C(O)OMe
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1171
phenyl
CH2CH═CH2
C(O)C(O)OMe
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1172
phenyl
CH2CH═CH2
C(O)Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1173
phenyl
CH2CH═CH2
S(O)2Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1174
phenyl
CH2CH═CH2
CH2Ph
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1175
phenyl
CH2CH═CH2
CH2(3-Py)
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1176
phenyl
CH2CH═CH2
CH2(3-Py—N-
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3





oxide)











4-1177
phenyl
CN
Et
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1178
phenyl
CN
n-Pr
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1179
phenyl
CN
i-Pr
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1180
phenyl
CN
CH2CH═CH2
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1181
phenyl
CN
CN
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1182
phenyl
CN
CH2C≡CH
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1183
phenyl
CN
NH2
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1184
phenyl
CN
C(O)OMe
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1185
phenyl
CN
C(O)C(O)OMe
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1186
phenyl
CN
C(O)Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1187
phenyl
CN
S(O)2Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1188
phenyl
CN
CH2Ph
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1189
phenyl
CN
CH2(3-Py)
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1190
phenyl
CN
CH2(3-Py—N-
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3





oxide)











4-1191
phenyl
CH2C≡CH
Et
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1192
phenyl
CH2C≡CH
n-Pr
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1193
phenyl
CH2C≡CH
i-Pr
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1194
phenyl
CH2C≡CH
CH2CH═CH2
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1195
phenyl
CH2C≡CH
CN
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1196
phenyl
CH2C≡CH
CH2C≡CH
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1197
phenyl
CH2C≡CH
NH2
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1198
phenyl
CH2C≡CH
C(O)OMe
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1199
phenyl
CH2C≡CH
C(O)C(O)OMe
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1200
phenyl
CH2C≡CH
C(O)Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1201
phenyl
CH2C≡CH
S(O)2Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1202
phenyl
CH2C≡CH
CH2Ph
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1203
phenyl
CH2C≡CH
CH2(3-Py)
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1204
phenyl
CH2C≡CH
CH2(3-Py—N-
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3





oxide)











4-1205
phenyl
NH2
Et
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1206
phenyl
NH2
n-Pr
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1207
phenyl
NH2
i-Pr
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1208
phenyl
NH2
CH2CH═CH2
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1209
phenyl
NH2
CN
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1210
phenyl
NH2
CH2C≡CH
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1211
phenyl
NH2
NH2
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1212
phenyl
NH2
C(O)OMe
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1213
phenyl
NH2
C(O)C(O)OMe
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1214
phenyl
NH2
C(O)Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1215
phenyl
NH2
S(O)2Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1216
phenyl
NH2
CH2Ph
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1217
phenyl
NH2
CH2(3-Py)
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1218
phenyl
NH2
CH2(3-Py—N-
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3





oxide)











4-1219
phenyl
C(O)OMe
Et
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1220
phenyl
C(O)OMe
n-Pr
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1221
phenyl
C(O)OMe
i-Pr
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1222
phenyl
C(O)OMe
CH2CH═CH2
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1223
phenyl
C(O)OMe
CN
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1224
phenyl
C(O)OMe
CH2C≡CH
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1225
phenyl
C(O)OMe
NH2
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1226
phenyl
C(O)OMe
C(O)OMe
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1227
phenyl
C(O)OMe
C(O)C(O)OMe
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1228
phenyl
C(O)OMe
C(O)Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1229
phenyl
C(O)OMe
S(O)2Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1230
phenyl
C(O)OMe
CH2Ph
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1231
phenyl
C(O)OMe
CH2(3-Py)
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1232
phenyl
C(O)OMe
CH2(3-Py—N-
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3





oxide)











4-1233
phenyl
C(O)C(O)OMe
Et
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1234
phenyl
C(O)C(O)OMe
n-Pr
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1235
phenyl
C(O)C(O)OMe
i-Pr
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1236
phenyl
C(O)C(O)OMe
CH2CH═CH2
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1237
phenyl
C(O)C(O)OMe
CN
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1238
phenyl
C(O)C(O)OMe
CH2C≡CH
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1239
phenyl
C(O)C(O)OMe
NH2
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1240
phenyl
C(O)C(O)OMe
C(O)OMe
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1241
phenyl
C(O)C(O)OMe
C(O)C(O)OMe
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1242
phenyl
C(O)C(O)OMe
C(O)Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1243
phenyl
C(O)C(O)OMe
S(O)2Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1244
phenyl
C(O)C(O)OMe
CH2Ph
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1245
phenyl
C(O)C(O)OMe
CH2(3-Py)
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1246
phenyl
C(O)C(O)OMe
CH2(3-Py—N-
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3





oxide)











4-1247
phenyl
C(O)Me
Et
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1248
phenyl
C(O)Me
n-Pr
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1249
phenyl
C(O)Me
i-Pr
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1250
phenyl
C(O)Me
CH2CH═CH2
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1251
phenyl
C(O)Me
CN
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1252
phenyl
C(O)Me
CH2C≡CH
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1253
phenyl
C(O)Me
NH2
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1254
phenyl
C(O)Me
C(O)OMe
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1255
phenyl
C(O)Me
C(O)C(O)OMe
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1256
phenyl
C(O)Me
C(O)Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1257
phenyl
C(O)Me
S(O)2Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1258
phenyl
C(O)Me
CH2Ph
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1259
phenyl
C(O)Me
CH2(3-Py)
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1260
phenyl
C(O)Me
CH2(3-Py—N-
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3





oxide)











4-1261
phenyl
S(O)2Me
Et
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1262
phenyl
S(O)2Me
n-Pr
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1263
phenyl
S(O)2Me
i-Pr
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1264
phenyl
S(O)2Me
CH2CH═CH2
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1265
phenyl
S(O)2Me
CN
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1266
phenyl
S(O)2Me
CH2C≡CH
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1267
phenyl
S(O)2Me
NH2
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1268
phenyl
S(O)2Me
C(O)OMe
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1269
phenyl
S(O)2Me
C(O)C(O)OMe
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1270
phenyl
S(O)2Me
C(O)Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1271
phenyl
S(O)2Me
S(O)2Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1272
phenyl
S(O)2Me
CH2Ph
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1273
phenyl
S(O)2Me
CH2(3-Py)
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1274
phenyl
S(O)2Me
CH2(3-Py—N-
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3





oxide)











4-1275
phenyl
CH2Ph
Et
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1276
phenyl
CH2Ph
n-Pr
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1277
phenyl
CH2Ph
i-Pr
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1278
phenyl
CH2Ph
CH2CH═CH2
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1279
phenyl
CH2Ph
CN
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1280
phenyl
CH2Ph
CH2C≡CH
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1281
phenyl
CH2Ph
NH2
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1282
phenyl
CH2Ph
C(O)OMe
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1283
phenyl
CH2Ph
C(O)C(O)OMe
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1284
phenyl
CH2Ph
C(O)Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1285
phenyl
CH2Ph
S(O)2Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1286
phenyl
CH2Ph
CH2Ph
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1287
phenyl
CH2Ph
CH2(3-Py)
H
CN
H
H
I
H
nonaftuoro-2-butyl
H
CF3


4-1288
phenyl
CH2Ph
CH2(3-Py—N
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3





oxide)











4-1289
phenyl
CH2(3-Py)
Et
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1290
phenyl
CH2(3-Py)
n-Pr
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1291
phenyl
CH2(3-Py)
i-Pr
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1292
phenyl
CH2(3-Py)
CH2CH═CH2
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1293
phenyl
CH2(3-Py)
CN
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1294
phenyl
CH2(3-Py)
CH2C≡CH
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1295
phenyl
CH2(3-Py)
NH2
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1296
phenyl
CH2(3-Py)
C(O)OMe
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1297
phenyl
CH2(3-Py)
C(O)C(O)OMe
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1298
phenyl
CH2(3-Py)
C(O)Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1299
phenyl
CH2(3-Py)
S(O)2Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1300
phenyl
CH2(3-Py)
CH2Ph
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1301
phenyl
CH2(3-Py)
CH2(3-Py)
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-1302
phenyl
CH2(3-Py)
CH2(3-Py—N-
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3





oxide)











4-1303
phenyl
CH2(3-Py—N-
Et
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3




oxide)












4-1304
phenyl
CH2(3-Py—N-
n-Pr
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3




oxide)












4-1305
phenyl
CH2(3-Py—N-
i-Pr
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3




oxide)












4-1306
phenyl
CH2(3-Py—N-
CH2CH═CH2
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3




oxide)












4-1307
phenyl
CH2(3-Py—N-
CN
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3




oxide)












4-1308
phenyl
CH2(3-Py—N-
CH2C≡CH
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3




oxide)












4-1309
phenyl
CH2(3-Py—N-
NH2
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3




oxide)












4-1310
phenyl
CH2(3-Py—N-
C(O)OMe
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3




oxide)












4-1311
phenyl
CH2(3-Py—N-
C(O)C(O)OMe
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3




oxide)












4-1312
phenyl
CH2(3-Py—N-
C(O)Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3




oxide)












4-1313
phenyl
CH2(3-Py—N-
S(O)2Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3




oxide)












4-1314
phenyl
CH2(3-Py—N-
CH2Ph
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3




oxide)












4-1315
phenyl
CH2(3-Py—N-
CH2(3-Py)
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3




oxide)












4-1316
phenyl
CH2(3-Py—N-
CH2(3-Py—N-
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3




oxide)
oxide)











4-1317
phenyl
Me
Me
H
CN
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


4-1348
2-chloropyridin-3-yl
Me
Me
H
CN
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


4-1373
phenyl
Me
Me
H
CN
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


4-1404
2-chloropyridin-3-yl
Me
Me
H
CN
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


4-1429
phenyl
Me
Me
H
CN
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


4-1460
2-chloropyridin-3-yl
Me
Me
H
CN
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


4-1485
phenyl
Me
Me
H
CN
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


4-1516
2-chloropyridin-3-yl
Me
Me
H
CN
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


4-1541
phenyl
Me
Me
H
CN
H
H
CF3
H
heptafluoroisopropyl
H
CF3


4-1561
3-cyanophenyl
Me
Me
H
CN
H
H
CF3
H
heptafluoroisopropyl
H
CF3


4-1562
4-cyanophenyl
Me
Me
H
CN
H
H
CF3
H
heptafluoroisopropyl
H
CF3


4-1577
2-chloropyridin-3-yl
Me
Me
H
CN
H
H
CF3
H
heptafluoroisopropyl
H
CF3


4-1609
phenyl
Me
Me
H
CN
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


4-1629
3-cyanophenyl
Me
Me
H
CN
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


4-1630
4-cyanophenyl
Me
Me
H
CN
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


4-1645
2-chloropyridin-3-yl
Me
Me
H
CN
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


4-1873
phenyl
Me
Me
F
CN
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


4-1893
3-cyanophenyl
Me
Me
F
CN
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


4-1909
2-chloropyridin-3-yl
Me
Me
F
CN
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


4-1951
phenyl
Me
Me
F
CN
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


4-1971
3-cyanophenyl
Me
Me
F
CN
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


4-1972
4-cyanophenyl
Me
Me
F
CN
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


4-1987
2-chloropyridin-3-yl
Me
Me
F
CN
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


4-2029
phenyl
Me
Me
F
CN
H
H
Br
H
heptafluoroisopropyl
H
OCF3


4-2049
3-cyanophenyl
Me
Me
F
CN
H
H
Br
H
heptafluoroisopropyl
H
OCF3


4-2050
4-cyanophenyl
Me
Me
F
CN
H
H
Br
H
heptafluoroisopropyl
H
OCF3


4-2065
2-chloropyridin-3-yl
Me
Me
F
CN
H
H
Br
H
heptafluoroisopropyl
H
OCF3


4-2107
phenyl
Me
Me
F
CN
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


4-2127
3-cyanophenyl
Me
Me
F
CN
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


4-2128
4-cyanophenyl
Me
Me
F
CN
H
H
Br
H
nonafluoro-2-buty1
H
OCF3


4-2143
2-chloropyridin-3-yl
Me
Me
F
CN
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


4-2185
phenyl
Me
Me
F
CN
H
H
I
H
heptafluoroisopropyl
H
OCF3


4-2205
3-cyanophenyl
Me
Me
F
CN
H
H
I
H
heptafluoroisopropyl
H
OCF3


4-2206
4-cyanophenyl
Me
Me
F
CN
H
H
I
H
heptafluoroisopropyl
H
OCF3


4-2221
2-chloropyridin-3-yl
Me
Me
F
CN
H
H
I
H
heptafluoroisopropyl
H
OCF3


4-2263
phenyl
Me
Me
F
CN
H
H
I
H
nonafluoro-2-butyl
H
OCF3


4-2283
3-cyanophenyl
Me
Me
F
CN
H
H
I
H
nonafluoro-2-butyl
H
OCF3


4-2284
4-cyanophenyl
Me
Me
F
CN
H
H
I
H
nonafluoro-2-butyl
H
OCF3


4-2299
2-chloropyridin-3-yl
Me
Me
F
CN
H
H
I
H
nonafluoro-2-butyl
H
OCF3


4-2537
phenyl
Me
Me
F
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


4-2538
phenyl
Et
Me
F
CN
H
H
F
H
heptafluoroisopropyl
H
CF3


4-2544
3-cyanophenyl
Me
Me
F
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


4-2545
4-cyanophenyl
Me
Me
F
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


4-2560
2-chloropyridin-3-yl
Me
Me
F
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


4-2602
phenyl
Me
Me
F
CN
H
H
F
H
nonafluoro-2-butyl
H
CF3


4-2603
phenyl
Me
Me
F
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


4-2623
3-cyanophenyl
Me
Me
F
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


4-2624
4-cyanophenyl
Me
Me
F
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


4-2639
2-chloropyridin-3-yl
Me
Me
F
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


4-2681
phenyl
Me
Me
F
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


4-2701
3-cyanophenyl
Me
Me
F
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


4-2702
4-cyanophenyl
Me
Me
F
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


4-2717
2-chloropyridin-3-yl
Me
Me
F
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


4-2759
phenyl
Me
Me
F
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


4-2779
3-cyanophenyl
Me
Me
F
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


4-2780
4-cyanophenyl
Me
Me
F
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


4-2795
2-chloropyridin-3-yl
Me
Me
F
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


4-2837
phenyl
Me
Me
F
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


4-2857
3-cyanophenyl
Me
Me
F
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


4-2858
4-cyanophenyl
Me
Me
F
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


4-2873
2-chloropyridin-3-yl
Me
Me
F
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


4-2915
phenyl
Me
Me
F
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-2935
3-cyanophenyl
Me
Me
F
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-2936
4-cyanophenyl
Me
Me
F
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-2951
2-chloropyridin-3-yl
Me
Me
F
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


4-3189
phenyl
Me
Me
F
CN
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


4-3220
2-chloropyridin-3-yl
Me
Me
F
CN
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


4-3245
phenyl
Me
Me
F
CN
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


4-3276
2-chloropyridin-3-yl
Me
Me
F
CN
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


4-3301
phenyl
Me
Me
F
CN
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


4-3332
2-chloropyridin-3-yl
Me
Me
F
CN
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


4-3357
phenyl
Me
Me
F
CN
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


4-3388
2-chloropyridin-3-yl
Me
Me
F
CN
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


4-3413
phenyl
Me
Me
F
CN
H
H
CF3
H
heptafluoroisopropyl
H
CF3


4-3433
3-cyanophenyl
Me
Me
F
CN
H
H
CF3
H
heptafluoroisopropyl
H
CF3


4-3434
4-cyanophenyl
Me
Me
F
CN
H
H
CF3
H
heptafluoroisopropyl
H
CF3


4-3449
2-chloropyridin-3-yl
Me
Me
F
CN
H
H
CF3
H
heptafluoroisopropyl
H
CF3


4-3481
phenyl
Me
Me
F
CN
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


4-3493
4-iodophenyl
Me
Me
F
CN
H
H
C2F5
H
nonafluoro-2-butyl
H
CF3


4-3501
3-cyanophenyl
Me
Me
F
CN
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


4-3502
4-cyanophenyl
Me
Me
F
CN
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


4-3517
2-chloropyridin-3-yl
Me
Me
F
CN
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


4-3745
phenyl
Me
Me
F
CN
F
H
Cl
H
heptafluoroisopropyl
H
OCF3


4-3765
3-cyanophenyl
Me
Me
F
CN
F
H
Cl
H
heptafluoroisopropyl
H
OCF3


4-3766
4-cyanophenyl
Me
Me
F
CN
F
H
Cl
H
heptafluoroisopropyl
H
OCF3


4-3781
2-chloropyridin-3-yl
Me
Me
F
CN
F
H
Cl
H
heptafluoroisopropyl
H
OCF3


4-3823
phenyl
Me
Me
F
CN
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


4-3843
3-cyanophenyl
Me
Me
F
CN
F
H
Cl
H
nonafluoro-2-butyl
FI
OCF3


4-3844
4-cyanophenyl
Me
Me
F
CN
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


4-3859
2-chloropyridin-3-yl
Me
Me
F
CN
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


4-3901
phenyl
Me
Me
F
CN
F
H
Br
H
heptafluoroisopropyl
H
OCF3


4-3921
3-cyanophenyl
Me
Me
F
CN
F
H
Br
H
heptafluoroisopropyl
H
OCF3


4-3922
4-cyanophenyl
Me
Me
F
CN
F
H
Br
H
heptafluoroisopropyl
H
OCF3


4-3937
2-chloropyridin-3-yl
Me
Me
F
CN
F
H
Br
H
heptafluoroisopropyl
H
OCF3


4-3979
phenyl
Me
Me
F
CN
F
H
Br
H
nonafluoro-2-butyl
H
OCF3


4-3999
3-cyanophenyl
Me
Me
F
CN
F
H
Br
H
nonafluoro-2-butyl
H
OCF3


4-4000
4-cyanophenyl
Me
Me
F
CN
F
H
Br
H
nonafluoro-2-butyl
H
OCF3


4-4015
2-chloropyridin-3-yl
Me
Me
F
CN
F
H
Br
H
nonafluoro-2-butyl
H
OCF3


4-4057
phenyl
Me
Me
F
CN
F
H
I
H
heptafluoroisopropyl
H
OCF3


4-4077
3-cyanophenyl
Me
Me
F
CN
F
H
I
H
heptafluoroisopropyl
H
OCF3


4-4078
4-cyanophenyl
Me
Me
F
CN
F
H
I
H
heptafluoroisopropyl
H
OCF3


4-4093
2-chloropyridin-3-y1
Me
Me
F
CN
F
H
I
H
heptafluoroisopropyl
H
OCF3


4-4135
phenyl
Me
Me
F
CN
F
H
I
H
nonafluoro-2-butyl
H
OCF3


4-4155
3-cyanophenyl
Me
Me
F
CN
F
H
I
H
nonafluoro-2-butyl
H
OCF3


4-4156
4-cyanophenyl
Me
Me
F
CN
F
H
I
H
nonafluoro-2-butyl
H
OCF3


4-4171
2-chloropyridin-3-yl
Me
Me
F
CN
F
H
I
H
nonafluoro-2-butyl
H
OCF3


4-4409
phenyl
Me
Me
F
CN
F
H
Cl
H
heptafluoroisopropyl
H
CF3


4-4410
phenyl
Et
Me
F
CN
F
H
F
H
heptafluoroisopropyl
H
CF3


4-4416
3-cyanophenyl
Me
Me
F
CN
F
H
Cl
H
heptafluoroisopropyl
H
CF3


4-4417
4-cyanophenyl
Me
Me
F
CN
F
H
Cl
H
heptafluoroisopropyl
H
CF3


4-4432
2-chloropyridin-3-yl
Me
Me
F
CN
F
H
Cl
H
heptafluoroisopropyl
H
CF3


4-4474
phenyl
Me
Me
F
CN
F
H
F
H
nonafluoro-2-butyl
H
CF3


4-4475
phenyl
Me
Me
F
CN
F
H
Cl
H
nonafluoro-2-butyl
H
CF3


4-4495
3-cyanophenyl
Me
Me
F
CN
F
H
Cl
H
nonafluoro-2-butyl
H
CF3


4-4496
4-cyanophenyl
Me
Me
F
CN
F
H
Cl
H
nonafluoro-2-butyl
H
CF3


4-4511
2-chloropyridin-3-yl
Me
Me
F
CN
F
H
Cl
H
nonafluoro-2-butyl
H
CF3


4-4553
phenyl
Me
Me
F
CN
F
H
Br
H
heptafluoroisopropyl
H
CF3


4-4573
3-cyanophenyl
Me
Me
F
CN
F
H
Br
H
heptafluoroisopropyl
H
CF3


4-4574
4-cyanophenyl
Me
Me
F
CN
F
H
Br
H
heptafluoroisopropyl
H
CF3


4-4589
2-chloropyridin-3-yl
Me
Me
F
CN
F
H
Br
H
heptafluoroisopropyl
H
CF3


4-4631
phenyl
Me
Me
F
CN
F
H
Br
H
nonafluoro-2-butyl
H
CF3


4-4651
3-cyanophenyl
Me
Me
F
CN
F
H
Br
H
nonafluoro-2-butyl
H
CF3


4-4652
4-cyanophenyl
Me
Me
F
CN
F
H
Br
H
nonafluoro-2-butyl
H
CF3


4-4667
2-chloropyridin-3-yl
Me
Me
F
CN
F
H
Br
H
nonafluoro-2-butyl
H
CF3


4-4709
phenyl
Me
Me
F
CN
F
H
I
H
heptafluoroisopropyl
H
CF3


4-4729
3-cyanophenyl
Me
Me
F
CN
F
H
I
H
heptafluoroisopropyl
H
CF3


4-4730
4-cyanophenyl
Me
Me
F
CN
F
H
I
H
heptafluoroisopropyl
H
CF3


4-4745
2-chloropyridin-3-yl
Me
Me
F
CN
F
H
I
H
heptafluoroisopropyl
H
CF3


4-4787
phenyl
Me
Me
F
CN
F
H
I
H
nonafluoro-2-butyl
H
CF3


4-4807
3-cyanophenyl
Me
Me
F
CN
F
H
I
H
nonafluoro-2-butyl
H
CF3


4-4808
4-cyanophenyl
Me
Me
F
CN
F
H
I
H
nonafluoro-2-butyl
H
CF3


4-4823
2-chloropyridin-3-yl
Me
Me
F
CN
F
H
I
H
nonafluoro-2-butyl
H
CF3


4-5061
phenyl
Me
Me
F
CN
F
H
OCF3
H
heptafluoroisopropyl
H
OCF3


4-5092
2-chloropyridin-3-yl
Me
Me
F
CN
F
H
OCF3
H
heptafluoroisopropyl
H
OCF3


4-5117
phenyl
Me
Me
F
CN
F
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


4-5148
2-chloropyridin-3-yl
Me
Me
F
CN
F
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


4-5173
phenyl
Me
Me
F
CN
F
H
CF3
H
heptafluoroisopropyl
H
OCF3


4-5204
2-chloropyridin-3-yl
Me
Me
F
CN
F
H
CF3
H
heptafluoroisopropyl
H
OCF3


4-5229
phenyl
Me
Me
F
CN
F
H
CF3
H
nonafluoro-2-butyl
H
OCF3


4-5260
2-chloropyridin-3-yl
Me
Me
F
CN
F
H
CF3
H
nonafluoro-2-butyl
H
OCF3


4-5285
phenyl
Me
Me
F
CN
F
H
CF3
H
heptafluoroisopropyl
H
CF3


4-5305
3-cyanophenyl
Me
Me
F
CN
F
H
CF3
H
heptafluoroisopropyl
H
CF3


4-5306
4-cyanophenyl
Me
Me
F
CN
F
H
CF3
H
heptafluoroisopropyl
H
CF3


4-5321
2-chloropyridin-3-yl
Me
Me
F
CN
F
H
CF3
H
heptafluoroisopropyl
H
CF3


4-5353
phenyl
Me
Me
F
CN
F
H
CF3
H
nonafluoro-2-butyl
H
CF3


4-5373
3-cyanophenyl
Me
Me
F
CN
F
H
CF3
H
nonafluoro-2-butyl
H
CF3


4-5374
4-cyanophenyl
Me
Me
F
CN
F
H
CF3
H
nonafluoro-2-butyl
H
CF3


4-5389
2-chloropyridin-3-yl
Me
Me
F
CN
F
H
CF3
H
nonafluoro-2-butyl
H
CF3











embedded image





















TABLE 5





compound














number
Q1
R1
R2
X1
X2
X3
X4
Y1
Y2
Y3
Y4
Y5







5-9
3-bromophenyl
H
Et
H
CN
H
H
Cl
F
heptafluoroisopropyl
F
OCF3


5-39
2-iodopyridin-3-yl
H
H
H
CN
H
H
Cl
Me
nonafluoro-2-butyl
Me
OCF3


5-144
phenyl
H
H
H
CN
H
H
Cl
F
heptafluoroisopropyl
H
CF3


5-145
2-fluorophenyl
Me
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
F
CF3


5-146
3-fluorophenyl
H
Me
H
CN
H
H
Cl
Cl
heptafluoroisopropyl
H
CF3


5-147
4-fluorophenyl
Me
Me
H
CN
H
H
Cl
H
heptafluoroisopropyl
Cl
CF3


5-148
2-chlorophenyl
H
H
H
CN
H
H
F
Br
heptafluoroisopropyl
H
CF3


5-149
3-chlorophenyl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
Br
CF3


5-150
4-chlorophenyl
Et
H
H
CN
H
H
Cl
I
heptafluorolsopropyl
H
C2F5


5-151
2-bromophenyl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
I
CF3


5-152
3-bromophenyl
H
Et
H
CN
H
H
Cl
F
heptafluoroisopropyl
F
CF3


5-153
4-bromophenyl
H
H
H
CN
H
H
Cl
F
heptafluoroisopropyl
Cl
CF3


5-154
2-iodophenyl
H
H
H
CN
H
H
Cl
F
heptafluoroisopropyl
Br
CF3


5-155
3-iodophenyl
Et
Et
H
CN
H
H
Cl
F
pentafluoroethyl
I
C2F5


5-156
4-iodophenyl
H
H
H
CN
H
H
Cl
Cl
pentafluoroethyl
F
CF3


5-157
(2-trifluoromethyl) phenyl
H
H
H
CN
H
H
Cl
Cl
heptafluoroisopropyl
Cl
CF3


5-158
(3-fluoromethyl) phenyl
n-Pr
H
H
CN
H
H
Cl
Cl
heptafluoroisopropyl
Br
CF3


6-159
(4-trifluoromethyl) phenyl
H
H
H
CN
H
H
Cl
Cl
heptafluoroisopropyl
I
n-C3F7


5-160
2-nitrophenyl
H
n-Pr
H
CN
H
H
Cl
Br
heptafluoroisopropyl
F
CF3


5-161
3-nitrophenyl
H
H
H
CN
H
H
Cl
Br
heptafluoroisopropyl
Cl
CF3


5-162
4-nitrophenyl
H
H
H
CN
H
H
Cl
Br
heptafluoroisopropyl
Br
CF3


5-163
2-cyanophenyl
n-Pr
n-Pr
H
CN
H
H
Cl
Br
pentafluoroethyl
I
CF3


5-164
3-cyanophenyl
H
H
H
CN
H
H
F
I
nonefluoro-2-butyl
F
CF3


5-165
4-cyanophenyl
H
H
H
CN
H
H
Cl
I
nonafluoro-2-butyl
Cl
CF3


6-166
2,6-difluorophenyl
H
H
H
CN
H
H
Cl
I
nonafluoro-2-butyl
Br
CF3


5-167
3,4-dichlorophenyl
H
H
H
CN
H
H
Cl
I
nonafluoro-2-butyl
I
CF3


5-168
2,4-dichlorophenyl
H
H
H
CN
H
H
Cl
Me
nonafluoro-2-butyl
H
CF3


5-169
2-chloro-4-fluorophenyl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
Me
CF3


5-170
2-chloro-4,5-difluorophenyl
i-Pr
H
H
CN
H
H
Cl
Et
nonafluoro-2-butyl
H
CF3


5-171
4-bromo-2-chlorophenyl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
Et
CF3


5-172
2-bromo-4-chlorophenyl
H
H
H
CN
H
H
Cl
n-Pr
nonafluoro-2-butyl
H
CF3


5-173
2-bromo-4-fluorophenyl
H
i-Pr
H
CN
H
H
Cl
H
nonafluoro-2-butyl
n-Pr
CF3


5-174
2-chloro-4-nitrophened
i-Pr
i-Pr
H
CN
H
H
Cl
1-Pr
nonafluoro-2-butyl
H
CF3


5-175
3,5-dicyanophenyl
H
H
H
CN
H
H
Cl
H
nonefluoro-2-butyl
i-Pr
CF3


5-176
4-cyano-2-fluorophenyl
H
H
H
CN
H
H
Cl
n-Bu
nonafluoro-2-butyl
H
CF3


5-177
2-chloro-4-cyanophenyl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
n-Bu
CF3


5-178
pyridin-3-yl
H
H
H
CN
H
H
Cl
i-Bu
nonafluoro-2-butyl
H
CF3


5-179
2-fluoropyridin-3-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
i-Bu
CF3


5-180
2-chloropyridin-3-yl
H
H
H
CN
H
H
Cl
s-Bu
nonafluoro-2-butyl
H
C2F5


5-181
2-bromopyridin-3-yl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
s-Bu
CF3


5-182
2-iodopyridin-3-yl
H
H
H
CN
H
H
Cl
Me
nonafluoro-2-butyl
Me
n-C3F7


5-183
2-(trifluoromethyl) pyridin-3-yl
H
H
H
CN
H
H
Cl
Me
nonafluoro-2-butyl
Et
i-C3F7


5-184
2-nitropyridin-3-yl
C(O)Me
H
H
CN
H
H
Cl
Me
nonafluoro-2-butyl
n-Pr
CF3


5-185
2-cyanopyridin-3-yl
H
H
H
CN
H
H
Cl
Me
nonafluoro-2-butyl
i-Pr
CF3


5-186
6-fluoropyridin-3-yl
H
H
H
CN
H
H
Cl
Me
nonafluoro-2-butyl
n-Bu
CF3


5-187
6-chloropyridin-3-yl
H
H
H
CN
H
H
Cl
Me
nonafluoro-2-butyl
i-Bu
CF3


5-188
6-bromopyridin-3-yl
H
C(O)Me
H
CN
H
H
Cl
Me
nonafluoro-2-butyl
s-Bu
CF3


5-189
6-iodopyridin-3-yl
H
H
H
CN
H
H
Br
Et
nonafluoro-2-butyl
Me
n-C3F7


5-190
6-(trifluoromethyl)pyridin-3-yl
H
H
H
CN
H
H
Br
Et
nonafluoro-2-butyl
Et
i-C3F7


5-191
6-nitropyridin-3-yl
C(O)Me
C(O)Me
H
CN
H
H
Br
Et
nonafluoro-2-butyl
n-Pr
CF3


5-192
6-cyanopyridin-3-yl
H
H
H
CN
H
H
Br
Et
nonafluoro-2-butyl
i-Pr
CF3


5-193
phenyl
H
H
H
CN
H
H
Br
Et
heptafluoroisopropyl
n-Bu
CF3


5-194
5-fluoropyridin-3-yl
H
H
H
CN
H
H
Br
Et
heptafluoroisopropyl
i-Bu
CF3


5-195
5-chloropyridin-3-yl
H
H
H
CN
H
H
Br
Et
heptafluoroisopropyl
s-Bu
CF3


5-196
5-bromopyridin-3-yl
H
H
H
CN
H
H
Br
n-Pr
heptafluoroisopropyl
Me
CF3


5-197
5-iodopyridin-3-yl
H
H
H
CN
H
H
Br
n-Pr
heptafluoroisopropyl
Et
CF3


5-198
5-(trifluoromethyl) pyridin-3-yl
Me
Et
H
CN
H
H
Br
n-Pr
pentafluoroethyl
n-Pr
CF3


5-199
5-nitropyridin-3-yl
H
H
H
CN
H
H
Br
n-Pr
heptafluoroisopropyl
i-Pr
CF3


5-200
5-cyanopyridin-3-yl
H
H
H
CN
H
H
Br
n-Pr
pentafluoroethyl
n-Bu
CF3


5-201
4-fluoropyridin-3-yl
H
H
H
CN
H
H
Br
n-Pr
heptafluoroisopropyl
i-Bu
CF3


5-202
4-chloropyridin-3-yl
H
H
H
CN
H
H
Br
n-Pr
heptafluoroisopropyl
s-Bu
CF3


5-203
4-bromopyridin-3-yl
Me
n-Pr
H
CN
H
H
Br
i-Pr
heptafluoroisopropyl
Me
CF3


5-204
4-iodopyridin-3-yl
H
H
H
CN
H
H
Br
i-Pr
heptafluoroisopropyl
Et
CF3


5-205
4-(fluoromethyl) pyridin-3-yl
H
H
H
CN
H
H
Br
i-Pr
heptafluoroisopropyl
n-Pr
CF3


5-206
4-nitropyridin-3-yl
H
H
H
CN
H
H
Br
1-Pr
heptafluoroisopropyl
i-Pr
CF3


5-207
4-cyanopyridin-3-yl
H
H
H
CN
H
H
Br
i-Pr
heptafluoroisopropyl
n-Bu
CF3


5-208
2,6-dichloropyridin-3-yl
H
H
H
CN
H
H
Br
i-Pr
heptafluoroisopropyl
i-Bu
CF3


5-209
pyridin-3-yl N-oxide
Me
i-Pr
H
CN
H
H
Br
i-Pr
heptafluoroisopropyl
s-Bu
CF3


5-210
pyridin-4-yl
H
H
H
CN
H
H
Br
n-Bu
heptafluoroisopropyl
Me
CF3


5-211
2-chloropyridin-4-yl
H
H
H
CN
H
H
Br
n-Bu
heptafluoroisopropyl
Et
CF3


5-212
3-bromopyridin-4-yl
H
H
H
CN
H
H
Br
n-Bu
heptafluoroisopropyl
n-Pr
CF3


5-213
3,5-dichloropyridin-4-yl
H
H
H
CN
H
H
Br
n-Bu
nonafluoro-2-butyl
i-Pr
CF3


5-214
3-(trifluoromethyl) pyridin-4-yl
H
H
H
CN
H
H
Br
n-Bu
nonafluoro-2-butyl
n-Bu
CF3


5-215
2,6-dicyanopyridin-4-yl
H
H
H
CN
H
H
Br
n-Bu
nonafluoro-2-butyl
i-Bu
CF3


5-216
pyridin-4-yl N-oxide
Me
C(O)Me
H
CN
H
H
Br
n-Bu
nonafluoro-2-butyl
s-Bu
CF3


5-217
pyridin-2-yl
H
H
H
CN
H
H
Br
i-Bu
nonafluoro-2-butyl
Me
CF3


5-218
3-chloropyridin-2-yl
H
H
H
CN
H
H
Br
i-Bu
nonafluoro-2-butyl
Et
CF3


5-219
4-bromopyridin-2-yl
H
H
H
CN
H
H
Br
i-Bu
nonafluoro-2-butyl
i-Pr
CF3


5-220
5-iodopyridin-2-yl
H
H
H
CN
H
H
Br
i-Bu
nonafluoro-2-butyl
i-Pr
CF3


5-221
6-chloropyridin-2-yl
H
H
H
CN
H
H
Br
i-Bu
nonafluoro-2-butyl
n-Bu
CF3


5-222
4-cyanopyridin-2-yl
H
H
H
CN
H
H
Br
i-Bu
nonafluoro-2-butyl
i-Bu
CF3


5-223
phenyl
H
H
H
CN
H
H
Br
i-Bu
nonafluoro-2-butyl
s-Bu
C2F5


5-224
2-fluorophenyl
H
H
H
CN
H
H
Br
s-Bu
nonafluoro-2-butyl
Me
CF3


5-225
3-fluorophenyl
H
H
H
CN
H
H
Br
s-Bu
nonafluoro-2-butyl
Et
CF3


5-226
4-fluorophenyl
H
H
H
CN
H
H
Br
s-Bu
nonafluoro-2-butyl
n-Pr
CF3


5-227
2-ohlorophenyl
H
H
H
CN
H
H
Br
s-Bu
nonafluoro-2-butyl
i-Pr
CF3


5-228
3-chlorophenyl
H
H
H
CN
H
H
Br
s-Bu
nonafluoro-2-butyl
n-Bu
CF3


5-229
4-chlorophenyl
H
H
H
CN
H
H
Br
s-Bu
nonafluoro-2-butyl
i-Bu
CF3


5-230
2-bromophenyl
Et
Me
H
CN
H
H
Sr
s-Bu
nonafluoro-2-butyl
s-Bu
CF3


5-231
3-bromophenyl
H
H
H
CN
H
H
Br
F
nonafluoro-2-butyl
Me
CF3


5-232
4-bromophenyl
H
H
H
CN
H
H
Br
F
nonafluoro-2-butyl
Et
CF3


5-233
2-iodophenyl
H
H
H
CN
H
H
Br
F
nonafluoro-2-butyl
n-Pr
CF3


5-234
3-iodophenyl
H
H
H
CN
H
H
Br
F
nonafluoro-2-butyl
i-Pr
CF3


5-235
4-iodophenyl
H
H
H
CN
H
H
Br
F
nonafluoro-2-butyl
n-Bu
CF3


5-236
(2-trifluoromethyl) phenyl
H
H
H
CN
H
H
Br
F
nonafluoro-2-butyl
i-Bu
CF3


5-237
(3-trifluoromethyl) phenyl
Et
n-Pr
H
CN
H
H
Br
F
nonafluoro-2-butyl
s-Bu
CF3


5-238
(4-trifluoromethyl) phenyl
Et
i-Pr
H
CN
H
H
Br
Cl
nonafluoro-2-butyl
Me
CF3


5-239
2-nitrophenyl
H
H
H
CN
H
H
Br
Cl
nonafluoro-2-butyl
Et
CF3


5-240
phenyl
H
H
H
CN
H
H
I
Cl
pentafluoroethyl
n-Pr
i-C3F7


5-241
3-nitrophenyl
H
H
H
CN
H
H
I
Cl
heptafluoroisopropyl
i-Pr
CF3


5-242
4-nitrophenyl
H
H
H
CN
H
H
I
Cl
heptafluoroisopropyl
n-Bu
CF3


5-243
2-cyanophenyl
Et
C(O)Me
H
CN
H
H
I
Cl
heptafluoroisopropyl
i-Bu
CF3


5-244
3-cyanophenyl
H
H
H
CN
H
H
I
Cl
heptafluoroisopropyl
s-Bu
CF3


5-245
4-cyanophenyl
H
H
H
CN
H
H
I
Br
heptafluoroisopropyl
Me
CF3


5-246
2,6-difluorophenyl
H
H
H
CN
H
H
I
Br
heptafluoroisopropyl
Et
CF3


5-247
3,4-dichlorophenyl
H
H
H
CN
H
H
I
Br
pentafluoroethyl
n-Pr
CF3


5-248
2,4-dichlorophenyl
H
H
H
CN
H
H
I
Br
heptafluoroisopropyl
i-Pr
CF3


5-249
2-chloro-4-fluorophenyl
H
H
H
CN
H
H
I
Br
heptafluoroisopropyl
n-Bu
CF3


5-250
2-chloro-4,5-difluorophenyl
H
H
H
CN
H
H
I
Br
heptafluoroisopropyl
i-Bu
CF3


5-251
4-bromo-2-chlorophenyl
H
H
H
CN
H
H
I
Br
heptafluoroisopropyl
s-Bu
CF3


5-252
2-bromo-4-chlorophenyl
n-Pr
Me
H
CN
H
H
I
I
heptafluoroisopropyl
Me
CF3


5-253
2-bromo-4-fluorophenyl
H
H
H
CN
H
H
I
I
heptafluoroisopropyl
Et
CF3


5-254
2-chloro-4-nitrophenyl
n-Pr
Et
H
CN
H
H
I
I
heptafluoroisopropyl
n-Pr
CF3


5-255
3,5-dicyanophenyl
H
H
H
CN
H
H
I
I
heptafluoroisopropyl
i-Pr
CF3


5-256
4-cyano-2-fluorophenyl
H
H
H
CN
H
H
I
I
heptafluoroisopropyl
n-Bu
CF3


5-257
2-chloro-4-cyanophenyl
H
H
H
CN
H
H
I
I
heptafluoroisopropyl
i-Bu
CF3


5-258
pyridin-3-yl
H
H
H
CN
H
H
I
I
heptafluoroisopropyl
s-Bu
CF3


5-259
2-fluoropyridin-3-yl
H
H
H
CN
H
H
I
Me
heptafluoroisopropyl
F
C2F5


5-260
2-chloropyridin-3-yl
H
H
H
CN
H
H
I
Me
nonafluoro-2-butyl
Cl
CF3


5-261
2-bromopyridin-3-yl
H
H
H
CN
H
H
I
Me
nonafluoro-2-butyl
Br
n-C3F7


5-262
2-iodopyridin-3-yl
H
H
H
CN
H
H
I
Me
nonafluoro-2-butyl
I
i-C3F7


5-263
2-(trifluoromethyl) pyridin-3-yl
H
H
H
CN
H
H
I
Et
nonafluoro-2-butyl
F
CF3


5-264
2-nitropyridin-3-yl
H
H
H
CN
H
H
I
Et
nonafluoro-2-butyl
Cl
CF3


5-265
2-cyanopyridin-3-yl
H
H
H
CN
H
H
I
Et
nonafluoro-2-butyl
Br
CF3


5-266
6-fluoropyridin-3-yl
n-Pr
i-Pr
H
CN
H
H
I
Et
nonafluoro-2-butyl
I
C2F5


5-267
6-chloropyridin-3-yl
H
H
H
CN
H
H
I
n-Pr
nonafluoro-2-butyl
F
CF3


5-268
6-bromopyridin-3-yl
H
H
H
CN
H
H
I
n-Pr
nonafluoro-2-butyl
Cl
CF3


5-269
6-iodopyridin-3-yl
H
H
H
CN
H
H
I
n-Pr
nonafluoro-2-butyl
Br
CF3


5-270
6-(trifluoromethyl) pyridin-3-yl
H
H
H
CN
H
H
I
n-Pr
nonafluoro-2-butyl
I
n-C3F7


5-271
6-nitropyridin-3-yl
H
H
H
CN
H
H
I
i-Pr
nonafluoro-2-butyl
F
i-C3F7


5-272
6-cyanopyridin-3-yl
H
H
H
CN
H
H
I
i-Pr
nonafluoro-2-butyl
Cl
CF3


5-273
5-fluoropyridin-3-yl
n-Pr
C(O)Me
H
CN
H
H
I
i-Pr
nonafluoro-2-butyl
Br
CF3


5-274
5-chloropyridin-yl
H
H
H
CN
H
H
I
i-Pr
nonafluoro-2-butyl
I
CF3


5-275
5-bromopyridin-3-yl
H
H
H
CN
H
H
I
n-Bu
nonafluoro-2-butyl
F
CF3


5-276
5-iodopyridin-3-yl
H
H
H
CN
H
H
I
n-Bu
nonafluoro-2-butyl
Cl
CF3


5-277
5-(trifluoromethyl) pyridin-3-yl
H
H
H
CN
H
H
I
n-Bu
nonafluoro-2-butyl
Br
CF3


5-278
5-nitropyridin-3-yl
i-Pr
Me
H
CN
H
H
I
n-Bu
nonafluoro-2-butyl
I
CF3


5-279
5-cyanopyridin-3-yl
H
H
H
CN
H
H
I
i-Bu
nonafluoro-2-butyl
F
CF3


5-280
4-fluoropyridin-3-yl
H
H
H
CN
H
H
I
i-Bu
nonafluoro-2-butyl
Cl
CF3


5-281
4-chloropyridin-3-yl
H
H
H
CN
H
H
I
i-Bu
nonafluoro-2-butyl
Br
CF3


5-282
4-bromopyridin-3-yl
i-Pr
Et
H
CN
H
H
I
i-Bu
nonafluoro-2-butyl
I
CF3


5-283
4-iodopyridin-3-yl
i-Pr
n-Pr
H
CN
H
H
I
s-Bu
nonafluoro-2-butyl
F
CF3


5-284
4-(trifluoromethyl) pyridin-3-yl
H
H
H
CN
H
H
I
s-Bu
nonafluoro-2-butyl
Cl
CF3


5-285
4-nitropyridin-3-yl
i-Pr
C(O)Me
H
CN
H
H
I
s-Bu
nonafluoro-2-butyl
Br
CF3


5-286
4-cyanopyridin-3-yl
H
H
H
CN
H
H
I
s-Bu
nonafluoro-2-butyl
I
CF3


5-295
3-bromophenyl
H
Et
H
CN
H
H
OCF3
F
heptafluoroisopropyl
F
OCF3


5-325
2-iodopyridin-3-yl
H
H
H
CN
H
H
OCF3
Me
nonefluoro-2-butyl
Me
OCF3


5-438
3-bromophenyl
H
Et
H
CN
H
H
OCF3
F
heptafluoroisopropyl
F
CF3


5-468
2-iodopyridin-3-yl
H
H
H
CN
H
H
OCF3
Me
nonafluoro-2-butyl
Me
OF3


5-581
3-bromophenyl
H
Et
H
CN
H
H
CF3
F
heptafluoroisopropyl
F
CF3


5-611
2-iodopyridin-3-yl
H
H
H
CN
H
H
CF3
Me
nonafluoro-2-butyl
Me
CF3


5-724
3-bromophenyl
H
Et
F
CN
H
H
Cl
F
heptafluoroisopropyl
F
OCF3


5-754
2-iodopyridin-3-yl
H
H
F
CN
H
H
Cl
Me
nonafluoro-2-butyl
Me
OCF3


5-863
2-chlorophenyl
H
H
F
CN
H
H
F
Br
heptafluoroisopropyl
H
CF3


5-869
2-iodophenyl
H
H
F
CN
H
H
Cl
F
heptafluoroisopropyl
Br
CF3


5-876
3-nitrophenyl
H
H
F
CN
H
H
Cl
Br
heptafluoroisopropyl
Cl
CF3


5-883
2,4-dichlorophenyl
H
H
F
CN
H
H
Cl
Me
nonafluoro-2-butyl
H
CF3


5-884
2-chloro-4-fluorophenyl
H
H
F
CN
H
H
Cl
H
nonafluoro-2-butyl
Me
CF3


5-885
2-chloro-4,5-difluorophenyl
i-Pr
H
F
CN
H
H
Cl
Et
nonafluoro-2-butyl
H
CF3


5-886
4-bromo-2-chlorophenyl
H
H
F
CN
H
H
Cl
H
nonafluoro-2-butyl
Et
CF3


5-897
2-iodopyridin-3-yl
H
H
F
CN
H
H
Cl
Me
nonafluoro-2-butyl
Me
n-C3F7


5-898
2-(trifluoromethyl) pyridin-3-yl
H
H
F
CN
H
H
Cl
Me
nonafluoro-2-butyl
Et
i-C3F7


5-904
6-iodopyridin-3-yl
H
H
F
CN
H
H
Cl
Et
nonafluoro-2-butyl
Me
n-C3F7


5-905
6-(trifluoromethyl) pyridin-3-yl
H
H
F
CN
H
H
Cl
Et
nonafluoro-2-butyl
Et
i-C3F7


5-911
5-bromopyridin-3-yl
H
H
F
CN
H
H
Br
n-Pr
heptafluoroisopropyl
Me
CF3


5-912
5-iodopyridin-3-yl
H
H
F
CN
H
H
Br
n-Pr
heptafluoroisopropyl
Et
CF3


5-918
4-bromopyridin-3yl
Me
n-Pr
F
CN
H
H
Br
i-Pr
heptafluoroisopropyl
Me
CF3


5-919
4-iodopyridin-3-yl
H
H
F
CN
H
H
Br
i-Pr
heptafluoroisopropyl
Et
CF3


5-925
pyridin-4-yl
H
H
F
CN
H
H
Br
n-Bu
heptafluoroisopropyl
Me
CF3


5-926
2-chloropyridin-4-yl
H
H
F
CN
H
H
Br
n-Bu
heptafluoroisopropyl
Et
CF3


5-932
pyridin-2-yl
H
H
F
CN
H
H
Br
i-Bu
nonafluoro-2-butyl
Me
CF3


5-933
3-chloropyridin-2-yl
H
H
F
CN
H
H
Br
i-Bu
nonafluoro-2-butyl
Et
CF3


5-939
2-fluorophenyl
H
H
F
CN
H
H
Br
s-Bu
nonafluoro-2-butyl
Me
CF3


5-940
3-fluorophenyl
H
H
F
CN
H
H
Br
s-Bu
nonafluoro-2-butyl
Et
CF3


5-946
3-bromophenyl
H
H
F
CN
H
H
Br
F
nonafluoro-2-butyl
Me
CF3


5-947
4-bromophenyl
H
H
F
CN
H
H
Br
F
nonafluoro-2-butyl
Et
CF3


5-953
(4-trifluoromethyl) phenyl
Et
i-Pr
F
CN
H
H
Br
Cl
nonafluoro-2-butyl
Me
CF3


5-954
2-nitrophenyl
H
H
F
CN
H
H
Br
Cl
nonafluoro-2-butyl
Et
CF3


5-960
4-cyanophenyl
H
H
F
CN
H
H
I
Br
heptafluoroisopropyl
Me
CF3


5-961
2,6-difluorophenyl
H
H
F
CN
H
H
I
Br
heptafluoroisopropyl
Et
CF3


5-967
2-bromo-4-chlorophenyl
n-Pr
Me
F
CN
H
H
I
I
heptafluoroisopropyl
Me
CF3


5-968
2-bromo-4-fluorophenyl
H
H
F
CN
H
H
I
I
heptafluoroisopropyl
Et
CF3


5-974
2-fluoropyridin-3-yl
H
H
F
CN
H
H
I
Me
heptafluoroisopropyl
F
C2F5


5-975
2-chloropyridin-3-yl
H
H
F
CN
H
H
I
Me
nonafluoro-2-butyl
Cl
CF3


5-978
2-(trifluoromethyl) pyridin-3-yl
H
H
F
CN
H
H
I
Et
nonafluoro-2-butyl
F
CF3


5-979
2-nitropyridin-3-yl
H
H
F
CN
H
H
I
Et
nonafluoro-2-butyl
Cl
CF3


5-982
6-chloropyridin-3-yl
H
H
F
CN
H
H
I
n-Pr
nonafluoro-2-butyl
F
CF3


5-983
6-bromopyridin-3-yl
H
H
F
CN
H
H
I
n-Pr
nonafluoro-2-butyl
Cl
CF3


5-986
6-nitropyridin-3-yl
H
H
F
CN
H
H
I
i-Pr
nonafluoro-2-butyl
F
i-C3F7


5-987
6-cyanopyridin-3-yl
H
H
F
CN
H
H
I
i-Pr
nonafluoro-2-butyl
Cl
CF3


5-990
5-bromopyridin-3-yl
H
H
F
CN
H
H
I
n-Bu
nonafluoro-2-butyl
F
CF3


5-991
5-iodopyridin-3-yl
H
H
F
CN
H
H
I
n-Bu
nonafluoro-2-butyl
Cl
OF3


5-994
5-cyanopyridin-3-yl
H
H
F
CN
H
H
I
i-Bu
nonafluoro-2-butyl
F
CF3


5-995
4-fluoropyridin-3-yl
H
H
F
CN
H
H
I
i-Bu
nonafluoro-2-butyl
Cl
CF3


5-998
4-iodopyridin-3-yl
i-Pr
n-Pr
F
CN
H
H
I
s-Bu
nonafluoro-2-butyl
F
CF3


5-999
4-(trifluoromethyl) pyridin-3-yl
H
H
F
CN
H
H
I
s-Bu
nonafluoro-2-butyl
Cl
CF3


5-1010
3-bromophenyl
H
Et
F
CN
H
H
OCF3
F
heptafluoroisopropyl
F
OCF3


5-1040
2-iodopyridin-3-yl
H
H
F
CN
H
H
OCF3
Me
nonafluoro-2-butyl
Mn
OCF3


5-1153
3-bromophenyl
H
Et
F
CN
H
H
OCF3
F
heptatluoroisopropyl
F
CF3


5-1183
2-iodopyridin-3-yl
H
H
F
CN
H
H
OCF3
Mn
nonafluoro-2-butyl
Me
CF3


5-1296
3-bromophenyl
H
Et
F
CN
H
H
CF3
F
heptafluoroisopropyl
F
CF3


5-1326
2-iodopyridin-3-yl
H
H
F
CN
H
H
CF3
Mn
nonafluoro-2-butyl
Mn
CF3


5-1439
3-bromophenyl
H
Et
F
CN
F
H
Cl
F
heptafluoroisopropyl
F
OCF3


5-1469
2-iodopyridin-3-yl
H
H
F
CN
F
H
Cl
Mn
nonafluoro-2-butyl
Mn
OCF3


5-1576
3-fluorophenyl
H
Me
F
CN
F
H
Cl
Cl
heptafluoroisopropyl
H
CF3


5-1583
4-bromophenyl
H
H
F
CN
F
H
Cl
F
heptafluoroisopropyl
Cl
CF3


5-1591
3-nitrophenyl
H
H
F
CN
F
H
Cl
Br
heptafluoroisopropyl
Cl
CF3


5-1598
2,4-dichlorophonyl
H
H
F
CN
F
H
Cl
Me
nonafluoro-2-butyl
H
CF3


5-1599
2-chloro-4-fluorophenyl
H
H
F
CN
F
H
Cl
H
nonafluoro-2-butyl
Me
CF3


5-1600
2-chloro-4,5-difluorophenyl
i-Pr
H
F
CN
F
H
Cl
Et
nonafluoro-2-butyl
H
CF3


5-1601
4-bromo-2-chlorophenyl
H
H
F
CN
F
H
Cl
H
nonafluoro-2-butyl
Et
CF3


5-1612
2-iodopyridin-3-yl
H
H
F
CN
F
H
Cl
Mn
nonafluoro-2-butyl
Me
n-C3F7


5-1613
2-(trifluoromethyl) pyridin-3-yl
H
H
F
CN
F
H
Cl
Me
nonafluoro-2-butyl
Et
i-C3F7


5-1619
6-iodopyridin-3-yl
H
H
F
CN
F
H
Cl
Et
nonafluoro-2-butyl
Me
n-C3F7


5-1620
6-(trifluoromethyl) pyridin-3-yl
H
H
F
CN
F
H
Cl
Et
nonafluoro-2-butyl
Et
i-C3F7


5-1626
5-bromopyridin-3-yl
H
H
F
CN
F
H
Br
n-Pr
heptafluoroisopropyl
Me
CF3


5-1627
5-iodopyridin-3-yl
H
H
F
CN
F
H
Br
n-Pr
heptafluoroisopropyl
Et
CF3


5-1633
4-bromopyridin-3-yl
Me
n-Pr
F
CN
F
H
Br
i-Pr
heptafluoroisopropyl
Me
CF3


5-1634
4-iodopyridin-3-yl
H
H
F
CN
F
H
Br
i-Pr
heptafluoroisopropyl
Et
CF3


5-1640
pyridin-4-yl
H
H
F
CN
F
H
Br
n-Bu
heptafluoroisopropyl
Me
CF3


5-1641
2-chloropyridin-4-yl
H
H
F
CN
F
H
Br
n-Bu
heptafluoroisopropyl
Et
CF3


5-1647
pyridin-2-yl
H
H
F
CN
F
H
Br
i-Bu
nonafluoro-2-butyl
Me
CF3


5-1648
3-chloropyridin-2-yl
H
H
F
CN
F
H
Br
i-Bu
nonafluoro-2-butyl
Et
CF3


5-1654
2-fluorophenyl
H
H
F
CN
F
H
Br
s-Bu
nonafluoro-2-butyl
Me
CF3


5-1655
3-fluorophenyl
H
H
F
CN
F
H
Br
s-Bu
nonafluoro-2-butyl
Et
CF3


5-1661
3-bromophenyl
H
H
F
CN
F
H
Br
F
nonafluoro-2-butyl
Me
CF3


5-1662
4-bromophenyl
H
H
F
CN
F
H
Br
F
nonafluoro-2-butyl
Et
CF3


5-1668
(4-trifluoromethyl) phenyl
Et
i-Pr
F
CN
F
H
Br
Cl
nonafluoro-2-butyl
Me
CF3


5-1669
2-nitrophenyl
H
H
F
CN
F
H
Br
Cl
nonafluoro-2-butyl
Et
CF3


5-1675
4-cyanophenyl
H
H
F
CN
F
H
I
Br
heptafluoroisopropyl
Me
CF3


5-1676
2,6-difluorophenyl
H
H
F
CN
F
H
I
Br
heptafluoroisopropyl
Et
CF3


5-1682
2-bromo-4-chlorophenyl
n-Pr
Me
F
CN
F
H
I
I
heptafluoroisopropyl
Me
CF3


5-1683
2-bromo-4-fluorophenyl
H
H
F
CN
F
H
I
I
heptafluoroisopropyl
Et
CF3


5-1689
2-fluoropyridin-3-yl
H
H
F
CN
F
H
I
Me
heptafluoroisopropyl
F
C2F5


5-1690
2-chloropyridin-3-yl
H
H
F
CN
F
H
I
Me
nonafluoro-2-butyl
Cl
CF3


5-1693
2-(trifluoromethyl) pyridin-3-yl
H
H
F
CN
F
H
I
Et
nonafluoro-2-butyl
F
CF3


5-1694
2-nitropyridin-3-yl
H
H
F
CN
F
H
I
Et
nonafluoro-2-butyl
Cl
CF3


5-1697
6-chloropyridin-3-yl
H
H
F
CN
F
H
I
n-Pr
nonafluoro-2-butyl
F
CF3


5-1698
6-bromopyridin-3-yl
H
H
F
CN
F
H
I
n-Pr
nonafluoro-2-butyl
Cl
CF3


5-1701
6-nitropyridin-3-yl
H
H
F
CN
F
H
I
i-Pr
nonafluoro-2-butyl
F
i-C3F7


5-1702
6-cyanopyridin-3-yl
H
H
F
CN
F
H
I
i-Pr
nonafluoro-2-butyl
Cl
CF3


5-1705
5-bromopyridin-3-yl
H
H
F
CN
F
H
I
n-Bu
nonafluoro-2-butyl
F
CF3


5-1706
5-iodopyrdin-3-yl
H
H
F
CN
F
H
I
n-Bu
nonafluoro-2-butyl
Cl
CF3


5-1709
5-cyanopyridin-3-yl
H
H
F
CN
F
H
I
i-Bu
nonafluoro-2-butyl
F
CF3


5-1710
4-fluoropyridin-3-yl
H
H
F
CN
F
H
I
i-Bu
nonafluoro-2-butyl
Cl
CF3


5-1713
4-iodopyridin-3-yl
i-Pr
N-Pr
F
CN
F
H
I
s-Bu
nonafluoro-2-butyl
F
CF3


5-1714
4-(trifluoropmethyl) pyridin-3-yl
H
H
F
CN
F
H
I
s-Bu
nonafluoro-2-butyl
Cl
CF3


5-1725
3-bromophenyl
H
Et
F
CN
F
H
OCF3
F
heptafluoroisopropyl
F
OCF3


5-1755
2-iodopyridin-3-yl
H
H
F
CN
F
H
OCF3
Me
nonafluoro-2-butyl
Me
OCF3


5-1868
3-bromophenyl
H
Et
F
CN
F
H
OCF3
F
heptafluoroisopropyl
F
CF3


5-1898
2-iodopyridin-3-yl
H
H
F
CN
F
H
OCF3
Me
nonafluoro-2-butyl
Me
CF3


5-2011
3-bromophenyl
H
Et
F
CN
F
H
CF3
F
heptafluoroisopropyl
F
CF3


5-2041
2-iodopyridin-3-yl
H
H
F
CN
F
H
CF3
Me
nonafluoro-2-butyl
Me
CF3











embedded image





















TABLE 6





compound














number
Q1
R1
R2
X1
X2
X3
X4
Y1
Y2
Y3
Y4
Y5







6-1
phenyl
H
H
H
H
H
H
F
H
nonafluoro-2-butyl
H
F


6-2
3-cyanophenyl
H
H
H
H
H
H
F
H
nonafluoro-2-butyl
H
F


6-3
4-cyanophenyl
H
H
H
H
H
H
F
H
nonafluoro-2-butyl
H
F


6-4
2-chloropyridin-3-yl
H
H
H
H
H
H
F
H
nonafluoro-2-butyl
H
F


6-5
phenyl
H
H
H
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


6-12
3-cyanophenyl
H
H
H
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


6-13
4-cyanophenyl
H
H
H
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


6-24
2-chloropyridin-3-yl
H
H
H
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


6-38
phenyl
H
H
H
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


6-39
2-fluorophenyl
H
H
H
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


6-45
3-cyanophenyl
H
H
H
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


6-46
4-cyanophenyl
H
H
H
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


6-47
2,6-difluorophenyl
H
H
H
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


6-57
2-chloropyridin-3-yl
H
H
H
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


6-60
6-chloropyridin-3-yl
H
H
H
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


6-71
phenyl
H
H
H
H
H
H
I
H
nonafluoro-2-butyl
H
I


6-72
2-fluorophenyl
H
H
H
H
H
H
I
H
nonafluoro-2-butyl
H
I


6-78
3-cyanophenyl
H
H
H
H
H
H
I
H
nonafluoro-2-butyl
H
I


6-79
4-cyanophenyl
H
H
H
H
H
H
I
H
nonafluoro-2-butyl
H
I


6-80
2,6-difluorophenyl
H
H
H
H
H
H
I
H
nonafluoro-2-butyl
H
I


6-90
2-chloropyridin-3-yl
H
H
H
H
H
H
I
H
nonafluoro-2-butyl
H
I


6-93
6-chloropyridin-3-yl
H
H
H
H
H
H
1
H
nonafluoro-2-butyl
H
I


6-104
phenyl
H
H
H
H
H
H
F
H
nonafluoro-2-butyl
H
Cl


6-105
phenyl
H
H
H
H
H
H
F
H
nonafluoro-2-butyl
H
Br


6-106
phenyl
H
H
H
H
H
H
F
H
nonafluoro-2-butyl
H
I


6-107
phenyl
H
H
H
H
H
H
Cl
H
nonafluoro-2-butyl
H
Br


6-108
phenyl
H
H
H
H
H
H
Cl
H
nonafluoro-2-butyl
H
I


6-109
phenyl
H
H
H
H
H
H
Br
H
nonafluoro-2-butyl
H
I


6-110
phenyl
H
H
H
H
H
H
F
H
heptafluoroisopropyl
H
CF3


6-111
phenyl
H
H
H
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-131
3-cyanophenyl
H
H
H
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-132
4-cyanophenyl
H
H
H
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-147
2-chloropyridin-3-yl
H
H
H
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-189
phenyl
H
H
H
H
H
H
F
H
nonafluoro-2-butyl
H
CF3


6-190
phenyl
H
H
H
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


6-210
3-cyanophenyl
H
H
H
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


6-211
4-cyanophenyl
H
H
H
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


6-226
2-chloropyridin-3-yl
H
H
H
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


6-268
phenyl
H
H
H
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-269
2-fluorophenyl
H
H
H
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-270
3-fluorophenyl
H
H
H
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-271
4-fluorophenyl
H
H
H
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-272
2-chlorophenyl
H
H
H
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-288
3-cyanophenyl
H
H
H
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-289
4-cyanophenyl
H
H
H
H
H
H
.Br
H
heptafluoroisopropyl
H
CF3


6-290
2,6-difluorophenyl
H
H
H
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-293
2-chloro-4-fluorophenyl
H
H
H
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-300
4-cyano-2-fluorophenyl
H
H
H
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-304
2-chloropyridin-3-yl
H
H
H
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-305
2-bromopyridin-3-yl
H
H
H
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-306
2-iodopyridin-3-yl
H
H
H
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-311
6-chloropyridin-3-yl
H
H
H
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-346
phenyl
H
H
H
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-347
2-fluorophenyl
H
H
H
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-348
3-fluorophenyl
H
H
H
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-349
4-fluorophenyl
H
H
H
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-366
3-cyanophenyl
H
H
H
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-367
4-cyanophenyl
H
H
H
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-368
2,6-difluorophenyl
H
H
H
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-382
2-chloropyridin-3-yl
H
H
H
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-389
6-chloropyridin-3-yl
H
H
H
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-424
phenyl
H
H
H
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-425
2-fluorophenyl
H
H
H
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-426
3-fluorophenyl
H
H
H
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-427
4-fluorophenyl
H
H
H
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-428
2-chlorophenyl
H
H
H
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-444
3-cyanophenyl
H
H
H
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-445
4-cyanophenyl
H
H
H
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-446
2,6-difluorophenyl
H
H
H
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-448
2,4-dichlorophenyl
H
H
H
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-449
2-chloro-4-fluorophenyl
H
H
H
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-450
2-chloro-4,5-difluorophenyl
H
H
H
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-451
4-bromo-2-chlorophenyl
H
H
H
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-452
2-bromo-4-chlorophenyl
H
H
H
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-453
2-bromo-4-fluorophenyl
H
H
H
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-454
2-chloro-4-nitrophenyl
H
H
H
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-460
2-chloropyridin-3-yl
H
H
H
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-461
2-bromopyridin-3-yl
H
H
H
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-467
6-chloropyridin-3-yl
H
H
H
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-502
phenyl
H
H
H
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-503
2-fluorophenyl
H
H
H
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-504
3-fluorophenyl
H
H
H
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-505
4-fluorophenyl
H
H
H
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-522
3-cyanophenyl
H
H
H
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-523
4-cyanophenyl
H
H
H
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-524
2,6-difluorophenyl
H
H
H
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-538
2-chloropyridin-3-yl
H
H
H
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-545
6-chloropyridin-3-yl
H
H
H
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-580
phenyl
H
H
H
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


6-595
3-cyanophenyl
H
H
H
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


6-596
4-cyanophenyl
H
H
H
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


6-611
2-chloropyridin-3-yl
H
H
H
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


6-636
phenyl
H
H
H
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


6-651
3-cyanophenyl
H
H
H
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


6-652
4-cyanophenyl
H
H
H
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


6-667
2-chloropyridin-3-yl
H
H
H
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


6-692
phenyl
H
H
H
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


6-707
3-cyanophenyl
H
H
H
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


6-708
4-cyanophenyl
H
H
H
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


6-723
2-chloropyridin-3-yl
H
H
H
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


6-748
phenyl
H
H
H
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


6-763
3-cyanophenyl
H
H
H
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


6-764
4-cyanophenyl
H
H
H
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


6-779
2-chloropyridin-3-yl
H
H
H
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


6-804
phenyl
H
H
H
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


6-824
3-cyanophenyl
H
H
H
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


6-825
4-cyanophenyl
H
H
H
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


6-840
2-chloropyridin-3-yl
H
H
H
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


6-841
2-bromopyridin-3-yl
H
H
H
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


6-872
phenyl
H
H
H
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


6-892
3-cyanophenyl
H
H
H
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


6-893
4-cyanophenyl
H
H
H
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


6-908
2-chloropyridin-3-yl
H
H
H
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


6-940
phenyl
H
H
F
H
H
H
F
H
heptafluoroisopropyl
H
F


6-941
3-cyanophenyl
H
H
F
H
H
H
F
H
heptafluoroisopropyl
H
F


6-942
4-cyanophenyl
H
H
F
H
H
H
F
H
heptafluoroisopropyl
H
F


6-943
2-chloropyridin-3-yl
H
H
F
H
H
H
F
H
heptafluoroisopropyl
H
F


6-944
phenyl
H
H
F
H
H
H
F
H
nonafluoro-2-butyl
H
F


6-945
3-cyanophenyl
H
H
F
H
H
H
F
H
nonafluoro-2-butyl
H
F


6-946
4-cyanophenyl
H
H
F
H
H
H
F
H
nonafluoro-2-butyl
H
F


6-947
2-chloropyridin-3-yl
H
H
F
H
H
H
F
H
nonafluoro-2-butyl
H
F


6-948
phenyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


6-952
2-chlorophenyl
H
H
F
H
H
H
F
H
heptafluoroisopropyl
H
Cl


6-956
3-bromophenyl
H
H
F
H
H
H
F
H
heptafluoroisopropyl
H
Br


6-961
(2-trifluoromethyl) phenyl
H
H
F
H
H
H
F
H
heptafluoroisopropyl
H
I


6-964
2-nitrophenyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
Br


6-968
3-cyanophenyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


6-969
4-cyanophenyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


6-970
2,6-difluorophenyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
I


6-982
pyridin-3-yl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
I


6-984
2-chloropyridin-3-yl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


6-1026
phenyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


6-1046
3-cyanophenyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


6-1047
4-cyanophenyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


6-1062
2-chloropyridin-3-yl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


6-1104
phenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
Br


6-1105
2-fluorophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
Br


6-1106
3-fluorophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
Br


6-1107
4-fluorophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
Br


6-1124
3-cyanophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
Br


6-1125
4-cyanophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
Br


6-1126
2,6-difluorophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
Br


6-1140
2-chloropyridin-3-yl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
Br


6-1147
6-chloropyridin-3-yl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
Br


6-1182
phenyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


6-1183
2-fluorophenyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


6-1184
3-fluorophenyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


6-1185
4-fluorophenyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


6-1202
3-cyanophenyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


6-1203
4-cyanophenyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


6-1204
2,6-difluorophenyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


6-1218
2-chloropyridin-3-yl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


6-1225
6-chloropyridin-3-yl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


6-1260
phenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
I


6-1261
2-fluorophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
I


6-1262
3-fluorophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
I


6-1263
4-fluorophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
I


6-1280
3-cyanophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
I


6-1281
4-cyanophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
I


6-1282
2,6-difluorophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
I


6-1296
2-chloropyridin-3-yl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
I


6-1303
6-chloropyridin-3-yl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
I


6-1338
phenyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
I


6-1339
2-fluorophenyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
I


6-1340
3-fluorophenyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
I


6-1341
4-fluorophenyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
I


6-1358
3-cyanophenyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
I


6-1359
4-cyanophenyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
I


6-1360
2,6-difluorophenyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
I


6-1374
2-chloropyridin-3-yl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
I


6-1381
6-chloropyridin-3-yl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
I


6-1416
phenyl
H
H
F
H
H
H
F
H
heptafluoroisopropyl
H
CF3


6-1417
phenyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-1418
2-fluorophenyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-1422
3-chlorophenyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-1426
4-bromophenyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-1427
2-iodophenyl
H
H
F
H
H
H
Cl
H
pentafluoroethyl
H
CF3


6-1431
(3-trifluoromethyl) phenyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-1435
4-nitrophenyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-1436
2-cyanophenyl
H
H
F
H
H
H
Cl
H
pentafluoroethyl
H
C2F5


6-1437
3-cyanophenyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-1438
4-cyanophenyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-1439
2,6-difluorophenyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-1440
3,4-dichlorophenyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-1441
2,4-dichlorophenyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
C2F5


6-1442
2-chloro-4-fluorophenyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-1445
2-bromo-4-chlorophenyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


6-1446
2-bromo-4-fluorophenyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-1447
2-chloro-4-nitrophenyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-1448
3,5-dicyanophenyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-1449
4-cyano-2-fluorophenyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-1451
pyridin-3-yl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-1452
2-fluoropyridin-3-yl
H
H
F
H
H
H
Cl
H
pentafluoroethyl
H
CF3


6-1453
2-chloropyridin-3-yl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-1456
2-(fluoromethyl) pyridin-3-yl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-1457
2-nitropyridin-3-yl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


6-1460
6-chloropyridin-3-yl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
i-C3F7


6-1467
5-chloropyridin-3-yl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-1474
4-chloropyridin-3-yl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-1480
2,6-dichloropyridin-3-yl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-1481
pyridin-3-yl N-oxide
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-1482
pyridin-4-yl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-1483
2-chloropyridin-4-yl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-1485
3,5-dichloropyridin-4-yl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-1488
pyridin-4-yl N-oxide
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-1489
pyridin-2-yl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-1490
3-chloropyridin-2-yl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-1493
6-chloropyridin-2-yl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-1495
phenyl
H
H
F
H
H
H
F
H
nonafluoro-2-butyl
H
CF3


6-1496
phenyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


6-1498
3-fluorophenyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


6-1502
4-chlorophenyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


6-1503
2-bromophenyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


6-1507
3-iodophenyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


6-1511
(4-trifluoromethyl) phenyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


6-1512
2-nitrophenyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


6-1516
3-cyanophenyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


6-1517
4-cyanophenyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


6-1518
2,6-difluorophenyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


6-1520
2,4-dichlorophenyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


6-1521
2-chloro-4-fluorophenyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


6-1524
2-bromo-4-chlorophenyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


6-1525
2-bromo-4-fluorophenyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


6-1526
2-chloro-4-nitrophenyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


6-1528
4-cyano-2-fluorophenyl
H
H
F
H
H
H
Cl
H
nonefluoro-2-butyl
H
CF3


6-1529
2-chloro-4-cyanophenyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


6-1530
pyridin-3-yl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


6-1532
2-chloropyridin-3-yl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


6-1539
6-chloropyridin-3-yl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


6-1545
5-fluoropyrdin-3-yl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


6-1552
4-fluoropyridin-3-yl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


6-1559
2,6-dichloropyridin-3-yl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


6-1560
pyridin-3-yl N-oxide
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


6-1561
pyridin-4-yl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


6-1562
2-chloropyridin-4-yl
H
H
F
H
H
H
CI
H
nonafluoro-2-butyl
H
CF3


6-1567
pyridin-4-yl N-oxide
H
H
F
H
H
H
CI
H
nonafluoro-2-butyl
H
CF3


6-1568
pyridin-2-yl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


6-1569
3-chloropyridin-2-yl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


6-1572
6-chloropyridin-2-yl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


6-1574
phenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1575
2-fluorophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1576
3-fluorophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1577
4-fluorophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1578
2-chlorophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1579
3-chlorophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1580
4-chlorophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1581
2-bromophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1582
3-bromophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1583
4-bromophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1584
2-iodophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1585
3-iodophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1586
4-iodophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1587
(2-trifluoromethyl) phenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1588
(3-trifluoromethyl) phenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1589
(4-trifluoromethyl) phenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1590
2-nitrophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1591
3-nitrophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1592
4-nitrophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1593
2-cyanophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1594
3-cyanophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1595
4-cyanophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1596
2,6-difluorophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1597
3,4-dichlorophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1598
2,4-dichlorophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1599
2-chloro-4-fluorophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1600
2-chloro-4,5-difluorophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1601
4-bromo-2-chlorophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1602
2-bromo-4-chlorophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1603
2-bromo-4-fluorophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1604
2-chloro-4-nitrophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1605
3,5-dicyanophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1606
4-cyano-2-fluorophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1607
2-chloro-4-cyanophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1608
pyridin-3-yl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1609
2-fluoropyridin-3-yl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1610
2-chloropyridin-3-yl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1611
2-bromopyridin-3-yl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1612
2-iodopyridin-3-yl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1613
2-(trifluoromethyl) pyridin-3-yl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1614
2-nitropyridin-3-yl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1615
2-cyanopyridin-3-yl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1616
6-fluoropyridin-3-yl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1617
6-chloropyridin-3-yl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1618
6-bromopyridin-3-yl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1619
6-iodopyridin-3-yl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1620
6-(trifluoremethyl) pyridin-3-yl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1621
6-nitropyridin-3-yl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1622
6-cyanopyridin-3-yl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1623
5-fluoropyridin-3-yl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1624
5-chloropyridin-3-yl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1625
5-bromopyridin-3-yl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1626
5-iodopyridin-3-yl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1627
5-(trifluoromethyl) pyridin-3-yl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1628
5-nitropyridin-3-yl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1629
5-cyanopyridin-3-yl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1630
4-fluoropyridin-3-yl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1631
4-chloropyridin-3-yl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1632
4-bromopyridin-3-yl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1633
4-iodopyridin-3-yl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1634
4-(trifluoromethyl) pyridin-3-yl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1635
4-nitropyridin-3-yl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1636
4-cyanopyridin-3-yl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1637
2,6-dichloropyridin-3-yl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1638
pyridin-3-yl N-oxide
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1639
pyridin-4-yl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1640
2-chloropyridin-4-yl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1641
3-bromopyridin-4-yl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1642
3,5-dichloropyridin-4-yl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1643
3-(trifluoromethyl) pyridin-4-yl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1644
2,6-dicyanopyridin-4-yl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1645
pyridin-4-yl N-oxide
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1646
pyridin-2-yl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1647
3-chloropyridin-2-yl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1648
4-bromopyridin-2-yl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1649
5-iodopyridin-2-yl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1650
6-chloropyridin-2-yl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1651
4-cyanopyridin-2-yl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1652
phenyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1653
2-fluorophenyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1654
3-fluorophenyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1655
4-fluorophenyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1656
2-chlorophenyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1657
3-chlorophenyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1658
4-chlorophenyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1659
2-bromophenyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1660
3-bromophenyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1661
4-bromophenyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1662
2-iodophenyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1663
3-iodophenyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1664
4-iodophenyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1665
(2-trifluoromethyl) phenyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1666
(3-trifluoromethyl) phenyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1667
(4-trifluoromethyl) phenyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1668
2-nitrophenyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1669
3-nitrophenyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1670
4-nitrophenyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1671
2-cyanophenyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1672
3-cyanophenyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1673
4-cyanophenyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1674
2,6-difluorophenyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1675
3,4-dichlorophenyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1676
2,4-dichlorophenyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1677
2-chloro-4-fluorophenyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1678
2-chloro-4,5-difluorophenyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1679
4-bromo-2-chlorophenyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1680
2-bromo-4-chlorophenyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1681
2-bromo-4-fluorophenyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1682
2-chloro-4-nitrophenyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1683
3,5-dicyanophenyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1684
4-cyano-2-fluorophenyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1685
2-chloro-4-cyanophenyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1686
pyridin-3-yl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1687
2-fluoropyridin-3-yl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1688
2-chloropyridin-3-yl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1689
2-bromopyridin-3-yl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1690
2-iodopyridin-3-yl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1691
2-(trifluoromethyl) pyridin-3-yl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1692
2-nitropyridin-3-yl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1693
2-cyanopyridin-3-yl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1694
6-fluoropyridin-3-yl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1695
6-chloropyridin-3-yl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1696
6-bromopyridin-3-yl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1697
6-iodopyridin-3-yl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1698
6-(trifluoromethyl) pyridin-3-yl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1699
6-nitropyridin-3-yl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1700
6-cyanopyridin-3-yl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1701
5-fluoropyridin-3-yl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1702
5-chloropyridin-3-yl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1703
5-bromopyridin-3-yl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1704
5-iodopyridin-3-yl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1705
5-(trifluoromethyl) pyridin-3-yl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1706
5-nitropyridin-3-yl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1707
5-cyanopyridin-3-yl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1708
4-fluoropyridin-3-yl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1709
4-chloropyridin-3-yl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1710
4-bromopyridin-3-yl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1711
4-iodopyridin-3-yl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1712
4-(trifluoromethyl) pyridin-3-yl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1713
4-nitropyridin-3-yl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1714
4-cyanopyridin-3-yl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1715
2,6-dichloropyridin-3-yl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1716
pyridin-3-yl N-oxide
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1717
pyridin-4-yl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1718
2-chloropyridin-4-yl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1719
3-bromopyridin-4-yl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1720
3,5-dichloropyridin-4-yl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1721
3-(trifluoromethyl) pyridin-4-yl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1722
2,6-dicyanopyridin-4-yl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1723
pyridin-4-yl N-oxide
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1724
pyridin-2-yl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1725
3-chloropyridin-2-yl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1726
4-bromopyridin-2-yl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1727
5-iodopyridin-2-yl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1728
6-chloropyridin-2-yl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1729
4-cyanopyridin-2-yl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-1730
phenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1731
2-fluorophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1732
3-fluorophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1733
4-fluorophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1734
2-chlorophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1735
3-chlorophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1736
4-chlorophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1737
2-bromophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1738
3-bromophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1739
4-bromophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1740
2-iodophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1741
3-iodophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1742
4-iodophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1743
(2-trifluoromethyl) phenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1744
(3-trifluoromethyl) phenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1745
(4-trifluoromethyl) phenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1746
2-nitrophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1747
3-nitrophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1748
4-nitrophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1749
2-cyanophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1750
3-cyanophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1751
4-cyanophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1752
2,6-difluorophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1753
3,4-dichlorophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1754
2,4-dichlorophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1755
2-chloro-4-fluorophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1756
2-chloro-4,5-difluorophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1757
4-bromo-2-chlorophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1758
2-bromo-4-chlorophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1759
2-bromo-4-fluorophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1760
2-chloro-4-nitrophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1761
3,5-dicyanophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1762
4-cyano-2-fluorophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1763
2-chloro-4-cyanophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1764
pyridin-3-yl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1765
2-fluoropyridin-3-yl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1766
2-chloropyridin-3-yl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1767
2-bromopyridin-3-yl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1768
2-iodopyridin-3-yl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1769
2-(trifluoromethyl) pyridin-3-yl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1770
2-nitropyridin-3-yl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1771
2-cyanopyridin-3-yl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1772
6-fluoropyridin-3-yl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1773
6-chloropyridin-3-yl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1774
6-bromopyridin-3-yl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1775
6-iodopyridin-3-yl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1776
6-(trifluoromethyl) pyridin-3-yl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1777
6-nitropyridin-3-yl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1778
6-cyanopyridin-3-yl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1779
5-fluoropyridin-3-yl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1780
5-chloropyridin-3-yl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1781
5-bromopyridin-3-yl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1782
5-iodopyridin-3-yl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1783
5-(trifluoromethyl) pyridin-3-yl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1784
5-nitropyridin-3-yl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1785
5-cyanopyridin-3-yl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1786
4-fluoropyridin-3-yl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1787
4-chloropyridin-3-yl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1788
4-bromopyridin-3-yl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1789
4-iodopyridin-3-yl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1790
4-(trifluoromethyl) pyridin-3-yl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1791
4-nitropyridin-3-yl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1792
4-cyanopyridin-3-yl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1793
2,6-dichloropyridin-3-yl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1794
pyridin-3-yl N-oxide
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1795
pyridin-4-yl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1796
2-chloropyridin-4-yl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1797
3-bromopyridin-4-yl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1798
3,5-dichloropyridin-4-yl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1799
3-(trifluoromethyl) pyridin-4-yl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1800
2,6-dicyanopyridin-4-yl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1801
pyridin-4-yl N-oxide
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1802
pyridin-2-yl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1803
3-chloropyridin-2-yl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1804
4-bromopyridin-2-yl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1805
5-iodopyridin-2-yl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1806
6-chloropyridin-2-yl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1807
4-cyanopyridin-2-yl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1808
phenyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1809
2-fluorophenyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1810
3-fluorophenyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1811
4-fluorophenyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1812
2-chlorophenyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1813
3-chlorophenyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1814
4-chlorophenyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1815
2-bromophenyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1816
3-bromophenyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1817
4-bromophenyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1818
2-iodophenyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1819
3-iodophenyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1820
4-iodophenyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1821
(2-trifluoromethyl) phenyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1822
(3-trifluoromethyl) phenyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1823
(4-trifluoromethyl) phenyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1824
2-nitrophenyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1825
3-nitrophenyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1826
4-nitrophenyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1827
2-cyanophenyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1828
3-cyanophenyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1829
4-cyanophenyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1830
2,6-difluorophenyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1831
3,4-dichlorophenyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1832
2,4-dichlorophenyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1833
2-chloro-4-fluorophenyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1834
2-chloro-4,5-difluorophenyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1835
4-bromo-2-chlorophenyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1836
2-bromo-4-chlorophenyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1837
2-bromo-4-fluorophenyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1838
2-chloro-4-nitrophenyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1839
3,5-dicyanophenyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1840
4-cyano-2-fluorophenyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1841
2-chloro-4-cyanophenyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1842
pyridin-3-yl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1843
2-fluoropyridin-3-yl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1844
2-chloropyridin-3-yl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1845
2-bromopyridin-3-yl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1846
2-iodopyrdin-3-yl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1847
2-(trifluoromethyl) pyridin-3-yl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1848
2-nitropyridin-3-yl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1849
2-cyanopyridin-3-yl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1850
6-fluoropyrdin-3-yl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1851
6-chloropyridin-3-yl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1852
6-bromopyridin-3-yl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1853
6-iodopyridin-3-yl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1854
6-(trifluoromethyl) pyridin-3-yl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1855
6-nitropyridin-3-yl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1856
6-cyanopyridin-3-yl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1857
5-fluoropyridin-3-yl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1858
5-chloropyridin-3-yl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1859
5-bromopyridin-3-yl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1860
5-iodopyridin-3-yl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1861
5-(trifluoromethyl) pyridin-3-yl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1862
5-nitropyridin-3-yl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1863
5-cyanopyridin-3-yl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1864
4-fluoropyridin-3-yl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1865
4-chloropyridin-3-yl
H
H
F
H
H
H
1
H
nonafluoro-2-butyl
H
CF3


6-1866
4-bromopyridin-3-yl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1867
4-iodopyridin-3-yl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1868
4-(trifluoromethyl) pyridin-3-yl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1869
4-nitropyridin-3-yl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1870
4-cyanopyridin-3-yl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1871
2,6-dichloropyridin-3-yl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1872
pyridin-3-yl N-oxide
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1873
pyridin-4-yl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1874
2-chloropyridin-4-yl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1875
3-bromopyridin-4-yl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1876
3,5-dichloropyridin-4-yl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1877
3-(trifluoromethyl) pyridin-4-yl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1878
2,6-dicyanopyridin-4-yl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1879
pyridin-4-yl N-oxide
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1880
pyridin-2-yl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1881
3-chloropyridin-2-yl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1882
4-bromopyridin-2-yl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1883
5-iodopyridin-2-yl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1884
6-chloropyridin-2-yl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1885
4-cyanopyridin-2-yl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-1886
phenyl
H
H
F
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


6-1901
3-cyanophenyl
H
H
F
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


6-1902
4-cyanophenyl
H
H
F
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


6-1917
2-chloropyridin-3-yl
H
H
F
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


6-1942
phenyl
H
H
F
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


6-1957
3-cyanophenyl
H
H
F
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


6-1958
4-cyanophenyl
H
H
F
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


6-1973
2-chloropyridin-3-yl
H
H
F
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


6-1998
phenyl
H
H
F
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


6-2013
3-cyanophenyl
H
H
F
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


6-2014
4-cyanophenyl
H
H
F
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


6-2029
2-chloropyridin-3-yl
H
H
F
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


6-2054
phenyl
H
H
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


6-2069
3-cyanophenyl
H
H
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


6-2070
4-cyanophenyl
H
H
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


6-2085
2-chloropyridin-3-yl
H
H
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


6-2110
phenyl
H
H
F
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


6-2130
3-cyanophenyl
H
H
F
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


6-2131
4-cyanophenyl
H
H
F
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


6-2146
2-chloropyridin-3-yl
H
H
F
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


6-2178
phenyl
H
H
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


6-2198
3-cyanophenyl
H
H
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


6-2199
4-cyanophenyl
H
H
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


6-2214
2-chloropyridin-3-yl
H
H
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


6-2246
phenyl
H
H
H
F
H
H
F
H
heptafluoroisopropyl
H
F


6-2247
3-cyanophenyl
H
H
H
F
H
H
F
H
heptafluoroisopropyl
H
F


6-2248
4-cyanophenyl
H
H
H
F
H
H
F
H
heptafluoroisopropyl
H
F


6-2249
2-chloropyridin-3-yl
H
H
H
F
H
H
F
H
heptafluoroisopropyl
H
F


6-2250
phenyl
H
H
H
F
H
H
F
H
nonafluoro-2-butyl
H
F


6-2251
3-cyanophenyl
H
H
H
F
H
H
F
H
nonafluoro-2-butyl
H
F


6-2252
4-cyanophenyl
H
H
H
F
H
H
F
H
nonafluoro-2-butyl
H
F


6-2253
2-chloropyridin-3-yl
H
H
H
F
H
H
F
H
nonafluoro-2-butyl
H
F


6-2254
phenyl
H
H
H
F
H
H
Cl
H
heptafluoroisopropyl
H
Cl


6-2274
3-cyanophenyl
H
H
H
F
H
H
Cl
H
heptafluoroisopropyl
H
Cl


6-2275
4-cyanophenyl
H
H
H
F
H
H
Cl
H
heptafluoroisopropyl
H
Cl


6-2290
2-chloropyridin-3-yl
H
H
H
F
H
H
Cl
H
heptafluoroisopropyl
H
Cl


6-2332
phenyl
H
H
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


6-2352
3-cyanophenyl
H
H
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


6-2353
4-cyanophenyl
H
H
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


6-2368
2-chloropyridin-3-yl
H
H
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


6-2410
phenyl
H
H
H
F
H
H
Br
H
heptafluoroisopropyl
H
Br


6-2430
3-cyanophenyl
H
H
H
F
H
H
Br
H
heptafluoroisopropyl
H
Br


6-2431
4-cyanophenyl
H
H
H
F
H
H
Br
H
heptafluoroisopropyl
H
Br


6-2446
2-chloropyridin-3-yl
H
H
H
F
H
H
Br
H
heptafluoroisopropyl
H
Br


6-2488
phenyl
H
H
H
F
H
H
Br
H
nonafluoro-2-butyl
H
Br


6-2508
3-cyanophenyl
H
H
H
F
H
H
Br
H
nonafluoro-2-butyl
H
Br


6-2509
4-cyanophenyl
H
H
H
F
H
H
Br
H
nonafluoro-2-butyl
H
Br


6-2524
2-chloropyridin-3-yl
H
H
H
F
H
H
Br
H
nonafluoro-2-butyl
H
Br


6-2566
phenyl
H
H
H
F
H
H
I
H
heptafluoroisopropyl
H
I


6-2586
3-cyanophenyl
H
H
H
F
H
H
I
H
heptafluoroisopropyl
H
I


6-2587
4-cyanophenyl
H
H
H
F
H
H
I
H
heptafluoroisopropyl
H
I


6-2602
2-chloropyridin-3-yl
H
H
H
F
H
H
I
H
heptafluoroisopropyl
H
I


6-2644
phenyl
H
H
H
F
H
H
I
H
nonafluoro-2-butyl
H
I


6-2664
3-cyanophenyl
H
H
H
F
H
H
I
H
nonafluoro-2-butyl
H
I


6-2665
4-cyanophenyl
H
H
H
F
H
H
I
H
nonafluoro-2-butyl
H
I


6-2680
2-chloropyridin-3-yl
H
H
H
F
H
H
I
H
nonafluoro-2-butyl
H
I


6-2722
phenyl
H
H
H
F
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


6-2742
3-cyanophenyl
H
H
H
F
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


6-2743
4-cyanophenyl
H
H
H
F
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


6-2758
2-chloropyridin-3-yl
H
H
H
F
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


6-2800
phenyl
H
H
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


6-2820
3-cyanophenyl
H
H
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


6-2821
4-cyanophenyl
H
H
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


6-2836
2-chloropyridin-3-yl
H
H
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


6-2878
phenyl
H
H
H
F
H
H
Br
H
heptafluoroisopropyl
H
OCF3


6-2898
3-cyanophenyl
H
H
H
F
H
H
Br
H
heptafluoroisopropyl
H
OCF3


6-2899
4-cyanophenyl
H
H
H
F
H
H
Br
H
heptafluoroisopropyl
H
OCF3


6-2914
2-chloropyridin-3-yl
H
H
H
F
H
H
Br
H
heptafluoroisopropyl
H
OCF3


6-2956
phenyl
H
H
H
F
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


6-2976
3-cyanophenyl
H
H
H
F
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


6-2977
4-cyanophenyl
H
H
H
F
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


6-2992
2-chloropyriclin-3-yl
H
H
H
F
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


6-3034
phenyl
H
H
H
F
H
H
I
H
heptafluoroisopropyl
H
OCF3


6-3054
3-cyanophenyl
H
H
H
F
H
H
I
H
heptafluoroisopropyl
H
OCF3


6-3055
4-cyanophenyl
H
H
H
F
H
H
I
H
heptafluoroisopropyl
H
OCF3


6-3070
2-chloropyridin-3-yl
H
H
H
F
H
H
I
H
heptafluoroisopropyl
H
OCF3


6-3112
phenyl
H
H
H
F
H
H
I
H
nonafluoro-2-butyl
H
OCF3


6-3132
3-cyanophenyl
H
H
H
F
H
H
I
H
nonafluoro-2-butyl
H
OCF3


6-3133
4-cyanophenyl
H
H
H
F
H
H
I
H
nonafluoro-2-butyl
H
OCF3


6-3148
2-chloropyridin-3-yl
H
H
H
F
H
H
I
H
nonafluoro-2-butyl
H
OCF3


6-3190
phenyl
H
H
H
F
H
H
F
H
heptafluoroisopropyl
H
CF3


6-3191
phenyl
H
H
H
F
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-3211
3-cyanophenyl
H
H
H
F
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-3212
4-cyanophenyl
H
H
H
F
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-3227
2-chloropyridin-3-yl
H
H
H
F
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-3269
phenyl
H
H
H
F
H
H
F
H
nonafluoro-2-butyl
H
CF3


6-3270
phenyl
H
H
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


6-3290
3-cyanophenyl
H
H
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


6-3291
4-cyanophenyl
H
H
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


6-3306
2-chloropyridin-3-yl
H
H
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


6-3348
phenyl
H
H
H
F
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-3368
3-cyanophenyl
H
H
H
F
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-3369
4-cyanophenyl
H
H
H
F
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-3384
2-chloropyridin-3-yl
H
H
H
F
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-3426
phenyl
H
H
H
F
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-3446
3-cyanophenyl
H
H
H
F
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-3447
4-cyanophenyl
H
H
H
F
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-3462
2-chloropyridin-3-yl
H
H
H
F
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-3504
phenyl
H
H
H
F
H
H
I
H
heptafluoroisopropyl
H
CF3


6-3524
3-cyanophenyl
H
H
H
F
H
H
I
H
heptafluoroisopropyl
H
CF3


6-3525
4-cyanophenyl
H
H
H
F
H
H
I
H
heptafluoroisopropyl
H
CF3


6-3540
2-chloropyridin-3-yl
H
H
H
F
H
H
I
H
heptafluoroisopropyl
H
CF3


6-3582
phenyl
H
H
H
F
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-3602
3-cyanophenyl
H
H
H
F
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-3603
4-cyanophenyl
H
H
H
F
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-3618
2-chloropyridin-3-yl
H
H
H
F
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-3660
phenyl
H
H
H
F
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


6-3675
3-cyanophenyl
H
H
H
F
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


6-3676
4-cyanophenyl
H
H
H
F
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


6-3691
2-chloropyridin-3-yl
H
H
H
F
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


6-3716
phenyl
H
H
H
F
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


6-3731
3-cyanophenyl
H
H
H
F
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


6-3732
4-cyanophenyl
H
H
H
F
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


6-3747
2-chloropyridin-3-yl
H
H
H
F
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


6-3772
phenyl
H
H
H
F
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


6-3787
3-cyanophenyl
H
H
H
F
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


6-3788
4-cyanophenyl
H
H
H
F
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


6-3803
2-chloropyridin-3-yl
H
H
H
F
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


6-3828
phenyl
H
H
H
F
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


6-3843
3-cyanophenyl
H
H
H
F
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


6-3844
4-cyanophenyl
H
H
H
F
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


6-3859
2-chloropyridin-3-yl
H
H
H
F
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


6-3884
phenyl
H
H
H
F
H
H
CF3
H
heptafluoroisopropyl
H
CF3


6-3904
3-cyanophenyl
H
H
H
F
H
H
CF3
H
heptafluoroisopropyl
H
CF3


6-3905
4-cyanophenyl
H
H
H
F
H
H
CF3
H
heptafluoroisopropyl
H
CF3


6-3920
2-chloropyridin-3-yl
H
H
H
F
H
H
CF3
H
heptafluoroisopropyl
H
CF3


6-3952
phenyl
H
H
H
F
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


6-3972
3-cyanophenyl
H
H
H
F
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


6-3973
4-cyanophenyl
H
H
H
F
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


6-3988
2-chloropyridin-3-yl
H
H
H
F
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


6-4020
phenyl
H
H
F
F
H
H
F
H
heptafluoroisopropyl
H
F


6-4021
3-cyanophenyl
H
H
F
F
H
H
F
H
heptafluoroisopropyl
H
F


6-4022
4-cyanophenyl
H
H
F
F
H
H
F
H
heptafluoroisopropyl
H
F


6-4023
2-chloropyridin-3-yl
H
H
F
F
H
H
F
H
heptafluoroisopropyl
H
F


6-4024
phenyl
H
H
F
F
H
H
F
H
nonafluoro-2-butyl
H
F


6-4025
3-cyanophenyl
H
H
F
F
H
H
F
H
nonafluoro-2-butyl
H
F


6-4026
4-cyanophenyl
H
H
F
F
H
H
F
H
nonafluoro-2-butyl
H
F


6-4027
2-chlorpyridin-3-yl
H
H
F
F
H
H
F
H
nonafluoro-2-butyl
H
F


6-4028
phenyl
H
H
F
F
H
H
Cl
H
heptafluoroisopropyl
H
Cl


6-4048
3-cyanophenyl
H
H
F
F
H
H
Cl
H
heptafluoroisopropyl
H
Cl


6-4049
4-cyanophenyl
H
H
F
F
H
H
Cl
H
heptafluoroisopropyl
H
Cl


6-4064
2-chlorphenyl-3-yl
H
H
F
F
H
H
Cl
H
heptafluoroisopropyl
H
Cl


6-4106
phenyl
H
H
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


6-4126
3-cyanophenyl
H
H
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


6-4127
4-cyanophenyl
H
H
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


6-4142
2-chloropyridin-3-yl
H
H
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


6-4184
phenyl
H
H
F
F
H
H
Br
H
heptafluoroisopropyl
H
Br


6-4204
3-cyanophenyl
H
H
F
F
H
H
Br
H
heptafluoroisopropyl
H
Br


6-4205
4-cyanophenyl
H
H
F
F
H
H
Br
H
heptafluoroisopropyl
H
Br


6-4220
2-chloropyridin-3-yl
H
H
F
F
H
H
Br
H
heptafluoroisopropyl
H
Br


6-4262
phenyl
H
H
F
F
H
H
Br
H
nonafluoro-2-butyl
H
Br


6-4282
3-cyanophenyl
H
H
F
F
H
H
Br
H
nonafluoro-2-butyl
H
Br


6-4283
4-cyanophenyl
H
H
F
F
H
H
Br
H
nonafluoro-2-butyl
H
Br


6-4298
2-chloropyrid6-3-yl
H
H
F
F
H
H
Br
H
nonafluoro-2-butyl
H
Br


6-4340
phenyl
H
H
F
F
H
H
I
H
heptafluoroisopropyl
H
I


6-4360
3-cyanophenyl
H
H
F
F
H
H
I
H
heptafluoroisopropyl
H
I


6-4361
4-cyanophenyl
H
H
F
F
H
H
I
H
heptafluoroisopropyl
H
I


6-4376
2-chloropyridin-3-yl
H
H
F
F
H
H
I
H
heptafluoroisopropyl
H
I


6-4418
phenyl
H
H
F
F
H
H
I
H
nonafluoro-2-butyl
H
I


6-4438
3-cyanophenyl
H
H
F
F
H
H
I
H
nonafluoro-2-butyl
H
I


6-4439
4-cyanophenyl
H
H
F
F
H
H
I
H
nonafluoro-2-butyl
H
I


6-4454
2-chloropyridin-3-yl
H
H
F
F
H
H
I
H
nonafluoro-2-butyl
H
I


6-4496
phenyl
H
H
F
F
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


6-4516
3-cyanophenyl
H
H
F
F
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


6-4517
4-cyanophenyl
H
H
F
F
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


6-4532
2-chloropyridin-3-yl
H
H
F
F
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


6-4574
phenyl
H
H
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


6-4594
3-cyanophenyl
H
H
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


6-4595
4-cyanophenyl
H
H
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


6-4610
2-chloropyridin-3-yl
H
H
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


6-4652
phenyl
H
H
F
F
H
H
Br
H
heptafluoroisopropyl
H
OCF3


6-4672
3-cyanophenyl
H
H
F
F
H
H
Br
H
heptafluoroisopropyl
H
OCF3


6-4673
4-cyanophenyl
H
H
F
F
H
H
Br
H
heptafluoroisopropyl
H
OCF3


6-4688
2-chloropyridin-3-yl
H
H
F
F
H
H
Br
H
heptafluoroisopropyl
H
OCF3


6-4730
phenyl
H
H
F
F
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


6-4750
3-cyanophenyl
H
H
F
F
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


6-4751
4-cyanophenyl
H
H
F
F
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


6-4766
2-chloropyridin-3-yl
H
H
F
F
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


6-4808
phenyl
H
H
F
F
H
H
I
H
heptafluoroisopropyl
H
OCF3


6-4828
3-cyanophenyl
H
H
F
F
H
H
I
H
heptafluoroisopropyl
H
OCF3


6-4829
4-cyanophenyl
H
H
F
F
H
H
I
H
heptafluoroisopropyl
H
OCF3


6-4844
2-chloropyridin-3-yl
H
H
F
F
H
H
I
H
heptafluoroisopropyl
H
OCF3


6-4886
phenyl
H
H
F
F
H
H
I
H
nonafluoro-2-butyl
H
OCF3


6-4906
3-cyanophenyl
H
H
F
F
H
H
I
H
nonafluoro-2-butyl
H
OCF3


6-4907
4-cyanophenyl
H
H
F
F
H
H
I
H
nonafluoro-2-butyl
H
OCF3


6-4922
2-chloropyridin-3-yl
H
H
F
F
H
H
I
H
nonafluoro-2-butyl
H
OCF3


6-4964
phenyl
H
H
F
F
H
H
F
H
heptafluoroisopropyl
H
CF3


6-4965
phenyl
H
H
F
F
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-4985
3-cyanophenyl
H
H
F
F
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-4986
4-cyanophenyl
H
H
F
F
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-5001
2-chloropyridin-3-yl
H
H
F
F
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-5043
phenyl
H
H
F
F
H
H
F
H
nonafluoro-2-butyl
H
CF3


6-5044
phenyl
H
H
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


6-5064
3-cyanophenyl
H
H
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


6-5065
4-cyanophenyl
H
H
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


6-5080
2-chloropyridin-3-yl
H
H
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


6-5122
phenyl
H
H
F
F
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-5142
3-cyanophenyl
H
H
F
F
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-5143
4-cyanophenyl
H
H
F
F
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-5158
2-chloropyridin-3-yl
H
H
F
F
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-5200
phenyl
H
H
F
F
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-5220
3-cyanophenyl
H
H
F
F
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-5221
4-cyanophenyl
H
H
F
F
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-5236
2-chloropyridin-3-yl
H
H
F
F
H
H
Br
H
nonafluoro-2-butyl
H
CF3


6-5278
phenyl
H
H
F
F
H
H
I
H
heptafluoroisopropyl
H
CF3


6-5298
3-cyanophenyl
H
H
F
F
H
H
I
H
heptafluoroisopropyl
H
CF3


6-5299
4-cyanophenyl
H
H
F
F
H
H
I
H
heptafluoroisopropyl
H
CF3


6-5314
2-chlorpyridin-3-yl
H
H
F
F
H
H
I
H
heptafluoroisopropyl
H
CF3


6-5356
phenyl
H
H
F
F
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-5376
3-cyanophenyl
H
H
F
F
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-5377
4-cyanophenyl
H
H
F
F
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-5392
2-chloropyridin-3-yl
H
H
F
F
H
H
I
H
nonafluoro-2-butyl
H
CF3


6-5434
phenyl
H
H
F
F
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


6-5449
3-cyanophenyl
H
H
F
F
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


6-5450
4-cyanophenyl
H
H
F
F
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


6-5465
2-chloropyridin-3-yl
H
H
F
F
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


6-5490
phenyl
H
H
F
F
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


6-5505
3-cyanophenyl
H
H
F
F
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


6-5506
4-cyanophenyl
H
H
F
F
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


6-5521
2-chloropyridin-3-yl
H
H
F
F
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


6-5546
phenyl
H
H
F
F
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


6-5561
3-cyanophenyl
H
H
F
F
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


6-5562
4-cyanophenyl
H
H
F
F
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


6-5577
2-chloropyridin-3-yl
H
H
F
F
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


6-5602
phenyl
H
H
F
F
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


6-5617
3-cyanophenyl
H
H
F
F
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


6-5633
2-chloropyridin-3-yl
H
H
F
F
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


6-5658
phenyl
H
H
F
F
H
H
CF3
H
heptafluoroisopropyl
H
CF3


6-5678
3-cyanophenyl
H
H
F
F
H
H
CF3
H
heptafluoroisopropyl
H
CF3


6-5694
2-chloropyridin-3-yl
H
H
F
F
H
H
CF3
H
heptafluoroisopropyl
H
CF3


6-5726
phenyl
H
H
F
F
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


6-5746
3-cyanophenyl
H
H
F
F
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


6-5747
4-cyanophenyl
H
H
F
F
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


6-5762
2-chloropyridin-3-yl
H
H
F
F
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


6-5794
phenyl
H
H
F
F
F
H
Cl
H
pentafluoroethyl
H
Cl


6-5795
phenyl
H
H
F
F
F
H
Br
H
heptafluoroisopropyl
H
Br


6-5796
phenyl
H
H
F
F
F
H
Br
H
heptafluoroisopropyl
H
OCF3


6-5797
phenyl
H
H
F
F
F
H
I
H
heptafluoroisopropyl
H
CF3


6-5798
phenyl
H
H
F
F
F
H
CF3
H
heptafluoroisopropyl
H
CF3


6-5799
phenyl
H
H
F
F
F
H
I
H
nonafluoro-2-butyl
H
I


6-5800
phenyl
H
H
F
F
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


6-5801
phenyl
H
H
F
F
F
H
Br
H
nonafluoro-2-butyl
H
CF3


6-5802
phenyl
H
H
F
F
F
H
CF3
H
nonafluoro-2-butyl
H
CF3


6-5803
phenyl
H
H
H
H
F
H
Cl
H
pentafluoroethyl
H
Cl


6-5804
phenyl
H
H
H
H
F
H
Br
H
heptafluoroisopropyl
H
Br


6-5805
phenyl
H
H
H
H
F
H
Br
H
heptafluoroisopropyl
H
OCF3


6-5806
phenyl
H
H
H
H
F
H
I
H
heptafluoroisopropyl
H
CF3


6-5807
phenyl
H
H
H
H
F
H
CF3
H
heptafluoroisopropyl
H
CF3


6-5808
phenyl
H
H
H
H
F
H
I
H
nonafluoro-2-butyl
H
I


6-5809
phenyl
H
H
H
H
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


6-5810
phenyl
H
H
H
H
F
H
Br
H
nonafluoro-2-butyl
H
CF3


6-5811
phenyl
H
H
H
H
F
H
CF3
H
nonafluoro-2-butyl
H
CF3


6-5812
phenyl
H
H
H
H
H
F
Cl
H
pentafluoroethyl
H
Cl


6-5813
phenyl
H
H
H
H
H
F
Br
H
heptafluoroisopropyl
H
Br


6-5814
phenyl
H
H
H
H
H
F
Br
H
heptafluoroisopropyl
H
OCF3


6-5815
phenyl
H
H
H
H
H
F
I
H
heptafluoroisopropyl
H
CF3


6-5816
phenyl
H
H
H
H
H
F
CF3
H
heptafluoroisopropyl
H
CF3


6-5817
phenyl
H
H
H
H
H
F
I
H
nonafluoro-2-butyl
H
I


6-5818
phenyl
H
H
H
H
H
F
CI
H
nonafluoro-2-butyl
H
OCF3


6-5819
phenyl
H
H
H
H
H
F
Br
H
nonafluoro-2-butyl
H
CF3


6-5820
phenyl
H
H
H
H
H
F
CF3
H
nonafluoro-2-butyl
H
CF3


6-5821
phenyl
H
H
F
H
F
H
Cl
H
pentafluoroethyl
H
CI


6-5822
phenyl
H
H
F
H
F
H
Br
H
heptafluoroisopropyl
H
Br


6-5823
phenyl
H
H
F
H
F
H
Br
H
heptafluoroisopropyl
H
OCF3


6-5824
phenyl
H
H
F
H
F
H
I
H
heptafluoroisopropyl
H
CF3


6-5825
phenyl
H
H
F
H
H
F
CF3
H
heptafluoroisopropyl
H
CF3


6-5826
phenyl
H
H
F
H
H
F
I
H
nonafluoro-2-butyl
H
I


6-5827
phenyl
H
H
F
H
H
F
Cl
H
nonafluoro-2-butyl
H
OCF3


6-5828
phenyl
H
H
F
H
H
F
Br
H
nonafluoro-2-butyl
H
CF3


6-5829
phenyl
H
H
F
H
H
F
CF3
H
nonafluoro-2-butyl
H
CF3


6-5830
phenyl
H
H
F
H
H
F
Cl
H
pentafluoroethyl
H
Cl


6-5831
phenyl
H
H
F
H
H
F
Br
H
heptafluoroisopropyl
H
Br


6-5832
phenyl
H
H
F
H
H
F
Br
H
heptafluoroisopropyl
H
OCF3


6-5833
phenyl
H
H
F
H
H
F
I
H
heptafluoroisopropyl
H
CF3


6-5834
phenyl
H
H
F
H
H
F
CF3
H
heptafluoroisopropyl
H
CF3


6-5835
phenyl
H
H
F
H
H
F
I
H
nonafluoro-2-butyl
H
I


6-5836
phenyl
H
H
F
H
H
F
Cl
H
nonafluoro-2-butyl
H
OCF3


6-5837
phenyl
H
H
F
H
H
F
Br
H
nonafluoro-2-butyl
H
CF3


6-5838
phenyl
H
H
F
H
H
F
CF3
H
nonafluoro-2-butyl
H
CF3


6-5839
phenyl
H
H
H
F
F
H
Cl
H
pentafluoroethyl
H
Cl


6-5840
phenyl
H
H
H
F
F
H
Br
H
heptafluoroisopropyl
H
Br


6-5841
phenyl
H
H
H
F
F
H
Br
H
heptafluoroisopropyl
H
OCF3


6-5842
phenyl
H
H
H
F
F
H
I
H
heptafluoroisopropyl
H
CF3


6-5843
phenyl
H
H
H
F
F
H
CF3
H
heptafluoroisopropyl
H
CF3


6-5844
phenyl
H
H
H
F
F
H
I
H
nonafluoro-2-butyl
H
I


6-5845
phenyl
H
H
H
F
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


6-5846
phenyl
H
H
H
F
F
H
Br
H
nonafluoro-2-butyl
H
CF3


6-5847
phenyl
H
H
H
F
F
H
CF3
H
nonafluoro-2-butyl
H
CF3


6-5848
phenyl
H
H
H
F
H
F
Cl
H
pentafluoroethyl
H
Cl


6-5849
phenyl
H
H
H
F
H
F
Br
H
heptafluoroisopropyl
H
Br


6-5850
phenyl
H
H
H
F
H
F
Br
H
heptafluoroisopropyl
H
OCF3


6-5851
phenyl
H
H
H
F
H
F
I
H
heptafluoroisopropyl
H
CF3


6-5852
phenyl
H
H
H
F
H
F
CF3
H
heptafluoroisopropyl
H
CF3


6-5853
phenyl
H
H
H
F
H
F
I
H
nonafluoro-2-butyl
H
I


6-5854
phenyl
H
H
H
F
H
F
Cl
H
nonafluoro-2-butyl
H
OCF3


6-5855
phenyl
H
H
H
F
H
F
Br
H
nonafluoro-2-butyl
H
CF3


6-5856
phenyl
H
H
H
F
H
F
CF3
H
nonafluoro-2-butyl
H
CF3


6-5857
phenyl
H
H
H
H
F
F
Cl
H
pentafluoroethyl
H
Cl


6-5858
phenyl
H
H
H
H
F
F
Br
H
heptafluoroisopropyl
H
Br


6-5859
phenyl
H
H
H
H
F
F
Br
H
heptafluoroisopropyl
H
OCF3


6-5860
phenyl
H
H
H
H
F
F
I
H
heptafluoroisopropyl
H
CF3


6-5861
phenyl
H
H
H
H
F
F
CF3
H
heptafluoroisopropyl
H
CF3


6-5862
phenyl
H
H
H
H
F
F
I
H
nonafluoro-2-butyl
H
I


6-5863
phenyl
H
H
H
H
F
F
Cl
H
nonafluoro-2-butyl
H
OCF3


6-5864
phenyl
H
H
H
H
F
F
Br
H
nonafluoro-2-butyl
H
CF3


6-5865
phenyl
H
H
H
H
F
F
CF3
H
nonafluoro-2-butyl
H
CF3


6-5866
phenyl
H
H
F
F
H
F
Cl
H
pentafluoroethyl
H
Cl


6-5867
phenyl
H
H
F
F
H
F
Br
H
heptafluoroisopropyl
H
Br


6-5868
phenyl
H
H
F
F
H
F
Br
H
heptafluoroisopropyl
H
OCF3


6-5869
phenyl
H
H
F
F
H
F
I
H
heptafluoroisopropyl
H
CF3


6-5870
phenyl
H
H
F
F
H
F
CF3
H
heptafluoroisopropyl
H
CF3


6-5871
phenyl
H
H
F
F
H
F
I
H
nonafluoro-2-butyl
H
I


6-5872
phenyl
H
H
F
F
H
F
Cl
H
nonafluoro-2-butyl
H
OCF3


6-5873
phenyl
H
H
F
F
H
F
Br
H
nonafluoro-2-butyl
H
CF3


6-5874
phenyl
H
H
F
F
H
F
CF3
H
nonafluoro-2-butyl
H
CF3


6-5875
phenyl
H
H
F
H
F
F
Cl
H
pentafluoroethyl
H
Cl


6-5876
phenyl
H
H
F
H
F
F
Br
H
heptafluoroisopropyl
H
Br


6-5877
phenyl
H
H
F
H
F
F
Br
H
heptafluoroisopropyl
H
OCF3


6-5878
phenyl
H
H
F
H
F
F
I
H
heptafluoroisopropyl
H
CF3


6-5879
phenyl
H
H
F
H
F
F
CF3
H
heptafluoroisopropyl
H
CF3


6-5880
phenyl
H
H
F
H
F
F
I
H
nonafluoro-2-butyl
H
I


6-5881
phenyl
H
H
F
H
F
F
Cl
H
nonafluoro-2-butyl
H
OCF3


6-5882
phenyl
H
H
F
H
F
F
Br
H
nonafluoro-2-butyl
H
CF3


6-5883
phenyl
H
H
F
H
F
F
CF3
H
nonafluoro-2-butyl
H
CF3


6-5884
phenyl
H
H
H
F
F
F
Cl
H
pentafluoroethyl
H
Cl


6-5885
phenyl
H
H
H
F
F
F
Br
H
heptafluoroisopropyl
H
Br


6-5886
phenyl
H
H
H
F
F
F
Br
H
heptafluoroisopropyl
H
OCF3


6-5887
phenyl
H
H
H
F
F
F
I
H
heptafluoroisopropyl
H
CF3


6-5888
phenyl
H
H
H
F
F
F
CF3
H
heptafluoroisopropyl
H
CF3


6-5889
phenyl
H
H
H
F
F
F
I
H
nonafluoro-2-butyl
H
I


6-5890
phenyl
H
H
F
F
F
F
Cl
H
nonafluoro-2-butyl
H
OCF3


6-5891
phenyl
H
H
F
F
F
F
Br
H
nonafluoro-2-butyl
H
CF3


6-5892
phenyl
H
H
F
F
F
F
CF3
H
nonafluoro-2-butyl
H
CF3


6-5893
phenyl
H
H
F
F
F
F
Cl
H
pentafluoroethyl
H
Cl


6-5894
phenyl
H
H
F
F
F
F
Br
H
heptafluoroisopropyl
H
Br


6-5895
phenyl
H
H
F
F
F
F
Br
H
heptafluoroisopropyl
H
OCF3


6-5896
phenyl
H
H
F
F
F
F
I
H
heptafluoroisopropyl
H
CF3


6-5897
phenyl
H
H
F
F
F
F
CF3
H
heptafluoroisopropyl
H
CF3


6-5898
phenyl
H
H
F
F
F
F
I
H
nonafluoro-2-butyl
H
I


6-5899
phenyl
H
H
F
F
F
F
Cl
H
nonafluoro-2-butyl
H
OCF3


6-5900
phenyl
H
H
F
F
F
F
Br
H
nonafluoro-2-butyl
H
CF3


6-5901
phenyl
H
H
F
F
F
F
CF3
H
nonafluoro-2-butyl
H
CF3


6-5902
phenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
Cl


6-5903
3-fluorophenyl
H
H
H
H
H
H
I
H
nonafluoro-2-butyl
H
I


6-5904
4-fluorophenyl
H
H
H
H
H
H
I
H
nonafluoro-2-butyl
H
I


6-5905
3-fluorophenyl
H
H
H
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


6-5906
4-fluorophenyl
H
H
H
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


6-5907
phenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


6-5908
2-chloropyridin-3-yl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


6-5909
4-cyanophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


6-5910
phenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
C2F5


6-5911
4-cyanophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
C2F5


6-5912
2-chloro-4-(methylsulfonyl) phenyl
H
H
H
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-5913
phenyl
H
H
H
H
H
H
Br
H
pentafluoroethyl
H
CF3


6-5914
2-chloropyridin-3-yl
H
H
H
H
H
H
Br
H
pentafluoroethyl
H
CF3











embedded image





















TABLE 7





compound














number
Q1
R1
R2
X1
X2
X3
X4
Y1
Y2
Y3
Y4
Y5







7-1
phenyl
Me
H
H
H
H
H
F
H
nonafluoro-2-butyl
H
F


7-2
3-cyanophenyl
Me
H
H
H
H
H
F
H
nonafluoro-2-butyl
H
F


7-3
4-cyanophenyl
Me
H
H
H
H
H
F
H
nonafluoro-2-butyl
H
F


7-4
2-chloropyridin-3-yl
Me
H
H
H
H
H
F
H
nonafluoro-2-butyl
H
F


7-5
phenyl
Me
H
H
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


7-12
3-cyanophenyl
Me
H
H
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


7-13
4-cyanophenyl
Me
H
H
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


7-24
2-chloropyridin-3-yl
Me
H
H
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


7-38
phenyl
Me
H
H
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


7-39
2-fluorophenyl
Me
H
H
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


7-45
3-cyanophenyl
Me
H
H
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


7-46
4-cyanophenyl
Me
H
H
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


7-47
2,6-difluorophenyl
Me
H
H
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


7-57
2-chloropyridin-3-yl
Me
H
H
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


7-60
6-chloropyridin-3-yl
Me
H
H
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


7-71
phenyl
Me
H
H
H
H
H
I
H
nonafluoro-2-butyl
H
I


7-72
2-fluorophenyl
Me
H
H
H
H
H
I
H
nonafluoro-2-butyl
H
I


7-78
3-cyanophenyl
Me
H
H
H
H
H
I
H
nonafluoro-2-butyl
H
I


7-79
4-cyanophenyl
Me
H
H
H
H
H
I
H
nonafluoro-2-butyl
H
I


7-80
2,6-difluorophenyl
Me
H
H
H
H
H
I
H
nonafluoro-2-butyl
H
I


7-90
2-chloropyridin-3-yl
Me
H
H
H
H
H
I
H
nonafluoro-2-butyl
H
I


7-93
6-chloropyridin-3-yl
Me
H
H
H
H
H
I
H
nonafluoro-2-butyl
H
I


7-104
phenyl
Me
H
H
H
H
H
F
H
nonafluoro-2-butyl
H
Cl


7-105
phenyl
Me
H
H
H
H
H
F
H
nonafluoro-2-butyl
H
Br


7-106
phenyl
Me
H
H
H
H
H
F
H
nonafluoro-2-butyl
H
I


7-107
phenyl
Me
H
H
H
H
H
Cl
H
nonafluoro-2-butyl
H
Br


7-108
phenyl
Me
H
H
H
H
H
Cl
H
nonafluoro-2-butyl
H
I


7-109
phenyl
Me
H
H
H
H
H
Br
H
nonafluoro-2-butyl
H
I


7-110
phenyl
Me
H
H
H
H
H
F
H
heptafluoroisopropyl
H
CF3


7-111
phenyl
Me
H
H
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


7-131
3-cyanophenyl
Me
H
H
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


7-132
4-cyanophenyl
Me
H
H
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


7-147
2-chloropyridin-3-yl
Me
H
H
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


7-189
phenyl
Me
H
H
H
H
H
F
H
nonafluoro-2-butyl
H
CF3


7-190
phenyl
Me
H
H
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


7-210
3-cyanophenyl
Me
H
H
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


7-211
4-cyanophenyl
Me
H
H
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


7-226
2-chloropyridin-3-yl
Me
H
H
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


7-268
phenyl
Me
H
H
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-269
2-fluorophenyl
Me
H
H
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-270
3-fluorophenyl
Me
H
H
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-271
4-fluorophenyl
Me
H
H
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-285
3-nitrophenyl
Me
H
H
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-286
4-nitrophenyl
Me
H
H
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-288
3-cyanophenyl
Me
H
H
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-289
4-cyanophenyl
Me
H
H
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-290
2,6-difluorophenyl
Me
H
H
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-299
3,5-dicyanophenyl
Me
H
H
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-300
4-cyano-2-fluorophenyl
Me
H
H
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-301
2-chloro-4-cyanophenyl
Me
H
H
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-303
2-fluoropyridin-3-yl
Me
H
H
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-304
2-chloropyridin-3-yl
Me
H
H
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-305
2-bromopyridin-3-yl
Me
H
H
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-311
6-chloropyridin-3-yl
Me
H
H
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-316
6-cyanopyridin-3-yl
Me
H
H
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-346
phenyl
Me
H
H
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-347
2-fluorophenyl
Me
H
H
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-348
3-fluorophenyl
Me
H
H
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-349
4-fluorophenyl
Me
H
H
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-366
3-cyanophenyl
Me
H
H
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-367
4-cyanophenyl
Me
H
H
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-368
2,6-difluorophenyl
Me
H
H
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-382
2-chloropyridin-3-yl
Me
H
H
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-389
6-chloropyridin-3-yl
Me
H
H
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-424
phenyl
Me
H
H
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-425
2-fluorophenyl
Me
H
H
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-426
3-fluorophenyl
Me
H
H
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-427
4-fluorophenyl
Me
H
H
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-428
2-chlorophenyl
Me
H
H
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-444
3-cyanophenyl
Me
H
H
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-445
4-cyanophenyl
Me
H
H
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-446
2,6-difluorophenyl
Me
H
H
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-449
2-chloro-4-fluorophenyl
Me
H
H
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-460
2-chloropyridin-3-yl
Me
H
H
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-467
6-chloropyridin-3-yl
Me
H
H
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-502
phenyl
Me
H
H
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-504
3-fluorophenyl
Me
H
H
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-505
4-fluorophenyl
Me
H
H
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-522
3-cyanophenyl
Me
H
H
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-523
4-cyanophenyl
Me
H
H
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-538
2-chloropyridin-3-yl
Me
H
H
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-580
phenyl
Me
H
H
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


7-611
2-chloropyridin-3-yl
Me
H
H
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


7-636
phenyl
Me
H
H
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


7-667
2-chloropyridin-3-yl
Me
H
H
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


7-692
phenyl
Me
H
H
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


7-723
2-chloropyridin-3-yl
Me
H
H
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


7-748
phenyl
Me
H
H
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


7-779
2-chloropyridin-3-yl
Me
H
H
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


7-804
phenyl
Me
H
H
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


7-824
3-cyanophenyl
Me
H
H
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


7-825
4-cyanophenyl
Me
H
H
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


7-840
2-chloropyridin-3-yl
Me
H
H
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


7-841
2-bromopyridin-3-yl
Me
H
H
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


7-872
phenyl
Me
H
H
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


7-892
3-cyanophenyl
Me
H
H
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


7-893
4-cyanophenyl
Me
H
H
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


7-908
2-chloropyridin-3-yl
Me
H
H
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


7-940
phenyl
Me
H
F
H
H
H
F
H
heptafluoroisopropyl
H
F


7-941
3-cyanophenyl
Me
H
F
H
H
H
F
H
heptafluoroisopropyl
H
F


7-942
4-cyanophenyl
Me
H
F
H
H
H
F
H
heptafluoroisopropyl
H
F


7-943
2-chloropyridin-3-yl
Me
H
F
H
H
H
F
H
heptafluoroisopropyl
H
F


7-944
phenyl
Me
H
F
H
H
H
F
H
nonafluoro-2-butyl
H
F


7-945
3-cyanophenyl
Me
H
F
H
H
H
F
H
nonafluoro-2-butyl
H
F


7-946
4-cyanophenyl
Me
H
F
H
H
H
F
H
nonafluoro-2-butyl
H
F


7-947
2-chloropyridin-3-yl
Me
H
F
H
H
H
F
H
nonafluoro-2-butyl
H
F


7-948
phenyl
Me
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


7-968
3-cyanophenyl
Me
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


7-969
4-cyanophenyl
Me
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


7-984
2-chloropyridin-3-yl
Me
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


7-1026
phenyl
Me
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


7-1046
3-cyanophenyl
Me
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


7-1047
4-cyanophenyl
Me
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


7-1062
2-chloropyridin-3-yl
Me
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


7-1104
phenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
Br


7-1105
2-fluorophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
Br


7-1106
3-fluorophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
Br


7-1107
4-fluorophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
Br


7-1124
3-cyanophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
Br


7-1125
4-cyanophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
Br


7-1126
2,6-difluorophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
Br


7-1140
2-chloropyridin-3-yl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
Br


7-1147
6-chloropyridin-3-yl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
Br


7-1182
phenyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


7-1183
2-fluorophenyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


7-1184
3-fluorophenyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


7-1185
4-fluorophenyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


7-1202
3-cyanophenyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


7-1203
4-cyanophenyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


7-1204
2,6-difluorophenyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


7-1218
2-chloropyridin-3-yl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


7-1225
6-chloropyridin-3-yl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


7-1260
phenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
I


7-1261
2-fluorophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
I


7-1262
3-fluorophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
I


7-1263
4-fluorophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
I


7-1280
3-cyanophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
I


7-1281
4-cyanophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
I


7-1282
2,6-difluorophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
I


7-1296
2-chloropyridin-3-yl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
I


7-1303
6-chloropyridin-3-yl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
I


7-1338
phenyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
I


7-1339
2-fluorophenyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
I


7-1340
3-fluorophenyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
I


7-1341
4-fluorophenyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
I


7-1358
3-cyanophenyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
I


7-1359
4-cyanophenyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
I


7-1360
2,6-difluorophenyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
I


7-1374
2-chloropyridin-3-yl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
I


7-1381
6-chloropyridin-3-yl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
I


7-1416
phenyl
Me
H
F
H
H
H
F
H
heptafluoroisopropyl
H
CF3


7-1417
phenyl
Me
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


7-1428
3-iodophenyl
Me
H
F
H
H
H
Cl
H
pentafluoroethyl
H
CF3


7-1429
4-iodophenyl
Me
H
F
H
H
H
Cl
H
pentafluoroethyl
H
CF3


7-1431
(3-trifluoromethyl)phenyl
Et
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


7-1436
2-cyanophenyl
Me
H
F
H
H
H
Cl
H
pentafluoroethyl
H
C2F5


7-1437
3-cyanophenyl
Me
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


7-1438
4-cyanophenyl
Me
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


7-1441
2,4-dichlorophenyl
Me
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
C2F5


7-1442
2-chloro-4-fluorophenyl
n-Pr
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


7-1445
2-bromo-4-chlorophenyl
Me
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


7-1452
2-fluoropyridin-3-yl
Me
H
F
H
H
H
Cl
H
pentafluoroethyl
H
CF3


7-1453
2-chloropyridin-3-yl
Me
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


7-1459
6-fluoropyridin-3-yl
i-Pr
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


7-1466
5-fluoropyridin-3-yl
Me
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
C2F5


7-1468
5-bromopyridin-3-yl
Me
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


7-1469
5-iodopyridin-3-yl
Me
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
i-C3F7


7-1471
5-nitropyridin-3-yl
Me
H
F
H
H
H
Cl
H
pentafluoroethyl
H
CF3


7-1473
4-fluoropyridin-3-yl
Me
H
F
H
H
H
Cl
H
pentafluoroethyl
H
CF3


7-1475
4-bromopyridin-3-yl
CH2CH═CH2
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


7-1476
4-iodopyridin-3-yl
Me
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
i-C3F7


7-1482
pyridin-4-yl
CN
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


7-1494
4-cyanopyridin-2-yl
Me
H
F
H
H
H
Cl
H
pentafluoroethyl
H
CF3


7-1495
phenyl
Me
H
F
H
H
H
F
H
nonafluoro-2-butyl
H
CF3


7-1496
phenyl
Me
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


7-1504
3-bromophenyl
CH2C≡CH
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


7-1509
(2-trifluoromethyl)phenyl
Me
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


7-1511
(4-trifluoromethyl)phenyl
NH2
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


7-1516
3-cyanophenyl
Me
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


7-1517
4-cyanophenyl
Me
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


7-1524
2-bromo-4-chlorophenyl
C(O)OMe
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


7-1526
2-chloro-4-nitrophenyl
Me
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


7-1532
2-chloropyridin-3-yl
Me
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


7-1545
5-fluoropyridin-3-yl
C(O)OEt
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


7-1547
5-bromopyridin-3-yl
Me
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
n-C3F7


7-1548
5-iodopyridin-3-yl
Me
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


7-1552
4-fluoropyridin-3-yl
Me
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


7-1554
4-bromopyridin-3-yl
C(O)C(O)Me
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


7-1556
4-(trifluoromethyl)pyridin-3-yl
Me
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
n-C3F7


7-1557
4-nitropyridin-3-yl
C(O)C(O)Et
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


7-1571
5-iodopyridin-2-yl
C(O)Me
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


7-1573
4-cyanopyridin-2-yl
C(O)Et
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


7-1574
phenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1575
2-fluorophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1576
3-fluorophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1577
4-fluorophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1578
2-chlorophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1579
3-chlorophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1580
4-chlorophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1581
2-bromophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1582
3-bromophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1583
4-bromophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1584
2-iodophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1585
3-iodophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1586
4-iodophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1587
(2-trifluoromethyl)phenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1588
(3-trifluoromethyl)phenyl
S(O)2Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1589
(4-trifluoromethyl)phenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1590
2-nitrophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1591
3-nitrophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1592
4-nitrophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1593
2-cyanophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1594
3-cyanophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1595
4-cyanophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1596
2,6-difluorophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1597
3,4-dichlorophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1598
2,4-dichlorophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1599
2-chloro-4-fluorophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1600
2-chloro-4,5-difluorophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1601
4-bromo-2-chlorophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1602
2-bromo-4-chlorophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1603
2-bromo-4-fluorophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1604
2-chloro-4-nitrophenyl
S(O)2Et
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1605
3,5-dicyanophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1606
4-cyano-2-fluorophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1607
2-chloro-4-cyanophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1608
pyridin-3-yl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1609
2-fluoropyridin-3-yl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1610
2-chloropyridin-3-yl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1611
2-bromopyridin-3-yl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1612
2-iodopyridin-3-yl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1613
2-(trifluoromethyl)pyridin-3-yl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1614
2-nitropyridin-3-yl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1615
2-cyanopyridin-3-yl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1616
6-fluoropyridin-3-yl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1617
6-chloropyridin-3-yl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1618
6-bromopyridin-3-yl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1619
6-iodopyridin-3-yl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1620
6-(trifluoromethyl)pyridin-3-yl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1621
6-nitropyridin-3-yl
CH2Ph
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1622
6-cyanopyridin-3-yl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1623
5-fluoropyridin-3-yl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1624
5-chloropyridin-3-yl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1625
5-bromopyridin-3-yl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1626
5-iodopyridin-3-yl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1627
5-(trifluoromethyl)pyridin-3-yl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1628
5-nitropyridin-3-yl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1629
5-cyanopyridin-3-yl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1630
4-fluoropyridin-3-yl
CH2(3-Py)
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1631
4-chloropyridin-3-yl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1632
4-bromopyridin-3-yl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1633
4-iodopyridin-3-yl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1634
4-(trifluoromethyl)pyridin-3-yl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1635
4-nitropyridin-3-yl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1636
4-cyanopyridin-3-yl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1637
2,6-dichloropyridin-3-yl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1638
pyridin-3-yl N-oxide
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1639
pyridin-4-yl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1640
2-chloropyridin-4-yl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1641
3-bromopyridin-4-yl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1642
3,5-dichloropyridin-4-yl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1643
3-(trifluoromethyl)pyridin-4-yl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1644
2,6-dicyanopyridin-4-yl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1645
pyridin-4-yl N-oxide
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1646
pyridin-2-yl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1647
3-chloropyridin-2-yl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1648
4-bromopyridin-2-yl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1649
5-iodopyridin-2-yl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1650
6-chloropyridin-2-yl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1651
4-cyanopyridin-2-yl
CH2(3-Py—N-
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3




oxide)


7-1652
phenyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1653
2-fluorophenyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1654
3-fluorophenyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1655
4-fluorophenyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1656
2-chlorophenyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1657
3-chlorophenyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1658
4-chlorophenyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1659
2-bromophenyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1660
3-bromophenyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1661
4-bromophenyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1662
2-iodophenyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1663
3-iodophenyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1664
4-iodophenyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1665
(2-trifluoromethyl)phenyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1666
(3-trifluoromethyl)phenyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1667
(4-trifluoromethyl)phenyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1668
2-nitrophenyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1669
3-nitrophenyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1670
4-nitrophenyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1671
2-cyanophenyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1672
3-cyanophenyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1673
4-cyanophenyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1674
2,6-difluorophenyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1675
3,4-dichlorophenyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1676
2,4-dichlorophenyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1677
2-chloro-4-fluorophenyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1678
2-chloro-4,5-difluorophenyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1679
4-bromo-2-chlorophenyl
Et
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1680
2-bromo-4-chlorophenyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1681
2-bromo-4-fluorophenyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1682
2-chloro-4-nitrophenyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1683
3,5-dicyanophenyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1684
4-cyano-2-fluorophenyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1685
2-chloro-4-cyanophenyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1686
pyridin-3-yl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1687
2-fluoropyridin-3-yl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1688
2-chloropyridin-3-yl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1689
2-bromopyridin-3-yl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1690
2-iodopyridin-3-yl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1691
2-(trifluoromethyl)pyridin-3-yl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1692
2-nitropyridin-3-yl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1693
2-cyanopyridin-3-yl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1694
6-fluoropyridin-3-yl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1695
6-chloropyridin-3-yl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1696
6-bromopyridin-3-yl
Me
H
F
H
H
H
Br
H
nanafluoro-2-butyl
H
CF3


7-1697
6-iodopyridin-3-yl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1698
6-(trifluoromethyl)pyridin-3-yl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1699
6-nitropyridin-3-yl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1700
6-cyanopyridin-3-yl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1701
5-fluoropyridin-3-yl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1702
5-chloropyridin-3-yl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1703
5-bromopyridin-3-yl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1704
5-iodopyridin-3-yl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1705
5-(trifluoromethyl)pyridin-3-yl
CN
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1706
5-nitropyridin-3-yl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1707
5-cyanopyridin-3-yl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1708
4-fluoropyridin-3-yl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1709
4-chloropyridin-3-yl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1710
4-bromopyridin-3-yl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1711
4-iodopyridin-3-yl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1712
4-(trifluoromethyl)pyridin-3-yl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1713
4-nitropyridin-3-yl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1714
4-cyanopyridin-3-yl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1715
2,6-dichloropyridin-3-yl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1716
pyridin-3-yl N-oxide
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1717
pyridin-4-yl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1718
2-chloropyridin-4-yl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1719
3-bromopyridin-4-yl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1720
3,5-dichloropyridin-4-yl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1721
3-(trifluoromethyl)pyridin-4-yl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1722
2,6-dicyanopyridin-4-yl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1723
pyridin-4-yl N-oxide
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1724
pyridin-2-yl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1725
3-chloropyridin-2-yl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1726
4-bromopyridin-2-yl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1727
5-iodopyridin-2-yl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1728
6-chloropyridin-2-yl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1729
4-cyanopyridin-2-yl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-1730
phenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1731
2-fluorophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1732
3-fluorophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1733
4-fluorophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1734
2-chlorophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1735
3-chlorophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1736
4-chlorophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1737
2-bromophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1738
3-bromophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1739
4-bromophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1740
2-iodophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1741
3-iodophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1742
4-iodophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1743
(2-trifluoromethyl)phenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1744
(3-trifluoromethyl)phenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1745
(4-trifluoromethyl)phenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1746
2-nitrophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1747
3-nitrophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1748
4-nitrophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1749
2-cyanophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1750
3-cyanophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1751
4-cyanophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1752
2,6-difluorophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1753
3,4-dichlorophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1754
2,4-dichlorophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1755
2-chloro-4-fluorophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1756
2-chloro-4,5-difluorophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1757
4-bromo-2-chlorophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1758
2-bromo-4-chlorophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1759
2-bromo-4-fluorophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1760
2-chloro-4-nitrophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1761
3,5-dicyanophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1762
4-cyano-2-fluorophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1763
2-chloro-4-cyanophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1764
pyridin-3-yl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1765
2-fluoropyridin-3-yl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1766
2-chloropyridin-3-yl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1767
2-bromopyridin-3-yl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1768
2-iodopyridin-3-yl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1769
2-(trifluoromethyl)pyridin-3-yl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1770
2-nitropyridin-3-yl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1771
2-cyanopyridin-3-yl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1772
6-fluoropyridin-3-yl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1773
6-chloropyridin-3-yl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1774
6-bromopyridin-3-yl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1775
6-iodopyridin-3-yl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1776
6-(trifluoromethyl)pyridin-3-yl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1777
6-nitropyridin-3-yl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1778
6-cyanopyridin-3-yl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1779
5-fluoropyridin-3-yl
C(O)Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1780
5-chloropyridin-3-yl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1781
5-bromopyridin-3-yl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1782
5-iodopyridin-3-yl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1783
5-(trifluoromethyl)pyridin-3-yl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1784
5-nitropyridin-3-yl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1785
5-cyanopyridin-3-yl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1786
4-fluoropyridin-3-yl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1787
4-chloropyridin-3-yl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1788
4-bromopyridin-3-yl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1789
4-iodopyridin-3-yl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1790
4-(trifluoromethyl)pyridin-3-yl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1791
4-nitropyridin-3-yl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1792
4-cyanopyridin-3-yl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1793
2,6-dichloropyridin-3-yl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1794
pyridin-3-yl N-oxide
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1795
pyridin-4-yl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1796
2-chloropyridin-4-yl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1797
3-bromopyridin-4-yl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1798
3,5-dichloropyridin-4-yl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1799
3-(trifluoromethyl)pyridin-4-yl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1800
2,6-dicyanopyridin-4-yl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1801
pyridin-4-yl N-oxide
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1802
pyridin-2-yl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1803
3-chloropyridin-2-yl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1804
4-bromopyridin-2-yl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1805
5-iodopyridin-2-yl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1806
6-chloropyridin-2-yl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1807
4-cyanopyridin-2-yl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1808
phenyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1809
2-fluorophenyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1810
3-fluorophenyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1811
4-fluorophenyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1812
2-chlorophenyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1813
3-chlorophenyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1814
4-chlorophenyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1815
2-bromophenyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1816
3-bromophenyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1817
4-bromophenyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1818
2-iodophenyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1819
3-iodophenyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1820
4-iodophenyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1821
(2-trifluoromethyl)phenyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1822
(3-trifluoromethyl)phenyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1823
(4-trifluoromethyl)phenyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1824
2-nitrophenyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1825
3-nitrophenyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1826
4-nitrophenyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1827
2-cyanophenyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1828
3-cyanophenyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1829
4-cyanophenyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1830
2,6-difluorophenyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1831
3,4-dichlorophenyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1832
2,4-dichlorophenyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1833
2-chloro-4-fluorophenyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1834
2-chloro-4,5-difluorophenyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1835
4-bromo-2-chlorophenyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1836
2-bromo-4-chlorophenyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1837
2-bromo-4-fluorophenyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1838
2-chloro-4-nitrophenyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1839
3,5-dicyanophenyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1840
4-cyano-2-fluorophenyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1841
2-chloro-4-cyanophenyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1842
pyridin-3-yl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1843
2-fluoropyridin-3-yl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1844
2-chloropyridin-3-yl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1845
2-bromopyridin-3-yl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1846
2-iodopyridin-3-yl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1847
2-(trifluoromethyl)pyridin-3-yl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1848
2-nitropyridin-3-yl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1849
2-cyanopyridin-3-yl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1850
6-fluoropyridin-3-yl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1851
6-chloropyridin-3-yl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1852
6-bromopyridin-3-yl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1853
6-iodopyridin-3-yl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1854
6-(trifluoromethyl)pyridin-3-yl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1855
6-nitropyridin-3-yl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1856
6-cyanopyridin-3-yl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1857
5-fluoropyridin-3-yl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1858
5-chloropyridin-3-yl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1859
5-bromopyridin-3-yl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1860
5-iodopyridin-3-yl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1861
5-(trifluoromethyl)pyridin-3-yl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1862
5-nitropyridin-3-yl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1863
5-cyanopyridin-3-yl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1864
4-fluoropyridin-3-yl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1865
4-chloropyridin-3-yl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1866
4-bromopyridin-3-yl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1867
4-iodopyridin-3-yl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1868
4-(trifluoromethyl)pyridin-3-yl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1869
4-nitropyridin-3-yl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1870
4-cyanopyridin-3-yl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1871
2,6-dichloropyridin-3-yl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1872
pyridin-3-yl N-oxide
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1873
pyridin-4-yl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1874
2-chloropyridin-4-yl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1875
3-bromopyridin-4-yl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1876
3,5-dichloropyridin-4-yl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1877
3-(trifluoromethyl)pyridin-4-yl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1878
2,6-dicyanopyridin-4-yl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1879
pyridin-4-yl N-oxide
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1880
pyridin-2-yl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1881
3-chloropyridin-2-yl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1882
4-bromopyridin-2-yl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1883
5-iodopyridin-2-yl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1884
6-chloropyridin-2-yl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1885
4-cyanopyridin-2-yl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-1886
phenyl
Me
H
F
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


7-1901
3-cyanophenyl
Me
H
F
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


7-1902
4-cyanophenyl
Me
H
F
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


7-1917
2-chloropyridin-3-yl
Me
H
F
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


7-1942
phenyl
Me
H
F
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


7-1957
3-cyanophenyl
Me
H
F
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


7-1958
4-cyanophenyl
Me
H
F
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


7-1973
2-chloropyridin-3-yl
Me
H
F
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


7-1998
phenyl
Me
H
F
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


7-2013
3-cyanophenyl
Me
H
F
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


7-2014
4-cyanophenyl
Me
H
F
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


7-2029
2-chloropyridin-3-yl
Me
H
F
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


7-2054
phenyl
Me
H
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


7-2069
3-cyanophenyl
Me
H
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


7-2070
4-cyanophenyl
Me
H
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


7-2085
2-chloropyridin-3-yl
Me
H
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


7-2110
phenyl
Me
H
F
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


7-2130
3-cyanophenyl
Me
H
F
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


7-2131
4-cyanophenyl
Me
H
F
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


7-2146
2-chloropyridin-3-yl
Me
H
F
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


7-2178
phenyl
Me
H
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


7-2198
3-cyanophenyl
Me
H
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


7-2199
4-cyanophenyl
Me
H
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


7-2214
2-chloropyridin-3-yl
Me
H
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


7-2246
phenyl
Me
H
H
F
H
H
F
H
heptafluoroisopropyl
H
F


7-2247
3-cyanophenyl
Me
H
H
F
H
H
F
H
heptafluoroisopropyl
H
F


7-2248
4-cyanophenyl
Me
H
H
F
H
H
F
H
heptafluoroisopropyl
H
F


7-2249
2-chloropyridin-3-yl
Me
H
H
F
H
H
F
H
heptafluoroisopropyl
H
F


7-2250
phenyl
Me
H
H
F
H
H
F
H
nonafluoro-2-butyl
H
F


7-2251
3-cyanophenyl
Me
H
H
F
H
H
F
H
nonafluoro-2-butyl
H
F


7-2252
4-cyanophenyl
Me
H
H
F
H
H
F
H
nonafluoro-2-butyl
H
F


7-2253
2-chloropyridin-3-yl
Me
H
H
F
H
H
F
H
nonafluoro-2-butyl
H
F


7-2254
phenyl
Me
H
H
F
H
H
Cl
H
heptafluoroisopropyl
H
Cl


7-2274
3-cyanophenyl
Me
H
H
F
H
H
Cl
H
heptafluoroisopropyl
H
Cl


7-2275
4-cyanophenyl
Me
H
H
F
H
H
Cl
H
heptafluoroisopropyl
H
Cl


7-2290
2-chloropyridin-3-yl
Me
H
H
F
H
H
Cl
H
heptafluoroisopropyl
H
Cl


7-2332
phenyl
Me
H
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


7-2352
3-cyanophenyl
Me
H
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


7-2353
4-cyanophenyl
Me
H
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


7-2368
2-chloropyridin-3-yl
Me
H
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


7-2410
phenyl
Me
H
H
F
H
H
Br
H
heptafluoroisopropyl
H
Br


7-2430
3-cyanophenyl
Me
H
H
F
H
H
Br
H
heptafluoroisopropyl
H
Br


7-2431
4-cyanophenyl
Me
H
H
F
H
H
Br
H
heptafluoroisopropyl
H
Br


7-2446
2-chloropyridin-3-yl
Me
H
H
F
H
H
Br
H
heptafluoroisopropyl
H
Br


7-2488
phenyl
Me
H
H
F
H
H
Br
H
nonafluoro-2-butyl
H
Br


7-2508
3-cyanophenyl
Me
H
H
F
H
H
Br
H
nonafluoro-2-butyl
H
Br


7-2509
4-cyanophenyl
Me
H
H
F
H
H
Br
H
nonafluoro-2-butyl
H
Br


7-2524
2-chloropyridin-3-yl
Me
H
H
F
H
H
Br
H
nonafluoro-2-butyl
H
Br


7-2566
phenyl
Me
H
H
F
H
H
I
H
heptafluoroisopropyl
H
I


7-2586
3-cyanophenyl
Me
H
H
F
H
H
I
H
heptafluoroisopropyl
H
I


7-2587
4-cyanophenyl
Me
H
H
F
H
H
I
H
heptafluoroisopropyl
H
I


7-2602
2-chloropyridin-3-yl
Me
H
H
F
H
H
I
H
heptafluoroisopropyl
H
I


7-2644
phenyl
Me
H
H
F
H
H
I
H
nonafluoro-2-butyl
H
I


7-2664
3-cyanophenyl
Me
H
H
F
H
H
I
H
nonafluoro-2-butyl
H
I


7-2665
4-cyanophenyl
Me
H
H
F
H
H
I
H
nonafluoro-2-butyl
H
I


7-2680
2-chloropyridin-3-yl
Me
H
H
F
H
H
I
H
nonafluoro-2-butyl
H
I


7-2722
phenyl
Me
H
H
F
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


7-2742
3-cyanophenyl
Me
H
H
F
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


7-2743
4-cyanophenyl
Me
H
H
F
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


7-2758
2-chloropyridin-3-yl
Me
H
H
F
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


7-2800
phenyl
Me
H
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


7-2820
3-cyanophenyl
Me
H
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


7-2821
4-cyanophenyl
Me
H
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


7-2836
2-chloropyridin-3-yl
Me
H
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


7-2878
phenyl
Me
H
H
F
H
H
Br
H
heptafluoroisopropyl
H
OCF3


7-2898
3-cyanophenyl
Me
H
H
F
H
H
Br
H
heptafluoroisopropyl
H
OCF3


7-2899
4-cyanophenyl
Me
H
H
F
H
H
Br
H
heptafluoroisopropyl
H
OCF3


7-2914
2-chloropyridin-3-yl
Me
H
H
F
H
H
Br
H
heptafluoroisopropyl
H
OCF3


7-2956
phenyl
Me
H
H
F
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


7-2976
3-cyanophenyl
Me
H
H
F
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


7-2977
4-cyanophenyl
Me
H
H
F
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


7-2992
2-chloropyridin-3-yl
Me
H
H
F
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


7-3034
phenyl
Me
H
H
F
H
H
I
H
heptafluoroisopropyl
H
OCF3


7-3054
3-cyanophenyl
Me
H
H
F
H
H
I
H
heptafluoroisopropyl
H
OCF3


7-3055
4-cyanophenyl
Me
H
H
F
H
H
I
H
heptafluoroisopropyl
H
OCF3


7-3070
2-chloropyridin-3-yl
Me
H
H
F
H
H
I
H
heptafluoroisopropyl
H
OCF3


7-3112
phenyl
Me
H
H
F
H
H
I
H
nonafluoro-2-butyl
H
OCF3


7-3132
3-cyanophenyl
Me
H
H
F
H
H
I
H
nonafluoro-2-butyl
H
OCF3


7-3133
4-cyanophenyl
Me
H
H
F
H
H
I
H
nonafluoro-2-butyl
H
OCF3


7-3148
2-chloropyridin-3-yl
Me
H
H
F
H
H
I
H
nonafluoro-2-butyl
H
OCF3


7-3190
phenyl
Me
H
H
F
H
H
F
H
heptafluoroisopropyl
H
CF3


7-3191
phenyl
Me
H
H
F
H
H
Cl
H
heptafluoroisopropyl
H
CF3


7-3211
3-cyanophenyl
Me
H
H
F
H
H
Cl
H
heptafluoroisopropyl
H
CF3


7-3212
4-cyanophenyl
Me
H
H
F
H
H
Cl
H
heptafluoroisopropyl
H
CF3


7-3227
2-chloropyridin-3-yl
Me
H
H
F
H
H
Cl
H
heptafluoroisopropyl
H
CF3


7-3269
phenyl
Me
H
H
F
H
H
F
H
nonafluoro-2-butyl
H
CF3


7-3270
phenyl
Me
H
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


7-3290
3-cyanophenyl
Me
H
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


7-3291
4-cyanophenyl
Me
H
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


7-3306
2-chloropyridin-3-yl
Me
H
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


7-3348
phenyl
Me
H
H
F
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-3368
3-cyanophenyl
Me
H
H
F
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-3369
4-cyanophenyl
Me
H
H
F
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-3384
2-chloropyridin-3-yl
Me
H
H
F
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-3426
phenyl
Me
H
H
F
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-3446
3-cyanophenyl
Me
H
H
F
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-3447
4-cyanophenyl
Me
H
H
F
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-3462
2-chloropyridin-3-yl
Me
H
H
F
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-3504
phenyl
Me
H
H
F
H
H
I
H
heptafluoroisopropyl
H
CF3


7-3524
3-cyanophenyl
Me
H
H
F
H
H
I
H
heptafluoroisopropyl
H
CF3


7-3525
4-cyanophenyl
Me
H
H
F
H
H
I
H
heptafluoroisopropyl
H
CF3


7-3582
phenyl
Me
H
H
F
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-3602
3-cyanophenyl
Me
H
H
F
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-3603
4-cyanophenyl
Me
H
H
F
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-3618
2-chloropyridin-3-yl
Me
H
H
F
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-3660
phenyl
Me
H
H
F
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


7-3691
2-chloropyridin-3-yl
Me
H
H
F
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


7-3716
phenyl
Me
H
H
F
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


7-3747
2-chloropyrtdin-3-yl
Me
H
H
F
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


7-3772
phenyl
Me
H
H
F
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


7-3803
2-chloropyridin-3-yl
Me
H
H
F
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


7-3828
phenyl
Me
H
H
F
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


7-3859
2-chloropyridin-3-yl
Me
H
H
F
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


7-3884
phenyl
Me
H
H
F
H
H
CF3
H
heptafluoroisopropyl
H
CF3


7-3904
3-cyanophenyl
Me
H
H
F
H
H
CF3
H
heptafluoroisopropyl
H
CF3


7-3905
4-cyanophenyl
Me
H
H
F
H
H
CF3
H
heptafluoroisopropyl
H
CF3


7-3920
2-chloropyridin-3-yl
Me
H
H
F
H
H
CF3
H
heptafluoroisopropyl
H
CF3


7-3952
phenyl
Me
H
H
F
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


7-3972
3-cyanophenyl
Me
H
H
F
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


7-3973
4-cyanophenyl
Me
H
H
F
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


7-3988
2-chloropyridin-3-yl
Me
H
H
F
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


7-4020
phenyl
Me
H
F
F
H
H
F
H
heptafluoroisopropyl
H
F


7-4021
3-cyanophenyl
Me
H
F
F
H
H
F
H
heptafluoroisopropyl
H
F


7-4022
4-cyanophenyl
Me
H
F
F
H
H
F
H
heptafluoroisopropyl
H
F


7-4023
2-chloropyridin-3-yl
Me
H
F
F
H
H
F
H
heptafluoroisopropyl
H
F


7-4024
phenyl
Me
H
F
F
H
H
F
H
nonafluoro-2-butyl
H
F


7-4025
3-cyanophenyl
Me
H
F
F
H
H
F
H
nonafluoro-2-butyl
H
F


7-4026
4-cyanophenyl
Me
H
F
F
H
H
F
H
nonafluoro-2-butyl
H
F


7-4027
2-chloropyridin-3-yl
Me
H
F
F
H
H
F
H
nonafluoro-2-butyl
H
F


7-4028
phenyl
Me
H
F
F
H
H
Cl
H
heptafluoroisopropyl
H
Cl


7-4048
3-cyanophenyl
Me
H
F
F
H
H
Cl
H
heptafluoroisopropyl
H
Cl


7-4049
4-cyanophenyl
Me
H
F
F
H
H
Cl
H
heptafluoroisopropyl
H
Cl


7-4064
2-chloropyridin-3-yl
Me
H
F
F
H
H
Cl
H
heptafluoroisopropyl
H
Cl


7-4106
phenyl
Me
H
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


7-4126
3-cyanophenyl
Me
H
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


7-4127
4-cyanophenyl
Me
H
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


7-4142
2-chloropyridin-3-yl
Me
H
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


7-4184
phenyl
Me
H
F
F
H
H
Br
H
heptafluoroisopropyl
H
Br


7-4204
3-cyanophenyl
Me
H
F
F
H
H
Br
H
heptafluoroisopropyl
H
Br


7-4205
4-cyanophenyl
Me
H
F
F
H
H
Br
H
heptafluoroisopropyl
H
Br


7-4220
2-chloropyridin-3-yl
Me
H
F
F
H
H
Br
H
heptafluoroisopropyl
H
Br


7-4262
phenyl
Me
H
F
F
H
H
Br
H
nonafluoro-2-butyl
H
Br


7-4282
3-cyanophenyl
Me
H
F
F
H
H
Br
H
nonafluoro-2-butyl
H
Br


7-4283
4-cyanophenyl
Me
H
F
F
H
H
Br
H
nonafluoro-2-butyl
H
Br


7-4298
2-chloropyridin-3-yl
Me
H
F
F
H
H
Br
H
nonafluoro-2-butyl
H
Br


7-4340
phenyl
Me
H
F
F
H
H
I
H
heptafluoroisopropyl
H
I


7-4360
3-cyanophenyl
Me
H
F
F
H
H
I
H
heptafluoroisopropyl
H
I


7-4361
4-cyanophenyl
Me
H
F
F
H
H
I
H
heptafluoroisopropyl
H
I


7-4376
2-chloropyridin-3-yl
Me
H
F
F
H
H
I
H
heptafluoroisopropyl
H
I


7-4418
phenyl
Me
H
F
F
H
H
I
H
nonafluoro-2-butyl
H
I


7-4438
3-cyanophenyl
Me
H
F
F
H
H
I
H
nonafluoro-2-butyl
H
I


7-4439
4-cyanophenyl
Me
H
F
F
H
H
I
H
nonafluoro-2-butyl
H
I


7-4454
2-chloropyridin-3-yl
Me
H
F
F
H
H
I
H
nonafluoro-2-butyl
H
I


7-4496
phenyl
Me
H
F
F
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


7-4516
3-cyanophenyl
Me
H
F
F
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


7-4517
4-cyanophenyl
Me
H
F
F
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


7-4532
2-chloropyridin-3-yl
Me
H
F
F
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


7-4574
phenyl
Me
H
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


7-4594
3-cyanophenyl
Me
H
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


7-4595
4-cyanophenyl
Me
H
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


7-4610
2-chloropyridin-3-yl
Me
H
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


7-4652
phenyl
Me
H
F
F
H
H
Br
H
heptafluoroisopropyl
H
OCF3


7-4672
3-cyanophenyl
Me
H
F
F
H
H
Br
H
heptafluoroisopropyl
H
OCF3


7-4673
4-cyanophenyl
Me
H
F
F
H
H
Br
H
heptafluoroisopropyl
H
OCF3


7-4688
2-chloropyridin-3-yl
Me
H
F
F
H
H
Br
H
heptafluoroisopropyl
H
OCF3


7-4730
phenyl
Me
H
F
F
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


7-4750
3-cyanophenyl
Me
H
F
F
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


7-4751
4-cyanophenyl
Me
H
F
F
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


7-4766
2-chloropyridin-3-yl
Me
H
F
F
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


7-4808
phenyl
Me
H
F
F
H
H
I
H
heptafluoroisopropyl
H
OCF3


7-4828
3-cyanophenyl
Me
H
F
F
H
H
I
H
heptafluoroisopropyl
H
OCF3


7-4829
4-cyanophenyl
Me
H
F
F
H
H
I
H
heptafluoroisopropyl
H
OCF3


7-4844
2-chloropyridin-3-yl
Me
H
F
F
H
H
I
H
heptafluoroisopropyl
H
OCF3


7-4886
phenyl
Me
H
F
F
H
H
I
H
nonafluoro-2-butyl
H
OCF3


7-4906
3-cyanophenyl
Me
H
F
F
H
H
I
H
nonafluoro-2-butyl
H
OCF3


7-4907
4-cyanophenyl
Me
H
F
F
H
H
I
H
nonafluoro-2-butyl
H
OCF3


7-4922
2-chloropyridin-3-yl
Me
H
F
F
H
H
I
H
nonafluoro-2-butyl
H
OCF3


7-4964
phenyl
Me
H
F
F
H
H
F
H
heptafluoroisopropyl
H
CF3


7-4965
phenyl
Me
H
F
F
H
H
Cl
H
heptafluoroisoproplyl
H
CF3


7-4985
3-cyanophenyl
Me
H
F
F
H
H
Cl
H
heptafluoroisoprppyl
H
CF3


7-4986
4-cyanophenyl
Me
H
F
F
H
H
Cl
H
heptafluoroisopropyl
H
CF3


7-5001
2-chloropyridin-3-yl
Me
H
F
F
H
H
Cl
H
heptafluoroisopropyl
H
CF3


7-5043
phenyl
Me
H
F
F
H
H
F
H
nonafluoro-2-butyl
H
CF3


7-5044
phenyl
Me
H
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


7-5064
3-cyanophenyl
Me
H
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


7-5065
4-cyanophenyl
Me
H
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


7-5080
2-chloropyridin-3-yl
Me
H
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


7-5122
phenyl
Me
H
F
F
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-5142
3-cyanophenyl
Me
H
F
F
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-5143
4-cyanophenyl
Me
H
F
F
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-5158
2-chloropyridin-3-yl
Me
H
F
F
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-5200
phenyl
Me
H
F
F
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-5220
3-cyanophenyl
Me
H
F
F
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-5221
4-cyanophenyl
Me
H
F
F
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-5236
2-chloropyridin-3-yl
Me
H
F
F
H
H
Br
H
nonafluoro-2-butyl
H
CF3


7-5278
phenyl
Me
H
F
F
H
H
I
H
heptafluoroisopropyl
H
CF3


7-5298
3-cyanophenyl
Me
H
F
F
H
H
I
H
heptafluoroisopropyl
H
CF3


7-5299
4-cyanophenyl
Me
H
F
F
H
H
I
H
heptafluoroisopropyl
H
CF3


7-5314
2-chloropyridin-3-yl
Me
H
F
F
H
H
I
H
heptafluoroisopropyl
H
CF3


7-5356
phenyl
Me
H
F
F
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-5376
3-cyanophenyl
Me
H
F
F
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-5377
4-cyanophenyl
Me
H
F
F
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-5392
2-chloropyridin-3-yl
Me
H
F
F
H
H
I
H
nonafluoro-2-butyl
H
CF3


7-5434
phenyl
Me
H
F
F
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


7-5465
2-chloropyridin-3-yl
Me
H
F
F
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


7-5490
phenyl
Me
H
F
F
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


7-5521
2-chloropyridin-3-yl
Me
H
F
F
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


7-5546
phenyl
Me
H
F
F
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


7-5577
2-chloropyridin-3-yl
Me
H
F
F
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


7-5602
phenyl
Me
H
F
F
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


7-5633
2-chloropyridin-3-yl
Me
H
F
F
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


7-5658
phenyl
Me
H
F
F
H
H
CF3
H
heptafluoroisopropyl
H
CF3


7-5678
3-cyanophenyl
Me
H
F
F
H
H
CF3
H
heptafluoroisopropyl
H
CF3


7-5679
4-cyanophenyl
Me
H
F
F
H
H
CF3
H
heptafluoroisopropyl
H
CF3


7-5694
2-chloropyridin-3-yl
Me
H
F
F
H
H
CF3
H
heptafluoroisopropyl
H
CF3


7-5726
phenyl
Me
H
F
F
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


7-5746
3-cyanophenyl
Me
H
F
F
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


7-5747
4-cyanophenyl
Me
H
F
F
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


7-5762
2-chloropyridin-3-yl
Me
H
F
F
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


7-5794
phenyl
Me
H
F
F
F
H
Cl
H
pentafluoroethyl
H
Cl


7-5795
phenyl
Me
H
F
F
F
H
Br
H
heptafluoroisopropyl
H
Br


7-5796
phenyl
Me
H
F
F
F
H
Br
H
heptafluoroisopropyl
H
OCF3


7-5797
phenyl
Me
H
F
F
F
H
I
H
heptafluoroisopropyl
H
CF3


7-5798
phenyl
Me
H
F
F
F
H
CF3
H
heptafluoroisopropyl
H
CF3


7-5799
phenyl
Me
H
F
F
F
H
I
H
nonafluoro-2-butyl
H
I


7-5800
phenyl
Me
H
F
F
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


7-5801
phenyl
Me
H
F
F
F
H
Br
H
nonafluoro-2-butyl
H
CF3


7-5802
phenyl
Me
H
F
F
F
H
CF3
H
nonafluoro-2-butyl
H
CF3


7-5803
phenyl
Me
H
H
H
F
H
Cl
H
pentafluoroethyl
H
Cl


7-5804
phenyl
Me
H
H
H
F
H
Br
H
heptafluoroisopropyl
H
Br


7-5805
phenyl
Me
H
H
H
F
H
Br
H
heptafluoroisopropyl
H
OCF3


7-5806
phenyl
Me
H
H
H
F
H
I
H
heptafluoroisopropyl
H
CF3


7-5807
phenyl
Me
H
H
H
F
H
CF3
H
heptafluoroisopropyl
H
CF3


7-5808
phenyl
Me
H
H
H
F
H
I
H
nonafluoro-2-butyl
H
I


7-5809
phenyl
Me
H
H
H
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


7-5810
phenyl
Me
H
H
H
F
H
Br
H
nonafluoro-2-butyl
H
CF3


7-5811
phenyl
Me
H
H
H
F
H
CF3
H
nonafluoro-2-butyl
H
CF3


7-5812
phenyl
Me
H
H
H
H
F
Cl
H
pentafluoroethyl
H
Cl


7-5813
phenyl
Me
H
H
H
H
F
Br
H
heptafluoroisopropyl
H
Br


7-5814
phenyl
Me
H
H
H
H
F
Br
H
heptafluoroisopropyl
H
OCF3


7-5815
phenyl
Me
H
H
H
H
F
I
H
heptafluoroisopropyl
H
CF3


7-5816
phenyl
Me
H
H
H
H
F
CF3
H
heptafluoroisopropyl
H
CF3


7-5817
phenyl
Me
H
H
H
H
F
I
H
nonafluoro-2-butyl
H
I


7-5818
phenyl
Me
H
H
H
H
F
Cl
H
nonafluoro-2-butyl
H
OCF3


7-5819
phenyl
Me
H
H
H
H
F
Br
H
nonafluoro-2-butyl
H
CF3


7-5820
phenyl
Me
H
H
H
H
F
CF3
H
nonafluoro-2-butyl
H
CF3


7-5821
phenyl
Me
H
F
H
F
H
Cl
H
pentafluoroethyl
H
Cl


7-5822
phenyl
Me
H
F
H
F
H
Br
H
heptafluoroisopropyl
H
Br


7-5823
phenyl
Me
H
F
H
F
H
Br
H
heptafluoroisopropyl
H
OCF3


7-5824
phenyl
Me
H
F
H
F
H
I
H
heptafluoroisopropyl
H
CF3


7-5825
phenyl
Me
H
F
H
F
H
CF3
H
heptafluoroisopropyl
H
CF3


7-5826
phenyl
Me
H
F
H
F
H
I
H
nonafluoro-2-butyl
H
I


7-5827
phenyl
Me
H
F
H
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


7-5828
phenyl
Me
H
F
H
F
H
Br
H
nonafluoro-2-butyl
H
CF3


7-5829
phenyl
Me
H
F
H
F
H
CF3
H
nonafluoro-2-butyl
H
CF3


7-5830
phenyl
Me
H
F
H
H
F
Cl
H
pentafluoroethyl
H
Cl


7-5831
phenyl
Me
H
F
H
H
F
Br
H
heptafluoroisopropyl
H
Br


7-5832
phenyl
Me
H
F
H
H
F
Br
H
heptafluoroisopropyl
H
OCF3


7-5833
phenyl
Me
H
F
H
H
F
I
H
heptafluoroisopropyl
H
CF3


7-5834
phenyl
Me
H
F
H
H
F
CF3
H
heptafluoroisopropyl
H
CF3


7-5835
phenyl
Me
H
F
H
H
F
I
H
nonafluoro-2-butyl
H
I


7-5836
phenyl
Me
H
F
H
H
F
Cl
H
nonafluoro-2-butyl
H
OCF3


7-5837
phenyl
Me
H
F
H
H
F
Br
H
nonafluoro-2-butyl
H
CF3


7-5838
phenyl
Me
H
F
H
H
F
CF3
H
nonafluoro-2-butyl
H
CF3


7-5839
phenyl
Me
H
H
F
F
H
Cl
H
pentafluoroethyl
H
Cl


7-5840
phenyl
Me
H
H
F
F
H
Br
H
heptafluoroisopropyl
H
Br


7-5841
phenyl
Me
H
H
F
F
H
Br
H
heptafluoroisopropyl
H
OCF3


7-5842
phenyl
Me
H
H
F
F
H
I
H
heptafluoroisopropyl
H
CF3


7-5843
phenyl
Me
H
H
F
F
H
CF3
H
heptafluoroisopropyl
H
CF3


7-5844
phenyl
Me
H
H
F
F
H
I
H
nonafluoro-2-butyl
H
I


7-5845
phenyl
Me
H
H
F
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


7-5846
phenyl
Me
H
H
F
F
H
Br
H
nonafluoro-2-butyl
H
CF3


7-5847
phenyl
Me
H
H
F
F
H
CF3
H
nonafluoro-2-butyl
H
CF3


7-5848
phenyl
Me
H
H
F
H
F
Cl
H
pentafluoroethyl
H
Cl


7-5849
phenyl
Me
H
H
F
H
F
Br
H
heptafluoroisopropyl
H
Br


7-5850
phenyl
Me
H
H
F
H
F
Br
H
heptafluoroisopropyl
H
OCF3


7-5851
phenyl
Me
H
H
F
H
F
I
H
heptafluoroisopropyl
H
CF3


7-5852
phenyl
Me
H
H
F
H
F
CF3
H
heptafluoroisopropyl
H
CF3


7-5853
phenyl
Me
H
H
F
H
F
I
H
nonafluoro-2-butyl
H
I


7-5854
phenyl
Me
H
H
F
H
F
Cl
H
nonafluoro-2-butyl
H
OCF3


7-5855
phenyl
Me
H
H
F
H
F
Br
H
nonafluoro-2-butyl
H
CF3


7-5856
phenyl
Me
H
H
F
H
F
CF3
H
nonafluoro-2-butyl
H
CF3


7-5857
phenyl
Me
H
H
H
F
F
Cl
H
pentafluoroethyl
H
Cl


7-5858
phenyl
Me
H
H
H
F
F
Br
H
heptafluoroisopropyl
H
Br


7-5859
phenyl
Me
H
H
H
F
F
Br
H
heptafluoroisopropyl
H
OCF3


7-5860
phenyl
Me
H
H
H
F
F
I
H
heptafluoroisopropyl
H
CF3


7-5861
phenyl
Me
H
H
H
F
F
CF3
H
heptafluoroisopropyl
H
CF3


7-5862
phenyl
Me
H
H
H
F
F
I
H
nonafluoro-2-butyl
H
I


7-5863
phenyl
Me
H
H
H
F
F
Cl
H
nonafluoro-2-butyl
H
OCF3


7-5864
phenyl
Me
H
H
H
F
F
Br
H
nonafluoro-2-butyl
H
CF3


7-5865
phenyl
Me
H
H
H
F
F
CF3
H
nonafluoro-2-butyl
H
CF3


7-5866
phenyl
Me
H
F
F
H
F
Cl
H
pentafluoroethyl
H
Cl


7-5867
phenyl
Me
H
F
F
H
F
Br
H
heptafluoroisopropyl
H
Br


7-5868
phenyl
Me
H
F
F
H
F
Br
H
heptafluoroisopropyl
H
OCF3


7-5869
phenyl
Me
H
F
F
H
F
I
H
heptafluoroisopropyl
H
CF3


7-5870
phenyl
Me
H
F
F
H
F
CF3
H
heptafluoroisopropyl
H
CF3


7-5871
phenyl
Me
H
F
F
H
F
I
H
nonafluoro-2-butyl
H
I


7-5872
phenyl
Me
H
F
F
H
F
Cl
H
nonafluoro-2-butyl
H
OCF3


7-5873
phenyl
Me
H
F
F
H
F
Br
H
nonafluoro-2-butyl
H
CF3


7-5874
phenyl
Me
H
F
F
H
F
CF3
H
nonafluoro-2-butyl
H
CF3


7-5875
phenyl
Me
H
F
H
F
F
Cl
H
pentafluoroethyl
H
Cl


7-5876
phenyl
Me
H
F
H
F
F
Br
H
heptafluoroisopropyl
H
Br


7-5877
phenyl
Me
H
F
H
F
F
Br
H
heptafluoroisopropyl
H
OCF3


7-5878
phenyl
Me
H
F
H
F
F
I
H
heptafluoroisopropyl
H
CF3


7-5879
phenyl
Me
H
F
H
F
F
CF3
H
heptafluoroisopropyl
H
CF3


7-5880
phenyl
Me
H
F
H
F
F
I
H
nonafluoro-2-butyl
H
I


7-5881
phenyl
Me
H
F
H
F
F
Cl
H
nonafluoro-2-butyl
H
OCF3


7-5882
phenyl
Me
H
F
H
F
F
Br
H
nonafluoro-2-butyl
H
CF3


7-5883
phenyl
Me
H
F
H
F
F
CF3
H
nonafluoro-2-butyl
H
CF3


7-5884
phenyl
Me
H
H
F
F
F
Cl
H
pentafluoroethyl
H
Cl


7-5885
phenyl
Me
H
H
F
F
F
Br
H
heptafluoroisopropyl
H
Br


7-5886
phenyl
Me
H
H
F
F
F
Br
H
heptafluoroisopropyl
H
OCF3


7-5887
phenyl
Me
H
H
F
F
F
I
H
heptafluoroisopropyl
H
CF3


7-5888
phenyl
Me
H
H
F
F
F
CF3
H
heptafluoroisopropyl
H
CF3


7-5889
phenyl
Me
H
H
F
F
F
I
H
nonafluoro-2-butyl
H
I


7-5890
phenyl
Me
H
H
F
F
F
Cl
H
nonafluoro-2-butyl
H
OCF3


7-5891
phenyl
Me
H
H
F
F
F
Br
H
nonafluoro-2-butyl
H
CF3


7-5892
phenyl
Me
H
H
F
F
F
CF3
H
nonafluoro-2-butyl
H
CF3


7-5893
phenyl
Me
H
F
F
F
F
Cl
H
pentafluoroethyl
H
Cl


7-5894
phenyl
Me
H
F
F
F
F
Br
H
heptafluoroisopropyl
H
Br


7-5895
phenyl
Me
H
F
F
F
F
Br
H
heptafluoroisopropyl
H
OCF3


7-5896
phenyl
Me
H
F
F
F
F
I
H
heptafluoroisopropyl
H
CF3


7-5897
phenyl
Me
H
F
F
F
F
CF3
H
heptafluoroisopropyl
H
CF3


7-5898
phenyl
Me
H
F
F
F
F
I
H
nonafluoro-2-butyl
H
I


7-5899
phenyl
Me
H
F
F
F
F
Cl
H
nonafluoro-2-butyl
H
OCF3


7-5900
phenyl
Me
H
F
F
F
F
Br
H
nonafluoro-2-butyl
H
CF3


7-5901
phenyl
Me
H
F
F
F
F
CF3
H
nonafluoro-2-butyl
H
CF3


7-5902
phenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
Br


7-5903
2-chloropyridine-3-yl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
Br


7-5904
3-fluorophenyl
Me
H
H
H
H
H
I
H
nonafluoro-2-butyl
H
I


7-5905
4-fluorophenyl
Me
H
H
H
H
H
I
H
nonafluoro-2-butyl
H
I


7-5906
3-fluorophenyl
Me
H
H
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


7-5907
4-fluorophenyl
Me
H
H
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


7-5908
4-(methylsulfonyl)phenyl
Me
H
H
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-5909
pyrimidine-5-yl
Me
H
H
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-5910
3-cyano-5-(methoxycarbonyl)phenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-5911
phenyl
Me
H
H
H
H
H
Br
H
pentafluoroethyl
H
CF3


7-5912
2-chloropyridine-3-yl
Me
H
H
H
H
H
Br
H
pentafluoroethyl
H
CF3











embedded image





















TABLE 8





compound














number
Q1
R1
R2
X1
X2
X3
X4
Y1
Y2
Y3
Y4
Y5







8-1
phenyl
H
Me
H
H
H
H
F
H
nonafluoro-2-butyl
H
F


8-2
3-cyanophenyl
H
Me
H
H
H
H
F
H
nonafluoro-2-butyl
H
F


8-3
4-cyanophenyl
H
Me
H
H
H
H
F
H
nonafluoro-2-butyl
H
F


8-4
2-chloropyridin-3-yl
H
Me
H
H
H
H
F
H
nonafluoro-2-butyl
H
F


8-5
phenyl
H
Me
H
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


8-12
3-cyanophenyl
H
Me
H
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


8-13
4-cyanophenyl
H
Me
H
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


8-24
2-chloropyridin-3-yl
H
Me
H
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


8-38
phenyl
H
Me
H
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


8-45
3-cyanophenyl
H
Me
H
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


8-46
4-cyanophenyl
H
Me
H
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


8-57
2-chloropyridin-3-yl
H
Me
H
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


8-71
phenyl
H
Me
H
H
H
H
I
H
nonafluoro-2-butyl
H
I


8-78
3-cyanophenyl
H
Me
H
H
H
H
I
H
nonafluoro-2-butyl
H
I


8-79
4-cyanophenyl
H
Me
H
H
H
H
I
H
nonafluoro-2-butyl
H
I


8-90
2-chloropyridin-3-yl
H
Me
H
H
H
H
I
H
nonafluoro-2-butyl
H
I


8-104
phenyl
H
Me
H
H
H
H
F
H
nonafluoro-2-butyl
H
Cl


8-105
phenyl
H
Me
H
H
H
H
F
H
nonafluoro-2-butyl
H
Br


8-106
phenyl
H
Me
H
H
H
H
F
H
nonafluoro-2-butyl
H
I


8-107
phenyl
H
Me
H
H
H
H
Cl
H
nonafluoro-2-butyl
H
Br


8-108
phenyl
H
Me
H
H
H
H
Cl
H
nonafluoro-2-butyl
H
I


8-109
phenyl
H
Me
H
H
H
H
Br
H
nonafluoro-2-butyl
H
I


8-110
phenyl
H
Me
H
H
H
H
F
H
heptafluoroisopropyl
H
CF3


8-111
phenyl
H
Me
H
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


8-131
3-cyanophenyl
H
Me
H
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


8-132
4-cyanophenyl
H
Me
H
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


8-147
2-chloropyridin-3-yl
H
Me
H
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


8-189
phenyl
H
Me
H
H
H
H
F
H
nonafluoro-2-butyl
H
CF3


8-190
phenyl
H
Me
H
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


8-210
3-cyanophenyl
H
Me
H
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


8-211
4-cyanophenyl
H
Me
H
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


8-226
2-chloropyridin-3-yl
H
Me
H
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


8-268
phenyl
H
Me
H
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


8-288
3-cyanophenyl
H
Me
H
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


8-289
4-cyanophenyl
H
Me
H
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


8-304
2-chloropyridin-3-yl
H
Me
H
H
H
H
Br
H
heptafluorpisopropyl
H
CF3


8-305
2-bromopyridin-3-yl
H
Me
H
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


8-346
phenyl
H
Me
H
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


8-366
3-cyanophenyl
H
Me
H
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


8-367
4-cyanophenyl
H
Me
H
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


8-382
2-chloropyridin-3-yl
H
Me
H
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


8-424
phenyl
H
Me
H
H
H
H
I
H
heptafluoroisopropyl
H
CF3


8-444
3-cyanophenyl
H
Me
H
H
H
H
I
H
heptafluoroisopropyl
H
CF3


8-445
4-cyanophenyl
H
Me
H
H
H
H
I
H
heptafluoroisopropyl
H
CF3


8-460
2-chloropyridin-3-yl
H
Me
H
H
H
H
I
H
heptafluoroisopropyl
H
CF3


8-502
phenyl
H
Me
H
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


8-522
3-cyanophenyl
H
Me
H
H
H
H
I
H
npnafluoro-2-butyl
H
CF3


8-523
4-cyanophenyl
H
Me
H
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


8-538
2-chloropyridin-3-yl
H
Me
H
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


8-580
phenyl
H
Me
H
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


8-611
2-chloropyridin-3-yl
H
Me
H
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


8-636
phenyl
H
Me
H
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


8-667
2-chloropyridin-3-yl
H
Me
H
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


8-692
phenyl
H
Me
H
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


8-723
2-chloropyridin-3-yl
H
Me
H
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


8-748
phenyl
H
Me
H
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


8-779
2-chloropyridin-3-yl
H
Me
H
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


8-804
phenyl
H
Me
H
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


8-824
3-cyanophenyl
H
Me
H
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


8-825
4-cyanophenyl
H
Me
H
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


8-840
2-chloropyridin-3-yl
H
Me
H
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


8-841
2-bromopyridin-3-yl
H
Me
H
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


8-872
phenyl
H
Me
H
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


8-892
3-cyanophenyl
H
Me
H
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


8-893
4-cyanophenyl
H
Me
H
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


8-908
2-chloropyridin-3-yl
H
Me
H
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


8-940
phenyl
H
Me
F
H
H
H
F
H
heptafluoroisopropyl
H
F


8-941
3-cyanophenyl
H
Me
F
H
H
H
F
H
heptafluoroisopropyl
H
F


8-942
4-cyanophenyl
H
Me
F
H
H
H
F
H
heptafluoroisopropyl
H
F


8-943
2-chloropyridin-3-yl
H
Me
F
H
H
H
F
H
heptafluoroisopropyl
H
F


8-944
phenyl
H
Me
F
H
H
H
F
H
nonafluoro-2-butyl
H
F


8-945
3-cyanophenyl
H
Me
F
H
H
H
F
H
nonafluoro-2-butyl
H
F


8-946
4-cyanophenyl
H
Me
F
H
H
H
F
H
nonafluoro-2-butyl
H
F


8-947
2-chloropyridin-3-yl
H
Me
F
H
H
H
F
H
nonafluoro-2-butyl
H
F


8-948
phenyl
H
Me
F
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


8-952
2-chlorophenyl
H
Me
F
H
H
H
F
H
heptafluoroisopropyl
H
Cl


8-956
3-bromophenyl
H
Me
F
H
H
H
F
H
heptafluoroisopropyl
H
Br


8-961
(2-trifluoromethyl)phenyl
H
i-Pr
F
H
H
H
F
H
heptafluoroisopropyl
H
I


8-964
2-nitrophenyl
H
Me
F
H
H
H
Cl
H
heptafluoroisopropyl
H
Br


8-968
3-cyanophenyl
H
Me
F
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


8-969
4-cyanophenyl
H
Me
F
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


8-970
2,6-difluorophenyl
H
Me
F
H
H
H
Cl
H
heptafluoroisopropyl
H
I


8-982
pyridin-3-yl
H
Me
F
H
H
H
Br
H
heptafluoroisopropyl
H
I


8-984
2-chloropyridin-3-yl
H
Me
F
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


8-1026
phenyl
H
Me
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


8-1046
3-cyanophenyl
H
Me
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


8-1047
4-cyanophenyl
H
Me
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


8-1062
2-chloropyridin-3-yl
H
Me
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


8-1104
phenyl
H
Me
F
H
H
H
Br
H
heptafluoroisopropyl
H
Br


8-1124
3-cyanophenyl
H
Me
F
H
H
H
Br
H
heptafluoroisopropyl
H
Br


8-1125
4-cyanophenyl
H
Me
F
H
H
H
Br
H
heptafluoroisopropyl
H
Br


8-1140
2-chloropyridin-3-yl
H
Me
F
H
H
H
Br
H
heptafluoroisopropyl
H
Br


8-1182
phenyl
H
Me
F
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


8-1202
3-cyanophenyl
H
Me
F
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


8-1203
4-cyanophenyl
H
Me
F
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


8-1218
2-chloropyridin-3-yl
H
Me
F
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


8-1260
phenyl
H
Me
F
H
H
H
I
H
heptafluoroisopropyl
H
I


8-1280
3-cyanophenyl
H
Me
F
H
H
H
I
H
heptafluoroisopropyl
H
I


8-1281
4-cyanophenyl
H
Me
F
H
H
H
I
H
heptafluoroisopropyl
H
I


8-1296
2-chloropyridin-3-yl
H
Me
F
H
H
H
I
H
heptafluoroisopropyl
H
I


8-1338
phenyl
H
Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
I


8-1358
3-cyanophenyl
H
Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
I


8-1359
4-cyanophenyl
H
Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
I


8-1374
2-chloropyridin-3-yl
H
Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
I


8-1416
phenyl
H
Me
F
H
H
H
F
H
heptafluoroisopropyl
H
CF3


8-1417
phenyl
H
Me
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


8-1431
(3-trifluoromethyl)phenyl
H
Et
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


8-1437
3-cyanophenyl
H
Me
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


8-1438
4-cyanophenyl
H
Me
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


8-1442
2-chloro-4-fluorophenyl
H
n-Pr
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


8-1453
2-chloropyridin-3-yl
H
Me
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


8-1459
6-fluoropyridin-3-yl
H
i-Pr
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


8-1475
4-bromopyridin-3-yl
H
CH2CH═CH2
F
H
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


8-1482
pyridin-4-yl
H
CN
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


8-1495
phenyl
H
Me
F
H
H
H
F
H
nonafluoro-2-butyl
H
CF3


8-1496
phenyl
H
Me
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


8-1504
3-bromophenyl
H
CH2C≡CH
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


8-1511
(4-trifluoromethyl)phenyl
H
NH2
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


8-1516
3-cyanophenyl
H
Me
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


8-1517
4-cyanophenyl
H
Me
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


8-1524
2-bromo-4-chlorophenyl
H
C(O)OMe
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


8-1532
2-chloropyridin-3-yl
H
Me
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


8-1545
5-fluoropyridin-3-yl
H
C(O)OEt
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


8-1554
4-bromopyridin-3-yl
H
C(O)C(O)Me
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


8-1557
4-nitropyridin-3-yl
H
C(O)C(O)Et
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


8-1571
5-iodopyridin-2-yl
H
C(O)Me
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


8-1573
4-cyanopyridin-2-yl
H
C(O)Et
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


8-1574
phenyl
H
Me
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


8-1588
(3-trifluoromethyl)phenyl
H
S(O)2Me
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


8-1594
3-cyanophenyl
H
Me
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


8-1595
4-cyanophenyl
H
Me
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


8-1606
4-cyano-2-fluorophenyl
H
S(O)2Et
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


8-1610
2-chloropyridin-3-yl
H
Me
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


8-1621
6-nitropyridin-3-yl
H
CH2Ph
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


8-1630
4-fluoropyridin-3-yl
H
CH2(3-Py)
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


8-1651
4-cyanopyridin-2-yl
H
CH2(3-Py—N-
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3





oxide)


8-1652
phenyl
H
Me
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


8-1672
3-cyanophenyl
H
Me
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


8-1673
4-cyanophenyl
H
Me
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


8-1679
4-bromo-2-chlorophenyl
H
Et
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


8-1688
2-chloropyridin-3-yl
H
Me
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


8-1705
5-(trifluoromethyl)pyridin-3-yl
H
CN
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


8-1730
phenyl
H
Me
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


8-1750
3-cyanophenyl
H
Me
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


8-1751
4-cyanophenyl
H
Me
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


8-1766
2-chloropyridin-3-yl
H
Me
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


8-1779
5-fluoropyridin-3-yl
H
C(O)Me
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


8-1808
phenyl
H
Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


8-1828
3-cyanophenyl
H
Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


8-1829
4-cyanophenyl
H
Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


8-1844
2-chloropyridin-3-yl
H
Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


8-1886
phenyl
H
Me
F
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


8-1901
3-cyanophenyl
H
Me
F
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


8-1902
4-cyanophenyl
H
Me
F
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


8-1917
2-chloropyridin-3-yl
H
Me
F
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


8-1942
phenyl
H
Me
F
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


8-1957
3-cyanophenyl
H
Me
F
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


8-1958
4-cyanophenyl
H
Me
F
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


8-1973
2-chloropyridin-3-yl
H
Me
F
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


8-1998
phenyl
H
Me
F
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


8-2013
3-cyanophenyl
H
Me
F
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


8-2014
4-cyanophenyl
H
Me
F
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


8-2029
2-chloropyridin-3-yl
H
Me
F
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


8-2054
phenyl
H
Me
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


8-2069
3-cyanophenyl
H
Me
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


8-2070
4-cyanophenyl
H
Me
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


8-2085
2-chloropyridin-3-yl
H
Me
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


8-2110
phenyl
H
Me
F
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


8-2130
3-cyanophenyl
H
Me
F
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


8-2131
4-cyanophenyl
H
Me
F
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


8-2146
2-chloropyridin-3-yl
H
Me
F
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


8-2178
phenyl
H
Me
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


8-2198
3-cyanophenyl
H
Me
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


8-2199
4-cyanophenyl
H
Me
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


8-2214
2-chloropyridin-3-yl
H
Me
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


8-2246
phenyl
H
Me
H
F
H
H
F
H
heptafluoroisopropyl
H
F


8-2247
3-cyanophenyl
H
Me
H
F
H
H
F
H
heptafluoroisopropyl
H
F


8-2248
4-cyanophenyl
H
Me
H
F
H
H
F
H
heptafluoroisopropyl
H
F


8-2249
2-chloropyridin-3-yl
H
Me
H
F
H
H
F
H
heptafluoroisopropyl
H
F


8-2250
phenyl
H
Me
H
F
H
H
F
H
nonafluoro-2-butyl
H
F


8-2251
3-cyanophenyl
H
Me
H
F
H
H
F
H
nonafluoro-2-butyl
H
F


8-2252
4-cyanophenyl
H
Me
H
F
H
H
F
H
nonafluoro-2-butyl
H
F


8-2253
2-chloropyridin-3-yl
H
Me
H
F
H
H
F
H
nonafluoro-2-butyl
H
F


8-2254
phenyl
H
Me
H
F
H
H
Cl
H
heptafluoroisopropyl
H
Cl


8-2274
3-cyanophenyl
H
Me
H
F
H
H
Cl
H
heptafluoroisopropyl
H
Cl


8-2275
4-cyanophenyl
H
Me
H
F
H
H
Cl
H
heptafluoroisopropyl
H
Cl


8-2290
2-chloropyridin-3-yl
H
Me
H
F
H
H
Cl
H
heptafluoroisopropyl
H
Cl


8-2332
phenyl
H
Me
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


8-2352
3-cyanophenyl
H
Me
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


8-2353
4-cyanophenyl
H
Me
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


8-2368
2-chloropyridin-3-yl
H
Me
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


8-2410
phenyl
H
Me
H
F
H
H
Br
H
heptafluoroisopropyl
H
Br


8-2430
3-cyanophenyl
H
Me
H
F
H
H
Br
H
heptafluoroisopropyl
H
Br


8-2431
4-cyanophenyl
H
Me
H
F
H
H
Br
H
heptafluoroisopropyl
H
Br


8-2446
2-chloropyridin-3-yl
H
Me
H
F
H
H
Br
H
heptafluoroisopropyl
H
Br


8-2488
phenyl
H
Me
H
F
H
H
Br
H
nonafluoro-2-butyl
H
Br


8-2508
3-cyanophenyl
H
Me
H
F
H
H
Br
H
nonafluoro-2-butyl
H
Br


8-2509
4-cyanophenyl
H
Me
H
F
H
H
Br
H
nonafluoro-2-butyl
H
Br


8-2524
2-chloropyridin-3-yl
H
Me
H
F
H
H
Br
H
nonafluoro-2-butyl
H
Br


8-2566
phenyl
H
Me
H
F
H
H
I
H
heptafluoroisopropyl
H
I


8-2586
3-cyanophenyl
H
Me
H
F
H
H
I
H
heptafluoroisopropyl
H
I


8-2587
4-cyanophenyl
H
Me
H
F
H
H
I
H
heptafluoroisopropyl
H
I


8-2602
2-chloropyridin-3-yl
H
Me
H
F
H
H
I
H
heptafluoroisopropyl
H
I


8-2644
phenyl
H
Me
H
F
H
H
I
H
nonafluoro-2-butyl
H
I


8-2664
3-cyanophenyl
H
Me
H
F
H
H
I
H
nonafluoro-2-butyl
H
I


8-2665
4-cyanophenyl
H
Me
H
F
H
H
I
H
nonafluoro-2-butyl
H
I


8-2680
2-chloropyridin-3-yl
H
Me
H
F
H
H
I
H
nonafluoro-2-butyl
H
I


8-2722
phenyl
H
Me
H
F
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


8-2742
3-cyanophenyl
H
Me
H
F
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


8-2743
4-cyanophenyl
H
Me
H
F
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


8-2758
2-chloropyridin-3-yl
H
Me
H
F
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


8-2800
phenyl
H
Me
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


8-2820
3-cyanophenyl
H
Me
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


8-2821
4-cyanophenyl
H
Me
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


8-2836
2-chloropyridin-3-yl
H
Me
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


8-2878
phenyl
H
Me
H
F
H
H
Br
H
heptafluoroisopropyl
H
OCF3


8-2898
3-cyanophenyl
H
Me
H
F
H
H
Br
H
heptafluoroisopropyl
H
OCF3


8-2899
4-cyanophenyl
H
Me
H
F
H
H
Br
H
heptafluoroisopropyl
H
OCF3


8-2914
2-chloropyridin-3-yl
H
Me
H
F
H
H
Br
H
heptafluoroisopropyl
H
OCF3


8-2956
phenyl
H
Me
H
F
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


8-2976
3-cyanophenyl
H
Me
H
F
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


8-2977
4-cyanophenyl
H
Me
H
F
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


8-2992
2-chloropyridin-3-yl
H
Me
H
F
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


8-3034
phenyl
H
Me
H
F
H
H
I
H
heptafluoroisopropyl
H
OCF3


8-3054
3-cyanophenyl
H
Me
H
F
H
H
I
H
heptafluoroisopropyl
H
OCF3


8-3055
4-cyanophenyl
H
Me
H
F
H
H
I
H
heptafluoroisopropyl
H
OCF3


8-3070
2-chloropyridin-3-yl
H
Me
H
F
H
H
I
H
heptafluoroisopropyl
H
OCF3


8-3112
phenyl
H
Me
H
F
H
H
I
H
nonafluoro-2-butyl
H
OCF3


8-3132
3-cyanophenyl
H
Me
H
F
H
H
I
H
nonafluoro-2-butyl
H
OCF3


8-3133
4-cyanophenyl
H
Me
H
F
H
H
I
H
nonafluoro-2-butyl
H
OCF3


8-3148
2-chloropyridin-3-yl
H
Me
H
F
H
H
I
H
nonafluoro-2-butyl
H
OCF3


8-3190
phenyl
H
Me
H
F
H
H
F
H
heptafluoroisopropyl
H
CF3


8-3191
phenyl
H
Me
H
F
H
H
Cl
H
heptafluoroisopropyl
H
CF3


8-3211
3-cyanophenyl
H
Me
H
F
H
H
Cl
H
heptafluoroisopropyl
H
CF3


8-3212
4-cyanophenyl
H
Me
H
F
H
H
Cl
H
heptafluoroisopropyl
H
CF3


8-3227
2-chloropyridin-3-yl
H
Me
H
F
H
H
Cl
H
heptafluoroisopropyl
H
CF3


8-3269
phenyl
H
Me
H
F
H
H
F
H
nonafluoro-2-butyl
H
CF3


8-3270
phenyl
H
Me
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


8-3290
3-cyanophenyl
H
Me
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


8-3291
4-cyanophenyl
H
Me
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


8-3306
2-chloropyridin-3-yl
H
Me
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


8-3348
phenyl
H
Me
H
F
H
H
Br
H
heptafluoroisopropyl
H
CF3


8-3368
3-cyanophenyl
H
Me
H
F
H
H
Br
H
heptafluoroisopropyl
H
CF3


8-3369
4-cyanophenyl
H
Me
H
F
H
H
Br
H
heptafluoroisopropyl
H
CF3


8-3384
2-chloropyridin-3-yl
H
Me
H
F
H
H
Br
H
heptafluoroisopropyl
H
CF3


8-3426
phenyl
H
Me
H
F
H
H
Br
H
nonafluoro-2-butyl
H
CF3


8-3446
3-cyanophenyl
H
Me
H
F
H
H
Br
H
nonafluoro-2-butyl
H
CF3


8-3447
4-cyanophenyl
H
Me
H
F
H
H
Br
H
nonafluoro-2-butyl
H
CF3


8-3462
2-chloropyridin-3-yl
H
Me
H
F
H
H
Br
H
nonafluoro-2-butyl
H
CF3


8-3504
phenyl
H
Me
H
F
H
H
I
H
heptafluoroisopropyl
H
CF3


8-3524
3-cyanophenyl
H
Me
H
F
H
H
I
H
heptafluoroisopropyl
H
CF3


8-3525
4-cyanophenyl
H
Me
H
F
H
H
I
H
heptafluoroisopropyl
H
CF3


8-3540
2-chloropyridin-3-yl
H
Me
H
F
H
H
I
H
heptafluoroisopropyl
H
CF3


8-3582
phenyl
H
Me
H
F
H
H
I
H
nonafluoro-2-butyl
H
CF3


8-3602
3-cyanophenyl
H
Me
H
F
H
H
I
H
nonafluoro-2-butyl
H
CF3


8-3603
4-cyanophenyl
H
Me
H
F
H
H
I
H
nonafluoro-2-butyl
H
CF3


8-3618
2-chloropyridin-3-yl
H
Me
H
F
H
H
I
H
nonafluoro-2-butyl
H
CF3


8-3660
phenyl
H
Me
H
F
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


8-3691
2-chloropyridin-3-yl
H
Me
H
F
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


8-3716
phenyl
H
Me
H
F
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


8-3747
2-chloropyridin-3-yl
H
Me
H
F
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


8-3772
phenyl
H
Me
H
F
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


8-3803
2-chloropyridin-3-yl
H
Me
H
F
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


8-3828
phenyl
H
Me
H
F
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


8-3859
2-chloropyridin-3-yl
H
Me
H
F
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


8-3884
phenyl
H
Me
H
F
H
H
CF3
H
heptafluoroisopropyl
H
CF3


8-3904
3-cyanophenyl
H
Me
H
F
H
H
CF3
H
heptafluoroisopropyl
H
CF3


8-3905
4-cyanophenyl
H
Me
H
F
H
H
CF3
H
heptafluoroisopropyl
H
CF3


8-3920
2-chloropyridin-3-yl
H
Me
H
F
H
H
CF3
H
heptafluoroisopropyl
H
CF3


8-3952
phenyl
H
Me
H
F
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


8-3972
3-cyanophenyl
H
Me
H
F
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


8-3973
4-cyanophenyl
H
Me
H
F
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


8-3988
2-chloropyridin-3-yl
H
Me
H
F
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


8-4020
phenyl
H
Me
F
F
H
H
F
H
heptafluoroisopropyl
H
F


8-4021
3-cyanophenyl
H
Me
F
F
H
H
F
H
heptafluoroisopropyl
H
F


8-4022
4-cyanophenyl
H
Me
F
F
H
H
F
H
heptafluoroisopropyl
H
F


8-4023
2-chloropyridin-3-yl
H
Me
F
F
H
H
F
H
heptafluoroisopropyl
H
F


8-4024
phenyl
H
Me
F
F
H
H
F
H
nonafluoro-2-butyl
H
F


8-4025
3-cyanophenyl
H
Me
F
F
H
H
F
H
nonafluoro-2-butyl
H
F


8-4026
4-cyanophenyl
H
Me
F
F
H
H
F
H
nonafluoro-2-butyl
H
F


8-4027
2-chloropyridin-3-yl
H
Me
F
F
H
H
F
H
nonafluoro-2-butyl
H
F


8-4028
phenyl
H
Me
F
F
H
H
Cl
H
heptafluoroisopropyl
H
Cl


8-4048
3-cyanophenyl
H
Me
F
F
H
H
Cl
H
heptafluoroisopropyl
H
Cl


8-4049
4-cyanophenyl
H
Me
F
F
H
H
Cl
H
heptafluoroisopropyl
H
Cl


8-4064
2-chloropyridin-3-yl
H
Me
F
F
H
H
Cl
H
heptafluoroisopropyl
H
Cl


8-4106
phenyl
H
Me
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


8-4126
3-cyanophenyl
H
Me
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


8-4127
4-cyanophenyl
H
Me
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


8-4142
2-chloropyridin-3-yl
H
Me
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


8-4184
phenyl
H
Me
F
F
H
H
Br
H
heptafluoroisopropyl
H
Br


8-4204
3-cyanophenyl
H
Me
F
F
H
H
Br
H
heptafluoroisopropyl
H
Br


8-4205
4-cyanophenyl
H
Me
F
F
H
H
Br
H
heptafluoroisopropyl
H
Br


8-4220
2-chloropyridin-3-yl
H
Me
F
F
H
H
Br
H
heptafluoroisopropyl
H
Br


8-4262
phenyl
H
Me
F
F
H
H
Br
H
nonafluoro-2-butyl
H
Br


8-4282
3-cyanophenyl
H
Me
F
F
H
H
Br
H
nonafluoro-2-butyl
H
Br


8-4283
4-cyanophenyl
H
Me
F
F
H
H
Br
H
nonafluoro-2-butyl
H
Br


8-4298
2-chloropyridin-3-yl
H
Me
F
F
H
H
Br
H
nonafluoro-2-butyl
H
Br


8-4340
phenyl
H
Me
F
F
H
H
I
H
heptafluoroisopropyl
H
I


8-4360
3-cyanophenyl
H
Me
F
F
H
H
I
H
heptafluoroisopropyl
H
I


8-4361
4-cyanophenyl
H
Me
F
F
H
H
I
H
heptafluoroisopropyl
H
I


8-4376
2-chloropyridin-3-yl
H
Me
F
F
H
H
I
H
heptafluoroisopropyl
H
I


8-4418
phenyl
H
Me
F
F
H
H
I
H
nonafluoro-2-butyl
H
I


8-4438
3-cyanophenyl
H
Me
F
F
H
H
I
H
nonafluoro-2-butyl
H
I


8-4439
4-cyanophenyl
H
Me
F
F
H
H
I
H
nonafluoro-2-butyl
H
I


8-4454
2-chloropyridin-3-yl
H
Me
F
F
H
H
I
H
nonafluoro-2-butyl
H
I


8-4496
phenyl
H
Me
F
F
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


8-4516
3-cyanophenyl
H
Me
F
F
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


8-4517
4-cyanophenyl
H
Me
F
F
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


8-4532
2-chloropyridin-3-yl
H
Me
F
F
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


8-4574
phenyl
H
Me
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


8-4594
3-cyanophenyl
H
Me
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


8-4595
4-cyanophenyl
H
Me
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


8-4610
2-chloropyridin-3-yl
H
Me
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


8-4652
phenyl
H
Me
F
F
H
H
Br
H
heptafluoroisopropyl
H
OCF3


8-4672
3-cyanophenyl
H
Me
F
F
H
H
Br
H
heptafluoroisopropyl
H
OCF3


8-4673
4-cyanophenyl
H
Me
F
F
H
H
Br
H
heptafluoroisopropyl
H
OCF3


8-4688
2-chloropyridin-3-yl
H
Me
F
F
H
H
Br
H
heptafluoroisopropyl
H
OCF3


8-4730
phenyl
H
Me
F
F
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


8-4750
3-cyanophenyl
H
Me
F
F
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


8-4751
4-cyanophenyl
H
Me
F
F
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


8-4808
phenyl
H
Me
F
F
H
H
I
H
heptafluoroisopropyl
H
OCF3


8-4828
3-cyanophenyl
H
Me
F
F
H
H
I
H
heptafluoroisopropyl
H
OCF3


8-4829
4-cyanophenyl
H
Me
F
F
H
H
I
H
heptafluoroisopropyl
H
OCF3


8-4844
2-chloropyridin-3-yl
H
Me
F
F
H
H
I
H
heptafluoroisopropyl
H
OCF3


8-4886
phenyl
H
Me
F
F
H
H
I
H
nonafluoro-2-butyl
H
OCF3


8-4906
3-cyanophenyl
H
Me
F
F
H
H
I
H
nonafluoro-2-butyl
H
OCF3


8-4907
4-cyanophenyl
H
Me
F
F
H
H
I
H
nonafluoro-2-butyl
H
OCF3


8-4922
2-chloropyridin-3-yl
H
Me
F
F
H
H
I
H
nonafluoro-2-butyl
H
OCF3


8-4964
phenyl
H
Me
F
F
H
H
F
H
heptafluoroisopropyl
H
CF3


8-4965
phenyl
H
Me
F
F
H
H
Cl
H
heptafluoroisopropyl
H
CF3


8-4985
3-cyanophenyl
H
Me
F
F
H
H
Cl
H
heptafluoroisopropyl
H
CF3


8-4986
4-cyanophenyl
H
Me
F
F
H
H
Cl
H
heptafluoroisopropyl
H
CF3


8-5001
2-chloropyridin-3-yl
H
Me
F
F
H
H
Cl
H
heptafluoroisopropyl
H
CF3


8-5043
phenyl
H
Me
F
F
H
H
F
H
nonafluoro-2-butyl
H
CF3


8-5044
phenyl
H
Me
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


8-5064
3-cyanophenyl
H
Me
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


8-5065
4-cyanophenyl
H
Me
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


8-5080
2-chloropyridin-3-yl
H
Me
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


8-5122
phenyl
H
Me
F
F
H
H
Br
H
heptafluoroisopropyl
H
CF3


8-5142
3-cyanophenyl
H
Me
F
F
H
H
Br
H
heptafluoroisopropyl
H
CF3


8-5143
4-cyanophenyl
H
Me
F
F
H
H
Br
H
heptafluoroisopropyl
H
CF3


8-5158
2-chloropyridin-3-yl
H
Me
F
F
H
H
Br
H
heptafluoroisopropyl
H
CF3


8-5200
phenyl
H
Me
F
F
H
H
Br
H
nonafluoro-2-butyl
H
CF3


8-5220
3-cyanophenyl
H
Me
F
F
H
H
Br
H
nonafluoro-2-butyl
H
CF3


8-5221
4-cyanophenyl
H
Me
F
F
H
H
Br
H
nonafluoro-2-butyl
H
CF3


8-5236
2-chloropyridin-3-yl
H
Me
F
F
H
H
Br
H
nonafluoro-2-butyl
H
CF3


8-5278
phenyl
H
Me
F
F
H
H
I
H
heptafluoroisopropyl
H
CF3


8-5298
3-cyanophenyl
H
Me
F
F
H
H
I
H
heptafluoroisopropyl
H
CF3


8-5299
4-cyanophenyl
H
Me
F
F
H
H
I
H
heptafluoroisopropyl
H
CF3


8-5314
2-chloropyridin-3-yl
H
Me
F
F
H
H
I
H
heptafluoroisopropyl
H
CF3


8-5356
phenyl
H
Me
F
F
H
H
I
H
nonafluoro-2-butyl
H
CF3


8-5376
3-cyanophenyl
H
Me
F
F
H
H
I
H
nonafluoro-2-butyl
H
CF3


8-5377
4-cyanophenyl
H
Me
F
F
H
H
I
H
nonafluoro-2-butyl
H
CF3


8-5392
2-chloropyridin-3-yl
H
Me
F
F
H
H
I
H
nonafluoro-2-butyl
H
CF3


8-5434
phenyl
H
Me
F
F
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


8-5465
2-chloropyridin-3-yl
H
Me
F
F
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


8-5490
phenyl
H
Me
F
F
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


8-5521
2-chloropyridin-3-yl
H
Me
F
F
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


8-5546
phenyl
H
Me
F
F
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


8-5577
2-chloropyridin-3-yl
H
Me
F
F
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


8-5602
phenyl
H
Me
F
F
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


8-5633
2-chloropyridin-3-yl
H
Me
F
F
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


8-5678
3-cyanophenyl
H
Me
F
F
H
H
CF3
H
heptafluoroisopropyl
H
CF3


8-5679
4-cyanophenyl
H
Me
F
F
H
H
CF3
H
heptafluoroisopropyl
H
CF3


8-5694
2-chloropyridin-3-yl
H
Me
F
F
H
H
CF3
H
heptafluoroisopropyl
H
CF3


8-5726
phenyl
H
Me
F
F
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


8-5746
3-cyanophenyl
H
Me
F
F
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


8-5747
4-cyanophenyl
H
Me
F
F
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


8-5762
2-chloropyridin-3-yl
H
Me
F
F
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


8-5794
phenyl
H
Me
F
F
F
H
Cl
H
pentafluoroethyl
H
Cl


8-5795
phenyl
H
Me
F
F
F
H
Br
H
heptafluoroisopropyl
H
Br


8-5796
phenyl
H
Me
F
F
F
H
Br
H
heptafluoroisopropyl
H
OCF3


8-5797
phenyl
H
Me
F
F
F
H
I
H
heptafluoroisopropyl
H
CF3


8-5798
phenyl
H
Me
F
F
F
H
CF3
H
heptafluoroisopropyl
H
CF3


8-5799
phenyl
H
Me
F
F
F
H
I
H
nonafluoro-2-butyl
H
I


8-5800
phenyl
H
Me
F
F
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


8-5801
phenyl
H
Me
F
F
F
H
Br
H
nonafluoro-2-butyl
H
CF3


8-5802
phenyl
H
Me
F
F
F
H
CF3
H
nonafluoro-2-butyl
H
CF3


8-5803
phenyl
H
Me
H
H
F
H
Cl
H
pentafluoroethyl
H
Cl


8-5804
phenyl
H
Me
H
H
F
H
Br
H
heptafluoroisopropyl
H
Br


8-5805
phenyl
H
Me
H
H
F
H
Br
H
heptafluoroisopropyl
H
OCF3


8-5806
phenyl
H
Me
H
H
F
H
I
H
heptafluoroisopropyl
H
CF3


8-5807
phenyl
H
Me
H
H
F
H
CF3
H
heptafluoroisopropyl
H
CF3


8-5808
phenyl
H
Me
H
H
F
H
I
H
nonafluoro-2-butyl
H
I


8-5809
phenyl
H
Me
H
H
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


8-5810
phenyl
H
Me
H
H
F
H
Br
H
nonafluoro-2-butyl
H
CF3


8-5811
phenyl
H
Me
H
H
F
H
CF3
H
nonafluoro-2-butyl
H
CF3


8-5812
phenyl
H
Me
H
H
H
F
Cl
H
pentafluoroethyl
H
Cl


8-5813
phenyl
H
Me
H
H
H
F
Br
H
heptafluoroisopropyl
H
Br


8-5814
phenyl
H
Me
H
H
H
F
Br
H
heptafluoroisopropyl
H
OCF3


8-5815
phenyl
H
Me
H
H
H
F
I
H
heptafluoroisopropyl
H
CF3


8-5816
phenyl
H
Me
H
H
H
F
CF3
H
heptafluoroisopropyl
H
CF3


8-5817
phenyl
H
Me
H
H
H
F
I
H
nonafluoro-2-butyl
H
I


8-5818
phenyl
H
Me
H
H
H
F
Cl
H
nonafluoro-2-butyl
H
OCF3


8-5819
phenyl
H
Me
H
H
H
F
Br
H
nonafluoro-2-butyl
H
CF3


8-5820
phenyl
H
Me
H
H
H
F
CF3
H
nonafluoro-2-butyl
H
CF3


8-5821
phenyl
H
Me
F
H
F
H
Cl
H
pentafluoroethyl
H
Cl


8-5822
phenyl
H
Me
F
H
F
H
Br
H
heptafluoroisopropyl
H
Br


8-5823
phenyl
H
Me
F
H
F
H
Br
H
heptafluoroisopropyl
H
OCF3


8-5824
phenyl
H
Me
F
H
F
H
I
H
heptafluoroisopropyl
H
CF3


8-5825
phenyl
H
Me
F
H
F
H
CF3
H
heptafluoroisopropyl
H
CF3


8-5826
phenyl
H
Me
F
H
F
H
I
H
nonafluoro-2-butyl
H
I


8-5827
phenyl
H
Me
F
H
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


8-5828
phenyl
H
Me
F
H
F
H
Br
H
nonafluoro-2-butyl
H
CF3


8-5829
phenyl
H
Me
F
H
F
H
CF3
H
nonafluoro-2-butyl
H
CF3


8-5830
phenyl
H
Me
F
H
H
F
Cl
H
pentafluoroethyl
H
Cl


8-5831
phenyl
H
Me
F
H
H
F
Br
H
heptafluoroisopropyl
H
Br


8-5832
phenyl
H
Me
F
H
H
F
Br
H
heptafluoroisopropyl
H
OCF3


8-5833
phenyl
H
Me
F
H
H
F
I
H
heptafluoroisopropyl
H
CF3


8-5834
phenyl
H
Me
F
H
H
F
CF3
H
heptafluoroisopropyl
H
CF3


8-5835
phenyl
H
Me
F
H
H
F
I
H
nonafluoro-2-butyl
H
I


8-5836
phenyl
H
Me
F
H
H
F
Cl
H
nonafluoro-2-butyl
H
OCF3


8-5837
phenyl
H
Me
F
H
H
F
Br
H
nonafluoro-2-butyl
H
CF3


8-5838
phenyl
H
Me
F
H
H
F
CF3
H
nonafluoro-2-butyl
H
CF3


8-5839
phenyl
H
Me
H
F
F
H
Cl
H
pentafluoroethyl
H
Cl


8-5840
phenyl
H
Me
H
F
F
H
Br
H
heptafluoroisopropyl
H
Br


8-5841
phenyl
H
Me
H
F
F
H
Br
H
heptafluoroisopropyl
H
OCF3


8-5842
phenyl
H
Me
H
F
F
H
I
H
heptafluoroisopropyl
H
CF3


8-5843
phenyl
H
Me
H
F
F
H
CF3
H
heptafluoroisopropyl
H
CF3


8-5844
phenyl
H
Me
H
F
F
H
I
H
nonafluoro-2-butyl
H
I


8-5845
phenyl
H
Me
H
F
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


8-5846
phenyl
H
Me
H
F
F
H
Br
H
nonafluoro-2-butyl
H
CF3


8-5847
phenyl
H
Me
H
F
F
H
CF3
H
nonafluoro-2-butyl
H
CF3


8-5848
phenyl
H
Me
H
F
H
F
Cl
H
pentafluoroethyl
H
Cl


8-5849
phenyl
H
Me
H
F
H
F
Br
H
heptafluoroisopropyl
H
Br


8-5850
phenyl
H
Me
H
F
H
F
Br
H
heptafluoroisopropyl
H
OCF3


8-5851
phenyl
H
Me
H
F
H
F
I
H
heptafluoroisopropyl
H
CF3


8-5852
phenyl
H
Me
H
F
H
F
CF3
H
heptafluoroisopropyl
H
CF3


8-5853
phenyl
H
Me
H
F
H
F
I
H
nonafluoro-2-butyl
H
I


8-5854
phenyl
H
Me
H
F
H
F
Cl
H
nonafluoro-2-butyl
H
OCF3


8-5855
phenyl
H
Me
H
F
H
F
Br
H
nonafluoro-2-butyl
H
CF3


8-5856
phenyl
H
Me
H
F
H
F
CF3
H
nonafluoro-2-butyl
H
CF3


8-5857
phenyl
H
Me
H
H
F
F
Cl
H
pentafluoroethyl
H
Cl


8-5858
phenyl
H
Me
H
H
F
F
Br
H
heptafluoroisopropyl
H
Br


8-5859
phenyl
H
Me
H
H
F
F
Br
H
heptafluoroisopropyl
H
OCF3


8-5860
phenyl
H
Me
H
H
F
F
I
H
heptafluoroisopropyl
H
CF3


8-5861
phenyl
H
Me
H
H
F
F
CF3
H
heptafluoroisopropyl
H
CF3


8-5862
phenyl
H
Me
H
H
F
F
I
H
nonafluoro-2-butyl
H
I


8-5863
phenyl
H
Me
H
H
F
F
Cl
H
nonafluoro-2-butyl
H
OCF3


8-5864
phenyl
H
Me
H
H
F
F
Br
H
nonafluoro-2-butyl
H
CF3


8-5865
phenyl
H
Me
H
H
F
F
CF3
H
nonafluoro-2-butyl
H
CF3


8-5866
phenyl
H
Me
F
F
H
F
Cl
H
pentafluoroethyl
H
Cl


8-5867
phenyl
H
Me
F
F
H
F
Br
H
heptafluoroisopropyl
H
Br


8-5868
phenyl
H
Me
F
F
H
F
Br
H
heptafluoroisopropyl
H
OCF3


8-5869
phenyl
H
Me
F
F
H
F
I
H
heptafluoroisopropyl
H
CF3


8-5870
phenyl
H
Me
F
F
H
F
CF3
H
heptafluoroisopropyl
H
CF3


8-5871
phenyl
H
Me
F
F
H
F
I
H
nonafluoro-2-butyl
H
I


8-5872
phenyl
H
Me
F
F
H
F
Cl
H
nonafluoro-2-butyl
H
OCF3


8-5873
phenyl
H
Me
F
F
H
F
Br
H
nonafluoro-2-butyl
H
CF3


8-5874
phenyl
H
Me
F
F
H
F
CF3
H
nonafluoro-2-butyl
H
CF3


8-5875
phenyl
H
Me
F
H
F
F
Cl
H
pentafluoroethyl
H
Cl


8-5876
phenyl
H
Me
F
H
F
F
Br
H
heptafluoroisopropyl
H
Br


8-5877
phenyl
H
Me
F
H
F
F
Br
H
heptafluoroisopropyl
H
OCF3


8-5878
phenyl
H
Me
F
H
F
F
I
H
heptafluoroisopropyl
H
CF3


8-5879
phenyl
H
Me
F
H
F
F
CF3
H
heptafluoroisopropyl
H
CF3


8-5880
phenyl
H
Me
F
H
F
F
I
H
nonafluoro-2-butyl
H
I


8-5881
phenyl
H
Me
F
H
F
F
Cl
H
nonafluoro-2-butyl
H
OCF3


8-5882
phenyl
H
Me
F
H
F
F
Br
H
nonafluoro-2-butyl
H
CF3


8-5883
phenyl
H
Me
F
H
F
F
CF3
H
nonafluoro-2-butyl
H
CF3


8-5884
phenyl
H
Me
H
F
F
F
Cl
H
pentafluoroethyl
H
Cl


8-5885
phenyl
H
Me
H
F
F
F
Br
H
heptafluoroisopropyl
H
Br


8-5886
phenyl
H
Me
H
F
F
F
Br
H
heptafluoroisopropyl
H
OCF3


8-5887
phenyl
H
Me
H
F
F
F
I
H
heptafluoroisopropyl
H
CF3


8-5888
phenyl
H
Me
H
F
F
F
CF3
H
heptafluoroisopropyl
H
CF3


8-5889
phenyl
H
Me
H
F
F
F
I
H
nonafluoro-2-butyl
H
I


8-5890
phenyl
H
Me
H
F
F
F
Cl
H
nonafluoro-2-butyl
H
OCF3


8-5891
phenyl
H
Me
H
F
F
F
Br
H
nonafluoro-2-butyl
H
CF3


8-5892
phenyl
H
Me
H
F
F
F
CF3
H
nonafluoro-2-butyl
H
CF3


8-5893
phenyl
H
Me
F
F
F
F
Cl
H
pentafluoroethyl
H
Cl


8-5894
phenyl
H
Me
F
F
F
F
Br
H
heptafluoroisopropyl
H
Br


8-5895
phenyl
H
Me
F
F
F
F
Br
H
heptafluoroisopropyl
H
OCF3


8-5896
phenyl
H
Me
F
F
F
F
I
H
heptafluoroisopropyl
H
CF3


8-5897
phenyl
H
Me
F
F
F
F
CF3
H
heptafluoroisopropyl
H
CF3


8-5898
phenyl
H
Me
F
F
F
F
I
H
nonafluoro-2-butyl
H
I


8-5899
phenyl
H
Me
F
F
F
F
Cl
H
nonafluoro-2-butyl
H
OCF3


8-5900
phenyl
H
Me
F
F
F
F
Br
H
nonafluoro-2-butyl
H
CF3


8-5901
phenyl
H
Me
F
F
F
F
CF3
H
nonafluoro-2-butyl
H
CF3











embedded image





















TABLE 9





compound














number
Q1
R1
R2
X1
X2
X3
X4
Y1
Y2
Y3
Y4
Y5







9-1
phenyl
Me
Me
H
H
H
H
F
H
nonafluoro-2-butyl
H
F


9-2
3-cyanophenyl
Me
Me
H
H
H
H
F
H
nonafluoro-2-butyl
H
F


9-3
4-cyanophenyl
Me
Me
H
H
H
H
F
H
nonafluoro-2-butyl
H
F


9-4
2-chloropyridin-3-yl
Me
Me
H
H
H
H
F
H
nonafluoro-2-butyl
H
F


9-5
phenyl
Me
Me
H
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


9-12
3-cyanophenyl
Me
Me
H
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


9-13
4-cyanophenyl
Me
Me
H
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


9-24
2-chloropyridin-3-yl
Me
Me
H
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


9-38
phenyl
Me
Me
H
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


9-45
3-cyanophenyl
Me
Me
H
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


9-46
4-cyanophenyl
Me
Me
H
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


9-57
2-chloropyridin-3-yl
Me
Me
H
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


9-71
phenyl
Me
Me
H
H
H
H
I
H
nonafluoro-2-butyl
H
I


9-78
3-cyanophenyl
Me
Me
H
H
H
H
I
H
nonafluoro-2-butyl
H
I


9-79
4-cyanophenyl
Me
Me
H
H
H
H
I
H
nonafluoro-2-butyl
H
I


9-90
2-chloropyridin-3-yl
Me
Me
H
H
H
H
I
H
nonafluoro-2-butyl
H
I


9-109
phenyl
Me
Me
H
H
H
H
Cl
H
nonafluoro-2-butyl
H
Br


9-112
phenyl
Me
Me
H
H
H
H
F
H
heptafluoroisopropyl
H
CF3


9-113
phenyl
Me
Me
H
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


9-133
3-cyanophenyl
Me
Me
H
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


9-134
4-cyanophenyl
Me
Me
H
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


9-149
2-chloropyridin-3-yl
Me
Me
H
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


9-191
phenyl
Me
Me
H
H
H
H
F
H
nonafluoro-2-butyl
H
CF3


9-192
phenyl
Me
Me
H
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


9-212
3-cyanophenyl
Me
Me
H
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


9-213
4-cyanophenyl
Me
Me
H
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


9-228
2-chloropyridin-3-yl
Me
Me
H
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


9-270
phenyl
Me
Me
H
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


9-290
3-cyanophenyl
Me
Me
H
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


9-291
4-cyanophenyl
Me
Me
H
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


9-306
2-chloropyridin-3-yl
Me
Me
H
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


9-348
phenyl
Me
Me
H
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


9-368
3-cyanophenyl
Me
Me
H
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


9-369
4-cyanophenyl
Me
Me
H
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


9-384
2-chloropyridin-3-yl
Me
Me
H
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


9-426
phenyl
Me
Me
H
H
H
H
I
H
heptafluoroisopropyl
H
CF3


9-446
3-cyanophenyl
Me
Me
H
H
H
H
I
H
heptafluoroisopropyl
H
CF3


9-447
4-cyanophenyl
Me
Me
H
H
H
H
I
H
heptafluoroisopropyl
H
CF3


9-462
2-chloropyridin-3-yl
Me
Me
H
H
H
H
I
H
heptafluoroisopropyl
H
CF3


9-504
phenyl
Me
Me
H
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-524
3-cyanophenyl
Me
Me
H
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-525
4-cyanophenyl
Me
Me
H
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-540
2-chloropyridin-3-yl
Me
Me
H
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-778
phenyl
Me
Me
H
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


9-809
2-chloropyridin-3-yl
Me
Me
H
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


9-834
phenyl
Me
Me
H
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


9-865
2-chloropyridin-3-yl
Me
Me
H
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


9-890
phenyl
Me
Me
H
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


9-921
2-chloropyridin-3-yl
Me
Me
H
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


9-946
phenyl
Me
Me
H
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


9-977
2-chloropyridin-3-yl
Me
Me
H
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


9-1002
phenyl
Me
Me
H
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


9-1022
3-cyanophenyl
Me
Me
H
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


9-1023
4-cyanophenyl
Me
Me
H
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


9-1038
2-chloropyridin-3-yl
Me
Me
H
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


9-1070
phenyl
Me
Me
H
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


9-1090
3-cyanophenyl
Me
Me
H
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


9-1091
4-cyanophenyl
Me
Me
H
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


9-1106
2-chloropyridin-3-yl
Me
Me
H
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


9-1334
phenyl
Me
Me
F
H
H
H
F
H
heptafluoroisopropyl
H
F


9-1335
3-cyanophenyl
Me
Me
F
H
H
H
F
H
heptafluoroisopropyl
H
F


9-1336
4-cyanophenyl
Me
Me
F
H
H
H
F
H
heptafluoroisopropyl
H
F


9-1337
2-chloropyridin-3-yl
Me
Me
F
H
H
H
F
H
heptafluoroisopropyl
H
F


9-1338
phenyl
Me
Me
F
H
H
H
F
H
nonafluoro-2-butyl
H
F


9-1339
3-cyanophenyl
Me
Me
F
H
H
H
F
H
nonafluoro-2-butyl
H
F


9-1340
4-cyanophenyl
Me
Me
F
H
H
H
F
H
nonafluoro-2-butyl
H
F


9-1341
2-chloropyridin-3-yl
Me
Me
F
H
H
H
F
H
nonafluoro-2-butyl
H
F


9-1342
phenyl
Me
Me
F
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


9-1362
3-cyanophenyl
Me
Me
F
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


9-1363
4-cyanophenyl
Me
Me
F
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


9-1378
2-chloropyridin-3-yl
Me
Me
F
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


9-1420
phenyl
Me
Me
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


9-1440
3-cyanophenyl
Me
Me
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


9-1441
4-cyanophenyl
Me
Me
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


9-1456
2-chloropyridin-3-yl
Me
Me
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


9-1498
phenyl
Me
Me
F
H
H
H
Br
H
heptafluoroisopropyl
H
Br


9-1518
3-cyanophenyl
Me
Me
F
H
H
H
Br
H
heptafluoroisopropyl
H
Br


9-1519
4-cyanophenyl
Me
Me
F
H
H
H
Br
H
heptafluoroisopropyl
H
Br


9-1534
2-chloropyridin-3-yl
Me
Me
F
H
H
H
Br
H
heptafluoroisopropyl
H
Br


9-1576
phenyl
Me
Me
F
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


9-1596
3-cyanophenyl
Me
Me
F
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


9-1597
4-cyanophenyl
Me
Me
F
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


9-1612
2-chloropyridin-3-yl
Me
Me
F
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


9-1654
phenyl
Me
Me
F
H
H
H
I
H
heptafluoroisopropyl
H
I


9-1674
3-cyanophenyl
Me
Me
F
H
H
H
I
H
heptafluoroisopropyl
H
I


9-1675
4-cyanophenyl
Me
Me
F
H
H
H
I
H
heptafluoroisopropyl
H
I


9-1690
2-chloropyridin-3-yl
Me
Me
F
H
H
H
I
H
heptafluoroisopropyl
H
I


9-1732
phenyl
Me
Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
I


9-1752
3-cyanophenyl
Me
Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
I


9-1753
4-cyanophenyl
Me
Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
I


9-1768
2-chloropyridin-3-yl
Me
Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
I


9-2006
phenyl
Me
Me
F
H
H
H
F
H
heptafluoroisopropyl
H
CF3


9-2007
phenyl
Me
Me
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


9-2019
4-iodophenyl
Me
Et
F
H
H
H
Cl
H
pentafluoroethyl
H
CF3


9-2021
(3-trifluoromethyl) phenyl
Et
Me
F
H
H
H
Cl
H
heptafluoroisopropyl
H
C2F5


9-2027
3-cyanophenyl
Me
Me
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


9-2028
4-cyanophenyl
Me
Me
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


9-2030
3,4-dichlorophenyl
Me
n-Pr
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


9-2032
2-chloro-4-fluorophenyl
n-Pr
Me
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


9-2043
2-chloropyridin-3-yl
Me
Me
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


9-2047
2-nitropyridin-3-yl
Me
i-Pr
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


9-2049
6-fluoropyridin-3-yl
i-Pr
Me
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


9-2063
4-fluoropyridin-3-yl
Me
CH2CH═CH2
F
H
H
H
Cl
H
pentafluoroethyl
H
CF3


9-2065
4-bromopyridin-3-yl
CH2CH═CH2
Me
F
H
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F67


9-2070
2,6-dichloropyridin-3-yl
Me
CN
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


9-2072
pyridin-4-yl
CN
Me
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


9-2085
phenyl
Me
Me
F
H
H
H
F
H
nonafluoro-2-butyl
H
CF3


9-2086
phenyl
Me
Me
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


9-2092
4-chlorophenyl
Me
CH2C≡CH
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


9-2094
3-bromophenyl
CH2C≡CH
Me
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


9-2099
(2-trifluoromethyl) phenyl
Me
NH2
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


9-2101
(4-trifluoromethyl) phenyl
NH2
Me
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


9-2106
3-cyanophenyl
Me
Me
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


9-2107
4-cyanophenyl
Me
Me
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


9-2112
2-chloro-4,5-difluorophenyl
Me
C(O)OMe
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


9-2114
2-bromo-4-chlorophenyl
C(O)OMe
Me
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


9-2122
2-chloropyridin-3-yl
Me
Me
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


9-2133
6-nitropyridin-3-yl
Me
C(O)OEt
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


9-2135
5-fluoropyridin-3-yl
C(O)OEt
Me
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


9-2142
4-fluoropyridin-3-yl
Me
C(O)C(O)Me
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


9-2144
4-bromopyridin-3-yl
C(O)C(O)Me
Me
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


9-2145
4-iodopyridin-3-yl
Me
C(O)C(O)Et
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


9-2147
4-nitropyridin-3-yl
C(O)C(O)Et
Me
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


9-2156
2,6-dicyanopyridin-4-yl
Me
C(O)Et
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


9-2159
3-chloropyridin-2-yl
Me
C(O)Me
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


9-2161
5-iodopyridin-2-yl
C(O)Me
Me
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


9-2163
4-cyanopyridin-2-yl
C(O)Et
Me
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


9-2164
phenyl
Me
Me
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


9-2176
4-iodophenyl
Me
S(O)2Me
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


9-2178
(3-trifluoromethyl) phenyl
S(O)2Me
Me
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


9-2184
3-cyanophenyl
Me
Me
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


9-2185
4-cyanophenyl
Me
Me
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


9-2194
2-chloro-4-nitrophenyl
Me
S(O)2Et
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


9-2196
4-cyano-2-fluorophenyl
S(O)2Et
Me
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


9-2200
2-chloropyridin-3-yl
Me
Me
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


9-2209
6-iodopyridin-3-yl
Me
CH2Ph
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


9-2211
6-nitropyridin-3-yl
CH2Ph
Me
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


9-2218
5-nitropyridin-3-yl
Me
CH2(3-Py)
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


9-2220
4-fluoropyridin-3-yl
CH2(3-Py)
Me
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


9-2239
5-iodopyridin-2-yl
Me
CH2(3-Py—N-
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3





oxide)











9-2241
4-cyanopyridin-2-yl
CH2(3-Py—N-
Me
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3




oxide)












9-2242
phenyl
Me
Me
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


9-2262
3-cyanophenyl
Me
Me
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


9-2263
4-cyanophenyl
Me
Me
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


9-2267
2-chloro-4-fluorophenyl
Me
Et
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


9-2269
4-bromo-2-chlorophenyl
Et
Me
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


9-2278
2-chloropyridin-3-yl
Me
Me
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


9-2293
5-bromopyridin-3-yl
Me
CN
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


9-2295
5-(fluoromethyl) pyridin-3-yl
CN
Me
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


9-2320
phenyl
Me
Me
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


9-2322
3-fluorophenyl
Me
Me
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


9-2340
3-cyanophenyl
Me
Me
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


9-2341
4-cyanophenyl
Me
Me
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


9-2356
2-chloropyridin-3-yl
Me
Me
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


9-2367
6-nitropyridin-3-yl
Me
C(O)Me
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


9-2369
5-fluoropyridin-3-yl
C(O)Me
Me
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


9-2398
phenyl
Me
Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2418
3-cyanophenyl
Me
Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2419
4-cyanophenyl
Me
Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2434
2-chloropyridin-3-yl
Me
Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2476
phenyl
Et
Et
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2477
phenyl
Et
n-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2478
phenyl
Et
i-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2479
phenyl
Et
CH2CH═CH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2480
phenyl
Et
CN
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2481
phenyl
Et
CH2C≡CH
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2482
phenyl
Et
NH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2483
phenyl
Et
C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2484
phenyl
Et
C(O)C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2485
phenyl
Et
C(O)Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2486
phenyl
Et
S(O)2Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2487
phenyl
Et
CH2Ph
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2488
phenyl
Et
CH2(3-Py)
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2489
phenyl
Et
CH2(3-Py—N-
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3





oxide)
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2490
phenyl
n-Pr
Et
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2491
phenyl
n-Pr
n-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2492
phenyl
n-Pr
i-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2493
phenyl
n-Pr
CH2CH═CH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2494
phenyl
n-Pr
CN
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2495
phenyl
n-Pr
CH2C≡CH
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2496
phenyl
n-Pr
NH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2497
phenyl
n-Pr
C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2498
phenyl
n-Pr
C(O)C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2499
phenyl
n-Pr
C(O)Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2500
phenyl
n-Pr
S(O)2Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2501
phenyl
n-Pr
CH2Ph
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2502
phenyl
n-Pr
CH2(3-Py)
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2503
phenyl
n-Pr
CH2(3-Py—N-
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3





oxide)











9-2504
phenyl
i-Pr
Et
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2505
phenyl
i-Pr
n-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2506
phenyl
i-Pr
i-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2507
phenyl
i-Pr
CH2CH═CH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2508
phenyl
i-Pr
CN
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2509
phenyl
i-Pr
CH2C≡CH
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2510
phenyl
i-Pr
NH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2511
phenyl
i-Pr
C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2512
phenyl
i-Pr
C(O)C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2513
phenyl
i-Pr
C(O)Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2514
phenyl
i-Pr
S(O)2Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2515
phenyl
i-Pr
CH2Ph
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2516
phenyl
i-Pr
CH2(3-Py)
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2517
phenyl
i-Pr
CH2(3-Py—N-
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3





oxide)











9-2518
phenyl
CH2CH═CH2
Et
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2519
phenyl
CH2CH═CH2
n-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2520
phenyl
CH2CH═CH2
i-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2521
phenyl
CH2CH═CH2
CH2CH=CH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2522
phenyl
CH2CH═CH2
CN
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2523
phenyl
CH2CH═CH2
CH2C≡CH
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2524
phenyl
CH2CH═CH2
NH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2525
phenyl
CH2CH═CH2
C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2526
phenyl
CH2CH═CH2
C(O)C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2527
phenyl
CH2CH═CH2
C(O)Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2528
phenyl
CH2CH═CH2
C(O)2Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2529
phenyl
CH2CH═CH2
CH2Ph
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2530
phenyl
CH2CH═CH2
CH2(3-Py)
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2531
phenyl
CH2CH═CH2
CH2(3-Py—N-
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3





oxide)











9-2532
phenyl
CN
Et
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2533
phenyl
CN
n-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2534
phenyl
CN
i-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2535
phenyl
CN
CH2CH═CH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2536
phenyl
CN
CN
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2537
phenyl
CN
CH2C≡CH
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2538
phenyl
CN
NH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2539
phenyl
CN
C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2540
phenyl
CN
C(O)C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2541
phenyl
CN
C(O)Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2542
phenyl
CN
S(O)2Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2543
phenyl
CN
CH2Ph
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2544
phenyl
CN
CH2(3-Py)
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2545
phenyl
CN
CH2(3-Py—N-
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3





oxide)











9-2546
phenyl
CH2C≡CH
Et
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2547
phenyl
CH2C≡CH
n-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2548
phenyl
CH2C≡CH
i-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2549
phenyl
CH2C≡CH
CH2CH═CH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2550
phenyl
CH2C≡CH
CN
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2551
phenyl
CH2C≡CH
CH2C≡CH
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2552
phenyl
CH2C≡CH
NH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2553
phenyl
CH2C≡CH
C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2554
phenyl
CH2C≡CH
C(O)C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2555
phenyl
CH2C≡CH
C(O)Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2556
phenyl
CH2C≡CH
S(O)2Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2557
phenyl
CH2C≡CH
CH2Ph
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2558
phenyl
CH2C≡CH
CH2(3-Py)
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2559
phenyl
CH2C≡CH
CH2(3-Py—N-
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3





oxide)











9-2560
phenyl
NH2
Et
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2561
phenyl
NH2
n-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2562
phenyl
NH2
i-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2563
phenyl
NH2
CH2CH═CH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2564
phenyl
NH2
CN
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2565
phenyl
NH2
CH2C≡CH
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2566
phenyl
NH2
NH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2567
phenyl
NH2
C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2568
phenyl
NH2
C(O)C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2569
phenyl
NH2
C(O)Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2570
phenyl
NH2
S(O)2Me
F
H
H
H
I
H
nonafluoro-2-butyl
FI
CF3


9-2571
phenyl
NH2
CH2Ph
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2572
phenyl
NH2
CH2(3-Py)
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2573
phenyl
NH2
CH2(3-Py—N-
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3





oxide)











9-2574
phenyl
C(O)OMe
Et
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2575
phenyl
C(O)OMe
n-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2576
phenyl
C(O)OMe
i-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2577
phenyl
C(O)OMe
CH2CH=CH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2578
phenyl
C(O)OMe
CN
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2579
phenyl
C(O)OMe
CH2C≡CH
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2580
phenyl
C(O)OMe
NH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2581
phenyl
C(O)OMe
C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2582
phenyl
C(O)OMe
C(O)C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2583
phenyl
C(O)OMe
C(O)Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2584
phenyl
C(O)OMe
S(O)2Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2585
phenyl
C(O)OMe
CH2Ph
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2586
phenyl
C(O)OMe
CH2(3-Py)
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2587
phenyl
C(O)OMe
CH2(3-Py—N-
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3





oxide)











9-2588
phenyl
C(O)C(O)OMe
Et
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2589
phenyl
C(O)C(O)OMe
n-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2590
phenyl
C(O)C(O)OMe
i-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2591
phenyl
C(O)C(O)OMe
CH2CH=CH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2592
phenyl
C(O)C(O)OMe
CN
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2593
phenyl
C(O)C(O)OMe
CH2C≡CH
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2594
phenyl
C(O)C(O)OMe
NH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2595
phenyl
C(O)C(O)OMe
C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2596
phenyl
C(O)C(O)OMe
C(O)C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2597
phenyl
C(O)C(O)OMe
C(O)Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2598
phenyl
C(O)C(O)OMe
S(O)2Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2599
phenyl
C(O)C(O)OMe
CH2Ph
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2600
phenyl
C(O)C(O)OMe
CH2(3-Py)
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2601
phenyl
C(O)C(O)OMe
CH2(3-Py—N-
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3





oxide)











9-2602
phenyl
C(O)Me
Et
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2603
phenyl
C(O)Me
n-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2604
phenyl
C(O)Me
i-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2605
phenyl
C(O)Me
CH2CH=CH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2606
phenyl
C(O)Me
CN
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2607
phenyl
C(O)Me
CH2C≡CH
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2608
phenyl
C(O)Me
NH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2609
phenyl
C(O)Me
C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2610
phenyl
C(O)Me
C(O)C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2611
phenyl
C(O)Me
C(O)Me
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


9-2612
phenyl
C(O)Me
S(O)2Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2613
phenyl
C(O)Me
CH2Ph
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2614
phenyl
C(O)Me
CH2(3-Py)
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2615
phenyl
C(O)Me
CH2(3-Py—N-
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3





oxide)






nonafluoro-2-butyl
H
CF3


9-2616
phenyl
S(O)2Me
Et
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2617
phenyl
S(O)2Me
n-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2618
phenyl
S(O)2Me
i-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2619
phenyl
S(O)2Me
CH2CH=CH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2620
phenyl
S(O)2Me
CN
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2621
phenyl
S(O)2Me
CH2C≡CH
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2622
phenyl
S(O)2Me
NH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2623
phenyl
S(O)2Me
C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2624
phenyl
S(O)2Me
C(O)C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2625
phenyl
S(O)2Me
C(O)Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2626
phenyl
S(O)2Me
S(O)2Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2627
phenyl
S(O)2Me
CH2Ph
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2628
phenyl
S(O)2Me
CH2(3-Py)
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2629
phenyl
S(O)2Me
CH2(3-Py—N-
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3





oxide)











9-2630
phenyl
CH2Ph
Et
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2631
phenyl
CH2Ph
n-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2632
phenyl
CH2Ph
i-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2633
phenyl
CH2Ph
CH2CH═CH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2634
phenyl
CH2Ph
CN
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2635
phenyl
CH2Ph
CH2C≡CH
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2636
phenyl
CH2Ph
NH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2637
phenyl
CH2Ph
C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2638
phenyl
CH2Ph
C(O)C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2639
phenyl
CH2Ph
C(O)Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2640
phenyl
CH2Ph
S(O)2Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2641
phenyl
CH2Ph
CH2Ph
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2642
phenyl
CH2P8
CH2(3-Py)
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2643
phenyl
CH2Ph
CH2(3-Py—N-
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3





oxide)











9-2644
phenyl
CH2(3-Py)
Et
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2645
phenyl
CH2(3-Py)
n-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2646
phenyl
CH2(3-Py)
i-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2647
phenyl
CH2(3-Py)
CH2C=H2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2648
phenyl
CH2(3-Py)
CN
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2649
phenyl
CH2(3-Py)
CH2C = CH
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2650
phenyl
CH2(3-Py)
NH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2651
phenyl
CH2(3-Py)
C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2652
phenyl
CH2(3-Py)
C(O)C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2653
phenyl
CH2(3-Py)
C(O)Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2654
phenyl
CH2(3-Py)
S(O)2Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2655
phenyl
CH2(3-Py)
CH2Ph
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2656
phenyl
CH2(3-Py)
CH2(3-Py)
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-2657
phenyl
CH2(3-Py)
CH2(3-Py—N-
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3





oxide)











9-2658
phenyl
CH2(3-Py—N-
Et
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3




oxide)












9-2659
phenyl
CH2(3-Py—N-
n-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3




oxide)












9-2660
phenyl
CH2(3-Py—N-
i-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3




oxide)












9-2661
phenyl
CH2(3-Py—N-
CH2CH═CH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3




oxide)












9-2662
phenyl
CH2(3-Py—N-
CN
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3




oxide)












9-2663
phenyl
CH2(3-Py—N-
CH2C≡CH
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3




oxide)












9-2664
phenyl
CH2(3-Py—N-
NH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3




oxide)












9-2665
phenyl
CH2(3-Py—N-
C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3




oxide)












9-2666
phenyl
CH2(3-Py—N-
C(O)C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3




oxide)












9-2667
phenyl
CH2(3-Py—N-
C(O)Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3




oxide)












9-2668
phenyl
CH2(3-Py—N-
S(O)2Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3




oxide)












9-2669
phenyl
CH2(3-Py—N-
CH2Ph
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3




oxide)












9-2670
phenyl
CH2(3-Py—N-
CH2(3-Py)
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3




oxide)












9-2671
phenyl
CH2(3-Py—N-
CH2(3-Py—N-
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3




oxide)
oxide)











9-2672
phenyl
Me
Me
F
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


9-2687
3-cyanophenyl
Me
Me
F
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


9-2688
4-cyanophenyl
Me
Me
F
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


9-2703
2-chloropyridin-3-yl
Me
Me
F
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


9-2728
phenyl
Me
Me
F
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


9-2743
3-cyanophenyl
Me
Me
F
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


9-2744
4-cyanophenyl
Me
Me
F
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


9-2759
2-chloropyridin-3-yl
Me
Me
F
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


9-2784
phenyl
Me
Me
F
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


9-2799
3-cyanophenyl
Me
Me
F
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


9-2800
4-cyanophenyl
Me
Me
F
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


9-2815
2-chloropyridin-3-yl
Me
Me
F
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


9-2840
phenyl
Me
Me
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


9-2855
3-cyanophenyl
Me
Me
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


9-2856
4-cyanophenyl
Me
Me
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


9-2871
2-chloropyridin-3-yl
Me
Me
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


9-2896
phenyl
Me
Me
F
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


9-2916
3-cyanophenyl
Me
Me
F
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


9-2917
4-cyanophenyl
Me
Me
F
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


9-2932
2-chloropyridin-3-yl
Me
Me
F
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


9-2964
phenyl
Me
Me
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


9-2984
3-cyanophenyl
Me
Me
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


9-2985
4-cyanophenyl
Me
Me
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


9-3000
2-chloropyridin-3-yl
Me
Me
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


9-3228
phenyl
Me
Me
H
F
H
H
F
H
heptafluoroisopropyl
H
F


9-3229
3-cyanophenyl
Me
Me
H
F
H
H
F
H
heptafluoroisopropyl
H
F


9-3230
4-cyanophenyl
Me
Me
H
F
H
H
F
H
heptafluoroisopropyl
H
F


9-3231
2-chloropyridin-3-yl
Me
Me
H
F
H
H
F
H
heptafluoroisopropyl
H
F


9-3232
phenyl
Me
Me
H
F
H
H
F
H
nonafluoro-2-butyl
H
F


9-3233
3-cyanophenyl
Me
Me
H
F
H
H
F
H
nonafluoro-2-butyl
H
F


9-3234
4-cyanophenyl
Me
Me
H
F
H
H
F
H
nonafluoro-2-butyl
H
F


9-3235
2-chloropyridin-3-yl
Me
Me
H
F
H
H
F
H
nonafluoro-2-butyl
H
F


9-3236
phenyl
Me
Me
H
F
H
H
Cl
H
heptafluoroisopropyl
H
Cl


9-3256
3-cyanophenyl
Me
Me
H
F
H
H
Cl
H
heptafluoroisopropyl
H
Cl


9-3257
4-cyanophenyl
Me
Me
H
F
H
H
Cl
H
heptafluoroisopropyl
H
Cl


9-3272
2-chloropyridin-3-yl
Me
Me
H
F
H
H
Cl
H
heptafluoroisopropyl
H
Cl


9-3314
phenyl
Me
Me
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


9-3334
3-cyanophenyl
Me
Me
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


9-3335
4-cyanophenyl
Me
Me
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


9-3350
2-chloropyridin-3-yl
Me
Me
H
F
F
H
Cl
H
nonafluoro-2-butyl
H
Cl


9-3392
phenyl
Me
Me
H
F
H
H
Br
H
heptafluoroisopropyl
H
Br


9-3412
3-cyanophenyl
Me
Me
H
F
H
H
Br
H
heptafluoroisopropyl
H
Br


9-3413
4-cyanophenyl
Me
Me
H
F
H
H
Br
H
heptafluoroisopropyl
H
Br


9-3428
2-chloropyridin-3-yl
Me
Me
H
F
H
H
Br
H
heptafluoroisopropyl
H
Br


9-3470
phenyl
Me
Me
H
F
H
H
Br
H
nonafluoro-2-butyl
H
Br


9-3490
3-cyanophenyl
Me
Me
H
F
H
H
Br
H
nonafluoro-2-butyl
H
Br


9-3491
4-cyanophenyl
Me
Me
H
F
H
H
Br
H
nonafluoro-2-butyl
H
Br


9-3506
2-chloropyridin-3-yl
Me
Me
H
F
H
H
Br
H
nonafluoro-2-butyl
H
Br


9-3548
phenyl
Me
Me
H
F
H
H
I
H
heptafluoroisopropyl
H
I


9-3568
3-cyanophenyl
Me
Me
H
F
H
H
I
H
heptafluoroisopropyl
H
I


9-3569
4-cyanophenyl
Me
Me
H
F
H
H
I
H
heptafluoroisopropyl
H
I


9-3584
2-chloropyridin-3-yl
Me
Me
H
F
H
H
I
H
heptafluoroisopropyl
H
I


9-3626
phenyl
Me
Me
H
F
H
H
I
H
nonafluoro-2-butyl
H
I


9-3646
3-cyanophenyl
Me
Me
H
F
H
H
I
H
nonafluoro-2-butyl
H
I


9-3647
4-cyanophenyl
Me
Me
H
F
H
H
I
H
nonafluoro-2-butyl
H
I


9-3662
2-chloropyridin-3-yl
Me
Me
H
F
H
H
I
H
nonafluoro-2-butyl
H
I


9-3900
phenyl
Me
Me
H
F
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


9-3920
3-cyanophenyl
Me
Me
H
F
H
H
Cl
Cl
heptafluoroisopropyl
H
OCF3


9-3921
4-cyanophenyl
Me
Me
H
F
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


9-3936
2-chloropyridin-3-yl
Me
Me
H
F
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


9-3978
phenyl
Me
Me
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


9-3998
3-cyanophenyl
Me
Me
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


9-3999
4-cyanophenyl
Me
Me
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


9-4014
2-chloropyridin-3-yl
Me
Me
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


9-4056
phenyl
Me
Me
H
F
H
H
Br
H
heptafluoroisopropyl
H
OCF3


9-4076
3-cyanophenyl
Me
Me
H
F
H
H
Br
H
heptafluoroisopropyl
H
OCF3


9-4077
4-cyanophenyl
Me
Me
H
F
H
H
Br
H
heptafluoroisopropyl
H
OCF3


9-4092
2-chloropyridin-3-yl
Me
Me
H
F
H
H
Br
H
heptafluoroisopropyl
H
OCF3


9-4134
phenyl
Me
Me
H
F
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


9-4154
3-cyanophenyl
Me
Me
H
F
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


9-4155
4-cyanophenyl
Me
Me
H
F
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


9-4170
2-chloropyridin-3-yl
Me
Me
H
F
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


9-4212
phenyl
Me
Me
H
F
H
H
I
H
heptafluoroisopropyl
H
OCF3


9-4232
3-cyanophenyl
Me
Me
H
F
H
H
I
H
heptafluoroisopropyl
H
OCF3


9-4233
4-cyanophenyl
Me
Me
H
F
H
H
I
H
heptafluoroisopropyl
H
OCF3


9-4248
2-chloropyridin-3-yl
Me
Me
H
F
H
H
I
H
heptafluoroisopropyl
H
OCF3


9-4290
phenyl
Me
Me
H
F
H
H
I
H
nonafluoro-2-butyl
H
OCF3


9-4310
3-cyanophenyl
Me
Me
H
F
H
H
I
H
nonafluoro-2-butyl
H
OCF3


9-4311
4-cyanophenyl
Me
Me
H
F
H
H
I
H
nonafluoro-2-butyl
H
OCF3


9-4326
2-chloropyridin-3-yl
Me
Me
H
F
H
H
I
H
nonafluoro-2-butyl
H
OCF3


9-4564
phenyl
Me
Me
H
F
H
H
F
H
heptafluoroisopropyl
H
CF3


9-4565
phenyl
Me
Me
H
F
H
H
Cl
H
heptafluoroisopropyl
H
CF3


9-4585
3-cyanophenyl
Me
Me
H
F
H
H
Cl
H
heptafluoroisopropyl
H
CF3


9-4586
4-cyanophenyl
Me
Me
H
F
H
H
Cl
H
heptafluoroisopropyl
H
CF3


9-4601
2-chloropyridin-3-yl
Me
Me
H
F
H
H
Cl
H
heptafluoroisopropyl
H
CF3


9-4643
phenyl
Me
Me
H
F
H
H
F
H
nonafluoro-2-butyl
H
CF3


9-4644
phenyl
Me
Me
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


9-4664
3-cyanophenyl
Me
Me
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


9-4665
4-cyanophenyl
Me
Me
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


9-4680
2-chloropyridin-3-yl
Me
Me
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


9-4722
phenyl
Me
Me
H
F
H
H
Br
H
heptafluoroisopropyl
H
CF3


9-4742
3-cyanophenyl
Me
Me
H
F
H
H
Br
H
heptafluoroisopropyl
H
CF3


9-4743
4-cyanophenyl
Me
Me
H
F
H
H
Br
H
heptafluoroisopropyl
H
CF3


9-4758
2-chloropyridin-3-yl
Me
Me
H
F
H
H
Br
H
heptafluoroisopropyl
H
CF3


9-4800
phenyl
Me
Me
H
F
H
H
Br
H
nonafluoro-2-butyl
H
CF3


9-4820
3-cyanophenyl
Me
Me
H
F
H
H
Br
H
nonafluoro-2-butyl
FI
CF3


9-4821
4-cyanophenyl
Me
Me
H
F
H
H
Br
H
nonafluoro-2-butyl
H
CF3


9-4836
2-chloropyridin-3-yl
Me
Me
H
F
H
H
Br
H
nonafluoro-2-butyl
H
CF3


9-4878
phenyl
Me
Me
H
F
H
H
I
H
heptafluoroisopropyl
H
CF3


9-4898
3-cyanophenyl
Me
Me
H
F
H
H
I
H
heptafluoroisopropyl
H
CF3


9-4899
4-cyanophenyl
Me
Me
H
F
H
H
I
H
heptafluoroisopropyl
H
CF3


9-4914
2-chloropyridin-3-yl
Me
Me
H
F
H
H
I
H
heptafluoroisopropyl
H
CF3


9-4956
phenyl
Me
Me
H
F
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-4976
3-cyanophenyl
Me
Me
H
F
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-4977
4-cyanophenyl
Me
Me
H
F
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-4992
2-chloropyridin-3-yl
Me
Me
H
F
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-5230
phenyl
Me
Me
H
F
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


9-5261
2-chloropyridin-3-yl
Me
Me
H
F
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


9-5286
phenyl
Me
Me
H
F
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


9-5317
2-chloropyridin-3-yl
Me
Me
H
F
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


9-5342
phenyl
Me
Me
H
F
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


9-5373
2-chloropyridin-3-yl
Me
Me
H
F
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


9-5398
phenyl
Me
Me
H
F
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


9-5429
2-chloropyridin-3-yl
Me
Me
H
F
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


9-5454
phenyl
Me
Me
H
F
H
H
CF3
H
heptafluoroisopropyl
H
CF3


9-5474
3-cyanophenyl
Me
Me
H
F
H
H
CF3
H
heotafluoroisopropyl
H
CF3


9-5475
4-cyanophenyl
Me
Me
H
F
H
H
CF3
H
heptafluoroisopropyl
H
CF3


9-5490
2-chloropyridin-3-yl
Me
Me
H
F
H
H
CF3
H
heptafluoroisopropyl
H
CF3


9-5522
phenyl
Me
Me
H
F
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


9-5542
3-cyanophenyl
Me
Me
H
F
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


9-5543
4-cyanophenyl
Me
Me
H
F
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


9-5558
2-chloropyridin-3-yl
Me
Me
H
F
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


9-5786
phenyl
Me
Me
F
F
H
H
F
H
heptafluoroisopropyl
H
F


9-5787
3-cyanophenyl
Me
Me
F
F
H
H
F
H
heptafluoroisopropyl
H
F


9-5788
4-cyanophenyl
Me
Me
F
F
H
H
F
H
heptafluoroisopropyl
H
F


9-5789
2-chloropyridin-3-yl
Me
Me
F
F
H
H
F
H
heptafluoroisopropyl
H
F


9-5790
phenyl
Me
Me
F
F
H
H
F
H
nonafluoro-2-butyl
H
F


9-5791
3-cyanophenyl
Me
Me
F
F
H
H
F
H
nonafluoro-2-butyl
H
F


9-5792
4-cyanophenyl
Me
Me
F
F
H
H
F
H
nonafluoro-2-butyl
H
F


9-5793
2-chloropyridin-3-yl
Me
Me
F
F
H
H
F
H
nonafluoro-2-butyl
H
F


9-5794
phenyl
Me
Me
F
F
H
H
Cl
H
heptafluoroisopropyl
H
Cl


9-5814
3-cyanophenyl
Me
Me
F
F
H
H
Cl
H
heptafluoroisopropyl
H
Cl


9-5815
4-cyanophenyl
Me
Me
F
F
H
H
Cl
H
heptafluoroisopropyl
H
Cl


9-5830
2-chloropyridin-3-yl
Me
Me
F
F
H
H
Cl
H
heptafluoroisopropyl
H
Cl


9-5872
phenyl
Me
Me
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


9-5892
3-cyanophenyl
Me
Me
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


9-5893
4-cyanophenyl
Me
Me
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


9-5908
2-chloropyridin-3-yl
Me
Me
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


9-5950
phenyl
Me
Me
F
F
H
H
Br
H
heptafluoroisopropyl
H
Br


9-5970
3-cyanophenyl
Me
Me
F
F
H
H
Br
H
heptafluoroisopropyl
H
Br


9-5971
4-cyanophenyl
Me
Me
F
F
H
H
Br
H
heptafluoroisopropyl
H
Br


9-5986
2-chloropyridin-3-yl
Me
Me
F
F
H
H
Br
H
heptafluoroisopropyl
H
Br


9-6028
phenyl
Me
Me
F
F
H
H
Br
H
nonafluoro-2-butyl
H
Br


9-6048
3-cyanophenyl
Me
Me
F
F
H
H
Br
H
nonafluoro-2-butyl
H
Br


9-6049
4-cyanophenyl
Me
Me
F
F
H
H
Br
H
nonafluoro-2-butyl
H
Br


9-6064
2-chloropyridin-3-yl
Me
Me
F
F
H
H
Br
H
nonafluoro-2-butyl
H
Br


9-6106
phenyl
Me
Me
F
F
H
H
I
H
heptafluoroisopropyl
H
I


9-6126
3-cyanophenyl
Me
Me
F
F
H
H
I
H
heptafluoroisopropyl
H
I


9-6127
4-cyanophenyl
Me
Me
F
F
H
H
I
H
heptafluoroisopropyl
H
I


9-6142
2-chloropyridin-3-yl
Me
Me
F
F
H
H
I
H
heptafluoroisopropyl
H
I


9-6184
phenyl
Me
Me
F
F
H
H
I
H
nonafluoro-2-butyl
H
I


9-6204
3-cyanophenyl
Me
Me
F
F
H
H
I
H
nonafluoro-2-butyl
H
I


9-6205
4-cyanophenyl
Me
Me
F
F
H
H
I
H
nonafluoro-2-butyl
H
I


9-6220
2-chloropyridin-3-yl
Me
Me
F
F
H
H
I
H
nonafluoro-2-butyl
H
I


9-6458
phenyl
Me
Me
F
F
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


9-6478
3-cyanophenyl
Me
Me
F
F
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


9-6479
4-cyanephenyl
Me
Me
F
F
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


9-6494
2-chloropyridin-3-yl
Me
Me
F
F
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


9-6536
phenyl
Me
Me
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


9-6556
3-cyanophenyl
Me
Me
F
F
H
H
Cl
Cl
nonafluoro-2-butyl
H
OCF3


9-6557
4-cyanophenyl
Me
Me
F
F
H
F
Cl
H
nonafluoro-2-butyl
H
OCF3


9-6572
2-chloropyridin-3-yl
Me
Me
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


9-6614
phenyl
Me
Me
F
F
H
H
Br
H
heptafluoroisopropyl
H
OCF3


9-6634
3-cyanophenyl
Me
Me
F
F
H
H
Br
H
heptafluoroisopropyl
H
OCF3


9-6635
4-cyanophenyl
Me
Me
F
F
H
H
Br
H
heptafluoroisopropyl
H
OCF3


9-6650
2-chloropyridin-3-yl
Me
Me
F
F
H
H
Br
H
heptafluoroisopropyl
H
OCF3


9-6692
phenyl
Me
Me
F
F
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


9-6712
3-cyanophenyl
Me
Me
F
F
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


9-6713
4-cyanophenyl
Me
Me
F
F
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


9-6728
2-chloropyridin-3-yl
Me
Me
F
F
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


9-6770
phenyl
Me
Me
F
F
H
H
I
H
heptafluoroisopropyl
H
OCF3


9-6790
3-cyanophenyl
Me
Me
F
F
H
H
I
H
heptafluoroisopropyl
H
OCF3


9-6791
4-cyanophenyl
Me
Me
F
F
H
H
I
H
heptafluoroisopropyl
H
OCF3


9-6806
2-chloropyridin-3-yl
Me
Me
F
F
H
H
I
H
heptafluoroisopropyl
H
OCF3


9-6848
phenyl
Me
Me
F
F
H
H
I
H
nonafluoro-2-butyl
H
OCF3


9-6868
3-cyanophenyl
Me
Me
F
F
H
H
I
H
nonafluoro-2-butyl
H
OCF3


9-6869
4-cyanophenyl
Me
Me
F
F
H
H
I
H
nonafluoro-2-butyl
H
OCF3


9-6884
2-chloropyridin-3-yl
Me
Me
F
F
H
H
I
H
nonafluoro-2-butyl
If
OCF3


9-7122
phenyl
Me
Me
F
F
H
H
F
H
heptafluoroisopropyl
H
CF3


9-7123
phenyl
Me
Me
F
F
H
H
Cl
Cl
heptafluoroisopropyl
H
CF3


9-7143
3-cyanophenyl
Me
Me
F
F
H
H
Cl
Cl
heptafluoroisopropyl
H
CF3


9-7144
4-cyanophenyl
Me
Me
F
F
H
H
Cl
H
heptafluoroisopropyl
H
CF3


9-7159
2-chloropyridin-3-yl
Me
Me
F
F
H
H
Cl
H
heptafluoroisopropyl
H
CF3


9-7201
phenyl
Me
Me
F
F
H
H
F
H
nonafluoro-2-butyl
H
CF3


9-7202
phenyl
Me
Me
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


9-7222
3-cyanophenyl
Me
Me
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


9-7223
4-cyanophenyl
Me
Me
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


9-7238
2-chloropyridin-3-yl
Me
Me
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


9-7280
phenyl
Me
Me
F
F
H
H
Br
H
heptafluoroisopropyl
H
CF3


9-7300
3-cyanophenyl
Me
Me
F
F
H
H
Br
H
heptafluoroisopropyl
H
CF3


9-7301
4-cyanophenyl
Me
Me
F
F
H
H
Br
H
heptafluoroisopropyl
H
CF3


9-7316
2-chloropyridin-3-yl
Me
Me
F
F
H
H
Br
H
heptafluoroisopropyl
H
CF3


9-7358
phenyl
Me
Me
F
F
H
H
Br
H
nonafluoro-2-butyl
H
CF3


9-7378
3-cyanophenyl
Me
Me
F
F
H
H
Br
H
nonafluoro-2-butyl
H
CF3


9-7379
4-cyanophenyl
Me
Me
F
F
H
H
Br
H
nonafluoro-2-butyl
H
CF3


9-7394
2-chloropyridin-3-yl
Me
Me
F
F
H
H
Br
H
nonafluoro-2-butyl
H
CF3


9-7436
phenyl
Me
Me
F
F
H
H
I
H
heptafluoroisopropyl
H
CF3


9-7456
3-cyanophenyl
Me
Me
F
F
H
H
I
H
heptafluoroisopropyl
H
CF3


9-7457
4-cyanophenyl
Me
Me
F
F
H
H
I
H
heptafluoroisopropyl
H
CF3


9-7472
2-chloropyridin-3-yl
Me
Me
F
F
H
H
I
H
heptafluoroisopropyl
H
CF3


9-7514
phenyl
Me
Me
F
F
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-7534
3-cyanophenyl
Me
Me
F
F
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-7535
4-cyanophenyl
Me
Me
F
F
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-7550
2-chloropyridin-3-yl
Me
Me
F
F
H
H
I
H
nonafluoro-2-butyl
H
CF3


9-7788
phenyl
Me
Me
F
F
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


9-7819
2-chloropyridin-3-yl
Me
Me
F
F
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


9-7844
phenyl
Me
Me
F
F
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


9-7875
2-chloropyridin-3-yl
Me
Me
F
F
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


9-7900
phenyl
Me
Me
F
F
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


9-7931
2-chloropyridin-3-yl
Me
Me
F
F
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


9-7956
phenyl
Me
Me
F
F
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


9-7987
2-chloropyridin-3-yl
Me
Me
F
F
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


9-8012
phenyl
Me
Me
F
F
H
H
CF3
H
heptafluoroisopropyl
H
CF3


9-8032
3-cyanophenyl
Me
Me
F
F
H
H
CF3
H
heptafluoroisopropyl
H
CF3


9-8033
4-cyanophenyl
Me
Me
F
F
H
H
CF3
H
heptafluoroisopropyl
H
CF3


9-8048
2-chloropyridin-3-yl
Me
Me
F
F
H
H
CF3
H
heptafluoroisopropyl
H
CF3


9-8080
phenyl
Me
Me
F
F
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


9-8100
3-cyanophenyl
Me
Me
F
F
H
F
CF3
H
nonafluoro-2-butyl
H
CF3


9-8101
4-cyanophenyl
Me
Me
F
F
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


9-8116
2-chloropyridin-3-yl
Me
Me
F
F
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


9-8344
phenyl
Me
Me
F
F
F
H
Cl
H
pentafluoroethyl
H
Cl


9-8345
phenyl
Me
Me
F
F
F
H
Br
H
heptafluoroisopropyl
H
Br


9-8346
phenyl
Me
Me
F
F
F
H
Br
H
heptafluoroisopropyl
H
OCF3


9-8347
phenyl
Me
Me
F
F
F
H
I
H
heptafluoroisopropyl
H
CF3


9-8348
phenyl
Me
Me
F
F
F
H
CF3
H
heptafluoroisopropyl
H
CF3


9-8349
phenyl
Me
Me
F
F
F
H
I
H
nonafluoro-2-butyl
H
I


9-8350
phenyl
Me
Me
F
F
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


9-8351
phenyl
Me
Me
F
F
F
H
Br
H
nonafluoro-2-butyl
H
CF3


9-8352
phenyl
Me
Me
F
F
F
H
CF3
H
nonafluoro-2-butyl
H
CF3


9-8353
phenyl
Me
Me
H
H
F
H
Cl
H
pentafluoroethyl
H
Cl


9-8354
phenyl
Me
Me
H
H
F
H
Br
H
heptafluoroisopropyl
H
Br


9-8355
phenyl
Me
Me
H
H
F
H
Br
H
heptafluoroisopropyl
H
OCF3


9-8356
phenyl
Me
Me
H
H
F
H
I
H
heptafluoroisopropyl
H
CF3


9-8357
phenyl
Me
Me
H
H
F
H
CF3
H
heptafluoroisopropyl
H
CF3


9-8358
phenyl
Me
Me
H
H
F
H
I
H
nonafluoro-2-butyl
H
I


9-8359
phenyl
Me
Me
H
H
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


9-8360
phenyl
Me
Me
H
H
F
H
Br
H
nonafluoro-2-butyl
H
CF3


9-8361
phenyl
Me
Me
H
H
F
H
CF3
H
nonafluoro-2-butyl
H
CF3


9-8362
phenyl
Me
Me
H
H
H
F
Cl
H
pentafluoroethyl
H
Cl


9-8363
phenyl
Me
Me
H
H
H
F
Br
H
heptafluoroisopropyl
H
Br


9-8364
phenyl
Me
Me
H
H
H
F
Br
H
heptafluoroisopropyl
H
OCF3


9-8365
phenyl
Me
Me
H
H
H
F
I
H
heptafluoroisopropyl
H
CF3


9-8366
phenyl
Me
Me
H
H
H
F
CF3
H
heptafluoroisopropyl
H
CF3


9-8367
phenyl
Me
Me
H
H
H
F
I
H
nonafluoro-2-butyl
H
I


9-8368
phenyl
Me
Me
H
H
H
F
Cl
H
nonafluoro-2-butyl
H
OCF3


9-8369
phenyl
Me
Me
H
H
H
F
Br
H
nonafluoro-2-butyl
H
CF3


9-8370
phenyl
Me
Me
H
H
H
F
CF3
H
nonafluoro-2-butyl
H
CF3


9-8371
phenyl
Me
Me
F
H
F
H
Cl
H
pentafluoroethyl
H
Cl


9-8372
phenyl
Me
Me
F
H
F
H
Br
H
heptafluoroisopropyl
H
Br


9-8373
phenyl
Me
Me
F
H
F
H
Br
H
heptafluoroisopropyl
H
OCF3


9-8374
phenyl
Me
Me
F
H
F
H
I
H
heptafluoroisopropyl
H
CF3


9-8375
phenyl
Me
Me
F
H
F
H
CF3
H
heptafluoroisopropyl
H
CF3


9-8376
phenyl
Me
Me
F
H
F
H
I
H
nonafluoro-2-butyl
H
I


9-8377
phenyl
Me
Me
F
H
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


9-8378
phenyl
Me
Me
F
H
F
H
Br
H
nonafluoro-2-butyl
H
CF3


9-8379
phenyl
Me
Me
F
H
F
H
CF3
H
nonafluoro-2-butyl
H
CF3


9-8380
phenyl
Me
Me
F
H
H
F
Cl
H
pentafluoroethyl
H
Cl


9-8381
phenyl
Me
Me
F
H
H
F
Br
H
heptafluoroisopropyl
H
Br


9-8382
phenyl
Me
Me
F
H
H
F
Br
H
heptafluoroisopropyl
H
OCF3


9-8383
phenyl
Me
Me
H
F
H
F
I
H
heptafluoroisopropyl
H
CF3


9-8384
phenyl
Me
Me
H
F
H
F
CF3
H
heptafluoroisopropyl
H
CF3


9-8385
phenyl
Me
Me
H
F
H
F
I
H
nonafluoro-2-butyl
H
I


9-8386
phenyl
Me
Me
H
F
H
F
Cl
H
nonafluoro-2-butyl
H
OCF3


9-8387
phenyl
Me
Me
H
F
H
F
Br
H
nonafluoro-2-butyl
H
Cf3


9-8388
phenyl
Me
Me
H
F
H
F
CF3
H
nonafluoro-2-butyl
H
CF3


9-8389
phenyl
Me
Me
H
F
H
F
Cl
H
pentafluoroethyl
H
Cl


9-8390
phenyl
Me
Me
H
F
H
F
Br
H
heptafluoroisopropyl
H
Br


9-8391
phenyl
Me
Me
H
F
H
F
Br
H
heptafluoroisopropyl
H
OCF3


9-8392
phenyl
Me
Me
H
F
H
F
I
H
heptafluoroisopropyl
H
CF3


9-8393
phenyl
Me
Me
H
F
H
F
CF3
H
heptafluoroisopropyl
H
CF3


9-8394
phenyl
Me
Me
H
F
H
F
I
H
nonafluoro-2-butyl
H
I


9-8395
phenyl
Me
Me
H
F
H
F
Cl
H
nonafluoro-2-butyl
H
OCF3


9-8396
phenyl
Me
Me
H
F
H
F
Br
H
nonafluoro-2-butyl
H
CF3


9-8397
phenyl
Me
Me
H
F
H
F
CF3
H
nonafluoro-2-butyl
H
CF3


9-8398
phenyl
Me
Me
H
F
H
F
Cl
H
pentafluoroethyl
H
Cl


9-8399
phenyl
Me
Me
H
F
H
F
Br
H
heptafluoroisopropyl
H
Br


9-8400
phenyl
Me
Me
H
F
H
F
Br
H
heptafluoroisopropyl
H
OCF3


9-8401
phenyl
Me
Me
H
F
H
F
I
H
heptafluoroisopropyl
H
CF3


9-8402
phenyl
Me
Me
H
F
H
F
CF3
H
heptafluoroisopropyl
H
CF3


9-8403
phenyl
Me
Me
H
F
H
F
I
H
nonafluoro-2-butyl
H
I


9-8404
phenyl
Me
Me
H
F
H
F
Cl
H
nonafluoro-2-butyl
H
OCF3


9-8405
phenyl
Me
Me
H
F
H
F
Br
H
nonafluoro-2-butyl
H
CF3


9-8406
phenyl
Me
Me
H
F
H
F
CF3
H
nonafluoro-2-butyl
H
CF3


9-8407
phenyl
Me
Me
H
H
F
F
Cl
H
pentafluoroethyl
H
Cl


9-8408
phenyl
Me
Me
H
H
F
F
Br
H
heptafluoroisopropyl
H
Br


9-8409
phenyl
Me
Me
H
H
F
F
Br
H
heptafluoroisopropyl
H
OCF3


9-8410
phenyl
Me
Me
H
H
F
F
I
H
heptafluoroisopropyl
H
CF3


9-8411
phenyl
Me
Me
H
H
F
F
CF3
H
heptafluoroisopropyl
H
CF3


9-8412
phenyl
Me
Me
H
H
F
F
I
H
nonafluoro-2-butyl
H
I


9-8413
phenyl
Me
Me
H
H
F
F
Cl
H
nonafluoro-2-butyl
H
OCF3


9-8414
phenyl
Me
Me
H
H
F
F
Br
H
nonafluoro-2-butyl
H
CF3


9-8415
phenyl
Me
Me
H
H
F
F
CF3
H
nonafluoro-2-butyl
H
CF3


9-8416
phenyl
Me
Me
F
F
H
F
Cl
H
pentafluoroethyl
H
Cl


9-8417
phenyl
Me
Me
F
F
H
F
Br
H
heptafluoroisopropyl
H
Br


9-8418
phenyl
Me
Me
F
F
H
F
Br
H
heptafluoroisopropyl
H
OCF3


9-8419
phenyl
Me
Me
F
F
H
F
I
H
heptafluoroisopropyl
H
CF3


9-8420
phenyl
Me
Me
F
F
H
F
CF3
H
heptafluoroisopropyl
H
CF3


9-8421
phenyl
Me
Me
F
F
H
F
I
H
nonafluoro-2-butyl
H
I


9-8422
phenyl
Me
Me
F
F
H
F
Cl
H
nonafluoro-2-butyl
H
OCF3


9-8423
phenyl
Me
Me
F
F
H
F
Br
H
nonafluoro-2-butyl
H
CF3


9-8424
phenyl
Me
Me
F
F
H
F
CF3
H
nonafluoro-2-butyl
H
CF3


9-8425
phenyl
Me
Me
F
H
F
F
Cl
H
pentafluoroethyl
H
Cl


9-8426
phenyl
Me
Me
F
H
F
F
Br
H
heptafluoroisopropyl
H
Br


9-8427
phenyl
Me
Me
F
H
F
F
Br
H
heptafluoroisopropyl
H
OCF3


9-8428
phenyl
Me
Me
F
H
F
F
I
H
heptafluoroisopropyl
H
CF3


9-8429
phenyl
Me
Me
F
H
F
F
CF3
H
heptafluoroisopropyl
H
CF3


9-8430
phenyl
Me
Me
F
H
F
F
I
H
nonafluoro-2-butyl
H
I


9-8431
phenyl
Me
Me
F
H
F
F
Cl
H
nonafluoro-2-butyl
H
OCF3


9-8432
phenyl
Me
Me
F
H
F
F
Br
H
nonafluoro-2-butyl
H
CF3


9-8433
phenyl
Me
Me
F
H
F
F
CF3
H
nonafluoro-2-butyl
H
CF3


9-8434
phenyl
Me
Me
H
F
F
F
Cl
H
pentafluoroethyl
H
Cl


9-8435
phenyl
Me
Me
H
F
F
F
Br
H
heptafluoroisopropyl
H
Br


9-8436
phenyl
Me
Me
H
F
F
F
Br
H
heptafluoroisopropyl
H
OCF3


9-8437
phenyl
Me
Me
H
F
F
F
I
H
heptafluoroisopropyl
H
CF3


9-8438
phenyl
Me
Me
H
F
F
F
CF3
H
heptafluoroisopropyl
H
CF3


9-8439
phenyl
Me
Me
H
F
F
F
I
H
nonafluoro-2-butyl
H
I


9-8440
phenyl
Me
Me
H
F
F
F
Cl
H
nonafluoro-2-butyl
H
OCF3


9-8441
phenyl
Me
Me
H
F
F
F
Br
H
nonafluoro-2-butyl
H
CF3


9-8442
phenyl
Me
Me
H
F
F
F
CF3
H
nonafluoro-2-butyl
H
CF3


9-8443
phenyl
Me
Me
F
F
F
F
Cl
H
pentafluoroethyl
H
Cl


9-8444
phenyl
Me
Me
F
F
F
F
Br
H
heptafluoroisopropyl
H
Br


9-8445
phenyl
Me
Me
F
F
F
F
Br
H
heptafluoroisopropyl
H
OCF3


9-8446
phenyl
Me
Me
F
F
F
F
I
H
heptafluoroisopropyl
H
CF3


9-8447
phenyl
Me
Me
F
F
F
F
CF3
H
heptafluoroisopropyl
H
CF3


9-8448
phenyl
Me
Me
F
F
F
F
I
H
nonafluoro-2-butyl
H
I


9-8449
phenyl
Me
Me
F
F
F
F
Cl
H
nonafluoro-2-butyl
H
OCF3


9-8450
phenyl
Me
Me
F
F
F
F
Br
H
nonafluoro-2-butyl
H
CF3


9-8451
phenyl
Me
Me
F
F
F
F
CF3
H
nonafluoro-2-butyl
H
CF3











embedded image





















TABLE 10





compound














number
Q1
R1
R2
X1
X2
X3
X4
Y1
Y2
Y3
Y4
Y5







10-9
3-bromophenyl
H
Et
H
H
H
H
Cl
F
nonafluoro-2-butyl
F
Cl


10-39
2-iodopyridin-3-yl
H
H
H
H
H
H
Cl
Me
nonafluoro-2-butyl
Me
I


10-148
2-chlorophenyl
H
H
H
H
H
H
F
Br
heptafluoroisopropyl
H
CF3


10-153
4-bromophenyl
H
H
H
H
H
H
Cl
F
heptafluoroisopropyl
Cl
CF3


10-167
3,4-dichlorophenyl
H
H
H
H
H
H
Cl
I
nonafluoro-2-butyl
I
CF3


10-168
2,4-dichlorophenyl
H
H
H
H
H
H
Cl
Me
nonafluoro-2-butyl
H
CF3


10-169
2-chloro-4-fluorophenyl
H
H
H
H
H
H
Cl
H
nonafluoro-2-butyl
Me
CF3


10-170
2-chloro-4,5-difluorophenyl
i-Pr
H
H
H
H
H
Cl
Et
nonafluoro-2-butyl
H
CF3


10-171
4-bromo-2-chlorophenyl
H
H
H
H
H
H
Cl
H
nonafluoro-2-butyl
Et
CF3


10-182
2-iodopyridin-3-yl
H
H
H
H
H
H
Cl
Me
nonafluoro-2-butyl
Me
n-C3F7


10-183
2-(trifluoromethyl) pyridin-3-yl
H
H
H
H
H
H
Cl
Me
nonafluoro-2-butyl
Et
i-C3F7


10-189
6-iodopyridin-3-yl
H
H
H
H
H
H
Cl
Et
nonafluoro-2-butyl
Me
n-C3F7


10-190
6-(trifluoromethyl) pyridin-3-yl
H
H
H
H
H
H
Cl
Et
nonafluoro-2-butyl
Et
i-C3F7


10-196
5-bromopyridin-3-yl
H
H
H
H
H
H
Br
n-Pr
heptafluoroisopropyl
Me
CF3


10-197
5-iodopyridin-3-yl
H
H
H
H
H
H
Br
n-Pr
heptafluoroisopropyl
Et
CF3


10-203
4-bromopyridin-3-yl
Me
n-Pr
H
H
H
H
Br
i-Pr
heptafluoroisopropyl
Me
CF3


10-204
4-iodopyridin-3-yl
H
H
H
H
H
H
Br
i-Pr
heptafluoroisopropyl
Et
CF3


10-210
pyridin-4-yl
H
H
H
Fl
H
H
Br
n-Bu
heptafluoroisopropyl
Me
CF3


10-211
2-chloropyridin-4-yl
H
H
H
H
H
H
Br
n-Bu
heptafluoroisopropyl
Et
CF3


10-217
pyridin-2-yl
H
H
H
H
H
H
Br
i-Bu
nonafluoro-2-butyl
Me
CF3


10-218
3-chloropyridin-2-yl
H
H
H
H
H
H
Br
i-Bu
nonafluoro-2-butyl
Et
CF3


10-224
2-fluorophenyl
H
H
H
H
H
H
Br
s-Bu
nonafluoro-2-butyl
Me
CF3


10-225
3-fluorophenyl
H
H
H
H
H
H
Br
s-Bu
nonafluoro-2-butyl
Et
CF3


10-231
3-bromophenyl
H
H
H
H
H
H
Br
F
nonafluoro-2-butyl
Me
CF3


10-232
4-bromophenyl
H
H
H
H
H
H
Br
F
nonafluoro-2-butyl
Et
CF3


10-238
(4-trifluoromethyl) phenyl
Et
i-Pr
H
H
H
H
Br
Cl
nonafluoro-2-butyl
Me
CF3


10-239
2-nitrophenyl
H
H
H
H
H
H
Br
Cl
nonafluoro-2-butyl
Et
CF3


10-245
4-cyanophenyl
H
H
H
H
H
H
I
Br
heptafluoroisopropyl
Me
CF3


10-246
2,6-difluorophenyl
H
H
H
H
H
H
I
Br
heptafluoroisopropyl
Et
CF3


10-252
2-bromo-4-chlorophenyl
n-Pr
Me
H
H
H
H
I
I
heptafluoroisopropyl
Me
CF3


10-253
2-bromo-4-fluorophenyl
H
H
H
H
H
H
I
I
heptafluoroisopropyl
Et
CF3


10-259
2-fluoropyridin-3-yl
H
H
H
H
H
H
I
Me
heptafluoroisopropyl
F
C2F5


10-260
2-chloropyridin-3-yl
H
H
H
H
H
H
I
Me
nonafluoro-2-butyl
Cl
CF3


10-263
2-(triluoromethyl) pyridin-3-yl
H
H
H
H
H
H
I
Et
nonafluoro-2-butyl
F
CF3


10-264
2-nitropyridin-3-yl
H
H
H
H
H
H
I
Et
nonafluoro-2-butyl
Cl
CF3


10-267
6-chloropyridin-3-yl
H
H
H
H
H
H
I
n-Pr
nonafluoro-2-butyl
F
CF3


10-268
6-bromopyridin-3-yl
H
H
H
H
H
H
I
n-Pr
nonafluoro-2-butyl
Cl
CF3


10-271
6-nitropyridin-3-yl
H
H
H
H
H
H
I
i-Pr
nonafluoro-2-butyl
F
i-C3F7


10-272
6-cyanopyridin-3-yl
H
H
H
H
H
H
I
i-Pr
nonafluoro-2-butyl
Cl
CF3


10-275
5-bromopyridin-3-yl
H
H
H
H
H
H
I
n-Bu
nonafluoro-2-butyl
F
CF3


10-276
5-iodopyridin-3-yl
H
H
H
H
H
H
I
n-Bu
nonafluoro-2-butyl
Cl
CF3


10-279
5-cyanopyr4in-3-yl
H
H
H
H
H
H
I
i-Bu
nonafluoro-2-butyl
F
CF3


10-280
4-fluoropyridin-3-yl
H
H
H
H
H
H
I
i-Bu
nonafluoro-2-butyl
Cl
CF3


10-283
4-iodopyridin-3-yl
i-Pr
n-Pr
H
H
H
H
I
s-Bu
nonafluoro-2-butyl
F
CF3


10-284
4-(trifluoromethyl) pyridin-3-yl
H
H
H
H
H
H
I
s-Bu
nonafluoro-2-butyl
Cl
CF3


10-295
3-bromophenyl
H
Et
H
H
H
H
OCF3
F
heptafluoroisopropyl
F
OCF3


10-325
2-iodopyridin-3-yl
H
H
H
H
H
H
OCF3
Me
nonafluoro-2-butyl
Me
OCF3


10-438
3-bromophenyl
H
Et
H
H
H
H
OCF3
F
heptafluoroisopropyl
F
CF3


10-468
2-iodopyridin-3-yl
H
H
H
H
H
H
OCF3
Me
nonafluoro-2-butyl
Me
CF3


10-581
3-bromophenyl
H
Et
H
H
H
H
CF3
F
heptafluoroisopropyl
F
CF3


10-611
2-iodopyridin-3-yl
H
H
H
H
H
H
CF3
Me
nonafluoro-2-butyl
Me
CF3


10-724
3-bromophenyl
H
Et
F
H
H
H
Cl
F
heptafluoroisopropyl
F
Cl


10-754
2-iodopyridin-3-yl
H
H
F
H
H
H
Cl
Me
nonafluoro-2-butyl
Me
I


10-859
phenyl
H
H
F
H
H
H
Cl
F
heptafluoroisopropyl
H
CF3


10-860
2-fluorophenyl
Me
H
F
H
H
H
Cl
H
heptafluoroisopropyl
F
CF3


10-861
3-fluorophenyl
H
Me
F
H
H
H
Cl
Cl
heptafluoroisopropyl
H
CF3


10-862
4-fluorophenyl
Me
Me
F
H
H
H
Cl
H
heptafluoroisopropyl
Cl
CF3


10-863
2-chlorophenyl
H
H
F
H
H
H
F
Br
heptafluoroisopropyl
H
CF3


10-864
3-chlorophenyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
Br
CF3


10-865
4-chlorophenyl
Et
H
F
H
H
H
Cl
I
heptafluoroisopropyl
H
C2F5


10-866
2-bromophenyl
H
H
F
H
H
H
Cl
H
heptafluorolsopropyl
I
CF3


10-867
3-bromophenyl
H
Et
F
H
H
H
Cl
F
heptafluoroisopropyl
F
CF3


10-868
4-bromophenyl
H
H
F
H
H
H
Cl
F
heptafluoroisopropyl
Cl
CF3


10-869
2-iodophenyl
H
H
F
H
H
H
Cl
F
heptafluoroisopropyl
Br
CF3


10-870
3-iodophenyl
Et
Et
F
H
H
H
Cl
F
pentafluoroethyl
I
C2F5


10-871
4-iodophenyl
H
H
F
H
H
H
Cl
Cl
pentafluoroethyl
F
CF3


10-872
(2-trifluoromethyl) phenyl
H
H
F
H
H
H
Cl
Cl
heptafluoroisopropyl
Cl
CF3


10-873
(3-trifluoromethyl) phenyl
n-Pr
H
F
H
H
H
Cl
Cl
heptafluoroisopropyl
Br
CF3


10-874
(4-trifluoromethyl) phenyl
H
H
F
H
H
H
Cl
Cl
heptafluoroisopropyl
I
n-C3F7


10-875
2-nitrophenyl
H
n-Pr
F
H
H
H
Cl
Br
heptafluoroisopropyl
F
CF3


10-876
3-nitrophenyl
H
H
F
H
H
H
Cl
Br
heptafluoroisopropyl
Cl
CF3


10-877
4-nitrophenyl
H
H
F
H
H
H
Cl
Br
heptafluoroisopropyl
Br
CF3


10-878
2-cyanophenyl
n-Pr
n-Pr
F
H
H
H
Cl
Br
pentafluoroethyl
I
CF3


10-879
3-cyanophenyl
H
H
F
H
H
H
F
I
nonafluoro-2-butyl
F
CF3


10-880
4-cyanophenyl
H
H
F
H
H
H
Cl
I
nonafluoro-2-butyl
Cl
CF3


10-881
2,6-difluorophenyl
H
H
F
H
H
H
Cl
I
nonafluoro-2-butyl
Br
CF3


10-882
3,4-dichlorophenyl
H
H
F
H
H
H
Cl
I
nonafluoro-2-butyl
I
CF3


10-883
2,4-dichlorophenyl
H
H
F
H
H
H
Cl
Me
nonafluoro-2-butyl
H
CF3


10-884
2-chloro-4-fluorophenyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
Me
CF3


10-885
2-chloro-4,5-difluorophenyl
i-Pr
H
F
H
H
H
Cl
Et
nonafluoro-2-butyl
H
CF3


10-886
4-bromo-2-chlorophenyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
Et
CF3


10-887
2-bromo-4-chlorophenyl
H
H
F
H
H
H
Cl
n-Pr
nonafluoro-2-butyl
H
CF3


10-888
2-bromo-4-fluorophenyl
H
i-Pr
F
H
H
H
Cl
H
nonafluoro-2-butyl
n-Pr
CF3


10-889
2-chloro-4-nitrophenyl
i-Pr
i-Pr
F
H
H
H
Cl
i-Pr
nonafluoro-2-butyl
H
CF3


10-890
3,5-dicyanophenyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
i-Pr
CF3


10-891
4-cyano-2-fluorophenyl
H
H
F
H
H
H
Cl
n-Bu
nonafluoro-2-butyl
H
CF3


10-892
2-chloro-4-cyanophenyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
n-Bu
CF3


10-893
pyridin-3-yl
H
H
F
H
H
H
Cl
i-Bu
nonafluoro-2-butyl
H
CF3


10-894
2-fluoropyridin-3-yl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
i-Bu
CF3


10-895
2-chloropyridin-3-yl
H
H
F
H
H
H
Cl
s-Bu
nonafluoro-2-butyl
H
C2F5


10-896
2-bromopyridin-3-yl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
s-Bu
CF3


10-897
2-iodopyridin-3-yl
H
H
F
H
H
H
Cl
Me
nonafluoro-2-butyl
Me
n-C3F7


10-898
2-(trifluoromethyl) pyridin-3-yl
H
H
F
H
H
H
Cl
Me
nonafluoro-2-butyl
Et
i-C3F7


10-899
2-nitropyridin-3-yl
C(O)Me
H
F
H
H
H
Cl
Me
nonafluoro-2-butyl
n-Pr
CF3


10-900
2-cyanopyridin-3-yl
H
H
F
H
H
H
Cl
Me
nonafluoro-2-butyl
i-Pr
CF3


10-901
6-fluoropyridin-3-yl
H
H
F
H
H
H
Cl
Me
nonafluoro-2-butyl
n-Bu
CF3


10-902
6-chloropyridin-3-yl
H
H
F
H
H
H
Cl
Me
nonafluoro-2-butyl
i-Bu
CF3


10-903
6-bromopyridin-3-yl
H
C(O)Me
F
H
H
H
Cl
Me
nonafluoro-2-butyl
s-Bu
CF3


10-904
6-iodopyridin-3-yl
H
H
F
H
H
H
Cl
Et
nonafluoro-2-butyl
Me
n-C3F7


10-905
6-(trifluoromethyl) pyridin-3-yl
H
H
F
H
H
H
Cl
Et
nonafluoro-2-butyl
Et
i-C3F7


10-906
6-nitropyridin-3-yl
C(O)Me
C(O)Me
F
H
H
H
Cl
Et
nonafluoro-2-butyl
n-Pr
CF3


10-907
6-cyanopyridin-3-yl
H
H
F
H
H
H
Cl
Et
nonafluoro-2-butyl
i-Pr
CF3


10-908
phenyl
H
H
F
H
H
H
Br
Et
nonafluoro-2-butyl
n-Bu
CF3


10-909
5-fluoropyridin-3-yl
H
H
F
H
H
H
Br
Et
heptafluoroisopropyl
i-Bu
CF3


10-910
5-chloropyridin-3yl
H
H
F
H
H
H
Br
Et
heptafluoroisopropyl
s-Bu
CF3


10-911
5-bromopyridin-3-yl
H
H
F
H
H
H
Br
n-Pr
heptafluoroisopropyl
Me
CF3


10-912
5-iodopyridin-3-yl
H
H
F
H
H
H
Br
n-Pr
heptafluoroisopropyl
Et
CF3


10-913
5-(trifluoromethyl) pyridin-3-yl
Me
Et
F
H
H
H
Br
n-Pr
pentafluoroethyl
n-Pr
CF3


10-914
5-nitropyridin-3-yl
H
H
F
H
H
H
Br
n-Pr
heptafluoroisopropyl
i-Pr
CF3


10-915
5-cyanopyridin-3-yl
H
H
F
H
H
H
Br
n-Pr
pentafluoroethyl
n-Bu
CF3


10-916
4-fluoropyridin-3-yl
H
H
F
H
H
H
Br
n-Pr
heptafluoroisopropyl
i-Bu
CF3


10-917
4-chloropyridin-3-yl
H
H
F
H
H
H
Br
n-Pr
heptafluoroisopropyl
s-Bu
CF3


10-918
4-bromopyridin-3-yl
Me
n-Pr
F
H
H
H
Br
i-Pr
heptafluoroisopropyl
Me
CF3


10-919
4-iodopyridin-3-yl
H
H
F
H
H
H
Br
i-Pr
heptafluoroisopropyl
Et
CF3


10-920
4-(trifluoromethyl) pyridin-3-yl
H
H
F
H
H
H
Br
i-Pr
heptafluoroisopropyl
n-Pr
CF3


10-921
4-nitropyridin-3-yl
H
H
F
H
H
H
Br
i-Pr
heptafluoroisopropyl
i-Pr
CF3


10-922
4-cyanopyridin-3-yl
H
H
F
H
H
H
Br
i-Pr
heptafluoroisopropyl
n-Bu
CF3


10-923
2,6-dichloropyridin-3-yl
H
H
F
H
H
H
Br
i-Pr
heptafluoroisopropyl
i-Bu
CF3


10-924
pyridin-3-yl N-oxide
Me
i-Pr
F
H
H
H
Br
i-Pr
heptafluoroisopropyl
s-Bu
CF3


10-925
pyridin-4-yl
H
H
F
H
H
H
Br
n-Bu
heptafluoroisopropyl
Me
CF3


10-926
2-chloropyridin-4-yl
H
H
F
H
H
H
Br
n-Bu
heptafluoroisopropyl
Et
CF3


10-927
3-bromopyridin-4-yl
H
H
F
H
H
H
Br
n-Bu
heptafluoroisopropyl
n-Pr
CF3


10-928
3,5-dichloropyridin-4-yl
H
H
F
H
H
H
Br
n-Bu
nonafluoro-2-butyl
i-Pr
CF3


10-929
3-(trifluoromethyl) pyridin-4-yl
H
H
F
H
H
H
Br
n-Bu
nonafluoro-2-butyl
n-Bu
CF3


10-930
2,5-dicyanopyridin-4-yl
H
H
F
H
H
H
Br
n-Bu
nonafluoro-2-butyl
i-Bu
CF3


10-931
pyridin-4-yl N-oxide
Me
C(O)Me
F
H
H
H
Br
n-Bu
nonafluoro-2-butyl
s-Bu
CF3


10-932
pyridin-2-yl
H
H
F
H
H
H
Br
i-Bu
nonafluoro-2-butyl
Me
CF3


10-933
3-chloropyridin-2-yl
H
H
F
H
H
H
Br
i-Bu
nonafluoro-2-butyl
Et
CF3


10-934
4-bromopyridin-2-yl
H
H
F
H
H
H
Br
i-Bu
nonafluoro-2-butyl
n-Pr
CF3


10-935
5-iodopyridin-2-yl
H
H
F
H
H
H
Br
i-Bu
nonafluoro-2-butyl
i-Pr
CF3


10-936
6-chloropyridin-2-yl
H
H
F
H
H
H
Br
i-Bu
nonafluoro-2-butyl
n-Bu
CF3


10-937
4-cyanopyridin-2-yl
H
H
F
H
H
H
Br
i-Bu
nonafluoro-2-butyl
i-Bu
CF3


10-938
phenyl
H
H
F
H
H
H
Br
i-Bu
nonafluoro-2-butyl
s-Bu
C2F5


10-939
2-fluorophenyl
H
H
F
H
H
H
Br
s-Bu
nonafluoro-2-butyl
Me
CF3


10-940
3-fluorophenyl
H
H
F
H
H
H
Br
s-Bu
nonafluoro-2-butyl
Et
CF3


10-941
4-fluorophenyl
H
H
F
H
H
H
Br
s-Bu
nonafluoro-2-butyl
n-Pr
CF3


10-942
2-chlorophenyl
H
H
F
H
H
H
Br
s-Bu
nonafluoro-2-butyl
i-Pr
CF3


10-943
3-chlorophenyl
H
H
F
H
H
H
Br
s-Bu
nonafluoro-2-butyl
n-Bu
CF3


10-944
4-chlorophenyl
H
H
F
H
H
H
Br
s-Bu
nonafluoro-2-butyl
i-Bu
CF3


10-945
2-bromophenyl
Et
Me
F
H
H
H
Br
s-Bu
nonafluoro-2-butyl
s-Bu
CF3


10-946
3-bromophenyl
H
H
F
H
H
H
Br
F
nonafluoro-2-butyl
Me
CF3


10-947
4-bromophenyl
H
H
F
H
H
H
Br
F
nonafluoro-2-butyl
Et
CF3


10-948
2-iodophenyl
H
H
F
H
H
H
Br
F
nonafluoro-2-butyl
n-Pr
CF3


10-949
3-iodophenyl
H
H
F
H
H
H
Br
F
nonafluoro-2-butyl
i-Pr
CF3


10-950
4-iodophenyl
H
H
F
H
H
H
Br
F
nonafluoro-2-butyl
n-Bu
CF3


10-951
(2-trifluoromethyl) phenyl
H
H
F
H
H
H
Br
F
nonafluoro-2-butyl
i-Bu
CF3


10-952
(3-trifluoromethyl) phenyl
Et
n-Pr
F
H
H
H
Br
F
nonafluoro-2-butyl
s-Bu
CF3


10-953
(4-trifluoromethyl) phenyl
Et
i-Pr
F
H
H
H
Br
Cl
nonafluoro-2-butyl
Me
CF3


10-954
2-nitrophenyl
H
H
F
H
H
H
Br
Cl
nonafluoro-2-butyl
Et
CF3


10-955
phenyl
H
H
F
H
H
H
I
Cl
pentafluoroethyl
n-Pr
i-C3F7


10-956
3-ntrophenyl
H
H
F
H
H
H
I
Cl
heptafluoroisopropyl
i-Pr
CF3


10-957
4-nitrophenyl
H
H
F
H
H
H
I
Cl
heptafluoroisopropyl
n-Bu
CF3


10-958
2-cyanophenyl
Et
C(O)Me
F
H
H
H
I
Cl
heptafluoroisopropyl
i-Bu
CF3


10-959
3-cyanophenyl
H
H
F
H
H
H
I
Cl
heptafluoroisopropyl
s-Bu
CF3


10-960
4-cyanophenyl
H
H
F
H
H
H
I
Br
heptafluoroisopropyl
Me
CF3


10-961
2,6-difluorophenyl
H
H
F
H
H
H
I
Br
heptafluoroisopropyl
Et
CF3


10-962
3,4-dichlorophenyl
H
H
F
H
H
H
I
Br
pentafluoroethyl
n-Pr
CF3


10-963
2,4-dichlorophenyl
H
H
F
H
H
H
I
Br
heptafluoroisopropyl
i-Pr
CF3


10-964
2-chloro-4-fluorophenyl
H
H
F
H
H
H
I
Br
heptafluoroisopropyl
n-Bu
CF3


10-955
2-chloro-4,5-difluorophenyl
H
H
F
H
H
H
I
Br
heptafluoroisopropyl
i-Bu
CF3


10-966
4-bromo-2-chlorophenyl
H
H
F
H
H
H
I
Br
heptafluoroisopropyl
s-Bu
CF3


10-967
2-bromo-4-chlorophenyl
n-Pr
Me
F
H
H
H
I
I
heptafluoroisopropyl
Me
CF3


10-968
2-bromo-4-fluorophenyl
H
H
F
H
H
H
I
I
heptafluoroisopropyl
Et
CF3


10-969
2-chloro-4-nitrophenyl
n-Pr
Et
F
H
H
H
I
I
heptafluoroisopropyl
n-Pr
CF3


10-970
3,5-dicyanophenyl
H
H
F
H
H
H
I
I
heptafluoroisopropyl
i-Pr
CF3


10-971
4-cyano-2-fluorophenyl
H
H
F
H
H
H
I
I
heptafluoroisopropyl
n-Bu
CF3


10-972
2-chloro-4-cyanophenyl
H
H
F
H
H
H
I
I
heptafluoroisopropyl
i-Bu
CF3


10-973
pyridin-3-yl
H
H
F
H
H
H
I
I
heptafluoroisopropyl
s-Bu
CF3


10-974
2-fluoropyridin-3-yl
H
H
F
H
H
H
I
Me
heptafluoroisopropyl
F
C2F5


10-975
2-chloropyridin-3-yl
H
H
F
H
H
H
I
Me
nonafluoro-2-butyl
Cl
CF3


10-976
2-bromopyridin-3-yl
H
H
F
H
H
H
I
Me
nonafluoro-2-butyl
Br
n-C3F7


10-977
2-iodopyridin-3-yl
H
H
F
H
H
H
I
Me
nonafluoro-2-butyl
I
i-C3F7


10-978
2-(trifluoromethyl) pyridin-3-yl
H
H
F
H
H
H
I
Et
nonafluoro-2-butyl
F
CF3


10-979
2-nitropyridin-3-yl
H
H
F
H
H
H
I
Et
nonafluoro-2-butyl
Cl
CF3


10-980
2-cyanopyridin-3-yl
H
H
F
H
H
H
I
Et
nonafluoro-2-butyl
Br
CF3


10-981
6-fluoropyridin-3-yl
n-Pr
i-Pr
F
H
H
H
I
Et
nonafluoro-2-butyl
I
C2F5


10-982
6-chloropyridin-3-yl
H
H
F
H
H
H
I
n-Pr
nonafluoro-2-butyl
F
CF3


10-983
6-bromopyridin-3-yl
H
H
F
H
H
H
I
n-Pr
nonafluoro-2-butyl
Cl
CF3


10-984
6-iodopyridin-3-yl
H
H
F
H
H
H
I
n-Pr
nonafluoro-2-butyl
Br
CF3


10-985
6-(trifluoromethyl) pyridin-3-yl
H
H
F
H
H
H
I
n-Pr
nonafluoro-2-butyl
I
n-C3F7


10-986
6-nitropyridin-3-yl
H
H
F
H
H
H
I
i-Pr
nonafluoro-2-butyl
F
i-C3F7


10-987
6-cyanopyridin-3-yl
H
H
F
H
H
H
I
i-Pr
nonafluoro-2-butyl
Cl
CF3


10-988
5-fluoropyridin-3-yl
n-Pr
C(O)Me
F
H
H
H
I
i-Pr
nonafluoro-2-butyl
Br
CF3


10-989
5-chloropyridin-3-yl
H
H
F
H
H
H
I
i-Pr
nonafluoro-2-butyl
I
CF3


10-990
5-bromopyridin-3-yl
H
H
F
H
H
H
I
n-Bu
nonafluoro-2-butyl
F
CF3


10-991
5-iodopyridin-3-yl
H
H
F
H
H
H
I
n-Bu
nonafluoro-2-butyl
Cl
CF3


10-992
5-(trifluoromethyl) pyridin-3-yl
H
H
F
H
H
H
I
n-Bu
nonafluoro-2-butyl
Br
CF3


10-993
5-nitropyridin-3-yl
i-Pr
Me
F
H
H
H
I
n-Bu
nonafluoro-2-butyl
I
CF3


10-994
5-cyanopyridin-3-yl
H
H
F
H
H
H
I
i-Bu
nonafluoro-2-butyl
F
CF3


10-995
4-fluoropyrdin-3-yl
H
H
F
H
H
H
I
i-Bu
nonafluoro-2-butyl
Cl
CF3


10-996
4-chloropyridin-3-yl
H
H
F
H
H
H
I
i-Bu
nonafluoro-2-butyl
Br
CF3


10-997
4-bromopyridin-3-yl
i-Pr
Et
F
H
H
H
I
i-Bu
nonafluoro-2-butyl
I
CF3


10-998
4-iodopyridin-3-yl
i-Pr
n-Pr
F
H
H
H
I
s-Bu
nonafluoro-2-butyl
F
CF3


10-999
4-(trifluoromethyl) pyridin-3-yl
H
H
F
H
H
H
I
s-Bu
nonafluoro-2-butyl
Cl
CF3


10-1000
4-nitropyridin-3-yl
i-Pr
C(O)Me
F
H
H
H
I
s-Bu
nonafluoro-2-butyl
Br
CF3


10-1001
4-cyanopyridin-3-yl
H
H
F
H
H
H
I
s-Bu
nonafluoro-2-butyl
I
CF3


10-1010
3-bromophenyl
H
Et
F
H
H
H
OCF3
F
heptafluoroisopropyl
F
OCF3


10-1040
2-iodopyridin-3-yl
H
H
F
H
H
H
OCF3
Me
nonafluoro-2-butyl
Me
OCF3


10-1153
3-bromophenyl
H
Et
F
H
H
H
OCF3
F
heptafluoroisopropyl
F
CF3


10-1183
2-iodopyridin-3-yl
H
H
F
H
H
H
OCF3
Me
nonafluoro-2-butyl
Me
CF3


10-1296
3-bromophenyl
H
Et
F
H
H
H
CF3
F
heptafluoroisopropyl
F
CF3


10-1326
2-iodopyridin-3-yl
H
H
F
H
H
H
CF3
Me
nonafluoro-2-butyl
Me
CF3


10-1439
3-bromophenyl
H
Et
H
F
H
H
Cl
F
heptafluoroisopropyl
F
Cl


10-1469
2-iodopyridin-3-yl
H
H
H
F
H
H
Cl
Me
nonafluoro-2-butyl
Me
I


10-1582
3-bromophenyl
H
Et
H
F
H
H
Cl
F
heptafluoroisopropyl
F
OCF3


10-1612
2-iodopyridin-3-yl
H
H
H
F
H
H
Cl
Me
nonafluoro-2-butyl
Me
OCF3


10-1726
4-bromophenyl
H
H
H
F
H
H
Cl
F
heptafluaroisopropyl
Cl
CF3


10-1733
2-nitrophenyl
H
n-Pr
H
F
H
H
Cl
Br
heptafluoroisopropyl
F
CF3


10-1741
2,4-dichlorophenyl
H
H
H
F
H
H
Cl
Me
nonafluoro-2-butyl
H
CF3


10-1742
2-chloro-4-fluorophenyl
H
H
H
F
H
H
Cl
H
nonafluoro-2-butyl
Me
CF3


10-1743
2-chloro-4,5-difluorophenyl
i-Pr
H
H
F
H
H
Cl
Et
nonafluoro-2-butyl
H
CF3


10-1744
4-bromo-2-chlorophenyl
H
H
H
F
H
H
Cl
H
nonafluoro-2-butyl
Et
CF3


10-1755
2-iodopyridin-3-yl
H
H
H
F
H
H
Cl
Me
nonafluoro-2-butyl
Me
n-C3F7


10-1756
2-(trifluoromethyl) pyridin-3-yl
H
H
H
F
H
H
Cl
Me
nonafluoro-2-butyl
Et
i-C3F7


10-1762
6-iodopyridin-3-yl
H
H
H
F
H
H
Cl
Et
nonafluoro-2-butyl
Me
n-C3F7


10-1763
6-(trifluoromethyl) pyridin-3-yl
H
H
H
F
H
H
Cl
Et
nonafluoro-2-butyl
Et
i-C3F7


10-1769
5-bromopyridin-3-yl
H
H
H
F
H
H
Br
n-Pr
heptafluoroisopropyl
Me
CF3


10-1770
5-iodopyridin-3-yl
H
H
H
F
H
H
Br
n-Pr
heptafluoroisopropyl
Et
CF3


10-1776
4-bromopyridin-3-yl
Me
n-Pr
H
F
H
H
Br
i-Pr
heptafluoroisopropyl
Me
CF3


10-1777
4-iodopyridin-3-yl
H
H
H
F
H
H
Br
i-Pr
heptafluoroisopropyl
Et
CF3


10-1783
pyridin-4-yl
H
H
H
F
H
H
Br
n-Bu
heptafluoroisopropyl
Me
CF3


10-1784
2-chloropyridin-4-yl
H
H
H
F
H
H
Br
n-Bu
heptafluoroisopropyl
Et
CF3


10-1790
pyridin-2-yl
H
H
H
F
H
H
Br
i-Bu
nonafluoro-2-butyl
Me
CF3


10-1791
3-chloropyridin-2-yl
H
H
H
F
H
H
Br
i-Bu
nonafluoro-2-butyl
Et
CF3


10-1797
2-fluorophenyl
H
H
H
F
H
H
Br
s-Bu
nonafluoro-2-butyl
Me
CF3


10-1798
3-fluorophenyl
H
H
H
F
H
H
Br
s-Bu
nonafluoro-2-butyl
Et
CF3


10-1804
3-bromophenyl
H
H
H
F
H
H
Br
F
nonafluoro-2-butyl
Me
CF3


10-1805
4-bromophenyl
H
H
H
F
H
H
Br
F
nonafluoro-2-butyl
Et
CF3


10-1811
(4-trifluoromethyl) phenyl
Et
i-Pr
H
F
H
H
Br
Cl
nonafluoro-2-butyl
Me
CF3


10-1812
2-nitrophenyl
H
H
H
F
H
H
Br
Cl
nonafluoro-2-butyl
Et
CF3


10-1818
4-cyanophenyl
H
H
H
F
H
H
I
Br
heptafluoroisopropyl
Me
CF3


10-1819
2,6-difluorophenyl
H
H
H
F
H
H
I
Br
heptafluoroisopropyl
Et
CF3


10-1825
2-bromo-4-chlorophenyl
n-Pr
Me
H
F
H
H
I
I
heptafluoroisopropyl
Me
CF3


10-1826
2-bromo-4-fluorophenyl
H
H
H
F
H
H
I
I
heptafluoroisopropyl
Et
CF3


10-1832
2-fluoropyridin-3-yl
H
H
H
F
H
H
I
Me
heptafluoroisopropyl
F
C2F5


10-1833
2-chloropyridin-3-yl
H
H
H
F
H
H
I
Me
nonafluoro-2-butyl
Cl
CF3


10-1834
2-bromopyridin-3-yl
H
H
H
F
H
H
I
Me
nonafluoro-2-butyl
Br
n-C3F7


10-1837
2-nitropyridin-3-yl
H
H
H
F
H
H
I
Et
nonafluoro-2-butyl
Cl
CF3


10-1838
2-cyanopyridin-3-yl
H
H
H
F
H
H
I
Et
nonafluoro-2-butyl
Br
CF3


10-1841
6-bromopyridin-3-yl
H
H
H
F
H
H
I
n-Pr
nonafluoro-2-butyl
Cl
CF3


10-1842
6-iodopyridin-3-yl
H
H
H
F
H
H
I
n-Pr
nonafluoro-2-butyl
Br
CF3


10-1845
6-cyanopyridin-3-yl
H
H
H
F
H
H
I
i-Pr
nonafluoro-2-butyl
Cl
CF3


10-1846
5-fluoropyridin-3-yl
n-Pr
C(O)Me
H
F
H
H
I
i-Pr
nonafluoro-2-butyl
Br
CF3


10-1849
5-iodopyridin-3-yl
H
H
H
F
H
H
I
n-Bu
nonafluoro-2-butyl
Cl
CF3


10-1850
5-(trifluoromethyl) pyridin-3-yl
H
H
H
F
H
H
I
n-Bu
nonafluoro-2-butyl
Br
CF3


10-1853
4-fluoropyridin-3-yl
H
H
H
F
H
H
I
i-Bu
nonafluoro-2-butyl
Cl
CF3


10-1854
4-chloropyridin-3-yl
H
H
H
F
H
H
I
i-Bu
nonafluoro-2-butyl
Br
CF3


10-1857
4-(trifluoromethyl) pyridin-3-yl
H
H
H
F
H
H
I
s-Bu
nonafluoro-2-butyl
Cl
CF3


10-1858
4-nitropyridin-3-yl
i-Pr
C(O)Me
H
F
H
H
I
s-Bu
nonafluoro-2-butyl
Br
CF3


10-1898
2-iodopyridin-3-yl
H
H
H
F
H
H
OCF3
Me
nonafluoro-2-butyl
Me
OCF3


10-2011
3-bromophenyl
H
Et
H
F
H
H
OCF3
F
heptafluoroisopropyl
F
CF3


10-2041
2-iodopyridin-3-yl
H
H
H
F
H
H
OCF3
Me
nonafluoro-2-butyl
Me
CF3


10-2154
3-bromophenyl
H
Et
H
F
H
H
CF3
F
heptafluoroisopropyl
F
CF3


10-2184
2-iodopyridin-3-yl
H
H
H
F
H
H
CF3
Me
nonafluoro-2-butyl
Me
CF3


10-2297
3-bromophenyl
H
Et
H
F
H
H
Cl
F
heptafluoroisopropyl
F
Cl


10-2327
2-iodopyridin-3-yl
H
H
H
F
H
H
Cl
Me
nonafluoro-2-butyl
Me
I


10-2440
3-bromophenyl
H
Et
H
F
H
H
Cl
F
heptafluoroisopropyl
F
OCF3


10-2470
2-iodopyridin-3-yl
H
H
F
F
H
H
Cl
Me
nonafluoro-2-butyl
Me
OCF3


10-2584
4-bromophenyl
H
H
F
F
H
H
Cl
F
heptafluoroisopropyl
Cl
OF3


10-2594
2-cyanophenyl
n-Pr
n-Pr
F
F
H
H
Cl
Br
pentafluoroethyl
I
CF3


10-2599
2,4-dichlorophenyl
H
H
F
F
H
H
Cl
Me
nonafluoro-2-butyl
H
CF3


10-2600
2-chloro-4-fluorophenyl
H
H
F
F
H
H
Cl
H
nonafluoro-2-butyl
Me
CF3


10-2613
2-iodopyridin-3-yl
H
H
F
F
H
H
Cl
Me
nonafluoro-2-butyl
Me
n-C3F7


10-2614
2-(trifluoromethyl) pyridin-3-yl
H
H
F
F
H
H
Cl
Me
nonafluoro-2-butyl
Et
i-C3F7


10-2620
6-iodopyridin-3-yl
H
H
F
F
H
H
Cl
Et
nonafluoro-2-butyl
Me
n-C3F7


10-2621
6-(trifluoromethyl) pyridin-3-yl
H
H
F
F
H
H
Cl
Et
nonafluoro-2-butyl
Et
i-C3F7


10-2627
5-bromopyridin-3-yl
H
H
F
F
H
H
Br
n-Pr
heptafluoroisopropyl
Me
CF3


10-2628
5-iodopyridin-3-yl
H
H
F
F
H
H
Br
n-Pr
heptafluoroisopropyl
Et
CF3


10-2634
4-bromopyridin-3-yl
Me
n-Pr
F
F
H
H
Br
i-Pr
heptafluoroisopropyl
Me
CF3


10-2635
4-iodopyridin-3-yl
H
H
F
F
H
H
Br
i-Pr
heptafluoroisopropyl
Et
CF3


10-2641
pyridin-4-yl
H
H
F
F
H
H
Br
n-Bu
heptafluoroisopropyl
Me
CF3


10-2642
2-chloropyridin-4-yl
H
H
F
F
H
H
Br
n-Bu
heptafluoroisopropyl
Et
CF3


10-2648
pyridin-2-yl
H
H
F
F
H
H
Br
i-Bu
nonafluoro-2-butyl
Me
CF3


10-2649
3-chloropyridin-2-yl
H
H
F
F
H
H
Br
i-Bu
nonafluoro-2-butyl
Et
CF3


10-2655
2-fluorophenyl
H
H
F
F
H
H
Br
s-Bu
nonafluoro-2-butyl
Me
CF3


10-2656
3-fluorophenyl
H
H
F
F
H
H
Br
s-Bu
nonafluoro-2-butyl
Et
CF3


10-2662
3-bromophenyl
H
H
F
F
H
H
Br
F
nonafluoro-2-butyl
Me
CF3


10-2663
4-bromophenyl
H
H
F
F
H
H
Br
F
nonafluoro-2-butyl
Et
CF3


10-2669
(4-fluoromethyl) phenyl
Et
i-Pr
F
F
H
H
Br
Cl
nonafluoro-2-butyl
Me
CF3


10-2670
2-nitrophenyl
H
H
F
F
H
H
Br
Cl
nonafluoro-2-butyl
Et
CF3


10-2676
4-cyanophenyl
H
H
F
F
H
H
I
Br
heptafluoroisopropyl
Me
CF3


10-2677
2,6-difluorophenyl
H
H
F
F
H
H
I
Br
heptafluoroisopropyl
Et
CF3


10-2683
2-bromo-4-chlorophenyl
n-Pr
Me
F
F
H
H
I
I
heptafluoroisopropyl
Me
CF3


10-2684
2-bromo-4-fluorophenyl
H
H
F
F
H
H
I
I
heptafluoroisopropyl
Et
CF3


10-2690
2-fluoropyridin-3-yl
H
H
F
F
H
H
I
Me
heptafluoroisopropyl
F
C2F5


10-2691
2-chloropyridin-3-yl
H
H
F
F
H
H
I
Me
nonafluoro-2-butyl
Cl
CF3


10-2694
2-(trifluoromethyl) pyridin-3-yl
H
H
F
F
H
H
I
Et
nonafluoro-2-butyl
F
CF3


10-2695
2-nitropyridin-3-yl
H
H
F
F
H
H
I
Et
nonafluoro-2-butyl
Cl
CF3


10-2698
6-chloropyridin-3-yl
H
H
F
F
H
H
I
n-Pr
nonafluoro-2-butyl
F
CF3


10-2699
6-bromopyridin-3-yl
H
H
F
F
H
H
I
n-Pr
nonafluoro-2-butyl
Cl
CF3


10-2702
6-nitropyridin-3-yl
H
H
F
F
H
H
I
i-Pr
nonafluoro-2-butyl
F
i-C3F7


10-2703
6-cyanopyridin-3-yl
H
H
F
F
H
H
I
i-Pr
nonafluoro-2-butyl
Cl
CF3


10-2706
5-bromopyridin-3-yl
H
H
F
F
H
H
I
n-Bu
nonafluoro-2-butyl
F
CF3


10-2707
5-iodopyridin-3-yl
H
H
F
F
H
H
I
n-Bu
nonafluoro-2-butyl
Cl
CF3


10-2710
5-cyanopyridin-3-yl
H
H
F
F
H
H
I
i-Bu
nonafluoro-2-butyl
F
CF3


10-2711
4-fluoropyridin-3-yl
H
H
F
F
H
H
I
i-Bu
nonafluoro-2-butyl
Cl
CF3


10-2714
4-iodopyridin-3-yl
i-Pr
n-Pr
F
F
H
H
I
s-Bu
nonafluoro-2-butyl
F
CF3


10-2715
4-(fluoromethyl) pyridin-3-yl
H
H
F
F
H
H
I
s-Bu
nonafluoro-2-butyl
Cl
CF3


10-2726
3-bromophenyl
H
Et
F
F
H
H
OCF3
F
heptafluoroisopropyl
F
OCF3


10-2756
2-iodopyridin-3-yl
H
H
F
F
H
H
OCF3
Me
nonafluoro-2-butyl
Me
OCF3


10-2869
3-bromophenyl
H
H
F
F
H
H
OCF3
F
heptafluoroisopropyl
F
CF3


10-2899
2-iodopyridin-3-yl
H
H
F
F
H
H
OCF3
Me
nonafluoro-2-butyl
Me
CF3


10-3012
3-bromophenyl
H
H
F
F
H
H
CF3
F
heptafluoroisopropyl
F
CF3


10-3042
2-iodopyridin-3-yl
H
H
F
F
H
H
CF3
Me
nonafluoro-2-butyl
Me
CF3


10-3147
phenyl
H
H
F
F
F
H
Cl
F
pentafluoroethyl
H
Cl


10-3168
phenyl
H
H
H
H
F
H
Cl
I
pentafluoroethyl
Cl
Cl


10-3189
phenyl
H
H
H
H
H
F
Cl
Me
pentafluoroethyl
n-Bu
Cl


10-3198
phenyl
H
H
F
H
F
H
Cl
Et
pentafluoroethyl
s-Bu
Cl


10-3218
phenyl
H
H
F
H
H
F
Cl
n-Bu
pentafluoroethyl
i-Bu
Cl


10-3227
phenyl
H
H
H
F
F
H
Cl
s-Bu
pentafluoroethyl
Me
Cl


10-3236
phenyl
H
H
H
F
H
F
Cl
F
pentafluoroethyl
N-pr
Cl


10-3245
phenyl
H
H
H
H
F
F
Cl
Cl
pentafluoroethyl
n-Bu
Cl


10-3254
phenyl
H
H
F
F
H
F
Cl
Br
pentafluoroethyl
s-Bu
Cl


10-3263
phenyl
H
H
F
H
F
F
Cl
Me
pentafluoroethyl
Cl
Cl


10-3272
phenyl
H
H
H
F
F
F
Cl
n-Pr
pentafluoroethyl
Br
Cl


10-3281
phenyl
i-Pr
Me
F
F
F
F
Cl
n-Bu
pentafluoroethyl
I
Cl











embedded image





















TABLE 11





compound














number
Q2
R1
R2
X1
X2
X3
X4
Y1
Y2
Y3
Y4
Y5







11-1
2,2,2-trichloroethyl
H
H
H
H
H
H
F
H
heptafluoroisopropyl
H
OCF3


11-2
2,2,2-trichloroethyl
H
H
H
H
H
H
F
H
nonafluoro-2-butyl
H
OCF3


11-13
2,2,2-trichloroethyl
H
H
H
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


11-42
2,2,2-trichloroethyl
H
H
H
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


11-71
2,2,2-trichloroethyl
H
H
H
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


11-100
2,2,2-trichloroethyl
H
H
H
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


11-129
2,2,2-trichloroethyl
H
H
H
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


11-158
2,2,2-trichloroethyl
H
H
H
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


11-189
2,2,2-trichloroethyl
H
H
H
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


11-218
2,2,2-trichloroethyl
H
H
H
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


11-247
2,2,2-trichloroethyl
H
H
H
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


11-260
4,4,4-trifluoro-n-butyl
H
H
H
H
H
H
Br
H
pentafluoroethyl
H
CF3


11-276
2,2,2-trichloroethyl
H
H
H
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


11-289
4,4,4-trifluoro-n-butyl
H
H
H
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


11-305
2,2,2-trichloroethyl
H
H
H
H
H
H
I
H
heptafluoroisopropyl
H
CF3


11-318
4,4,4-trifluoro-n-butyl
H
H
H
H
H
H
I
H
heptafluoroisopropyl
H
C2F5


11-334
2,2,2-trichloroethyl
H
H
H
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


11-347
4,4,4-trifluoro-n-butyl
H
H
H
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


11-363
2,2,2-trichloroethyl
H
H
H
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


11-392
2,2,2-tnchloroethyl
H
H
H
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


11-421
2,2,2-trichloroethyl
H
H
H
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


11-450
2,2,2-trichloroethyl
H
H
H
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


11-479
2,2,2-trichloroethyl
H
H
H
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


11-508
2,2,2-trichloroethyl
H
H
H
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


11-527
2,2,2-trichloroethyl
H
H
F
H
H
H
F
H
heptafluoroisopropyl
H
F


11-528
2,2,2-trichloroethyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


11-529
2,2,2-trichloroethyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
Br


11-530
2,2,2-trichloroethyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
I


11-531
2,2,2-trichloroethyl
H
H
F
H
H
H
F
H
heptafluoroisopropyl
H
OCF3


11-532
2,2,2-trichloroethyl
H
H
F
H
H
H
F
H
nonafluoro-2-butyl
H
OCF3


11-543
2,2,2-trichloroethyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


11-556
4,4,4-trifluoro-n-butyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


11-572
2,2,2-trichloroethyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


11-585
4,4,4-trifluoro-n-butyl
H
H
F
H
H
H
Cl
H
pentafluoroethyl
H
OCF3


11-591
methyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


11-592
ethyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


11-593
2-fluoroethyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


11-594
2-chloroethyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


11-595
2-bromoethyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


11-596
2-iodoethyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
OC2F5


11-597
2-cyanoethyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


11-598
2,2-difluoroethyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


11-599
2,2-dichloroethyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


11-600
2,2,2-trifluoroethyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


11-601
2,2,2-trichloroethyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


11-602
2,2,2-tribromoethyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


11-603
n-propyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


11-604
3-fluoro-n-propyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


11-605
3-chloro-n-propyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


11-606
3-bromo-n-propyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


11-607
i-propyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


11-608
1,2-difluoro-2-propyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


11-609
1,3-difluoro-2-propyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


11-610
1,3-dichloro-2-propyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


11-611
1-chloro-3-fluoro-2-propyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


11-612
3,3,3-trifluoro-n-propyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


11-613
n-butyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


11-614
4,4,4-trifluoro-n-butyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


11-615
i-butyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


11-616
s-butyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


11-617
vinyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


11-618
benzyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


11-619
phenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


11-620
methyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


11-621
ethyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


11-622
2-fluoroethyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


11-623
2-chloroethyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


11-624
2-bromoethyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


11-625
2-iodoethyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


11-626
2-cyanoethyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


11-627
2,2-difluoroethyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


11-628
2,2-dichloroethyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


11-629
2,2,2-trifluoroethyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


11-630
2,2,2-trichloroethyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


11-631
2,2,2-tribromoethyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


11-632
n-propyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
OC2F5


11-633
3-fluoro-n-propyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


11-634
3-chloro-n-propyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


11-635
3-bromo-n-propyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


11-636
i-propyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


11-637
1,2-difluoro-2-propyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


11-638
1,3-difluoro-2-propyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


11-639
1,3-dichloro-2-propyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


11-640
1-chloro-3-fluoro-2-propyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


11-641
3,3,3-trifluoro-n-propyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


11-642
n-butyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


11-643
4,4,4-trifluoro-n-butyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


11-644
i-butyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


11-645
s-butyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


11-646
vinyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


11-647
benzyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


11-648
phenyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


11-649
methyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


11-650
ethyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


11-651
2-fluoroethyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


11-652
2-chloroethyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


11-653
2-bromoethyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


11-654
2-iodoethyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


11-655
2-cyanoethyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


11-656
2,2-difluoroethyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


11-657
2,2-dichloroethyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


11-658
2,2,2-trifluoroethyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


11-659
2,2,2-trichloroethyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


11-660
2,2,2-tribromoethyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


11-661
n-propyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


11-662
3-fluoro-n-propyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


11-663
3-chloro-n-propyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
OC2F5


11-664
3-bromo-n-propyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


11-665
i-propyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


11-666
1,2-difluoro-2-propyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


11-667
1,3-difluoro-2-propyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


11-668
1,3-dichloro-2-propyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


11-669
1-chloro-3-fluoro-2-propyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


11-670
3,3,3-trifluoro-n-propyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


11-671
n-butyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


11-672
4,4,4-trifluoro-n-butyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


11-673
i-butyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


11-674
s-butyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


11-675
vinyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


11-676
benzyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


11-677
phenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


11-678
methyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


11-679
ethyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


11-680
2-fluoroethyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


11-681
2-chloroethyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


11-682
2-bromoethyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


11-683
2-iodoethyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


11-684
2-cyanoethyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


11-685
2,2-difluoroethyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


11-686
2,2-dichloroethyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


11-687
2,2,2-trifluoroethyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


11-688
2,2,2-trichloroethyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


11-689
2,2,2-tribromoethyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


11-690
n-propyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


11-691
3-fluoro-n-propyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


11-692
3-chloro-n-propyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


11-693
3-bromo-n-propyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


11-694
i-propyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


11-695
1,2-difluoro-2-propyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


11-696
1,3-difluoro-2-propyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


11-697
12-dichloro-2-propyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


11-698
1-chloro-3-fluoro-2-propyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


11-699
3,3,3-trifluoro-n-propyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


11-700
n-butyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


11-701
4,4,4-trifluoro-n-butyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


11-702
i-butyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


11-703
s-butyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


11-704
vinyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


11-705
benzyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
OC2F5


11-706
phenyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


11-707
2,2,2-trichloroethyl
H
H
F
H
H
H
F
H
heptafluoroisopropyl
H
CF3


11-708
2,2,2-trichloroethyl
H
H
F
H
H
H
F
H
nonafluoro-2-butyl
H
CF3


11-709
methyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


11-710
ethyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


11-711
2-fluoroethyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


11-712
2-chloroethyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


11-713
2-bromoethyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


11-714
2-iodoethyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


11-715
2-cyanoethyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
C2F5


11-716
2,2-difluoroethyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


11-717
2,2-dichloroethyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


11-718
2,2,2-trifluoroethyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


11-719
2,2,2-trichloroethyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


11-720
2,2,2-tribromoethyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


11-721
n-propyl
H
H
F
H
H
H
Cl
H
pentafluoroethyl
H
CF3


11-722
3-fluoro-n-propyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


11-723
3-chloro-n-propyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


11-724
3-bromo-n-propyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


11-725
i-propyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


11-726
1,2-difluoro-2-propyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


11-727
1,3-difluoro-2-propyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


11-728
1,3-dichloro-2-propyl
H
H
F
H
H
H
Cl
H
pentafluoroethyl
H
CF3


11-729
1-chloro-3-fluoro-2-propyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


11-730
3,3,3-trifluoro-n-propyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


11-731
n-butyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


11-732
4,4,4-trifluoro-n-butyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


11-733
i-butyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


11-734
s-butyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


11-735
vinyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


11-736
benzyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


11-737
phenyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


11-738
methyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


11-739
ethyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


11-740
2-fluoroethyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


11-741
2-chloroethyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


11-742
2-bromoethyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


11-743
2-iodoethyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


11-744
2-cyanoethyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


11-745
2,2-difluoroethyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


11-746
2,2-dichloroethyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


11-747
2,2,2-trifluoroethyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


11-748
2,2,2-trichloroethyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


11-749
2,2,2-tribromoethyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


11-750
n-propyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


11-751
3-fluoro-n-propyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


11-752
3-chloro-n-propyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


11-753
3-bromo-n-propyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


11-754
i-propyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


11-755
1,2-difluoro-2-propyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


11-756
1,3-difluoro-2-propyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


11-757
1,3-dichloro-2-propyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


11-758
1-chloro-3-fluoro-2-propyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


11-759
3,3,3-trifluoro-n-propyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


11-760
n-butyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


11-761
4,4,4-trifluoro-n-butyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


11-762
i-butyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


11-763
s-butyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


11-764
vinyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


11-765
benzyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


11-766
phenyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


11-767
methyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


11-768
ethyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


11-769
2-fluoroethyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


11-770
2-chloroethyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


11-771
2-bromoethyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


11-772
2-iodoethyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


11-773
2-cyanoethyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
C2F5


11-774
2,2-difluoroethyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


11-775
2,2-dichloroethyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


11-776
2,2,2-trifluoroethyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


11-777
2,2,2-trichloroethyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


11-778
2,2,2-tribromoethyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


11-779
n-propyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


11-780
3-fluoro-n-propyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


11-781
3-chloro-n-propyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


11-782
3-bromo-n-propyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


11-783
1-propyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


11-784
1,2-difluoro-2-propyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
n-C3F7


11-785
1,3-difluoro-2-propyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


11-786
1,3-dichloro-2-propyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


11-787
1-chloro-3-fluoro-2-propyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


11-788
3,3,3-fluoro-n-propyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


11-789
n-butyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


11-790
4,4,4-trifluoro-n-butyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


11-791
i-butyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


11-792
s-butyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


11-793
vinyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


11-794
benzyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


11-795
phenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


11-796
methyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


11-797
ethyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


11-798
2-fluoroethyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


11-799
2-chloroethyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


11-800
2-bromoethyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


11-801
2-iodoethyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


11-802
2-cyanoethyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


11-803
2,2-difluoroethyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


11-804
2,2-dichloroethyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


11-805
2,2,2-trifluoroethyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


11-806
2,2,2-trichloroethyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


11-807
2,2,2-tribromoethyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


11-808
n-propyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


11-809
3-fluoro-n-propyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


11-810
3-chloro-n-propyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


11-811
3-bromo-n-propyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


11-812
i-propyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


11-813
1,2-difluoro-2-propyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


11-814
1,3-difluoro-2-propyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


11-815
1,3-dichloro-2-propyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


11-816
1-chloro-3-fluoro-2-propyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


11-817
3,3,3-trifluoro-n-propyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


11-818
n-butyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


11-819
4,4,4-trifluoro-n-butyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


11-820
i-butyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


11-821
s-butyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


11-822
vinyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


11-823
benzyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


11-824
phenyl
H
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
i-C3F7


11-825
methyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


11-826
ethyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


11-827
2-fluoroethyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


11-828
2-chloroethyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


11-829
2-bromoethyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


11-830
2-iodoethyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


11-831
2-cyanoethyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


11-832
2,2-difluoroethyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


11-833
2,2-dichloroethyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


11-834
2,2,2-trifluoroethyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


11-835
2,2,2-trichloroethyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


11-836
2,2,2-tribromoethyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


11-837
n-propyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


11-838
3-fluoro-n-propyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


11-839
3-chloro-n-propyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


11-840
3-bromo-n-propyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
C2F5


11-841
i-propyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


11-842
1,2-difluoro-2-propyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


11-843
1,3-difluoro-2-propyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


11-844
1,3-dichloro-2-propyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


11-845
1-chloro-3-fluoro-2-propyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


11-846
3,3,3-trifluoro-n-propyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


11-847
n-butyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


11-848
4,4,4-trifluoro-n-butyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


11-849
i-butyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


11-850
s-butyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


11-851
vinyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


11-852
benzyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


11-853
phenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


11-854
methyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


11-855
ethyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


11-856
2-fluoroethyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


11-857
2-chloroethyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


11-858
2-bromoethyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


11-859
2-iodoethyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


11-860
2-cyanoethyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


11-861
2,2-difluoroethyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


11-862
2,2-dichloroethyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


11-863
2,2,2-trifluoroethyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


11-864
2,2,2-trichloroethyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


11-865
2,2,2-tribromoethyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


11-866
n-propyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


11-867
3-fluoro-n-propyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


11-868
3-chloro-n-propyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


11-869
3-bromo-n-propyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


11-870
i-propyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


11-871
1,2-difluoro-2-propyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


11-872
1,3-difluoro-2-propyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


11-873
1,3-dichloro-2-propyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


11-874
1-chloro-3-fluoro-2-propyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


11-875
3,3,3-trifluoro-n-propyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


11-876
n-butyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


11-877
4,4,4-trifluoro-n-butyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


11-878
i-butyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


11-879
s-butyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


11-880
vinyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
i-C3F7


11-881
benzyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


11-882
phenyl
H
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


11-893
2,2,2-trichloroethyl
H
H
F
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


11-922
2,2,2-trichloroethyl
H
H
F
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


11-951
2,2,2-trichloroethyl
H
H
F
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


11-980
2,2,2-trichloroethyl
H
H
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


11-999
methyl
H
H
F
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


11-1000
ethyl
H
H
F
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


11-1001
2-fluoroethyl
H
H
F
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


11-1002
2-chloroethyl
H
H
F
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


11-1003
2-bromoethyl
H
H
F
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


11-1004
2-iodoethyl
H
H
F
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


11-1005
2-cyanoethyl
H
H
F
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


11-1006
2,2-difluoroethyl
H
H
F
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


11-1007
2,2-dichloroethyl
H
H
F
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


11-1008
2,2,2-trifluoroethyl
H
H
F
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


11-1009
2,2,2-trichloroethyl
H
H
F
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


11-1010
2,2,2-tribromoethyl
H
H
F
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


11-1011
n-propyl
H
H
F
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


11-1012
3-fluoro-n-propyl
H
H
F
H
H
H
C2F5
H
heptafluoroisopropyl
H
CF3


11-1013
3-chloro-n-propyl
H
H
F
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


11-1014
3-bromo-n-propyl
H
H
F
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


11-1015
i-propyl
H
H
F
H
H
H
i-C3F7
H
heptafluoroisopropyl
H
CF3


11-1016
1,2-difluoro-2-propyl
H
H
F
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


11-1017
1,3-di6uoro-2-propyl
H
H
F
H
H
H
CF3
H
pentafluoroethyl
H
CF3


11-1018
1,3-dichloro-2-propyl
H
H
F
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


11-1019
1-chloro-3-fluoro-2-propyl
H
H
F
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


11-1020
3,3,3-trifluoro-n-propyl
H
H
F
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


11-1021
n-butyl
H
H
F
H
H
H
C2F5
H
heptafluoroisopropyl
H
C2F5


11-1022
4,4,4-trifluoro-n-butyl
H
H
F
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


11-1023
i-butyl
H
H
F
H
H
H
C2F5
H
heptafluoroisopropyl
H
n-C3F7


11-1024
s-butyl
H
H
F
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


11-1025
vinyl
H
H
F
H
H
H
n-C3F7
H
heptafluoroisopropyl
H
CF3


11-1026
benzyl
H
H
F
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


11-1027
phenyl
H
H
F
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


11-1030
2-fluoroethyl
H
H
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


11-1031
2-chloroethyl
H
H
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


11-1032
2-bromoethyl
H
H
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


11-1033
2-iodoethyl
H
H
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


11-1035
2,2-difluoroethyl
H
H
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


11-1036
2,2-dichloroethyl
H
H
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


11-1037
2,2,2-trifluoroethyl
H
H
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


11-1038
2,2,2-trichloroethyl
H
H
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


11-1039
2,2,2-tribromoethyl
H
H
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


11-1041
3-fluoro-n-propyl
H
H
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


11-1042
3-chloro-n-propyl
H
H
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


11-1043
3-bromo-n-propyl
H
H
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


11-1045
1,2-difluoro-2-propyl
H
H
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


11-1046
1,3-difluoro-2-propyl
H
H
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


11-1047
1,3-dichloro-2-propyl
H
H
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


11-1048
1-chloro-3-fluoro-2-propyl
H
H
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


11-1049
3,3,3-trifluoro-n-propyl
H
H
F
H
H
H
n-C3F7
H
nonafluoro-2-butyl
H
i-C3F7


11-1051
4,4,4-trifluoro-n-butyl
H
H
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


11-1057
2,2,2-trichloroethyl
H
H
H
F
H
H
F
H
heptafluoroisopropyl
H
F


11-1058
2,2,2-trichloroethyl
H
H
H
F
H
H
F
H
nonafluoro-2-butyl
H
F


11-1069
2,2,2-trichloroethyl
H
H
H
F
H
H
Cl
H
heptafluoroisopropyl
H
Cl


11-1098
2,2,2-trichloroethyl
H
H
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


11-1127
2,2,2-trichloroethyl
H
H
H
F
H
H
Br
H
heptafluoroisopropyl
H
Br


11-1156
2,2,2-trichloroethyl
H
H
H
F
H
H
Br
H
nonafluoro-2-butyl
H
Br


11-1185
2,2,2-trichloroethyl
H
H
H
F
H
H
I
H
heptafluoroisopropyl
H
I


11-1214
2,2,2-trichloroethyl
H
H
H
F
H
H
I
H
nonafluoro-2-butyl
H
I


11-1233
2,2,2-trichloroethyl
H
H
H
F
H
H
F
H
heptafluoroisopropyl
H
Cl


11-1234
2,2,2-trichloroethyl
H
H
H
F
H
H
F
H
heptafluoroisopropyl
H
Br


11-1235
2,2,2-trichloroethyl
H
H
H
F
H
H
F
H
heptafluoroisopropyl
H
I


11-1236
2,2,2-trichloroethyl
H
H
H
F
H
H
Cl
H
heptafluoroisopropyl
H
Br


11-1237
2,2,2-trichloroethyl
H
H
H
F
H
H
Cl
H
heptafluoroisopropyl
H
I


11-1238
2,2,2-trichloroethyl
H
H
H
F
H
H
Br
H
heptafluoroisopropyl
H
I


11-1239
2,2,2-trichloroethyl
H
H
H
F
H
H
F
H
nonafluoro-2-butyl
H
Cl


11-1240
2,2,2-trichloroethyl
H
H
H
F
H
H
F
H
nonafluoro-2-butyl
H
Br


11-1241
2,2,2-trichloroethyl
H
H
H
F
H
H
F
H
nonafluoro-2-butyl
H
I


11-1242
2,2,2-trichloroethyl
H
H
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
Br


11-1243
2,2,2-trichloroethyl
H
H
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
I


11-1244
2,2,2-trichloroethyl
H
H
H
F
H
H
Br
H
nonafluoro-2-butyl
H
I


11-1245
2,2,2-trichloroethyl
H
H
H
F
H
H
F
H
heptafluoroisopropyl
H
OCF3


11-1246
2,2,2-trichloroethyl
H
H
H
F
H
H
F
H
nonafluoro-2-butyl
H
OCF3


11-1257
2,2,2-trichloroethyl
H
H
H
F
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


11-1286
2,2,2-trichloroethyl
H
H
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


11-1315
2,2,2-trichloroethyl
H
H
H
F
H
H
Br
H
heptafluoroisopropyl
H
OCF3


11-1344
2,2,2-trichloroethyl
H
H
H
F
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


11-1373
2,2,2-trichloroethyl
H
H
H
F
H
H
I
H
heptafluoroisopropyl
H
OCF3


11-1402
2,2,2-trichloroethyl
H
H
H
F
H
H
I
H
nonafluoro-2-butyl
H
OCF3


11-1421
2,2,2-trichloroethyl
H
H
H
F
H
H
F
H
heptafluoroisopropyl
H
CF3


11-1422
2,2,2-trichloroethyl
H
H
H
F
H
H
F
H
nonafluoro-2-butyl
H
CF3


11-1433
2,2,2-trichloroethyl
H
H
H
F
H
H
Cl
H
heptafluoroisopropyl
H
CF3


11-1461
2,2,2-trifluoroethyl
H
H
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


11-1491
2,2,2-trichloroethyl
H
H
H
F
H
H
Br
H
heptafluoroisopropyl
H
CF3


11-1504
4,4,4-trifluoro-n-butyl
H
H
H
F
H
H
Br
H
heptafluoroisopropyl
H
CF3


11-1520
2,2,2-trichloroethyl
H
H
H
F
H
H
Br
H
nonafluoro-2-butyl
H
CF3


11-1533
4,4,4-trifluoro-n-butyl
H
H
H
F
H
H
Br
H
nonafluoro-2-butyl
H
CF3


11-1548
2,2,2-trifluoroethyl
H
H
H
F
H
H
I
H
heptafluoroisopropyl
H
CF3


11-1562
4,4,4-trifluoro-n-butyl
H
H
H
F
H
H
I
H
heptafluoroisopropyl
H
CF3


11-1578
2,2,2-trichloroethyl
H
H
H
F
H
H
I
H
nonafluoro-2-butyl
H
CF3


11-1591
4,4,4-trifluoro-n-butyl
H
H
H
F
H
H
I
H
nonafluoro-2-butyl
H
CF3


11-1607
2,2,2-trichloroethyl
H
H
H
F
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


11-1636
2,2,2-trichloroethyl
H
H
H
F
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


11-1665
2,2,2-trichloroethyl
H
H
H
F
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


11-1694
2,2,2-trichloroethyl
H
H
H
F
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


11-1723
2,2,2-trichloroethyl
H
H
H
F
H
H
CF3
H
heptafluoroisopropyl
H
CF3


11-1752
2,2,2-trichloroethyl
H
H
H
F
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


11-1771
2,2,2-trichloroethyl
H
H
F
F
H
H
F
H
heptafluoroisopropyl
H
F


11-1772
2,2,2-trichloroethyl
H
H
F
F
H
H
F
H
nonafluoro-2-butyl
H
F


11-1783
2,2,2-trichloroethyl
H
H
F
F
H
H
Cl
H
heptafluoroisopropyl
H
Cl


11-1812
2,2,2-trichloroethyl
H
H
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


11-1841
2,2,2-trichloroethyl
H
H
F
F
H
H
Br
H
heptafluoroisopropyl
H
Br


11-1870
2,2,2-trichloroethyl
H
H
F
F
H
H
Br
H
nonafluoro-2-butyl
H
Br


11-1899
2,2,2-trichloroethyl
H
H
F
F
H
H
I
H
heptafluoroisopropyl
H
I


11-1928
2,2,2-trichloroethyl
H
H
F
F
H
H
I
H
nonafluoro-2-butyl
H
I


11-1947
2,2,2-trichloroethyl
H
H
F
F
H
H
F
H
heptafluoroisopropyl
H
Cl


11-1948
2,2,2-trichloroethyl
H
H
F
F
H
H
F
H
heptafluoroisopropyl
H
Br


11-1949
2,2,2-trichloroethyl
H
H
F
F
H
H
F
H
heptafluoroisopropyl
H
I


11-1950
2,2,2-trichloroethyl
H
H
F
F
H
H
Cl
H
heptafluoroisopropyl
H
Br


11-1951
2,2,2-trichloroethyl
H
H
F
F
H
H
Cl
H
heptafluoroisopropyl
H
I


11-1952
2,2,2-trichloroethyl
H
H
F
F
H
H
Br
H
heptafluoroisopropyl
H
I


11-1953
2,2,2-trichloroethyl
H
H
F
F
H
H
F
H
nonafluoro-2-butyl
H
Cl


11-1954
2,2,2-trichloroethyl
H
H
F
F
H
H
F
H
nonafluoro-2-butyl
H
Br


11-1955
2,2,2-trichloroethyl
H
H
F
F
H
H
F
H
nonafluoro-2-butyl
H
I


11-1956
2,2,2-trichloroethyl
H
H
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
Br


11-1957
2,2,2-trichloroethyl
H
H
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
I


11-1958
2,2,2-trichloroethyl
H
H
F
F
H
H
Br
H
nonafluoro-2-butyl
H
I


11-1959
2,2,2-trichloroethyl
H
H
F
F
H
H
F
H
heptafluoroisopropyl
H
OCF3


11-1960
2,2,2-trichloroethyl
H
H
F
F
H
H
F
H
nonafluoro-2-butyl
H
OCF3


11-1971
2,2,2-trichloroethyl
H
H
F
F
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


11-2000
2,2,2-trichloroethyl
H
H
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


11-2029
2,2,2-trichloroethyl
H
H
F
F
H
H
Br
H
heptafluoroisopropyl
H
OCF3


11-2058
2,2,2-trichloroethyl
H
H
F
F
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


11-2087
2,2,2-trichloroethyl
H
H
F
F
H
H
I
H
heptafluoroisopropyl
H
OCF3


11-2116
2,2,2-trichloroethyl
H
H
F
F
H
H
I
H
nonafluoro-2-butyl
H
OCF3


11-2135
2,2,2-trichloroethyl
H
H
F
F
H
H
F
H
heptafluoroisopropyl
H
CF3


11-2136
2,2,2-trichloroethyl
H
H
F
F
H
H
F
H
nonafluoro-2-butyl
H
CF3


11-2147
2,2,2-trichloroethyl
H
H
F
F
H
H
Cl
H
heptafluoroisopropyl
H
CF3


11-2176
2,2,2-trichloroethyl
H
H
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


11-2205
2,2,2-trichloroethyl
H
H
F
F
H
H
Br
H
heptafluoroisopropyl
H
CF3


11-2218
4,4,4-trifluoro-n-butyl
H
H
F
F
H
H
Br
H
heptafluoroisopropyl
H
CF3


11-2234
2,2,2-trichloroethyl
H
H
F
F
H
H
Br
H
nonafluoro-2-butyl
H
CF3


11-2247
4,4,4-trifluoro-n-butyl
H
H
F
F
H
H
Br
H
nonafluoro-2-butyl
H
CF3


11-2263
2,2,2-trichloroethyl
H
H
F
F
H
H
I
H
heptafluoroisopropyl
H
CF3


11-2276
4,4,4-trifluoro-n-butyl
H
H
F
F
H
H
I
H
heptafluoroisopropyl
H
CF3


11-2292
2,2,2-trichloroethyl
H
H
F
F
H
H
I
H
nonafluoro-2-butyl
H
CF3


11-2305
4,4,4-trifluoro-n-butyl
H
H
F
F
H
H
I
H
nonafluoro-2-butyl
H
CF3


11-2321
2,2,2-trichloroethyl
H
H
F
F
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


11-2350
2,2,2-trichloroethyl
H
H
F
F
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


11-2379
2,2,2-trichloroethyl
H
H
F
F
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


11-2408
2,2,2-trichloroethyl
H
H
F
F
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


11-2437
2,2,2-trichloroethyl
H
H
F
F
H
H
CF3
H
heptafluoroisopropyl
H
CF3


11-2466
2,2,2-trichloroethyl
H
H
F
F
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


11-2485
2,2,2-trichloroethyl
H
H
F
F
F
H
Cl
H
pentafluoroethyl
H
Cl


11-2486
2,2,2-trichloroethyl
H
H
F
F
F
H
Br
H
heptafluoroisopropyl
H
Br


11-2487
2,2,2-trichloroethyl
H
H
F
F
F
H
Br
H
heptafluoroisopropyl
H
OCF3


11-2488
2,2,2-trichloroethyl
H
H
F
F
F
H
I
H
heptafluoroisopropyl
H
CF3


11-2489
2,2,2-trichloroethyl
H
H
F
F
F
H
CF3
H
heptafluoroisopropyl
H
CF3


11-2490
2,2,2-trichloroethyl
H
H
F
F
F
H
I
H
nonafluoro-2-butyl
H
I


11-2491
2,2,2-trichloroethyl
H
H
F
F
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


11-2492
2,2,2-trichloroethyl
H
H
F
F
F
H
Br
H
nonafluoro-2-butyl
H
CF3


11-2493
2,2,2-trichloroethyl
H
H
F
F
F
H
CF3
H
nonafluoro-2-butyl
H
CF3


11-2494
2,2,2-trichloroethyl
H
H
H
H
F
H
Cl
H
pentafluoroethyl
H
Cl


11-2495
2,2,2-trichloroethyl
H
H
H
H
F
H
Br
H
heptafluoroisopropyl
H
Br


11-2496
2,2,2-trichloroethyl
H
H
H
H
F
H
Br
H
heptafluoroisopropyl
H
OCF3


11-2497
2,2,2-trichloroethyl
H
H
H
H
F
H
I
H
heptafluoroisopropyl
H
CF3


11-2498
2,2,2-trichloroethyl
H
H
H
H
F
H
CF3
H
heptafluoroisopropyl
H
CF3


11-2499
2,2,2-trichloroethyl
H
H
H
H
F
H
I
H
nonafluoro-2-butyl
H
I


11-2500
2,2,2-trichloroethyl
H
H
H
H
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


11-2501
2,2,2-trichloroethyl
H
H
H
H
F
H
Br
H
nonafluoro-2-butyl
H
CF3


11-2502
2,2,2-trichloroethyl
H
H
H
H
F
H
CF3
H
nonafluoro-2-butyl
H
CF3


11-2503
2,2,2-trichloroethyl
H
H
H
H
H
F
Cl
H
pentafluoroethyl
H
Cl


11-2504
2,2,2-trichloroethyl
H
H
H
H
H
F
Br
H
heptafluoroisopropyl
H
Br


11-2505
2,2,2-trichloroethyl
H
H
H
H
H
F
Br
H
heptafluoroisopropyl
H
OCF3


11-2506
2,2,2-trichloroethyl
H
H
H
H
H
F
I
H
heptafluoroisopropyl
H
CF3


11-2507
2,2,2-trichloroethyl
H
H
H
H
H
F
CF3
H
heptafluoroisopropyl
H
CF3


11-2508
2,2,2-trichloroethyl
H
H
H
H
H
F
I
H
nonafluoro-2-butyl
H
I


11-2509
2,2,2-trichloroethyl
H
H
H
H
H
F
Cl
H
nonafluoro-2-butyl
H
OCF3


11-2510
2,2,2-trichloroethyl
H
H
H
H
H
F
Br
H
nonafluoro-2-butyl
H
CF3


11-2511
2,2,2-trichloroethyl
H
H
H
H
H
F
CF3
H
nonafluoro-2-butyl
H
CF3


11-2512
2,2,2-trichloroethyl
H
H
F
H
F
H
Cl
H
pentafluoroethyl
H
Cl


11-2513
2,2,2-trichloroethyl
H
H
F
H
F
H
Br
H
heptafluoroisopropyl
H
Br


11-3514
2,2,2-trichloroethyl
H
H
F
H
F
H
Br
H
heptafluoroisopropyl
H
OCF3


11-2515
2,2,2-trichloroethyl
H
H
F
H
F
H
I
H
heptafluoroisopropyl
H
CF3


11-2516
2,2,2-trichloroethyl
H
H
F
H
F
H
CF3
H
heptafluoroisopropyl
H
CF3


11-2517
2,2,2-trichloroethyl
H
H
F
H
F
H
I
H
nonafluoro-2-butyl
H
I


11-2518
2,2,2-trichloroethyl
H
H
F
H
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


11-2519
2,2,2-trichloroethyl
H
H
F
H
F
H
Br
H
nonafluoro-2-butyl
H
CF3


11-2520
2,2,2-trichloroethyl
H
H
F
H
F
H
CF3
H
nonafluoro-2-butyl
H
CF3


11-2521
2,2,2-trichloroethyl
H
H
F
H
H
F
Cl
H
pentafluoroethyl
H
Cl


11-2522
2,2,2-trichloroethyl
H
H
F
H
H
F
Br
H
heptafluoroisopropyl
H
Br


11-2523
2,2,2-trichloroethyl
H
H
F
H
H
F
Br
H
heptafluoroisopropyl
H
OCF3


11-2524
2,2,2-trichloroethyl
H
H
F
H
H
F
I
H
heptafluoroisopropyl
H
CF3


11-2525
2,2,2-trichloroethyl
H
H
F
H
H
F
CF3
H
heptafluoroisopropyl
H
CF3


11-2526
2,2,2-trichloroethyl
H
H
F
H
H
F
I
H
nonafluoro-2-butyl
H
I


11-2527
2,2,2-trichloroethyl
H
H
F
H
H
F
Cl
H
nonafluoro-2-butyl
H
OCF3


11-2528
2,2,2-trichloroethyl
H
H
F
H
H
F
Br
H
nonafluoro-2-butyl
H
CF3


11-2529
2,2,2-trichloroethyl
H
H
F
H
H
F
CF3
H
nonafluoro-2-butyl
H
CF3


11-2530
2,2,2-trichloroethyl
H
H
H
F
F
H
Cl
H
pentafluoroethyl
H
Cl


11-2531
2,2,2-trichloroethyl
H
H
H
F
F
H
Br
H
heptafluoroisopropyl
H
Br


11-2532
2,2,2-trichloroethyl
H
H
H
F
F
H
Br
H
heptafluoroisopropyl
H
OCF3


11-2533
2,2,2-trichloroethyl
H
H
H
F
F
H
I
H
heptafluoroisopropyl
H
CF3


11-2534
2,2,2-trichloroethyl
H
H
H
F
F
H
CF3
H
heptafluoroisopropyl
H
CF3


11-2535
2,2,2-trichloroethyl
H
H
H
F
F
H
I
H
nonafluoro-2-butyl
H
I


11-2536
2,2,2-trichloroethyl
H
H
H
F
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


11-2537
2,2,2-trichloroethyl
H
H
H
F
F
H
Br
H
nonafluoro-2-butyl
H
CF3


11-2538
2,2,2-trichloroethyl
H
H
H
F
F
H
CF3
H
nonafluoro-2-butyl
H
CF3


11-2539
2,2,2-trichloroethyl
H
H
H
F
H
F
Cl
H
pentafluoroethyl
H
Cl


11-2540
2,2,2-trichloroethyl
H
H
H
F
H
F
Br
H
heptafluoroisopropyl
H
Br


11-2541
2,2,2-trichloroethyl
H
H
H
F
H
F
Br
H
heptafluoroisopropyl
H
OCF3


11-2542
2,2,2-trichloroethyl
H
H
H
F
H
F
I
H
heptafluoroisopropyl
H
CF3


11-2543
2,2,2-trichloroethyl
H
H
H
F
H
F
CF3
H
heptafluoroisopropyl
H
CF3


11-2544
2,2,2-trichloroethyl
H
H
H
F
H
F
I
H
nonafluoro-2-butyl
H
I


11-2545
2,2,2-trichloroethyl
H
H
H
F
H
F
Cl
H
nonafluoro-2-butyl
H
OCF3


11-2546
2,2,2-trichloroethyl
H
H
H
F
H
F
Br
H
nonafluoro-2-butyl
H
CF3


11-2547
2,2,2-trichloroethyl
H
H
H
F
H
F
CF3
H
nonafluoro-2-butyl
H
CF3


11-2548
2,2,2-trichloroethyl
H
H
H
H
F
F
Cl
H
pentafluoroethyl
H
Cl


11-2549
2,2,2-trichloroethyl
H
H
H
H
F
F
Br
H
heptafluoroisopropyl
H
Br


11-2550
2,2,2-trichloroethyl
H
H
H
H
F
F
Br
H
heptafluoroisopropyl
H
OCF3


11-2551
2,2,2-trichloroethyl
H
H
H
H
F
F
I
H
heptafluoroisopropyl
H
CF3


11-2552
2,2,2-trichloroethyl
H
H
H
H
F
F
CF3
H
heptafluoroisopropyl
H
CF3


11-2553
2,2,2-trichloroethyl
H
H
H
H
F
F
I
H
nonafluoro-2-butyl
H
I


11-2554
2,2,2-trichloroethyl
H
H
H
H
F
F
Cl
H
nonafluoro-2-butyl
H
OCF3


11-2555
2,2,2-trichloroethyl
H
H
H
H
F
F
Br
H
nonafluoro-2-butyl
H
CF3


11-2556
2,2,2-trichloroethyl
H
H
H
H
F
F
CF3
H
nonafluoro-2-butyl
H
CF3


11-2557
2,2,2-trichloroethyl
H
H
F
F
H
F
Cl
H
pentafluoroethyl
H
Cl


11-2558
2,2,2-trichloroethyl
H
H
F
F
H
F
Br
H
heptafluoroisopropyl
H
Br


11-2559
2,2,2-trichloroethyl
H
H
F
F
H
F
Br
H
heptafluoroisopropyl
H
OCF3


11-2560
2,2,2-trichloroethyl
H
H
F
F
H
F
I
H
heptafluoroisopropyl
H
CF3


11-2561
2,2,2-trichloroethyl
H
H
F
F
H
F
CF3
H
heptafluoroisopropyl
H
CF3


11-2562
2,2,2-trichloroethyl
H
H
F
F
H
F
I
H
nonafluoro-2-butyl
H
I


11-2563
2,2,2-trichloroethyl
H
H
F
F
H
F
Cl
H
nonafluoro-2-butyl
H
OCF3


11-2564
2,2,2-trichloroethyl
H
H
F
F
H
F
Br
H
nonafluoro-2-butyl
H
CF3


11-2565
2,2,2-trichloroethyl
H
H
F
F
H
F
CF3
H
nonafluoro-2-butyl
H
CF3


11-2566
2,2,2-trichloroethyl
H
H
F
H
F
F
Cl
H
pentafluoroethyl
H
Cl


11-2567
2,2,2-trichloroethyl
H
H
F
H
F
F
Br
H
heptafluoroisopropyl
H
Br


11-2568
2,2,2-trichloroethyl
H
H
F
H
F
F
Br
H
heptafluoroisopropyl
H
OCF3


11-2569
2,2,2-trichloroethyl
H
H
F
H
F
F
I
H
heptafluoroisopropyl
H
CF3


11-2570
2,2,2-trichloroethyl
H
H
F
H
F
F
CF3
H
heptafluoroisopropyl
H
CF3


11-2571
2,2,2-trichloroethyl
H
H
F
H
F
F
I
H
nonafluoro-2-butyl
H
I


11-2572
2,2,2-trichloroethyl
H
H
F
H
F
F
Cl
H
nonafluoro-2-butyl
H
OCF3


11-2573
2,2,2-trichloroethyl
H
H
F
H
F
F
Br
H
nonafluoro-2-butyl
H
CF3


11-2574
2,2,2-trichloroethyl
H
H
F
H
F
F
CF3
H
nonafluoro-2-butyl
H
CF3


11-2575
2,2,2-trichloroethyl
H
H
H
F
F
F
Cl
H
pentafluoroethyl
H
Cl


11-2576
2,2,2-trichloroethyl
H
H
H
F
F
F
Br
H
heptafluoroisopropyl
H
Br


11-2577
2,2,2-trichloroethyl
H
H
H
F
F
F
Br
H
heptafluoroisopropyl
H
OCF3


11-2578
2,2,2-trichloroethyl
H
H
H
F
F
F
I
H
heptafluoroisopropyl
H
CF3


11-2579
2,2,2-trichloroethyl
H
H
H
F
F
F
CF3
H
heptafluoroisopropyl
H
CF3


11-2580
2,2,2-trichloroethyl
H
H
H
F
F
F
i
H
nonafluoro-2-butyl
H
I


11-2581
2,2,2-trichloroethyl
H
H
H
F
F
F
Cl
H
nonafluoro-2-butyl
H
OCF3


11-2582
2,2,2-trichloroethyl
H
H
H
F
F
F
Br
H
nonafluoro-2-butyl
H
CF3


11-2583
2,2,2-trichloroethyl
H
H
H
F
F
F
CF3
H
nonafluoro-2-butyl
H
CF3


11-2584
2,2,2-trichloroethyl
H
H
F
F
F
F
Cl
H
pentafluoroethyl
H
Cl


11-2585
2,2,2-trichloroethyl
H
H
F
F
F
F
Br
H
heptafluoroisopropyl
H
Br


11-2586
2,2,2-trichloroethyl
H
H
F
F
F
F
Br
H
heptafluoroisopropyl
H
OCF3


11-2587
2,2,2-trichloroethyl
H
H
F
F
F
F
I
H
heptafluoroisopropyl
H
CF3


11-2588
2,2,2-trichloroethyl
H
H
F
F
F
F
CF3
H
heptafluoroisopropyl
H
CF3


11-2589
2,2,2-trichloroethyl
H
H
F
F
F
F
I
H
nonafluoro-2-butyl
H
I


11-2590
2,2,2-trichloroethyl
H
H
F
F
F
F
Cl
H
nonafluoro-2-butyl
H
OCF3


11-2591
2,2,2-trichloroethyl
H
H
F
F
F
F
Br
H
nonafluoro-2-butyl
H
CF3


11-2592
2,2,2-trichloroethyl
H
H
F
F
F
F
CF3
H
nonafluoro-2-butyl
H
CF3


11-2593
2,2,2-trichloroethyl
H
H
H
CN
H
H
F
H
heptafluoroisopropyl
H
OCF3


11-2594
2,2,2-trichloroethyl
H
H
H
CN
H
H
F
H
nonafluoro-2-butyl
H
OCF3


11-2605
2,2,2-trichloroethyl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


11-2634
2,2,2-trichloroethyl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


11-2663
2,2,2-trichloroethyl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
OCF3


11-2692
2,2,2-trichloroethyl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


11-2721
2,2,2-trichloroethyl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
OCF3


11-2750
2,2,2-trichloroethyl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
OCF3


11-2769
2,2,2-trichloroethyl
H
H
H
CN
H
H
F
H
heptafluoroisopropyl
H
CF3


11-2770
2,2,2-trichloroethyl
H
H
H
CN
H
H
F
H
nonafluoro-2-butyl
H
CF3


11-2781
2,2,2-trichloroethyl
H
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


11-2810
2,2,2-trichloroethyl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


11-2839
2,2,2-trichloroethyl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


11-2852
4,4,4-trifluoro-n-butyl
H
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


11-2868
2,2,2-trichloroethyl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


11-2881
4,4,4-trifluoro-n-butyl
H
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


11-2897
2,2,2-trichloroethyl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


11-2910
4,4,4-trifluoro-n-butyl
H
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


11-2926
2,2,2-trichloroethyl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


11-2939
4,4,4-trifluoro-n-butyl
H
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


11-2955
2,2,2-trichloroethyl
H
H
H
CN
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


11-2984
2,2,2-trichloroethyl
H
H
H
CN
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


11-3013
2,2,2-trichloroethyl
H
H
H
CN
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


11-3042
2,2,2-trichloroethyl
H
H
H
CN
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


11-3071
2,2,2-trichloroethyl
H
H
H
CN
H
H
CF3
H
heptafluoroisopropyl
H
CF3


11-3100
2,2,2-trichloroethyl
H
H
H
CN
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


11-3119
2,2,2-trichloroethyl
H
H
F
CN
H
H
F
H
heptafluoroisopropyl
H
F


11-3120
2,2,2-trichloroethyl
H
H
F
CN
H
H
F
H
nonafluoro-2-butyl
H
F


11-3131
2,2,2-trichloroethyl
H
H
F
CN
H
H
Cl
H
heptafluoroisopropyl
H
Cl


11-3160
2,2,2-trichloroethyl
H
H
F
CN
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


11-3189
2,2,2-trichloroethyl
H
H
F
CN
H
H
Br
H
heptafluoroisopropyl
H
Br


11-3218
2,2,2-trichloroethyl
H
H
F
CN
H
H
Br
H
nonafluoro-2-butyl
H
Br


11-3247
2,2,2-trichloroethyl
H
H
F
CN
H
H
I
H
heptafluoroisopropyl
H
I


11-3276
2,2,2-trichloroethyl
H
H
F
CN
H
H
I
H
nonafluoro-2-butyl
H
I


11-3295
2,2,2-trichloroethyl
H
H
F
CN
H
H
F
H
heptafluoroisopropyl
H
Cl


11-3296
2,2,2-trichloroethyl
H
H
F
CN
H
H
F
H
heptafluoroisopropyl
H
Br


11-3297
2,2,2-trichloroethyl
H
H
F
CN
H
H
F
H
heptafluoroisopropyl
H
I


11-3298
2,2,2-trichloroethyl
H
H
F
CN
H
H
Cl
H
heptafluoroisopropyl
H
Br


11-3299
2,2,2-trichloroethyl
H
H
F
CN
H
H
Cl
H
heptafluoroisopropyl
H
I


11-3300
2,2,2-trichloroethyl
H
H
F
CN
H
H
Br
H
heptafluoroisopropyl
H
I


11-3301
2,2,2-trichloroethyl
H
H
F
CN
H
H
F
H
nonafluoro-2-butyl
H
Cl


11-3302
2,2,2-trichloroethyl
H
H
F
CN
H
H
F
H
nonafluoro-2-butyl
H
Br


11-3303
2,2,2-trichloroethyl
H
H
F
CN
H
H
F
H
nonafluoro-2-butyl
H
I


11-3304
2,2,2-trichloroethyl
H
H
F
CN
H
H
Cl
H
nonafluoro-2-butyl
H
Br


11-3305
2,2,2-trichloroethyl
H
H
F
CN
H
H
Cl
H
nonafluoro-2-butyl
H
I


11-3306
2,2,2-trichloroethyl
H
H
F
CN
H
H
Br
H
nonafluoro-2-butyl
H
I


11-3307
2,2,2-trichloroethyl
H
H
F
CN
H
H
F
H
heptafluoroisopropyl
H
OCF3


11-3308
2,2,2-trichloroethyl
H
H
F
CN
H
H
F
H
nonafluoro-2-butyl
H
OCF3


11-3319
2,2,2-trichloroethyl
H
H
F
CN
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


11-3348
2,2,2-trichloroethyl
H
H
F
CN
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


11-3377
2,2,2-trichloroethyl
H
H
F
CN
H
H
Br
H
heptafluoroisopropyl
H
OCF3


11-3406
2,2,2-trichloroethyl
H
H
F
CN
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


11-3435
2,2,2-trichloroethyl
H
H
F
CN
H
H
I
H
heptafluoroisopropyl
H
OCF3


11-3464
2,2,2-trichloroethyl
H
H
F
CN
H
H
I
H
nonafluoro-2-butyl
H
OCF3


11-3483
2,2,2-trichloroethyl
H
H
F
CN
H
H
F
H
heptafluoroisopropyl
H
CF3


11-3484
2,2,2-trichloroethyl
H
H
F
CN
H
H
F
H
nonafluoro-2-butyl
H
CF3


11-3495
2,2,2-trichloroethyl
H
H
F
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


11-3524
2,2,2-trichloroethyl
H
H
F
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


11-3553
2,2,2-trichloroethyl
H
H
F
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


11-3566
4,4,4-trifluoro-n-butyl
H
H
F
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


11-3582
2,2,2-trichloroethyl
H
H
F
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


11-3595
4,4,4-trifluoro-n-butyl
H
H
F
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


11-3611
2,2,2-trichloroethyl
H
H
F
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


11-3624
4,4,4-trifluoro-n-butyl
H
H
F
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


11-3640
2,2,2-trichloroethyl
H
H
F
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


11-3653
4,4,4-trifluoro-n-butyl
H
H
F
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


11-3669
2,2,2-trichloroethyl
H
H
F
CN
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


11-3698
2,2,2-tnchloroethyl
H
H
F
CN
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


11-3727
2,2,2-trichloroethyl
H
H
F
CN
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


11-3756
2,2,2-trichloroethyl
H
H
F
CN
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


11-3785
2,2,2-trichloroethyl
H
H
F
CN
H
H
CF3
H
heptafluoroisopropyl
H
CF3


11-3814
2,2,2-trichloroethyl
H
H
F
CN
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


11-3833
2,2,2-trichloroethyl
H
H
F
CN
F
H
F
H
heptafluoroisopropyl
H
F


11-3834
2,2,2-trichloroethyl
H
H
F
CN
F
H
F
H
nonafluoro-2-butyl
H
F


11-3845
2,2,2-trichloroethyl
H
H
F
CN
F
H
Cl
H
heptafluoroisopropyl
H
Cl


11-3874
2,2,2-trichloroethyl
H
H
F
CN
F
H
Cl
H
nonafluoro-2-butyl
H
Cl


11-3903
2,2,2-trichloroethyl
H
H
F
CN
F
H
Br
H
heptafluoroisopropyl
H
Br


11-3932
2,2,2-trichloroethyl
H
H
F
CN
F
H
Br
H
nonafluoro-2-butyl
H
Br


11-3961
2,2,2-trichloroethyl
H
H
F
CN
F
H
I
H
heptafluoroisopropyl
H
I


11-3990
2,2,2-trichloroethyl
H
H
F
CN
F
H
I
H
nonafluoro-2-butyl
H
I


11-4009
2,2,2-trichloroethyl
H
H
F
CN
F
H
F
H
heptafluoroisopropyl
H
Cl


11-4010
2,2,2-trichloroethyl
H
H
F
CN
F
H
F
H
heptafluoroisopropyl
H
Br


11-4011
2,2,2-trichloroethyl
H
H
F
CN
F
H
F
H
heptafluoroisopropyl
H
I


11-4012
2,2,2-trichloroethyl
H
H
F
CN
F
H
Cl
H
heptafluoroisopropyl
H
Br


11-4013
2,2,2-trichloroethyl
H
H
F
CN
F
H
Cl
H
heptafluoroisopropyl
H
I


11-4014
2,2,2-trichloroethyl
H
H
F
CN
F
H
Br
H
heptafluoroisopropyl
H
I


11-4015
2,2,2-trichloroethyl
H
H
F
CN
F
H
F
H
nonafluoro-2-butyl
H
Cl


11-4016
2,2,2-trichloroethyl
H
H
F
CN
F
H
F
H
nonafluoro-2-butyl
H
Br


11-4017
2,2,2-trichloroethyl
H
H
F
CN
F
H
F
H
nonafluoro-2-butyl
H
I


11-4018
2,2,2-trichloroethyl
H
H
F
CN
F
H
Cl
H
nonafluoro-2-butyl
H
Br


11-4019
2,2,2-trichloroethyl
H
H
F
CN
F
H
Cl
H
nonafluoro-2-butyl
H
I


11-4020
2,2,2-trichloroethyl
H
H
F
CN
F
H
Br
H
nonafluoro-2-butyl
H
I


11-4021
2,2,2-trichloroethyl
H
H
F
CN
F
H
F
H
heptafluoroisopropyl
H
OCF3


11-4022
2,2,2-trichloroethyl
H
H
F
CN
F
H
F
H
nonafluoro-2-butyl
H
OCF3


11-4033
2,2,2-trichloroethyl
H
H
F
CN
F
H
Cl
H
heptafluoroisopropyl
H
OCF3


11-4062
2,2,2-trichloroethyl
H
H
F
CN
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


11-4091
2,2,2-trichloroethyl
H
H
F
CN
F
H
Br
H
heptafluoroisopropyl
H
OCF3


11-4120
2,2,2-trichloroethyl
H
H
F
CN
F
H
Br
H
nonafluoro-2-butyl
H
OCF3


11-4149
2,2,2-trichloroethyl
H
H
F
CN
F
H
I
H
heptafluoroisopropyl
H
OCF3


11-4178
2,2,2-trichloroethyl
H
H
F
CN
F
H
I
H
nonafluoro-2-butyl
H
OCF3


11-4209
2,2,2-trichloroethyl
H
H
F
CN
F
H
Cl
H
heptafluoroisopropyl
H
CF3


11-4238
2,2,2-trichloroethyl
H
H
F
CN
F
H
Cl
H
nonafluoro-2-butyl
H
CF3


11-4267
2,2,2-trichloroethyl
H
H
F
CN
F
H
Br
H
heptafluoroisopropyl
H
CF3


11-4280
4,4,4-trifluoro-n-butyl
H
H
F
CN
F
H
Br
H
heptafluoroisopropyl
H
CF3


11-4296
2,2,2-trichloroethyl
H
H
F
CN
F
H
Br
H
nonafluoro-2-butyl
H
CF3


11-4309
4,4,4-trifluoro-n-butyl
H
H
F
CN
F
H
Br
H
nonafluoro-2-butyl
H
CF3


11-4325
2,2,2-trichloroethyl
H
H
F
CN
F
H
I
H
heptafluoroisopropyl
H
CF3


11-4338
4,4,4-trifluoro-n-butyl
H
H
F
CN
F
H
I
H
heptafluoroisopropyl
H
CF3


11-4354
2,2,2-trichloroethyl
H
H
F
CN
F
H
I
H
nonafluoro-2-butyl
H
CF3


11-4367
4,4,4-trifluoro-n-butyl
H
H
F
CN
F
H
I
H
nonafluoro-2-butyl
H
CF3


11-4383
2,2,2-trichloroethyl
H
H
F
CN
F
H
OCF3
H
heptafluoroisopropyl
H
OCF3


11-4412
2,2,2-trichloroethyl
H
H
F
CN
F
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


11-4441
2,2,2-trichloroethyl
H
H
F
CN
F
H
CF3
H
heptafluoroisopropyl
H
OCF3


11-4470
2,2,2-trichloroethyl
H
H
F
CN
F
H
CF3
H
nonafluoro-2-butyl
H
OCF3


11-4499
2,2,2-trichloroethyl
H
H
F
CN
F
H
CF3
H
heptafluoroisopropyl
H
CF3


11-4528
2,2,2-trichloroethyl
H
H
F
CN
F
H
CF3
H
nonafluoro-2-butyl
H
CF3











embedded image





















TABLE 12





compound














number
Q2
R1
R2
X1
X2
X3
X4
Y1
Y2
Y3
Y4
Y5







12-1
2,2,2-trichloroethyl
Me
H
H
H
H
H
F
H
heptafluoroisopropyl
H
OCF3


12-2
2,2,2-trichloroethyl
Me
H
H
H
H
H
F
H
nonafluoro-2-butyl
H
OCF3


12-13
2,2,2-trichloroethyl
Me
H
H
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


12-42
2,2,2-trichloroethyl
Me
H
H
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


12-71
2,2,2-trichloroethyl
Me
H
H
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


12-100
2,2,2-trichloroethyl
Me
H
H
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


12-129
2,2,2-trichloroethyl
Me
H
H
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


12-158
2,2,2-trichloroethyl
Me
H
H
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


12-177
2,2,2-trichloroethyl
Me
H
H
H
H
H
F
H
heptafluoroisopropyl
H
CF3


12-178
2,2,2-trichloroethyl
Me
H
H
H
H
H
F
H
nonafluoro-2-butyl
H
CF3


12-189
2,2,2-trichloroethyl
Me
H
H
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


12-218
2,2,2-trichloroethyl
Me
H
H
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


12-247
2,2,2-trichloroethyl
Me
H
H
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


12-276
2,2,2-trichloroethyl
Me
H
H
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


12-305
2,2,2-trichloroethyl
Me
H
H
H
H
H
I
H
heptafluoroisopropyl
H
CF3


12-334
2,2,2-trichloroethyl
Me
H
H
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


12-363
2,2,2-trichloroethyl
Me
H
H
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


12-392
2,2,2-trichloroethyl
Me
H
H
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


12-421
2,2,2-trichloroethyl
Me
H
H
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


12-450
2,2,2-trichloroethyl
Me
H
H
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


12-479
2,2,2-trichloroethyl
Me
H
H
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


12-508
2,2,2-trichloroethyl
Me
H
H
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


12-527
2,2,2-trichloroethyl
Me
H
F
H
H
H
F
H
heptafluoroisopropyl
H
F


12-528
2,2,2-trichloroethyl
Me
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


12-529
2,2,2-trichloroethyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
Br


12-530
2,2,2-trichloroethyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
I


12-531
2,2,2-trichloroethyl
Me
H
F
H
H
H
F
H
heptafluoroisopropyl
H
OCF3


12-532
2,2,2-trichloroethyl
Me
H
F
H
H
H
F
H
nonafluoro-2-butyl
H
OCF3


12-543
2,2,2-trichloroethyl
Me
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


12-572
2,2,2-trichloroethyl
Me
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


12-601
2,2,2-trichloroethyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


12-630
2,2,2-trichloroethyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


12-659
2,2,2-trichloroethyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


12-688
2,2,2-trichloroethyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


12-707
2,2,2-trichloroethyl
Me
H
F
H
H
H
F
H
heptafluoroisopropyl
H
CF3


12-708
2,2,2-trichloroethyl
Me
H
F
H
H
H
F
H
nonafluoro-2-butyl
H
CF3


12-715
2-cyanoethyl
Et
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
C2F5


12-719
2,2,2-trichloroethyl
Me
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


12-721
n-propyl
Me
H
F
H
H
H
Cl
H
pentafluoroethyl
H
CF3


12-725
i-propyl
n-Pr
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


12-728
1,3-dichloro-2-propyl
Me
H
F
H
H
H
Cl
H
pentafluoroethyl
H
CF3


12-729
1-chloro-3-fluoro-2-propyl
i-Pr
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


12-733
i-butyl
CH2CH═CH2
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


12-739
ethyl
Me
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


12-744
2-cyanoethyl
CN
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


12-748
2,2,2-trichloroethyl
Me
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


12-750
n-propyl
CH2C≡CH
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


12-762
i-butyl
NH2
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


12-767
methyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


12-768
ethyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


12-769
2-fluoroethyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


12-770
2-chloroethyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


12-771
2-bromoethyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


12-772
2-iodoethyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


12-773
2-cyanoethyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
C2F5


12-774
2,2-difluoroethyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


12-775
2,2-dichloroethyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


12-776
2,2,2-trifluoroethyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


12-777
2,2,2-trichloroethyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


12-778
2,2,2-tribromoethyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


12-779
n-propyl
C(O)OMe
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


12-780
3-fluoro-n-propyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


12-781
3-chloro-n-propyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


12-782
3-bromo-n-propyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


12-783
i-propyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


12-784
1,2-difluoro-2-propyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
n-C3F7


12-785
1,3-difluoro-2-propyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


12-786
1,3-dichloro-2-propyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


12-787
1-chloro-3-fluoro-2-propyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


12-788
3,3,3-trifluoro-n-propyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


12-789
n-butyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


12-790
4,4,4-trifluoro-n-butyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


12-791
i-butyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


12-792
s-butyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


12-793
vinyl
C(O)C(O)OMe
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


12-794
benzyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


12-795
phenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


12-796
methyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


12-797
ethyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


12-798
2-fluoroethyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


12-799
2-chloroethyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


12-800
2-bromoethyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


12-801
2-iodoethyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
GF3


12-802
2-cyanoethyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


12-803
2,2-difluoroethyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


12-804
2,2-dichloroethyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


12-805
2,2,2-trifluoroethyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


12-806
2,2,2-trichloroethyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


12-807
2,2,2-tribromoethyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


12-808
n-propyl
C(O)OEt
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


12-809
3-fluoro-n-propyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


12-810
3-chloro-n-propyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


12-811
3-bromo-n-propyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


12-812
i-propyl
C(O)Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


12-813
1,2-difluoro-2-propyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


12-814
1,3-difluoro-2-propyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


12-815
1,3-dichloro-2-propyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


12-816
1-chloro-3-fluoro-2-propyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


12-817
3,3,3-trifluoro-n-propyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


12-818
n-butyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


12-819
4,4,4-trifluoro-n-butyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


12-820
i-butyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


12-821
s-butyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


12-822
vinyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


12-823
benzyl
Me
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


12-824
phenyl
C(O)C(O)OEt
H
F
H
H
H
Br
H
nonafluoro-2-butyl
H
i-C3F7


12-825
methyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


12-826
ethyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


12-827
2-fluoroethyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


12-828
2-chloroethyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


12-829
2-bromoethyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


12-830
2-iodoethyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


12-831
2-cyanoethyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


12-832
2,2-difluoroethyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


12-833
2,2-dichloroethyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


12-834
2,2,2-trifluoroethyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


12-835
2,2,2-trichloroethyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


12-836
2,2,2-tribromoethyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


12-837
n-propyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


12-838
3-fluoro-n-propyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


12-839
3-chloro-n-propyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


12-840
3-bromo-n-propyl
C(O)Et
H
F
H
H
H
I
H
heptafluoroisopropyl
H
C2F5


12-841
i-propyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


12-842
1,2-difluoro-2-propyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


12-843
1,3-difluoro-2-propyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


12-844
1,3-dichloro-2-propyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


12-845
1-chloro-3-fluoro-2-propyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


12-846
3,3,3-trifluoro-n-propyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


12-847
n-butyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


12-848
4,4,4-trifluoro-n-butyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


12-849
i-butyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


12-850
s-butyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


12-851
vinyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


12-852
benzyl
S(O)2Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


12-853
phenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


12-854
methyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


12-855
ethyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


12-856
2-fluoroethyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


12-857
2-chloroethyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


12-858
2-bromoethyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


12-859
2-iodoethyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


12-860
2-cyanoethyl
S(O)2Et
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


12-861
2,2-difluoroethyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


12-862
2,2-dichloroethyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


12-863
2,2,2-trifluoroethyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


12-864
2,2,2-trichloroethyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


12-865
2,2,2-tribromoethyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


12-866
n-propyl
CH2Ph
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
n-C3F7


12-867
3-fluoro-n-propyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


12-868
3-chloro-n-propyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


12-869
3-bromo-n-propyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


12-870
i-propyl
CH2(3-Py)
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


12-871
1,2-difluoro-2-propyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


12-872
1,3-difluoro-2-propyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


12-873
1,3-dichloro-2-propyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


12-874
1-chloro-3-fluoro-2-propyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


12-875
3,3,3-trifluoro-n-propyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


12-876
n-butyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


12-877
4,4,4-trifluoro-n-butyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


12-878
i-butyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


12-879
s-butyl
CH2(3-Py—N-
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3




oxide)


12-880
vinyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
i-C3F7


12-881
benzyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


12-882
phenyl
Me
H
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


12-893
2,2,2-trichloroethyl
Me
H
F
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


12-922
2,2,2-trichloroethyl
Me
H
F
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


12-951
2,2,2-trichloroethyl
Me
H
F
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


12-980
2,2,2-trichloroethyl
Me
H
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


12-1009
2,2,2-trichloroethyl
Me
H
F
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


12-1038
2,2,2-trichloroethyl
Me
H
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


12-1057
2,2,2-trichloroethyl
Me
H
H
F
H
H
F
H
heptafluoroisopropyl
H
F


12-1058
2,2,2-trichloroethyl
Me
H
H
F
H
H
F
H
nonafluoro-2-butyl
H
F


12-1069
2,2,2-trichloroethyl
Me
H
H
F
H
H
Cl
H
heptafluoroisopropyl
H
Cl


12-1098
2,2,2-trichloroethyl
Me
H
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


12-1127
2,2,2-trichloroethyl
Me
H
H
F
H
H
Br
H
heptafluoroisopropyl
H
Br


12-1156
2,2,2-trichloroethyl
Me
H
H
F
H
H
Br
H
nonafluoro-2-butyl
H
Br


12-1185
2,2,2-trichloroethyl
Me
H
H
F
H
H
I
H
heptafluoroisopropyl
H
I


12-1214
2,2,2-trichloroethyl
Me
H
H
F
H
H
I
H
nonafluoro-2-butyl
H
I


12-1236
2,2,2-trichloroethyl
Me
H
H
F
H
H
Cl
H
heptafluoroisopropyl
H
Br


12-1245
2,2,2-trichloroethyl
Me
H
H
F
H
H
F
H
heptafluoroisopropyl
H
OCF3


12-1246
2,2,2-trichloroethyl
Me
H
H
F
H
H
F
H
nonafluoro-2-butyl
H
OCF3


12-1257
2,2,2-trichloroethyl
Me
H
H
F
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


12-1286
2,2,2-trichloroethyl
Me
H
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


12-1315
2,2,2-trichloroethyl
Me
H
H
F
H
H
Br
H
heptafluoroisopropyl
H
OCF3


12-1344
2,2,2-trichloroethyl
Me
H
H
F
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


12-1373
2,2,2-trichloroethyl
Me
H
H
F
H
H
I
H
heptafluoroisopropyl
H
OCF3


12-1402
2,2,2-trichloroethyl
Me
H
H
F
H
H
I
H
nonafluoro-2-butyl
H
OCF3


12-1421
2,2,2-trichloroethyl
Me
H
H
F
H
H
F
H
heptafluoroisopropyl
H
CF3


12-1422
2,2,2-trichloroethyl
Me
H
H
F
H
H
F
H
nonafluoro-2-butyl
H
CF3


12-1433
2,2,2-trichloroethyl
Me
H
H
F
H
H
Cl
H
heptafluoroisopropyl
H
CF3


12-1462
2,2,2-trichloroethyl
Me
H
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


12-1491
2,2,2-trichloroethyl
Me
H
H
F
H
H
Br
H
heptafluoroisopropyl
H
CF3


12-1520
2,2,2-trichloroethyl
Me
H
H
F
H
H
Br
H
nonafluoro-2-butyl
H
CF3


12-1549
2,2,2-trichloroethyl
Me
H
H
F
H
H
I
H
heptafluoroisopropyl
H
CF3


12-1578
2,2,2-trichloroethyl
Me
H
H
F
H
H
I
H
nonafluoro-2-butyl
H
CF3


12-1607
2,2,2-trichloroethyl
Me
H
H
F
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


12-1636
2,2,2-trichloroethyl
Me
H
H
F
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


12-1665
2,2,2-trichloroethyl
Me
H
H
F
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


12-1694
2,2,2-trichloroethyl
Me
H
H
F
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


12-1723
2,2,2-trichloroethyl
Me
H
H
F
H
H
CF3
H
heptafluoroisopropyl
H
CF3


12-1752
2,2,2-trichloroethyl
Me
H
H
F
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


12-1771
2,2,2-trichloroethyl
Me
H
F
F
H
H
F
H
heptafluoroisopropyl
H
F


12-1772
2,2,2-trichloroethyl
Me
H
F
F
H
H
F
H
nonafluoro-2-butyl
H
F


12-1783
2,2,2-trichloroethyl
Me
H
F
F
H
H
Cl
H
heptafluoroisopropyl
H
Cl


12-1812
2,2,2-trichloroethyl
Me
H
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


12-1841
2,2,2-trichloroethyl
Me
H
F
F
H
H
Br
H
heptafluoroisopropyl
H
Br


12-1870
2,2,2-trichloroethyl
Me
H
F
F
H
H
Br
H
nonafluoro-2-butyl
H
Br


12-1899
2,2,2-trichloroethyl
Me
H
F
F
H
H
I
H
heptafluoroisopropyl
H
I


12-1928
2,2,2-trichloroethyl
Me
H
F
F
H
H
I
H
nonafluoro-2-butyl
H
I


12-1956
2,2,2-trichloroethyl
Me
H
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
Br


12-1959
2,2,2-trichloroethyl
Me
H
F
F
H
H
F
H
heptafluoroisopropyl
H
OCF3


12-1960
2,2,2-trichloroethyl
Me
H
F
F
H
H
F
H
nonafluoro-2-butyl
H
OCF3


12-1971
2,2,2-trichloroethyl
Me
H
F
F
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


12-2000
2,2,2-trichloroethyl
Me
H
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


12-2029
2,2,2-trichloroethyl
Me
H
F
F
H
H
Br
H
heptafluoroisopropyl
H
OCF3


12-2058
2,2,2-trichloroethyl
Me
H
F
F
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


12-2087
2,2,2-trichloroethyl
Me
H
F
F
H
H
I
H
heptafluoroisopropyl
H
OCF3


12-2116
2,2,2-trichloroethyl
Me
H
F
F
H
H
I
H
nonafluoro-2-butyl
H
OCF3


12-2135
2,2,2-trichloroethyl
Me
H
F
F
H
H
F
H
heptafluoroisopropyl
H
CF3


12-2136
2,2,2-trichloroethyl
Me
H
F
F
H
H
F
H
nonafluoro-2-butyl
H
CF3


12-2147
2,2,2-trichloroethyl
Me
H
F
F
H
H
Cl
H
heptafluoroisopropyl
H
CF3


12-2176
2,2,2-trichloroethyl
Me
H
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


12-2205
2,2,2-trichloroethyl
Me
H
F
F
H
H
Br
H
heptafluoroisopropyl
H
CF3


12-2234
2,2,2-trichloroethyl
Me
H
F
F
H
H
Br
H
nonafluoro-2-butyl
H
CF3


12-2263
2,2,2-trichloroethyl
Me
H
F
F
H
H
I
H
heptafluoroisopropyl
H
CF3


12-2292
2,2,2-trichloroethyl
Me
H
F
F
H
H
I
H
nonafluoro-2-butyl
H
CF3


12-2321
2,2,2-trichloroethyl
Me
H
F
F
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


12-2350
2,2,2-trichloroethyl
Me
H
F
F
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


12-2379
2,2,2-trichloroethyl
Me
H
F
F
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


12-2408
2,2,2-trichloroethyl
Me
H
F
F
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


12-2437
2,2,2-trichloroethyl
Me
H
F
F
H
H
CF3
H
heptafluoroisopropyl
H
CF3


12-2466
2,2,2-trichloroethyl
Me
H
F
F
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


12-2485
2,2,2-trichloroethyl
Me
H
F
F
F
H
Cl
H
pentafluoroethyl
H
Cl


12-2486
2,2,2-trichloroethyl
Me
H
F
F
F
H
Br
H
heptafluoroisopropyl
H
Br


12-2487
2,2,2-trichloroethyl
Me
H
F
F
F
H
Br
H
heptafluoroisopropyl
H
OCF3


12-2488
2,2,2-trichloroethyl
Me
H
F
F
F
H
I
H
heptafluoroisopropyl
H
CF3


12-2489
2,2,2-trichloroethyl
Me
H
F
F
F
H
CF3
H
heptafluoroisopropyl
H
CF3


12-2490
2,2,2-trichloroethyl
Me
H
F
F
F
H
I
H
nonafluoro-2-butyl
H
I


12-2491
2,2,2-trichloroethyl
Me
H
F
F
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


12-2492
2,2,2-trichloroethyl
Me
H
F
F
F
H
Br
H
nonafluoro-2-butyl
H
CF3


12-2493
2,2,2-trichloroethyl
Me
H
F
F
F
H
CF3
H
nonafluoro-2-butyl
H
CF3


12-2494
2,2,2-trichloroethyl
Me
H
H
H
F
H
Cl
H
pentafluoroethyl
H
Cl


12-2495
2,2,2-trichloroethyl
Me
H
H
H
F
H
Br
H
heptafluoroisopropyl
H
Br


12-2496
2,2,2-trichloroethyl
Me
H
H
H
F
H
Br
H
heptafluoroisopropyl
H
OCF3


12-2497
2,2,2-trichloroethyl
Me
H
H
H
F
H
I
H
heptafluoroisopropyl
H
CF3


12-2498
2,2,2-trichloroethyl
Me
H
H
H
F
H
CF3
H
heptafluoroisopropyl
H
CF3


12-2499
2,2,2-trichloroethyl
Me
H
H
H
F
H
I
H
nonafluoro-2-butyl
H
I


12-2500
2,2,2-trichloroethyl
Me
H
H
H
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


12-2501
2,2,2-trichloroethyl
Me
H
H
H
F
H
Br
H
nonafluoro-2-butyl
H
CF3


12-2502
2,2,2-trichloroethyl
Me
H
H
H
F
H
CF3
H
nonafluoro-2-butyl
H
CF3


12-2503
2,2,2-trichloroethyl
Me
H
H
H
H
F
Cl
H
pentafluoroethyl
H
Cl


12-2504
2,2,2-trichloroethyl
Me
H
H
H
H
F
Br
H
heptafluoroisopropyl
H
Br


12-2505
2,2,2-trichloroethyl
Me
H
H
H
H
F
Br
H
heptafluoroisopropyl
H
OCF3


12-2506
2,2,2-trichloroethyl
Me
H
H
H
H
F
I
H
heptafluoroisopropyl
H
CF3


12-2507
2,2,2-trichloroethyl
Me
H
H
H
H
F
CF3
H
heptafluoroisopropyl
H
CF3


12-2508
2,2,2-trichloroethyl
Me
H
H
H
H
F
I
H
nonafluoro-2-butyl
H
I


12-2509
2,2,2-trichloroethyl
Me
H
H
H
H
F
Cl
H
nonafluoro-2-butyl
H
OCF3


12-2510
2,2,2-trichloroethyl
Me
H
H
H
H
F
Br
H
nonafluoro-2-butyl
H
CF3


12-2511
2,2,2-trichloroethyl
Me
H
H
H
H
F
CF3
H
nonafluoro-2-butyl
H
CF3


12-2512
2,2,2-trichloroethyl
Me
H
F
H
F
H
Cl
H
pentafluoroethyl
H
Cl


12-2513
2,2,2-trichloroethyl
Me
H
F
H
F
H
Br
H
heptafluoroisopropyl
H
Br


12-2514
2,2,2-trichloroethyl
Me
H
F
H
F
H
Br
H
heptafluoroisopropyl
H
OCF3


12-2515
2,2,2-trichloroethyl
Me
H
F
H
F
H
I
H
heptafluoroisopropyl
H
CF3


12-2516
2,2,2-trichloroethyl
Me
H
F
H
F
H
CF3
H
heptafluoroisopropyl
H
CF3


12-2517
2,2,2-trichloroethyl
Me
H
F
H
F
H
I
H
nonafluoro-2-butyl
H
I


12-2518
2,2,2-trichloroethyl
Me
H
F
H
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


12-2519
2,2,2-trichloroethyl
Me
H
F
H
F
H
Br
H
nonafluoro-2-butyl
H
CF3


12-2520
2,2,2-trichloroethyl
Me
H
F
H
F
H
CF3
H
nonafluoro-2-butyl
H
CF3


12-2521
2,2,2-trichloroethyl
Me
H
F
H
H
F
Cl
H
pentafluoroethyl
H
Cl


12-2522
2,2,2-trichloroethyl
Me
H
F
H
H
F
Br
H
heptafluoroisopropyl
H
Br


12-2523
2,2,2-trichloroethyl
Me
H
F
H
H
F
Br
H
heptafluoroisopropyl
H
OCF3


12-2524
2,2,2-trichloroethyl
Me
H
F
H
H
F
I
H
heptafluoroisopropyl
H
CF3


12-2525
2,2,2-trichloroethyl
Me
H
F
H
H
F
CF3
H
heptafluoroisopropyl
H
CF3


12-2526
2,2,2-trichloroethyl
Me
H
F
H
H
F
I
H
nonafluoro-2-butyl
H
I


12-2527
2,2,2-trichloroethyl
Me
H
F
H
H
F
Cl
H
nonafluoro-2-butyl
H
OCF3


12-2528
2,2,2-trichloroethyl
Me
H
F
H
H
F
Br
H
nonafluoro-2-butyl
H
CF3


12-2529
2,2,2-trichloroethyl
Me
H
F
H
H
F
CF3
H
nonafluoro-2-butyl
H
CF3


12-2530
2,2,2-trichloroethyl
Me
H
H
F
F
H
Cl
H
pentafluoroethyl
H
Cl


12-2531
2,2,2-trichloroethyl
Me
H
H
F
F
H
Br
H
heptafluoroisopropyl
H
Br


12-2532
2,2,2-trichloroethyl
Me
H
H
F
F
H
Br
H
heptafluoroisopropyl
H
OCF3


12-2533
2,2,2-trichloroethyl
Me
H
H
F
F
H
I
H
heptafluoroisopropyl
H
CF3


12-2534
2,2,2-trichloroethyl
Me
H
H
F
F
H
CF3
H
heptafluoroisopropyl
H
CF3


12-2535
2,2,2-trichloroethyl
Me
H
H
F
F
H
I
H
nonafluoro-2-butyl
H
I


12-2536
2,2,2-trichloroethyl
Me
H
H
F
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


12-2537
2,2,2-trichloroethyl
Me
H
H
F
F
H
Br
H
nonafluoro-2-butyl
H
CF3


12-2538
2,2,2-trichloroethyl
Me
H
H
F
F
H
CF3
H
nonafluoro-2-butyl
H
CF3


12-2539
2,2,2-trichloroethyl
Me
H
H
F
H
F
Cl
H
pentafluoroethyl
H
Cl


12-2540
2,2,2-trichloroethyl
Me
H
H
F
H
F
Br
H
heptafluoroisopropyl
H
Br


12-2541
2,2,2-trichloroethyl
Me
H
H
F
H
F
Br
H
heptafluoroisopropyl
H
OCF3


12-2542
2,2,2-trichloroethyl
Me
H
H
F
H
F
I
H
heptafluoroisopropyl
H
CF3


12-2543
2,2,2-trichloroethyl
Me
H
H
F
H
F
CF3
H
heptafluoroisopropyl
H
CF3


12-2544
2,2,2-trichloroethyl
Me
H
H
F
H
F
I
H
nonafluoro-2-butyl
H
I


12-2545
2,2,2-trichloroethyl
Me
H
H
F
H
F
Cl
H
nonafluoro-2-butyl
H
OCF3


12-2546
2,2,2-trichloroethyl
Me
H
H
F
H
F
Br
H
nonafluoro-2-butyl
H
CF3


12-2547
2,2,2-trichloroethyl
Me
H
H
F
H
F
CF3
H
nonafluoro-2-butyl
H
CF3


12-2548
2,2,2-trichloroethyl
Me
H
H
H
F
F
Cl
H
pentafluoroethyl
H
Cl


12-2549
2,2,2-trichloroethyl
Me
H
H
H
F
F
Br
H
heptafluoroisopropyl
H
Br


12-2550
2,2,2-trichloroethyl
Me
H
H
H
F
F
Br
H
heptafluoroisopropyl
H
OCF3


12-2551
2,2,2-trichloroethyl
Me
H
H
H
F
F
I
H
heptafluoroisopropyl
H
CF3


12-2552
2,2,2-trichloroethyl
Me
H
H
H
F
F
CF3
H
heptafluoroisopropyl
H
CF3


12-2553
2,2,2-trichloroethyl
Me
H
H
H
F
F
I
H
nonafluoro-2-butyl
H
I


12-2554
2,2,2-trichloroethyl
Me
H
H
H
F
F
Cl
H
nonafluoro-2-butyl
H
OCF3


12-2555
2,2,2-trichloroethyl
Me
H
H
H
F
F
Br
H
nonafluoro-2-butyl
H
CF3


12-2556
2,2,2-trichloroethyl
Me
H
H
H
F
F
CF3
H
nonafluoro-2-butyl
H
CF3


12-2557
2,2,2-trichloroethyl
Me
H
F
F
H
F
Cl
H
pentafluoroethyl
H
Cl


12-2558
2,2,2-trichloroethyl
Me
H
F
F
H
F
Br
H
heptafluoroisopropyl
H
Br


12-2559
2,2,2-trichloroethyl
Me
H
F
F
H
F
Br
H
heptafluoroisopropyl
H
OCF3


12-2560
2,2,2-trichloroethyl
Me
H
F
F
H
F
I
H
heptafluoroisopropyl
H
CF3


12-2561
2,2,2-trichloroethyl
Me
H
F
F
H
F
CF3
H
heptafluoroisopropyl
H
CF3


12-2562
2,2,2-trichloroethyl
Me
H
F
F
H
F
I
H
nonafluoro-2-butyl
H
I


12-2563
2,2,2-trichloroethyl
Me
H
F
F
H
F
Cl
H
nonafluoro-2-butyl
H
OCF3


12-2564
2,2,2-trichloroethyl
Me
H
F
F
H
F
Br
H
nonafluoro-2-butyl
H
CF3


12-2565
2,2,2-trichloroethyl
Me
H
F
F
H
F
CF3
H
nonafluoro-2-butyl
H
CF3


12-2566
2,2,2-trichloroethyl
Me
H
F
H
F
F
Cl
H
pentafluoroethyl
H
Cl


12-2567
2,2,2-trichloroethyl
Me
H
F
H
F
F
Br
H
heptafluoroisopropyl
H
Br


12-2568
2,2,2-trichloroethyl
Me
H
F
H
F
F
Br
H
heptafluoroisopropyl
H
OCF3


12-2569
2,2,2-trichloroethyl
Me
H
F
H
F
F
I
H
heptafluoroisopropyl
H
CF3


12-2570
2,2,2-trichloroethyl
Me
H
F
H
F
F
CF3
H
heptafluoroisopropyl
H
CF3


12-2571
2,2,2-trichloroethyl
Me
H
F
H
F
F
I
H
nonafluoro-2-butyl
H
I


12-2572
2,2,2-trichloroethyl
Me
H
F
H
F
F
Cl
H
nonafluoro-2-butyl
H
OCF3


12-2573
2,2,2-trichloroethyl
Me
H
F
H
F
F
Br
H
nonafluoro-2-butyl
H
CF3


12-2574
2,2,2-trichloroethyl
Me
H
F
H
F
F
CF3
H
nonafluoro-2-butyl
H
CF3


12-2575
2,2,2-trichloroethyl
Me
H
H
F
F
F
Cl
H
pentafluoroethyl
H
Cl


12-2576
2,2,2-trichloroethyl
Me
H
H
F
F
F
Br
H
heptafluoroisopropyl
H
Br


12-2577
2,2,2-trichloroethyl
Me
H
H
F
F
F
Br
H
heptafluoroisopropyl
H
OCF3


12-2578
2,2,2-trichloroethyl
Me
H
H
F
F
F
I
H
heptafluoroisopropyl
H
CF3


12-2579
2,2,2-trichloroethyl
Me
H
H
F
F
F
CF3
H
heptafluoroisopropyl
H
CF3


12-2580
2,2,2-trichloroethyl
Me
H
H
F
F
F
I
H
nonafluoro-2-butyl
H
I


12-2581
2,2,2-trichloroethyl
Me
H
H
F
F
F
Cl
H
nonafluoro-2-butyl
H
OCF3


12-2582
2,2,2-trichloroethyl
Me
H
H
F
F
F
Br
H
nonafluoro-2-butyl
H
CF3


12-2583
2,2,2-trichloroethyl
Me
H
H
F
F
F
CF3
H
nonafluoro-2-butyl
H
CF3


12-2584
2,2,2-trichloroethYl
Me
H
F
F
F
F
Cl
H
pentafluoroethyl
H
Cl


12-2585
2,2,2-trichloroethyl
Me
H
F
F
F
F
Br
H
heptafluoroisopropyl
H
Br


12-2586
2,2,2-trichloroethyl
Me
H
F
F
F
F
Br
H
heptafluoroisopropyl
H
OCF3


12-2587
2,2,2-trichloroethyl
Me
H
F
F
F
F
I
H
heptafluoroisopropyl
H
CF3


12-2588
2,2,2-trichloroethyl
Me
H
F
F
F
F
CF3
H
heptafluoroisopropyl
H
CF3


12-2589
2,2,2-trichloroethyl
Me
H
F
F
F
F
I
H
nonafluoro-2-butyl
H
I


12-2590
2,2,2-trichloroethyl
Me
H
F
F
F
F
Cl
H
nonafluoro-2-butyl
H
OCF3


12-2591
2,2,2-trichloroethyl
Me
H
F
F
F
F
Br
H
nonafluoro-2-butyl
H
CF3


12-2592
2,2,2-trichloroethyl
Me
H
F
F
F
F
CF3
H
nonafluoro-2-butyl
H
CF3


12-2593
2,2,2-trichloroethyl
Me
H
H
CN
H
H
F
H
heptafluoroisopropyl
H
OCF3


12-2594
2,2,2-trichloroethyl
Me
H
H
CN
H
H
F
H
nonafluoro-2-butyl
H
OCF3


12-2605
2,2,2-trichloroethyl
Me
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


12-2634
2,2,2-trichloroethyl
Me
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


12-2663
2,2,2-trichloroethyl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
OCF3


12-2692
2,2,2-trichloroethyl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


12-2721
2,2,2-trichloroethyl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
OCF3


12-2750
2,2,2-trichloroethyl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
OCF3


12-2769
2,2,2-trichloroethyl
Me
H
H
CN
H
H
F
H
heptafluoroisopropyl
H
CF3


12-2770
2,2,2-trichloroethyl
Me
H
H
CN
H
H
F
H
nonafluoro-2-butyl
H
CF3


12-2781
2,2,2-trichloroethyl
Me
H
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


12-2810
2,2,2-trichloroethyl
Me
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


12-2839
2,2,2-trichloroethyl
Me
H
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


12-2868
2,2,2-trichloroethyl
Me
H
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


12-2897
2,2,2-trichloroethyl
Me
H
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


12-2926
2,2,2-trichloroethyl
Me
H
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


12-2955
2,2,2-trichloroethyl
Me
H
H
CN
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


12-2984
2,2,2-trichloroethyl
Me
H
H
CN
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


12-3013
2,2,2-trichloroethyl
Me
H
H
CN
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


12-3042
2,2,2-trichloroethyl
Me
H
H
CN
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


12-3071
2,2,2-trichloroethyl
Me
H
H
CN
H
H
CF3
H
heptafluoroisopropyl
H
CF3


12-3100
2,2,2-trichloroethyl
Me
H
H
CN
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


12-3119
2,2,2-trichloroethyl
Me
H
F
CN
H
H
F
H
heptafluoroisopropyl
H
F


12-3120
2,2,2-trichloroethyl
Me
H
F
CN
H
H
F
H
nonafluoro-2-butyl
H
F


12-3131
2,2,2-trichloroethyl
Me
H
F
CN
H
H
Cl
H
heptafluoroisopropyl
H
Cl


12-3160
2,2,2-trichloroethyl
Me
H
F
CN
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


12-3189
2,2,2-trichloroethyl
Me
H
F
CN
H
H
Br
H
heptafluoroisopropyl
H
Br


12-3218
2,2,2-trichloroethyl
Me
H
F
CN
H
H
Br
H
nonafluoro-2-butyl
H
Br


12-3247
2,2,2-trichloroethyl
Me
H
F
CN
H
H
I
H
heptafluoroisopropyl
H
I


12-3276
2,2,2-trichloroethyl
Me
H
F
CN
H
H
I
H
nonafluoro-2-butyl
H
I


12-3298
2,2,2-trichloroethyl
Me
H
F
CN
H
H
Cl
H
heptafluoroisopropyl
H
Br


12-3307
2,2,2-trichloroethyl
Me
H
F
CN
H
H
F
H
heptafluoroisopropyl
H
OCF3


12-3308
2,2,2-trichloroethyl
Me
H
F
CN
H
H
F
H
nonafluoro-2-butyl
H
OCF3


12-3319
2,2,2-trichloroethyl
Me
H
F
CN
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


12-3348
2,2,2-trichloroethyl
Me
H
F
CN
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


12-3377
2,2,2-trichloroethyl
Me
H
F
CN
H
H
Br
H
heptafluoroisopropyl
H
OCF3


12-3406
2,2,2-trichloroethyl
Me
H
F
CN
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


12-3435
2,2,2-trichloroethyl
Me
H
F
CN
H
H
I
H
heptafluoroisopropyl
H
OCF3


12-3464
2,2,2-trichloroethyl
Me
H
F
CN
H
H
I
H
nonafluoro-2-butyl
H
OCF3


12-3483
2,2,2-trichloroethyl
Me
H
F
CN
H
H
F
H
heptafluoroisopropyl
H
CF3


12-3484
2,2,2-trichloroethyl
Me
H
F
CN
H
H
F
H
nonafluoro-2-butyl
H
CF3


12-3495
2,2,2-trichloroethyl
Me
H
F
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


12-3524
2,2,2-trichloroethyl
Me
H
F
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


12-3553
2,2,2-trichloroethyl
Me
H
F
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


12-3582
2,2,2-trichloroethyl
Me
H
F
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


12-3611
2,2,2-trichloroethyl
Me
H
F
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


12-3640
2,2,2-trichloroethyl
Me
H
F
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


12-3669
2,2,2-trichloroethyl
Me
H
F
CN
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


12-3698
2,2,2-trichloroethyl
Me
H
F
CN
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


12-3727
2,2,2-trichloroethyl
Me
H
F
CN
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


12-3756
2,2,2-trichloroethyl
Me
H
F
CN
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


12-3785
2,2,2-trichloroethyl
Me
H
F
CN
H
H
CF3
H
heptafluoroisopropyl
H
CF3


12-3814
2,2,2-trichloroethyl
Me
H
F
CN
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


12-3833
2,2,2-trichloroethyl
Me
H
F
CN
F
H
F
H
heptafluoroisopropyl
H
F


12-3834
2,2,2-trichloroethyl
Me
H
F
CN
F
H
F
H
nonafluoro-2-butyl
H
F


12-3845
2,2,2-trichloroethyl
Me
H
F
CN
F
H
Cl
H
heptafluoroisopropyl
H
Cl


12-3874
2,2,2-trichloroethyl
Me
H
F
CN
F
H
Cl
H
nonafluoro-2-butyl
H
Cl


12-3903
2,2,2-trichloroethyl
Me
H
F
CN
F
H
Br
H
heptafluoroisopropyl
H
Br


12-3932
2,2,2-trichloroethyl
Me
H
F
CN
F
H
Br
H
nonafluoro-2-butyl
H
Br


12-3961
2,2,2-trichloroethyl
Me
H
F
CN
F
H
I
H
heptafluoroisopropyl
H
I


12-3990
2,2,2-trichloroethyl
Me
H
F
CN
F
H
I
H
nonafluoro-2-butyl
H
I


12-4018
2,2,2-trichloroethyl
Me
H
F
CN
F
H
Cl
H
nonafluoro-2-butyl
H
Br


12-4021
2,2,2-trichloroethyl
Me
H
F
CN
F
H
F
H
heptafluoroisopropyl
H
OCF3


12-4022
2,2,2-trichloroethyl
Me
H
F
CN
F
H
F
H
nonafluoro-2-butyl
H
OCF3


12-4033
2,2,2-trichloroethyl
Me
H
F
CN
F
H
Cl
H
heptafluoroisopropyl
H
OCF3


12-4062
2,2,2-trichloroethyl
Me
H
F
CN
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


12-4091
2,2,2-trichloroethyl
Me
H
F
CN
F
H
Br
H
heptafluoroisopropyl
H
OCF3


12-4120
2,2,2-trichloroethyl
Me
H
F
CN
F
H
Br
H
nonafluoro-2-butyl
H
OCF3


12-4149
2,2,2-trichloroethyl
Me
H
F
CN
F
H
I
H
heptafluoroisopropyl
H
OCF3


12-4178
2,2,2-trichloroethyl
Me
H
F
CN
F
H
I
H
nonafluoro-2-butyl
H
OCF3


12-4197
2,2,2-trichloroethyl
Me
H
F
CN
F
H
F
H
heptafluoroisopropyl
H
CF3


12-4198
2,2,2-trichloroethyl
Me
H
F
CN
F
H
F
H
nonafluoro-2-butyl
H
CF3


12-4209
2,2,2-trichloroethyl
Me
H
F
CN
F
H
Cl
H
heptafluoroisopropyl
H
CF3


12-4238
2,2,2-trichloroethyl
Me
H
F
CN
F
H
Cl
H
nonafluoro-2-butyl
H
CF3


12-4267
2,2,2-trichloroethyl
Me
H
F
CN
F
H
Br
H
heptafluoroisopropyl
H
CF3


12-4296
2,2,2-trichloroethyl
Me
H
F
CN
F
H
Br
H
nonafluoro-2-butyl
H
CF3


12-4325
2,2,2-trichloroethyl
Me
H
F
CN
F
H
I
H
heptafluoroisopropyl
H
CF3


12-4354
2,2,2-trichloroethyl
Me
H
F
CN
F
H
I
H
nonafluoro-2-butyl
H
CF3


12-4383
2,2,2-trichloroethyl
Me
H
F
CN
F
H
OCF3
H
heptafluoroisopropyl
H
OCF3


12-4412
2,2,2-trichloroethyl
Me
H
F
CN
F
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


12-4441
2,2,2-trichloroethyl
Me
H
F
CN
F
H
CF3
H
heptafluoroisopropyl
H
OCF3


12-4470
2,2,2-trichloroethyl
Me
H
F
CN
F
H
CF3
H
nonafluoro-2-butyl
H
OCF3


12-4499
2,2,2-trichloroethyl
Me
H
F
CN
F
H
CF3
H
heptafluoroisopropyl
H
CF3


12-4528
2,2,2-trichloroethyl
Me
H
F
CN
F
H
CF3
H
nonafluoro-2-butyl
H
CF3











embedded image





















TABLE 13





compound














number
Q2
R1
R2
X1
X2
X3
X4
Y1
Y2
Y3
Y4
Y5







13-1
2,2,2-trichloroethyl
H
Me
H
H
H
H
F
H
heptafluoroisopropyl
H
OCF3


13-2
2,2,2-trichloroethyl
H
Me
H
H
H
H
F
H
nonafluoro-2-butyl
H
OCF3


13-13
2,2,2-trichloroethyl
H
Me
H
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


13-42
2,2,2-trichloroethyl
H
Me
H
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


13-71
2,2,2-trichloroethyl
H
Me
H
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


13-100
2,2,2-trichloroethyl
H
Me
H
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


13-129
2,2,2-trichloroethyl
H
Me
H
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


13-158
2,2,2-trichloroethyl
H
Me
H
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


13-177
2,2,2-trichloroethyl
H
Me
H
H
H
H
F
H
heptafluoroisopropyl
H
CF3


13-178
2,2,2-trichloroethyl
H
Me
H
H
H
H
F
H
nonafluoro-2-butyl
H
CF3


13-189
2,2,2-trichloroethyl
H
Me
H
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


13-218
2,2,2-trichloroethyl
H
Me
H
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


13-247
2,2,2-trichloroethyl
H
Me
H
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


13-276
2,2,2-trichloroethyl
H
Me
H
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


13-305
2,2,2-trichloroethyl
H
Me
H
H
H
H
I
H
heptafluoroisopropyl
H
CF3


13-334
2,2,2-trichloroethyl
H
Me
H
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


13-363
2,2,2-trichloroethyl
H
Me
H
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


13-392
2,2,2-trichloroethyl
H
Me
H
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


13-421
2,2,2-trichloroethyl
H
Me
H
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


13-450
2,2,2-trichloroethyl
H
Me
H
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


13-479
2,2,2-trichloroethyl
H
Me
H
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


13-508
2,2,2-trichloroethyl
H
Me
H
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


13-527
2,2,2-trichloroethyl
H
Me
F
H
H
H
F
H
heptafluoroisopropyl
H
F


13-528
2,2,2-trichloroethyl
H
Me
F
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


13-529
2,2,2-trichloroethyl
H
Me
F
H
H
H
Br
H
heptafluoroisopropyl
H
Br


13-530
2,2,2-trichloroethyl
H
Me
F
H
H
H
I
H
heptafluoroisopropyl
H
I


13-531
2,2,2-trichloroethyl
H
Me
F
H
H
H
F
H
heptafluoroisopropyl
H
OCF3


13-532
2,2,2-trichloroethyl
H
Me
F
H
H
H
F
H
nonafluoro-2-butyl
H
OCF3


13-543
2,2,2-trichloroethyl
H
Me
F
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


13-572
2,2,2-trichloroethyl
H
Me
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


13-601
2,2,2-trichloroethyl
H
Me
F
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


13-630
2,2,2-trichloroethyl
H
Me
F
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


13-659
2,2,2-trichloroethyl
H
Me
F
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


13-688
2,2,2-trichloroethyl
H
Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


13-707
2,2,2-trichloroethyl
H
Me
F
H
H
H
F
H
heptafluoroisopropyl
H
CF3


13-708
2,2,2-trichloroethyl
H
Me
F
H
H
H
F
H
nonafluoro-2-butyl
H
CF3


13-715
2-cyanoethyl
H
Et
F
H
H
H
Cl
H
heptafluoroisopropyl
H
C2F5


13-719
2,2,2-trichloroethyl
H
Me
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


13-721
n-propyl
H
Me
F
H
H
H
Cl
H
pentafluoroethyl
H
CF3


13-725
i-propyl
H
n-Pr
F
H
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


13-728
1,3-dichloro-2-propyl
H
Me
F
H
H
H
Cl
H
pentafluoroethyl
H
CF3


13-729
1-chloro-3-fluoro-2-propyl
H
i-Pr
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


13-733
i-butyl
H
CH2CH═CH2
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


13-739
ethyl
H
Me
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


13-744
2-cyanoethyl
H
CN
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


13-748
2,2,2-trichloroethyl
H
Me
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


13-750
n-propyl
H
CH2C═CH
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


13-762
i-butyl
H
NH2
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


13-773
2-cyanoethyl
H
Me
F
H
H
H
Br
H
heptafluoroisopropyl
H
C2F5


13-777
2,2,2-trichloroethyl
H
Me
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


13-779
n-propyl
H
C(O)OMe
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


13-784
1,2-difluoro-2-propyl
H
Me
F
H
H
H
Br
H
heptafluoroisopropyl
H
n-C3F7


13-790
4,4,4-trifluoro-n-butyl
H
Me
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


13-793
vinyl
H
C(O)C(O)OMe
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


13-806
2,2,2-trichloroethyl
H
Me
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


13-808
n-propyl
H
C(O)OEt
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


13-812
i-propyl
H
C(O)Me
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


13-819
4,4,4-trifluoro-n-butyl
H
Me
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


13-824
phenyl
H
C(O)C(O)OEt
F
H
H
H
Br
H
nonafluoro-2-butyl
H
i-C3F7


13-835
2,2,2-trichloroethyl
H
Me
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


13-840
3-bromo-n-propyl
H
C(O)Et
F
H
H
H
I
H
heptafluoroisopropyl
H
C2F5


13-848
4,4,4-trifluoro-n-butyl
H
Me
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


13-852
benzyl
H
S(O)2Me
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


13-860
2-cyanoethyl
H
S(O)2Et
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


13-864
2,2,2-trichloroethyl
H
Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


13-866
n-propyl
H
CH2Ph
F
H
H
H
I
H
nonafluoro-2-butyl
H
n-C3F7


13-870
i-propyl
H
CH2(3-Py)
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


13-877
4,4,4-trifluoro-n-butyl
H
Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


13-879
s-butyl
H
CH2(3-Py—N-
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3





oxide)


13-880
vinyl
H
Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
i-C3F7


13-893
2,2,2-trichloroethyl
H
Me
F
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


13-922
2,2,2-trichloroethyl
H
Me
F
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


13-951
2,2,2-trichloroethyl
H
Me
F
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


13-980
2,2,2-trichloroethyl
H
Me
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


13-1009
2,2,2-trichloroethyl
H
Me
F
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


13-1038
2,2,2-trichloroethyl
H
Me
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


13-1057
2,2,2-trichloroethyl
H
Me
H
F
H
H
F
H
heptafluoroisopropyl
H
F


13-1058
2,2,2-trichloroethYl
H
Me
H
F
H
H
F
H
nonafluoro-2-butyl
H
F


13-1069
2,2,2-trichloroethyl
H
Me
H
F
H
H
Cl
H
heptafluoroisopropyl
H
Cl


13-1098
2,2,2-trichloroethyl
H
Me
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


13-1127
2,2,2-trichloroethyl
H
Me
H
F
H
H
Br
H
heptafluoroisopropyl
H
Br


13-1156
2,2,2-trichloroethyl
H
Me
H
F
H
H
Br
H
nonafluoro-2-butyl
H
Br


13-1185
2,2,2-trichloroethyl
H
Me
H
F
H
H
I
H
heptafluoroisopropyl
H
I


13-1214
2,2,2-trichloroethyl
H
Me
H
F
H
H
I
H
nonafluoro-2-butyl
H
I


13-1236
2,2,2-trichloroethyl
H
Me
H
F
H
H
Cl
H
heptafluoroisopropyl
H
Br


13-1245
2,2,2-trichloroethyl
H
Me
H
F
H
H
F
H
heptafluoroisopropyl
H
OCF3


13-1246
2,2,2-trichloroethyl
H
Me
H
F
H
H
F
H
nonafluoro-2-butyl
H
OCF3


13-1257
2,2,2-trichloroethyl
H
Me
H
F
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


13-1286
2,2,2-trichloroethyl
H
Me
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


13-1315
2,2,2-trichloroethyl
H
Me
H
F
H
H
Br
H
heptafluoroisopropyl
H
OCF3


13-1344
2,2,2-trichloroethyl
H
Me
H
F
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


13-1373
2,2,2-trichloroethyl
H
Me
H
F
H
H
I
H
heptafluoroisopropyl
H
OCF3


13-1402
2,2,2-trichloroethyl
H
Me
H
F
H
H
I
H
nonafluoro-2-butyl
H
OCF3


13-1421
2,2,2-trichloroethyl
H
Me
H
F
H
H
F
H
heptafluoroisopropyl
H
CF3


13-1422
2,2,2-trichloroethyl
H
Me
H
F
H
H
F
H
nonafluoro-2-butyl
H
CF3


13-1433
2,2,2-trichloroethyl
H
Me
H
F
H
H
Cl
H
heptafluoroisopropyl
H
CF3


13-1462
2,2,2-trichloroethyl
H
Me
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


13-1491
2,2,2-trichloroethyl
H
Me
H
F
H
H
Br
H
heptafluoroisopropyl
H
CF3


13-1520
2,2,2-trichloroethyl
H
Me
H
F
H
H
Br
H
nonafluoro-2-butyl
H
CF3


13-1549
2,2,2-trichloroethyl
H
Me
H
F
H
H
I
H
heptafluoroisopropyl
H
CF3


13-1578
2,2,2-trichloroethyl
H
Me
H
F
H
H
I
H
nonafluoro-2-butyl
H
CF3


13-1607
2,2,2-trichloroethyl
H
Me
H
F
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


13-1636
2,2,2-trichloroethyl
H
Me
H
F
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


13-1665
2,2,2-trichloroethyl
H
Me
H
F
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


13-1694
2,2,2-trichloroethyl
H
Me
H
F
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


13-1723
2,2,2-trichloroethyl
H
Me
H
F
H
H
CF3
H
heptafluoroisopropyl
H
CF3


13-1752
2,2,2-trichloroethyl
H
Me
H
F
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


13-1771
2,2,2-trichloroethyl
H
Me
F
F
H
H
F
H
heptafluoroisopropyl
H
F


13-1772
2,2,2-trichloroethyl
H
Me
F
F
H
H
F
H
nonafluoro-2-butyl
H
F


13-1783
2,2,2-trichloroethyl
H
Me
F
F
H
H
Cl
H
heptafluoroisopropyl
H
Cl


13-1812
2,2,2-trichloroethyl
H
Me
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


13-1841
2,2,2-trichloroethyl
H
Me
F
F
H
H
Br
H
heptafluoroisopropyl
H
Br


13-1870
2,2,2-trichloroethyl
H
Me
F
F
H
H
Br
H
nonafluoro-2-butyl
H
Br


13-1899
2,2,2-trichloroethyl
H
Me
F
F
H
H
I
H
heptafluoroisopropyl
H
I


13-1928
2,2,2-trichloroethyl
H
Me
F
F
H
H
I
H
nonafluoro-2-butyl
H
I


13-1956
2,2,2-trichloroethyl
H
Me
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
Br


13-1959
2,2,2-trichloroethyl
H
Me
F
F
H
H
F
H
heptafluoroisopropyl
H
OCF3


13-1960
2,2,2-trichloroethyl
H
Me
F
F
H
H
F
H
nonafluoro-2-butyl
H
OCF3


13-1971
2,2,2-trichloroethyl
H
Me
F
F
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


13-2000
2,2,2-trichloroethyl
H
Me
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


13-2029
2,2,2-trichloroethyl
H
Me
F
F
H
H
Br
H
heptafluoroisopropyl
H
OCF3


13-2058
2,2,2-trichloroethyl
H
Me
F
F
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


13-2087
2,2,2-trichloroethyl
H
Me
F
F
H
H
I
H
heptafluoroisopropyl
H
OCF3


13-2116
2,2,2-trichloroethyl
H
Me
F
F
H
H
I
H
nonafluoro-2-butyl
H
OCF3


13-2135
2,2,2-trichloroethyl
H
Me
F
F
H
H
F
H
heptafluoroisopropyl
H
CF3


13-2136
2,2,2-trichloroethyl
H
Me
F
F
H
H
F
H
nonafluoro-2-butyl
H
CF3


13-2147
2,2,2-trichloroethyl
H
Me
F
F
H
H
Cl
H
heptafluoroisopropyl
H
CF3


13-2176
2,2,2-trichloroethyl
H
Me
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


13-2205
2,2,2-trichloroethyl
H
Me
F
F
H
H
Br
H
heptafluoroisopropyl
H
CF3


13-2234
2,2,2-trichloroethyl
H
Me
F
F
H
H
Br
H
nonafluoro-2-butyl
H
CF3


13-2263
2,2,2-trichloroethyl
H
Me
F
F
H
H
I
H
heptafluoroisopropyl
H
CF3


13-2292
2,2,2-trichloroethyl
H
Me
F
F
H
H
I
H
nonafluoro-2-butyl
H
CF3


13-2321
2,2,2-trichloroethyl
H
Me
F
F
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


13-2350
2,2,2-trichloroethyl
H
Me
F
F
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


13-2379
2,2,2-trichloroethyl
H
Me
F
F
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


13-2408
2,2,2-trichloroethyl
H
Me
F
F
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


13-2437
2,2,2-trichloroethyl
H
Me
F
F
H
H
CF3
H
heptafluoroisopropyl
H
CF3


13-2439
n-propyl
H
S(O)2Me
F
F
H
H
CF3
H
heptafluoroisopropyl
H
CF3


13-2466
2,2,2-trichloroethyl
H
Me
F
F
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


13-2485
2,2,2-trichloroethyl
H
Me
F
F
F
H
Cl
H
pentafluoroethyl
H
Cl


13-2486
2,2,2-trichloroethyl
H
Me
F
F
F
H
Br
H
heptafluoroisopropyl
H
Br


13-2487
2,2,2-trichloroethyl
H
Me
F
F
F
H
Br
H
heptafluoroisopropyl
H
OCF3


13-2488
2,2,2-trichloroethyl
H
Me
F
F
F
H
I
H
heptafluoroisopropyl
H
CF3


13-2489
2,2,2-trichloroethyl
H
Me
F
F
F
H
CF3
H
heptafluoroisopropyl
H
CF3


13-2490
2,2,2-trichloroethyl
H
Me
F
F
F
H
I
H
nonafluoro-2-butyl
H
I


13-2491
2,2,2-trichloroethyl
H
Me
F
F
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


13-2492
2,2,2-trichloroethyl
H
Me
F
F
F
H
Br
H
nonafluoro-2-butyl
H
CF3


13-2493
2,2,2-trichloroethyl
H
Me
F
F
F
H
CF3
H
nonafluoro-2-butyl
H
CF3


13-2494
2,2,2-trichloroethyl
H
Me
H
H
F
H
Cl
H
pentafluoroethyl
H
Cl


13-2495
2,2,2-trichloroethyl
H
Me
H
H
F
H
Br
H
heptafluoroisopropyl
H
Br


13-2496
2,2,2-trichloroethyl
H
Me
H
H
F
H
Br
H
heptafluoroisopropyl
H
OCF3


13-2497
2,2,2-trichloroethyl
H
Me
H
H
F
H
I
H
heptafluoroisopropyl
H
CF3


13-2498
2,2,2-trichloroethyl
H
Me
H
H
F
H
CF3
H
heptafluoroisopropyl
H
CF3


13-2499
2,2,2-trichloroethyl
H
Me
H
H
F
H
I
H
nonafluoro-2-butyl
H
I


13-2500
2,2,2-trichloroethyl
H
Me
H
H
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


13-2501
2,2,2-trichloroethyl
H
Me
H
H
F
H
Br
H
nonafluoro-2-butyl
H
CF3


13-2502
2,2,2-trichloroethyl
H
Me
H
H
F
H
CF3
H
nonafluoro-2-butyl
H
CF3


13-2503
2,2,2-trichloroethyl
H
Me
H
H
H
F
Cl
H
pentafluoroethyl
H
Cl


13-2504
2,2,2-trichloroethyl
H
Me
H
H
H
F
Br
H
heptafluoroisopropyl
H
Br


13-2505
2,2,2-trichloroethyl
H
Me
H
H
H
F
Br
H
heptafluoroisopropyl
H
OCF3


13-2506
2,2,2-trichloroethyl
H
Me
H
H
H
F
I
H
heptafluoroisopropyl
H
CF3


13-2507
2,2,2-trichloroethyl
H
Me
H
H
H
F
CF3
H
heptafluoroisopropyl
H
CF3


13-2508
2,2,2-trichloroethyl
H
Me
H
H
H
F
I
H
nonafluoro-2-butyl
H
I


13-2509
2,2,2-trichloroethyl
H
Me
H
H
H
F
Cl
H
nonafluoro-2-butyl
H
OCF3


13-2510
2,2,2-trichloroethyl
H
Me
H
H
H
F
Br
H
nonafluoro-2-butyl
H
CF3


13-2511
2,2,2-trichloroethyl
H
Me
H
H
H
F
CF3
H
nonafluoro-2-butyl
H
CF3


13-2512
2,2,2-trichloroethyl
H
Me
F
H
F
H
Cl
H
pentafluoroethyl
H
Cl


13-2513
2,2,2-trichloroethyl
H
Me
F
H
F
H
Br
H
heptafluoroisopropyl
H
Br


13-2514
2,2,2-trichloroethyl
H
Me
F
H
F
H
Br
H
heptafluoroisopropyl
H
OCF3


13-2515
2,2,2-trichloroethyl
H
Me
F
H
F
H
I
H
heptafluoroisopropyl
H
CF3


13-2516
2,2,2-trichloroethyl
H
Me
F
H
F
H
CF3
H
heptafluoroisopropyl
H
CF3


13-2517
2,2,2-trichloroethyl
H
Me
F
H
F
H
I
H
nonafluoro-2-butyl
H
I


13-2518
2,2,2-trichloroethyl
H
Me
F
H
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


13-2519
2,2,2-trichloroethyl
H
Me
F
H
F
H
Br
H
nonafluoro-2-butyl
H
CF3


13-2520
2,2,2-trichloroethyl
H
Me
F
H
F
H
CF3
H
nonafluoro-2-butyl
H
CF3


13-2521
2,2,2-trichloroethyl
H
Me
F
H
H
F
Cl
H
pentafluoroethyl
H
Cl


13-2522
2,2,2-trichloroethyl
H
Me
F
H
H
F
Br
H
heptafluoroisopropyl
H
Br


13-2523
2,2,2-trichloroethyl
H
Me
F
H
H
F
Br
H
heptafluoroisopropyl
H
OCF3


13-2524
2,2,2-trichloroethyl
H
Me
F
H
H
F
I
H
heptafluoroisopropyl
H
CF3


13-2525
2,2,2-trichloroethyl
H
Me
F
H
H
F
CF3
H
heptafluoroisopropyl
H
CF3


13-2526
2,2,2-trichloroethyl
H
Me
F
H
H
F
I
H
nonafluoro-2-butyl
H
I


13-2527
2,2,2-trichloroethyl
H
Me
F
H
H
F
Cl
H
nonafluoro-2-butyl
H
OCF3


13-2528
2,2,2-trichloroethyl
H
Me
F
H
H
F
Br
H
nonafluoro-2-butyl
H
CF3


13-2529
2,2,2-trichloroethyl
H
Me
F
H
H
F
CF3
H
nonafluoro-2-butyl
H
CF3


13-2530
2,2,2-trichloroethyl
H
Me
H
F
F
H
Cl
H
pentafluoroethyl
H
Cl


13-2531
2,2,2-trichloroethyl
H
Me
H
F
F
H
Br
H
heptafluoroisopropyl
H
Br


13-2532
2,2,2-trichloroethyl
H
Me
H
F
F
H
Br
H
heptafluoroisopropyl
H
OCF3


13-2533
2,2,2-trichloroethyl
H
Me
H
F
F
H
I
H
heptafluoroisopropyl
H
CF3


13-2534
2,2,2-trichloroethyl
H
Me
H
F
F
H
CF3
H
heptafluoroisopropyl
H
CF3


13-2535
2,2,2-trichloroethyl
H
Me
H
F
F
H
I
H
nonafluoro-2-butyl
H
I


13-2536
2,2,2-trichloroethyl
H
Me
H
F
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


13-2537
2,2,2-trichloroethyl
H
Me
H
F
F
H
Br
H
nonafluoro-2-butyl
H
CF3


13-2538
2,2,2-trichloroethyl
H
Me
H
F
F
H
CF3
H
nonafluoro-2-butyl
H
CF3


13-2539
2,2,2-trichloroethyl
H
Me
H
F
H
F
Cl
H
pentafluoroethyl
H
Cl


13-2540
2,2,2-trichloroethyl
H
Me
H
F
H
F
Br
H
heptafluoroisopropyl
H
Br


13-2541
2,2,2-trichloroethyl
H
Me
H
F
H
F
Br
H
heptafluoroisopropyl
H
OCF3


13-2542
2,2,2-trichloroethyl
H
Me
H
F
H
F
I
H
heptafluoroisopropyl
H
CF3


13-2543
2,2,2-trichloroethyl
H
Me
H
F
H
F
CF3
H
heptafluoroisopropyl
H
CF3


13-2544
2,2,2-trichloroethyl
H
Me
H
F
H
F
I
H
nonafluoro-2-butyl
H
I


13-2545
2,2,2-trichloroethyl
H
Me
H
F
H
F
Cl
H
nonafluoro-2-butyl
H
OCF3


13-2546
2,2,2-trichloroethyl
H
Me
H
F
H
F
Br
H
nonafluoro-2-butyl
H
CF3


13-2547
2,2,2-trichloroethyl
H
Me
H
F
H
F
CF3
H
nonafluoro-2-butyl
H
CF3


13-2548
2,2,2-trichloroethyl
H
Me
H
H
F
F
Cl
H
pentafluoroethyl
H
Cl


13-2549
2,2,2-trichloroethyl
H
Me
H
H
F
F
Br
H
heptafluoroisopropyl
H
Br


13-2550
2,2,2-trichloroethyl
H
Me
H
H
F
F
Br
H
heptafluoroisopropyl
H
OCF3


13-2551
2,2,2-trichloroethyl
H
Me
H
H
F
F
I
H
heptafluoroisopropyl
H
CF3


13-2552
2,2,2-trichloroethyl
H
Me
H
H
F
F
CF3
H
heptafluoroisopropyl
H
CF3


13-2553
2,2,2-trichloroethyl
H
Me
H
H
F
F
I
H
nonafluoro-2-butyl
H
I


13-2554
2,2,2-trichloroethyl
H
Me
H
H
F
F
Cl
H
nonafluoro-2-butyl
H
OCF3


13-2555
2,2,2-trichloroethyl
H
Me
H
H
F
F
Br
H
nonafluoro-2-butyl
H
CF3


13-2556
2,2,2-trichloroethyl
H
Me
H
H
F
F
CF3
H
nonafluoro-2-butyl
H
CF3


13-2557
2,2,2-trichloroethyl
H
Me
F
F
H
F
Cl
H
pentafluoroethyl
H
Cl


13-2558
2,2,2-trichloroethyl
H
Me
F
F
H
F
Br
H
heptafluoroisopropyl
H
Br


13-2559
2,2,2-trichloroethyl
H
Me
F
F
H
F
Br
H
heptafluoroisopropyl
H
OCF3


13-2560
2,2,2-trichloroethyl
H
Me
F
F
H
F
I
H
heptafluoroisopropyl
H
CF3


13-2561
2,2,2-trichloroethyl
H
Me
F
F
H
F
CF3
H
heptafluoroisopropyl
H
CF3


13-2562
2,2,2-trichloroethyl
H
Me
F
F
H
F
I
H
nonafluoro-2-butyl
H
I


13-2563
2,2,2-trichloroethyl
H
Me
F
F
H
F
Cl
H
nonafluoro-2-butyl
H
OCF3


13-2564
2,2,2-trichloroethyl
H
Me
F
F
H
F
Br
H
nonafluoro-2-butyl
H
CF3


13-2565
2,2,2-trichloroethyl
H
Me
F
F
H
F
CF3
H
nonafluoro-2-butyl
H
CF3


13-2566
2,2,2-trichloroethyl
H
Me
F
H
F
F
Cl
H
pentafluoroethyl
H
Cl


13-2567
2,2,2-trichloroethyl
H
Me
F
H
F
F
Br
H
heptafluoroisopropyl
H
Br


13-2568
2,2,2-trichloroethyl
H
Me
F
H
F
F
Br
H
heptafluoroisopropyl
H
OCF3


13-2569
2,2,2-trichloroethyl
H
Me
F
H
F
F
I
H
heptafluoroisopropyl
H
CF3


13-2570
2,2,2-trichloroethyl
H
Me
F
H
F
F
CF3
H
heptafluoroisopropyl
H
CF3


13-2571
2,2,2-trichloroethyl
H
Me
F
H
F
F
I
H
nonafluoro-2-butyl
H
I


13-2572
2,2,2-trichloroethyl
H
Me
F
H
F
F
Cl
H
nonafluoro-2-butyl
H
OCF3


13-2573
2,2,2-trichloroethyl
H
Me
F
H
F
F
Br
H
nonafluoro-2-butyl
H
CF3


13-2574
2,2,2-trichloroethyl
H
Me
F
H
F
F
CF3
H
nonafluoro-2-butyl
H
CF3


13-2575
2,2,2-trichloroethyl
H
Me
H
F
F
F
Cl
H
pentafluoroethyl
H
Cl


13-2576
2,2,2-trichloroethyl
H
Me
H
F
F
F
Br
H
heptafluoroisopropyl
H
Br


13-2577
2,2,2-trichloroethyl
H
Me
H
F
F
F
Br
H
heptafluoroisopropyl
H
OCF3


13-2578
2,2,2-trichloroethyl
H
Me
H
F
F
F
I
H
heptafluoroisopropyl
H
CF3


13-2579
2,2,2-trichloroethyl
H
Me
H
F
F
F
CF3
H
heptafluoroisopropyl
H
CF3


13-2580
2,2,2-trichloroethyl
H
Me
H
F
F
F
I
H
nonafluoro-2-butyl
H
I


13-2581
2,2,2-trichloroethyl
H
Me
H
F
F
F
Cl
H
nonafluoro-2-butyl
H
OCF3


13-2582
2,2,2-trichloroethyl
H
Me
H
F
F
F
Br
H
nonafluoro-2-butyl
H
CF3


13-2583
2,2,2-trichloroethyl
H
Me
H
F
F
F
CF3
H
nonafluoro-2-butyl
H
CF3


13-2584
2,2,2-trichloroethyl
H
Me
F
F
F
F
Cl
H
pentafluoroethyl
H
Cl


13-2585
2,2,2-trichloroethyl
H
Me
F
F
F
F
Br
H
heptafluoroisopropyl
H
Br


13-2586
2,2,2-trichloroethyl
H
Me
F
F
F
F
Br
H
heptafluoroisopropyl
H
OCF3


13-2587
2,2,2-trichloroethyl
H
Me
F
F
F
F
I
H
heptafluoroisopropyl
H
CF3


13-2588
2,2,2-trichloroethyl
H
Me
F
F
F
F
CF3
H
heptafluoroisopropyl
H
CF3


13-2589
2,2,2-trichloroethyl
H
Me
F
F
F
F
I
H
nonafluoro-2-butyl
H
I


13-2590
2,2,2-trichloroethyl
H
Me
F
F
F
F
Cl
H
nonafluoro-2-butyl
H
OCF3


13-2591
2,2,2-trichloroethyl
H
Me
F
F
F
F
Br
H
nonafluoro-2-butyl
H
CF3


13-2592
2,2,2-trichloroethyl
H
Me
F
F
F
F
CF3
H
nonafluoro-2-butyl
H
CF3


13-2593
2,2,2-trichloroethyl
H
Me
H
CN
H
H
F
H
heptafluoroisopropyl
H
OCF3


13-2594
2,2,2-trichloroethyl
H
Me
H
CN
H
H
F
H
nonafluoro-2-butyl
H
OCF3


13-2605
2,2,2-trichloroethyl
H
Me
H
ON
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


13-2634
2,2,2-trichloroethyl
H
Me
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


13-2663
2,2,2-trichloroethyl
H
Me
H
CN
H
H
Br
H
heptafluoroisopropyl
H
OCF3


13-2692
2,2,2-trichloroethyl
H
Me
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


13-2721
2,2,2-trichloroethyl
H
Me
H
CN
H
H
I
H
heptafluoroisopropyl
H
OCF3


13-2750
2,2,2-trichloroethyl
H
Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
OCF3


13-2769
2,2,2-trichloroethyl
H
Me
H
CN
H
H
F
H
heptafluoroisopropyl
H
CF3


13-2770
2,2,2-trichloroethyl
H
Me
H
CN
H
H
F
H
nonafluoro-2-butyl
H
CF3


13-2781
2,2,2-trichloroethyl
H
Me
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


13-2810
2,2,2-trichloroethyl
H
Me
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


13-2839
2,2,2-trichloroethyl
H
Me
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


13-2868
2,2,2-trichloroethyl
H
Me
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


13-2897
2,2,2-trichloroethyl
H
Me
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


13-2926
2,2,2-trichloroethyl
H
Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


13-2955
2,2,2-trichloroethyl
H
Me
H
CN
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


13-2984
2,2,2-trichloroethyl
H
Me
H
CN
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


13-3013
2,2,2-trichloroethyl
H
Me
H
CN
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


13-3042
2,2,2-trichloroethyl
H
Me
H
CN
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


13-3071
2,2,2-trichloroethyl
H
Me
H
CN
H
H
CF3
H
heptafluoroisopropyl
H
CF3


13-3100
2,2,2-trichloroethyl
H
Me
H
CN
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


13-3119
2,2,2-trichloroethyl
H
Me
F
CN
H
H
F
H
heptafluoroisopropyl
H
F


13-3120
2,2,2-trichloroethyl
H
Me
F
CN
H
H
F
H
nonafluoro-2-butyl
H
F


13-3131
2,2,2-trichloroethyl
H
Me
F
CN
H
H
Cl
H
heptafluoroisopropyl
H
Cl


13-3160
2,2,2-trichloroethyl
H
Me
F
CN
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


13-3189
2,2,2-trichloroethyl
H
Me
F
CN
H
H
Br
H
heptafluoroisopropyl
H
Br


13-3218
2,2,2-trichloroethyl
H
Me
F
CN
H
H
Br
H
nonafluoro-2-butyl
H
Br


13-3247
2,2,2-trichloroethyl
H
Me
F
CN
H
H
I
H
heptafluoroisopropyl
H
I


13-3276
2,2,2-trichloroethyl
H
Me
F
CN
H
H
I
H
nonafluoro-2-butyl
H
I


13-3298
2,2,2-trichloroethyl
H
Me
F
CN
H
H
Cl
H
heptafluoroisopropyl
H
Br


13-3307
2,2,2-trichloroethyl
H
Me
F
CN
H
H
F
H
heptafluoroisopropyl
H
OCF3


13-3308
2,2,2-trichloroethyl
H
Me
F
CN
H
H
F
H
nonafluoro-2-butyl
H
OCF3


13-3319
2,2,2-trichloroethyl
H
Me
F
CN
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


13-3348
2,2,2-trichloroethyl
H
Me
F
CN
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


13-3377
2,2,2-trichloroethyl
H
Me
F
CN
H
H
Br
H
heptafluoroisopropyl
H
OCF3


13-3406
2,2,2-trichloroethyl
H
Me
F
CN
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


13-3435
2,2,2-trichloroethyl
H
Me
F
CN
H
H
I
H
heptafluoroisopropyl
H
OCF3


13-3464
2,2,2-trichloroethyl
H
Me
F
CN
H
H
I
H
nonafluoro-2-butyl
H
OCF3


13-3483
2,2,2-trichloroethyl
H
Me
F
CN
H
H
F
H
heptafluoroisopropyl
H
CF3


13-3484
2,2,2-trichloroethyl
H
Me
F
CN
H
H
F
H
nonafluoro-2-butyl
H
CF3


13-3495
2,2,2-trichloroethyl
H
Me
F
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


13-3524
2,2,2-trichloroethyl
H
Me
F
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


13-3553
2,2,2-trichloroethyl
H
Me
F
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


13-3582
2,2,2-trichloroethyl
H
Me
F
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


13-3611
2,2,2-trichloroethyl
H
Me
F
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


13-3640
2,2,2-trichloroethyl
H
Me
F
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


13-3669
2,2,2-trichloroethyl
H
Me
F
CN
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


13-3698
2,2,2-trichloroethyl
H
Me
F
CN
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


13-3727
2,2,2-trichloroethyl
H
Me
F
CN
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


13-3756
2,2,2-trichloroethyl
H
Me
F
CN
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


13-3785
2,2,2-trichloroethyl
H
Me
F
CN
H
H
CF3
H
heptafluoroisopropyl
H
CF3


13-3814
2,2,2-trichloroethyl
H
Me
F
CN
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


13-3833
2,2,2-trichloroethyl
H
Me
F
CN
F
H
F
H
heptafluoroisopropyl
H
F


13-3834
2,2,2-trichloroethyl
H
Me
F
CN
F
H
F
H
nonafluoro-2-butyl
H
F


13-3845
2,2,2-trichloroethyl
H
Me
F
CN
F
H
Cl
H
heptafluoroisopropyl
H
Cl


13-3874
2,2,2-trichloroethyl
H
Me
F
CN
F
H
Cl
H
nonafluoro-2-butyl
H
Cl


13-3903
2,2,2-trichloroethyl
H
Me
F
CN
F
H
Br
H
heptafluoroisopropyl
H
Br


13-3932
2,2,2-trichloroethyl
H
Me
F
CN
F
H
Br
H
nonafluoro-2-butyl
H
Br


13-3961
2,2,2-trichloroethyl
H
Me
F
CN
F
H
I
H
heptafluoroisopropyl
H
I


13-3990
2,2,2-trichloroethyl
H
Me
F
CN
F
H
I
H
nonafluoro-2-butyl
H
I


13-4012
2,2,2-trichloroethyl
H
Me
F
CN
F
H
Cl
H
heptafluoroisopropyl
H
Br


13-4021
2,2,2-trichloroethyl
H
Me
F
CN
F
H
F
H
heptafluoroisopropyl
H
OCF3


13-4022
2,2,2-trichloroethyl
H
Me
F
CN
F
H
F
H
nonafluoro-2-butyl
H
OCF3


13-4033
2,2,2-trichloroethyl
H
Me
F
CN
F
H
Cl
H
heptafluoroisopropyl
H
OCF3


13-4062
2,2,2-trichloroethyl
H
Me
F
CN
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


13-4091
2,2,2-trichloroethyl
H
Me
F
CN
F
H
Br
H
heptafluoroisopropyl
H
OCF3


13-4120
2,2,2-trichloroethyl
H
Me
F
CN
F
H
Br
H
nonafluoro-2-butyl
H
OCF3


13-4149
2,2,2-trichloroethyl
H
Me
F
CN
F
H
I
H
heptafluoroisopropyl
H
OOF3


13-4178
2,2,2-trichloroethyl
H
Me
F
CN
F
H
I
H
nonafluoro-2-butyl
H
OCF3


13-4197
2,2,2-trichloroethyl
H
Me
F
CN
F
H
F
H
heptafluoroisopropyl
H
CF3


13-4198
2,2,2-trichloroethyl
H
Me
F
CN
F
H
F
H
nonafluoro-2-butyl
H
CF3


13-4209
2,2,2-trichloroethyl
H
Me
F
CN
F
H
Cl
H
heptafluoroisopropyl
H
CF3


13-4238
2,2,2-trichloroethyl
H
Me
F
CN
F
H
Cl
H
nonafluoro-2-butyl
H
CF3


13-4267
2,2,2-trichloroethyl
H
Me
F
CN
F
H
Br
H
heptafluoroisopropyl
H
CF3


13-4296
2,2,2-trichloroethyl
H
Me
F
CN
F
H
Br
H
nonafluoro-2-butyl
H
CF3


13-4325
2,2,2-trichloroethyl
H
Me
F
CN
F
H
I
H
heptafluoroisopropyl
H
CF3


13-4354
2,2,2-trichloroethyl
H
Me
F
CN
F
H
I
H
nonafluoro-2-butyl
H
CF3


13-4383
2,2,2-trichloroethyl
H
Me
F
CN
F
H
OCF3
H
heptafluoroisopropyl
H
OCF3


13-4412
2,2,2-trichloroethyl
H
Me
F
CN
F
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


13-4441
2,2,2-trichloroethyl
H
Me
F
CN
F
H
CF3
H
heptafluoroisopropyl
H
OCF3


13-4470
2,2,2-trichloroethyl
H
Me
F
CN
F
H
CF3
H
nonafluoro-2-butyl
H
OCF3


13-4499
2,2,2-trichloroethyl
H
Me
F
CN
F
H
CF3
H
heptafluoroisopropyl
H
CF3


13-4528
2,2,2-trichloroethyl
H
Me
F
CN
F
H
CF3
H
nonafluoro-2-butyl
H
CF3











embedded image





















TABLE 14





compound














number
Q2
R1
R2
X1
X2
X3
X4
Y1
Y2
Y3
Y4
Y5







14-1
2,2,2-trichloroethyl
Me
Me
H
H
H
H
F
H
heptafluoroisopropyl
H
OCF3


14-2
2,2,2-trichloroethyl
Me
Me
H
H
H
H
F
H
nonafluoro-2-butyl
H
OCF3


14-13
2,2,2-trichloroethyl
Me
Me
H
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


14-42
2,2,2-trichloroethyl
Me
Me
H
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


14-71
2,2,2-trichloroethyl
Me
Me
H
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


14-100
2,2,2-trichloroethyl
Me
Me
H
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


14-129
2,2,2-trichloroethyl
Me
Me
H
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


14-158
2,2,2-trichloroethyl
Me
Me
H
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


14-373
2,2,2-trichloroethyl
Me
Me
H
H
H
H
F
H
heptafluoroisopropyl
H
CF3


14-374
2,2,2-trichloroethyl
Me
Me
H
H
H
H
F
H
nonafluoro-2-butyl
H
CF3


14-385
2,2,2-trichloroethyl
Me
Me
H
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


14-414
2,2,2-trichloroethyl
Me
Me
H
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


14-443
2,2,2-trichloroethyl
Me
Me
H
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


14-472
2,2,2-trichloroethyl
Me
Me
H
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


14-501
2,2,2-trichloroethyl
Me
Me
H
H
H
H
I
H
heptafluoroisopropyl
H
CF3


14-530
2,2,2-trichloroethyl
Me
Me
H
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-755
2,2,2-trichloroethyl
Me
Me
H
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


14-784
2,2,2-trichloroethyl
Me
Me
H
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


14-813
2,2,2-trichloroethyl
Me
Me
H
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


14-842
2,2,2-trichloroethyl
Me
Me
H
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


14-871
2,2,2-trichloroethyl
Me
Me
H
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


14-900
2,2,2-trichloroethyl
Me
Me
H
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


14-1115
2,2,2-trichloroethyl
Me
Me
F
H
H
H
F
H
heptafluoroisopropyl
H
F


14-1116
2,2,2-trichloroethyl
Me
Me
F
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


14-1117
2,2,2-trichloroethyl
Me
Me
F
H
H
H
Br
H
heptafluoroisopropyl
H
Br


14-1118
2,2,2-trichloroethyl
Me
Me
F
H
H
H
I
H
heptafluoroisopropyl
H
I


14-1119
2,2,2-trichloroethyl
Me
Me
F
H
H
H
F
H
heptafluoroisopropyl
H
OCF3


14-1120
2,2,2-trichloroethyl
Me
Me
F
H
H
H
F
H
nonafluoro-2-butyl
H
OCF3


14-1131
2,2,2-trichloroethyl
Me
Me
F
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


14-1160
2,2,2-trichloroethyl
Me
Me
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


14-1189
2,2,2-trichloroethyl
Me
Me
F
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


14-1218
2,2,2-trichloroethyl
Me
Me
F
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


14-1247
2,2,2-trichloroethyl
Me
Me
F
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


14-1276
2,2,2-trichloroethyl
Me
Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


14-1491
2,2,2-trichloroethyl
Me
Me
F
H
H
H
F
H
heptafluoroisopropyl
H
CF3


14-1492
2,2,2-trichloroethyl
Me
Me
F
H
H
H
F
H
nonafluoro-2-butyl
H
CF3


14-1498
2-iodoethyl
Me
Et
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


14-1499
2-cyanoethyl
Et
Me
F
H
H
H
Cl
H
heptafluoroisopropyl
H
C2F5


14-1503
2,2,2-trichloroethyl
Me
Me
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


14-1505
n-propyl
Me
n-Pr
F
H
H
H
Cl
H
pentafluoroethyl
H
CF3


14-1509
i-propyl
n-Pr
Me
F
H
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


14-1512
1,3-dichloro-2-propyl
Me
Me
F
H
H
H
Cl
H
pentafluoroethyl
H
CF3


14-1513
1-chloro-3-fluoro-2-propyl
i-Pr
Me
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


14-1515
n-butyl
Me
i-Pr
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


14-1517
i-butyl
CH2CH═CH2
Me
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


14-1518
s-butyl
Me
CH2CH═CH2
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


14-1519
vinyl
Me
CN
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


14-1523
ethyl
Me
Me
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


14-1528
2-cyanoethyl
CN
Me
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


14-1532
2,2,2-trichloroethyl
Me
Me
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


14-1533
2,2,2-tribromoethyl
Me
CH2C≡CH
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


14-1534
n-propyl
CH2C≡CH
Me
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


14-1544
n-butyl
Me
NH2
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


14-1546
i-butyl
NH2
Me
F
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


14-1557
2-cyanoethyl
Me
C(O)OMe
F
H
H
H
Br
H
heptafluoroisopropyl
H
C2F5


14-1561
2,2,2-trichloroethyl
Me
Me
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


14-1563
n-propyl
C(O)OMe
Me
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


14-1568
1,2-difluoro-2-propyl
Me
Me
F
H
H
H
Br
H
heptafluoroisopropyl
H
n-C3F7


14-1574
4,4,4-trifluoro-n-butyl
Me
Me
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


14-1575
i-butyl
Me
C(O)C(O)OMe
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


14-1577
vinyl
C(O)C(O)OMe
Me
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


14-1586
2-cyanoethyl
Me
C(O)OEt
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


14-1590
2,2,2-trichloroethyl
Me
Me
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


14-1592
n-propyl
C(O)OEt
Me
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


14-1595
3-bromo-n-propyl
Me
C(O)Me
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


14-1596
i-propyl
C(O)Me
Me
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


14-1603
4,4,4-trifluoro-n-butyl
Me
Me
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


14-1604
i-butyl
Me
C(O)C(O)OEt
F
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


14-1608
phenyl
C(O)C(O)OEt
Me
F
H
H
H
Br
H
nonafluoro-2-butyl
H
i-C3F7


14-1619
2,2,2-trichloroethyl
Me
Me
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


14-1621
n-propyl
Me
C(O)Et
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


14-1624
3-bromo-n-propyl
C(O)Et
Me
F
H
H
H
I
H
heptafluoroisopropyl
H
C2F5


14-1632
4,4,4-trifluoro-n-butyl
Me
Me
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


14-1633
i-butyl
Me
S(O)2Me
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


14-1636
benzyl
S(O)2Me
Me
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


14-1643
2-iodoethyl
Me
S(O)2Et
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1644
2-cyanoethyl
S(O)2Et
Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1648
2,2,2-trichloroethyl
Me
Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1649
2,2,2-tribromoethyl
Me
CH2Ph
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1650
n-propyl
CH2Ph
Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
n-C3F7


14-1654
i-propyl
CH2(3-Py)
Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1660
n-butyl
Me
CH2(3-Py)
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1661
4,4,4-trifluoro-n-butyl
Me
Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1663
s-butyl
CH2(3-Py—N-
Me
F
H
H
H
H
H
nonafluoro-2-butyl
H
CF3




oxide)


14-1664
vinyl
Me
Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
i-C3F7


14-1666
phenyl
Me
CH2(3-Py—N-
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3





oxide)


14-1667
2,2,2-trichloroethyl
Et
Et
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1668
2,2,2-trichloroethyl
Et
n-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1669
2,2,2-trichloroethyl
Et
i-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1670
2,2,2-trichloroethyl
Et
CH2CH═CH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1671
2,2,2-trichloroethyl
Et
CN
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1672
2,2,2-trichloroethyl
Et
CH2C≡CH
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1673
2,2,2-trichloroethyl
Et
NH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1674
2,2,2-trichloroethyl
Et
C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1675
2,2,2-trichloroethyl
Et
C(O)C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1676
2,2,2-trichloroethyl
Et
C(O)Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1677
2,2,2-trichloroethyl
Et
S(O)2Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1678
2,2,2-trichloroethyl
Et
CH2Ph
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1679
2,2,2-trichloroethyl
Et
CH2(3-Py)
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1680
2,2,2-trichloroethyl
Et
CH2(3-Py—N-
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3





oxide)


14-1681
2,2,2-trichloroethyl
n-Pr
Et
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1682
2,2,2-trichloroethyl
n-Pr
n-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1683
2,2,2-trichloroethyl
n-Pr
i-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1684
2,2,2-trichloroethyl
n-Pr
CH2CH═CH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1685
2,2,2-trichloroethyl
n-Pr
CN
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1686
2,2,2-trichloroethyl
n-Pr
CH2C≡CH
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1687
2,2,2-trichloroethyl
n-Pr
NH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1688
2,2,2-trichloroethyl
n-Pr
C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1689
2,2,2-trichloroethyl
n-Pr
C(O)C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1690
2,2,2-trichloroethyl
n-Pr
C(O)Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1691
2,2,2-trichloroethyl
n-Pr
S(O)2Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1692
2,2,2-trichloroethyl
n-Pr
CH2Ph
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1693
2,2,2-trichloroethyl
n-Pr
CH2(3-Py)
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1694
2,2,2-trichloroethyl
n-Pr
CH2(3-Py—N-
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3





oxide)


14-1695
2,2,2-trichloroethyl
i-Pr
Et
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1696
2,2,2-trichloroethyl
i-Pr
n-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1697
2,2,2-trichloroethyl
i-Pr
i-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1698
2,2,2-trichloroethyl
i-Pr
CH2CH═CH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1699
2,2,2-trichloroethyl
i-Pr
CN
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1700
2,2,2-trichloroethyl
i-Pr
CH2C≡CH
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1701
2,2,2-trichloroethyl
i-Pr
NH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1702
2,2,2-trichloroethyl
i-Pr
C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1703
2,2,2-trichloroethyl
i-Pr
C(O)C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1704
2,2,2-trichloroethyl
i-Pr
C(O)Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1705
2,2,2-trichloroethyl
i-Pr
S(O)2Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1706
2,2,2-trichloroethyl
i-Pr
CH2Ph
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1707
2,2,2-trichloroethyl
i-Pr
CH2(3-Py)
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1708
2,2,2-trichloroethyl
i-Pr
CH2(3-Py—N-
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3





oxide)


14-1709
2,2,2-trichloroethyl
CH2CH═CH2
Et
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1710
2,2,2-trichloroethyl
CH2CH═CH2
n-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1711
2,2,2-trichloroethyl
CH2CH═CH2
i-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1712
2,2,2-trichloroethyl
CH2CH═CH2
CH2CH═CH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1713
2,2,2-trichloroethyl
CH2CH═CH2
CN
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1714
2,2,2-trichloroethyl
CH2CH═CH2
CH2C≡CH
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1715
2,2,2-trichloroethyl
CH2CH═CH2
NH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1716
2,2,2-trichloroethyl
CH2CH═CH2
C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1717
2,2,2-trichloroethyl
CH2CH═CH2
C(O)C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1718
2,2,2-trichloroethyl
CH2CH═CH2
C(O)Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1719
2,2,2-trichloroethyl
CH2CH═CH2
S(O)2Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1720
2,2,2-trichloroethyl
CH2CH═CH2
CH2Ph
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1721
2,2,2-trichloroethyl
CH2CH═CH2
CH2(3-Py)
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1722
2,2,2-trichloroethyl
CH2CH═CH2
CH2(3-Py—N-
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3





oxide)


14-1723
2,2,2-trichloroethyl
CN
Et
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1724
2,2,2-trichloroethyl
CN
n-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1725
2,2,2-trichloroethyl
CN
i-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1726
2,2,2-trichloroethyl
CN
CH2CH═CH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1727
2,2,2-trichloroethyl
CN
CN
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1728
2,2,2-trichloroethyl
CN
CH2C≡CH
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1729
2,2,2-trichloroethyl
CN
NH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1730
2,2,2-trichloroethyl
CN
C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1731
2,2,2-trichloroethyl
CN
C(O)C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1732
2,2,2-trichloroethyl
CN
C(O)Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1733
2,2,2-trichloroethyl
CN
S(O)2Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1734
2,2,2-trichloroethyl
CN
CH2Ph
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1735
2,2,2-trichloroethyl
CN
CH2(3-Py)
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1736
2,2,2-trichloroethyl
CN
CH2(3-Py—N-
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3





oxide)


14-1737
2,2,2-trichloroethyl
CH2C≡CH
Et
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1738
2,2,2-trichloroethyl
CH2C≡CH
n-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1739
2,2,2-trichloroethyl
CH2C≡CH
i-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1740
2,2,2-trichloroethyl
CH2C≡CH
CH2CH═CH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1741
2,2,2-trichloroethyl
CH2C≡CH
CN
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1742
2,2,2-trichloroethyl
CH2C≡CH
CH2C≡CH
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1743
2,2,2-trichloroethyl
CH2C≡CH
NH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1744
2,2,2-trichloroethyl
CH2C≡CH
C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1745
2,2,2-trichloroethyl
CH2C≡CH
C(O)C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1746
2,2,2-trichloroethyl
CH2C≡CH
C(O)Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1747
2,2,2-trichloroethyl
CH2C≡CH
S(O)2Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1748
2,2,2-trichloroethyl
CH2C≡CH
CH2Ph
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1749
2,2,2-trichloroethyl
CH2C≡CH
CH2(3-Py)
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1750
2,2,2-trichloroethyl
CH2C≡CH
CH2(3-Py—N-
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3





oxide)


14-1751
2,2,2-trichloroethyl
NH2
Et
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1752
2,2,2-trichloroethyl
NH2
n-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1753
2,2,2-trichloroethyl
NH2
i-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1754
2,2,2-trichloroethyl
NH2
CH2CH═CH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1755
2,2,2-trichloroethyl
NH2
CN
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1756
2,2,2-trichloroethyl
NH2
CH2C≡CH
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1757
2,2,2-trichloroethyl
NH2
NH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1758
2,2,2-trichloroethyl
NH2
C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1759
2,2,2-trichloroethyl
NH2
C(O)C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1760
2,2,2-trichloroethyl
NH2
C(O)Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1761
2,2,2-trichloroethyl
NH2
S(O)2Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1762
2,2,2-trichloroethyl
NH2
CH2Ph
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1763
2,2,2-trichloroethyl
NH2
CH2(3-Py)
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1764
2,2,2-trichloroethyl
NH2
CH2(3-Py—N-
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3





oxide)


14-1765
2,2,2-trichloroethyl
C(O)OMe
Et
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1766
2,2,2-trichloroethyl
C(O)OMe
n-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1767
2,2,2-trichloroethyl
C(O)OMe
i-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1768
2,2,2-trichloroethyl
C(O)OMe
CH2CH═CH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1769
2,2,2-trichloroethyl
C(O)OMe
CN
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1770
2,2,2-trichloroethyl
C(O)OMe
CH2C≡CH
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1771
2,2,2-trichloroethyl
C(O)OMe
NH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1772
2,2,2-trichloroethyl
C(O)OMe
C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1773
2,2,2-trichloroethyl
C(O)OMe
C(O)C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1774
2,2,2-trichloroethyl
C(O)OMe
C(O)Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1775
2,2,2-trichloroethyl
C(O)OMe
S(O)2Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1776
2,2,2-trichloroethyl
C(O)OMe
CH2Ph
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1777
2,2,2-trichloroethyl
C(O)OMe
CH2(3-Py)
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1778
2,2,2-trichloroethyl
C(O)OMe
CH2(3-Py—N-
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3





oxide)


14-1779
2,2,2-trichloroethyl
C(O)C(O)OMe
Et
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1780
2,2,2-trichloroethyl
C(O)C(O)OMe
n-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1781
2,2,2-trichloroethyl
C(O)C(O)OMe
i-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1782
2,2,2-trichloroethyl
C(O)C(O)OMe
CH2CH═CH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1783
2,2,2-trichloroethyl
C(O)C(O)OMe
CN
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1784
2,2,2-trichloroethyl
C(O)C(O)OMe
CH2C≡CH
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1785
2,2,2-trichloroethyl
C(O)C(O)OMe
NH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1786
2,2,2-trichloroethyl
C(O)C(O)OMe
C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1787
2,2,2-trichloroethyl
C(O)C(O)OMe
C(O)C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1788
2,2,2-trichloroethyl
C(O)C(O)OMe
C(O)Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1789
2,2,2-trichloroethyl
C(O)C(O)OMe
S(O)2Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1790
2,2,2-trichloroethyl
C(O)C(O)OMe
CH2Ph
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1791
2,2,2-trichloroethyl
C(O)C(O)OMe
CH2(3-Py)
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1792
2,2,2-trichloroethyl
C(O)C(O)OMe
CH2(3-Py—N-
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3





oxide)


14-1793
2,2,2-trichloroethyl
C(O)Me
Et
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1794
2,2,2-trichloroethyl
C(O)Me
n-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1795
2,2,2-trichloroethyl
C(O)Me
i-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1796
2,2,2-trichloroethyl
C(O)Me
CH2CH═CH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1797
2,2,2-trichloroethyl
C(O)Me
CN
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1798
2,2,2-trichloroethyl
C(O)Me
CH2C≡CH
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1799
2,2,2-trichloroethyl
C(O)Me
NH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1800
2,2,2-trichloroethyl
C(O)Me
C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1801
2,2,2-trichloroethyl
C(O)Me
C(O)C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1802
2,2,2-trichloroethyl
C(O)Me
C(O)Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1803
2,2,2-trichloroethyl
C(O)Me
S(O)2Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1804
2,2,2-trichloroethyl
C(O)Me
CH2Ph
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1805
2,2,2-trichloroethyl
C(O)Me
CH2(3-Py)
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1806
2,2,2-trichloroethyl
C(O)Me
CH2(3-Py—N-
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3





oxide)


14-1807
2,2,2-trichloroethyl
S(O)2Me
Et
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1808
2,2,2-trichloroethyl
S(O)2Me
n-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1809
2,2,2-trichloroethyl
S(O)2Me
i-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1810
2,2,2-trichloroethyl
S(O)2Me
CH2CH 50 CH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1811
2,2,2-trichloroethyl
S(O)2Me
CN
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1812
2,2,2-trichloroethyl
S(O)2Me
CH2C≡CH
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1813
2,2,2-trichloroethyl
S(O)2Me
NH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1814
2,2,2-trichloroethyl
S(O)2Me
C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1815
2,2,2-trichloroethyl
S(O)2Me
C(O)C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1816
2,2,2-trichloroethyl
S(O)2Me
C(O)Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1817
2,2,2-trichloroethyl
S(O)2Me
S(O)2Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1818
2,2,2-trichloroethyl
S(O)2Me
CH2Ph
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1819
2,2,2-trichloroethyl
S(O)2Me
CH2(3-Py)
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1820
2,2,2-trichloroethyl
S(O)2Me
CH2(3-Py—N-
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3





oxide)


14-1821
2,2,2-trichloroethyl
CH2Ph
Et
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1822
2,2,2-trichloroethyl
CH2Ph
n-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1823
2,2,2-trichloroethyl
CH2Ph
i-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1824
2,2,2-trichloroethyl
CH2Ph
CH2CH═CH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1825
2,2,2-trichloroethyl
CH2Ph
CN
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1826
2,2,2-trichloroethyl
CH2Ph
CH2C≡CH
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1827
2,2,2-trichloroethyl
CH2Ph
NH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1828
2,2,2-trichloroethyl
CH2Ph
C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1829
2,2,2-trichloroethyl
CH2Ph
C(O)C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1830
2,2,2-trichloroethyl
CH2Ph
C(O)Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1831
2,2,2-trichloroethyl
CH2Ph
S(O)2Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1832
2,2,2-trichloroethyl
CH2Ph
CH2Ph
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1833
2,2,2-trichloroethyl
CH2Ph
CH2(3-Py)
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1834
2,2,2-trichloroethyl
CH2Ph
CH2(3-Py—N-
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3





oxide)


14-1835
2,2,2-trichloroethyl
CH2(3-Py)
Et
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1836
2,2,2-trichloroethyl
CH2(3-Py)
n-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1837
2,2,2-trichloroethyl
CH2(3-Py)
i-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1838
2,2,2-trichloroethyl
CH2(3-Py)
CH2CH═CH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1839
2,2,2-trichloroethyl
CH2(3-Py)
CN
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1840
2,2,2-trichloroethyl
CH2(3-Py)
CH2C≡CH
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1841
2,2,2-trichloroethyl
CH2(3-Py)
NH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1842
2,2,2-trichloroethyl
CH2(3-Py)
C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1843
2,2,2-trichloroethyl
CH2(3-Py)
C(O)C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1844
2,2,2-trichloroethyl
CH2(3-Py)
C(O)Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1845
2,2,2-trichloroethyl
CH2(3-Py)
S(O)2Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1846
2,2,2-trichloroethyl
CH2(3-Py)
CH2Ph
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1847
2,2,2-trichloroethyl
CH2(3-Py)
CH2(3-Py)
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-1848
2,2,2-trichloroethyl
CH2(3-Py)
CH2(3-Py—N-
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3





oxide)


14-1849
2,2,2-trichloroethyl
CH2(3-Py—N-
Et
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3




oxide)


14-1850
2,2,2-trichloroethyl
CH2(3-Py—N-
n-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3




oxide)


14-1851
2,2,2-trichloroethyl
CH2(3-Py—N-
i-Pr
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3




oxide)


14-1852
2,2,2-trichloroethyl
CH2(3-Py—N-
CH2CH═CH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3




oxide)


14-1853
2,2,2-trichloroethyl
CH2(3-Py—N-
CN
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3




oxide)


14-1854
2,2,2-trichloroethyl
CH2(3-Py—N-
CH2C≡CH
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3




oxide)


14-1855
2,2,2-trichloroethyl
CH2(3-Py—N-
NH2
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3




oxide)


14-1856
2,2,2-trichloroethyl
CH2(3-Py—N-
C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3




oxide)


14-1857
2,2,2-trichloroethyl
CH2(3-Py—N-
C(O)C(O)OMe
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3




oxide)


14-1858
2,2,2-trichloroethyl
CH2(3-Py—N-
C(O)Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3




oxide)


14-1859
2,2,2-trichloroethyl
CH2(3-Py—N-
S(O)2Me
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3




oxide)


14-1860
2,2,2-trichloroethyl
CH2(3-Py—N-
CH2Ph
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3




oxide)


14-1861
2,2,2-trichloroethyl
CH2(3-Py—N-
CH2(3-Py)
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3




oxide)


14-1862
2,2,2-trichloroethyl
CH2(3-Py—N-
CH2(3-Py—N-
F
H
H
H
I
H
nonafluoro-2-butyl
H
CF3




oxide)
oxide)


14-1873
2,2,2-trichloroethyl
Me
Me
F
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


14-1902
2,2,2-trichloroethyl
Me
Me
F
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


14-1931
2,2,2-trichloroethyl
Me
Me
F
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


14-1960
2,2,2-trichloroethyl
Me
Me
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


14-1989
2,2,2-trichloroethyl
Me
Me
F
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


14-2019
2,2,2-trichloroethyl
Me
CH2C≡CH
F
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


14-2233
2,2,2-trichloroethyl
Me
Me
H
F
H
H
F
H
heptafluoroisopropyl
H
F


14-2234
2,2,2-trichloroethyl
Me
Me
H
F
H
H
F
H
nonafluoro-2-butyl
H
F


14-2245
2,2,2-trichloroethyl
Me
Me
H
F
H
H
Cl
H
heptafluoroisopropyl
H
Cl


14-2274
2,2,2-trichloroethyl
Me
Me
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


14-2303
2,2,2-trichloroethyl
Me
Me
H
F
H
H
Br
H
heptafluoroisopropyl
H
Br


14-2332
2,2,2-trichloroethyl
Me
Me
H
F
H
H
Br
H
nonafluoro-2-butyl
H
Br


14-2361
2,2,2-trichloroethyl
Me
Me
H
F
H
H
I
H
heptafluoroisopropyl
H
I


14-2390
2,2,2-trichloroethyl
Me
Me
H
F
H
H
I
H
nonafluoro-2-butyl
H
I


13-1236
2,2,2-trichloroethyl
Me
Me
H
F
H
H
Cl
H
heptafluoroisopropyl
H
Br


14-2605
2,2,2-trichloroethyl
Me
Me
H
F
H
H
F
H
heptafluoroisopropyl
H
OCF3


14-2606
2,2,2-trichloroethyl
Me
Me
H
F
H
H
F
H
nonafluoro-2-butyl
H
OCF3


14-2617
2,2,2-trichloroethyl
Me
Me
H
F
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


14-2646
2,2,2-trichloroethyl
Me
Me
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


14-2675
2,2,2-trichloroethyl
Me
Me
H
F
H
H
Br
H
heptafluoroisopropyl
H
OCF3


14-2704
2,2,2-trichloroethyl
Me
Me
H
F
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


14-2733
2,2,2-trichloroethyl
Me
Me
H
F
H
H
I
H
heptafluoroisopropyl
H
OCF3


14-2762
2,2,2-trichloroethyl
Me
Me
H
F
H
H
I
H
nonafluoro-2-butyl
H
OCF3


14-2977
2,2,2-trichloroethyl
Me
Me
H
F
H
H
F
H
heptafluoroisopropyl
H
CF3


14-2978
2,2,2-trichloroethyl
Me
Me
H
F
H
H
F
H
nonafluoro-2-butyl
H
CF3


14-2989
2,2,2-trichloroethyl
Me
Me
H
F
H
H
Cl
H
heptafluoroisopropyl
H
CF3


14-3018
2,2,2-trichloroethyl
Me
Me
H
F
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


14-3047
2,2,2-trichloroethyl
Me
Me
H
F
H
H
Br
H
heptafluoroisopropyl
H
CF3


14-3076
2,2,2-trichloroethyl
Me
Me
H
F
H
H
Br
H
nonafluoro-2-butyl
H
CF3


14-3105
2,2,2-trichloroethyl
Me
Me
H
F
H
H
I
H
heptafluoroisopropyl
H
CF3


14-3134
2,2,2-trichloroethyl
Me
Me
H
F
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-3359
2,2,2-trichloroethyl
Me
Me
H
F
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


14-3388
2,2,2-trichloroethyl
Me
Me
H
F
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


14-3417
2,2,2-trichloroethyl
Me
Me
H
F
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


14-3446
2,2,2-trichloroethyl
Me
Me
H
F
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


14-3475
2,2,2-trichloroethyl
Me
Me
H
F
H
H
CF3
H
heptafluoroisopropyl
H
CF3


14-3504
2,2,2-trichloroethyl
Me
Me
H
F
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


14-3719
2,2,2-trichloroethyl
Me
Me
F
F
H
H
F
H
heptafluoroisopropyl
H
F


14-3720
2,2,2-trichloroethyl
Me
Me
F
F
H
H
F
H
nonafluoro-2-butyl
H
F


14-3731
2,2,2-trichloroethyl
Me
Me
F
F
H
H
Cl
H
heptafluoroisopropyl
H
Cl


14-3760
2,2,2-trichloroethyl
Me
Me
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


14-3789
2,2,2-trichloroethyl
Me
Me
F
F
H
H
Br
H
heptafluoroisopropyl
H
Br


14-3818
2,2,2-trichloroethyl
Me
Me
F
F
H
H
Br
H
nonafluoro-2-butyl
H
Br


14-3847
2,2,2-trichloroethyl
Me
Me
F
F
H
H
I
H
heptafluoroisopropyl
H
I


14-3876
2,2,2-trichloroethyl
Me
Me
F
F
H
H
I
H
nonafluoro-2-butyl
H
I


13-1950
2,2,2-trichloroethyl
Me
Me
F
F
H
H
Cl
H
heptafluoroisopropyl
H
Br


14-4091
2,2,2-trichloroethyl
Me
Me
F
F
H
H
F
H
heptafluoroisopropyl
H
OCF3


14-4092
2,2,2-trichloroethyl
Me
Me
F
F
H
H
F
H
nonafluoro-2-butyl
H
OCF3


14-4103
2,2,2-trichloroethyl
Me
Me
F
F
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


14-4132
2,2,2-trichloroethyl
Me
Me
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


14-4161
2,2,2-trichloroethyl
Me
Me
F
F
H
H
Br
H
heptafluoroisopropyl
H
OCF3


14-4190
2,2,2-trichloroethyl
Me
Me
F
F
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


14-4219
2,2,2-trichloroethyl
Me
Me
F
F
H
H
I
H
heptafluoroisopropyl
H
OCF3


14-4248
2,2,2-trichloroethyl
Me
Me
F
F
H
H
I
H
nonafluoro-2-butyl
H
OCF3


14-4463
2,2,2-trichloroethyl
Me
Me
F
F
H
H
F
H
heptafluoroisopropyl
H
CF3


14-4464
2,2,2-trichloroethyl
Me
Me
F
F
H
H
F
H
nonafluoro-2-butyl
H
CF3


14-4475
2,2,2-trichloroethyl
Me
Me
F
F
H
H
Cl
H
heptafluoroisopropyl
H
CF3


14-4504
2,2,2-trichloroethyl
Me
Me
F
F
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


14-4533
2,2,2-trichloroethyl
Me
Me
F
F
H
H
Br
H
heptafluoroisopropyl
H
CF3


14-4562
2,2,2-trichloroethyl
Me
Me
F
F
H
H
Br
H
nonafluoro-2-butyl
H
CF3


14-4591
2,2,2-trichloroethyl
Me
Me
F
F
H
H
I
H
heptafluoroisopropyl
H
CF3


14-4620
2,2,2-trichloroethyl
Me
Me
F
F
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-4845
2,2,2-trichloroethyl
Me
Me
F
F
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


14-4874
2,2,2-trichloroethyl
Me
Me
F
F
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


14-4903
2,2,2-trichloroethyl
Me
Me
F
F
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


14-4932
2,2,2-trichloroethyl
Me
Me
F
F
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


14-4961
2,2,2-trichloroethyl
Me
Me
F
F
H
H
CF3
H
heptafluoroisopropyl
H
CF3


14-4990
2,2,2-trichloroethyl
Me
Me
F
F
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


14-5205
2,2,2-trichloroethyl
Me
Me
F
F
F
H
Cl
H
pentafluoroethyl
H
Cl


14-5206
2,2,2-trichloroethyl
Me
Me
F
F
F
H
Br
H
heptafluoroisopropyl
H
Br


14-5207
2,2,2-trichloroethyl
Me
Me
F
F
F
H
Br
H
heptafluoroisopropyl
H
OCF3


14-5208
2,2,2-trichloroethyl
Me
Me
F
F
F
H
I
H
heptafluoroisopropyl
H
CF3


14-5209
2,2,2-trichloroethyl
Me
Me
F
F
F
H
CF3
H
heptafluoroisopropyl
H
CF3


14-5210
2,2,2-trichloroethyl
Me
Me
F
F
F
H
I
H
nonafluoro-2-butyl
H
I


14-5211
2,2,2-trichloroethyl
Me
Me
F
F
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


14-5212
2,2,2-trichloroethyl
Me
Me
F
F
F
H
Br
H
nonafluoro-2-butyl
H
CF3


14-5213
2,2,2-trichloroethyl
Me
Me
F
F
F
H
CF3
H
nonafluoro-2-butyl
H
CF3


14-5214
2,2,2-trichloroethyl
Me
Me
H
H
F
H
Cl
H
pentafluoroethyl
H
Cl


14-5215
2,2,2-trichloroethyl
Me
Me
H
H
F
H
Br
H
heptafluoroisopropyl
H
Br


14-5216
2,2,2-trichloroethyl
Me
Me
H
H
F
H
Br
H
heptafluoroisopropyl
H
OCF3


14-5217
2,2,2-trichloroethyl
Me
Me
H
H
F
H
I
H
heptafluoroisopropyl
H
CF3


14-5218
2,2,2-trichloroethyl
Me
Me
H
H
F
H
CF3
H
heptafluoroisopropyl
H
CF3


14-5219
2,2,2-trichloroethyl
Me
Me
H
H
F
H
I
H
nonafluoro-2-butyl
H
I


14-5220
2,2,2-trichloroethyl
Me
Me
H
H
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


14-5221
2,2,2-trichloroethyl
Me
Me
H
H
F
H
Br
H
nonafluoro-2-butyl
H
CF3


14-5222
2,2,2-trichloroethyl
Me
Me
H
H
F
H
CF3
H
nonafluoro-2-butyl
H
CF3


14-5223
2,2,2-trichloroethyl
Me
Me
H
H
H
F
Cl
H
pentafluoroethyl
H
Cl


14-5224
2,2,2-trichloroethyl
Me
Me
H
H
H
F
Br
H
heptafluoroisopropyl
H
Br


14-5225
2,2,2-trichloroethyl
Me
Me
H
H
H
F
Br
H
heptafluoroisopropyl
H
OCF3


14-5226
2,2,2-trichloroethyl
Me
Me
H
H
H
F
I
H
heptafluoroisopropyl
H
CF3


14-5227
2,2,2-trichloroethyl
Me
Me
H
H
H
F
CF3
H
heptafluoroisopropyl
H
CF3


14-5228
2,2,2-trichloroethyl
Me
Me
H
H
H
F
I
H
nonafluoro-2-butyl
H
I


14-5229
2,2,2-trichloroethyl
Me
Me
H
H
H
F
Cl
H
nonafluoro-2-butyl
H
OCF3


14-5230
2,2,2-trichloroethyl
Me
Me
H
H
H
F
Br
H
nonafluoro-2-butyl
H
CF3


14-5231
2,2,2-trichloroethyl
Me
Me
H
H
H
F
CF3
H
nonafluoro-2-butyl
H
CF3


14-5232
2,2,2-trichloroethyl
Me
Me
F
H
F
H
Cl
H
pentafluoroethyl
H
Cl


14-5233
2,2,2-trichloroethyl
Me
Me
F
H
F
H
Br
H
heptafluoroisopropyl
H
Br


14-5234
2,2,2-trichloroethyl
Me
Me
F
H
F
H
Br
H
heptafluoroisopropyl
H
OCF3


14-5235
2,2,2-trichloroethyl
Me
Me
F
H
F
H
I
H
heptafluoroisopropyl
H
CF3


14-5236
2,2,2-trichloroethyl
Me
Me
F
H
F
H
CF3
H
heptafluoroisopropyl
H
CF3


14-5237
2,2,2-trichloroethyl
Me
Me
F
H
F
H
I
H
nonafluoro-2-butyl
H
I


14-5238
2,2,2-trichloroethyl
Me
Me
F
H
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


14-5239
2,2,2-trichloroethyl
Me
Me
F
H
F
H
Br
H
nonafluoro-2-butyl
H
CF3


14-5240
2,2,2-trichloroethyl
Me
Me
F
H
F
H
CF3
H
nonafluoro-2-butyl
H
CF3


14-5241
2,2,2-trichloroethyl
Me
Me
F
H
H
F
Cl
H
pentafluoroethyl
H
Cl


14-5242
2,2,2-trichloroethyl
Me
Me
F
H
H
F
Br
H
heptafluoroisopropyl
H
Br


14-5243
2,2,2-trichloroethyl
Me
Me
F
H
H
F
Br
H
heptafluoroisopropyl
H
OCF3


14-5244
2,2,2-trichloroethyl
Me
Me
F
H
H
F
I
H
heptafluoroisopropyl
H
CF3


14-5245
2,2,2-trichloroethyl
Me
Me
F
H
H
F
CF3
H
heptafluoroisopropyl
H
CF3


14-5246
2,2,2-trichloroethyl
Me
Me
F
H
H
F
I
H
nonafluoro-2-butyl
H
I


14-5247
2,2,2-trichloroethyl
Me
Me
F
H
H
F
Cl
H
nonafluoro-2-butyl
H
OCF3


14-5248
2,2,2-trichloroethyl
Me
Me
F
H
H
F
Br
H
nonafluoro-2-butyl
H
CF3


14-5249
2,2,2-trichloroethyl
Me
Me
F
H
H
F
CF3
H
nonafluoro-2-butyl
H
CF3


14-5250
2,2,2-trichloroethyl
Me
Me
H
F
F
H
Cl
H
pentafluoroethyl
H
Cl


14-5251
2,2,2-trichloroethyl
Me
Me
H
F
F
H
Br
H
heptafluoroisopropyl
H
Br


14-5252
2,2,2-trichloroethyl
Me
Me
H
F
F
H
Br
H
heptafluoroisopropyl
H
OCF3


14-5253
2,2,2-trichloroethyl
Me
Me
H
F
F
H
I
H
heptafluoroisopropyl
H
CF3


14-5254
2,2,2-trichloroethyl
Me
Me
H
F
F
H
CF3
H
heptafluoroisopropyl
H
CF3


14-5255
2,2,2-trichloroethyl
Me
Me
H
F
F
H
I
H
nonafluoro-2-butyl
H
I


14-5256
2,2,2-trichloroethyl
Me
Me
H
F
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


14-5257
2,2,2-trichloroethyl
Me
Me
H
F
F
H
Br
H
nonafluoro-2-butyl
H
CF3


14-5258
2,2,2-trichloroethyl
Me
Me
H
F
F
H
CF3
H
nonafluoro-2-butyl
H
CF3


14-5259
2,2,2-trichloroethyl
Me
Me
H
F
H
F
Cl
H
pentafluoroethyl
H
Cl


14-5260
2,2,2-trichloroethyl
Me
Me
H
F
H
F
Br
H
heptafluoroisopropyl
H
Br


14-5261
2,2,2-trichloroethyl
Me
Me
H
F
H
F
Br
H
heptafluoroisopropyl
H
OCF3


14-5262
2,2,2-trichloroethyl
Me
Me
H
F
H
F
I
H
heptafluoroisopropyl
H
CF3


14-5263
2,2,2-trichloroethyl
Me
Me
H
F
H
F
CF3
H
heptafluoroisopropyl
H
CF3


14-5264
2,2,2-trichloroethyl
Me
Me
H
F
H
F
I
H
nonafluoro-2-butyl
H
I


14-5265
2,2,2-trichloroethyl
Me
Me
H
F
H
F
Cl
H
nonafluoro-2-butyl
H
OCF3


14-5266
2,2,2-trichloroethyl
Me
Me
H
F
H
F
Br
H
nonafluoro-2-butyl
H
CF3


14-5267
2,2,2-trichloroethyl
Me
Me
H
F
H
F
CF3
H
nonafluoro-2-butyl
H
CF3


14-5268
2,2,2-trichloroethyl
Me
Me
H
H
F
F
Cl
H
pentafluoroethyl
H
Cl


14-5269
2,2,2-trichloroethyl
Me
Me
H
H
F
F
Br
H
heptafluoroisopropyl
H
Br


14-5270
2,2,2-trichloroethyl
Me
Me
H
H
F
F
Br
H
heptafluoroisopropyl
H
OCF3


14-5271
2,2,2-trichloroethyl
Me
Me
H
H
F
F
I
H
heptafluoroisopropyl
H
CF3


14-5272
2,2,2-trichloroethyl
Me
Me
H
H
F
F
CF3
H
heptafluoroisopropyl
H
CF3


14-5273
2,2,2-trichloroethyl
Me
Me
H
H
F
F
I
H
nonafluoro-2-butyl
H
I


14-5274
2,2,2-trichloroethyl
Me
Me
H
H
F
F
Cl
H
nonafluoro-2-butyl
H
OCF3


14-5275
2,2,2-trichloroethyl
Me
Me
H
H
F
F
Br
H
nonafluoro-2-butyl
H
CF3


14-5276
2,2,2-trichloroethyl
Me
Me
H
H
F
F
CF3
H
nonafluoro-2-butyl
H
CF3


14-5277
2,2,2-trichloroethyl
Me
Me
F
F
H
F
Cl
H
pentafluoroethyl
H
Cl


14-5278
2,2,2-trichloroethyl
Me
Me
F
F
H
F
Br
H
heptafluoroisopropyl
H
Br


14-5279
2,2,2-trichloroethyl
Me
Me
F
F
H
F
Br
H
heptafluoroisopropyl
H
OCF3


14-5280
2,2,2-trichloroethyl
Me
Me
F
F
H
F
I
H
heptafluoroisopropyl
H
CF3


14-5281
2,2,2-trichloroethyl
Me
Me
F
F
H
F
CF3
H
heptafluoroisopropyl
H
CF3


14-5282
2,2,2-trichloroethyl
Me
Me
F
F
H
F
I
H
nonafluoro-2-butyl
H
I


14-5283
2,2,2-trichloroethyl
Me
Me
F
F
H
F
Cl
H
nonafluoro-2-butyl
H
OCF3


14-5284
2,2,2-trichloroethyl
Me
Me
F
F
H
F
Br
H
nonafluoro-2-butyl
H
CF3


14-5285
2,2,2-trichloroethyl
Me
Me
F
F
H
F
CF3
H
nonafluoro-2-butyl
H
CF3


14-5286
2,2,2-trichloroethyl
Me
Me
F
H
F
F
Cl
H
pentafluoroethyl
H
Cl


14-5287
2,2,2-trichloroethyl
Me
Me
F
H
F
F
Br
H
heptafluoroisopropyl
H
Br


14-5288
2,2,2-trichloroethyl
Me
Me
F
H
F
F
Br
H
heptafluoroisopropyl
H
OCF3


14-5289
2,2,2-trichloroethyl
Me
Me
F
H
F
F
I
H
heptafluoroisopropyl
H
CF3


14-5290
2,2,2-trichloroethyl
Me
Me
F
H
F
F
CF3
H
heptafluoroisopropyl
H
CF3


14-5291
2,2,2-trichloroethyl
Me
Me
F
H
F
F
I
H
nonafluoro-2-butyl
H
I


14-5292
2,2,2-trichloroethyl
Me
Me
F
H
F
F
Cl
H
nonafluoro-2-butyl
H
OCF3


14-5293
2,2,2-trichloroethyl
Me
Me
F
H
F
F
Br
H
nonafluoro-2-butyl
H
CF3


14-5294
2,2,2-trichloroethyl
Me
Me
F
H
F
F
CF3
H
nonafluoro-2-butyl
H
CF3


14-5295
2,2,2-trichloroethyl
Me
Me
H
F
F
F
Cl
H
pentafluoroethyl
H
Cl


14-5296
2,2,2-trichloroethyl
Me
Me
H
F
F
F
Br
H
heptafluoroisopropyl
H
Br


14-5297
2,2,2-trichloroethyl
Me
Me
H
F
F
F
Br
H
heptafluoroisopropyl
H
OCF3


14-5298
2,2,2-trichloroethyl
Me
Me
H
F
F
F
I
H
heptafluoroisopropyl
H
CF3


14-5299
2,2,2-trichloroethyl
Me
Me
H
F
F
F
CF3
H
heptafluoroisopropyl
H
CF3


14-5300
2,2,2-trichloroethyl
Me
Me
H
F
F
F
I
H
nonafluoro-2-butyl
H
I


14-5301
2,2,2-trichloroethyl
Me
Me
H
F
F
F
Cl
H
nonafluoro-2-butyl
H
OCF3


14-5302
2,2,2-trichloroethyl
Me
Me
H
F
F
F
Br
H
nonafluoro-2-butyl
H
CF3


14-5303
2,2,2-trichloroethyl
Me
Me
H
F
F
F
CF3
H
nonafluoro-2-butyl
H
CF3


14-5304
2,2,2-trichloroethyl
Me
Me
F
F
F
F
Cl
H
pentafluoroethyl
H
Cl


14-5305
2,2,2-trichloroethyl
Me
Me
F
F
F
F
Br
H
heptafluoroisopropyl
H
Br


14-5306
2,2,2-trichloroethyl
Me
Me
F
F
F
F
Br
H
heptafluoroisopropyl
H
OCF3


14-5307
2,2,2-trichloroethyl
Me
Me
F
F
F
F
I
H
heptafluoroisopropyl
H
CF3


14-5308
2,2,2-trichloroethyl
Me
Me
F
F
F
F
CF3
H
heptafluoroisopropyl
H
CF3


14-5309
2,2,2-trichloroethyl
Me
Me
F
F
F
F
I
H
nonafluoro-2-butyl
H
I


14-5310
2,2,2-trichloroethyl
Me
Me
F
F
F
F
Cl
H
nonafluoro-2-butyl
H
OCF3


14-5311
2,2,2-trichloroethyl
Me
Me
F
F
F
F
Br
H
nonafluoro-2-butyl
H
CF3


14-5312
2,2,2-trichloroethyl
Me
Me
F
F
F
F
CF3
H
nonafluoro-2-butyl
H
CF3


14-5313
2,2,2-trichloroethyl
Me
Me
H
CN
H
H
F
H
heptafluoroisopropyl
H
OCF3


14-5314
2,2,2-trichloroethyl
Me
Me
H
CN
H
H
F
H
nonafluoro-2-butyl
H
OCF3


14-5325
2,2,2-trichloroethyl
Me
Me
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


14-5354
2,2,2-trichloroethyl
Me
Me
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


14-5383
2,2,2-trichloroethyl
Me
Me
H
CN
H
H
Br
H
heptafluoroisopropyl
H
OCF3


14-5412
2,2,2-trichloroethyl
Me
Me
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


14-5441
2,2,2-trichloroethyl
Me
Me
H
CN
H
H
I
H
heptafluoroisopropyl
H
OCF3


14-5470
2,2,2-trichloroethyl
Me
Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
OCF3


14-5685
2,2,2-trichloroethyl
Me
Me
H
CN
H
H
F
H
heptafluoroisopropyl
H
CF3


14-5686
2,2,2-trichloroethyl
Me
Me
H
CN
H
H
F
H
nonafluoro-2-butyl
H
CF3


14-5697
2,2,2-trichloroethyl
Me
Me
H
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


14-5726
2,2,2-trichloroethyl
Me
Me
H
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


14-5755
2,2,2-trichloroethyl
Me
Me
H
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


14-5784
2,2,2-trichloroethyl
Me
Me
H
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


14-5813
2,2,2-trichloroethyl
Me
Me
H
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


14-5842
2,2,2-trichloroethyl
Me
Me
H
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-6067
2,2,2-trichloroethyl
Me
Me
H
CN
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


14-6096
2,2,2-trichloroethyl
Me
Me
H
CN
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


14-6125
2,2,2-trichloroethyl
Me
Me
H
CN
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


14-6154
2,2,2-trichloroethyl
Me
Me
H
CN
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


14-6183
2,2,2-trichloroethyl
Me
Me
H
CN
H
H
CF3
H
heptafluoroisopropyl
H
CF3


14-6212
2,2,2-trichloroethyl
Me
Me
H
CN
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


14-6427
2,2,2-trichloroethyl
Me
Me
F
CN
H
H
F
H
heptafluoroisopropyl
H
F


14-6428
2,2,2-trichloroethyl
Me
Me
F
CN
H
H
F
H
nonafluoro-2-butyl
H
F


14-6439
2,2,2-trichloroethyl
Me
Me
F
CN
H
H
Cl
H
heptafluoroisopropyl
H
Cl


14-6468
2,2,2-trichloroethyl
Me
Me
F
CN
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


14-6497
2,2,2-trichloroethyl
Me
Me
F
CN
H
H
Br
H
heptafluoroisopropyl
H
Br


14-6526
2,2,2-trichloroethyl
Me
Me
F
CN
H
H
Br
H
nonafluoro-2-butyl
H
Br


14-6555
2,2,2-trichloroethyl
Me
Me
F
CN
H
H
I
H
heptafluoroisopropyl
H
I


14-6584
2,2,2-trichloroethyl
Me
Me
F
CN
H
H
I
H
nonafluoro-2-butyl
H
I


13-3306
2,2,2-trichloroethyl
Me
Me
F
CN
H
H
Br
H
nonafluoro-2-butyl
H
I


14-6799
2,2,2-trichloroethyl
Me
Me
F
CN
H
H
F
H
heptafluoroisopropyl
H
OCF3


14-6800
2,2,2-trichloroethyl
Me
Me
F
CN
H
H
F
H
nonafluoro-2-butyl
H
OCF3


14-6811
2,2,2-trichloroethyl
Me
Me
F
CN
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


14-6840
2,2,2-trichloroethyl
Me
Me
F
CN
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


14-6869
2,2,2-trichloroethyl
Me
Me
F
CN
H
H
Br
H
heptafluoroisopropyl
H
OCF3


14-6898
2,2,2-trichloroethyl
Me
Me
F
CN
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


14-6927
2,2,2-trichloroethyl
Me
Me
F
CN
H
H
I
H
heptafluoroisopropyl
H
OCF3


14-6956
2,2,2-trichloroethyl
Me
Me
F
CN
H
H
I
H
nonafluoro-2-butyl
H
OCF3


14-7171
2,2,2-trichloroethyl
Me
Me
F
CN
H
H
F
H
heptafluoroisopropyl
H
CF3


14-7172
2,2,2-trichloroethyl
Me
Me
F
CN
H
H
F
H
nonafluoro-2-butyl
H
CF3


14-7183
2,2,2-trichloroethyl
Me
Me
F
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


14-7212
2,2,2-trichloroethyl
Me
Me
F
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


14-7241
2,2,2-trichloroethyl
Me
Me
F
CN
H
H
Br
H
heptafluoroisopropyl
H
CF3


14-7270
2,2,2-trichloroethyl
Me
Me
F
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


14-7299
2,2,2-trichloroethyl
Me
Me
F
CN
H
H
I
H
heptafluoroisopropyl
H
CF3


14-7328
2,2,2-trichloroethyl
Me
Me
F
CN
H
H
I
H
nonafluoro-2-butyl
H
CF3


14-7553
2,2,2-trichloroethyl
Me
Me
F
CN
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


14-7582
2,2,2-trichloroethyl
Me
Me
F
CN
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


14-7611
2,2,2-trichloroethyl
Me
Me
F
CN
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


14-7640
2,2,2-trichloroethyl
Me
Me
F
CN
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


14-7669
2,2,2-trichloroethyl
Me
Me
F
CN
H
H
CF3
H
heptafluoroisopropyl
H
CF3


14-7698
2,2,2-trichloroethyl
Me
Me
F
CN
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


14-7913
2,2,2-trichloroethyl
Me
Me
F
CN
F
H
F
H
heptafluoroisopropyl
H
F


14-7914
2,2,2-trichloroethyl
Me
Me
F
CN
F
H
F
H
nonafluoro-2-butyl
H
F


14-7925
2,2,2-trichloroethyl
Me
Me
F
CN
F
H
Cl
H
heptafluoroisopropyl
H
Cl


14-7954
2,2,2-trichloroethyl
Me
Me
F
CN
F
H
Cl
H
nonafluoro-2-butyl
H
Cl


14-7983
2,2,2-trichloroethyl
Me
Me
F
CN
F
H
Br
H
heptafluoroisopropyl
H
Br


14-8012
2,2,2-trichloroethyl
Me
Me
F
CN
F
H
Br
H
nonafluoro-2-butyl
H
Br


14-8041
2,2,2-trichloroethyl
Me
Me
F
CN
F
H
I
H
heptafluoroisopropyl
H
I


14-8070
2,2,2-trichloroethyl
Me
Me
F
CN
F
H
I
H
nonafluoro-2-butyl
H
I


13-4012
2,2,2-trichloroethyl
Me
Me
F
CN
F
H
Cl
H
heptafluoroisopropyl
H
Br


14-8285
2,2,2-trichloroethyl
Me
Me
F
CN
F
H
F
H
heptafluoroisopropyl
H
OCF3


14-8286
2,2,2-trichloroethyl
Me
Me
F
CN
F
H
F
H
nonafluoro-2-butyl
H
OCF3


14-8297
2,2,2-trichloroethyl
Me
Me
F
CN
F
H
Cl
H
heptafluoroisopropyl
H
OCF3


14-8326
2,2,2-trichloroethyl
Me
Me
F
CN
F
H
Cl
H
nonafluoro-2-butyl
H
OCF3


14-8355
2,2,2-trichloroethyl
Me
Me
F
CN
F
H
Br
H
heptafluoroisopropyl
H
OCF3


14-8384
2,2,2-trichloroethyl
Me
Me
F
CN
F
H
Br
H
nonafluoro-2-butyl
H
OCF3


14-8413
2,2,2-trichloroethyl
Me
Me
F
CN
F
H
I
H
heptafluoroisopropyl
H
OCF3


14-8442
2,2,2-trichloroethyl
Me
Me
F
CN
F
H
I
H
nonafluoro-2-butyl
H
OCF3


14-8657
2,2,2-trichloroethyl
Me
Me
F
CN
F
H
F
H
heptafluoroisopropyl
H
CF3


14-8658
2,2,2-trichloroethyl
Me
Me
F
CN
F
H
F
H
nonafluoro-2-butyl
H
CF3


14-8669
2,2,2-trichloroethyl
Me
Me
F
CN
F
H
Cl
H
heptafluoroisopropyl
H
CF3


14-8698
2,2,2-trichloroethyl
Me
Me
F
CN
F
H
Cl
H
nonafluoro-2-butyl
H
CF3


14-8727
2,2,2-trichloroethyl
Me
Me
F
CN
F
H
Br
H
heptafluoroisopropyl
H
CF3


14-8756
2,2,2-trichloroethyl
Me
Me
F
CN
F
H
Br
H
nonafluoro-2-butyl
H
CF3


14-8785
2,2,2-trichloroethyl
Me
Me
F
CN
F
H
I
H
heptafluoroisopropyl
H
CF3


14-8814
2,2,2-trichloroethyl
Me
Me
F
CN
F
H
I
H
nonafluoro-2-butyl
H
CF3


14-9039
2,2,2-trichloroethyl
Me
Me
F
CN
F
H
OCF3
H
heptafluoroisopropyl
H
OCF3


14-9068
2,2,2-trichloroethyl
Me
Me
F
CN
F
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


14-9097
2,2,2-trichloroethyl
Me
Me
F
CN
F
H
CF3
H
heptafluoroisopropyl
H
OCF3


14-9126
2,2,2-trichloroethyl
Me
Me
F
CN
F
H
CF3
H
nonafluoro-2-butyl
H
OCF3


14-9155
2,2,2-trichloroethyl
Me
Me
F
CN
F
H
CF3
H
heptafluoroisopropyl
H
CF3


14-9184
2,2,2-trichloroethyl
Me
Me
F
CN
F
H
CF3
H
nonafluoro-2-butyl
H
CF3











embedded image





















TABLE 15





compound














number
Q2
R1
R2
X1
X2
X3
X4
Y1
Y2
Y3
Y4
Y5







15-9
2,2-dichloroethyl
H
Et
H
H
H
H
Cl
F
heptafluoroisopropyl
F
OCF3


15-39
2,2,2-trifluoroethyl
H
H
H
H
H
H
Cl
Me
nonafluoro-2-butyl
Me
OCF3


15-144
methyl
H
H
H
H
H
H
Cl
F
heptafluoroisopropyl
H
CF3


15-147
2-chloroethyl
Me
Me
H
H
H
H
Cl
H
heptafluoroisopropyl
Cl
CF3


15-148
2-bromoethyl
H
H
H
H
H
H
F
Br
heptafluoroisopropyl
H
CF3


15-153
2,2,2-trifluoroethyl
H
H
H
H
H
H
Cl
F
heptafluoroisopropyl
Cl
CF3


15-165
3,3,3-trifluoro-n-propyl
H
H
H
H
H
H
Cl
I
nonafluoro-2-butyl
Cl
CF3


15-168
i-butyl
H
H
H
H
H
H
Cl
Me
nonafluoro-2-butyl
H
CF3


15-169
s-butyl
H
H
H
H
H
H
Cl
H
nonafluoro-2-butyl
Me
CF3


15-170
vinyl
i-Pr
H
H
H
H
H
Cl
Et
nonafluoro-2-butyl
H
CF3


15-171
benzyl
H
H
H
H
H
H
Cl
H
nonafluoro-2-butyl
Et
CF3


15-182
2,2,2-trifluoroethyl
H
H
H
H
H
H
Cl
Me
nonafluoro-2-butyl
Me
n-C3F7


15-183
2,2,2-trichloroethyl
H
H
H
H
H
H
Cl
Me
nonafluoro-2-butyl
Et
i-C3F7


15-189
i-propyl
H
H
H
H
H
H
Cl
Et
nonafluoro-2-butyl
Me
n-C3F7


15-190
1,2-difluoro-2-propyl
H
H
H
H
H
H
Cl
Et
nonafluoro-2-butyl
Et
i-C3F7


15-196
2-chloroethyl
H
H
H
H
H
H
Br
n-Pr
heptafluoroisopropyl
Me
CF3


15-197
2-bromoethyl
H
H
H
H
H
H
Br
n-Pr
heptafluoroisopropyl
Et
CF3


15-203
2,2,2-trichloroethyl
H
H
H
H
H
H
Br
i-Pr
heptafluoroisopropyl
Me
CF3


15-204
2,2,2-tribromoethyl
H
H
H
H
H
H
Br
i-Pr
heptafluoroisopropyl
Et
CF3


15-210
1,2-difluoro-2-propyl
H
H
H
H
H
H
Br
n-Bu
heptafluoroisopropyl
Me
CF3


15-211
1,3-difluoro-2-propyl
H
H
H
H
H
H
Br
n-Bu
heptafluoroisopropyl
Et
CF3


15-217
i-butyl
H
H
H
H
H
H
Br
i-Bu
nonafluoro-2-butyl
Me
CF3


15-218
s-butyl
H
H
H
H
H
H
Br
i-Bu
nonafluoro-2-butyl
Et
CF3


15-224
2-fluoroethyl
H
H
H
H
H
H
Br
s-Bu
nonafluoro-2-butyl
Me
CF3


15-225
2-chloroethyl
H
H
H
H
H
H
Br
s-Bu
nonafluoro-2-butyl
Et
CF3


15-231
2,2,2-trifluoroethyl
H
H
H
H
H
H
Br
F
nonafluoro-2-butyl
Me
CF3


15-232
2,2,2-trichloroethyl
H
H
H
H
H
H
Br
F
nonafluoro-2-butyl
Et
CF3


15-238
i-propyl
Et
i-Pr
H
H
H
H
Br
Cl
nonafluoro-2-butyl
Me
CF3


15-239
1,2-difluoro-2-propyl
H
H
H
H
H
H
Br
Cl
nonafluoro-2-butyl
Et
CF3


15-245
2-iodoethyl
H
H
H
H
H
H
I
Br
heptafluoroisopropyl
Me
CF3


15-246
2-cyanoethyl
H
H
H
H
H
H
I
Br
heptafluoroisopropyl
Et
CF3


15-252
n-propyl
n-Pr
Me
H
H
H
H
I
I
heptafluoroisopropyl
Me
CF3


15-253
3-fluoro-n-propyl
H
H
H
H
H
H
I
I
heptafluoroisopropyl
Et
CF3


15-259
1,3-dichloro-2-propyl
H
H
H
H
H
H
I
Me
heptafluoroisopropyl
F
C2F5


15-260
1-chloro-3-fluoro-2-propyl
H
H
H
H
H
H
I
Me
nonafluoro-2-butyl
Cl
CF3


15-263
4,4,4-trifluoro-n-butyl
H
H
H
H
H
H
I
Et
nonafluoro-2-butyl
F
CF3


15-264
i-butyl
H
H
H
H
H
H
I
Et
nonafluoro-2-butyl
Cl
CF3


15-267
benzyl
H
H
H
H
H
H
I
n-Pr
nonafluoro-2-butyl
F
CF3


15-268
phenyl
H
H
H
H
H
H
I
n-Pr
nonafluoro-2-butyl
Cl
CF3


15-271
2-fluoroethyl
H
H
H
H
H
H
I
i-Pr
nonafluoro-2-butyl
F
i-C3F7


15-272
2-chloroethyl
H
H
H
H
H
H
I
i-Pr
nonafluoro-2-butyl
Cl
CF3


15-275
2-cyanoethyl
H
H
H
H
H
H
I
n-Bu
nonafluoro-2-butyl
F
CF3


15-276
2,2-difluoroethyl
H
H
H
H
H
H
I
n-Bu
nonafluoro-2-butyl
Cl
CF3


15-279
2,2,2-trichloroethyl
H
H
H
H
H
H
I
i-Bu
nonafluoro-2-butyl
F
CF3


15-280
2,2,2-tribromoethyl
H
H
H
H
H
H
I
i-Bu
nonafluoro-2-butyl
Cl
CF3


15-283
3-chloro-n-propyl
i-Pr
n-Pr
H
H
H
H
I
s-Bu
nonafluoro-2-butyl
F
CF3


15-284
3-bromo-n-propyl
H
H
H
H
H
H
I
s-Bu
nonafluoro-2-butyl
Cl
CF3


15-295
2,2-dichloroethyl
H
Et
H
H
H
H
OCF3
F
heptafluoroisopropyl
F
OCF3


15-325
2,2,2-trifluoroethyl
H
H
H
H
H
H
OCF3
Me
nonafluoro-2-butyl
Me
OCF3


15-438
2,2-dichloroethyl
H
Et
H
H
H
H
OCF3
F
heptafluoroisopropyl
F
CF3


15-468
2,2,2-trifluoroethyl
H
H
H
H
H
H
OCF3
Me
nonafluoro-2-butyl
Me
CF3


15-581
2,2-dichloroethyl
H
Et
H
H
H
H
CF3
F
heptafluoroisopropyl
F
CF3


15-611
2,2,2-trifluoroethyl
H
H
H
H
H
H
CF3
Me
nonafluoro-2-butyl
Me
CF3


15-734
2,2-dichloroethyl
H
Et
F
H
H
H
Cl
F
heptafluoroisopropyl
F
OCF3


15-764
2,2,2-trifluoroethyl
H
H
F
H
H
H
Cl
Me
nonafluoro-2-butyl
Me
OCF3


15-869
methyl
H
H
F
H
H
H
Cl
F
heptafluoroisopropyl
H
CF3


15-870
ethyl
Me
H
F
H
H
H
Cl
H
heptafluoroisopropyl
F
CF3


15-871
2-fluoroethyl
H
Me
F
H
H
H
Cl
Cl
heptafluoroisopropyl
H
CF3


15-872
2-chloroethyl
Me
Me
F
H
H
H
Cl
H
heptafluoroisopropyl
Cl
CF3


15-873
2-bromoethyl
H
H
F
H
H
H
F
Br
heptafluoroisopropyl
H
CF3


15-874
2-iodoethyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
Br
CF3


15-875
2-cyanoethyl
Et
H
F
H
H
H
Cl
I
heptafluoroisopropyl
H
C2F5


15-876
2,2-difluoroethyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
I
CF3


15-877
2,2-dichloroethyl
H
Et
F
H
H
H
Cl
F
heptafluoroisopropyl
F
CF3


15-878
2,2,2-trifluoroethyl
H
H
F
H
H
H
Cl
F
heptafluoroisopropyl
Cl
CF3


15-879
2,2,2-trichloroethyl
H
H
F
H
H
H
Cl
F
heptafluoroisopropyl
Br
CF3


15-880
2,2,2-tribromoethyl
Et
Et
F
H
H
H
Cl
F
pentafluoroethyl
I
C2F5


15-881
n-propyl
H
H
F
H
H
H
Cl
Cl
pentafluoroethyl
F
CF3


15-882
3-fluoro-n-propyl
H
H
F
H
H
H
Cl
Cl
heptafluoroisopropyl
Cl
CF3


15-883
3-chloro-n-propyl
n-Pr
H
F
H
H
H
Cl
Cl
heptafluoroisopropyl
Br
CF3


15-884
3-bromo-n-propyl
H
H
F
H
H
H
Cl
Cl
heptafluoroisopropyl
I
n-C3F7


15-885
i-propyl
H
n-Pr
F
H
H
H
Cl
Br
heptafluoroisopropyl
F
CF3


15-886
1,2-difluoro-2-propyl
H
H
F
H
H
H
Cl
Br
heptafluoroisopropyl
Cl
CF3


15-887
1,3-difluoro-2-propyl
H
H
F
H
H
H
Cl
Br
heptafluoroisopropyl
Br
CF3


15-888
1,3-dichloro-2-propyl
n-Pr
n-Pr
F
H
H
H
Cl
Br
pentafluoroethyl
I
CF3


15-889
1-chloro-3-fluoro-2-propyl
H
H
F
H
H
H
F
I
nonafluoro-2-butyl
F
CF3


15-890
3,3,3-trifluoro-n-propyl
H
H
F
H
H
H
Cl
I
nonafluoro-2-butyl
Cl
CF3


15-891
n-butyl
H
H
F
H
H
H
Cl
I
nonafluoro-2-butyl
Br
CF3


15-892
4,4,4-trifluoro-n-butyl
H
H
F
H
H
H
Cl
I
nonafluoro-2-butyl
I
CF3


15-893
i-butyl
H
H
F
H
H
H
Cl
Me
nonafluoro-2-butyl
H
CF3


15-894
s-butyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
Me
CF3


15-895
vinyl
i-Pr
H
F
H
H
H
Cl
Et
nonafluoro-2-butyl
H
CF3


15-896
benzyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
Et
CF3


15-897
phenyl
H
H
F
H
H
H
Cl
n-Pr
nonafluoro-2-butyl
H
CF3


15-898
methyl
H
i-Pr
F
H
H
H
Cl
H
nonafluoro-2-butyl
n-Pr
CF3


15-899
ethyl
i-Pr
i-Pr
F
H
H
H
Cl
i-Pr
nonafluoro-2-butyl
H
CF3


15-900
2-fluoroethyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
i-Pr
CF3


15-901
2-chloroethyl
H
H
F
H
H
H
Cl
n-Bu
nonafluoro-2-butyl
H
CF3


15-902
2-bromoethyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
n-Bu
CF3


15-903
2-iodoethyl
H
H
F
H
H
H
Cl
i-Bu
nonafluoro-2-butyl
H
CF3


15-904
2-cyanoethyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
i-Bu
CF3


15-905
2,2-difluoroethyl
H
H
F
H
H
H
Cl
s-Bu
nonafluoro-2-butyl
H
C2F5


15-906
2,2-dichloroethyl
H
H
F
H
H
H
Cl
H
nonafluoro-2-butyl
s-Bu
CF3


15-907
2,2,2-trifluoroethyl
H
H
F
H
H
H
Cl
Me
nonafluoro-2-butyl
Me
n-C3F7


15-908
2,2,2-trichloroethyl
H
H
F
H
H
H
Cl
Me
nonafluoro-2-butyl
Et
i-C3F7


15-909
2,2,2-tribromoethyl
C(O)Me
H
F
H
H
H
Cl
Me
nonafluoro-2-butyl
n-Pr
CF3


15-910
n-propyl
H
H
F
H
H
H
Cl
Me
nonafluoro-2-butyl
i-Pr
CF3


15-911
3-fluoro-n-propyl
H
H
F
H
H
H
Cl
Me
nonafluoro-2-butyl
n-Bu
CF3


15-912
3-chloro-n-propyl
H
H
F
H
H
H
Cl
Me
nonafluoro-2-butyl
i-Bu
CF3


15-913
3-bromo-n-propyl
H
C(O)Me
F
H
H
H
Cl
Me
nonafluoro-2-butyl
s-Bu
CF3


15-914
i-propyl
H
H
F
H
H
H
Cl
Et
nonafluoro-2-butyl
Me
n-C3F7


15-915
1,2-difluoro-2-propyl
H
H
F
H
H
H
Cl
Et
nonafluoro-2-butyl
Et
i-C3F7


15-916
1,3-difluoro-2-propyl
C(O)Me
C(O)Me
F
H
H
H
Cl
Et
nonafluoro-2-butyl
n-Pr
CF3


15-917
1,3-dichloro-2-propyl
H
H
F
H
H
H
Cl
Et
nonafluoro-2-butyl
i-Pr
CF3


15-918
methyl
H
H
F
H
H
H
Br
Et
heptafluoroisopropyl
n-Bu
CF3


15-919
ethyl
H
H
F
H
H
H
Br
Et
heptafluoroisopropyl
i-Bu
CF3


15-920
2-fluoroethyl
H
H
F
H
H
H
Br
Et
heptafluoroisopropyl
s-Bu
CF3


15-921
2-chloroethyl
H
H
F
H
H
H
Br
n-Pr
heptafluoroisopropyl
Me
CF3


15-922
2-bromoethyl
H
H
F
H
H
H
Br
n-Pr
heptafluoroisopropyl
Et
CF3


15-923
2-iodoethyl
Me
Et
F
H
H
H
Br
n-Pr
pentafluoroethyl
n-Pr
CF3


15-924
2-cyanoethyl
H
H
F
H
H
H
Br
n-Pr
heptafluoroisopropyl
i-Pr
CF3


15-925
2,2-difluoroethyl
H
H
F
H
H
H
Br
n-Pr
pentafluoroethyl
n-Bu
CF3


15-926
2,2-dichloroethyl
H
H
F
H
H
H
Br
n-Pr
heptafluoroisopropyl
i-Bu
CF3


15-927
2,2,2-trifluoroethyl
H
H
F
H
H
H
Br
n-Pr
heptafluoroisopropyl
s-Bu
CF3


15-928
2,2,2-trichloroethyl
H
H
F
H
H
H
Br
i-Pr
heptafluoroisopropyl
Me
CF3


15-929
2,2,2-tribromoethyl
H
H
F
H
H
H
Br
i-Pr
heptafluoroisopropyl
Et
CF3


15-930
n-propyl
Me
n-Pr
F
H
H
H
Br
i-Pr
heptafluoroisopropyl
n-Pr
CF3


15-931
3-fluoro-n-propyl
H
H
F
H
H
H
Br
i-Pr
heptafluoroisopropyl
i-Pr
CF3


15-932
3-chloro-n-propyl
H
H
F
H
H
H
Br
i-Pr
heptafluoroisopropyl
n-Bu
CF3


15-933
3-bromo-n-propyl
H
H
F
H
H
H
Br
i-Pr
heptafluoroisopropyl
i-Bu
CF3


15-934
i-propyl
Me
i-Pr
F
H
H
H
Br
i-Pr
heptafluoroisopropyl
s-Bu
CF3


15-935
1,2-difluoro-2-propyl
H
H
F
H
H
H
Br
n-Bu
heptafluoroisopropyl
Me
CF3


15-936
1,3-difluoro-2-propyl
H
H
F
H
H
H
Br
n-Bu
heptafluoroisopropyl
Et
CF3


15-937
1,3-dichloro-2-propyl
H
H
F
H
H
H
Br
n-Bu
heptafluoroisopropyl
n-Pr
CF3


15-938
1-chloro-3-fluoro-2-propyl
H
H
F
H
H
H
Br
n-Bu
nonafluoro-2-butyl
i-Pr
CF3


15-939
3,3,3-trifluoro-n-propyl
H
H
F
H
H
H
Br
n-Bu
nonafluoro-2-butyl
n-Bu
CF3


15-940
n-butyl
H
H
F
H
H
H
Br
n-Bu
nonafluoro-2-butyl
i-Bu
CF3


15-941
4,4,4-trifluoro-n-butyl
Me
C(O)Me
F
H
H
H
Br
n-Bu
nonafluoro-2-butyl
s-Bu
CF3


15-942
i-butyl
H
H
F
H
H
H
Br
i-Bu
nonafluoro-2-butyl
Me
CF3


15-943
s-butyl
H
H
F
H
H
H
Br
i-Bu
nonafluoro-2-butyl
Et
CF3


15-944
vinyl
H
H
F
H
H
H
Br
i-Bu
nonafluoro-2-butyl
n-Pr
CF3


15-945
benzyl
H
H
F
H
H
H
Br
i-Bu
nonafluoro-2-butyl
i-Pr
CF3


15-946
phenyl
H
H
F
H
H
H
Br
i-Bu
nonafluoro-2-butyl
n-Bu
CF3


15-947
methyl
H
H
F
H
H
H
Br
i-Bu
nonafluoro-2-butyl
i-Bu
CF3


15-948
ethyl
H
H
F
H
H
H
Br
i-Bu
nonafluoro-2-butyl
s-Bu
C2F5


15-949
2-fluoroethyl
H
H
F
H
H
H
Br
s-Bu
nonafluoro-2-butyl
Me
CF3


15-950
2-chloroethyl
H
H
F
H
H
H
Br
s-Bu
nonafluoro-2-butyl
Et
CF3


15-951
2-bromoethyl
H
H
F
H
H
H
Br
s-Bu
nonafluoro-2-butyl
n-Pr
CF3


15-952
2-iodoethyl
H
H
F
H
H
H
Br
s-Bu
nonafluoro-2-butyl
i-Pr
CF3


15-953
2-cyanoethyl
H
H
F
H
H
H
Br
s-Bu
nonafluoro-2-butyl
n-Bu
CF3


15-954
2,2-difluoroethyl
H
H
F
H
H
H
Br
s-Bu
nonafluoro-2-butyl
i-Bu
CF3


15-955
2,2-dichloroethyl
Et
Me
F
H
H
H
Br
s-Bu
nonafluoro-2-butyl
s-Bu
CF3


15-956
2,2,2-trifluoroethyl
H
H
F
H
H
H
Br
F
nonafluoro-2-butyl
Me
CF3


15-957
2,2,2-trichloroethyl
H
H
F
H
H
H
Br
F
nonafluoro-2-butyl
Et
CF3


15-958
2,2,2-tribromoethyl
H
H
F
H
H
H
Br
F
nonafluoro-2-butyl
n-Pr
CF3


15-959
n-propyl
H
H
F
H
H
H
Br
F
nonafluoro-2-butyl
i-Pr
CF3


15-960
3-fluoro-n-propyl
H
H
F
H
H
H
Br
F
nonafluoro-2-butyl
n-Bu
CF3


15-961
3-chloro-n-propyl
H
H
F
H
H
H
Br
F
nonafluoro-2-butyl
i-Bu
CF3


15-962
3-bromo-n-propyl
Et
n-Pr
F
H
H
H
Br
F
nonafluoro-2-butyl
s-Bu
CF3


15-963
i-propyl
Et
i-Pr
F
H
H
H
Br
Cl
nonafluoro-2-butyl
Me
CF3


15-964
1,2-difluoro-2-propyl
H
H
F
H
H
H
Br
Cl
nonafluoro-2-butyl
Et
CF3


15-965
methyl
H
H
F
H
H
H
I
Cl
pentafluoroethyl
n-Pr
i-C3F7


15-966
ethyl
H
H
F
H
H
H
I
Cl
heptafluoroisopropyl
i-Pr
CF3


15-967
2-fluoroethyl
H
H
F
H
H
H
I
Cl
heptafluoroisopropyl
n-Bu
CF3


15-968
2-chloroethyl
Et
C(O)Me
F
H
H
H
I
Cl
heptafluoroisopropyl
i-Bu
CF3


15-969
2-bromoethyl
H
H
F
H
H
H
I
Cl
heptafluoroisopropyl
s-Bu
CF3


15-970
2-iodoethyl
H
H
F
H
H
H
I
Br
heptafluoroisopropyl
Me
CF3


15-971
2-cyanoethyl
H
H
F
H
H
H
I
Br
heptafluoroisopropyl
Et
CF3


15-972
2,2-difluoroethyl
H
H
F
H
H
H
I
Br
pentafluoroethyl
n-Pr
CF3


15-973
2,2-dichloroethyl
H
H
F
H
H
H
I
Br
heptafluoroisopropyl
i-Pr
CF3


15-974
2,2,2-trifluoroethyl
H
H
F
H
H
H
I
Br
heptafluoroisopropyl
n-Bu
CF3


15-975
2,2,2-trichloroethyl
H
H
F
H
H
H
I
Br
heptafluoroisopropyl
i-Bu
CF3


15-976
2,2,2-tribromoethyl
H
H
F
H
H
H
I
Br
heptafluoroisopropyl
s-Bu
CF3


15-977
n-propyl
n-Pr
Me
F
H
H
H
I
I
heptafluoroisopropyl
Me
CF3


15-978
3-fluoro-n-propyl
H
H
F
H
H
H
I
I
heptafluoroisopropyl
Et
CF3


15-979
3-chloro-n-propyl
n-Pr
Et
F
H
H
H
I
I
heptafluoroisopropyl
n-Pr
CF3


15-980
3-bromo-n-propyl
H
H
F
H
H
H
I
I
heptafluoroisopropyl
i-Pr
CF3


15-981
i-propyl
H
H
F
H
H
H
I
I
heptafluoroisopropyl
n-Bu
CF3


15-982
1,2-difluoro-2-propyl
H
H
F
H
H
H
I
I
heptafluoroisopropyl
i-Bu
CF3


15-983
1,3-difluoro-2-propyl
H
H
F
H
H
H
I
I
heptafluoroisopropyl
s-Bu
CF3


15-984
1,3-dichloro-2-propyl
H
H
F
H
H
H
I
Me
heptafluoroisopropyl
F
C2F5


15-985
1-chloro-3-fluoro-2-propyl
H
H
F
H
H
H
I
Me
nonafluoro-2-butyl
Cl
CF3


15-986
3,3,3-trifluoro-n-propyl
H
H
F
H
H
H
I
Me
nonafluoro-2-butyl
Br
n-C3F7


15-987
n-butyl
H
H
F
H
H
H
I
Me
nonafluoro-2-butyl
I
i-C3F7


15-988
4,4,4-trifluoro-n-butyl
H
H
F
H
H
H
I
Et
nonafluoro-2-butyl
F
CF3


15-989
i-butyl
H
H
F
H
H
H
I
Et
nonafluoro-2-butyl
Cl
CF3


15-990
s-butyl
H
H
F
H
H
H
I
Et
nonafluoro-2-butyl
Br
CF3


15-991
vinyl
n-Pr
i-Pr
F
H
H
H
I
Et
nonafluoro-2-butyl
I
C2F5


15-992
benzyl
H
H
F
H
H
H
I
n-Pr
nonafluoro-2-butyl
F
CF3


15-993
phenyl
H
H
F
H
H
H
I
n-Pr
nonafluoro-2-butyl
Cl
CF3


15-994
methyl
H
H
F
H
H
H
I
n-Pr
nonafluoro-2-butyl
Br
CF3


15-995
ethyl
H
H
F
H
H
H
I
n-Pr
nonafluoro-2-butyl
I
n-C3F7


15-996
2-fluoroethyl
H
H
F
H
H
H
I
i-Pr
nonafluoro-2-butyl
F
i-C3F7


15-997
2-chloroethyl
H
H
F
H
H
H
I
i-Pr
nonafluoro-2-butyl
Cl
CF3


15-998
2-bromoethyl
n-Pr
C(O)Me
F
H
H
H
I
i-Pr
nonafluoro-2-butyl
Br
CF3


15-999
2-iodoethyl
H
H
F
H
H
H
I
i-Pr
nonafluoro-2-butyl
I
CF3


15-1000
2-cyanoethyl
H
H
F
H
H
H
I
n-Bu
nonafluoro-2-butyl
F
CF3


15-1001
2,2-difluoroethyl
H
H
F
H
H
H
I
n-Bu
nonafluoro-2-butyl
Cl
CF3


15-1002
2,2-dichloroethyl
H
H
F
H
H
H
I
n-Bu
nonafluoro-2-butyl
Br
CF3


15-1003
2,2,2-trifluoroethyl
i-Pr
Me
F
H
H
H
I
n-Bu
nonafluoro-2-butyl
I
CF3


15-1004
2,2,2-trichloroethyl
H
H
F
H
H
H
I
i-Bu
nonafluoro-2-butyl
F
CF3


15-1005
2,2,2-tribromoethyl
H
H
F
H
H
H
I
i-Bu
nonafluoro-2-butyl
Cl
CF3


15-1006
n-propyl
H
H
F
H
H
H
I
i-Bu
nonafluoro-2-butyl
Br
CF3


15-1007
3-fluoro-n-propyl
i-Pr
Et
F
H
H
H
I
i-Bu
nonafluoro-2-butyl
I
CF3


15-1008
3-chloro-n-propyl
i-Pr
n-Pr
F
H
H
H
I
s-Bu
nonafluoro-2-butyl
F
CF3


15-1009
3-bromo-n-propyl
H
H
F
H
H
H
I
s-Bu
nonafluoro-2-butyl
Cl
CF3


15-1010
i-propyl
i-Pr
C(O)Me
F
H
H
H
I
s-Bu
nonafluoro-2-butyl
Br
CF3


15-1011
1,2-difluoro-2-propyl
H
H
F
H
H
H
I
s-Bu
nonafluoro-2-butyl
I
CF3


15-1020
2,2-dichloroethyl
H
Et
F
H
H
H
OCF3
F
heptafluoroisopropyl
F
OCF3


15-1050
2,2,2-trifluoroethyl
H
H
F
H
H
H
OCF3
Me
nonafluoro-2-butyl
Me
OCF3


15-1163
2,2-dichloroethyl
H
Et
F
H
H
H
OCF3
F
heptafluoroisopropyl
F
CF3


15-1193
2,2,2-trifluoroethyl
H
H
F
H
H
H
OCF3
Me
nonafluoro-2-butyl
Me
CF3


15-1306
2,2-dichloroethyl
H
Et
F
H
H
H
CF3
F
heptafluoroisopropyl
F
CF3


15-1336
2,2,2-trifluoroethyl
H
H
F
H
H
H
CF3
Me
nonafluoro-2-butyl
Me
CF3


15-1449
2,2-dichloroethyl
H
Et
H
F
H
H
Cl
F
heptafluoroisopropyl
F
Cl


15-1479
2,2,2-trifluoroethyl
H
H
H
F
H
H
Cl
Me
nonafluoro-2-butyl
Me
I


15-1592
2,2-dichloroethyl
H
Et
H
F
H
H
Cl
F
heptafluoroisopropyl
F
OCF3


15-1622
2,2,2-trifluoroethyl
H
H
H
F
H
H
Cl
Me
nonafluoro-2-butyl
Me
OCF3


15-1737
2,2,2-trichloroethyl
H
H
H
F
H
H
Cl
F
heptafluoroisopropyl
Br
CF3


15-1749
n-butyl
H
H
H
F
H
H
Cl
I
nonafluoro-2-butyl
Br
CF3


15-1766
2,2,2-trichloroethyl
H
H
H
F
H
H
Cl
Me
nonafluoro-2-butyl
Et
i-C3F7


15-1772
i-propyl
H
H
H
F
H
H
Cl
Et
nonafluoro-2-butyl
Me
n-C3F7


15-1773
1,2-difluoro-2-propyl
H
H
H
F
H
H
Cl
Et
nonafluoro-2-butyl
Et
i-C3F7


15-1779
2-chloroethyl
H
H
H
F
H
H
Br
n-Pr
heptafluoroisopropyl
Me
CF3


15-1780
2-bromoethyl
H
H
H
F
H
H
Br
n-Pr
heptafluoroisopropyl
Et
CF3


15-1786
2,2,2-trichloroethyl
H
H
H
F
H
H
Br
i-Pr
heptafluoroisopropyl
Me
CF3


15-1787
2,2,2-tribromoethyl
H
H
H
F
H
H
Br
i-Pr
heptafluoroisopropyl
Et
CF3


15-1793
1,2-difluoro-2-propyl
H
H
H
F
H
H
Br
n-Bu
heptafluoroisopropyl
Me
CF3


15-1794
1,3-difluoro-2-propyl
H
H
H
F
H
H
Br
n-Bu
heptafluoroisopropyl
Et
CF3


15-1800
i-butyl
H
H
H
F
H
H
Br
i-Bu
nonafluoro-2-butyl
Me
CF3


15-1801
s-butyl
H
H
H
F
H
H
Br
i-Bu
nonafluoro-2-butyl
Et
CF3


15-1807
2-fluoroethyl
H
H
H
F
H
H
Br
s-Bu
nonafluoro-2-butyl
Me
CF3


15-1808
2-chloroethyl
H
H
H
F
H
H
Br
s-Bu
nonafluoro-2-butyl
Et
CF3


15-1814
2,2,2-trifluoroethyl
H
H
H
F
H
H
Br
F
nonafluoro-2-butyl
Me
CF3


15-1815
2,2,2-trichloroethyl
H
H
H
F
H
H
Br
F
nonafluoro-2-butyl
Et
CF3


15-1821
i-propyl
Et
i-Pr
H
F
H
H
Br
Cl
nonafluoro-2-butyl
Me
CF3


15-1822
1,2-difluoro-2-propyl
H
H
H
F
H
H
Br
Cl
nonafluoro-2-butyl
Et
CF3


15-1828
2-iodoethyl
H
H
H
F
H
H
I
Br
heptafluoroisopropyl
Me
CF3


15-1829
2-cyanoethyl
H
H
H
F
H
H
I
Br
heptafluoroisopropyl
Et
CF3


15-1835
n-propyl
n-Pr
Me
H
F
H
H
I
I
heptafluoroisopropyl
Me
CF3


15-1836
3-fluoro-n-propyl
H
H
H
F
H
H
I
I
heptafluoroisopropyl
Et
CF3


15-1842
1,3-dichloro-2-propyl
H
H
H
F
H
H
I
Me
heptafluoroisopropyl
F
C2F5


15-1843
1-chloro-3-fluoro-2-propyl
H
H
H
F
H
H
I
Me
nonafluoro-2-butyl
Cl
CF3


15-1846
4,4,4-trifluoro-n-butyl
H
H
H
F
H
H
I
Et
nonafluoro-2-butyl
F
CF3


15-1847
i-butyl
H
H
H
F
H
H
I
Et
nonafluoro-2-butyl
Cl
CF3


15-1850
benzyl
H
H
H
F
H
H
I
n-Pr
nonafluoro-2-butyl
F
CF3


15-1851
phenyl
H
H
H
F
H
H
I
n-Pr
nonafluoro-2-butyl
Cl
CF3


15-1854
2-fluoroethyl
H
H
H
F
H
H
I
i-Pr
nonafluoro-2-butyl
F
i-C3F7


15-1855
2-chloroethyl
H
H
H
F
H
H
I
i-Pr
nonafluoro-2-butyl
Cl
CF3


15-1858
2-cyanoethyl
H
H
H
F
H
H
I
n-Bu
nonafluoro-2-butyl
F
CF3


15-1859
2,2-difluoroethyl
H
H
H
F
H
H
I
n-Bu
nonafluoro-2-butyl
Cl
CF3


15-1862
2,2,2-trichloroethyl
H
H
H
F
H
H
I
i-Bu
nonafluoro-2-butyl
F
CF3


15-1863
2,2,2-tribromoethyl
H
H
H
F
H
H
I
i-Bu
nonafluoro-2-butyl
Cl
CF3


15-1866
3-chloro-n-propyl
i-Pr
n-Pr
H
F
H
H
I
s-Bu
nonafluoro-2-butyl
F
CF3


15-1867
3-bromo-n-propyl
H
H
H
F
H
H
I
s-Bu
nonafluoro-2-butyl
Cl
CF3


15-1878
2,2-dichloroethyl
H
Et
H
F
H
H
OCF3
F
heptafluoroisopropyl
F
OCF3


15-1908
2,2,2-trifluoroethyl
H
H
H
F
H
H
OCF3
Me
nonafluoro-2-butyl
Me
OCF3


15-2021
2,2-dichloroethyl
H
Et
H
F
H
H
OCF3
F
heptafluoroisopropyl
F
CF3


15-2051
2,2,2-trifluoroethyl
H
H
H
F
H
H
OCF3
Me
nonafluoro-2-butyl
Me
CF3


15-2164
2,2-dichloroethyl
H
Et
H
F
H
H
CF3
F
heptafluoroisopropyl
F
CF3


15-2194
2,2,2-trifluoroethyl
H
H
H
F
H
H
CF3
Me
nonafluoro-2-butyl
Me
CF3


15-2307
2,2-dichloroethyl
H
Et
F
F
H
H
Cl
F
heptafluoroisopropyl
F
Cl


15-2337
2,2,2-trifluoroethyl
H
H
F
F
H
H
Cl
Me
nonafluoro-2-butyl
Me
I


15-2450
2,2-dichloroethyl
H
Et
F
F
H
H
Cl
F
heptafluoroisopropyl
F
OCF3


15-2480
2,2,2-trifluoroethyl
H
H
F
F
H
H
Cl
Me
nonafluoro-2-butyl
Me
OCF3


15-2585
methyl
H
H
F
F
H
H
Cl
F
heptafluoroisopropyl
H
CF3


15-2591
2-cyanoethyl
Et
H
F
F
H
H
Cl
I
heptafluoroisopropyl
H
C2F5


15-2594
2,2,2-trifluoroethyl
H
H
F
F
H
H
Cl
F
heptafluoroisopropyl
Cl
CF3


15-2602
1,2-difluoro-2-propyl
H
H
F
F
H
H
Cl
Br
heptafluoroisopropyl
Cl
CF3


15-2609
i-butyl
H
H
F
F
H
H
Cl
Me
nonafluoro-2-butyl
H
CF3


15-2610
s-butyl
H
H
F
F
H
H
Cl
H
nonafluoro-2-butyl
Me
CF3


15-2611
vinyl
i-Pr
H
F
F
H
H
Cl
Et
nonafluoro-2-butyl
H
CF3


15-2612
benzyl
H
H
F
F
H
H
Cl
H
nonafluoro-2-butyl
Et
CF3


15-2623
2,2,2-trifluoroethyl
H
H
F
F
H
H
Cl
Me
nonafluoro-2-butyl
Me
n-C3F7


15-2624
2,2,2-trichloroethyl
H
H
F
F
H
H
Cl
Me
nonafluoro-2-butyl
Et
i-C3F7


15-2630
i-propyl
H
H
F
F
H
H
Cl
Et
nonafluoro-2-butyl
Me
n-C3F7


15-2631
1,2-difluoro-2-propyl
H
H
F
F
H
H
Cl
Et
nonafluoro-2-butyl
Et
i-C3F7


15-2637
2-chloroethyl
H
H
F
F
H
H
Br
n-Pr
heptafluoroisopropyl
Me
CF3


15-2638
2-bromoethyl
H
H
F
F
H
H
Br
n-Pr
heptafluoroisopropyl
Et
CF3


15-2644
2,2,2-trichloroethyl
H
H
F
F
H
H
Br
i-Pr
heptafluoroisopropyl
Me
CF3


15-2645
2,2,2-tribromoethyl
H
H
F
F
H
H
Br
i-Pr
heptafluoroisopropyl
Et
CF3


15-2651
1,2-difluoro-2-propyl
H
H
F
F
H
H
Br
n-Bu
heptafluoroisopropyl
Me
CF3


15-2652
1,3-difluoro-2-propyl
H
H
F
F
H
H
Br
n-Bu
heptafluoroisopropyl
Et
CF3


15-2658
i-butyl
H
H
F
F
H
H
Br
i-Bu
nonafluoro-2-butyl
Me
CF3


15-2659
s-butyl
H
H
F
F
H
H
Br
i-Bu
nonafluoro-2-butyl
Et
CF3


15-2665
2-fluoroethyl
H
H
F
F
H
H
Br
s-Bu
nonafluoro-2-butyl
Me
CF3


15-2666
2-chloroethyl
H
H
F
F
H
H
Br
s-Bu
nonafluoro-2-butyl
Et
CF3


15-2672
2,2,2-trifluoroethyl
H
H
F
F
H
H
Br
F
nonafluoro-2-butyl
Me
CF3


15-2673
2,2,2-trichloroethyl
H
H
F
F
H
H
Br
F
nonafluoro-2-butyl
Et
CF3


15-2679
i-propyl
Et
i-Pr
F
F
H
H
Br
Cl
nonafluoro-2-butyl
Me
CF3


15-2680
1,2-difluoro-2-propyl
H
H
F
F
H
H
Br
Cl
nonafluoro-2-butyl
Et
CF3


15-2686
2-iodoethyl
H
H
F
F
H
H
I
Br
heptafluoroisopropyl
Me
CF3


15-2687
2-cyanoethyl
H
H
F
F
H
H
I
Br
heptafluoroisopropyl
Et
CF3


15-2693
n-propyl
n-Pr
Me
F
F
H
H
I
I
heptafluoroisopropyl
Me
CF3


15-2694
3-fluoro-n-propyl
H
H
F
F
H
H
I
I
heptafluoroisopropyl
Et
CF3


15-2700
1,3-dichloro-2-propyl
H
H
F
F
H
H
I
Me
heptafluoroisopropyl
F
C2F5


15-2701
1-chloro-3-fluoro-2-propyl
H
H
F
F
H
H
I
Me
nonafluoro-2-butyl
Cl
CF3


15-2704
4,4,4-trifluoro-n-butyl
H
H
F
F
H
H
I
Et
nonafluoro-2-butyl
F
CF3


15-2705
i-butyl
H
H
F
F
H
H
I
Et
nonafluoro-2-butyl
Cl
CF3


15-2708
benzyl
H
H
F
F
H
H
I
n-Pr
nonafluoro-2-butyl
F
CF3


15-2709
phenyl
H
H
F
F
H
H
I
n-Pr
nonafluoro-2-butyl
Cl
CF3


15-2712
2-fluoroethyl
H
H
F
F
H
H
I
i-Pr
nonafluoro-2-butyl
F
i-C3F7


15-2713
2-chloroethyl
H
H
F
F
H
H
I
i-Pr
nonafluoro-2-butyl
Cl
CF3


15-2716
2-cyanoethyl
H
H
F
F
H
H
I
n-Bu
nonafluoro-2-butyl
F
CF3


15-2717
2,2-difluoroethyl
H
H
F
F
H
H
I
n-Bu
nonafluoro-2-butyl
Cl
CF3


15-2720
2,2,2-trichloroethyl
H
H
F
F
H
H
I
i-Bu
nonafluoro-2-butyl
F
CF3


15-2721
2,2,2-tribromoethyl
H
H
F
F
H
H
I
i-Bu
nonafluoro-2-butyl
Cl
CF3


15-2724
3-chloro-n-propyl
i-Pr
n-Pr
F
F
H
H
I
s-Bu
nonafluoro-2-butyl
F
CF3


15-2725
3-bromo-n-propyl
H
H
F
F
H
H
I
s-Bu
nonafluoro-2-butyl
Cl
CF3


15-2736
2,2-dichloroethyl
H
Et
F
F
H
H
OCF3
F
heptafluoroisopropyl
F
OCF3


15-2766
2,2,2-trifluoroethyl
H
H
F
F
H
H
OCF3
Me
nonafluoro-2-butyl
Me
OCF3


15-2879
2,2-dichloroethyl
H
Et
F
F
H
H
OCF3
F
heptafluoroisopropyl
F
CF3


15-2909
2,2,2-trifluoroethyl
H
H
F
F
H
H
OCF3
Me
nonafluoro-2-butyl
Me
CF3


15-3022
2,2-dichloroethyl
H
Et
F
F
H
H
CF3
F
heptafluoroisopropyl
F
CF3


15-3052
2,2,2-trifluoroethyl
H
H
F
F
H
H
CF3
Me
nonafluoro-2-butyl
Me
CF3


15-3157
2,2,2-trichloroethyl
H
H
F
F
F
H
Cl
F
pentafluoroethyl
H
Cl


15-3158
2,2,2-trichloroethyl
Me
H
F
F
F
H
Cl
H
heptafluoroisopropyl
F
Cl


15-3159
2,2,2-trichloroethyl
H
Me
F
F
F
H
Br
Cl
heptafluoroisopropyl
H
Br


15-3160
2,2,2-trichloroethyl
Me
Me
F
F
F
H
I
H
heptafluoroisopropyl
Cl
I


15-3161
2,2,2-trichloroethyl
H
H
F
F
F
H
Cl
Br
heptafluoroisopropyl
H
OCF3


15-3162
2,2,2-trichloroethyl
H
H
F
F
F
H
Br
H
heptafluoroisopropyl
Br
OCF3


15-3163
2,2,2-trichloroethyl
Et
H
F
F
F
H
I
I
heptafluoroisopropyl
H
OCF3


15-3164
2,2,2-trichloroethyl
H
H
F
F
F
H
Cl
H
heptafluoroisopropyl
I
CF3


15-3165
2,2,2-trichloroethyl
H
Et
F
F
F
H
Br
F
heptafluoroisopropyl
F
CF3


15-3166
2,2,2-trichloroethyl
H
H
F
F
F
H
I
F
heptafluoroisopropyl
Cl
CF3


15-3167
2,2,2-trichloroethyl
H
H
F
F
F
H
CF3
F
heptafluoroisopropyl
Br
CF3


15-3168
2,2,2-trichloroethyl
Et
Et
F
F
F
H
Cl
F
nonafluoro-2-butyl
I
Cl


15-3169
2,2,2-trichloroethyl
H
H
F
F
F
H
Br
Cl
nonafluoro-2-butyl
F
Br


15-3170
2,2,2-trichloroethyl
H
H
F
F
F
H
I
Cl
nonafluoro-2-butyl
Cl
I


15-3171
2,2,2-trichloroethyl
n-Pr
H
F
F
F
H
Cl
Cl
nonafluoro-2-butyl
Br
OCF3


15-3172
2,2,2-trichloroethyl
H
H
F
F
F
H
Br
Cl
nonafluoro-2-butyl
I
OCF3


15-3173
2,2,2-trichloroethyl
H
n-Pr
F
F
F
H
I
Br
nonafluoro-2-butyl
F
OCF3


15-3174
2,2,2-trichloroethyl
H
H
F
F
F
H
Cl
Br
nonafluoro-2-butyl
Cl
CF3


15-3175
2,2,2-trichloroethyl
H
H
F
F
F
H
Br
Br
nonafluoro-2-butyl
Br
CF3


15-3176
2,2,2-trichloroethyl
n-Pr
n-Pr
F
F
F
H
I
Br
nonafluoro-2-butyl
I
CF3


15-3177
2,2,2-trichloroethyl
H
H
F
F
F
H
CF3
I
nonafluoro-2-butyl
F
CF3


15-3178
2,2,2-trichloroethyl
H
H
H
H
F
H
Cl
I
pentafluoroethyl
Cl
Cl


15-3179
2,2,2-trichloroethyl
H
H
H
H
F
H
Cl
I
heptafluoroisopropyl
Br
Cl


15-3180
2,2,2-trichloroethyl
H
H
H
H
F
H
Br
I
heptafluoroisopropyl
I
Br


15-3181
2,2,2-trichloroethyl
H
H
H
H
F
H
I
Me
heptafluoroisopropyl
H
I


15-3182
2,2,2-trichloroethyl
H
H
H
H
F
H
Cl
H
heptafluoroisopropyl
Me
OCF3


15-3183
2,2,2-trichloroethyl
i-Pr
H
H
H
F
H
Br
Et
heptafluoroisopropyl
H
OCF3


15-3184
2,2,2-trichloroethyl
H
H
H
H
F
H
I
H
heptafluoroisopropyl
Et
OCF3


15-3185
2,2,2-trichloroethyl
H
H
H
H
F
H
Cl
n-Pr
heptafluoroisopropyl
H
CF3


15-3186
2,2,2-trichloroethyl
H
i-Pr
H
H
F
H
Br
H
heptafluoroisopropyl
n-Pr
CF3


15-3187
2,2,2-trichloroethyl
i-Pr
i-Pr
H
H
F
H
I
i-Pr
heptafluoroisopropyl
H
CF3


15-3188
2,2,2-trichloroethyl
H
H
H
H
F
H
CF3
H
heptafluoroisopropyl
i-Pr
CF3


15-3189
2,2,2-trichloroethyl
H
H
H
H
F
H
Cl
n-Bu
nonafluoro-2-butyl
H
Cl


15-3190
2,2,2-trichloroethyl
H
H
H
H
F
H
Br
H
nonafluoro-2-butyl
n-Bu
Br


15-3191
2,2,2-trichloroethyl
H
H
H
H
F
H
I
i-Bu
nonafluoro-2-butyl
H
I


15-3192
2,2,2-trichloroethyl
H
H
H
H
F
H
Cl
H
nonafluoro-2-butyl
i-Bu
OCF3


15-3193
2,2,2-trichloroethyl
H
H
H
H
F
H
Br
s-Bu
nonafluoro-2-butyl
H
OCF3


15-3194
2,2,2-trichloroethyl
H
H
H
H
F
H
I
H
nonafluoro-2-butyl
s-Bu
OCF3


15-3195
2,2,2-trichloroethyl
H
H
H
H
F
H
Cl
Me
nonafluoro-2-butyl
Me
CF3


15-3196
2,2,2-trichloroethyl
H
H
H
H
F
H
Br
Me
nonafluoro-2-butyl
Et
CF3


15-3197
2,2,2-trichloroethyl
C(O)Me
H
H
H
F
H
I
Me
nonafluoro-2-butyl
n-Pr
CF3


15-3198
2,2,2-trichloroethyl
H
H
H
H
F
H
CF3
Me
nonafluoro-2-butyl
i-Pr
CF3


15-3199
2,2,2-trichloroethyl
H
H
H
H
H
F
Cl
Me
pentafluoroethyl
n-Bu
Cl


15-3200
2,2,2-trichloroethyl
H
H
H
H
H
F
Br
Me
heptafluoroisopropyl
i-Bu
Br


15-3201
2,2,2-trichloroethyl
H
C(O)Me
H
H
H
F
Br
Me
heptafluoroisopropyl
s-Bu
OCF3


15-3202
2,2,2-trichloroethyl
H
H
H
H
H
F
I
Et
heptafluoroisopropyl
Me
CF3


15-3203
2,2,2-trichloroethyl
H
H
H
H
H
F
CF3
Et
heptafluoroisopropyl
Et
CF3


15-3204
2,2,2-trichloroethyl
C(O)Me
C(O)Me
H
H
H
F
I
Et
nonafluoro-2-butyl
n-Pr
I


15-3205
2,2,2-trichloroethyl
H
H
H
H
H
F
Cl
Et
nonafluoro-2-butyl
i-Pr
OCF3


15-3206
2,2,2-trichloroethyl
H
H
H
H
H
F
Br
Et
nonafluoro-2-butyl
n-Bu
CF3


15-3207
2,2,2-trichloroethyl
H
H
H
H
H
F
CF3
Et
nonafluoro-2-butyl
i-Bu
CF3


15-3208
2,2,2-trichloroethyl
H
H
F
H
F
H
Cl
Et
pentafluoroethyl
s-Bu
Cl


15-3209
2,2,2-trichloroethyl
H
H
F
H
F
H
Cl
n-Pr
heptafluoroisopropyl
Me
Cl


15-3210
2,2,2-trichloroethyl
H
H
F
H
F
H
Br
n-Pr
heptafluoroisopropyl
Et
Br


15-3211
2,2,2-trichloroethyl
Me
Et
F
H
F
H
I
n-Pr
heptafluoroisopropyl
n-Pr
I


15-3212
2,2,2-trichloroethyl
H
H
F
H
F
H
Cl
n-Pr
heptafluoroisopropyl
i-Pr
OCF3


15-3213
2,2,2-trichloroethyl
H
H
F
H
F
H
Br
n-Pr
heptafluoroisopropyl
n-Bu
OCF3


15-3214
2,2,2-trichloroethyl
H
H
F
H
F
H
I
n-Pr
heptafluoroisopropyl
i-Bu
OCF3


15-3215
2,2,2-trichloroethyl
H
H
F
H
F
H
Cl
n-Pr
heptafluoroisopropyl
s-Bu
CF3


15-3216
2,2,2-trichloroethyl
Me
n-Pr
F
H
F
H
Br
i-Pr
heptafluoroisopropyl
Me
CF3


15-3217
2,2,2-trichloroethyl
H
H
F
H
F
H
I
i-Pr
heptafluoroisopropyl
Et
CF3


15-3218
2,2,2-trichloroethyl
H
H
F
H
F
H
CF3
i-Pr
heptafluoroisopropyl
n-Pr
CF3


15-3219
2,2,2-trichloroethyl
H
H
F
H
F
H
Cl
i-Pr
nonafluoro-2-butyl
i-Pr
Cl


15-3220
2,2,2-trichloroethyl
H
H
F
H
F
H
Br
i-Pr
nonafluoro-2-butyl
n-Bu
Br


15-3221
2,2,2-trichloroethyl
H
H
F
H
F
H
I
i-Pr
nonafluoro-2-butyl
i-Bu
I


15-3222
2,2,2-trichloroethyl
Me
i-Pr
F
H
F
H
Cl
i-Pr
nonafluoro-2-butyl
s-Bu
OCF3


15-3223
2,2,2-trichloroethyl
H
H
F
H
F
H
Br
n-Bu
nonafluoro-2-butyl
Me
OCF3


15-3224
2,2,2-trichloroethyl
H
H
F
H
F
H
I
n-Bu
nonafluoro-2-butyl
Et
OCF3


15-3225
2,2,2-trichloroethyl
H
H
F
H
F
H
Br
n-Bu
nonafluoro-2-butyl
n-Pr
CF3


15-3226
2,2,2-trichloroethyl
H
H
F
H
F
H
I
n-Bu
nonafluoro-2-butyl
i-Pr
CF3


15-3227
2,2,2-trichloroethyl
H
H
F
H
F
H
CF3
n-Bu
nonafluoro-2-butyl
n-Bu
CF3


15-3228
2,2,2-trichloroethyl
H
H
F
H
H
F
Cl
n-Bu
pentafluoroethyl
i-Bu
Cl


15-3229
2,2,2-trichloroethyl
Me
C(O)Me
F
H
H
F
Br
n-Bu
heptafluoroisopropyl
s-Bu
Br


15-3230
2,2,2-trichloroethyl
H
H
F
H
H
F
Br
i-Bu
heptafluoroisopropyl
Me
OCF3


15-3231
2,2,2-trichloroethyl
H
H
F
H
H
F
I
i-Bu
heptafluoroisopropyl
Et
CF3


15-3232
2,2,2-trichloroethyl
H
H
F
H
H
F
CF3
i-Bu
heptafluoroisopropyl
n-Pr
CF3


15-3233
2,2,2-trichloroethyl
H
H
F
H
H
F
I
i-Bu
nonafluoro-2-butyl
i-Pr
I


15-3234
2,2,2-trichloroethyl
H
H
F
H
H
F
Cl
i-Bu
nonafluoro-2-butyl
n-Bu
OCF3


15-3235
2,2,2-trichloroethyl
H
H
F
H
H
F
Br
i-Bu
nonafluoro-2-butyl
i-Bu
CF3


15-3236
2,2,2-trichloroethyl
H
H
F
H
H
F
CF3
i-Bu
nonafluoro-2-butyl
s-Bu
CF3


15-3237
2,2,2-trichloroethyl
H
H
H
F
F
H
Cl
s-Bu
pentafluoroethyl
Me
Cl


15-3238
2,2,2-trichloroethyl
H
H
H
F
F
H
Br
s-Bu
heptafluoroisopropyl
Et
Br


15-3239
2,2,2-trichloroethyl
H
H
H
F
F
H
Br
s-Bu
heptafluoroisopropyl
n-Pr
OCF3


15-3240
2,2,2-trichloroethyl
H
H
H
F
F
H
I
s-Bu
heptafluoroisopropyl
i-Pr
CF3


15-3241
2,2,2-trichloroethyl
H
H
H
F
F
H
CF3
s-Bu
heptafluoroisopropyl
n-Bu
CF3


15-3242
2,2,2-trichloroethyl
H
H
H
F
F
H
I
s-Bu
nonafluoro-2-butyl
i-Bu
I


15-3243
2,2,2-trichloroethyl
Et
Me
H
F
F
H
Cl
s-Bu
nonafluoro-2-butyl
s-Bu
OCF3


15-3244
2,2,2-trichloroethyl
H
H
H
F
F
H
Br
F
nonafluoro-2-butyl
Me
CF3


15-3245
2,2,2-trichloroethyl
H
H
H
F
F
H
CF3
F
nonafluoro-2-butyl
Et
CF3


15-3246
2,2,2-trichloroethyl
H
H
H
F
H
F
Cl
F
pentafluoroethyl
n-Pr
Cl


15-3247
2,2,2-trichloroethyl
H
H
H
F
H
F
Br
F
heptafluoroisopropyl
i-Pr
Br


15-3248
2,2,2-trichloroethyl
H
H
H
F
H
F
Br
F
heptafluoroisopropyl
n-Bu
OCF3


15-3249
2,2,2-trichloroethyl
H
H
H
F
H
F
I
F
heptafluoroisopropyl
i-Bu
CF3


15-3250
2,2,2-trichloroethyl
Et
n-Pr
H
F
H
F
CF3
F
heptafluoroisopropyl
s-Bu
CF3


15-3251
2,2,2-trichloroethyl
Et
i-Pr
H
F
H
F
I
Cl
nonafluoro-2-butyl
Me
I


15-3252
2,2,2-trichloroethyl
H
H
H
F
H
F
Cl
Cl
nonafluoro-2-butyl
Et
OCF3


15-3253
2,2,2-trichloroethyl
H
H
H
F
H
F
Br
Cl
nonafluoro-2-butyl
n-Pr
CF3


15-3254
2,2,2-trichloroethyl
H
H
H
F
H
F
CF3
Cl
nonafluoro-2-butyl
i-Pr
CF3


15-3255
2,2,2-trichloroethyl
H
H
H
H
F
F
Cl
Cl
pentafluoroethyl
n-Bu
Cl


15-3256
2,2,2-trichloroethyl
Et
C(O)Me
H
H
F
F
Br
Cl
heptafluoroisopropyl
i-Bu
Br


15-3257
2,2,2-trichloroethyl
H
H
H
H
F
F
Br
Cl
heptafluoroisopropyl
s-Bu
OCF3


15-3258
2,2,2-trichloroethyl
H
H
H
H
F
F
I
Br
heptafluoroisopropyl
Me
CF3


15-3259
2,2,2-trichloroethyl
H
H
H
H
F
F
CF3
Br
heptafluoroisopropyl
Et
CF3


15-3260
2,2,2-trichloroethyl
H
H
H
H
F
F
I
Br
nonafluoro-2-butyl
n-Pr
I


15-3261
2,2,2-trichloroethyl
H
H
H
H
F
F
Cl
Br
nonafluoro-2-butyl
i-Pr
OCF3


15-3262
2,2,2-trichloroethyl
H
H
H
H
F
F
Br
Br
nonafluoro-2-butyl
n-Bu
CF3


15-3263
2,2,2-trichloroethyl
H
H
H
H
F
F
CF3
Br
nonafluoro-2-butyl
i-Bu
CF3


15-3264
2,2,2-trichloroethyl
H
H
F
F
H
F
Cl
Br
pentafluoroethyl
s-Bu
Cl


15-3265
2,2,2-trichloroethyl
n-Pr
Me
F
F
H
F
Br
I
heptafluoroisopropyl
Me
Br


15-3266
2,2,2-trichloroethyl
H
H
F
F
H
F
Br
I
heptafluoroisopropyl
Et
OCF3


15-3267
2,2,2-trichloroethyl
n-Pr
Et
F
F
H
F
I
I
heptafluoroisopropyl
n-Pr
CF3


15-3268
2,2,2-trichloroethyl
H
H
F
F
H
F
CF3
I
heptafluoroisopropyl
i-Pr
CF3


15-3269
2,2,2-trichloroethyl
H
H
F
F
H
F
I
I
nonafluoro-2-butyl
n-Bu
I


15-3270
2,2,2-trichloroethyl
H
H
F
F
H
F
Cl
I
nonafluoro-2-butyl
i-Bu
OCF3


15-3271
2,2,2-trichloroethyl
H
H
F
F
H
F
Br
I
nonafluoro-2-butyl
s-Bu
CF3


15-3272
2,2,2-trichloroethyl
H
H
F
F
H
F
CF3
Me
nonafluoro-2-butyl
F
CF3


15-3273
2,2,2-trichloroethyl
H
H
F
H
F
F
Cl
Me
pentafluoroethyl
Cl
Cl


15-3274
2,2,2-trichloroethyl
H
H
F
H
F
F
Br
Me
heptafluoroisopropyl
Br
Br


15-3275
2,2,2-trichloroethyl
H
H
F
H
F
F
Br
Me
heptafluoroisopropyl
I
OCF3


15-3276
2,2,2-trichloroethyl
H
H
F
H
F
F
I
Et
heptafluoroisopropyl
F
CF3


15-3277
2,2,2-trichloroethyl
H
H
F
H
F
F
CF3
Et
heptafluoroisopropyl
Cl
CF3


15-3278
2,2,2-trichloroethyl
H
H
F
H
F
F
I
Et
nonafluoro-2-butyl
Br
I


15-3279
2,2,2-trichloroethyl
n-Pr
i-Pr
F
H
F
F
Cl
Et
nonafluoro-2-butyl
I
OCF3


15-3280
2,2,2-trichloroethyl
H
H
F
H
F
F
Br
n-Pr
nonafluoro-2-butyl
F
CF3


15-3281
2,2,2-trichloroethyl
H
H
F
H
F
F
CF3
n-Pr
nonafluoro-2-butyl
Cl
CF3


15-3282
2,2,2-trichloroethyl
H
H
H
F
F
F
Cl
n-Pr
pentafluoroethyl
Br
Cl


15-3283
2,2,2-trichloroethyl
H
H
H
F
F
F
Br
n-Pr
heptafluoroisopropyl
I
Br


15-3284
2,2,2-trichloroethyl
H
H
H
F
F
F
Br
i-Pr
heptafluoroisopropyl
F
OCF3


15-3285
2,2,2-trichloroethyl
H
H
H
F
F
F
I
i-Pr
heptafluoroisopropyl
Cl
CF3


15-3286
2,2,2-trichloroethyl
n-Pr
C(O)Me
H
F
F
F
CF3
i-Pr
heptafluoroisopropyl
Br
CF3


15-3287
2,2,2-trichloroethyl
H
H
H
F
F
F
I
i-Pr
nonafluoro-2-butyl
I
I


15-3288
2,2,2-trichloroethyl
H
H
H
F
F
F
Cl
n-Bu
nonafluoro-2-butyl
F
OCF3


15-3289
2,2,2-trichloroethyl
H
H
H
F
F
F
Br
n-Bu
nonafluoro-2-butyl
Cl
CF3


15-3290
2,2,2-trichloroethyl
H
H
H
F
F
F
CF3
n-Bu
nonafluoro-2-butyl
Br
CF3


15-3291
2,2,2-trichloroethyl
i-Pr
Me
F
F
F
F
Cl
n-Bu
pentafluoroethyl
I
Cl


15-3292
2,2,2-trichloroethyl
H
H
F
F
F
F
Br
i-Bu
heptafluoroisopropyl
F
Br


15-3293
2,2,2-trichloroethyl
H
H
F
F
F
F
Br
i-Bu
heptafluoroisopropyl
Cl
OCF3


15-3294
2,2,2-trichloroethyl
H
H
F
F
F
F
I
i-Bu
heptafluoroisopropyl
Br
CF3


15-3295
2,2,2-trichloroethyl
i-Pr
Et
F
F
F
F
CF3
i-Bu
heptafluoroisopropyl
I
CF3


15-3296
2,2,2-trichloroethyl
i-Pr
n-Pr
F
F
F
F
I
s-Bu
nonafluoro-2-butyl
F
I


15-3297
2,2,2-trichloroethyl
H
H
F
F
F
F
Cl
s-Bu
nonafluoro-2-butyl
Cl
OCF3


15-3298
2,2,2-trichloroethyl
i-Pr
C(O)Me
F
F
F
F
Br
s-Bu
nonafluoro-2-butyl
Br
CF3


15-3299
2,2,2-trichloroethyl
H
H
F
F
F
F
CF3
s-Bu
nonafluoro-2-butyl
I
CF3


15-3308
2,2-dichloroethyl
H
Et
H
CN
H
H
Cl
F
heptafluoroisopropyl
F
OCF3


15-3338
2,2,2-trifluoroethyl
H
H
H
CN
H
H
Cl
Me
nonafluoro-2-butyl
Me
OCF3


15-3447
2-bromoethyl
H
H
H
CN
H
H
F
Br
heptafluoroisopropyl
H
CF3


15-3457
3-chloro-n-propyl
n-Pr
H
H
CN
H
H
Cl
Cl
heptafluoroisopropyl
Br
CF3


15-3464
3,3,3-trifluoro-n-propyl
H
H
H
CN
H
H
Cl
I
nonafluoro-2-butyl
Cl
CF3


15-3467
i-butyl
H
H
H
CN
H
H
Cl
Me
nonafluoro-2-butyl
H
CF3


15-3468
s-butyl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
Me
CF3


15-3469
vinyl
i-Pr
H
H
CN
H
H
Cl
Et
nonafluoro-2-butyl
H
CF3


15-3470
benzyl
H
H
H
CN
H
H
Cl
H
nonafluoro-2-butyl
Et
CF3


15-3481
2,2,2-trifluoroethyl
H
H
H
CN
H
H
Cl
Me
nonafluoro-2-butyl
Me
n-C3F7


15-3482
2,2,2-trichloroethyl
H
H
H
CN
H
H
Cl
Me
nonafluoro-2-butyl
Et
i-C3F7


15-3488
i-propyl
H
H
H
CN
H
H
Cl
Et
nonafluoro-2-butyl
Me
n-C3F7


15-3489
1,2-difluoro-2-propyl
H
H
H
CN
H
H
Cl
Et
nonafluoro-2-butyl
Et
i-C3F7


15-3495
2-chloroethyl
H
H
H
CN
H
H
Br
n-Pr
heptafluoroisopropyl
Me
CF3


15-3496
2-bromoethyl
H
H
H
CN
H
H
Br
n-Pr
heptafluoroisopropyl
Et
CF3


15-3502
2,2,2-trichloroethyl
H
H
H
CN
H
H
Br
i-Pr
heptafluoroisopropyl
Me
CF3


15-3503
2,2,2-tribromoethyl
H
H
H
CN
H
H
Br
i-Pr
heptafluoroisopropyl
Et
CF3


15-3509
1,2-difluoro-2-propyl
H
H
H
CN
H
H
Br
n-Bu
heptafluoroisopropyl
Me
CF3


15-3510
1,3-difluoro-2-propyl
H
H
H
CN
H
H
Br
n-Bu
heptafluoroisopropyl
Et
CF3


15-3516
i-butyl
H
H
H
CN
H
H
Br
i-Bu
nonafluoro-2-butyl
Me
CF3


15-3517
s-butyl
H
H
H
CN
H
H
Br
i-Bu
nonafluoro-2-butyl
Et
CF3


15-3523
2-fluoroethyl
H
H
H
CN
H
H
Br
s-Bu
nonafluoro-2-butyl
Me
CF3


15-3524
2-chloroethyl
H
H
H
CN
H
H
Br
s-Bu
nonafluoro-2-butyl
Et
CF3


15-3530
2,2,2-trifluoroethyl
H
H
H
CN
H
H
Br
F
nonafluoro-2-butyl
Me
CF3


15-3531
2,2,2-trichloroethyl
H
H
H
CN
H
H
Br
F
nonafluoro-2-butyl
Et
CF3


15-3537
i-propyl
Et
i-Pr
H
CN
H
H
Br
Cl
nonafluoro-2-butyl
Me
CF3


15-3538
1,2-difluoro-2-propyl
H
H
H
CN
H
H
Br
Cl
nonafluoro-2-butyl
Et
CF3


15-3544
2-iodoethyl
H
H
H
CN
H
H
I
Br
heptafluoroisopropyl
Me
CF3


15-3545
2-cyanoethyl
H
H
H
CN
H
H
I
Br
heptafluoroisopropyl
Et
CF3


15-3551
n-propyl
n-Pr
Me
H
CN
H
H
I
I
heptafluoroisopropyl
Me
CF3


15-3552
3-fluoro-n-propyl
H
H
H
CN
H
H
I
I
heptafluoroisopropyl
Et
CF3


15-3558
1,3-dichloro-2-propyl
H
H
H
CN
H
H
I
Me
heptafluoroisopropyl
F
C2F5


15-3559
1-chloro-3-fluoro-2-propyl
H
H
H
CN
H
H
I
Me
nonafluoro-2-butyl
Cl
CF3


15-3562
4,4,4-trifluoro-n-butyl
H
H
H
CN
H
H
I
Et
nonafluoro-2-butyl
F
CF3


15-3563
i-butyl
H
H
H
CN
H
H
I
Et
nonafluoro-2-butyl
Cl
CF3


15-3566
benzyl
H
H
H
CN
H
H
I
n-Pr
nonafluoro-2-butyl
F
CF3


15-3567
phenyl
H
H
H
CN
H
H
I
n-Pr
nonafluoro-2-butyl
Cl
CF3


15-3570
2-fluoroethyl
H
H
H
CN
H
H
I
i-Pr
nonafluoro-2-butyl
F
i-C3F7


15-3571
2-chloroethyl
H
H
H
CN
H
H
I
i-Pr
nonafluoro-2-butyl
Cl
CF3


15-3574
2-cyanoethyl
H
H
H
CN
H
H
I
n-Bu
nonafluorc-2-butyl
F
CF3


15-3575
2,2-difluoroethyl
H
H
H
CN
H
H
I
n-Bu
nonafluoro-2-butyl
Cl
CF3


15-3578
2,2,2-trichloroethyl
H
H
H
CN
H
H
I
i-Bu
nonafluoro-2-butyl
F
CF3


15-3579
2,2,2-tribromoethyl
H
H
H
CN
H
H
I
i-Bu
nonafluoro-2-butyl
Cl
CF3


15-3582
3-chloro-n-propyl
i-Pr
n-Pr
H
CN
H
H
I
s-Bu
nonafluoro-2-butyl
F
CF3


15-3583
3-bromo-n-propyl
H
H
H
CN
H
H
I
s-Bu
nonafluoro-2-butyl
Cl
CF3


15-3594
2,2-dichloroethyl
H
Et
H
CN
H
H
OCF3
F
heptafluoroisopropyl
F
OCF3


15-3624
2,2,2-trifluoroethyl
H
H
H
CN
H
H
OCF3
Me
nonafluoro-2-butyl
Me
OCF3


15-3737
2,2-dichloroethyl
H
Et
H
CN
H
H
OCF3
F
heptafluoroisopropyl
F
CF3


15-3767
2,2,2-trifluoroethyl
H
H
H
CN
H
H
OCF3
Me
nonafluoro-2-butyl
Me
CF3


15-3880
2,2-dichloroethyl
H
Et
H
CN
H
H
CF3
F
heptafluoroisopropyl
F
CF3


15-3910
2,2,2-trifluoroethyl
H
H
H
CN
H
H
CF3
Me
nonafluoro-2-butyl
Me
CF3


15-4023
2,2-dichloroethyl
H
Et
F
CN
H
H
Cl
F
heptafluoroisopropyl
F
Cl


15-4053
2,2,2-trifluoroethyl
H
H
F
CN
H
H
Cl
Me
nonafluoro-2-butyl
Me
I


15-4166
2,2-dichloroethyl
H
Et
F
CN
H
H
Cl
F
heptafluoroisopropyl
F
OCF3


15-4196
2,2,2-trifluoroethyl
H
H
F
CN
H
H
Cl
Me
nonafluoro-2-butyl
Me
OCF3


15-4304
2-chloroethyl
Me
Me
F
CN
H
H
Cl
H
heptafluoroisopropyl
Cl
CF3


15-4311
2,2,2-trichloroethyl
H
H
F
CN
H
H
Cl
F
heptafluoroisopropyl
Br
CF3


15-4318
1,2-difluoro-2-propyl
H
H
F
CN
H
H
Cl
Br
heptafluoroisopropyl
Cl
CF3


15-4325
i-butyl
H
H
F
CN
H
H
Cl
Me
nonafluoro-2-butyl
H
CF3


15-4326
s-butyl
H
H
F
CN
H
H
Cl
H
nonafluoro-2-butyl
Me
CF3


15-4327
vinyl
i-Pr
H
F
CN
H
H
Cl
Et
nonafluoro-2-butyl
H
CF3


15-4328
benzyl
H
H
F
CN
H
H
Cl
H
nonafluoro-2-butyl
Et
CF3


15-4339
2,2,2-trifluoroethyl
H
H
F
CN
H
H
Cl
Me
nonafluoro-2-butyl
Me
n-C3F7


15-4340
2,2,2-trichloroethyl
H
H
F
CN
H
H
Cl
Me
nonafluoro-2-butyl
Et
i-C3F7


15-4346
i-propyl
H
H
F
CN
H
H
Cl
Et
nonafluoro-2-butyl
Me
n-C3F7


15-4347
1,2-difluoro-2-propyl
H
H
F
CN
H
H
Cl
Et
nonafluoro-2-butyl
Et
i-C3F7


15-4353
2-chloroethyl
H
H
F
CN
H
H
Br
n-Pr
heptafluoroisopropyl
Me
CF3


15-4354
2-bromoethyl
H
H
F
CN
H
H
Br
n-Pr
heptafluoroisopropyl
Et
CF3


15-4360
2,2,2-trichloroethyl
H
H
F
CN
H
H
Br
i-Pr
heptafluoroisopropyl
Me
CF3


15-4361
2,2,2-tribromoethyl
H
H
F
CN
H
H
Br
i-Pr
heptafluoroisopropyl
Et
CF3


15-4367
1,2-difluoro-2-prooyl
H
H
F
CN
H
H
Br
n-Bu
heptafluoroisopropyl
Me
CF3


15-4368
1,3-difluoro-2-propyl
H
H
F
CN
H
H
Br
n-Bu
heptafluoroisopropyl
Et
CF3


15-4374
i-butyl
H
H
F
CN
H
H
Br
i-Bu
nonafluoro-2-butyl
Me
CF3


15-4375
s-butyl
H
H
F
CN
H
H
Br
i-Bu
nonafluoro-2-butyl
Et
CF3


15-4381
2-fluoroethyl
H
H
F
CN
H
H
Br
s-Bu
nonafluoro-2-butyl
Me
CF3


15-4382
2-chloroethyl
H
H
F
CN
H
H
Br
s-Bu
nonafluoro-2-butyl
Et
CF3


15-4388
2,2,2-trifluoroethyl
H
H
F
CN
H
H
Br
F
nonafluoro-2-butyl
Me
CF3


15-4389
2,2,2-trichloroethyl
H
H
F
CN
H
H
Br
F
nonafluoro-2-butyl
Et
CF3


15-4395
i-propyl
Et
i-Pr
F
CN
H
H
Br
Cl
nonafluoro-2-butyl
Me
CF3


15-4396
1,2-difluoro-2-propyl
H
H
F
CN
H
H
Br
Cl
nonafluoro-2-butyl
Et
CF3


15-4402
2-iodoethyl
H
H
F
CN
H
H
I
Br
heptafluoroisopropyl
Me
CF3


15-4403
2-cyanoethyl
H
H
F
CN
H
H
I
Br
heptafluoroisopropyl
Et
CF3


15-4409
n-propyl
n-Pr
Me
F
CN
H
H
I
I
heptafluoroisopropyl
Me
CF3


15-4410
3-fluoro-n-propyl
H
H
F
CN
H
H
I
I
heptafluoroisopropyl
Et
CF3


15-4416
1,3-dichloro-2-propyl
H
H
F
CN
H
H
I
Me
heptafluoroisopropyl
F
C2F5


15-4417
1-chloro-3-fluoro-2-propyl
H
H
F
CN
H
H
I
Me
nonafluoro-2-butyl
Cl
CF3


15-4420
4,4,4-trifluoro-n-butyl
H
H
F
CN
H
H
I
Et
nonafluoro-2-butyl
F
CF3


15-4421
i-butyl
H
H
F
CN
H
H
I
Et
nonafluoro-2-butyl
Cl
CF3


15-4424
benzyl
H
H
F
CN
H
H
I
n-Pr
nonafluoro-2-butyl
F
CF3


15-4425
phenyl
H
H
F
CN
H
H
I
n-Pr
nonafluoro-2-butyl
Cl
CF3


15-4428
2-fluoroethyl
H
H
F
CN
H
H
I
i-Pr
nonafluoro-2-butyl
F
I-C3F7


15-4429
2-chloroethyl
H
H
F
CN
H
H
I
i-Pr
nonafluoro-2-butyl
Cl
CF3


15-4432
2-cyanoethyl
H
H
F
CN
H
H
I
n-Bu
nonafluoro-2-butyl
F
CF3


15-4433
2,2-difluoroethyl
H
H
F
CN
H
H
I
n-Bu
nonafluoro-2-butyl
Cl
CF3


15-4436
2,2,2-trichloroethyl
H
H
F
CN
H
H
I
i-Bu
nonafluoro-2-butyl
F
CF3


15-4437
2,2,2-trichloroethyl
H
H
F
CN
H
H
I
i-Bu
nonafluoro-2-butyl
Cl
CF3


15-4440
3-chloro-n-propyl
i-Pr
n-Pr
F
CN
H
H
I
s-Bu
nonafluoro-2-butyl
F
CF3


15-4441
3-bromo-n-propyl
H
H
F
CN
H
H
I
s-Bu
nonafluoro-2-butyl
Cl
CF3


15-4452
2,2-dichloroethyl
H
Et
F
CN
H
H
OCF3
F
heptafluoroisopropyl
F
OCF3


15-4482
2,2,2-trifluoroethyl
H
H
F
CN
H
H
OCF3
Me
nonafluoro-2-butyl
Me
OCF3


15-4595
2,2-dichloroethyl
H
Et
F
CN
H
H
OCF3
F
heptafluoroisopropyl
F
CF3


15-4625
2,2,2-trifluoroethyl
H
H
F
CN
H
H
OCF3
Me
nonafluoro-2-butyl
Me
CF3


15-4738
2,2-dichloroethyl
H
Et
F
CN
H
H
CF3
F
heptafluoroisopropyl
F
CF3


15-4768
2,2,2-trifluoroethyl
H
H
F
CN
H
H
CF3
Me
nonafluoro-2-butyl
Me
CF3


15-4881
2,2-dichloroethyl
H
Et
F
CN
F
H
Cl
F
heptafluoroisopropyl
F
Cl


15-4911
2,2,2-trifluoroethyl
H
H
F
CN
F
H
Cl
Me
nonafluoro-2-butyl
Me
I


15-5024
2,2-dichloroethyl
H
Et
F
CN
F
H
Cl
F
heptafluoroisopropyl
F
OCF3


15-5054
2,2,2-trifluoroethyl
H
H
F
CN
F
H
Cl
Me
nonafluoro-2-butyl
Me
OCF3


15-5163
2-bromoethyl
H
H
F
CN
F
H
F
Br
heptafluoroisopropyl
H
CF3


15-5168
2,2,2-trifluoroethyl
H
H
F
CN
F
H
Cl
F
heptafluoroisopropyl
Cl
CF3


15-5180
3,3.3-trifluoro-n-propyl
H
H
F
CN
F
H
Cl
I
nonafluoro-2-butyl
Cl
CF3


15-5183
i-butyl
H
H
F
CN
F
H
Cl
Me
nonafluoro-2-butyl
H
CF3


15-5184
s-butyl
H
H
F
CN
F
H
Cl
H
nonafluoro-2-butyl
Me
CF3


15-5185
vinyl
i-Pr
H
F
CN
F
H
Cl
Et
nonafluoro-2-butyl
H
CF3


15-5186
benzyl
H
H
F
CN
F
H
Cl
H
nonafluoro-2-butyl
Et
CF3


15-5197
2,2,2-trifluoroethyl
H
H
F
CN
F
H
Cl
Me
nonafluoro-2-butyl
Me
n-C3F7


15-5198
2,2,2-trichloroethyl
H
H
F
CN
F
H
Cl
Me
nonafluoro-2-butyl
Et
I-C3F7


15-5204
i-propyl
H
H
F
CN
F
H
Cl
Et
nonafluoro-2-butyl
Me
n-C3F7


15-5205
1,2-difluoro-2-propyl
H
H
F
CN
F
H
Cl
Et
nonafluoro-2-butyl
Et
i-C3F7


15-5211
2-chloroethyl
H
H
F
CN
F
H
Br
n-Pr
heptafluoroisopropyl
Me
CF3


15-5212
2-bromoethyl
H
H
F
CN
F
H
Br
n-Pr
heptafluoroisopropyl
Et
CF3


15-5218
2,2,2-trichloroethyl
H
H
F
CN
F
H
Br
i-Pr
heptafluoroisopropyl
Me
CF3


15-5219
2,2,2-tribromoethyl
H
H
F
CN
F
H
Br
i-Pr
heptafluoroisopropyl
Et
CF3


15-5225
1,2-difluoro-2-propyl
H
H
F
CN
F
H
Br
n-Bu
heptafluoroisopropyl
Me
CF3


15-5226
1,3-difluoro-2-propyl
H
H
F
CN
F
H
Br
n-Bu
heptafluoroisopropyl
Et
CF3


15-5232
i-butyl
H
H
F
CN
F
H
Br
i-Bu
nonafluoro-2-butyl
Me
CF3


15-5233
s-butyl
H
H
F
CN
F
H
Br
i-Bu
nonafluoro-2-butyl
Et
CF3


15-5239
2-fluomethyl
H
H
F
CN
F
H
Br
s-Bu
nonafluoro-2-butyl
Me
CF3


15-5240
2-chloroethyl
H
H
F
CN
F
H
Br
s-Bu
nonafluoro-2-butyl
Et
CF3


15-5246
2,2,2-trifluoroethyl
H
H
F
CN
F
H
Br
F
nonafluoro-2-butyl
Me
CF3


15-5247
2,2,2-trichloroethyl
H
H
F
CN
F
H
Br
F
nonafluoro-2-butyl
Et
CF3


15-5253
i-propyl
Et
i-Pr
F
CN
F
H
Br
Cl
nonafluoro-2-butyl
Me
CF3


15-5254
1,2-difluoro-2-propyl
H
H
F
CN
F
H
Br
Cl
nonafluoro-2-butyl
Et
CF3


15-5260
2-iodoethyl
H
H
F
CN
F
H
I
Br
heptafluoroisopropyl
Me
CF3


15-5261
2-cyanoethyl
H
H
F
CN
F
H
I
Br
heptafluoroisopropyl
Et
CF3


15-5267
n-propyl
n-Pr
Me
F
CN
F
H
I
I
heptafluoroisopropyl
Me
CF3


15-5268
3-fluoro-n-propyl
H
H
F
CN
F
H
I
I
heptafluoroisopropyl
Et
CF3


15-5274
1,3-dichloro-2-propyl
H
H
F
CN
F
H
I
Me
heptafluoroisopropyl
F
C2F5


15-5275
1-chloro-3-fluoro-2-propyl
H
H
F
CN
F
H
I
Me
nonafluoro-2-butyl
Cl
CF3


15-5278
4,4,4-trifluoro-n-butyl
H
H
F
CN
F
H
I
Et
nonafluoro-2-butyl
F
CF3


15-5279
i-butyl
H
H
F
CN
F
H
I
Et
nonafluoro-2-butyl
Cl
CF3


15-5282
benzyl
H
H
F
CN
F
H
I
n-Pr
nonafluoro-2-butyl
F
CF3


15-5283
phenyl
H
H
F
CN
F
H
I
n-Pr
nonafluoro-2-butyl
Cl
CF3


15-5286
2-fluoroethyl
H
H
F
CN
F
H
I
i-Pr
nonafluoro-2-butyl
F
i-C3F7


15-5287
2-chloroethyl
H
H
F
CN
F
H
I
i-Pr
nonafluoro-2-butyl
Cl
CF3


15-5290
2-cyanoethyl
H
H
F
CN
F
H
I
n-Bu
nonafluoro-2-butyl
F
CF3


15-5291
2,2-difluoroethyl
H
H
F
CN
F
H
I
n-Bu
nonafluoro-2-butyl
Cl
CF3


15-5294
2,2,2-trichloroethyl
H
H
F
CN
F
H
I
i-Bu
nonafluoro-2-butyl
F
CF3


15-5295
2,2,2-tribromoethyl
H
H
F
CN
F
H
I
i-Bu
nonafluoro-2-butyl
Cl
CF3


15-5298
3-chloro-n-propyl
i-Pr
n-Pr
F
CN
F
H
I
s-Bu
nonafluoro-2-butyl
F
CF3


15-5299
3-bromo-n-propyl
H
H
F
CN
F
H
I
s-Bu
nonafluoro-2-butyl
Cl
CF3


15-5310
2,2-dichloroethyl
H
Et
F
CN
F
H
OCF3
F
heptafluoroisopropyl
F
OCF3


15-5340
2,2,2-trifluoroethyl
H
H
F
CN
F
H
OCF3
Me
nonafluoro-2-butyl
Me
OCF3


15-5453
2,2-dichloroethyl
H
Et
F
CN
F
H
OCF3
F
heptafluoroisopropyl
F
CF3


15-5483
2,2,2-trifluoroethyl
H
H
F
CN
F
H
OCF3
Me
nonafluoro-2-butyl
Me
CF3


15-5596
2,2-dichloroethyl
H
Et
F
CN
F
H
CF3
F
heptafluoroisopropyl
F
CF3


15-5626
2,2,2-trifluoroethyl
H
H
F
CN
F
H
CF3
Me
nonafluoro-2-butyl
Me
CF3











embedded image





















TABLE 16





compound














number
Q1
R1
R2
A
X2
X3
X4
Y1
Y2
Y3
Y4
Y5







16-1
phenyl
H
H
N
H
H
H
F
H
heptafluoroisopropyl
H
F


16-2
3-cyanophenyl
H
H
N
H
H
H
F
H
heptafluoroisopropyl
H
F


16-3
4-cyanophenyl
H
H
N
H
H
H
F
H
heptafluoroisopropyl
H
F


16-4
2-chloropyridin-3-yl
H
H
N
H
H
H
F
H
heptafluoroisopropyl
H
F


16-5
phenyl
H
H
N
H
H
H
F
H
nonafluoro-2-butyl
H
F


16-6
3-cyanophenyl
H
H
N
H
H
H
F
H
nonafluoro-2-butyl
H
F


16-7
4-cyanophenyl
H
H
N
H
H
H
F
H
nonafluoro-2-butyl
H
F


16-8
2-chloropyridin-3-yl
H
H
N
H
H
H
F
H
nonafluoro-2-butyl
H
F


16-9
phenyl
H
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


16-13
2-chlorophenyl
H
H
N
H
H
H
F
H
heptafluoroisopropyl
H
Cl


16-17
3-bromophenyl
H
H
N
H
H
H
F
H
heptafluoroisopropyl
H
Br


16-20
3-iodophenyl
H
H
N
H
H
H
Cl
H
pentafluoroethyl
H
Cl


16-22
(2-trifluoromethyl)phenyl
H
H
N
H
H
H
F
H
heptafluoroisopropyl
H
I


16-25
2-nitrophenyl
H
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
Br


16-28
2-cyanophenyl
H
H
N
H
H
H
Cl
H
pentafluoroethyl
H
Cl


16-29
3-cyanophenyl
H
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


16-30
4-cyanophenyl
H
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


16-31
2,6-difluorophenyl
H
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
I


16-43
pyridin-3-yl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
I


16-44
2-fluoropyridin-3-yl
H
H
N
H
H
H
Cl
H
pentafluoroethyl
H
Cl


16-45
2-chloropyridin-3-yl
H
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


16-63
5-nitropyridin-3-yl
H
H
N
H
H
H
Cl
H
pentafluoroethyl
H
Cl


16-64
5-cyanopyridin-3-yl
H
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


16-66
4-chloropyridin-3-yl
H
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


16-86
4-cyanopyridin-2-yl
H
H
N
H
H
H
Cl
H
pentafluoroethyl
H
Cl


16-87
phenyl
H
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


16-107
3-cyanophenyl
H
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


16-108
4-cyanophenyl
H
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


16-123
2-chloropyridin-3-yl
H
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


16-165
phenyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
Br


16-166
2-fluorophenyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
Br


16-177
4-iodophenyl
H
H
N
H
H
H
Br
H
pentafluoroethyl
H
Br


16-185
3-cyanophenyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
Br


16-186
4-cyanophenyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
Br


16-200
2-fluoropyridin-3-yl
H
H
N
H
H
H
Br
H
pentafluoroethyl
H
Br


16-201
2-chloropyridin-3-yl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
Br


16-219
5-nitropyridin-3-yl
H
H
N
H
H
H
Br
H
pentafluoroethyl
H
Br


16-220
5-cyanopyridin-3-yl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
Br


16-221
4-fluoropyridin-3-yl
H
H
N
H
H
H
Br
H
pentafluoroethyl
H
Br


16-242
4-cyanopyridin-2-yl
H
H
N
H
H
H
Br
H
pentafluoroethyl
H
Br


16-243
phenyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


16-244
2-fluorophenyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


16-263
3-cyanophenyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


16-264
4-cyanophenyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


16-279
2-chloropyridin-3-yl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


16-321
phenyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
I


16-328
2-bromophenyl
H
H
N
H
H
H
I
H
pentafluoroethyl
H
I


16-341
3-cyanophenyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
I


16-342
4-cyanophenyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
I


16-356
2-fluoropyridin-3-yl
H
H
N
H
H
H
I
H
pentafluoroethyl
H
I


16-357
2-chloropyridin-3-yl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
I


16-375
5-nitropyridin-3-yl
H
H
N
H
H
H
I
H
pentafluoroethyl
H
I


16-399
phenyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
I


16-400
2-fluorophenyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
I


16-419
3-cyanophenyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
I


16-420
4-cyanophenyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
I


16-435
2-chloropyridin-3-yl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
I


16-477
phenyl
H
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


16-478
2-fluorophenyl
H
H
N
H
H
H
Cl
H
pentafluoroethyl
H
OCF3


16-492
(4-trifluoromethyl)phenyl
H
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
OC2F5


16-493
2-nitrophenyl
H
H
N
H
H
H
F
H
heptafluoroisopropyl
H
OCF3


16-496
2-cyanophenyl
H
H
N
H
H
H
Cl
H
pentafluoroethyl
H
OC2F5


16-497
3-cyanophenyl
H
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


16-498
4-cyanophenyl
H
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


16-504
4-bromo-2-chlorophenyl
H
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
OC2F5


16-512
2-fluoropyridin-3-yl
H
H
N
H
H
H
Cl
H
pentafluoroethyl
H
OCF3


16-513
2-chloropyridin-3-yl
H
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


16-555
phenyl
H
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


16-565
2-iodophenyl
H
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


16-571
2-nitrophenyl
H
H
N
H
H
H
F
H
nonafluoro-2-butyl
H
OCF3


16-572
3-nitrophenyl
H
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


16-573
4-nitrophenyl
H
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


16-581
2-chloro-4,5-difluorophenyl
H
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
OC2F5


16-591
2-chloropyridin-3-yl
H
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


16-597
6-fluoropyridin-3-yl
H
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
OC2F5


16-633
phenyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


16-646
(2-trifluoromethyl)phenyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


16-653
3-cyanophenyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


16-654
4-cyanophenyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


16-669
2-chloropyridin-3-yl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


16-676
6-chloropyridin-3-yl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


16-711
phenyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


16-731
3-cyanophenyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


16-732
4-cyanophenyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


16-745
pyridin-3-yl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


16-747
2-chloropyridin-3-yl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


16-789
phenyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


16-794
3-chlorophenyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


16-809
3-cyanophenyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


16-810
4-cyanophenyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


16-825
2-chloropyridin-3-yl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


16-867
phenyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


16-887
3-cyanophenyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


16-888
4-cyanophenyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


16-903
2-chloropyridin-3-yl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


16-945
phenyl
H
H
N
H
H
H
F
H
heptafluoroisopropyl
H
CF3


16-946
phenyl
H
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


16-947
2-fluorophenyl
H
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


16-958
4-iodophenyl
H
H
N
H
H
H
Cl
H
pentafluoroethyl
H
CF3


16-965
2-cyanophenyl
H
H
N
H
H
H
Cl
H
pentafluoroethyl
H
C2F5


16-966
3-cyanophenyl
H
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


16-967
4-cyanophenyl
H
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


16-970
2,4-dichlorophenyl
H
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
C2F5


16-974
2-bromo-4-chlorophenyl
H
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


16-981
2-fluoropyridin-3-yl
H
H
N
H
H
H
Cl
H
pentafluoroethyl
H
CF3


16-982
2-chloropyridin-3-yl
H
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


16-995
5-fluoropyridin-3-yl
H
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
C2F5


16-997
5-bromopyridin-3-yl
H
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


16-998
5-iodopyridin-3-yl
H
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
i-C3F7


16-1000
5-nitropyridin-3-yl
H
H
N
H
H
H
Cl
H
pentafluoroethyl
H
CF3


16-1002
4-fluoropyridin-3-yl
H
H
N
H
H
H
Cl
H
pentafluoroethyl
H
CF3


16-1004
4-bromopyridin-3-yl
H
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


16-1023
4-cyanopyridin-2-yl
H
H
N
H
H
H
Cl
H
pentafluoroethyl
H
CF3


16-1024
phenyl
H
H
N
H
H
H
F
H
nonafluoro-2-butyl
H
CF3


16-1025
phenyl
H
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


16-1038
(2-trifluoromethyl)phenyl
H
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


16-1045
3-cyanophenyl
H
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


16-1046
4-cyanophenyl
H
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


16-1055
2-chloro-4-nitrophenyl
H
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


16-1061
2-chloropyridin-3-yl
H
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


16-1074
5-fluoropyridin-3-yl
H
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


16-1076
5-bromopyridin-3-yl
H
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
n-C3F7


16-1077
5-iodopyridin-3-yl
H
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


16-1081
4-fluoropyridin-3-yl
H
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


16-1085
4-(trifluoromethyl)pyridin-3-yl
H
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
n-C3F7


16-1086
4-nitropyridin-3-yl
H
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


16-1102
4-cyanopyridin-2-yl
H
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


16-1103
phenyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1104
2-fluorophenyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1105
3-fluorophenyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1106
4-fluorophenyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1107
2-chlorophenyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1108
3-chlorophenyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1109
4-chlorophenyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1110
2-bromophenyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1111
3-bromophenyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1112
4-bromophenyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1113
2-iodophenyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1114
3-iodophenyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1115
4-iodophenyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1116
(2-trifluoromethyl)phenyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1117
(3-trifluoromethyl)phenyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1118
(4-trifluoromethyl)phenyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1119
2-nitrophenyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1120
3-nitrophenyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1121
4-nitrophenyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1122
2-cyanophenyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1123
3-cyanophenyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1124
4-cyanophenyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1125
2,6-difluorophenyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1126
3,4-dichlorophenyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1127
2,4-dichlorophenyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1128
2-chloro-4-fluorophenyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1129
2-chloro-4,5-difluorophenyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1130
4-bromo-2-chlorophenyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1131
2-bromo-4-chlorophenyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1132
2-bromo-4-fluorophenyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1133
2-chloro-4-nitrophenyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1134
3,5-dicyanophenyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1135
4-cyano-2-fluorophenyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1136
2-chloro-4-cyanophenyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1137
pyridin-3-yl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1138
2-fluoropyridin-3-yl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1139
2-chloropyridin-3-yl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1140
2-bromopyridin-3-yl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1141
2-iodopyridin-3-yl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1142
2-(trifluoromethyl)pyridin-3-yl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1143
2-nitropyridin-3-yl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1144
2-cyanopyridin-3-yl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1145
6-fluoropyridin-3-yl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1146
6-chloropyridin-3-yl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1147
6-bromopyridin-3-yl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1148
6-iodopyridin-3-yl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1149
6-(trifluoromethyl)pyridin-3-yl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1150
6-nitropyridin-3-yl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1151
6-cyanopyridin-3-yl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1152
5-fluoropyridin-3-yl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1153
5-chloropyridin-3-yl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1164
5-bromopyridin-3-yl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1155
5-iodopyridin-3-yl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1156
5-(trifluoromethyl)pyridin-3-yl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1157
5-nitropyridin-3-yl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1158
5-cyanopyridin-3-yl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1159
4-fluoropyridin-3-yl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1160
4-chloropyridin-3-yl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1161
4-bromopyridin-3-yl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1162
4-iodopyridin-3-yl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1163
4-(trifluoromethyl)pyridin-3-yl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1164
4-nitropyridin-3-yl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1165
4-cyanopyridin-3-yl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1166
2,6-dichloropyridin-3-yl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1167
pyridin-3-yl N-oxide
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1168
pyridin-4-yl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1169
2-chloropyridin-4-yl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1170
3-bromopyridin-4-yl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1171
3,5-dichloropyridin-4-yl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1172
3-(trifluoromethyl)pyridin-4-yl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1173
2,6-dicyanopyridin-4-yl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1174
pyridin-4-yl N-oxide
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1175
pyridin-2-yl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1176
3-chloropyridin-2-yl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1177
4-bromopyridin-2-yl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1178
5-iodopyridin-2-yl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1179
6-chloropyridin-2-yl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1180
4-cyanopyridin-2-yl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-1181
phenyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1182
2-fluorophenyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1183
3-fluorophenyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1184
4-fluorophenyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1185
2-chlorophenyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1186
3-chlorophenyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1187
4-chlorophenyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1188
2-bromophenyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1189
3-bromophenyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1190
4-bromophenyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1191
2-iodophenyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1192
3-iodophenyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1193
4-iodophenyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1194
(2-trifluoromethyl)phenyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1195
(3-trifluoromethyl)phenyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1196
(4-trifluoromethyl)phenyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1197
2-nitrophenyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1198
3-nitrophenyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1199
4-nitrophenyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1200
2-cyanophenyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1201
3-cyanophenyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1202
4-cyanophenyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1203
2,6-difluorophenyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1204
3,4-dichlorophenyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1205
2,4-dichlorophenyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1206
2-chloro-4-fluorophenyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1207
2-chloro-4,5-difluorophenyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1208
4-bromo-2-chlorophenyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1209
2-bromo-4-chlorophenyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1210
2-bromo-4-fluorophenyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1211
2-chloro-4-nitrophenyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1212
3,5-dicyanophenyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1213
4-cyano-2-fluorophenyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1214
2-chloro-4-cyanophenyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1215
pyridin-3-yl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1216
2-fluoropyridin-3-yl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1217
2-chloropyridin-3-yl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1218
2-bromopyridin-3-yl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1219
2-iodopyridin-3-yl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1220
2-(trifluoromethyl)pyridin-3-yl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1221
2-nitropyridin-3-yl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1222
2-cyanopyridin-3-yl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1223
6-fluoropyridin-3-yl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1224
6-chloropyridin-3-yl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1225
6-bromopyridin-3-yl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1226
6-iodopyridin-3-yl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1227
6-(trifluoromethyl)pyridin-3-yl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1228
6-nitropyridin-3-yl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1229
6-cyanopyridin-3-yl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1230
5-fluoropyridin-3-yl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1231
5-chloropyridin-3-yl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1232
5-bromopyridin-3-yl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1233
5-iodopyridin-3-yl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1234
5-(trifluoromethyl)pyridin-3-yl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1235
5-nitropyridin-3-yl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1236
5-cyanopyridin-3-yl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1237
4-fluoropyridin-3-yl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1238
4-chloropyridin-3-yl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1239
4-bromopyridin-3-yl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1240
4-iodopyridin-3-yl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1241
4-(trifluoromethyl)pyridin-3-yl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1242
4-nitropyridin-3-yl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1243
4-cyanopyridin-3-yl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1244
2,6-dichloropyridin-3-yl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1245
pyridin-3-yl N-oxide
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1246
pyridin-4-yl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1247
2-chloropyridin-4-yl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1248
3-bromopyridin-4-yl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1249
3,5-dichloropyridin-4-yl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1250
3-(trifluoromethyl)pyridin-4-yl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1251
2,6-dicyanopyridin-4-yl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1252
pyridin-4-yl N-oxide
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1253
pyridin-2-yl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1254
3-chloropyridin-2-yl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1255
4-bromopyridin-2-yl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1256
5-iodopyridin-2-yl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1257
6-chloropyridin-2-yl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1258
4-cyanopyridin-2-yl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-1259
phenyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1260
2-fluorophenyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1261
3-fluorophenyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1262
4-fluorophenyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1263
2-chlorophenyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1264
3-chlorophenyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1265
4-chlorophenyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1266
2-bromophenyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1267
3-bromophenyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1268
4-bromophenyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1269
2-iodophenyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1270
3-iodophenyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1271
4-iodophenyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1272
(2-trifluoromethyl)phenyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1273
(3-trifluoromethyl)phenyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1274
(4-trifluoromethyl)phenyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1275
2-nitrophenyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1276
3-nitrophenyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1277
4-nitrophenyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1278
2-cyanophenyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1279
3-cyanophenyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1280
4-cyanophenyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1281
2,6-difluorophenyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1282
3,4-dichlorophenyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1283
2,4-dichlorophenyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1284
2-chloro-4-fluorophenyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1285
2-chloro-4,5-difluorophenyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1286
4-bromo-2-chlorophenyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1287
2-bromo-4-chlorophenyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1288
2-bromo-4-fluorophenyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1289
2-chloro-4-nitrophenyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1290
3,5-dicyanophenyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1291
4-cyano-2-fluorophenyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1292
2-chloro-4-cyanophenyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1293
pyridin-3-yl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1294
2-fluoropyridin-3-yl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1295
2-chloropyridin-3-yl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1296
2-bromopyridin-3-yl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1297
2-iodopyridin-3-yl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1298
2-(trifluoromethyl)pyridin-3-yl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1299
2-nitropyridin-3-yl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1300
2-cyanopyridin-3-yl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1301
6-fluoropyridin-3-yl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1302
6-chloropyridin-3-yl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1303
6-bromopyridin-3-yl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1304
6-iodopyridin-3-yl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1305
6-(trifluoromethyl)pyridin-3-yl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1306
6-nitropyridin-3-yl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1307
6-cyanopyridin-3-yl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1308
5-fluoropyridin-3-yl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1309
5-chloropyridin-3-yl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1310
5-bromopyridin-3-yl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1311
5-iodopyridin-3-yl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1312
5-(trifluoromethyl)pyridin-3-yl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1313
5-nitropyridin-3-yl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1314
5-cyanopyridin-3-yl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1315
4-fluoropyridin-3-yl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1316
4-chloropyridin-3-yl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1317
4-bromopyridin-3-yl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1318
4-iodopyridin-3-yl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1319
4-(trifluoromethyl)pyridin-3-yl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1320
4-nitropyridin-3-yl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1321
4-cyanopyridin-3-yl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1322
2,6-dichloropyridin-3-yl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1323
pyridin-3-yl N-oxide
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1324
pyridin-4-yl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1325
2-chloropyridin-4-yl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1326
3-bromopyridin-4-yl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1327
3,5-dichloropyridin-4-yl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1328
3-(trifluoromethyl)pyridin-4-yl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1329
2,6-dicyanopyridin-4-yl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1330
pyridin-4-yl N-oxide
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1331
pyridin-2-yl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1332
3-chloropyridin-2-yl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1333
4-bromopyridin-2-yl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1334
5-iodopyridin-2-yl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1335
6-chloropyridin-2-yl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1336
4-cyanopyridin-2-yl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-1337
phenyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1338
2-fluorophenyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1339
3-fluorophenyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1340
4-fluorophenyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1341
2-chlorophenyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1342
3-chlorophenyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1343
4-chlorophenyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1344
2-bromophenyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1345
3-bromophenyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1346
4-bromophenyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1347
2-iodophenyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1348
3-iodophenyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1349
4-iodophenyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1350
(2-trifluoromethyl)phenyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1351
(3-trifluoromethyl)phenyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1352
(4-trifluoromethyl)phenyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1353
2-nitrophenyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1354
3-nitrophenyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1355
4-nitrophenyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1356
2-cyanophenyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1357
3-cyanophenyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1358
4-cyanophenyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1359
2,6-difluorophenyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1360
3,4-dichlorophenyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1361
2,4-dichlorophenyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1362
2-chloro-4-fluorophenyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1363
2-chloro-4,5-difluorophenyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1364
4-bromo-2-chlorophenyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1365
2-bromo-4-chlorophenyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1366
2-bromo-4-fluorophenyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1367
2-chloro-4-nitrophenyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1368
3,5-dicyanophenyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1369
4-cyano-2-fluorophenyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1370
2-chloro-4-cyanophenyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1371
pyridin-3-yl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1372
2-fluoropyridin-3-yl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1373
2-chloropyridin-3-yl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1374
2-bromopyridin-3-yl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1375
2-iodopyridin-3-yl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1376
2-(trifluoromethyl)pyridin-3-yl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1377
2-nitropyridin-3-yl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1378
2-cyanopyridin-3-yl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1379
6-fluoropyridin-3-yl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1380
6-chloropyridin-3-yl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1381
6-bromopyridin-3-yl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1382
6-iodopyridin-3-yl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1383
6-(trifluoromethyl)pyridin-3-yl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1384
6-nitropyridin-3-yl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1385
6-cyanopyridin-3-yl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1386
5-fluoropyridin-3-yl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1387
5-chloropyridin-3-yl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1388
5-bromopyridin-3-yl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1389
5-iodopyridin-3-yl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1390
5-(trifluoromethyl)pyridin-3-yl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1391
5-nitropyridin-3-yl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1392
5-cyanopyridin-3-yl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1393
4-fluoropyridin-3-yl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1394
4-chloropyridin-3-yl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1395
4-bromopyridin-3-yl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1396
4-iodopyridin-3-yl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1397
4-(trifluoromethyl)pyridin-3-yl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1398
4-nitropyridin-3-yl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1399
4-cyanopyridin-3-yl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1400
2,6-dichloropyridin-3-yl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1401
pyridin-3-yl N-oxide
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1402
pyridin-4-yl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1403
2-chloropyridin-4-yl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1404
3-bromopyridin-4-yl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1405
3,5-dichloropyridin-4-yl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1406
3-(trifluoromethyl)pyridin-4-yl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1407
2,6-dichloropyridin-4-yl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1408
pyridin-4-yl N-oxide
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1409
pyridin-2-yl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1410
3-chloropyridin-2-yl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1411
4-bromopyridin-2-yl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1412
5-iodopyridin-2-yl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1413
6-chloropyridin-2-yl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1414
4-cyanopyridin-2-yl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-1415
phenyl
H
H
N
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


16-1422
2-bromophenyl
H
H
N
H
H
H
OCF3
H
heptafluoroisopropyl
H
OC2F5


16-1427
4-iodophenyl
H
H
N
H
H
H
OCF3
H
pentafluoroethyl
H
OCF3


16-1430
3-cyanophenyl
H
H
N
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


16-1431
4-cyanophenyl
H
H
N
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


16-1436
2-chloro-4,5-difluorophenyl
H
H
N
H
H
H
OC2F5
H
heptafluoroisopropyl
H
OC2F5


16-1439
2-bromo-4-fluorophenyl
H
H
N
H
H
H
OC2F5
H
heptafluoroisopropyl
H
OCF3


16-1445
2-fluoropyridin-3-yl
H
H
N
H
H
H
OCF3
H
pentafluoroethyl
H
OCF3


16-1446
2-chloropyridin-3-yl
H
H
N
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


16-1471
phenyl
H
H
N
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


16-1478
2-bromophenyl
H
H
N
H
H
H
OC2F5
H
nonafluoro-2-butyl
H
OCF3


16-1484
(2-trifluoromethyl)phenyl
H
H
N
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OC2F5


16-1486
3-cyanophenyl
H
H
N
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


16-1487
4-cyanophenyl
H
H
N
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


16-1493
4-bromo-2-chlorophenyl
H
H
N
H
H
H
OC2F5
H
nonafluoro-2-butyl
H
OC2F5


16-1502
2-chloropyridin-3-yl
H
H
N
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


16-1527
phenyl
H
H
N
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


16-1534
2-bromophenyl
H
H
N
H
H
H
CF3
H
heptafluoroisopropyl
H
OC2F5


16-1539
4-iodophenyl
H
H
N
H
H
H
CF3
H
pentafluoroethyl
H
OCF3


16-1540
(2-trifluoromethyl)phenyl
H
H
N
H
H
H
C2F5
H
heptafluoroisopropyl
H
OC2F5


16-1542
3-cyanophenyl
H
H
N
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


16-1543
4-cyanophenyl
H
H
N
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


16-1550
2-bromo-4-chlorophenyl
H
H
N
H
H
H
n-C3F7
H
heptafluoroisopropyl
H
OCF3


16-1554
4-cyano-2-fluorophenyl
H
H
N
H
H
H
i-C3F7
H
heptafluoroisopropyl
H
OCF3


16-1558
2-chloropyridin-3-yl
H
H
N
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


16-1564
6-chloropyridin-3-yl
H
H
N
H
H
H
n-C3F7
H
heptafluoroisopropyl
H
OC2F5


16-1567
5-cyanopyridin-3-yl
H
H
N
H
H
H
i-C3F7
H
heptafluoroisopropyl
H
OC2F5


16-1568
4-chloropyridin-3-yl
H
H
N
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


16-1583
phenyl
H
H
N
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


16-1594
3-iodophenyl
H
H
N
H
H
H
CF3
H
nonafluoro-2-butyl
H
OC2F5


16-1597
3-nitrophenyl
H
H
N
H
H
H
C2F5
H
nonafluoro-2-butyl
H
OCF3


16-1598
3-cyanophenyl
H
H
N
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


16-1599
4-cyanophenyl
H
H
N
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


16-1605
4-bromo-2-chlorophenyl
H
H
N
H
H
H
i-C3F7
H
nonafluoro-2-butyl
H
OCF3


16-1608
2-chloro-4-nitrophenyl
H
H
N
H
H
H
n-C3F7
H
nonafluoro-2-butyl
H
OCF3


16-1614
2-chloropyridin-3-yl
H
H
N
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


16-1615
2-bromopyridin-3-yl
H
H
N
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


16-1616
2-iodopyridin-3-yl
H
H
N
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


16-1617
2-(trifluoromethyl)pyridin-3-yl
H
H
N
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


16-1618
2-nitropyridin-3-yl
H
H
N
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


16-1619
2-cyanopyridin-3-yl
H
H
N
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


16-1620
6-chloropyridin-3-yl
H
H
N
H
H
H
C2F5
H
nonafluoro-2-butyl
H
OC2F5


16-1625
4-cyanopyridin-3-yl
H
H
N
H
H
H
n-C3F7
H
nonafluoro-2-butyl
H
OC2F5


16-1636
5-iodopyridin-2-yl
H
H
N
H
H
H
i-C3F7
H
nonafluoro-2-butyl
H
OC2F5


16-1639
phenyl
H
H
N
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


16-1640
2-fluorophenyl
H
H
N
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


16-1651
4-iodophenyl
H
H
N
H
H
H
CF3
H
pentafluoroethyl
H
CF3


16-1653
(3-trifluoromethyl)phenyl
H
H
N
H
H
H
C2F5
H
heptafluoroisopropyl
H
CF3


16-1658
2-cyanophenyl
H
H
N
H
H
H
CF3
H
pentafluoroethyl
H
CF3


16-1659
3-cyanophenyl
H
H
N
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


16-1660
4-cyanophenyl
H
H
N
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


16-1666
4-bromo-2-chlorophenyl
H
H
N
H
H
H
n-C3F7
H
heptafluoroisopropyl
H
CF3


16-1671
4-cyano-2-fluorophenyl
H
H
N
H
H
H
i-C3F7
H
heptafluoroisopropyl
H
CF3


16-1675
2-chloropyridin-3-yl
H
H
N
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


16-1676
2-bromopyridin-3-yl
H
H
N
H
H
H
C2F5
H
heptafluoroisopropyl
H
C2F5


16-1677
2-iodopyridin-3-yl
H
H
N
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


16-1678
2-(trifluoromethyl)pyridin-3-yl
H
H
N
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


16-1679
2-nitropyridin-3-yl
H
H
N
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


16-1680
2-cyanopyridin-3-yl
H
H
N
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


16-1681
6-fluoropyridin-3-yl
H
H
N
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


16-1682
6-chloropyridin-3-yl
H
H
N
H
H
H
C2F5
H
heptafluoroisopropyl
H
n-C3F7


16-1691
4-cyanopyridin-3-yl
H
H
N
H
H
H
C2F5
H
heptafluoroisopropyl
H
i-C3F7


16-1707
phenyl
H
H
N
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


16-1708
2-fluorophenyl
H
H
N
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


16-1719
4-iodophenyl
H
H
N
H
H
H
C2F5
H
nonafluoro-2-butyl
H
CF3


16-1727
3-cyanophenyl
H
H
N
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


16-1728
4-cyanophenyl
H
H
N
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


16-1734
4-bromo-2-chlorophenyl
H
H
N
H
H
H
n-C3F7
H
nonafluoro-2-butyl
H
CF3


16-1739
4-cyano-2-fluorophenyl
H
H
N
H
H
H
i-C3F7
H
nonafluoro-2-butyl
H
CF3


16-1743
2-chloropyridin-3-yl
H
H
N
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


16-1744
2-bromopyridin-3-yl
H
H
N
H
H
H
C2F5
H
nonafluoro-2-butyl
H
C2F5


16-1755
6-cyanopyridin-3-yl
H
H
N
H
H
H
C2F5
H
nonafluoro-2-butyl
H
n-C3F7


16-1759
4-cyanopyridin-3-yl
H
H
N
H
H
H
C2F5
H
nonafluoro-2-butyl
H
i-C3F7


16-1775
phenyl
H
H
N-oxide
H
H
H
F
H
heptafluoroisopropyl
H
F


16-1776
3-cyanophenyl
H
H
N-oxide
H
H
H
F
H
heptafluoroisopropyl
H
F


16-1777
4-cyanophenyl
H
H
N-oxide
H
H
H
F
H
heptafluoroisopropyl
H
F


16-1778
2-chloropyridin-3-yl
H
H
N-oxide
H
H
H
F
H
heptafluoroisopropyl
H
F


16-1779
phenyl
H
H
N-oxide
H
H
H
F
H
nonafluoro-2-butyl
H
F


16-1780
3-cyanophenyl
H
H
N-oxide
H
H
H
F
H
nonafluoro-2-butyl
H
F


16-1781
4-cyanophenyl
H
H
N-oxide
H
H
H
F
H
nonafluoro-2-butyl
H
F


16-1782
2-chloropyridin-3-yl
H
H
N-oxide
H
H
H
F
H
nonafluoro-2-butyl
H
F


16-1783
phenyl
H
H
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


16-1787
2-chlorophenyl
H
H
N-oxide
H
H
H
F
H
heptafluoroisopropyl
H
Cl


16-1791
3-bromophenyl
H
H
N-oxide
H
H
H
F
H
heptafluoroisopropyl
H
Br


16-1795
4-iodophenyl
H
H
N-oxide
H
H
H
Cl
H
pentafluoroethyl
H
Cl


16-1796
(2-trifluoromethyl)phenyl
H
H
N-oxide
H
H
H
F
H
heptafluoroisopropyl
H
I


16-1799
2-nitrophenyl
H
H
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
Br


16-1803
3-cyanophenyl
H
H
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


16-1804
4-cyanophenyl
H
H
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


16-1805
2,6-difluorophenyl
H
H
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
I


16-1817
pyridin-3-yl
H
H
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
I


16-1818
2-fluoropyridin-3-yl
H
H
N-oxide
H
H
H
Cl
H
pentafluoroethyl
H
Cl


16-1819
2-chloropyridin-3-yl
H
H
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


16-1861
phenyl
H
H
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


16-1881
3-cyanophenyl
H
H
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


16-1882
4-cyanophenyl
H
H
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


16-1897
2-chloropyridin-3-yl
H
H
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


16-1939
phenyl
H
H
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
Br


16-1951
4-iodophenyl
H
H
N-oxide
H
H
H
Br
H
pentafluoroethyl
H
Br


16-1959
3-cyanophenyl
H
H
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
Br


16-1960
4-cyanophenyl
H
H
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
Br


16-1973
pyridin-3-yl
H
H
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
Br


16-1975
2-chloropyridin-3-yl
H
H
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
Br


16-1982
6-chloropyridin-3-yl
H
H
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
Br


16-2017
phenyl
H
H
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


16-2037
3-cyanophenyl
H
H
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


16-2038
4-cyanophenyl
H
H
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


16-2053
2-chloropyridin-3-yl
H
H
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


16-2095
phenyl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
I


16-2107
4-iodophenyl
H
H
N-oxide
H
H
H
I
H
pentafluoroethyl
H
I


16-2115
3-cyanophenyl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
I


16-2116
4-cyanophenyl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
I


16-2131
2-chloropyridin-3-yl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
I


16-2160
pyridin-4-yl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
I


16-2173
phenyl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
I


16-2193
3-cyanophenyl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
I


16-2194
4-cyanophenyl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
I


16-2209
2-chloropyridin-3-yl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
I


16-2251
phenyl
H
H
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


16-2263
4-iodophenyl
H
H
N-oxide
H
H
H
Cl
H
pentafluoroethyl
H
OCF3


16-2266
(4-trifluoromethyl)phenyl
H
H
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
OC2F5


16-2267
2-nitrophenyl
H
H
N-oxide
H
H
H
F
H
heptafluoroisopropyl
H
OCF3


16-2270
2-cyanophenyl
H
H
N-oxide
H
H
H
Cl
H
pentafluoroethyl
H
OC2F5


16-2271
3-cyanophenyl
H
H
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


16-2272
4-cyanophenyl
H
H
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


16-2287
2-chloropyridin-3-yl
H
H
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


16-2329
phenyl
H
H
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


16-2345
2-nitrophenyl
H
H
N-oxide
H
H
H
F
H
nonafluoro-2-butyl
H
OCF3


16-2349
3-cyanophenyl
H
H
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


16-2350
4-cyanophenyl
H
H
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


16-2365
2-chloropyridin-3-yl
H
H
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


16-2407
phenyl
H
H
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


16-2427
3-cyanophenyl
H
H
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


16-2428
4-cyanophenyl
H
H
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


16-2444
2-bromopyridin-3-yl
H
H
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


16-2485
phenyl
H
H
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


16-2505
3-cyanophenyl
H
H
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


16-2506
4-cyanophenyl
H
H
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


16-2521
2-chloropyridin-3-yl
H
H
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


16-2563
phenyl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


16-2583
3-cyanophenyl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


16-2584
4-cyanophenyl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


16-2599
2-chloropyridin-3-yl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


16-2641
phenyl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


16-2661
3-cyanophenyl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


16-2662
4-cyanophenyl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


16-2677
2-chloropyridin-3-yl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


16-2719
phenyl
H
H
N-oxide
H
H
H
F
H
heptafluoroisopropyl
H
CF3


16-2720
phenyl
H
H
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


16-2721
2-fluorophenyl
H
H
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


16-2732
4-iodophenyl
H
H
N-oxide
H
H
H
Cl
H
pentafluoroethyl
H
CF3


16-2739
2-cyanophenyl
H
H
N-oxide
H
H
H
Cl
H
pentafluoroethyl
H
C2F5


16-2740
3-cyanophenyl
H
H
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


16-2741
4-cyanophenyl
H
H
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


16-2744
2,4-dichlorophenyl
H
H
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
C2F5


16-2745
2-chloro-4-fluorophenyl
H
H
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


16-2748
2-bromo-4-chlorophenyl
H
H
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


16-2756
2-chloropyridin-3-yl
H
H
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


16-2769
5-fluoropyridin-3-yl
H
H
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
C2F5


16-2771
5-bromopyridin-3-yl
H
H
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


16-2772
5-iodopyridin-3-yl
H
H
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
i-C3F7


16-2774
5-nitropyridin-3-yl
H
H
N-oxide
H
H
H
Cl
H
pentafluoroethyl
H
CF3


16-2776
4-fluoropyridin-3-yl
H
H
N-oxide
H
H
H
Cl
H
pentafluoroethyl
H
CF3


16-2778
4-bromopyridin-3-yl
H
H
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


16-2779
4-iodopyridin-3-yl
H
H
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
i-C3F7


16-2796
6-chloropyridin-2-yl
H
H
N-oxide
H
H
H
Cl
H
pentafluoroethyl
H
CF3


16-2798
phenyl
H
H
N-oxide
H
H
H
F
H
nonafluoro-2-butyl
H
CF3


16-2799
phenyl
H
H
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


16-2811
4-iodophenyl
H
H
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


16-2812
(2-trifluoromethyl)phenyl
H
H
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


16-2819
3-cyanophenyl
H
H
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


16-2820
4-cyanophenyl
H
H
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


16-2829
2-chloro-4-nitrophenyl
H
H
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


16-2835
2-chloropyridin-3-yl
H
H
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


16-2848
5-fluoropyridin-3-yl
H
H
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


16-2850
5-bromopyridin-3-yl
H
H
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
n-C3F7


16-2851
5-iodopyridin-3-yl
H
H
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


16-2855
4-fluoropyridin-3-yl
H
H
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


16-2859
4-(trifluoromethyl)pyridin-3-yl
H
H
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
n-C3F7


16-2860
4-nitropyridin-3-yl
H
H
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


16-2877
phenyl
H
H
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-2878
2-fluorophenyl
H
H
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-2897
3-cyanophenyl
H
H
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-2898
4-cyanophenyl
H
H
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-2913
2-chloropyridin-3-yl
H
H
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-2920
6-chloropyridin-3-yl
H
H
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-2942
pyridin-4-yl
H
H
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


16-2955
phenyl
H
H
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-2963
3-bromophenyl
H
H
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-2969
(3-trifluoromethyl)phenyl
H
H
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-2975
3-cyanophenyl
H
H
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-2976
4-cyanophenyl
H
H
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-2991
2-chloropyridin-3-yl
H
H
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-2998
6-chloropyridin-3-yl
H
H
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-3005
5-chloropyridin-3-yl
H
H
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-3020
pyridin-4-yl
H
H
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


16-3033
phenyl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3034
2-fluorophenyl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3035
3-fluorophenyl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3036
4-fluorophenyl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3037
2-chlorophenyl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3038
3-chlorophenyl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3039
4-chlorophenyl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3040
2-bromophenyl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3041
3-bromophenyl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3042
4-bromophenyl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3043
2-iodophenyl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3044
3-iodophenyl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3045
4-iodophenyl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3046
(2-trifluoromethyl)phenyl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3047
(3-trifluoromethyl)phenyl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3048
(4-trifluoromethyl)phenyl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3049
2-nitrophenyl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3050
3-nitrophenyl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3051
4-nitrophenyl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3052
2-cyanophenyl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3053
3-cyanophenyl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3054
4-cyanophenyl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3055
2,6-difluorophenyl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3056
3,4-dichlorophenyl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3057
2,4-dichlorophenyl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3058
2-chloro-4-fluorophenyl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3059
2-chloro-4,5-difluorophenyl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3060
4-bromo-2-chlorophenyl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3061
2-bromo-4-chlorophenyl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3062
2-bromo-4-fluorophenyl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3063
2-chloro-4-nitrophenyl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3064
3,5-dicyanophenyl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3065
4-cyano-2-fluorophenyl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3066
2-chloro-4-cyanophenyl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3067
pyridin-3-yl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3068
2-fluoropyridin-3-yl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3069
2-chloropyridin-3-yl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3070
2-bromopyridin-3-yl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3071
2-iodopyridin-3-yl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3072
2-(trifluoromethyl)pyridin-3-yl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3073
2-nitropyridin-3-yl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3074
2-cyanopyridin-3-yl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3075
6-fluoropyridin-3-yl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3076
6-chloropyridin-3-yl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3077
6-bromopyridin-3-yl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3078
6-iodopyridin-3-yl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3079
6-(trifluoromethyl)pyridin-3-yl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3080
6-nitropyridin-3-yl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3081
6-cyanopyridin-3-yl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3082
5-fluoropyridin-3-yl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3083
5-chloropyridin-3-yl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3084
5-bromopyridin-3-yl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3085
5-iodopyridin-3-yl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3086
5-(trifluoromethyl)pyridin-3-yl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3087
5-nitropyridin-3-yl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3088
5-cyanopyridin-3-yl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3089
4-fluoropyridin-3-yl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3090
4-chloropyridin-3-yl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3091
4-bromopyridin-3-yl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3092
4-iodopyridin-3-yl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3093
4-(trifluoromethyl)pyridin-3-yl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3094
4-nitropyridin-3-yl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3095
4-cyanopyridin-3-yl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3096
2,6-dichloropyridin-3-yl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3097
pyridin-3-yl N-oxide
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3098
pyridin-4-yl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3099
2-chloropyridin-4-yl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3100
3-bromopyridin-4-yl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3101
3,5-dichloropyridin-4-yl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3102
3-(trifluoromethyl)pyridin-4-yl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3103
2,6-dicyanopyridin-4-yl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3104
pyridin-4-yl N-oxide
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3105
pyridin-2-yl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3106
3-chloropyridin-2-yl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3107
4-bromopyridin-2-yl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3108
5-iodopyridin-2-yl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3109
6-chloropyridin-2-yl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3110
4-cyanopyridin-2-yl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


16-3111
phenyl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3112
2-fluorophenyl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3113
3-fluorophenyl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3114
4-fluorophenyl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3115
2-chlorophenyl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3116
3-chlorophenyl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3117
4-chlorophenyl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3118
2-bromophenyl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3119
3-bromophenyl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3120
4-bromophenyl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3121
2-iodophenyl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3122
3-iodophenyl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3123
4-iodophenyl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3124
(2-trifluoromethyl)phenyl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3125
(3-trifluoromethyl)phenyl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3126
(4-trifluoromethyl)phenyl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3127
2-nitrophenyl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3128
3-nitrophenyl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3129
4-nitrophenyl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3130
2-cyanophenyl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3131
3-cyanophenyl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3132
4-cyanophenyl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3133
2,6-difluorophenyl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3134
3,4-dichlorophenyl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3135
2,4-dichlorophenyl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3136
2-chloro-4-fluorophenyl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3137
2-chloro-4,5-difluorophenyl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3138
4-bromo-2-chlorophenyl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3139
2-bromo-4-chlorophenyl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3140
2-bromo-4-fluorophenyl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3141
2-chloro-4-nitrophenyl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3142
3,5-dicyanophenyl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3143
4-cyano-2-fluorophenyl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3144
2-chloro-4-cyanophenyl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3145
pyridin-3-yl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3146
2-fluoropyridin-3-yl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3147
2-chloropyridin-3-yl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3148
2-bromopyridin-3-yl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3149
2-iodopyridin-3-yl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3150
2-(trifluoromethyl)pyridin-3-yl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3151
2-nitropyridin-3-yl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3152
2-cyanopyridin-3-yl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3153
6-fluoropyridin-3-yl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3154
6-chloropyridin-3-yl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3155
6-bromopyridin-3-yl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3156
6-iodopyridin-3-yl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3157
6-(trifluoromethyl)pyridin-3-yl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3158
6-nitropyridin-3-yl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3159
6-cyanopyridin-3-yl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3160
5-fluoropyridin-3-yl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3161
5-chloropyridin-3-yl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3162
5-bromopyridin-3-yl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3163
5-iodopyridin-3-yl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3164
5-(trifluoromethyl)pyridin-3-yl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3165
5-nitropyridin-3-yl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3166
5-cyanopyridin-3-yl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3167
4-fluoropyridin-3-yl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3168
4-chloropyridin-3-yl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3169
4-bromopyridin-3-yl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3170
4-iodopyridin-3-yl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3171
4-(trifluoromethyl)pyridin-3-yl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3172
4-nitropyridin-3-yl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3173
4-cyanopyridin-3-yl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3174
2,6-dichloropyridin-3-yl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3175
pyridin-3-yl N-oxide
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3176
pyridin-4-yl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3177
2-chloropyridin-4-yl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3178
3-bromopyridin-4-yl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3179
3,5-dichloropyridin-4-yl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3180
3-(trifluoromethyl)pyridin-4-yl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3181
2,6-dicyanopyridin-4-yl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3182
pyridin-4-yl N-oxide
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3183
pyridin-2-yl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3184
3-chloropyridin-2-yl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3185
4-bromopyridin-2-yl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3186
5-iodopyridin-2-yl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3187
6-chloropyridin-2-yl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3188
4-cyanopyridin-2-yl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


16-3189
phenyl
H
H
N-oxide
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


16-3196
2-bromophenyl
H
H
N-oxide
H
H
H
OCF3
H
heptafluoroisopropyl
H
OC2F5


16-3201
4-iodophenyl
H
H
N-oxide
H
H
H
OCF3
H
pentafluoroethyl
H
OCF3


16-3204
3-cyanophenyl
H
H
N-oxide
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


16-3205
4-cyanophenyl
H
H
N-oxide
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


16-3213
2-bromo-4-fluorophenyl
H
H
N-oxide
H
H
H
OC2F5
H
heptafluoroisopropyl
H
OCF3


16-3220
2-chloropyridin-3-yl
H
H
N-oxide
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


16-3229
5-cyanopyridin-3-yl
H
H
N-oxide
H
H
H
OC2F5
H
heptafluoroisopropyl
H
OC2F5


16-3231
4-cyanopyridin-3-yl
H
H
N-oxide
H
H
H
OCF3
H
heptafluoroisopropyl
H
OC2F5


16-3245
phenyl
H
H
N-oxide
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


16-3252
2-bromophenyl
H
H
N-oxide
H
H
H
OC2F5
H
nonafluoro-2-butyl
H
OCF3


16-3258
(2-trifluoromethyl)phenyl
H
H
N-oxide
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OC2F5


16-3260
3-cyanophenyl
H
H
N-oxide
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


16-3261
4-cyanophenyl
H
H
N-oxide
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


16-3276
2-chloropyridin-3-yl
H
H
N-oxide
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


16-3283
6-cyanopyridin-3-yl
H
H
N-oxide
H
H
H
OC2F5
H
nonafluoro-2-butyl
H
OCF3


16-3284
5-chloropyridin-3-yl
H
H
N-oxide
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OC2F5


16-3301
phenyl
H
H
N-oxide
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


16-3308
2-bromophenyl
H
H
N-oxide
H
H
H
CF3
H
heptafluoroisopropyl
H
OC2F5


16-3313
4-iodophenyl
H
H
N-oxide
H
H
H
CF3
H
pentafluoroethyl
H
OCF3


16-3314
(2-trifluoromethyl)phenyl
H
H
N-oxide
H
H
H
C2F5
H
heptafluoroisopropyl
H
OC2F5


16-3315
3-nitrophenyl
H
H
N-oxide
H
H
H
C2F5
H
heptafluoroisopropyl
H
OCF3


16-3316
3-cyanophenyl
H
H
N-oxide
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


16-3317
4-cyanophenyl
H
H
N-oxide
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


16-3324
2-bromo-4-chlorophenyl
H
H
N-oxide
H
H
H
n-C3F7
H
heptafluoroisopropyl
H
OCF3


16-3328
4-cyano-2-fluorophenyl
H
H
N-oxide
H
H
H
i-C3F7
H
heptafluoroisopropyl
H
OCF3


16-3332
2-chloropyridin-3-yl
H
H
N-oxide
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


16-3338
6-chloropyridin-3-yl
H
H
N-oxide
H
H
H
n-C3F7
H
heptafluoroisopropyl
H
OC2F5


16-3341
5-cyanopyridin-3-yl
H
H
N-oxide
H
H
H
i-C3F7
H
heptafluoroisopropyl
H
OC2F5


16-3357
phenyl
H
H
N-oxide
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


16-3368
3-iodophenyl
H
H
N-oxide
H
H
H
CF3
H
nonafluoro-2-butyl
H
OC2F5


16-3371
3-nitrophenyl
H
H
N-oxide
H
H
H
C2F5
H
nonafluoro-2-butyl
H
OCF3


16-3372
3-cyanophenyl
H
H
N-oxide
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


16-3373
4-cyanophenyl
H
H
N-oxide
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


16-3379
4-bromo-2-chlorophenyl
H
H
N-oxide
H
H
H
i-C3F7
H
nonafluoro-2-butyl
H
OCF3


16-3382
2-chloro-4-nitrophenyl
H
H
N-oxide
H
H
H
n-C3F7
H
nonafluoro-2-butyl
H
OCF3


16-3388
2-chloropyridin-3-yl
H
H
N-oxide
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


16-3397
5-cyanopyridin-3-yl
H
H
N-oxide
H
H
H
C2F5
H
nonafluoro-2-butyl
H
OC2F5


16-3399
4-cyanopyridin-3-yl
H
H
N-oxide
H
H
H
n-C3F7
H
nonafluoro-2-butyl
H
OC2F5


16-3410
5-iodopyridin-2-yl
H
H
N-oxide
H
H
H
i-C3F7
H
nonafluoro-2-butyl
H
OC2F5


16-3413
phenyl
H
H
N-oxide
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


16-3425
4-iodophenyl
H
H
N-oxide
H
H
H
CF3
H
pentafluoroethyl
H
CF3


16-3427
(3-trifluoromethyl)phenyl
H
H
N-oxide
H
H
H
C2F5
H
heptafluoroisopropyl
H
CF3


16-3433
3-cyanophenyl
H
H
N-oxide
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


16-3434
4-cyanophenyl
H
H
N-oxide
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


16-3440
4-bromo-2-chlorophenyl
H
H
N-oxide
H
H
H
n-C3F7
H
heptafluoroisopropyl
H
CF3


16-3445
4-cyano-2-fluorophenyl
H
H
N-oxide
H
H
H
i-C3F7
H
heptafluoroisopropyl
H
CF3


16-3447
pyridin-3-yl
H
H
N-oxide
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


16-3449
2-chloropyridin-3-yl
H
H
N-oxide
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


16-3450
2-bromopyridin-3-yl
H
H
N-oxide
H
H
H
C2F5
H
heptafluoroisopropyl
H
C2F5


16-3461
6-cyanopyridin-3-yl
H
H
N-oxide
H
H
H
C2F5
H
heptafluoroisopropyl
H
n-C3F7


16-3465
4-cyanopyridin-3-yl
H
H
N-oxide
H
H
H
C2F5
H
heptafluoroisopropyl
H
i-C3F7


16-3481
phenyl
H
H
N-oxide
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


16-3493
4-iodophenyl
H
H
N-oxide
H
H
H
C2F5
H
nonafluoro-2-butyl
H
CF3


16-3501
3-cyanophenyl
H
H
N-oxide
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


16-3502
4-cyanophenyl
H
H
N-oxide
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


16-3508
4-bromo-2-chlorophenyl
H
H
N-oxide
H
H
H
n-C3F7
H
nonafluoro-2-butyl
H
CF3


16-3513
4-cyano-2-fluorophenyl
H
H
N-oxide
H
H
H
i-C3F7
H
nonafluoro-2-butyl
H
CF3


16-3517
2-chloropyridin-3-yl
H
H
N-oxide
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


16-3518
2-bromopyridin-3-yl
H
H
N-oxide
H
H
H
C2F5
H
nonafluoro-2-butyl
H
C2F5


16-3529
6-cyanopyridin-3-yl
H
H
N-oxide
H
H
H
C2F5
H
nonafluoro-2-butyl
H
n-C3F7


16-3536
pyridin-4-yl
H
H
N-oxide
H
H
H
C2F5
H
nonafluoro-2-butyl
H
i-C3F7











embedded image





















TABLE 17





com-














pound


number
Q1
R1
R2
A
X2
X3
X4
Y1
Y2
Y3
Y4
Y5







17-1
phenyl
Me
H
N
H
H
H
F
H
heptafluoroisopropyl
H
F


17-2
3-cyanophenyl
Me
H
N
H
H
H
F
H
heptafluoroisopropyl
H
F


17-3
4-cyanophenyl
Me
H
N
H
H
H
F
H
heptafluoroisopropyl
H
F


17-4
2-chloropyridin-3-yl
Me
H
N
H
H
H
F
H
heptafluoroisopropyl
H
F


17-5
phenyl
Me
H
N
H
H
H
F
H
nonafluoro-2-butyl
H
F


17-6
3-cyanophenyl
Me
H
N
H
H
H
F
H
nonafluoro-2-butyl
H
F


17-7
4-cyanophenyl
Me
H
N
H
H
H
F
H
nonafluoro-2-butyl
H
F


17-8
2-chloropyridin-3-yl
Me
H
N
H
H
H
F
H
nonafluoro-2-butyl
H
F


17-9
phenyl
Me
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


17-29
3-cyanophenyl
Me
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


17-30
4-cyanophenyl
Me
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


17-45
2-chloropyridin-3-yl
Me
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


17-87
phenyl
Me
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


17-107
3-cyanophenyl
Me
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


17-108
4-cyanophenyl
Me
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


17-123
2-chloropyridin-3-yl
Me
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


17-165
phenyl
Me
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
Br


17-185
3-cyanophenyl
Me
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
Br


17-186
4-cyanophenyl
Me
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
Br


17-201
2-chloropyridin-3-yl
Me
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
Br


17-243
phenyl
Me
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


17-263
3-cyanophenyl
Me
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


17-264
4-cyanophenyl
Me
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


17-279
2-chloropyridin-3-yl
Me
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


17-321
phenyl
Me
H
N
H
H
H
I
H
heptafluoroisopropyl
H
I


17-341
3-cyanophenyl
Me
H
N
H
H
H
I
H
heptafluoroisopropyl
H
I


17-342
4-cyanophenyl
Me
H
N
H
H
H
I
H
heptafluoroisopropyl
H
I


17-357
2-chloropyridin-3-yl
Me
H
N
H
H
H
I
H
heptafluoroisopropyl
H
I


17-399
phenyl
Me
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
I


17-400
2-fluorophenyl
Me
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
I


17-419
3-cyanophenyl
Me
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
I


17-420
4-cyanophenyl
Me
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
I


17-435
2-chloropyridin-3-yl
Me
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
I


17-477
phenyl
Me
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


17-497
3-cyanophenyl
Me
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


17-498
4-cyanophenyl
Me
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


17-513
2-chloropyridin-3-yl
Me
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


17-555
phenyl
Me
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


17-575
3-cyanophenyl
Me
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


17-576
4-cyanophenyl
Me
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


17-591
2-chloropyridin-3-yl
Me
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


17-633
phenyl
Me
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


17-653
3-cyanophenyl
Me
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


17-654
4-cyanophenyl
Me
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


17-669
2-chloropyridin-3-yl
Me
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


17-711
phenyl
Me
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


17-731
3-cyanophenyl
Me
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


17-732
4-cyanophenyl
Me
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


17-747
2-chloropyridin-3-yl
Me
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


17-789
phenyl
Me
H
N
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


17-809
3-cyanophenyl
Me
H
N
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


17-810
4-cyanophenyl
Me
H
N
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


17-825
2-chloropyridin-3-yl
Me
H
N
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


17-867
phenyl
Me
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


17-887
3-cyanophenyl
Me
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


17-888
4-cyanophenyl
Me
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


17-903
2-chloropyridin-3-yl
Me
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


17-945
phenyl
Me
H
N
H
H
H
F
H
heptafluoroisopropyl
H
CF3


17-946
phenyl
Me
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


17-957
3-iodophenyl
Me
H
N
H
H
H
Cl
H
pentafluoroethyl
H
CF3


17-958
4-iodophenyl
Me
H
N
H
H
H
Cl
H
pentafluoroethyl
H
CF3


17-965
2-cyanophenyl
Me
H
N
H
H
H
Cl
H
pentafluoroethyl
H
C2F5


17-966
3-cyanophenyl
Me
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


17-967
4-cyanophenyl
Me
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


17-970
2,4-dichlorophenyl
Me
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
C2F5


17-971
2-chloro-4-fluorophenyl
n-Pr
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


17-974
2-bromo-4-chlorophenyl
Me
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


17-981
2-fluoropyridin-3-yl
Me
H
N
H
H
H
Cl
H
pentafluoroethyl
H
CF3


17-982
2-chloropyridin-3-yl
Me
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


17-988
6-fluoropyridin-3-yl
i-Pr
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


17-995
5-fluoropyridin-3-yl
Me
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
C2F5


17-997
5-bromopyridin-3-yl
Me
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


17-998
5-iodopyridin-3-yl
Me
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
i-C3F7


17-1000
5-nitropyridin-3-yl
Me
H
N
H
H
H
Cl
H
pentafluoroethyl
H
CF3


17-1002
4-fluoropyridin-3-yl
Me
H
N
H
H
H
Cl
H
pentafluoroethyl
H
CF3


17-1004
4-bromopyridin-3-yl
CH2CH═CH2
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


17-1005
4-iodopyridin-3-yl
Me
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
i-C3F7


17-1011
pyridin-4-yl
CN
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


17-1023
4-cyanopyridin-2-yl
Me
H
N
H
H
H
Cl
H
pentafluoroethyl
H
CF3


17-1024
phenyl
Me
H
N
H
H
H
F
H
nonafluoro-2-butyl
H
CF3


17-1025
phenyl
Me
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


17-1033
3-bromophenyl
CH2C≡CH
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


17-1038
(2-trifluoromethyl)phenyl
Me
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


17-1040
(4-trifluoromethyl)phenyl
NH2
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


17-1045
3-cyanophenyl
Me
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


17-1046
4-cyanophenyl
Me
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


17-1053
2-bromo-4-chlorophenyl
C(O)OMe
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


17-1055
2-chloro-4-nitrophenyl
Me
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


17-1061
2-chloropyridin-3-yl
Me
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


17-1074
5-fluoropyridin-3-yl
C(O)OEt
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


17-1076
5-bromopyridin-3-yl
Me
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
n-C3F7


17-1077
5-iodopyridin-3-yl
Me
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


17-1081
4-fluoropyridin-3-yl
Me
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


17-1083
4-bromopyridin-3-yl
C(O)C(O)Me
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


17-1085
4-(trifluoromethyl )pyridin-3-yl
Me
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
n-C3F7


17-1086
4-nitropyridin-3-yl
C(O)C(O)Et
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


17-1100
5-iodopyridin-2-yl
C(O)Me
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


17-1102
4-cyanopyridin-2-yl
C(O)Et
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


17-1103
phenyl
Me
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


17-1104
2-fluorophenyl
Me
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


17-1117
(3-trifluoromethyl)phenyl
S(O)2Me
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


17-1135
4-cyano-2-fluorophenyl
S(O)2Et
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


17-1139
2-chloropyridin-3-yl
Me
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


17-1150
6-nitropyridin-3-yl
CH2Ph
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


17-1159
4-fluoropyridin-3-yl
CH2(3-Py)
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


17-1180
4-cyanopyridin-2-yl
CH2(3-Py—N-
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3




oxide)


17-1181
phenyl
Me
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


17-1182
2-fluorophenyl
Me
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


17-1201
3-cyanophenyl
Me
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


17-1202
4-cyanophenyl
Me
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


17-1208
4-bromo-2-chlorophenyl
Et
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


17-1217
2-chloropyridin-3-yl
Me
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


17-1234
5-(trifluoromethyl)pyridin-3-yl
CN
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


17-1259
phenyl
Me
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


17-1260
2-fluorophenyl
Me
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


17-1279
3-cyanophenyl
Me
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


17-1280
4-cyanophenyl
Me
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


17-1295
2-chloropyridin-3-yl
Me
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


17-1308
5-fluoropyridin-3-yl
C(O)Me
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


17-1337
phenyl
Me
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


17-1338
2-fluorophenyl
Me
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


17-1357
3-cyanophenyl
Me
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


17-1358
4-cyanophenyl
Me
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


17-1373
2-chloropyridin-3-yl
Me
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


17-1415
phenyl
Me
H
N
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


17-1446
2-chloropyridin-3-yl
Me
H
N
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


17-1471
phenyl
Me
H
N
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


17-1502
2-chloropyridin-3-yl
Me
H
N
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


17-1527
phenyl
Me
H
N
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


17-1558
2-chloropyridin-3-yl
Me
H
N
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


17-1583
phenyl
Me
H
N
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


17-1614
2-chloropyridin-3-yl
Me
H
N
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


17-1639
phenyl
Me
H
N
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


17-1659
3-cyanophenyl
Me
H
N
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


17-1660
4-cyanophenyl
Me
H
N
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


17-1675
2-chloropyridin-3-yl
Me
H
N
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


17-1707
phenyl
Me
H
N
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


17-1727
3-cyanophenyl
Me
H
N
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


17-1728
4-cyanophenyl
Me
H
N
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


17-1743
2-chloropyridin-3-yl
Me
H
N
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


17-1775
phenyl
Me
H
N-oxide
H
H
H
F
H
heptafluoroisopropyl
H
F


17-1776
3-cyanophenyl
Me
H
N-oxide
H
H
H
F
H
heptafluoroisopropyl
H
F


17-1777
4-cyanophenyl
Me
H
N-oxide
H
H
H
F
H
heptafluoroisopropyl
H
F


17-1778
2-chloropyridin-3-yl
Me
H
N-oxide
H
H
H
F
H
heptafluoroisopropyl
H
F


17-1779
phenyl
Me
H
N-oxide
H
H
H
F
H
nonafluoro-2-butyl
H
F


17-1780
3-cyanophenyl
Me
H
N-oxide
H
H
H
F
H
nonafluoro-2-butyl
H
F


17-1781
4-cyanophenyl
Me
H
N-oxide
H
H
H
F
H
nonafluoro-2-butyl
H
F


17-1782
2-chloropyridin-3-yl
Me
H
N-oxide
H
H
H
F
H
nonafluoro-2-butyl
H
F


17-1783
phenyl
Me
H
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


17-1803
3-cyanophenyl
Me
H
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


17-1804
4-cyanophenyl
Me
H
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


17-1819
2-chloropyridin-3-yl
Me
H
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


17-1861
phenyl
Me
H
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


17-1881
3-cyanophenyl
Me
H
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


17-1882
4-cyanophenyl
Me
H
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


17-1897
2-chloropyridin-3-yl
Me
H
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


17-1939
phenyl
Me
H
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
Br


17-1959
3-cyanophenyl
Me
H
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
Br


17-1960
4-cyanophenyl
Me
H
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
Br


17-1975
2-chloropyridin-3-yl
Me
H
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
Br


17-2017
phenyl
Me
H
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


17-2037
3-cyanophenyl
Me
H
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


17-2038
4-cyanophenyl
Me
H
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


17-2053
2-chloropyridin-3-yl
Me
H
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


17-2095
phenyl
Me
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
I


17-2114
2-cyanophenyl
Me
H
N-oxide
H
H
H
I
H
pentafluoroethyl
H
I


17-2115
3-cyanophenyl
Me
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
I


17-2131
2-chloropyridin-3-yl
Me
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
I


17-2173
phenyl
Me
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
I


17-2193
3-cyanophenyl
Me
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
I


17-2194
4-cyanophenyl
Me
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
I


17-2209
2-chloropyridin-3-yl
Me
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
I


17-2251
phenyl
Me
H
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


17-2271
3-cyanophenyl
Me
H
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


17-2272
4-cyanophenyl
Me
H
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


17-2287
2-chloropyridin-3-yl
Me
H
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


17-2329
phenyl
Me
H
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


17-2349
3-cyanophenyl
Me
H
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


17-2350
4-cyanophenyl
Me
H
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


17-2365
2-chloropyridin-3-yl
Me
H
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


17-2407
phenyl
Me
H
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


17-2427
3-cyanophenyl
Me
H
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


17-2428
4-cyanophenyl
Me
H
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


17-2443
2-chloropyridin-3-yl
Me
H
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


17-2485
phenyl
Me
H
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


17-2505
3-cyanophenyl
Me
H
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


17-2506
4-cyanophenyl
Me
H
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


17-2563
phenyl
Me
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


17-2583
3-cyanophenyl
Me
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


17-2584
4-cyanophenyl
Me
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


17-2599
2-chloropyridin-3-yl
Me
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


17-2641
phenyl
Me
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


17-2661
3-cyanophenyl
Me
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


17-2662
4-cyanophenyl
Me
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


17-2677
2-chloropyridin-3-yl
Me
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


17-2719
phenyl
Me
H
N-oxide
H
H
H
F
H
heptafluoroisopropyl
H
CF3


17-2720
phenyl
Me
H
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


17-2740
3-cyanophenyl
Me
H
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


17-2741
4-cyanophenyl
Me
H
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


17-2756
2-chloropyridin-3-yl
Me
H
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


17-2798
phenyl
Me
H
N-oxide
H
H
H
F
H
nonafluoro-2-butyl
H
CF3


17-2799
phenyl
Me
H
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


17-2819
3-cyanophenyl
Me
H
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


17-2820
4-cyanophenyl
Me
H
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


17-2835
2-chloropyridin-3-yl
Me
H
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


17-2877
phenyl
Me
H
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


17-2897
3-cyanophenyl
Me
H
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


17-2898
4-cyanophenyl
Me
H
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


17-2913
2-chloropyridin-3-yl
Me
H
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


17-2914
2-bromopyridin-3-yl
Me
H
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


17-2955
phenyl
Me
H
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


17-2975
3-cyanophenyl
Me
H
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


17-2976
4-cyanophenyl
Me
H
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


17-2991
2-chloropyridin-3-yl
Me
H
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


17-3033
phenyl
Me
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


17-3053
3-cyanophenyl
Me
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


17-3054
4-cyanophenyl
Me
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


17-3069
2-chloropyridin-3-yl
Me
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


17-3111
phenyl
Me
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


17-3131
3-cyanophenyl
Me
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


17-3132
4-cyanophenyl
Me
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


17-3147
2-chloropyridin-3-yl
Me
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


17-3189
phenyl
Me
H
N-oxide
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


17-3220
2-chloropyridin-3-yl
Me
H
N-oxide
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


17-3245
phenyl
Me
H
N-oxide
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


17-3276
2-chloropyridin-3-yl
Me
H
N-oxide
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


17-3301
phenyl
Me
H
N-oxide
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


17-3332
2-chloropyridin-3-yl
Me
H
N-oxide
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


17-3357
phenyl
Me
H
N-oxide
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


17-3388
2-chloropyridin-3-yl
Me
H
N-oxide
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


17-3413
phenyl
Me
H
N-oxide
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


17-3433
3-cyanophenyl
Me
H
N-oxide
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


17-3434
4-cyanophenyl
Me
H
N-oxide
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


17-3449
2-chloropyridin-3-yl
Me
H
N-oxide
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


17-3481
phenyl
Me
H
N-oxide
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


17-3501
3-cyanophenyl
Me
H
N-oxide
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


17-3502
4-cyanophenyl
Me
H
N-oxide
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


17-3517
2-chloropyridin-3-yl
Me
H
N-oxide
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3











embedded image





















TABLE 18





compound














number
Q1
R1
R2
A
X2
X3
X4
Y1
Y2
Y3
Y4
Y5







18-1
phenyl
H
Me
N
H
H
H
F
H
heptafluoroisopropyl
H
F


18-2
3-cyanophenyl
H
Me
N
H
H
H
F
H
heptafluoroisopropyl
H
F


18-3
4-cyanophenyl
H
Me
N
H
H
H
F
H
heptafluoroisopropyl
H
F


18-4
2-chloropyridin-3-yl
H
Me
N
H
H
H
F
H
heptafluoroisopropyl
H
F


18-5
phenyl
H
Me
N
H
H
H
F
H
nonafluoro-2-butyl
H
F


18-6
3-cyanophenyl
H
Me
N
H
H
H
F
H
nonafluoro-2-butyl
H
F


18-7
4-cyanophenyl
H
Me
N
H
H
H
F
H
nonafluoro-2-butyl
H
F


18-8
2-chloropyridin-3-yl
H
Me
N
H
H
H
F
H
nonafluoro-2-butyl
H
F


18-9
phenyl
H
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


18-29
3-cyanophenyl
H
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


18-30
4-cyanophenyl
H
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


18-45
2-chloropyridin-3-yl
H
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


18-87
phenyl
H
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


18-107
3-cyanophenyl
H
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


18-108
4-cyanophenyl
H
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


18-123
2-chloropyridin-3-yl
H
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


18-165
phenyl
H
Me
N
H
H
H
Br
H
heptafluoroisopropyl
H
Br


18-176
3-iodophenyl
H
Me
N
H
H
H
Br
H
pentafluoroethyl
H
Br


18-177
4-iodophenyl
H
Me
N
H
H
H
Br
H
pentafluoroethyl
H
Br


18-185
3-cyanophenyl
H
Me
N
H
H
H
Br
H
heptafluoroisopropyl
H
Br


18-186
4-cyanophenyl
H
Me
N
H
H
H
Br
H
heptafluoroisopropyl
H
Br


18-201
2-chloropyridin-3-yl
H
Me
N
H
H
H
Br
H
heptafluoroisopropyl
H
Br


18-243
phenyl
H
Me
N
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


18-263
3-cyanophenyl
H
Me
N
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


18-264
4-cyanophenyl
H
Me
N
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


18-279
2-chloropyridin-3-yl
H
Me
N
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


18-321
phenyl
H
Me
N
H
H
H
I
H
heptafluoroisopropyl
H
I


18-341
3-cyanophenyl
H
Me
N
H
H
H
I
H
heptafluoroisopropyl
H
I


18-342
4-cyanophenyl
H
Me
N
H
H
H
I
H
heptafluoroisopropyl
H
I


18-357
2-chloropyridin-3-yl
H
Me
N
H
H
H
I
H
heptafluoroisopropyl
H
I


18-399
phenyl
H
Me
N
H
H
H
I
H
nonafluoro-2-butyl
H
I


18-419
3-cyanophenyl
H
Me
N
H
H
H
I
H
nonafluoro-2-butyl
H
I


18-420
4-cyanophenyl
H
Me
N
H
H
H
I
H
nonafluoro-2-butyl
H
I


18-435
2-chloropyridin-3-yl
H
Me
N
H
H
H
I
H
nonafluoro-2-butyl
H
I


18-477
phenyl
H
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


18-497
3-cyanophenyl
H
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


18-498
4-cyanophenyl
H
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


18-513
2-chloropyridin-3-yl
H
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


18-555
phenyl
H
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


18-575
3-cyanophenyl
H
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


18-576
4-cyanophenyl
H
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


18-591
2-chloropyridin-3-yl
H
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


18-633
phenyl
H
Me
N
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


18-653
3-cyanophenyl
H
Me
N
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


18-654
4-cyanophenyl
H
Me
N
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


18-669
2-chloropyridin-3-yl
H
Me
N
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


18-711
phenyl
H
Me
N
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


18-731
3-cyanophenyl
H
Me
N
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


18-732
4-cyanophenyl
H
Me
N
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


18-747
2-chloropyridin-3-yl
H
Me
N
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


18-789
phenyl
H
Me
N
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


18-809
3-cyanophenyl
H
Me
N
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


18-810
4-cyanophenyl
H
Me
N
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


18-825
2-chloropyridin-3-yl
H
Me
N
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


18-867
phenyl
H
Me
N
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


18-887
3-cyanophenyl
H
Me
N
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


18-888
4-cyanophenyl
H
Me
N
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


18-903
2-chloropyridin-3-yl
H
Me
N
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


18-945
phenyl
H
Me
N
H
H
H
F
H
heptafluoroisopropyl
H
CF3


18-946
phenyl
H
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


18-957
3-iodophenyl
H
Me
N
H
H
H
Cl
H
pentafluoroethyl
H
CF3


18-958
4-iodophenyl
H
Me
N
H
H
H
Cl
H
pentafluoroethyl
H
CF3


18-960
(3-trifluoromethyl)phenyl
H
Et
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


18-965
2-cyanophenyl
H
Me
N
H
H
H
Cl
H
pentafluoroethyl
H
C2F5


18-966
3-cyanophenyl
H
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


18-967
4-cyanophenyl
H
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


18-970
2,4-dichlorophenyl
H
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
C2F5


18-971
2-chloro-4-fluorophenyl
H
n-Pr
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


18-974
2-bromo-4-chlorophenyl
H
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


18-981
2-fluoropyridin-3-yl
H
Me
N
H
H
H
Cl
H
pentafluoroethyl
H
CF3


18-982
2-chloropyridin-3-yl
H
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


18-988
6-fluoropyridin-3-yl
H
i-Pr
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


18-995
5-fluoropyridin-3-yl
H
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
C2F5


18-997
5-bromopyridin-3-yl
H
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


18-998
5-iodopyridin-3-yl
H
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
i-C3F7


18-1000
5-nitropyridin-3-yl
H
Me
N
H
H
H
Cl
H
pentafluoroethyl
H
CF3


18-1002
4-fluoropyridin-3-yl
H
Me
N
H
H
H
Cl
H
pentafluoroethyl
H
CF3


18-1004
4-bromopyridin-3-yl
H
CH2CH═CH2
N
H
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


18-1005
4-iodopyridin-3-yl
H
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
i-C3F7


18-1011
pyridin-4-yl
H
CN
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


18-1023
4-cyanopyridin-2-yl
H
Me
N
H
H
H
Cl
H
pentafluoroethyl
H
CF3


18-1024
phenyl
H
Me
N
H
H
H
F
H
nonafluoro-2-butyl
H
CF3


18-1025
phenyl
H
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


18-1033
3-bromophenyl
H
CH2C≡CH
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


18-1038
(2-trifluoromethyl)phenyl
H
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


18-1040
(4-trifluoromethyl)phenyl
H
NH2
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


18-1045
3-cyanophenyl
H
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


18-1046
4-cyanophenyl
H
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


18-1053
2-bromo-4-chlorophenyl
H
C(O)OMe
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


18-1055
2-chloro-4-nitrophenyl
H
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


18-1061
2-chloropyridin-3-yl
H
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


18-1074
5-fluoropyndin-3-yl
H
C(O)OEt
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


18-1076
5-bromopyridin-3-yl
H
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
n-C3F7


18-1077
5-iodopyridin-3-yl
H
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


18-1081
4-fluoropyridin-3-yl
H
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


18-1083
4-bromopyridin-3-yl
H
C(O)C(O)Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


18-1085
4-(trifluoromethyl)pyridin-
H
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
n-C3F7



3-yl


18-1086
4-nitropyridin-3-yl
H
C(O)C(O)Et
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


18-1100
5-iodopyridin-2-yl
H
C(O)Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


18-1102
4-cyanopyridin-2-yl
H
C(O)Et
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


18-1103
phenyl
H
Me
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


18-1104
2-fluorophenyl
H
Me
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


18-1117
(3-trifluoromethyl)phenyl
H
S(O)2Me
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


18-1123
3-cyanophenyl
H
Me
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


18-1124
4-cyanophenyl
H
Me
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


18-1135
4-cyano-2-fluorophenyl
H
S(O)2Et
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


18-1139
2-chloropyridin-3-yl
H
Me
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


18-1150
6-nitropyridin-3-yl
H
CH2Ph
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


18-1159
4-fluoropyridin-3-yl
H
CH2(3-Py)
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


18-1180
4-cyanopyridin-2-yl
H
CH2(3-Py—N-
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3





oxide)


18-1181
phenyl
H
Me
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


18-1182
2-fluorophenyl
H
Me
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


18-1201
3-cyanophenyl
H
Me
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


18-1202
4-cyanophenyl
H
Me
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


18-1208
4-bromo-2-chlorophenyl
H
Et
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


18-1217
2-chloropyridin-3-yl
H
Me
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


18-1234
5-(trifluoromethyl)pyridin-
H
CN
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3



3-yl


18-1259
phenyl
H
Me
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


18-1260
2-fluorophenyl
H
Me
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


18-1279
3-cyanophenyl
H
Me
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


18-1280
4-cyanophenyl
H
Me
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


18-1295
2-chloropyridin-3-yl
H
Me
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


18-1308
5-fluoropyridin-3-yl
H
C(O)Me
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


18-1337
phenyl
H
Me
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


18-1338
2-fluorophenyl
H
Me
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


18-1357
3-cyanophenyl
H
Me
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


18-1358
4-cyanophenyl
H
Me
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


18-1373
2-chloropyridin-3-yl
H
Me
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


18-1415
phenyl
H
Me
N
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


18-1446
2-chloropyridin-3-yl
H
Me
N
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


18-1471
phenyl
H
Me
N
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


18-1502
2-chloropyridin-3-yl
H
Me
N
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


18-1527
phenyl
H
Me
N
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


18-1558
2-chloropyridin-3-yl
H
Me
N
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


18-1583
phenyl
H
Me
N
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


18-1614
2-chloropyridin-3-yl
H
Me
N
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


18-1639
phenyl
H
Me
N
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


18-1659
3-cyanophenyl
H
Me
N
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


18-1660
4-cyanophenyl
H
Me
N
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


18-1675
2-chloropyridin-3-yl
H
Me
N
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


18-1707
phenyl
H
Me
N
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


18-1727
3-cyanophenyl
H
Me
N
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


18-1728
4-cyanophenyl
H
Me
N
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


18-1743
2-chloropyridin-3-yl
H
Me
N
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


18-1775
phenyl
H
Me
N-oxide
H
H
H
F
H
heptafluoroisopropyl
H
F


18-1776
3-cyanophenyl
H
Me
N-oxide
H
H
H
F
H
heptafluoroisopropyl
H
F


18-1777
4-cyanophenyl
H
Me
N-oxide
H
H
H
F
H
heptafluoroisopropyl
H
F


18-1778
2-chloropyridin-3-yl
H
Me
N-oxide
H
H
H
F
H
heptafluoroisopropyl
H
F


18-1779
phenyl
H
Me
N-oxide
H
H
H
F
H
nonafluoro-2-butyl
H
F


18-1780
3-cyanophenyl
H
Me
N-oxide
H
H
H
F
H
nonafluoro-2-butyl
H
F


18-1781
4-cyanophenyl
H
Me
N-oxide
H
H
H
F
H
nonafluoro-2-butyl
H
F


18-1782
2-chloropyridin-3-yl
H
Me
N-oxide
H
H
H
F
H
nonafluoro-2-butyl
H
F


18-1783
phenyl
H
Me
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


18-1803
3-cyanophenyl
H
Me
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


18-1804
4-cyanophenyl
H
Me
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


18-1819
2-chloropyridin-3-yl
H
Me
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


18-1861
phenyl
H
Me
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


18-1881
3-cyanophenyl
H
Me
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


18-1882
4-cyanophenyl
H
Me
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


18-1897
2-chloropyridin-3-yl
H
Me
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


18-1939
phenyl
H
Me
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
Br


18-1959
3-cyanophenyl
H
Me
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
Br


18-1960
4-cyanophenyl
H
Me
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
Br


18-1975
2-chloropyridin-3-yl
H
Me
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
Br


18-2017
phenyl
H
Me
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


18-2037
3-cyanophenyl
H
Me
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


18-2038
4-cyanophenyl
H
Me
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


18-2053
2-chloropyridin-3-yl
H
Me
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


18-2095
phenyl
H
Me
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
I


18-2115
3-cyanophenyl
H
Me
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
I


18-2116
4-cyanophenyl
H
Me
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
I


18-2131
2-chloropyridin-3-yl
H
Me
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
I


18-2173
phenyl
H
Me
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
I


18-2193
3-cyanophenyl
H
Me
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
I


18-2194
4-cyanophenyl
H
Me
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
I


18-2209
2-chloropyridin-3-yl
H
Me
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
I


18-2251
phenyl
H
Me
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


18-2271
3-cyanophenyl
H
Me
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


18-2272
4-cyanophenyl
H
Me
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


18-2287
2-chloropyridin-3-yl
H
Me
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


18-2291
2-nitropyridin-3-yl
H
Me
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
OC2F5


18-2329
phenyl
H
Me
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


18-2349
3-cyanophenyl
H
Me
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


18-2350
4-cyanophenyl
H
Me
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


18-2365
2-chloropyridin-3-yl
H
Me
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


18-2407
phenyl
H
Me
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


18-2427
3-cyanophenyl
H
Me
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


18-2428
4-cyanophenyl
H
Me
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


18-2443
2-chloropyridin-3-yl
H
Me
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


18-2485
phenyl
H
Me
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


18-2505
3-cyanophenyl
H
Me
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


18-2506
4-cyanophenyl
H
Me
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


18-2521
2-chloropyridin-3-yl
H
Me
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


18-2563
phenyl
H
Me
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


18-2583
3-cyanophenyl
H
Me
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


18-2584
4-cyanophenyl
H
Me
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


18-2599
2-chloropyridin-3-yl
H
Me
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


18-2641
phenyl
H
Me
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


18-2661
3-cyanophenyl
H
Me
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


18-2662
4-cyanophenyl
H
Me
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


18-2677
2-chloropyridin-3-yl
H
Me
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


18-2719
phenyl
H
Me
N-oxide
H
H
H
F
H
heptafluoroisopropyl
H
CF3


18-2720
phenyl
H
Me
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


18-2740
3-cyanophenyl
H
Me
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


18-2741
4-cyanophenyl
H
Me
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


18-2756
2-chloropyridin-3-yl
H
Me
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


18-2798
phenyl
H
Me
N-oxide
H
H
H
F
H
nonafluoro-2-butyl
H
CF3


18-2799
phenyl
H
Me
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


18-2819
3-cyanophenyl
H
Me
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


18-2820
4-cyanophenyl
H
Me
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


18-2835
2-chloropyridin-3-yl
H
Me
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


18-2877
phenyl
H
Me
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


18-2897
3-cyanophenyl
H
Me
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


18-2898
4-cyanophenyl
H
Me
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


18-2913
2-chloropyridin-3-yl
H
Me
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


18-2955
phenyl
H
Me
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


18-2975
3-cyanophenyl
H
Me
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


18-2976
4-cyanophenyl
H
Me
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


18-2991
2-chloropyridin-3-yl
H
Me
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


18-3033
phenyl
H
Me
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


18-3053
3-cyanophenyl
H
Me
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


18-3054
4-cyanophenyl
H
Me
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


18-3069
2-chloropyridin-3-yl
H
Me
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


18-3111
phenyl
H
Me
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


18-3131
3-cyanophenyl
H
Me
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


18-3132
4-cyanophenyl
H
Me
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


18-3147
2-chloropyridin-3-yl
H
Me
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


18-3189
phenyl
H
Me
N-oxide
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


18-3220
2-chloropyridin-3-yl
H
Me
N-oxide
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


18-3245
phenyl
H
Me
N-oxide
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


18-3276
2-chloropyridin-3-yl
H
Me
N-oxide
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


18-3301
phenyl
H
Me
N-oxide
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


18-3332
2-chloropyridin-3-yl
H
Me
N-oxide
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


18-3357
phenyl
H
Me
N-oxide
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


18-3388
2-chloropyridin-3-yl
H
Me
N-oxide
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


18-3413
phenyl
H
Me
N-oxide
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


18-3433
3-cyanophenyl
H
Me
N-oxide
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


18-3434
4-cyanophenyl
H
Me
N-oxide
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


18-3449
2-chloropyridin-3-yl
H
Me
N-oxide
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


18-3481
phenyl
H
Me
N-oxide
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


18-3501
3-cyanophenyl
H
Me
N-oxide
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


18-3502
4-cyanophenyl
H
Me
N-oxide
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


18-3517
2-chloropyridin-3-yl
H
Me
N-oxide
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3











embedded image





















TABLE 19





com-














pound


number
Q1
R1
R2
A
X2
X3
X4
Y1
Y2
Y3
Y4
Y5







19-1
phenyl
Me
Me
N
H
H
H
F
H
heptafluoroisopropyl
H
F


19-2
3-cyanophenyl
Me
Me
N
H
H
H
F
H
heptafluoroisopropyl
H
F


19-3
4-cyanophenyl
Me
Me
N
H
H
H
F
H
heptafluoroisopropyl
H
F


19-4
2-chloropyridin-3-yl
Me
Me
N
H
H
H
F
H
heptafluoroisopropyl
H
F


19-5
phenyl
Me
Me
N
H
H
H
F
H
nonafluoro-2-butyl
H
F


19-6
3-cyanophenyl
Me
Me
N
H
H
H
F
H
nonafluoro-2-butyl
H
F


19-7
4-cyanophenyl
Me
Me
N
H
H
H
F
H
nonafluoro-2-butyl
H
F


19-8
2-chloropyridin-3-yl
Me
Me
N
H
H
H
F
H
nonafluoro-2-butyl
H
Cl


19-9
phenyl
Me
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


19-11
3-fluorophenyl
Et
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


19-12
4-fluorophenyl
Me
Et
N
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


19-29
3-cyanophenyl
Me
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


19-30
4-cyanophenyl
Me
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


19-45
2-chloropyridin-3-yl
Me
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


19-87
phenyl
Me
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


19-107
3-cyanophenyl
Me
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


19-108
4-cyanophenyl
Me
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


19-123
2-chloropyridin-3-yl
Me
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


19-165
phenyl
Me
Me
N
H
H
H
Br
H
heptafluoroisopropyl
H
Br


19-185
3-cyanophenyl
Me
Me
N
H
H
H
Br
H
heptafluoroisopropyl
H
Br


19-186
4-cyanophenyl
Me
Me
N
H
H
H
Br
H
heptafluoroisopropyl
H
Br


19-201
2-chloropyridin-3-yl
Me
Me
N
H
H
H
Br
H
heptafluoroisopropyl
H
Br


19-243
phenyl
Me
Me
N
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


19-263
3-cyanophenyl
Me
Me
N
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


19-264
4-cyanophenyl
Me
Me
N
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


19-279
2-chloropyridin-3-yl
Me
Me
N
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


19-321
phenyl
Me
Me
N
H
H
H
I
H
heptafluoroisopropyl
H
I


19-341
3-cyanophenyl
Me
Me
N
H
H
H
I
H
heptafluoroisopropyl
H
I


19-342
4-cyanophenyl
Me
Me
N
H
H
H
I
H
heptafluoroisopropyl
H
I


19-357
2-chloropyridin-3-yl
Me
Me
N
H
H
H
I
H
heptafluoroisopropyl
H
I


19-399
phenyl
Me
Me
N
H
H
H
I
H
nonafluoro-2-butyl
H
I


19-419
3-cyanophenyl
Me
Me
N
H
H
H
I
H
nonafluoro-2-butyl
H
I


19-420
4-cyanophenyl
Me
Me
N
H
H
H
I
H
nonafluoro-2-butyl
H
I


19-435
2-chloropyridin-3-yl
Me
Me
N
H
H
H
I
H
nonafluoro-2-butyl
H
I


19-673
phenyl
Me
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


19-693
3-cyanophenyl
Me
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


19-694
4-cyanophenyl
Me
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


19-709
2-chloropyridin-3-yl
Me
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


19-751
phenyl
Me
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


19-771
3-cyanophenyl
Me
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


19-772
4-cyanophenyl
Me
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


19-787
2-chloropyndin-3-yl
Me
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


19-829
phenyl
Me
Me
N
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


19-849
3-cyanophenyl
Me
Me
N
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


19-850
4-cyanophenyl
Me
Me
N
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


19-865
2-chloropyridin-3-yl
Me
Me
N
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


19-907
phenyl
Me
Me
N
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


19-927
3-cyanophenyl
Me
Me
N
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


19-928
4-cyanophenyl
Me
Me
N
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


19-943
2-chloropyridin-3-yl
Me
Me
N
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


19-985
phenyl
Me
Me
N
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


19-1005
3-cyanophenyl
Me
Me
N
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


19-1006
4-cyanophenyl
Me
Me
N
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


19-1021
2-chloropyridin-3-yl
Me
Me
N
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


19-1063
phenyl
Me
Me
N
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


19-1083
3-cyanophenyl
Me
Me
N
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


19-1084
4-cyanophenyl
Me
Me
N
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


19-1099
2-chloropyridin-3-yl
Me
Me
N
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


19-1337
phenyl
Me
Me
N
H
H
H
F
H
heptafluoroisopropyl
H
CF3


19-1338
phenyl
Me
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


19-1349
3-iodophenyl
Me
Me
N
H
H
H
Cl
H
pentafluoroethyl
H
CF3


19-1350
4-iodophenyl
Me
Me
N
H
H
H
Cl
H
pentafluoroethyl
H
CF3


19-1352
(3-trifluoromethyl)phenyl
Et
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


19-1353
(4-trifluoromethyl)phenyl
Me
Et
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


19-1357
2-cyanophenyl
Me
Me
N
H
H
H
Cl
H
pentafluoroethyl
H
C2F5


19-1358
3-cyanophenyl
Me
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


19-1359
4-cyanophenyl
Me
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


19-1362
2,4-dichlorophenyl
Me
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
C2F5


19-1363
2-chloro-4-fluorophenyl
n-Pr
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


19-1365
4-bromo-2-chlorophenyl
Me
n-Pr
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


19-1366
2-bromo-4-chlorophenyl
Me
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


19-1373
2-fluoropyridin-3-yl
Me
Me
N
H
H
H
Cl
H
pentafluoroethyl
H
CF3


19-1374
2-chloropyridin-3-yl
Me
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


19-1378
2-nitropyridin-3-yl
Me
i-Pr
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


19-1380
6-fluoropyridin-3-yl
i-Pr
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


19-1387
5-fluoropyridin-3-yl
Me
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
C2F5


19-1389
5-bromopyridin-3-yl
Me
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


19-1390
5-iodopyridin-3-yl
Me
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
i-C3F7


19-1392
5-nitropyridin-3-yl
Me
Me
N
H
H
H
Cl
H
pentafluoroethyl
H
CF3


19-1393
5-cyanopyridin-3-yl
Me
CH2CH═CH2
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


19-1394
4-fluoropyridin-3-yl
Me
Me
N
H
H
H
Cl
H
pentafluoroethyl
H
CF3


19-1396
4-bromopyridin-3-yl
CH2CH═CH2
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


19-1397
4-iodopyridin-3-yl
Me
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
i-C3F7


19-1400
4-cyanopyridin-3-yl
Me
CN
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


19-1403
pyridin-4-yl
CN
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


19-1415
4-cyanopyridin-2-yl
Me
Me
N
H
H
H
Cl
H
pentafluoroethyl
H
CF3


19-1416
phenyl
Me
Me
N
H
H
H
F
H
nonafluoro-2-butyl
H
CF3


19-1417
phenYI
Me
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


19-1425
3-bromophenyl
CH2C≡CH
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


19-1429
4-iodophenyl
Me
CH2C≡CH
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


19-1430
(2-trifluoromethyl)phenyl
Me
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


19-1432
(4-trifluoromethyl)phenyl
NH2
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


19-1436
2-cyanophenyl
Me
NH2
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


19-1437
3-cyanophenyl
Me
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


19-1438
4-cyanophenyl
Me
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


19-1442
2-chloro-4-fluorophenyl
Me
C(O)OMe
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


19-1445
2-bromo-4-chlorophenyl
C(O)OMe
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


19-1447
2-chloro-4-nitrophenyl
Me
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


19-1453
2-chloropyridin-3-yl
Me
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


19-1464
6-nitropyridin-3-yl
Me
C(O)OEt
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


19-1466
5-fluoropyridin-3-yl
C(O)OEt
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


19-1468
5-bromopyridin-3-yl
Me
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
n-C3F7


19-1469
5-iodopyridin-3-yl
Me
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


19-1472
5-cyanopyridin-3-yl
Me
C(O)C(O)Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


19-1473
4-fluoropyridin-3-yl
Me
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


19-1475
4-bromopyridin-3-yl
C(O)C(O)Me
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


19-1477
4-(trifluoromethyl)pyridin-3-yl
Me
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
n-C3F7


19-1478
4-nitropyridin-3-yl
C(O)C(O)Et
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


19-1479
4-cyanopyridin-3-yl
Me
C(O)C(O)Et
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


19-1484
3-bromopyridin-4-yl
Me
C(O)Et
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


19-1491
4-bromopyridin-2-yl
Me
C(O)Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


19-1492
5-iodopyridin-2-yl
C(O)Me
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


19-1494
4-cyanopyridin-2-yl
C(O)Et
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


19-1495
phenyl
Me
Me
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


19-1496
2-fluorophenyl
Me
Me
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


19-1509
(3-trifluoromethyl)phenyl
S(O)2Me
Me
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


19-1514
2-cyanophenyl
Me
S(O)2Me
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


19-1515
3-cyanophenyl
Me
Me
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


19-1516
4-cyanophenyl
Me
Me
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


19-1523
2-bromo-4-chlorophenyl
Me
S(O)2Et
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


19-1527
4-cyano-2-fluorophenyl
S(O)2Et
Me
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


19-1531
2-chloropyridin-3-yl
Me
Me
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


19-1542
6-nitropyridin-3-yl
CH2Ph
Me
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


19-1546
5-bromopyridin-3-yl
Me
CH2Ph
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


19-1551
4-fluoropyridin-3-yl
CH2(3-Py)
Me
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


19-1556
4-nitropyridin-3-yl
Me
CH2(3-Py)
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


19-1570
5-iodopyridin-2-yl
Me
CH2(3-Py—N-
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3





oxide)


19-1572
4-cyanopyridin-2-yl
CH2(3-Py—N-
Me
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3




oxide)


19-1573
phenyl
Me
Me
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


19-1574
2-fluorophenyl
Me
Me
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


19-1593
3-cyanophenyl
Me
Me
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


19-1594
4-cyanophenyl
Me
Me
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


19-1600
4-bromo-2-chlorophenyl
Et
Me
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


19-1603
2-chloro-4-nitrophenyl
Me
Et
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


19-1609
2-chloropyridin-3-yl
Me
Me
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


19-1626
5-(trifluoromethyl)pyridin-3-yl
CN
Me
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


19-1627
5-nitropyridin-3-yl
Me
CN
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


19-1651
phenyl
Me
Me
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


19-1652
2-fluorophenyl
Me
Me
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


19-1671
3-cyanophenyl
Me
Me
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


19-1672
4-cyanophenyl
Me
Me
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


19-1687
2-chloropyridin-3-yl
Me
Me
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


19-1700
5-fluoropyridin-3-yl
C(O)Me
Me
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


19-1705
5-nitropyridin-3-yl
Me
C(O)Me
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


19-1729
phenyl
Me
Me
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


19-1730
2-fluorophenyl
Me
Me
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


19-1749
3-cyanophenyl
Me
Me
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


19-1750
4-cyanophenyl
Me
Me
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


19-1765
2-chloropyridin-3-yl
Me
Me
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


19-2003
phenyl
Me
Me
N
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


19-2034
2-chloropyridin-3-yl
Me
Me
N
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


19-2059
phenyl
Me
Me
N
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


19-2090
2-chloropyridin-3-yl
Me
Me
N
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


19-2115
phenyl
Me
Me
N
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


19-2146
2-chloropyridin-3-yl
Me
Me
N
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


19-2171
phenol
Me
Me
N
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


19-2202
2-chloropyridin-3-yl
Me
Me
N
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


19-2227
phenyl
Me
Me
N
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


19-2247
3-cyanophenyl
Me
Me
N
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


19-2248
4-cyanophenyl
Me
Me
N
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


19-2263
2-chloropyridin-3-yl
Me
Me
N
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


19-2295
phenyl
Me
Me
N
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


19-2315
3-cyanophenyl
Me
Me
N
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


19-2316
4-cyanophenyl
Me
Me
N
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


19-2331
2-chloropyridin-3-yl
Me
Me
N
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


19-2559
phenyl
Me
Me
N-oxide
H
H
H
F
H
heptafluoroisopropyl
H
F


19-2560
3-cyanophenyl
Me
Me
N-oxide
H
H
H
F
H
heptafluoroisopropyl
H
F


19-2561
4-cyanophenyl
Me
Me
N-oxide
H
H
H
F
H
heptafluoroisopropyl
H
F


19-2562
2-chloropyridin-3-yl
Me
Me
N-oxide
H
H
H
F
H
heptafluoroisopropyl
H
F


19-2563
phenyl
Me
Me
N-oxide
H
H
H
F
H
nonafluoro-2-butyl
H
F


19-2564
3-cyanophenyl
Me
Me
N-oxide
H
H
H
F
H
nonafluoro-2-butyl
H
F


19-2565
4-cyanophenyl
Me
Me
N-oxide
H
H
H
F
H
nonafluoro-2-butyl
H
F


19-2566
2-chloropyridin-3-yl
Me
Me
N-oxide
H
H
H
F
H
nonafluoro-2-butyl
H
F


19-2567
phenyl
Me
Me
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


19-2587
3-cyanophenyl
Me
Me
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


19-2588
4-cyanophenyl
Me
Me
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


19-2603
2-chloropyridin-3-yl
Me
Me
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


19-2645
phenyl
Me
Me
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


19-2665
3-cyanophenyl
Me
Me
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


19-2666
4-cyanophenyl
Me
Me
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


19-2681
2-chloropyridin-3-yl
Me
Me
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


19-2723
phenyl
Me
Me
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
Br


19-2743
3-cyanophenyl
Me
Me
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
Br


19-2744
4-cyanophenyl
Me
Me
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
Br


19-2759
2-chloropyridin-3-yl
Me
Me
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
Br


19-2801
phenyl
Me
Me
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


19-2821
3-cyanophenyl
Me
Me
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


19-2822
4-cyanophenyl
Me
Me
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


19-2837
2-chloropyridin-3-yl
Me
Me
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


19-2879
phenyl
Me
Me
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
I


19-2899
3-cyanophenyl
Me
Me
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
I


19-2900
4-cyanophenyl
Me
Me
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
I


19-2915
2-chloropyridin-3-yl
Me
Me
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
I


19-2957
phenyl
Me
Me
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
I


19-2977
3-cyanophenyl
Me
Me
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
I


19-2978
4-cyanophenyl
Me
Me
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
I


19-2993
2-chloropyridin-3-yl
Me
Me
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
I


19-3231
phenyl
Me
Me
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


19-3251
3-cyanophenyl
Me
Me
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


19-3252
4-cyanophenyl
Me
Me
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


19-3267
2-chloropyridin-3-yl
Me
Me
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


19-3309
phenyl
Me
Me
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


19-3329
3-cyanophenyl
Me
Me
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


19-3330
4-cyanophenyl
Me
Me
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


19-3345
2-chloropyridin-3-yl
Me
Me
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


19-3387
phenyl
Me
Me
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


19-3407
3-cyanophenyl
Me
Me
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


19-3408
4-cyanophenyl
Me
Me
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


19-3423
2-chloropyridin-3-yl
Me
Me
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


19-3465
phenyl
Me
Me
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


19-3485
3-cyanophenyl
Me
Me
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


19-3486
4-cyanophenyl
Me
Me
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


19-3501
2-chloropyridin-3-yl
Me
Me
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


19-3543
phenyl
Me
Me
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


19-3563
3-cyanophenyl
Me
Me
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


19-3564
4-cyanophenyl
Me
Me
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


19-3579
2-chloropyridin-3-yl
Me
Me
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


19-3621
phenyl
Me
Me
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


19-3641
3-cyanophenyl
Me
Me
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


19-3642
4-cyanophenyl
Me
Me
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


19-3657
2-chloropyridin-3-yl
Me
Me
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


19-3895
phenyl
Me
Me
N-oxide
H
H
H
F
H
heptafluoroisopropyl
H
CF3


19-3896
phenyl
Me
Me
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


19-3916
3-cyanophenyl
Me
Me
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


19-3917
4-cyanophenyl
Me
Me
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


19-3932
2-chloropyridin-3-yl
Me
Me
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


19-3974
phenyl
Me
Me
N-oxide
H
H
H
F
H
nonafluoro-2-butyl
H
CF3


19-3975
phenyl
Me
Me
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


19-3995
3-cyanophenyl
Me
Me
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


19-3996
4-cyanophenyl
Me
Me
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


19-4011
2-chloropyridin-3-yl
Me
Me
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


19-4053
phenyl
Me
Me
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


19-4073
3-cyanophenyl
Me
Me
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


19-4074
4-cyanophenyl
Me
Me
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


19-4089
2-chloropyridin-3-yl
Me
Me
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


19-4131
phenyl
Me
Me
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


19-4151
3-cyanophenyl
Me
Me
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


19-4152
4-cyanophenyl
Me
Me
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


19-4167
2-chloropyridin-3-yl
Me
Me
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


19-4209
phenyl
Me
Me
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


19-4229
3-cyanophenyl
Me
Me
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


19-4230
4-cyanophenyl
Me
Me
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


19-4245
2-chloropyridin-3-yl
Me
Me
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


19-4287
phenyl
Me
Me
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


19-4307
3-cyanophenyl
Me
Me
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


19-4308
4-cyanophenyl
Me
Me
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


19-4323
2-chloropyridin-3-yl
Me
Me
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


19-4561
phenyl
Me
Me
N-oxide
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


19-4592
2-chloropyridin-3-yl
Me
Me
N-oxide
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


19-4617
phenyl
Me
Me
N-oxide
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


19-4648
2-chloropyridin-3-yl
Me
Me
N-oxide
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


19-4673
phenyl
Me
Me
N-oxide
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


19-4704
2-chloropyridin-3-yl
Me
Me
N-oxide
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


19-4729
phenyl
Me
Me
N-oxide
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


19-4760
2-chloropyridin-3-yl
Me
Me
N-oxide
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


19-4785
phenyl
Me
Me
N-oxide
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


19-4805
3-cyanophenyl
Me
Me
N-oxide
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


19-4806
4-cyanophenyl
Me
Me
N-oxide
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


19-4821
2-chloropyridin-3-yl
Me
Me
N-oxide
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


19-4853
phenyl
Me
Me
N-oxide
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


19-4873
3-cyanophenyl
Me
Me
N-oxide
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


19-4874
4-cyanophenyl
Me
Me
N-oxide
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


19-4889
2-chloropyridrn-3-yl
Me
Me
N-oxide
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3











embedded image





















TABLE 20





compound














number
Q1
R1
R2
A
X2
X3
X4
Y1
Y2
Y3
Y4
Y5







20-9
3-bromophenyl
H
Et
N
H
H
H
Cl
F
heptafluoroisopropyl
F
Cl


20-39
2-iodopyridin-3-yl
H
H
N
H
H
H
Cl
Me
nonafluoro-2-butyl
Me
I


20-152
3-bromophenyl
H
Et
N
H
H
H
Cl
F
heptafluoroisopropyl
F
OCF3


20-182
2-iodopyridin-3-yl
H
H
N
H
H
H
Cl
Me
nonafluoro-2-butyl
Me
OCF3


20-287
phenyl
H
H
N
H
H
H
Cl
F
heptafluoroisopropyl
H
CF3


20-288
2-fluorophenyl
Me
H
N
H
H
H
Cl
H
heptafluoroisopropyl
F
CF3


20-289
3-fluorophenyl
H
Me
N
H
H
H
Cl
Cl
heptafluoroisopropyl
H
CF3


20-290
4-fluorophenyl
Me
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
Cl
CF3


20-291
2-chlorophenyl
H
H
N
H
H
H
F
Br
heptafluoroisopropyl
H
CF3


20-292
3-chlorophenyl
H
H
N
H
H
H
Cl
H
heptafluoroisopropyl
Br
CF3


20-293
4-chlorophenyl
Et
H
N
H
H
H
Cl
I
heptafluoroisopropyl
H
C2F5


20-294
2-bromophenyl
H
H
N
H
H
H
Cl
H
heptafluoroisopropyl
I
CF3


20-295
3-bromophenyl
H
Et
N
H
H
H
Cl
F
heptafluoroisopropyl
F
CF3


20-296
4-bromophenyl
H
H
N
H
H
H
Cl
F
heptafluoroisopropyl
Cl
CF3


20-297
2-iodophenyl
H
H
N
H
H
H
Cl
F
heptafluoroisopropyl
Br
CF3


20-298
3-iodophenyl
Et
Et
N
H
H
H
Cl
F
pentafluoroethyl
I
C2F5


20-299
4-iodophenyl
H
H
N
H
H
H
Cl
Cl
pentafluoroethyl
F
CF3


20-300
(2-trifluoromethyl)phenyl
H
H
N
H
H
H
Cl
Cl
heptafluoroisopropyl
Cl
CF3


20-301
(3-trifluoromethyl)phenyl
n-Pr
H
N
H
H
H
Cl
Cl
heptafluoroisopropyl
Br
CF3


20-302
(4-trifluoromethyl)phenyl
H
H
N
H
H
H
Cl
Cl
heptafluoroisopropyl
I
n-C3F7


20-303
2-nitrophenyl
H
n-Pr
N
H
H
H
Cl
Br
heptafluoroisopropyl
F
CF3


20-304
3-nitrophenyl
H
H
N
H
H
H
Cl
Br
heptafluoroisopropyl
Cl
CF3


20-305
4-nitrophenyl
H
H
N
H
H
H
Cl
Br
heptafluoroisopropyl
Br
CF3


20-306
2-cyanophenyl
n-Pr
n-Pr
N
H
H
H
Cl
Br
pentafluoroethyl
I
CF3


20-307
3-cyanophenyl
H
H
N
H
H
H
F
I
nonafluoro-2-butyl
F
CF3


20-308
4-cyanophenyl
H
H
N
H
H
H
Cl
I
nonafluoro-2-butyl
Cl
CF3


20-309
2,6-difluorophenyl
H
H
N
H
H
H
Cl
I
nonafluoro-2-butyl
Br
CF3


20-310
3,4-dichlorophenyl
H
H
N
H
H
H
Cl
I
nonafluoro-2-butyl
I
CF3


20-311
2,4-dichlorophenyl
H
H
N
H
H
H
Cl
Me
nonafluoro-2-butyl
H
CF3


20-312
2-chloro-4-fluorophenyl
H
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
Me
CF3


20-313
2-chloro-4,5-difluorophenyl
i-Pr
H
N
H
H
H
Cl
Et
nonafluoro-2-butyl
H
CF3


20-314
4-bromo-2-chlorophenyl
H
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
Et
CF3


20-315
2-bromo-4-chlorophenyl
H
H
N
H
H
H
Cl
n-Pr
nonafluoro-2-butyl
H
CF3


20-316
2-bromo-4-fluorophenyl
H
i-Pr
N
H
H
H
Cl
H
nonafluoro-2-butyl
n-Pr
CF3


20-317
2-chloro-4-nitrophenyl
i-Pr
i-Pr
N
H
H
H
Cl
i-Pr
nonafluoro-2-butyl
H
CF3


20-318
3,5-dicyanophenyl
H
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
i-Pr
CF3


20-319
4-cyano-2-fluorophenyl
H
H
N
H
H
H
Cl
n-Bu
nonafluoro-2-butyl
H
CF3


20-320
2-chloro-4-cyanophenyl
H
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
n-Bu
CF3


20-321
pyridin-3-yl
H
H
N
H
H
H
Cl
i-Bu
nonafluoro-2-butyl
H
CF3


20-322
2-fluoropyridin-3-yl
H
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
i-Bu
CF3


20-323
2-chloropyridin-3-yl
H
H
N
H
H
H
Cl
s-Bu
nonafluoro-2-butyl
H
C2F5


20-324
2-bromopyridin-3-yl
H
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
s-Bu
CF3


20-325
2-iodopyridin-3-yl
H
H
N
H
H
H
Cl
Me
nonafluoro-2-butyl
Me
n-C3F7


20-326
2-(trifluoromethyl)pyridin-
H
H
N
H
H
H
Cl
Me
nonafluoro-2-butyl
Et
i-C3F7



3-yl


20-327
2-nitropyridin-3-yl
C(O)Me
H
N
H
H
H
Cl
Me
nonafluoro-2-butyl
n-Pr
CF3


20-328
2-cyanopyridin-3-yl
H
H
N
H
H
H
Cl
Me
nonafluoro-2-butyl
i-Pr
CF3


20-329
6-fluoropyridin-3-yl
H
H
N
H
H
H
Cl
Me
nonafluoro-2-butyl
n-Bu
CF3


20-330
6-chloropyridin-3-yl
H
H
N
H
H
H
Cl
Me
nonafluoro-2-butyl
i-Bu
CF3


20-331
6-bromopyridin-3-yl
H
C(O)Me
N
H
H
H
Cl
Me
nonafluoro-2-butyl
s-Bu
CF3


20-332
6-iodopyridin-3-yl
H
H
N
H
H
H
Cl
Et
nonafluoro-2-butyl
Me
n-C3F7


20-333
6-(trifluoromethyl)pyridin-
H
H
N
H
H
H
Cl
Et
nonafluoro-2-butyl
Et
i-C3F7



3-yl


20-334
6-nitropyridin-3-yl
C(O)Me
C(O)Me
N
H
H
H
Cl
Et
nonafluoro-2-butyl
n-Pr
CF3


20-335
6-cyanopyridir-3-yl
H
H
N
H
H
H
Cl
Et
nonafluoro-2-butyl
i-Pr
CF3


20-336
phenyl
H
H
N
H
H
H
Br
Et
heptafluoroisopropyl
n-Bu
CF3


20-337
5-fluoropyridin-3-yl
H
H
N
H
H
H
Br
Et
heptafluoroisopropyl
i-Bu
CF3


20-338
5-chloropyridin-3-yl
H
H
N
H
H
H
Br
Et
heptafluoroisopropyl
s-Bu
CF3


20-339
5-bromopyridin-3-yl
H
H
N
H
H
H
Br
n-Pr
heptafluoroisopropyl
Me
CF3


20-340
5-iodopyridin-3-yl
H
H
N
H
H
H
Br
n-Pr
heptafluoroisopropyl
Et
CF3


20-341
5-(trifluoromethyl)pyridin-
Me
Et
N
H
H
H
Br
n-Pr
pentafluoroethyl
n-Pr
CF3



3-yl


20-342
5-nitropyridin-3-yl
H
H
N
H
H
H
Br
n-Pr
heptafluoroisopropyl
i-Pr
CF3


20-343
5-cyanopyridin-3-yl
H
H
N
H
H
H
Br
n-Pr
pentafluoroethyl
n-Bu
CF3


20-344
4-fluoropyridin-3-yl
H
H
N
H
H
H
Br
n-Pr
heptafluoroisopropyl
i-Bu
CF3


20-345
4-chloropyridin-3-yl
H
H
N
H
H
H
Br
n-Pr
heptafluoroisopropyl
s-Bu
CF3


20-346
4-bromopyridin-3-yl
Me
n-Pr
N
H
H
H
Br
i-Pr
heptafluoroisopropyl
Me
CF3


20-347
4-iodopyridin-3-yl
H
H
N
H
H
H
Br
i-Pr
heptafluoroisopropyl
Et
CF3


20-348
4-(trifluoromethyl)pyridin-
H
H
N
H
H
H
Br
i-Pr
heptafluoroisopropyl
n-Pr
CF3



3-yl


20-349
4-nitropyridin-3-yl
H
H
N
H
H
H
Br
i-Pr
heptafluoroisopropyl
i-Pr
CF3


20-350
4-cyanopyridin-3-yl
H
H
N
H
H
H
Br
i-Pr
heptafluoroisopropyl
n-Bu
CF3


20-351
2,6-dichloropyridin-3-yl
H
H
N
H
H
H
Br
i-Pr
heptafluoroisopropyl
i-Bu
CF3


20-352
pyridin-3-yl N-oxide
Me
i-Pr
N
H
H
H
Br
i-Pr
heptafluoroisopropyl
s-Bu
CF3


20-353
pyridin-4-yl
H
H
N
H
H
H
Br
n-Bu
heptafluoroisopropyl
Me
CF3


20-354
2-chloropyridin-4-yl
H
H
N
H
H
H
Br
n-Bu
heptafluoroisopropyl
Et
CF3


20-355
3-bromopyridin-4-yl
H
H
N
H
H
H
Br
n-Bu
heptafluoroisopropyl
n-Pr
CF3


20-356
3,5-dichloropyridin-4-yl
H
H
N
H
H
H
Br
n-Bu
nonafluoro-2-butyl
i-Pr
CF3


20-357
3-(trifluoromethyl)pyridin-
H
H
N
H
H
H
Br
n-Bu
nonafluoro-2-butyl
n-Bu
CF3



4-yl


20-358
2,6-dicyanopyridin-4-yl
H
H
N
H
H
H
Br
n-Bu
nonafluoro-2-butyl
i-Bu
CF3


20-359
pyridin-4-yl N-oxide
Me
C(O)Me
N
H
H
H
Br
n-Bu
nonafluoro-2-butyl
s-Bu
CF3


20-360
pyridin-2-yl
H
H
N
H
H
H
Br
i-Bu
nonafluoro-2-butyl
Me
CF3


20-361
3-chloropyridin-2-yl
H
H
N
H
H
H
Br
i-Bu
nonafluoro-2-butyl
Et
CF3


20-362
4-bromopyridin-2-yl
H
H
N
H
H
H
Br
i-Bu
nonafluoro-2-butyl
n-Pr
CF3


20-363
5-iodopyridin-2-yl
H
H
N
H
H
H
Br
i-Bu
nonafluoro-2-butyl
i-Pr
CF3


20-364
6-chloropyridin-2-yl
H
H
N
H
H
H
Br
i-Bu
nonafluoro-2-butyl
n-Bu
CF3


20-365
4-cyanopyridin-2-yl
H
H
N
H
H
H
Br
i-Bu
nonafluoro-2-butyl
n-Bu
CF3


20-366
phenyl
H
H
N
H
H
H
Br
i-Bu
nonafluoro-2-butyl
s-Bu
C2F5


20-367
2-fluorophenyl
H
H
N
H
H
H
Br
s-Bu
nonafluoro-2-butyl
Me
CF3


20-368
3-fluorophenyl
H
H
N
H
H
H
Br
s-Bu
nonafluoro-2-butyl
Et
CF3


20-369
4-fluorophenyl
H
H
N
H
H
H
Br
s-Bu
nonafluoro-2-butyl
n-Pr
CF3


20-370
2-chlorophenyl
H
H
N
H
H
H
Br
s-Bu
nonafluoro-2-butyl
i-Pr
CF3


20-371
3-chlorophenyl
H
H
N
H
H
H
Br
s-Bu
nonafluoro-2-butyl
n-Bu
CF3


20-372
4-chlorophenyl
H
H
N
H
H
H
Br
s-Bu
nonafluoro-2-butyl
i-Bu
CF3


20-373
2-bromophenyl
Et
Me
N
H
H
H
Br
s-Bu
nonafluoro-2-butyl
s-Bu
CF3


20-374
3-bromophenyl
H
H
N
H
H
H
Br
F
nonafluoro-2-butyl
Me
CF3


20-375
4-bromophenyl
H
H
N
H
H
H
Br
F
nonafluoro-2-butyl
Et
CF3


20-376
2-iodophenyl
H
H
N
H
H
H
Br
F
nonafluoro-2-butyl
n-Pr
CF3


20-377
3-iodophenyl
H
H
N
H
H
H
Br
F
nonafluoro-2-butyl
i-Pr
CF3


20-378
4-iodophenyl
H
H
N
H
H
H
Br
F
nonafluoro-2-butyl
n-Bu
CF3


20-379
(2-trifluoromethyl)phenyl
H
H
N
H
H
H
Br
F
nonafluoro-2-butyl
i-Bu
CF3


20-380
(3-trifluoromethyl)phenyl
Et
n-Pr
N
H
H
H
Br
F
nonafluoro-2-butyl
s-Bu
CF3


20-381
(4-trifluoromethyl)phenyl
Et
i-Pr
N
H
H
H
Br
Cl
nonafluoro-2-butyl
Me
CF3


20-382
2-nitrophenyl
H
H
N
H
H
H
Br
Cl
nonafluoro-2-butyl
Et
CF3


20-383
phenyl
H
H
N
H
H
H
I
Cl
pentafluoroethyl
n-Pr
CF3


20-384
3-nitrophenyl
H
H
N
H
H
H
I
Cl
heptafluoroisopropyl
i-Pr
CF3


20-385
4-nitrophenyl
H
H
N
H
H
H
I
Cl
heptafluoroisopropyl
n-Bu
CF3


20-386
2-cyanophenyl
Et
C(O)Me
N
H
H
H
I
Cl
heptafluoroisopropyl
i-Bu
CF3


20-387
3-cyanophenyl
H
H
N
H
H
H
I
Cl
heptafluoroisopropyl
s-Bu
CF3


20-388
3-cyanophenyl
H
H
N
H
H
H
I
Br
heptafluoroisopropyl
Me
CF3


20-389
2,6-difluorophenyl
H
H
N
H
H
H
I
Br
heptafluoroisopropyl
Et
CF3


20-390
3,4-dichlorophenyl
H
H
N
H
H
H
I
Br
pentafluoroethyl
n-Pr
CF3


20-391
2,4-dichlorophenyl
H
H
N
H
H
H
I
Br
heptafluoroisopropyl
i-Pr
CF3


20-392
2-chloro-fluorophenyl
H
H
N
H
H
H
I
Br
heptafluoroisopropyl
n-Bu
CF3


20-393
2-chloro-4,5-difluorophenyl
H
H
N
H
H
H
I
Br
heptafluoroisopropyl
i-Bu
CF3


20-394
4-bromo-2-chlorophenyl
H
H
N
H
H
H
I
Br
heptafluoroisopropyl
s-Bu
CF3


20-395
2-bromo-4-chlorophenyl
n-Pr
Me
N
H
H
H
I
I
heptafluoroisopropyl
Me
CF3


20-396
2-bromo-4-flulorophenyl
H
H
N
H
H
H
I
I
heptafluoroisopropyl
Et
CF3


20-397
2-chloro-4-nitrophenyl
n-Pr
Et
N
H
H
H
I
I
heptafluoroisopropyl
n-Pr
CF3


20-398
3,5-dicyanophenyl
H
H
N
H
H
H
I
I
heptafluoroisopropyl
i-Pr
CF3


20-399
4-cyano-2-flulorophenyl
H
H
N
H
H
H
I
I
heptafluoroisopropyl
n-Bu
CF3


20-400
4-cyano-2-cyanophenyl
H
H
N
H
H
H
I
I
heptafluoroisopropyl
i-Bu
CF3


20-401
pyridin-3-yl
H
H
N
H
H
H
I
I
heptafluoroisopropyl
s-Bu
CF3


20-402
2-fluoropyridin-3-yl
H
H
N
H
H
H
I
Me
heptafluoroisopropyl
F
C2F5


20-403
2-chloropyridin-3-yl
H
H
N
H
H
H
I
Me
nonafluoro-2-butyl
Cl
CF3


20-404
2-bromopyridin-3-yl
H
H
N
H
H
H
I
Me
nonafluoro-2-butyl
Br
n-C3F7


20-405
2-iodopyridin-3-yl
H
H
N
H
H
H
I
Me
nonafluoro-2-butyl
I
i-C3F7


20-406
2-(trifluoromethyl)pyridin-
H
H
N
H
H
H
I
Et
nonafluoro-2-butyl
F
CF3



3-yl


20-407
2-nitropyridin-3-yl
H
H
N
H
H
H
I
Et
nonafluoro-2-butyl
Cl
CF3


20-408
2-cyanopyridin-3-yl
H
H
N
H
H
H
I
Et
nonafluoro-2-butyl
Br
CF3


20-409
6-fluoropyridin-3-yl
n-Pr
i-Pr
N
H
H
H
I
Et
nonafluoro-2-butyl
I
C2F5


20-410
6-chloropyridin-3-yl
H
H
N
H
H
H
I
n-Pr
nonafluoro-2-butyl
F
CF3


20-411
6-bromopyridin-3-yl
H
H
N
H
H
H
I
n-Pr
nonafluoro-2-butyl
Cl
CF3


20-412
6-iodopyridin-3-yl
H
H
N
H
H
H
I
n-Pr
nonafluoro-2-butyl
Br
CF3


20-413
6-(trifluoromethyl)pyridin-
H
H
N
H
H
H
I
n-Pr
nonafluoro-2-butyl
I
n-C3F7



3-yl


20-414
6-nitropyridin-3-yl
H
H
N
H
H
H
I
i-Pr
nonafluoro-2-butyl
F
i-C3F7


20-415
5-cyanopyridin-3-yl
H
H
N
H
H
H
I
i-Pr
nonafluoro-2-butyl
Cl
CF3


20-416
5-fluoropyridin-3-yl
n-Pr
C(O)Me
N
H
H
H
I
i-Pr
nonafluoro-2-butyl
Br
CF3


20-417
5-chloropyridin-3-yl
H
H
N
H
H
H
I
i-Pr
nonafluoro-2-butyl
I
CF3


20-418
5-bromopyridin-3-yl
H
H
N
H
H
H
I
n-Bu
nonafluoro-2-butyl
F
CF3


20-419
5-iodopyridin-3-yl
H
H
N
H
H
H
I
n-Bu
nonafluoro-2-butyl
Cl
CF3


20-420
5-(trifluoromethyl)pyridin-
H
H
N
H
H
H
I
n-Bu
nonafluoro-2-butyl
Br
CF3



3-yl


20-421
5-nitropyridin-3-yl
i-Pr
Me
N
H
H
H
I
n-Bu
nonafluoro-2-butyl
I
CF3


20-422
5-cyanopyridin-3-yl
H
H
N
H
H
H
I
i-Bu
nonafluoro-2-butyl
F
CF3


20-423
4-fluoropyridin-3-yl
H
H
N
H
H
H
I
i-Bu
nonafluoro-2-butyl
Cl
CF3


20-424
4-chloropyridin-3-yl
H
H
N
H
H
H
I
i-Bu
nonafluoro-2-butyl
Br
CF3


20-425
4-bromopyridin-3-yl
i-Pr
Et
N
H
H
H
I
i-Bu
nonafluoro-2-butyl
I
CF3


20-426
4-iodopyridin-3-yl
i-Pr
n-Pr
N
H
H
H
I
s-Bu
nonafluoro-2-butyl
F
CF3


20-427
4-(trifluoromethyl)pyridin-
H
H
N
H
H
H
I
s-Bu
nonafluoro-2-butyl
Cl
CF3



3-yl


20-428
4-nitropyridin-3-yl
i-Pr
C(O)Me
N
H
H
H
I
s-Bu
nonafluoro-2-butyl
Br
CF3


20-429
4-cyanopyridin-3-yl
H
H
N
H
H
H
I
s-Bu
nonafluoro-2-butyl
I
CF3


20-438
3-bromophenyl
H
Et
N
H
H
H
OCF3
F
heptafluoroisopropyl
F
OCF3


20-468
2-iodopyridin-3-yl
H
H
N
H
H
H
OCF3
Me
nonafluoro-2-butyl
Me
OCF3


20-581
3-bromophenyl
H
Et
N
H
H
H
OCF3
F
heptafluoroisopropyl
F
CF3


20-611
2-iodopyridin-3-yl
H
H
N
H
H
H
OCF3
Me
nonafluoro-2-butyl
Me
CF3


20-724
3-bromophenyl
H
Et
N
H
H
H
CF3
F
heptafluoroisopropyl
F
CF3


20-754
2-iodopyridin-3-yl
H
H
N
H
H
H
CF3
Me
nonafluoro-2-butyl
Me
CF3


20-887
3-bromophenyl
H
Et
N-oxide
H
H
H
Cl
F
heptafluoroisopropyl
F
Cl


20-897
2-iodopyridin-3-yl
H
H
N-oxide
H
H
H
Cl
Me
nonafluoro-2-butyl
Me
I


20-1010
3-bromophenyl
H
Et
N-oxide
H
H
H
Cl
F
heptafluoroisopropyl
F
OCF3


20-1040
2-iodopyridin-3-yl
H
H
N-oxide
H
H
H
Cl
Me
nonafluoro-2-butyl
Me
OCF3


20-1154
4-bromophenyl
H
H
N-oxide
H
H
H
Cl
F
heptafluoroisopropyl
Cl
CF3


20-1169
2,4-dichlorophenyl
H
H
N-oxide
H
H
H
Cl
Me
nonafluoro-2-butyl
H
CF3


20-1233
4-bromophenyl
H
H
N-oxide
H
H
H
Br
F
nonafluoro-2-butyl
Et
CF3


20-1261
2-chloropyridin-3-yl
H
H
N-oxide
H
H
H
I
Me
nonafluoro-2-butyl
Cl
CF3


20-1296
3-bromophenyl
H
Et
N-oxide
H
H
H
OCF3
F
heptafluoroisopropyl
F
OCF3


20-1326
2-iodopyridin-3-yl
H
H
N-oxide
H
H
H
OCF3
Me
nonafluoro-2-butyl
Me
OCF3


20-1439
3-bromophenyl
H
Et
N-oxide
H
H
H
OCF3
F
heptafluoroisopropyl
F
CF3


20-1469
2-iodopyridin-3-yl
H
H
N-oxide
H
H
H
OCF3
Me
nonafluoro-2-butyl
Me
CF3


20-1582
3-bromophenyl
H
Et
N-oxide
H
H
H
CF3
F
heptafluoroisopropyl
F
CF3


20-1612
2-iodopyridin-3-yl
H
H
N-oxide
H
H
H
CF3
Me
nonafluoro-2-butyl
Me
CF3











embedded image





















TABLE 21





compound














number
Q2
R1
R2
A
X2
X3
X4
Y1
Y2
Y3
Y4
Y5







21-1
2,2,2-trichloroethyl
H
H
N
H
H
H
F
H
heptafluoroisopropyl
H
F


21-2
2,2,2-trichloroethyl
H
H
N
H
H
H
F
H
nonafluoro-2-butyl
H
F


21-13
2,2,2-trichloroethyl
H
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


21-14
2,2,2-tribromoethyl
H
H
N
H
H
H
Cl
H
pentafluoroethyl
H
Cl


21-22
1,3-dichloro-2-propyl
H
H
N
H
H
H
Cl
H
pentafluoroethyl
H
Cl


21-26
4,4,4-trifluoro-n-butyl
H
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


21-42
2,2,2-trichloroethyl
H
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


21-55
4,4,4-trifluoro-n-butyl
H
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


21-71
2,2,2-trichloroethyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
Br


21-74
3-fluoro-n-propyl
H
H
N
H
H
H
Br
H
pentafluoroethyl
H
Br


21-80
1,3-dichloro-2-propyl
H
H
N
H
H
H
Br
H
pentafluoroethyl
H
Br


21-84
4,4,4-trifluoro-n-butyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
Br


21-100
2,2,2-trichloroethyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


21-113
4,4,4-trifluoro-n-butyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


21-129
2,2,2-trichloroethyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
I


21-131
n-propyl
H
H
N
H
H
H
I
H
pentafluoroethyl
H
I


21-138
1,3-dichloro-2-propyl
H
H
N
H
H
H
I
H
pentafluoroethyl
H
I


21-142
4,4,4-trifluoro-n-butyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
I


21-158
2,2,2-trichloroethyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
I


21-171
4,4,4-trifluoro-n-butyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
I


21-177
2,2,2-trichloroethyl
H
H
N
H
H
H
F
H
heptafluoroisopropyl
H
Cl


21-178
2,2,2-trichloroethyl
H
H
N
H
H
H
F
H
heptafluoroisopropyl
H
Br


21-179
2,2,2-trichloroethyl
H
H
N
H
H
H
F
H
heptafluoroisopropyl
H
I


21-180
2,2,2-trichloroethyl
H
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
Br


21-181
2,2,2-trichloroethyl
H
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
I


21-182
2,2,2-trichloroethyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
I


21-183
2,2,2-trichloroethyl
H
H
N
H
H
H
F
H
nonafluoro-2-butyl
H
Cl


21-184
2,2,2-trichloroethyl
H
H
N
H
H
H
F
H
nonafluoro-2-butyl
H
Br


21-185
2,2,2-trichloroethyl
H
H
N
H
H
H
F
H
nonafluoro-2-butyl
H
I


21-186
2,2,2-trichloroethyl
H
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
Br


21-187
2,2,2-trichloroethyl
H
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
I


21-188
2,2,2-trichloroethyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
I


21-189
2,2,2-trichloroethyl
H
H
N
H
H
H
F
H
heptafluoroisopropyl
H
OCF3


21-190
2,2,2-trichloroethyl
H
H
N
H
H
H
F
H
nonafluoro-2-butyl
H
OCF3


21-201
2,2,2-trichloroethyl
H
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


21-202
2,2,2-tribromoethyl
H
H
N
H
H
H
Cl
H
pentafluoroethyl
H
OCF3


21-206
3-bromo-n-propyl
H
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
OC2F5


21-210
1,3-dichloro-2-propyl
H
H
N
H
H
H
Cl
H
pentafluoroethyl
H
OC2F5


21-214
4,4,4-trifluoro-n-butyl
H
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


21-226
2-cyanoethyl
H
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
OC2F5


21-230
2,2,2-trichloroethyl
H
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


21-243
4,4,4-trifluoro-n-butyl
H
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


21-245
s-butyl
H
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
OC2F5


21-254
2-iodoethyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
OC2F5


21-259
2,2,2-trichloroethyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


21-260
2,2,2-tribromoethyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


21-272
4,4,4-trifluoro-n-butyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


21-288
2,2,2-trichloroethyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


21-289
2,2,2-tribromoethyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
OC2F5


21-301
4,4,4-trifluoro-n-butyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


21-317
2,2,2-trichloroethyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


21-321
3-chloro-n-propyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
OC2F5


21-330
4,4,4-trifluoro-n-butyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


21-346
2,2,2-trichloroethyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


21-359
4,4,4-trifluoro-n-butyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


21-363
benzyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
OC2F5


21-365
2,2,2-trichloroethyl
H
H
N
H
H
H
F
H
heptafluoroisopropyl
H
CF3


21-366
2,2,2-trichloroethyl
H
H
N
H
H
H
F
H
nonafluoro-2-butyl
H
CF3


21-373
2-cyanoethyl
H
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
C2F5


21-377
2,2,2-trichloroethyl
H
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


21-378
2,2,2-tribromoethyl
H
H
N
H
H
H
Cl
H
pentafluoroethyl
H
CF3


21-383
i-propyl
H
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


21-390
4,4,4-trifluoro-n-butyl
H
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


21-397
ethyl
H
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


21-406
2,2,2-trichloroethyl
H
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


21-419
4,4,4-trifluoro-n-butyl
H
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


21-425
methyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


21-426
ethyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


21-427
2-fluoroethyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


21-428
2-chloroethyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


21-429
2-bromoethyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


21-430
2-iodoethyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


21-431
2-cyanoethyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
C2F5


21-432
2,2-difluoroethyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


21-433
2,2-dichloroethyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


21-434
2,2,2-trifluoroethyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


21-435
2,2,2-trichloroethyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


21-436
2,2,2-tribromoethyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


21-437
n-propyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


21-438
3-fluoro-n-propyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


21-439
3-chloro-n-propyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


21-440
3-bromo-n-propyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


21-441
i-propyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


21-442
1,2-difluoro-2-propyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
n-C3F7


21-443
1,3-difluoro-2-propyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


21-444
1,3-dichloro-2-propyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


21-445
1-chloro-3-fluoro-2-propyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


21-446
3,3,3-trifluoro-n-propyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


21-447
n-butyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


21-448
4,4,4-trifluoro-n-butyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


21-449
i-butyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


21-450
s-butyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


21-451
vinyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


21-452
benzyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


21-453
phenyl
H
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


21-454
methyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


21-455
ethyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


21-456
2-fluoroethyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


21-457
2-chloroethyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


21-458
2-bromoethyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


21-459
2-iodoethyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


21-460
2-cyanoethyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


21-461
2,2-difluoroethyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


21-462
2,2-dichloroethyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


21-463
2,2,2-trifluoroethyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


21-464
2,2,2-trichloroethyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


21-465
2,2,2-tribromoethyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


21-466
n-propyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


21-467
3-fluoro-n-propyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


21-468
3-chloro-n-propyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


21-469
3-bromo-n-propyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


21-470
i-propyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


21-471
1,2-difluoro-2-propyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


21-472
1,3-difluoro-2-propyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


21-473
1,3-dichloro-2-propyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


21-474
1-chloro-3-fluoro-2-propyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


21-475
3,3,3-trifluoro-n-propyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


21-476
n-butyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


21-477
4,4,4-trifluoro-n-propyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


21-478
i-butyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


21-479
s-butyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


21-480
vinyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


21-481
benzyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


21-482
phenyl
H
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
i-C3F7


21-483
methyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


21-484
ethyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


21-485
2-fluoroethyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


21-486
2-chloroethyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


21-487
2-bromoethyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


21-488
2-iodoethyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


21-489
2-cyanoethyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


21-490
2,2-difluoroethyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


21-491
2,2-dichloroethyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


21-492
2,2,2-trifluoroethyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


21-493
2,2,2-trichloroethyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


21-494
2,2,2-tribromoethyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


21-495
n-propyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


21-496
3-fluoro-n-propyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


21-497
3-chloro-n-propyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


21-498
3-bromo-n-propyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
C2F5


21-499
i-propyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


21-500
1,2-difluoro-2-propyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


21-501
1,3-difluoro-2-propyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


21-502
1,3-dichloro-2-propyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


21-503
1-chloro-3-fluoro-2-propyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


21-504
3,3,3-trifluoro-n-propyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


21-505
n-butyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


21-506
4,4,4-trifluoro-n-butyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


21-507
i-butyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


21-508
s-butyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


21-509
vinyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


21-510
benzyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


21-511
phenyl
H
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


21-512
methyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


21-513
ethyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


21-514
2-fluoroethyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


21-515
2-chloroethyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


21-516
2-bromoethyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


21-517
2-iodoethyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


21-518
2-cyanoethyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


21-519
2,2-difluoroethyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


21-520
2,2-dichloroethyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


21-521
2,2,2-trifluoroethyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


21-522
2,2,2-trichloroethyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


21-523
2,2,2-tribromoethyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


21-524
n-propyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
n-C3F7


21-525
3-fluoro-n-propyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


21-526
3-chloro-n-propyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


21-527
3-bromo-n-propyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


21-528
i-propyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


21-529
1,2-difluoro-2-propyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


21-530
1,3-difluoro-2-propyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


21-531
1,3-dichloro-2-propyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


21-532
1-chloro-3-fluoro-2-propyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


21-533
3,3,3-trifluoro-n-propyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


21-534
n-butyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


21-535
4,4,4-trifluoro-n-butyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


21-536
i-butyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


21-537
s-butyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


21-538
vinyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
i-C3F7


21-539
benzyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


21-540
phenyl
H
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


21-547
2-cyanoethyl
H
H
N
H
H
H
OCF3
H
heptafluoroisopropyl
H
OC2F5


21-551
2,2,2-trichloroethyl
H
H
N
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


21-552
2,2,2-tribromoethyl
H
H
N
H
H
H
OCF3
H
pentafluoroethyl
H
OCF3


21-561
1-chloro-3-fluoro-2-propyl
H
H
N
H
H
H
OC2F5
H
heptafluoroisopropyl
H
OC2F5


21-564
4,4,4-trifluoro-n-butyl
H
H
N
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


21-566
s-butyl
H
H
N
H
H
H
OC2F5
H
heptafluoroisopropyl
H
OCF3


21-576
2-cyanoethyl
H
H
N
H
H
H
OC2F5
H
nonafluoro-2-butyl
H
OCF3


21-580
2,2,2-trichloroethyl
H
H
N
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


21-581
2,2,2-tribromoethyl
H
H
N
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OC2F5


21-592
n-butyl
H
H
N
H
H
H
OC2F5
H
nonafluoro-2-butyl
H
OC2F5


21-593
4,4,4-trifluoro-n-butyl
H
H
N
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


21-605
2-cyanoethyl
H
H
N
H
H
H
CF3
H
heptafluoroisopropyl
H
OC2F5


21-609
2,2,2-trichloroethyl
H
H
N
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


21-610
2,2,2-tribromoethyl
H
H
N
H
H
H
C2F5
H
heptafluoroisopropyl
H
OC2F5


21-621
n-butyl
H
H
N
H
H
H
n-C3F7
H
heptafluoroisopropyl
H
OCF3


21-622
4,4,4-trifluoro-n-butyl
H
H
N
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


21-625
vinyl
H
H
N
H
H
H
i-C3F7
H
heptafluoroisopropyl
H
OCF3


21-633
2-iodoethyl
H
H
N
H
H
H
C2F5
H
nonafluoro-2-butyl
H
OCF3


21-638
2,2,2-trichloroethyl
H
H
N
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


21-640
n-propyl
H
H
N
H
H
H
n-C3F7
H
nonafluoro-2-butyl
H
OCF3


21-644
i-propyl
H
H
N
H
H
H
CF3
H
nonafluoro-2-butyl
H
OC2F5


21-651
4,4,4-trifluoro-n-butyl
H
H
N
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


21-652
i-butyl
H
H
N
H
H
H
i-C3F7
H
nonafluoro-2-butyl
H
OCF3


21-655
benzyl
H
H
N
H
H
H
n-C3F7
H
nonafluoro-2-butyl
H
OC2F5


21-656
phenyl
H
H
N
H
H
H
i-C3F7
H
nonafluoro-2-butyl
H
OC2F5


21-667
2,2,2-trichloroethyl
H
H
N
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


21-670
3-fluoro-n-propyl
H
H
N
H
H
H
C2F5
H
heptafluoroisopropyl
H
CF3


21-673
i-propyl
H
H
N
H
H
H
i-C3F7
H
heptafluoroisopropyl
H
CF3


21-675
1,3-difluoro-2-propyl
H
H
N
H
H
H
CF3
H
pentafluoroethyl
H
CF3


21-679
n-butyl
H
H
N
H
H
H
C2F5
H
heptafluoroisopropyl
H
C2F5


21-680
4,4,4-trifluoro-n-butyl
H
H
N
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


21-681
i-butyl
H
H
N
H
H
H
C2F5
H
heptafluoroisopropyl
H
n-C3F7


21-683
vinyl
H
H
N
H
H
H
n-C3F7
H
heptafluoroisopropyl
H
CF3


21-696
2,2,2-trichloroethyl
H
H
N
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


21-708
n-butyl
H
H
N
H
H
H
C2F5
H
nonafluoro-2-butyl
H
i-C3F7


21-709
4,4,4-trifluoro-n-butyl
H
H
N
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


21-712
vinyl
H
H
N
H
H
H
n-C3F7
H
nonafluoro-2-butyl
H
i-C3F7


21-715
2,2,2-trichloroethyl
H
H
N-oxide
H
H
H
F
H
heptafluoroisopropyl
H
F


21-716
2,2,2-trichloroethyl
H
H
N-oxide
H
H
H
F
H
nonafluoro-2-butyl
H
F


21-727
2,2,2-trichloroethyl
H
H
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


21-756
2,2,2-trichloroethyl
H
H
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


21-785
2,2,2-trichloroethyl
H
H
N-oxtde
H
H
H
Br
H
heptafluoroisopropyl
H
Br


21-814
2,2,2-trichloroethyl
H
H
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


21-843
2,2,2-trichloroethyl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
I


21-872
2,2,2-trichloroethyl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
I


21-894
2,2,2-trichloroethyl
H
H
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
Br


21-903
2,2,2-trichloroethyl
H
H
N-oxide
H
H
H
F
H
heptafluoroisopropyl
H
OCF3


21-904
2,2,2-trichloroethyl
H
H
N-oxide
H
H
H
F
H
nonafluoro-2-butyl
H
OCF3


21-915
2,2,2-trichloroethyl
H
H
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


21-944
2,2,2-trichloroethyl
H
H
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


21-973
2,2,2-trichloroethyl
H
H
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


21-1002
2,2,2-trichloroethyl
H
H
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


21-1031
2,2,2-trichloroethyl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


21-1060
2,2,2-trichloroethyl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


21-1079
2,2,2-trichloroethyl
H
H
N-oxide
H
H
H
F
H
heptafluoroisopropyl
H
CF3


21-1080
2,2,2-trichloroethyl
H
H
N-oxide
H
H
H
F
H
nonafluoro-2-butyl
H
CF3


21-1091
2,2,2-trichloroethyl
H
H
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


21-1120
2,2,2-trichloroethyl
H
H
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


21-1149
2,2,2-trichloroethyl
H
H
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


21-1178
2,2,2-trichloroethyl
H
H
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


21-1207
2,2,2-trichloroethyl
H
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


21-1236
2,2,2-trichloroethyl
H
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


21-1265
2,2,2-trichloroethyl
H
H
N-oxide
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


21-1294
2,2,2-trichloroethyl
H
H
N-oxide
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


21-1323
2,2,2-trichloroethyl
H
H
N-oxide
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


21-1352
2,2,2-trichloroethyl
H
H
N-oxide
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


21-1381
2,2,2-trichloroethyl
H
H
N-oxide
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


21-1410
2,2,2-trichloroethyl
H
H
N-oxide
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3











embedded image





















TABLE 22





compound














number
Q2
R1
R2
A
X2
X3
X4
Y1
Y2
Y3
Y4
Y5







22-1
2,2,2-trichloroethyl
Me
H
N
H
H
H
F
H
heptafluoroisopropyl
H
F


22-2
2,2,2-trichloroethyl
Me
H
N
H
H
H
F
H
nonafluoro-2-butyl
H
F


22-13
2,2,2-trichloroethyl
Me
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


22-42
2,2,2-trichloroethyl
Me
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


22-71
2,2,2-trichloroethyl
Me
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
Br


22-100
2,2,2-trichloroethyl
Me
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


22-129
2,2,2-trichloroethyl
Me
H
N
H
H
H
I
H
heptafluoroisopropyl
H
I


22-158
2,2,2-trichloroethyl
Me
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
I


22-186
2,2,2-trichloroethyl
Me
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
Br


22-189
2,2,2-trichloroethyl
Me
H
N
H
H
H
F
H
heptafluoroisopropyl
H
OCF3


22-190
2,2,2-trichloroethyl
Me
H
N
H
H
H
F
H
nonafluoro-2-butyl
H
OCF3


22-201
2,2,2-trichloroethyl
Me
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


22-230
2,2,2-trichloroethyl
Me
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


22-259
2,2,2-trichloroethyl
Me
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


22-288
2,2,2-trichloroethyl
Me
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


22-317
22,2-trichloroethyl
Me
H
N
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


22-346
22,2-trichloroethyl
Me
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


22-365
2,2,2-trichloroethyl
Me
H
N
H
H
H
F
H
heptafluoroisopropyl
H
CF3


22-366
2,2,2-trichloroethyl
Me
H
N
H
H
H
F
H
nonafluoro-2-butyl
H
CF3


22-373
2-cyanoethyl
Et
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
C2F5


22-377
2,2,2-trichloroethyl
Me
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


22-379
n-propyl
Me
H
N
H
H
H
Cl
H
pentafluoroethyl
H
CF3


22-383
i-propyl
n-Pr
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


22-386
1,3-dichloro-2-propyl
Me
H
N
H
H
H
Cl
H
pentafluoroethyl
H
CF3


22-387
1-chloro-3-fluoro-2-propyl
i-Pr
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


22-390
4,4.4-trifluoro-n-butyl
Me
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


22-391
i-butyl
CH2CH═CH2
H
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


22-397
ethyl
Me
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


22-402
2-cyanoethyl
CN
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


22-406
2,2,2-trichloroethyl
Me
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


22-408
n-propyl
CH2C≡CH
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


22-419
4,4,4-trifluoro-n-butyl
Me
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


22-420
i-butyl
NH2
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


22-431
2-cyanoethyl
Me
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
C2F5


22-435
2,2,2-trichloroethyl
Me
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


22-438
3-fluoro-n-propyl
C(O)OMe
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


22-442
1,2-difluoro-2-propyl
Me
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
n-C3F7


22-448
4,4,4-trifluoro-n-butyl
Me
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


22-451
vinyl
C(O)C(O)OMe
H
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


22-464
2,2,2-trichloroethyl
Me
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


22-466
n-propyl
C(O)OEt
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


22-470
i-propyl
C(O)Me
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


22-477
4,4,4-trifluoro-n-butyl
Me
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


22-482
phenyl
C(O)C(O)OEt
H
N
H
H
H
Br
H
nonafluoro-2-butyl
H
i-C3F7


22-493
2,2,2-trichloroethyl
Me
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


22-498
3-bromo-n-propyl
C(O)Et
H
N
H
H
H
I
H
heptafluoroisopropyl
H
C2F5


22-506
4,4,4-trifluoro-n-butyl
Me
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


22-510
benzyl
S(O)2Me
H
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


22-518
2-cyanoethyl
S(O)2Et
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


22-522
2,2,2-trichloroethyl
Me
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


22-523
2,2,2-tribromoethyl
Me
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


22-524
n-propyl
CH2Ph
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
n-C3F7


22-528
i-propyl
CH2(3-Py)
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


22-535
4,4,4-trifluoro-n-butyl
Me
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


22-537
s-butyl
CH2(3-Py—N-
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3




oxide)


22-538
vinyl
Me
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
i-C3F7


22-539
benzyl
Me
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


22-540
phenyl
Me
H
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


22-551
2,2,2-trichloroethyl
Me
H
N
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


22-580
2,2,2-trichloroethyl
Me
H
N
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


22-609
2,2,2-trichloroethyl
Me
H
N
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


22-638
2,2,2-trichloroethyl
Me
H
N
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


22-667
2,2,2-trichloroethyl
Me
H
N
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


22-696
2,2,2-trichloroethyl
Me
H
N
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


22-715
2,2,2-trichloroethyl
Me
H
N-oxide
H
H
H
F
H
heptafluoroisopropyl
H
F


22-716
2,2,2-trichloroethyl
Me
H
N-oxide
H
H
H
F
H
nonafluoro-2-butyl
H
F


22-727
2,2,2-trichloroethyl
Me
H
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


22-756
2,2,2-trichloroethyl
Me
H
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


22-785
2,2,2-trichloroethyl
Me
H
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
Br


22-814
2,2,2-trichloroethyl
Me
H
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


22-843
2,2,2-trichloroethyl
Me
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
I


22-872
2,2,2-trichloroethyl
Me
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
I


22-894
2,2,2-trichloroethyl
Me
H
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
Br


22-903
2,2,2-trichloroethyl
Me
H
N-oxide
H
H
H
F
H
heptafluoroisopropyl
H
OCF3


22-904
2,2,2-trichloroethyl
Me
H
N-oxide
H
H
H
F
H
nonafluoro-2-butyl
H
OCF3


22-915
2,2,2-trichloroethyl
Me
H
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


22-944
2,2,2-trichloroethyl
Me
H
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


22-973
2,2,2-trichloroethyl
Me
H
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


22-1002
2,2,2-trichloroethyl
Me
H
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


22-1031
2,2,2-trichloroethyl
Me
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


22-1060
2,2,2-trichloroethyl
Me
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


22-1079
2,2,2-trichloroethyl
Me
H
N-oxide
H
H
H
F
H
heptafluoroisopropyl
H
CF3


22-1080
2,2,2-trichloroethyl
Me
H
N-oxide
H
H
H
F
H
nonafluoro-2-butyl
H
CF3


22-1091
2,2,2-trichloroethyl
Me
H
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


22-1120
2,2,2-trichloroethyl
Me
H
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


22-1149
2,2,2-trichloroethyl
Me
H
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


22-1178
2,2,2-trichloroethyl
Me
H
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


22-1207
2,2,2-trichloroethyl
Me
H
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


22-1236
2,2,2-trichloroethyl
Me
H
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


22-1265
2,2,2-trichloroethyl
Me
H
N-oxide
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


22-1294
2,2,2-trichloroethyl
Me
H
N-oxide
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


22-1323
2,2,2-trichloroethyl
Me
H
N-oxide
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


22-1352
2,2,2-trichloroethyl
Me
H
N-oxide
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


22-1381
2,2,2-trichloroethyl
Me
H
N-oxide
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


22-1410
2,2,2-trichloroethyl
Me
H
N-oxide
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3











embedded image





















TABLE 23





compound














number
Q2
R1
R2
A
X2
X3
X4
Y1
Y2
Y3
Y4
Y5







23-1
2,2,2-trichloroethyl
H
Me
N
H
H
H
F
H
heptafluoroisopropyl
H
F


23-2
2,2,2-trichloroethyl
H
Me
N
H
H
H
F
H
nonafluoro-2-butyl
H
F


23-13
2,2,2-trichloroethyl
H
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


23-42
2,2,2-trichloroethyl
H
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


23-100
2,2,2-trichloroethyl
H
Me
N
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


23-129
2,2,2-trichloroethyl
H
Me
N
H
H
H
I
H
heptafluoroisopropyl
H
I


23-158
2,2,2-trichloroethyl
H
Me
N
H
H
H
I
H
nonafluoro-2-butyl
H
I


23-186
2,2,2-trichloroethyl
H
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
Br


23-189
2,2,2-trichloroethyl
H
Me
N
H
H
H
F
H
heptafluoroisopropyl
H
OCF3


23-190
2,2,2-trichloroethyl
H
Me
N
H
H
H
F
H
nonafluoro-2-butyl
H
OCF3


23-201
2,2,2-trichloroethyl
H
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


23-230
2,2,2-trichloroethyl
H
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


23-259
2,2,2-trichloroethyl
H
Me
N
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


23-288
2,2,2-trichloroethyl
H
Me
N
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


23-317
2,2,2-trichloroethyl
H
Me
N
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


23-346
2,2,2-trichloroethyl
H
Me
N
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


23-365
2,2,2-trichloroethyl
H
Me
N
H
H
H
F
H
heptafluoroisopropyl
H
CF3


23-366
2,2,2-trichloroethyl
H
Me
N
H
H
H
F
H
nonafluoro-2-butyl
H
CF3


23-373
2-cyanoethyl
H
Et
N
H
H
H
Cl
H
heptafluoroisopropyl
H
C2F5


23-377
2,2,2-trichloroethyl
H
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


23-379
n-propyl
H
Me
N
H
H
H
Cl
H
pentafluoroethyl
H
CF3


23-383
i-propyl
H
n-Pr
N
H
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


23-386
1,3-dichloro-2-propyl
H
Me
N
H
H
H
Cl
H
pentafluoroethyl
H
CF3


23-387
1-chloro-3-fluoro-2-propyl
H
i-Pr
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


23-391
i-butyl
H
CH2CH═CH2
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


23-397
ethyl
H
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


23-402
2-cyanoethyl
H
CN
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


23-406
2,2,2-trichloroethyl
H
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


23-408
n-propyl
H
CH2C≡CH
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


23-420
i-butyl
H
NH2
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


23-431
2-cyanoethyl
H
Me
N
H
H
H
Br
H
heptafluoroisopropyl
H
C2F5


23-435
2,2,2-trichloroethyl
H
Me
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


23-437
n-propyl
H
C(O)OMe
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


23-442
1,2-difluoro-2-propyl
H
Me
N
H
H
H
Br
H
heptafluoroisopropyl
H
n-C3F7


23-448
4,4,4-trifluoro-n-butyl
H
Me
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


23-451
vinyl
H
C(O)C(O)OMe
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


23-464
2,2,2-trichloroethyl
H
Me
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


23-466
n-propyl
H
C(O)OEt
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


23-470
i-propyl
H
C(O)Me
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


23-477
4,4,4-trifluoro-n-butyl
H
Me
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


23-482
phenyl
H
C(O)C(O)OEt
N
H
H
H
Br
H
nonafluoro-2-butyl
H
i-C3F7


23-493
2,2,2-trichloroethyl
H
Me
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


23-498
3-bromo-n-propyl
H
C(O)Et
N
H
H
H
I
H
heptafluoroisopropyl
H
C2F5


23-506
4,4,4-trifluoro-n-butyl
H
Me
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


23-510
benzyl
H
S(O)2Me
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


23-518
2-cyanoethyl
H
S(O)2Et
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


23-522
2,2,2-trichloroethyl
H
Me
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


23-524
n-propyl
H
CH2Ph
N
H
H
H
I
H
nonafluoro-2-butyl
H
n-C3F7


23-528
i-propyl
H
CH2(3-Py)
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


23-535
4,4,4-trifluoro-n-butyl
H
Me
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


23-537
s-butyl
H
CH2(3-Py—N-
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3





oxide)


23-538
vinyl
H
Me
N
H
H
H
I
H
nonafluoro-2-butyl
H
i-C3F7


23-551
2,2,2-trichloroethyl
H
Me
N
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


23-580
2,2.2-trichloroethyl
H
Me
N
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


23-609
2,2,2-trichloroethyl
H
Me
N
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


23-638
2,2,2-trichloroethyl
H
Me
N
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


23-667
2,2,2-trichloroethyl
H
Me
N
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


23-696
2,2,2-trichloroethyl
H
Me
N
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


23-715
2,2,2-trichloroethyl
H
Me
N-oxide
H
H
H
F
H
heptafluoroisopropyl
H
F


23-716
2,2,2-trichloroethyl
H
Me
N-oxide
H
H
H
F
H
nonafluoro-2-butyl
H
F


23-727
2,2,2-trichloroethyl
H
Me
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


23-756
2,2,2-trichloroethyl
H
Me
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


23-785
2,2,2-trichloroethyl
H
Me
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
Br


23-814
2,2,2-trichloroethyl
H
Me
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


23-843
2,2,2-trichloroethyl
H
Me
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
I


23-872
2,2,2-trichloroethyl
H
Me
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
I


23-895
2,2,2-trichloroethyl
H
Me
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
I


23-903
2,2,2-trichloroethyl
H
Me
N-oxide
H
H
H
F
H
heptafluoroisopropyl
H
OCF3


23-904
2,2,2-trichloroethyl
H
Me
N-oxide
H
H
H
F
H
nonafluoro-2-butyl
H
OCF3


23-915
2,2,2-trichloroethyl
H
Me
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


23-944
2,2,2-trichloroethyl
H
Me
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


23-973
2,2,2-trichloroethyl
H
Me
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


23-1002
2,2,2-trichloroethyl
H
Me
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


23-1031
2,2,2-trichloroethyl
H
Me
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


23-1060
2,2,2-trichloroethyl
H
Me
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


23-1079
2,2,2-trichloroethyl
H
Me
N-oxide
H
H
H
F
H
heptafluoroisopropyl
H
CF3


23-1080
2,2,2-trichloroethyl
H
Me
N-oxide
H
H
H
F
H
nonafluoro-2-butyl
H
CF3


23-1091
2,2,2-trichloroethyl
H
Me
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


23-1120
2,2,2-trichloroethyl
H
Me
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


23-1149
2,2,2-trichloroethyl
H
Me
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


23-1178
2,2,2-trichloroethyl
H
Me
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


23-1207
2,2,2-trichloroethyl
H
Me
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


23-1236
2,2,2-trichloroethyl
H
Me
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


23-1265
2,2,2-trichloroethyl
H
Me
N-oxide
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


23-1294
2,2,2-trichloroethyl
H
Me
N-oxide
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


23-1323
2,2,2-trichloroethyl
H
Me
N-oxide
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


23-1352
2,2,2-trichloroethyl
H
Me
N-oxide
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


23-1381
2,2,2-trichloroethyl
H
Me
N-oxide
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


23-1410
2,2,2-trichloroethyl
H
Me
N-oxide
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3











embedded image





















TABLE 24





compound














number
Q2
R1
R2
A
X2
X3
X4
Y1
Y2
Y3
Y4
Y5







24-1
2,2,2-trichloroethyl
Me
Me
N
H
H
H
F
H
heptafluoroisopropyl
H
F


24-2
2,2,2-trichloroethyl
Me
Me
N
H
H
H
F
H
nonafluoro-2-butyl
H
F


24-13
2,2,2-trichloroethyl
Me
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


24-42
2,2,2-trichloroethyl
Me
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


24-71
2,2,2-trichloroethyl
Me
Me
N
H
H
H
Br
H
heptafluoroisopropyl
H
Br


24-100
2,2,2-trichloroethyl
Me
Me
N
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


24-129
2,2,2-trichloroethyl
Me
Me
N
H
H
H
I
H
heptafluoroisopropyl
H
I


24-158
2,2,2-trichloroethyl
Me
Me
N
H
H
H
I
H
nonafluoro-2-butyl
H
I


24-376
2,2,2-trichloroethyl
Me
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
Br


24-385
2,2,2-trichloroethyl
Me
Me
N
H
H
H
F
H
heptafluoroisopropyl
H
OCF3


24-386
2,2,2-trichloroethyl
Me
Me
N
H
H
H
F
H
nonafluoro-2-butyl
H
OCF3


24-397
2,2,2-trichloroethyl
Me
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


24-426
2,2,2-trichloroethyl
Me
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


24-455
2,2,2-trichloroethyl
Me
Me
N
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


24-484
2,2,2-trichloroethyl
Me
Me
N
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


24-513
2,2,2-trichloroethyl
Me
Me
N
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


24-542
2,2,2-trichloroethyl
Me
Me
N
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


24-757
2,2,2-trichloroethyl
Me
Me
N
H
H
H
F
H
heptafluoroisopropyl
H
CF3


24-758
2,2,2-trichloroethyl
Me
Me
N
H
H
H
F
H
nonafluoro-2-butyl
H
CF3


24-764
2-iodoethyl
Me
Et
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


24-765
2-cyanoethyl
Et
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
C2F5


24-769
2,2,2-trichloroethyl
Me
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


24-771
n-propyl
Me
n-Pr
N
H
H
H
Cl
H
pentafluoroethyl
H
CF3


24-775
i-propyl
n-Pr
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


24-778
1,3-dichloro-2-propyl
Me
Me
N
H
H
H
Cl
H
pentafluoroethyl
H
CF3


24-779
1-chloro-3-fluoro-2-propyl
i-Pr
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


24-781
n-butyl
Me
i-Pr
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


24-783
i-butyl
CH2CH═CH2
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


24-784
s-butyl
Me
CH2CH═CH2
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


24-785
vinyl
Me
CN
N
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


24-789
ethyl
Me
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


24-794
2-cyanoethyl
CN
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


24-798
2,2,2-trichloroethyl
Me
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


24-799
2,2,2-tribromoethyl
Me
CH2C≡CH
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


24-800
n-propyl
CH2C≡CH
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


24-810
n-butyl
Me
NH2
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


24-812
i-butyl
NH2
Me
N
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


24-823
2-cyanoethyl
Me
C(O)OMe
N
H
H
H
Br
H
heptafluoroisopropyl
H
C2F5


24-827
2,2,2-trichloroethyl
Me
Me
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


24-829
n-propyl
C(O)OMe
Me
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


24-834
1,2-difluoro-2-propyl
Me
Me
N
H
H
H
Br
H
heptafluoroisopropyl
H
n-C3F7


24-840
4,4,4-trifluoro-n-butyl
Me
Me
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


24-841
i-butyl
Me
C(O)C(O)OMe
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


24-842
s-butyl
Me
Me
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


24-843
vinyl
C(O)C(O)OMe
Me
N
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


24-852
2-cyanoethyl
Me
C(O)OEt
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


24-856
2,2,2-trichloroethyl
Me
Me
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


24-858
n-propyl
C(O)OEt
Me
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


24-861
3-bromo-n-propyl
Me
C(O)Me
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


24-862
i-propyl
C(O)Me
Me
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


24-869
4,4,4-trifluoro-n-butyl
Me
Me
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


24-870
i-butyl
Me
C(O)C(O)OEt
N
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


24-874
phenyl
C(O)C(O)OEt
Me
N
H
H
H
Br
H
nonafluoro-2-butyl
H
i-C3F7


24-885
2,2,2-trichloroethyl
Me
Me
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


24-887
n-propyl
Me
C(O)Et
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


24-890
3-bromo-n-propyl
C(O)Et
Me
N
H
H
H
I
H
heptafluoroisopropyl
H
C2F5


24-898
4,4,4-trifluoro-n-butyl
Me
Me
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


24-899
i-butyl
Me
S(O)2Me
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


24-902
benzyl
S(O)2Me
Me
N
H
H
H
I
H
heptafluoroisopropyl
H
CF3


24-909
2-iodoethyl
Me
S(O)2Et
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


24-910
2-cyanoethyl
S(O)2Et
Me
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


24-914
2,2,2-trichloroethyl
Me
Me
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


24-915
2,2,2-tribromoethyl
Me
CH2Ph
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


24-916
n-propyl
CH2Ph
Me
N
H
H
H
I
H
nonafluoro-2-butyl
H
n-C3F7


24-920
i-propyl
CH2(3-Py)
Me
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


24-926
n-butyl
Me
CH2(3-Py)
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


24-927
4,4,4-trifluoro-n-butyl
Me
Me
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


24-929
s-butyl
CH2(3-Py—N-
Me
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3




oxide)


24-930
vinyl
Me
Me
N
H
H
H
I
H
nonafluoro-2-butyl
H
i-C3F7


24-932
phenyl
Me
CH2(3-Py—N-
N
H
H
H
I
H
nonafluoro-2-butyl
H
CF3





oxide)


24-1139
2,2,2-trichloroethyl
Me
Me
N
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


24-1168
2,2,2 trichloroethyl
Me
Me
N
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


24-1197
2,2,2-trichloroethyl
Me
Me
N
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


24-1226
2,2,2-trichloroethyl
Me
Me
N
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


24-1255
2,2,2-trichloroethyl
Me
Me
N
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


24-1284
2,2,2-trichloroethyl
Me
Me
N
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


24-1499
2,2,2-trichloroethyl
Me
Me
N-oxide
H
H
H
F
H
heptafluoroisopropyl
H
F


24-1500
2,2,2-trichloroethyl
Me
Me
N-oxide
H
H
H
F
H
nonafluoro-2-butyl
H
F


24-1511
2,2,2-trichloroethyl
Me
Me
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


24-1540
2,2,2-trichloroethyl
Me
Me
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
Cl


24-1569
2,2,2-trichloroethyl
Me
Me
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
Br


24-1598
2,2,2-trichloroethyl
Me
Me
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
Br


24-1627
2,2,2-trichloroethyl
Me
Me
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
I


24-1656
2,2,2-trichloroethyl
Me
Me
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
I


24-1875
2,2,2-trichloroethyl
Me
Me
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
I


24-1883
2,2,2-trichloroethyl
Me
Me
N-oxide
H
H
H
F
H
heptafluoroisopropyl
H
OCF3


24-1884
2,2,2-trichloroethyl
Me
Me
N-oxide
H
H
H
F
H
nonafluoro-2-butyl
H
OCF3


24-1895
2,2,2-trichloroethyl
Me
Me
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


24-1924
2,2,2-trichloroethyl
Me
Me
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


24-1953
2,2,2-trichloroethyl
Me
Me
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


24-1982
2,2,2-trichloroethyl
Me
Me
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


24-2011
2,2,2-trichloroethyl
Me
Me
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


24-2040
2,2,2-trichloroethyl
Me
Me
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


24-2255
2,2,2-trichloroethyl
Me
Me
N-oxide
H
H
H
F
H
heptafluoroisopropyl
H
CF3


24-2256
2,2,2-trichloroethyl
Me
Me
N-oxide
H
H
H
F
H
nonafluoro-2-butyl
H
CF3


24-2267
2,2,2-trichloroethyl
Me
Me
N-oxide
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


24-2296
2,2,2-trichloroethyl
Me
Me
N-oxide
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


24-2325
2,2,2-trichloroethyl
Me
Me
N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


24-2354
2,2,2-trichloroethyl
Me
Me
N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


24-2383
2,2,2-trichloroethyl
Me
Me
N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


24-2412
2,2,2-trichloroethyl
Me
Me
N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


24-2637
2,2,2-trichloroethyl
Me
Me
N-oxide
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


24-2666
2,2,2-trichloroethyl
Me
Me
N-oxide
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


24-2695
2,2,2-trichloroethyl
Me
Me
N-oxide
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


24-2724
2,2,2-trichloroethyl
Me
Me
N-oxide
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


24-2753
2,2,2-trichloroethyl
Me
Me
N-oxide
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


24-2782
2,2,2-trichloroethyl
Me
Me
N-oxide
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3











embedded image





















TABLE 25





compound














number
Q2
R1
R2
A
X2
X3
X4
Y1
Y2
Y3
Y4
Y5







25-9
2,2-dichloroethyl
H
Et
N
H
H
H
Cl
F
heptafluoroisopropyl
F
Cl


25-39
2,2,2-trifluoroethyl
H
H
N
H
H
H
Cl
Me
nonafluoro-2-butyl
Me
I


25-152
2,2-dichloroethyl
H
Et
N
H
H
H
Cl
F
heptafluoroisopropyl
F
OCF3


25-182
2,2,2-trifluoroethyl
H
H
N
H
H
H
Cl
Me
nonafluoro-2-butyl
Me
OCF3


25-287
methyl
H
H
N
H
H
H
Cl
F
heptafluoroisopropyl
H
CF3


25-288
ethyl
Me
H
N
H
H
H
Cl
H
heptafluoroisopropyl
F
CF3


25-289
2-fluoroethyl
H
Me
N
H
H
H
Cl
Cl
heptafluoroisopropyl
H
CF3


25-290
2-chloroethyl
Me
Me
N
H
H
H
Cl
H
heptafluoroisopropyl
Cl
CF3


25-291
2-bromoethyl
H
H
N
H
H
H
F
Br
heptafluoroisopropyl
H
CF3


25-292
2-iodoethyl
H
H
N
H
H
H
Cl
H
heptafluoroisopropyl
Br
CF3


25-293
2-cyanoethyl
Et
H
N
H
H
H
Cl
Cl
heptafluoroisopropyl
H
C2F5


25-294
2,2-difluoroethyl
H
H
N
H
H
H
Cl
H
heptafluoroisopropyl
I
CF3


25-295
2,2-dichloroethyl
H
Et
N
H
H
H
Cl
F
heptafluoroisopropyl
F
CF3


25-296
22,2-trifluoroethyl
H
H
N
H
H
H
Cl
F
heptafluoroisopropyl
Cl
CF3


25-299
n-propyl
H
H
N
H
H
H
Cl
Cl
pentafluoroethyl
F
CF3


25-300
3-fluoro-n-propyl
H
H
N
H
H
H
Cl
Cl
heptafluoroisopropyl
Cl
CF3


25-303
i-propyl
H
n-Pr
N
H
H
H
Cl
Br
heptafluoroisopropyl
F
CF3


25-304
1,2-difluoro-2-propyl
H
H
N
H
H
H
Cl
Br
heptafluoroisopropyl
Cl
CF3


25-307
1-chloro-3-fluoro-2-propyl
H
H
N
H
H
H
F
I
nonafluoro-2-butyl
F
CF3


25-308
3,3,3-trifluoro-n-propyl
H
H
N
H
H
H
Cl
I
nonafluoro-2-butyl
Cl
CF3


25-311
i-butyl
H
H
N
H
H
H
Cl
Me
nonafluoro-2-butyl
H
CF3


25-312
s-butyl
H
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
Me
CF3


25-313
vinyl
i-Pr
H
N
H
H
H
Cl
Et
nonafluoro-2-butyl
H
CF3


25-314
benzyl
H
H
N
H
H
H
Cl
H
nonafluoro-2-butyl
Et
CF3


25-325
2,2,2-trifluoroethyl
H
H
N
H
H
H
Cl
Me
nonafluoro-2-butyl
Me
n-C3F7


25-326
2,2,2-trichloroethyl
H
H
N
H
H
H
Cl
Me
nonafluoro-2-butyl
Et
i-C3F7


25-332
i-propyl
H
H
N
H
H
H
Cl
Et
nonafluoro-2-butyl
Me
n-C3F7


25-333
1,2-difluoro-2-propyl
H
H
N
H
H
H
Cl
Et
nonafluoro-2-butyl
Et
i-C3F7


25-339
2-chloroethyl
H
H
N
H
H
H
Br
n-Pr
heptafluoroisopropyl
Me
CF3


25-340
2-bromoethyl
H
H
N
H
H
H
Br
n-Pr
heptafluoroisopropyl
Et
CF3


25-346
2,2,2-trichloroethyl
H
H
N
H
H
H
Br
i-Pr
heptafluoroisopropyl
Me
CF3


25-347
2,2,2-tribromoethyl
H
H
N
H
H
H
Br
i-Pr
heptafluoroisopropyl
Et
CF3


25-353
1,2-difluoro-2-propyl
H
H
N
H
H
H
Br
n-Bu
heptafluoroisopropyl
Me
CF3


25-354
1,3-difluoro-2-propyl
H
H
N
H
H
H
Br
n-Bu
heptafluoroisopropyl
Et
CF3


25-360
i-butyl
H
H
N
H
H
H
Br
i-Bu
nonafluoro-2-butyl
Me
CF3


25-361
s-butyl
H
H
N
H
H
H
Br
i-Bu
nonafluoro-2-butyl
Et
CF3


25-367
2-fluoroethyl
H
H
N
H
H
H
Br
s-Bu
nonafluoro-2-butyl
Me
CF3


25-368
2-chloroethyl
H
H
N
H
H
H
Br
s-Bu
nonafluoro-2-butyl
Et
CF3


25-374
2,2,2-trifluoroethyl
H
H
N
H
H
H
Br
F
nonafluoro-2-butyl
Me
CF3


25-375
2,2,2-trifluoroethyl
H
H
N
H
H
H
Br
F
nonafluoro-2-butyl
Et
CF3


25-381
i-propyl
Et
i-Pr
N
H
H
H
Br
Cl
nonafluoro-2-butyl
Me
CF3


25-382
1,2-difluoro-2-propyl
H
H
N
H
H
H
Br
Cl
nonafluoro-2-butyl
Et
CF3


25-388
2-iodoethyl
H
H
N
H
H
H
I
Br
heptafluoroisopropyl
Me
CF3


25-389
2-cyanoethyl
H
H
N
H
H
H
I
Br
heptafluoroisopropyl
Et
CF3


25-395
n-propyl
n-Pr
Me
N
H
H
H
I
I
heptafluoroisopropyl
Me
CF3


25-396
3-fluoro-n-propyl
H
H
N
H
H
H
I
I
heptafluoroisopropyl
Et
CF3


25-402
1,3-difluoro-2-propyl
H
H
N
H
H
H
I
Me
heptafluoroisopropyl
F
C2F5


25-403
1-chloro-3-fluoro-2-propyl
H
H
N
H
H
H
I
Me
nonafluoro-2-butyl
Cl
CF3


25-406
4,4,4-trifluoro-n-butyl
H
H
N
H
H
H
I
Et
nonafluoro-2-butyl
F
CF3


25-407
i-butyl
H
H
N
H
H
H
I
Et
nonafluoro-2-butyl
Cl
CF3


25-410
benzyl
H
H
N
H
H
H
I
n-Pr
nonafluoro-2-butyl
F
CF3


25-413
ethyl
H
H
N
H
H
H
I
n-Pr
nonafluoro-2-butyl
I
N-C3F7


25-414
2-fluoroethyl
H
H
N
H
H
H
I
i-Pr
nonafluoro-2-butyl
F
i-C3F7


25-415
2-chloroethyl
H
H
N
H
H
H
I
i-Pr
nonafluoro-2-butyl
Cl
CF3


25-418
2-cyanoethyl
H
H
N
H
H
H
I
n-Bu
nonafluoro-2-butyl
F
CF3


25-419
2,2-diftuoroethyl
H
H
N
H
H
H
I
n-Bu
nonafluoro-2-butyl
Cl
CF3


25-422
2,2,2-trichloroethyl
H
H
N
H
H
H
I
i-Bu
nonafluoro-2-butyl
F
CF3


25-423
2,2,2-tribromoethyl
H
H
N
H
H
H
I
i-Bu
nonafluoro-2-butyl
Cl
CF3


25-426
3-chloro-n-propyl
i-Pr
n-Pr
N
H
H
H
1
s-Bu
nonafluoro-2-butyl
F
CF3


25-427
3-bromo-n-propyl
H
H
N
H
H
H
1
s-Bu
nonafluoro-2-butyl
Cl
CF3


25-438
2,2-dichloroethyl
H
Et
N
H
H
H
OCF3
F
heptafluoroisopropyl
F
OCF3


25-468
2,2,2-trifluoroethyl
H
H
N
H
H
H
OCF3
Me
nonafluoro-2-butyl
Me
OCF3


25-581
2,2-dichloroethyl
H
Et
N
H
H
H
OCF3
F
heptafluoroisopropyl
F
CF3


25-611
2,2,2-trifluoroethyl
H
H
N
H
H
H
OCF3
Me
nonafluoro-2-butyl
Me
CF3


25-724
2,2-dichloroethyl
H
Et
N
H
H
H
CF3
F
heptafluoroisopropyl
F
CF3


25-754
2,2,2-trifluoroethyl
H
H
N
H
H
H
CF3
Me
nonafluoro-2-butyl
Me
CF3


25-867
2,2-dichloroethyl
H
Et
N-oxide
H
H
H
Cl
F
heptafluoroisopropyl
F
Cl


25-897
2,2,2-trifluoroethyl
H
H
N-oxide
H
H
H
Cl
Me
nonafluoro-2-butyl
Me
I


25-1010
2,2-dichloroethyl
H
Et
N-oxide
H
H
H
Cl
F
heptafluoroisopropyl
F
OCF3


25-1040
2,2,2-trifluoroethyl
H
H
N-oxide
H
H
H
Cl
Me
nonafluoro-2-butyl
Me
OCF3


25-1155
2,2,2-trichloroethyl
H
H
N-oxide
H
H
H
Cl
F
heptafluoroisopropyl
Br
CF3


25-1168
4,4,4-trifluoro-n-butyl
H
H
N-oxide
H
H
H
Cl
I
nonafluoro-2-butyl
I
CF3


25-1184
2,2,2-trichloroethyl
H
H
N-oxide
H
H
H
Cl
Me
nonafluoro-2-butyl
Et
i-C3F7


25-1233
2,2,2-trichloroethyl
H
H
N-oxide
H
H
H
Br
F
nonafluoro-2-butyl
Et
CF3


25-1264
4,4,4-trrfluoro-n-butyl
H
H
N-oxide
H
H
H
I
Et
nonafluoro-2-butyl
F
CF3


25-1296
2,2-dichloroethyl
H
Et
N-oxide
H
H
H
OCF3
F
heptafluoroisopropyl
F
OCF3


25-1326
2,2,2-trifluoroethyl
H
H
N-oxide
H
H
H
OCF3
Me
nonafluoro-2-butyl
Me
OCF3


25-1439
2,2-dichloroethyl
H
Et
N-oxide
H
H
H
OCF3
F
heptafluoroisopropyl
F
CF3


25-1469
2,2,2-trifluoroethyl
H
H
N-oxide
H
H
H
OCF3
Me
nonafluoro-2-butyl
Me
CF3


25-1582
2,2-dichloroethyl
H
Et
N-oxide
H
H
H
CF3
F
heptafluoroisopropyl
F
CF3


25-1612
2,2,2-trifluoroethyl
H
H
N-oxide
H
H
H
CF3
Me
nonafluoro-2-butyl
Me
CF3











embedded image


















TABLE 26





compound











number
Q1
R1
R2
X3
Y1
Y2
Y3
Y4
Y5







26-1
phenyl
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


26-4
4-fluorophenyl
H
H
Cl
Cl
H
heptafluoroisopropyl
H
OCF3


26-12
3-iodophenyl
H
H
H
Cl
H
pentafluoroethyl
H
OCF3


26-13
4-iodophenyl
H
H
H
Cl
H
pentafluoroethyl
H
OCF3


26-16
(4-trifluoromethyl)phenyl
H
H
H
Cl
H
heptafluoroisopropyl
H
OC2F5


26-17
2-nitrophenyl
H
H
H
F
H
heptafluoroisopropyl
H
OCF3


26-20
2-cyanophenyl
H
H
H
Cl
H
pentafluoroethyl
H
OC2F5


26-21
3-cyanophenyl
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


26-22
4-cyanophenyl
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


26-28
4-bromo-2-chlorophenyl
H
H
H
Cl
H
heptafluoroisopropyl
H
OC2F5


26-36
2-fluoropyridin-3-yl
H
H
H
Cl
H
pentafluoroethyl
H
OCF3


26-37
2-chloropyridin-3-yl
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


26-41
2-nitropyridin-3-yl
H
H
H
Cl
H
heptafluoroisopropyl
H
OC2F5


26-50
5-fluoropyridin-3-yl
H
H
H
Cl
H
heptafluoroisopropyl
H
OC2F5


26-55
5-nitropyridin-3-yl
H
H
H
Cl
H
pentafluoroethyl
H
OCF3


26-59
4-bromopyridin-3-yl
H
H
H
Cl
H
heptafluoroisopropyl
H
OC2F5


26-60
4-iodopyridin-3-yl
H
H
H
Cl
H
heptafluoroisopropyl
H
OC2F5


26-78
4-cyanopyridin-2-yl
H
H
H
Cl
H
pentafluoroethyl
H
OCF3


26-79
phenyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


26-95
2-nitrophenyl
H
H
H
F
H
nonafluoro-2-butyl
H
OCF3


26-99
3-cyanophenyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


26-100
4-cyanophenyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


26-105
2-chloro-4,5-difluorophenyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
OC2F5


26-115
2-chloropyridin-3-yl
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


26-121
6-fluoropyridin-3-yl
H
H
H
Cl
H
nonafluoro-2-butyl
H
OC2F5


26-130
5-bromopyridin-3-yl
H
H
H
Cl
H
nonafluoro-2-butyl
H
OC2F5


26-131
5-iodopyridin-3-yl
H
H
H
Cl
H
nonafluoro-2-butyl
H
OC2F5


26-139
4-(trifluoromethyl)pyridin-3-yl
H
H
H
Cl
H
nonafluoro-2-butyl
H
OC2F5


26-140
4-nitropyridin-3-yl
H
H
H
Cl
H
nonafluoro-2-butyl
H
OC2F5


26-157
phenyl
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


26-158
2-fluorophenyl
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


26-177
3-cyanophenyl
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


26-178
4-cyanophenyl
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


26-193
2-chloropyridin-3-yl
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


26-235
phenyl
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


26-236
2-fluorophenyl
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


26-255
3-cyanophenyl
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


26-256
4-cyanophenyl
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


26-271
2-chloropyridin-3-yl
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


26-313
phenyl
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


26-314
2-fluorophenyl
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


26-333
3-cyanophenyl
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


26-334
4-cyanophenyl
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


26-349
2-chloropyridin-3-yl
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


26-391
phenyl
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


26-392
2-fluorophenyl
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


26-411
3-cyanophenyl
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


26-412
4-cyanophenyl
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


26-427
2-chloropyridin-3-yl
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


26-469
phenyl
H
H
H
F
H
heptafluoroisopropyl
H
CF3


26-470
phenyl
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


26-471
2-fluorophenyl
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


26-481
3-iodophenyl
H
H
H
Cl
H
pentafluoroethyl
H
CF3


26-482
4-iodophenyl
H
H
H
Cl
H
pentafluoroethyl
H
CF3


26-489
2-cyanophenyl
H
H
H
Cl
H
pentafluoroethyl
H
C2F5


26-490
3-cyanophenyl
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


26-491
4-cyanophenyl
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


26-494
2,4-dichlorophenyl
H
H
H
Cl
H
heptafluoroisopropyl
H
C2F5


26-498
2-bromo-4-chlorophenyl
H
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


26-505
2-fluoropyridin-3-yl
H
H
H
Cl
H
pentafluoroethyl
H
CF3


26-506
2-chloropyridin-3-yl
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


26-510
2-nitropyridin-3-yl
H
H
Cl
Cl
H
heptafluoroisopropyl
H
CF3


26-519
5-fluoropyridin-3-yl
H
H
H
Cl
H
heptafluoroisopropyl
H
C2F5


26-521
5-bromopyridin-3-yl
H
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


26-522
5-iodopyridin-3-yl
H
H
H
Cl
H
heptafluoroisopropyl
H
i-C3F7


26-524
5-nitropyridin-3-yl
H
H
H
Cl
H
pentafluoroethyl
H
CF3


26-526
4-fluoropyridin-3-yl
H
H
H
Cl
H
pentafluoroethyl
H
CF3


26-528
4-bromopyridin-3-yl
H
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


26-529
4-iodopyridin-3-yl
H
H
H
Cl
H
heptafluoroisopropyl
H
i-C3F7


26-548
phenyl
H
H
H
F
H
nonafluoro-2-butyl
H
CF3


26-549
phenyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


26-550
2-fluorophenyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


26-562
(2-trifluoromethyl)phenyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


26-569
3-cyanophenyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


26-570
4-cyanophenyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


26-579
2-chloro-4-nitrophenyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


26-585
2-chloropyridin-3-yl
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


26-598
5-fluoropyridin-3-yl
H
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


26-600
5-bromopyridin-3-yl
H
H
H
Cl
H
nonafluoro-2-butyl
H
n-C3F7


26-601
5-iodopyridin-3-yl
H
H
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


26-605
4-fluoropyridin-3-yl
H
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


26-609
4-(trifluoromethyl)pyridin-3-yl
H
H
H
Cl
H
nonafluoro-2-butyl
H
n-C3F7


26-610
4-nitropyridin-3-yl
H
H
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


26-626
4-cyanopyridin-2-yl
H
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


26-627
phenyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-628
2-fluorophenyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-629
3-fluorophenyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-630
4-fluorophenyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-631
2-chlorophenyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-632
3-chlorophenyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-633
4-chlorophenyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-634
2-bromophenyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-635
3-bromophenyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-636
4-bromophenyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-637
2-iodophenyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-638
3-iodophenyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-639
4-iodophenyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-640
(2-trifluoromethyl)phenyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-641
(3-trifluoromethyl)phenyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-642
(4-trifluoromethyl)phenyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-643
2-nitrophenyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-644
3-nitrophenyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-645
4-nitrophenyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-646
2-cyanophenyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-647
3-cyanophenyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-648
4-cyanophenyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-649
2,6-difluorophenyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-650
3,4-dichlorophenyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-651
2,4-dichlorophenyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-652
2-chloro-4-fluorophenyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-653
2-chloro-4,5-difluorophenyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-654
4-bromo-2-chlorophenyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-655
2-bromo-4-chlorophenyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-656
2-bromo-4-fluorophenyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-657
2-chloro-4-nitrophenyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-658
3,5-dicyanophenyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-659
4-cyano-2-fluorophenyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-660
2-chloro-4-cyanophenyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-661
pyridin-3-yl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-662
2-fluoropyridin-3-yl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-663
2-chloropyridin-3-yl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-664
2-bromopyridin-3-yl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-665
2-iodopyridin-3-yl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-666
2-(trifluoromethyl)pyridin-3-yl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-667
2-nitropyridin-3-yl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-668
2-cyanopyridin-3-yl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-669
6-fluoropyridin-3-yl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-670
6-chloropyridin-3-yl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-671
6-bromopyridin-3-yl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-672
6-iodopyridin-3-yl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-673
6-(trifluoromethyl)pyridin-3-yl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-674
6-nitropyridin-3-yl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-675
6-cyanopyridin-3-yl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-676
5-fluoropyridin-3-yl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-677
5-chloropyridin-3-yl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-678
5-bromopyridin-3-yl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-679
5-iodopyridin-3-yl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-680
5-(trifluoromethyl)pyridin-3-yl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-681
5-nitropyridin-3-yl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-682
5-cyanopyridin-3-yl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-683
4-fluoropyridin-3-yl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-684
4-chloropyridin-3-yl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-685
4-bromopyridin-3-yl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-686
4-iodopyridin-3-yl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-687
4-(trifluoromethyl)pyridin-3-yl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-688
4-nitropyridin-3-yl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-689
4-cyanopyridin-3-yl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-690
2,6-dichloropyridin-3-yl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-691
pyridin-3-yl N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-692
pyridin-4-yl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-693
2-chloropyridin-4-yl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-694
3-bromopyridin-4-yl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-695
3,5-dichloropyridin-4-yl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-696
3-(trifluoromethyl)pyridin-4-yl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-697
2,6-dicyanopyridin-4-yl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-698
pyridin-4-yl N-oxide
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-699
pyridin-2-yl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-700
3-chloropyridin-2-yl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-701
4-bromopyridin-2-yl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-702
5-iodopyridin-2-yl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-703
6-chloropyridin-2-yl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-704
4-cyanopyridin-2-yl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


26-705
phenyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-706
2-fluorophenyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-707
3-fluorophenyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-708
4-fluorophenyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-709
2-chlorophenyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-710
3-chlorophenyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-711
4-chlorophenyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-712
2-bromophenyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-713
3-bromophenyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-714
4-bromophenyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-715
2-iodophenyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-716
3-iodophenyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-717
4-iodophenyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-718
(2-trifluoromethyl)phenyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-719
(3-trifluoromethyl)phenyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-720
(4-trifluoromethyl)phenyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-721
2-nitrophenyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-722
3-nitrophenyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-723
4-nitrophenyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-724
2-cyanophenyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-725
3-cyanophenyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-726
4-cyanophenyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-727
2,6-difluorophenyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-728
3,4-dichlorophenyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-729
2,4-dichlorophenyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-730
2-chloro-4-fluorophenyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-731
2-chloro-4,5-difluorophenyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-732
4-bromo-2-chlorophenyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-733
2-bromo-4-chlorophenyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-734
2-bromo-4-fluorophenyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-735
2-chloro-4-nitrophenyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-736
3,5-dicyanophenyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-737
4-cyano-2-fluorophenyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-738
2-chloro-4-cyanophenyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-739
pyridin-3-yl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-740
2-fluoropyridin-3-yl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-741
2-chloropyridin-3-yl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-742
2-bromopyridin-3-yl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-743
2-iodopyridin-3-yl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-744
2-(trifluoromethyl)pyridin-3-yl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-745
2-nitropyridin-3-yl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-746
2-cyanopyridin-3-yl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-747
6-fluoropyridin-3-yl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-748
6-chloropyridin-3-yl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-749
6-bromopyridin-3-yl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-750
6-iodopyridin-3-yl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-751
6-(trifluoromethyl)pyridin-3-yl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-752
6-nitropyridin-3-yl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-753
6-cyanopyridin-3-yl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-754
5-fluoropyridin-3-yl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-755
5-chloropyridin-3-yl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-756
5-bromopyridin-3-yl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-757
5-iodopyridin-3-yl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-758
5-(trifluoromethyl)pyridin-3-yl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-759
5-nitropyridin-3-yl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-760
5-cyanopyridin-3-yl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-761
4-fluoropyridin-3-yl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-762
4-chloropyridin-3-yl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-763
4-bromopyridin-3-yl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-764
4-iodopyridin-3-yl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-765
4-(trifluoromethyl)pyridin-3-yl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-766
4-nitropyridin-3-yl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-767
4-cyanopyridin-3-yl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-768
2,6-dichloropyridin-3-yl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-769
pyridin-3-yl N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-770
pyridin-4-yl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-771
2-chloropyridin-4-yl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-772
3-bromopyridin-4-yl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-773
3,5-dichloropyridin-4-yl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-774
3-(trifluoromethyl)pyridin-4-yl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-775
2,6-dicyanopyridin-4-yl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-776
pyridin-4-yl N-oxide
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-777
pyridin-2-yl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-778
3-chloropyridin-2-yl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-779
4-bromopyridin-2-yl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-780
5-iodopyridin-2-yl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-781
6-chloropyridin-2-yl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-782
4-cyanopyridin-2-yl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


26-783
phenyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-784
2-fluorophenyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-785
3-fluorophenyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-786
4-fluorophenyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-787
2-chlorophenyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-788
3-chlorophenyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-789
4-chlorophenyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-790
2-bromophenyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-791
3-bromophenyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-792
4-bromophenyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-793
2-iodophenyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-794
3-iodophenyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-795
4-iodophenyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-796
(2-trifluoromethyl)phenyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-797
(3-trifluoromethyl)phenyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-798
(4-trifluoromethyl)phenyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-799
2-nitrophenyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-800
3-nitrophenyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-801
4-nitrophenyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-802
2-cyanophenyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-803
3-cyanophenyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-804
4-cyanophenyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-805
2,6-difluorophenyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-806
3,4-dichlorophenyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-807
2,4-dichlorophenyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-808
2-chloro-4-fluorophenyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-809
2-chloro-4,5-difluorophenyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-810
4-bromo-2-chlorophenyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-811
2-bromo-4-chlorophenyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-812
2-bromo-4-fluorophenyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-813
2-chloro-4-nitrophenyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-814
3,5-dicyanophenyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-815
4-cyano-2-fluorophenyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-816
2-chloro-4-cyanophenyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-817
pyridin-3-yl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-818
2-fluoropyridin-3-yl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-819
2-chloropyridin-3-yl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-820
2-bromopyridin-3-yl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-821
2-iodopyridin-3-yl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-822
2-(trifluoromethyl)pyridin-3-yl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-823
2-nitropyridin-3-yl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-824
2-cyanopyridin-3-yl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-825
6-fluoropyridin-3-yl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-826
6-chloropyridin-3-yl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-827
6-bromopyridin-3-yl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-828
6-iodopyridin-3-yl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-829
6-(trifluoromethyl)pyridin-3-yl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-830
6-nitropyridin-3-yl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-831
6-cyanopyridin-3-yl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-832
5-fluoropyridin-3-yl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-833
5-chloropyridin-3-yl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-834
5-bromopyridin-3-yl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-835
5-iodopyridin-3-yl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-836
5-(trifluoromethyl)pyridin-3-yl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-837
5-nitropyridin-3-yl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-838
5-cyanopyridin-3-yl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-839
4-fluoropyridin-3-yl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-840
4-chloropyridin-3-yl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-841
4-bromopyridin-3-yl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-842
4-iodopyridin-3-yl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-843
4-(trifluoromethyl)pyridin-3-yl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-844
4-nitropyridin-3-yl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-845
4-cyanopyridin-3-yl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-846
2,6-dichloropyridin-3-yl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-847
pyridin-3-yl N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-848
pyridin-4-yl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-849
2-chloropyridin-4-yl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-850
3-bromopyridin-4-yl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-851
3,5-dichloropyridin-4-yl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-852
3-(trifluoromethyl)pyridin-4-yl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-853
2,6-dicyanopyridin-4-yl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-854
pyridin-4-yl N-oxide
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-855
pyridin-2-yl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-856
3-chloropyridin-2-yl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-857
4-bromopyridin-2-yl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-858
5-iodopyridin-2-yl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-859
6-chloropyridin-2-yl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-860
4-cyanopyridin-2-yl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


26-861
phenyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-862
2-fluorophenyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-863
3-fluorophenyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-864
4-fluorophenyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-865
2-chlorophenyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-866
3-chlorophenyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-867
4-chlorophenyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-868
2-bromophenyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-869
3-bromophenyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-870
4-bromophenyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-871
2-iodophenyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-872
3-iodophenyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-873
4-iodophenyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-874
(2-trifluoromethyl)phenyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-875
(3-trifluoromethyl)phenyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-876
(4-trifluoromethyl)phenyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-877
2-nitrophenyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-878
3-nitrophenyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-879
4-nitrophenyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-880
2-cyanophenyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-881
3-cyanophenyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-882
4-cyanophenyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-883
2,6-difluorophenyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-884
3,4-dichlorophenyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-885
2,4-dichlorophenyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-886
2-chloro-4-fluorophenyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-887
2-chloro-4,5-difluorophenyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-888
4-bromo-2-chlorophenyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-889
2-bromo-4-chlorophenyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-890
2-bromo-4-fluorophenyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-891
2-chloro-4-nitrophenyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-892
3,5-dicyanophenyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-893
4-cyano-2-fluorophenyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-894
2-chloro-4-cyanophenyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-895
pyridin-3-yl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-896
2-fluoropyridin-3-yl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-897
2-chloropyridin-3-yl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-898
2-bromopyridin-3-yl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-899
2-iodopyridin-3-yl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-900
2-(trifluoromethyl)pyridin-3-yl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-901
2-nitropyridin-3-yl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-902
2-cyanopyridin-3-yl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-903
6-fluoropyridin-3-yl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-904
6-chloropyridin-3-yl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-905
6-bromopyridin-3-yl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-906
6-iodopyridin-3-yl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-907
6-(trifluoromethyl)pyridin-3-yl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-908
6-nitropyridin-3-yl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-909
6-cyanopyridin-3-yl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-910
5-fluoropyridin-3-yl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-911
5-chloropyridin-3-yl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-912
5-bromopyridin-3-yl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-913
5-iodopyridin-3-yl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-914
5-(trifluoromethyl)pyridin-3-yl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-915
5-nitropyridin-3-yl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-916
5-cyanopyridin-3-yl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-917
4-fluoropyridin-3-yl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-918
4-chloropyridin-3-yl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-919
4-bromopyridin-3-yl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-920
4-iodopyridin-3-yl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-921
4-(trifluoromethyl)pyridin-3-yl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-922
4-nitropyridin-3-yl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-923
4-cyanopyridin-3-yl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-924
2,6-dichloropyridin-3-yl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-925
pyridin-3-yl N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-926
pyridin-4-yl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-927
2-chloropyridin-4-yl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-928
3-bromopyridin-4-yl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-929
3,5-dichloropyridin-4-yl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-930
3-(trifluoromethyl)pyridin-4-yl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-931
2,6-dichloropyridin-4-yl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-932
pyridin-4-yl N-oxide
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-933
pyridin-2-yl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-934
3-chloropyridin-2-yl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-935
4-bromopyridin-2-yl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-936
5-iodopyridin-2-yl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-937
6-chloropyridin-2-yl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-938
4-cyanopyridin-2-yl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


26-939
phenyl
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


26-946
2-bromophenyl
H
H
H
OCF3
H
heptafluoroisopropyl
H
OC2F5


26-950
3-iodophenyl
H
H
H
OCF3
H
pentafluoroethyl
H
OCF3


26-951
4-iodophenyl
H
H
H
OCF3
H
pentafluoroethyl
H
OCF3


26-954
3-cyanophenyl
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


26-955
4-cyanophenyl
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


26-960
2-chloro-4,5-difluorophenyl
H
H
H
OC2F5
H
heptafluoroisopropyl
H
OC2F5


26-963
2-bromo-4-fluorophenyl
H
H
H
OC2F5
H
heptafluoroisopropyl
H
OCF3


26-964
2-chloro-4-nitrophenyl
H
H
Cl
OCF3
H
heptafluoroisopropyl
H
OCF3


26-969
2-fluoropyridin-3-yl
H
H
H
OCF3
H
pentafluoroethyl
H
OCF3


26-970
2-chloropyridin-3-yl
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


26-979
5-cyanopyridin-3-yl
H
H
H
OC2F5
H
heptafluoroisopropyl
H
OC2F5


26-981
4-cyanopyridin-3-yl
H
H
H
OCF3
H
heptafluoroisopropyl
H
OC2F5


26-994
4-cyanopyridin-2-yl
H
H
H
OCF3
H
pentafluoroethyl
H
OCF3


26-995
phenyl
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


26-1002
2-bromophenyl
H
H
H
OC2F5
H
nonafluoro-2-butyl
H
OCF3


26-1008
(2-trifluoromethyl)phenyl
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OC2F5


26-1010
3-cyanophenyl
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


26-1011
4-cyanophenyl
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


26-1017
4-bromo-2-chlorophenyl
H
H
H
OC2F5
H
nonafluoro-2-butyl
H
OC2F5


26-1026
2-chloropyridin-3-yl
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


26-1033
6-cyanopyridin-3-yl
H
H
H
OC2F5
H
nonafluoro-2-butyl
H
OCF3


26-1035
5-cyanopyridin-3-yl
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OC2F5


26-1037
4-cyanopyridin-3-yl
H
H
H
OC2F5
H
nonafluoro-2-butyl
H
OC2F5


26-1051
phenyl
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


26-1058
2-bromophenyl
H
H
H
CF3
H
heptafluoroisopropyl
H
OC2F5


26-1062
3-iodophenyl
H
H
H
CF3
H
pentafluoroethyl
H
OCF3


26-1063
4-iodophenyl
H
H
H
CF3
H
pentafluoroethyl
H
OCF3


26-1064
(2-trifluoromethyl)phenyl
H
H
H
C2F5
H
heptafluoroisopropyl
H
OC2F5


26-1065
3-nitrophenyl
H
H
H
C2F5
H
heptafluoroisopropyl
H
OCF3


26-1066
3-cyanophenyl
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


26-1067
4-cyanophenyl
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


26-1074
2-bromo-4-chlorophenyl
H
H
H
n-C3F7
H
heptafluoroisopropyl
H
OCF3


26-1078
4-cyano-2-fluorophenyl
H
H
H
i-C3F7
H
heptafluoroisopropyl
H
OCF3


26-1081
2-fluoropyridin-3-yl
H
H
H
CF3
H
pentafluoroethyl
H
OCF3


26-1082
2-chloropyridin-3-yl
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


26-1089
6-cyanopyridin-3-yl
H
H
H
n-C3F7
H
heptafluoroisopropyl
H
OC2F5


26-1091
5-cyanopyridin-3-yl
H
H
H
i-C3F7
H
heptafluoroisopropyl
H
OC2F5


26-1106
4-cyanopyridin-2-yl
H
H
H
CF3
H
pentafluoroethyl
H
OCF3


26-1107
phenyl
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


26-1118
3-iodophenyl
H
H
H
CF3
H
nonafluoro-2-butyl
H
OC2F5


26-1121
3-nitrophenyl
H
H
H
C2F5
H
nonafluoro-2-butyl
H
OCF3


26-1122
3-cyanophenyl
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


26-1123
4-cyanophenyl
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


26-1129
4-bromo-2-chlorophenyl
H
H
H
i-C3F7
H
nonafluoro-2-butyl
H
OCF3


26-1132
2-chloro-4-nitrophenyl
H
H
H
n-C3F7
H
nonafluoro-2-butyl
H
OCF3


26-1138
2-chloropyridin-3-yl
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


26-1147
5-cyanopyridin-3-yl
H
H
H
C2F5
H
nonafluoro-2-butyl
H
OC2F5


26-1149
4-cyanopyridin-3-yl
H
H
H
n-C3F7
H
nonafluoro-2-butyl
H
OC2F5


26-1160
5-iodopyridin-2-yl
H
H
H
i-C3F7
H
nonafluoro-2-butyl
H
OC2F5


26-1163
phenyl
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


26-1174
3-iodophenyl
H
H
H
CF3
H
pentafluoroethyl
H
CF3


26-1175
4-iodophenyl
H
H
H
CF3
H
pentafluoroethyl
H
CF3


26-1177
(3-trifluoromethyl)phenyl
H
H
H
C2F5
H
heptafluoroisopropyl
H
CF3


26-1183
3-cyanophenyl
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


26-1184
4-cyanophenyl
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


26-1190
4-bromo-2-chlorophenyl
H
H
H
n-C3F7
H
heptafluoroisopropyl
H
CF3


26-1195
4-cyano-2-fluorophenyl
H
H
H
i-C3F7
H
heptafluoroisopropyl
H
CF3


26-1198
2-fluoropyridin-3-yl
H
H
H
CF3
H
pentafluoroethyl
H
CF3


26-1199
2-chloropyridin-3-yl
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


26-1200
2-bromopyridin-3-yl
H
H
H
C2F5
H
heptafluoroisopropyl
H
C2F5


26-1203
2-nitropyridin-3-yl
H
H
Cl
CF3
H
heptafluoroisopropyl
H
CF3


26-1211
6-cyanopyridin-3-yl
H
H
H
C2F5
H
heptafluoroisopropyl
H
n-C3F7


26-1215
4-cyanopyridin-3-yl
H
H
H
C2F5
H
heptafluoroisopropyl
H
i-C3F7


26-1230
4-cyanopyridin-2-yl
H
H
H
CF3
H
pentafluoroethyl
H
CF3


26-1231
phenyl
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


26-1243
4-iodophenyl
H
H
H
C2F5
H
nonafluoro-2-butyl
H
CF3


26-1251
3-cyanophenyl
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


26-1252
4-cyanophenyl
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


26-1258
4-bromo-2-chlorophenyl
H
H
H
n-C3F7
H
nonafluoro-2-butyl
H
CF3


26-1263
4-cyano-2-fluorophenyl
H
H
H
i-C3F7
H
nonafluoro-2-butyl
H
CF3


26-1267
2-chloropyridin-3-yl
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


26-1268
2-bromopyridin-3-yl
H
H
H
C2F5
H
nonafluoro-2-butyl
H
C2F5


26-1279
6-cyanopyridin-3-yl
H
H
H
C2F5
H
nonafluoro-2-butyl
H
n-C3F7


26-1283
4-cyanopyridin-3-yl
H
H
H
C2F5
H
nonafluoro-2-butyl
H
i-C3F7











embedded image


















TABLE 27





compound











number
Q1
R1
R2
X3
Y1
Y2
Y3
Y4
Y5







27-1
phenyl
Me
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


27-21
3-cyanophenyl
Me
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


27-22
4-cyanophenyl
Me
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


27-37
2-chloropyridin-3-yl
Me
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


27-79
phenyl
Me
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


27-99
3-cyanophenyl
Me
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


27-100
4-cyanophenyl
Me
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


27-115
2-chloropyridin-3-yl
Me
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


27-157
phenyl
Me
H
H
Br
H
heptafluoroisopropyl
H
OCF3


27-177
3-cyanophenyl
Me
H
H
Br
H
heptafluoroisopropyl
H
OCF3


27-178
4-cyanophenyl
Me
H
H
Br
H
heptafluoroisopropyl
H
OCF3


27-193
2-chloropyridin-3-yl
Me
H
H
Br
H
heptafluoroisopropyl
H
OCF3


27-235
phenyl
Me
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


27-255
3-cyanophenyl
Me
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


27-256
4-cyanophenyl
Me
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


27-271
2-chloropyridin-3-yl
Me
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


27-313
phenyl
Me
H
H
I
H
heptafluoroisopropyl
H
OCF3


27-333
3-cyanophenyl
Me
H
H
I
H
heptafluoroisopropyl
H
OCF3


27-334
4-cyanophenyl
Me
H
H
I
H
heptafluoroisopropyl
H
OCF3


27-349
2-chloropyridin-3-yl
Me
H
H
I
H
heptafluoroisopropyl
H
OCF3


27-391
phenyl
Me
H
H
I
H
nonafluoro-2-butyl
H
OCF3


27-411
3-cyanophenyl
Me
H
H
I
H
nonafluoro-2-butyl
H
OCF3


27-412
4-cyanophenyl
Me
H
H
I
H
nonafluoro-2-butyl
H
OCF3


27-427
2-chloropyridin-3-yl
Me
H
H
I
H
nonafluoro-2-butyl
H
OCF3


27-469
phenyl
Me
H
H
F
H
heptafluoroisopropyl
H
CF3


27-470
phenyl
Me
H
H
Cl
H
heptafluoroisopropyl
H
CF3


27-484
(3-trifluoromethyl)phenyl
Et
H
H
Cl
H
heptafluoroisopropyl
H
CF3


27-489
2-cyanophenyl
Me
H
H
Cl
H
pentafluoroethyl
H
C2F5


27-490
3-cyanophenyl
Me
H
H
Cl
H
heptafluoroisopropyl
H
CF3


27-491
4-cyanophenyl
Me
H
H
Cl
H
heptafluoroisopropyl
H
CF3


27-494
2,4-dichlorophenyl
Me
H
H
Cl
H
heptafluoroisopropyl
H
C2F5


27-495
2-chloro-4-fluorophenyl
n-Pr
H
H
Cl
H
heptafluoroisopropyl
H
CF3


27-498
2-bromo-4-chlorophenyl
Me
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


27-506
2-chloropyridin-3-yl
Me
H
H
Cl
H
heptafluoroisopropyl
H
CF3


27-510
2-nitropyridin-3-yl
Me
H
Cl
Cl
H
heptafluoroisopropyl
H
CF3


27-512
6-fluoropyridin-3-yl
i-Pr
H
H
Cl
H
heptafluoroisopropyl
H
CF3


27-519
5-fluoropyridin-3-yl
Me
H
H
Cl
H
heptafluoroisopropyl
H
C2F5


27-521
5-bromopyridin-3-yl
Me
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


27-522
5-iodopyridin-3-yl
Me
H
H
Cl
H
heptafluoroisopropyl
H
i-C3F7


27-528
4-bromopyridin-3-yl
CH2CH═CH2
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


27-529
4-iodopyridin-3-yl
Me
H
H
Cl
H
heptafluoroisopropyl
H
i-C3F7


27-535
pyridin-4-yl
CN
H
H
Cl
H
heptafluoroisopropyl
H
CF3


27-548
phenyl
Me
H
H
F
H
nonafluoro-2-butyl
H
CF3


27-549
phenyl
Me
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


27-557
3-bromophenyl
CH2C≡CH
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


27-562
(2-trifluoromethyl)phenyl
Me
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


27-564
(4-trifluoromethyl)phenyl
NH2
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


27-569
3-cyanophenyl
Me
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


27-570
4-cyanophenyl
Me
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


27-577
2-bromo-4-chlorophenyl
C(O)OMe
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


27-579
2-chloro-4-nitrophenyl
Me
H
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


27-585
2-chloropyridin-3-yl
Me
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


27-598
5-fluoropyridin-3-yl
C(O)OEt
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


27-600
5-bromopyridin-3-yl
Me
H
H
Cl
H
nonafluoro-2-butyl
H
n-C3F7


27-601
5-iodopyridin-3-yl
Me
H
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


27-605
4-fluoropyridin-3-yl
Me
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


27-607
4-bromopyridin-3-yl
C(O)C(O)Me
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


27-609
4-(trifluoromethyl)pyridin-3-yl
Me
H
H
Cl
H
nonafluoro-2-butyl
H
n-C3F7


27-610
4-nitropyridin-3-yl
C(O)C(O)Et
H
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


27-624
5-iodopyridin-2-yl
C(O)Me
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


27-626
4-cyanopyridin-2-yl
C(O)Et
H
H
Cl
H
nonafluoro-2-butyl
H
C2F5


27-627
phenyl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-628
2-fluorophenyl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-629
3-fluorophenyl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-630
4-fluorophenyl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-631
2-chlorophenyl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-632
3-chlorophenyl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-633
4-chlorophenyl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-634
2-bromophenyl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-635
3-bromophenyl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-636
4-bromophenyl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-637
2-iodophenyl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-638
3-iodophenyl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-639
4-iodophenyl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-640
(2-trifluoromethyl)phenyl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-641
(3-trifluoromethyl)phenyl
S(O)2Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-642
(4-trifluoromethyl)phenyl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-643
2-nitrophenyl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-644
3-nitrophenyl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-645
4-nitrophenyl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-646
2-cyanophenyl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-647
3-cyanophenyl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-648
4-cyanophenyl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-649
2,6-difluorophenyl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-650
3,4-dichlorophenyl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-651
2,4-dichlorophenyl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-652
2-chloro-4-fluorophenyl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-653
2-chloro-4,5-difluorophenyl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-654
4-bromo-2-chlorophenyl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-655
2-bromo-4-chlorophenyl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-656
2-bromo-4-fluorophenyl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-657
2-chloro-4-nitrophenyl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-658
3,5-dicyanophenyl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-659
4-cyano-2-fluorophenyl
S(O)2Et
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-660
2-chloro-4-cyanophenyl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-661
pyridin-3-yl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-662
2-fluoropyridin-3-yl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-663
2-chloropyridin-3-yl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-664
2-bromopyridin-3-yl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-665
2-iodopyridin-3-yl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-666
2-(trifluoromethyl)pyridin-3-yl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-667
2-nitropyridin-3-yl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-668
2-cyanopyridin-3-yl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-669
6-fluoropyridin-3-yl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-670
6-chloropyridin-3-yl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-671
6-bromopyridin-3-yl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-672
6-iodopyridin-3-yl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-673
6-(trifluoromethyl)pyridin-3-yl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-674
6-nitropyridin-3-yl
CH2Ph
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-675
6-cyanopyridin-3-yl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-676
5-fluoropyridin-3-yl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-677
5-chloropyridin-3-yl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-678
5-bromopyridin-3-yl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-679
5-iodopyridin-3-yl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-680
5-(trifluoromethyl)pyridin-3-yl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-681
5-nitropyridin-3-yl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-682
5-cyanopyridin-3-yl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-683
4-fluoropyridin-3-yl
CH2(3-Py)
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-684
4-chloropyridin-3-yl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-685
4-bromopyridin-3-yl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-686
4-iodopyridin-3-yl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-687
4-(trifluoromethyl)pyridin-3-yl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-688
4-nitropyridin-3-yl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-689
4-cyanopyridin-3-yl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-690
2,6-dichloropyridin-3-yl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-691
pyridin-3-yl N-oxide
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-692
pyridin-4-yl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-693
2-chloropyridin-4-yl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-694
3-bromopyridin-4-yl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-695
3,5-dichloropyridin-4-yl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-696
3-(trifluoromethyl)pyridin-4-yl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-697
2,6-dicyanopyridin-4-yl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-698
pyridin-4-yl N-oxide
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-699
pyridin-2-yl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-700
3-chloropyridin-2-yl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-701
4-bromopyridin-2-yl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-702
5-iodopyridin-2-yl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-703
6-chloropyridin-2-yl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


27-704
4-cyanopyridin-2-yl
CH2(3-Py—N-
H
H
Br
H
heptafluoroisopropyl
H
CF3




oxide)


27-705
phenyl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-706
2-fluorophenyl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-707
3-fluorophenyl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-708
4-fluorophenyl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-709
2-chlorophenyl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-710
3-chlorophenyl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-711
4-chlorophenyl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-712
2-bromophenyl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-713
3-bromophenyl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-714
4-bromophenyl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-715
2-iodophenyl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-716
3-iodophenyl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-717
4-iodophenyl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-718
(2-trifluoromethyl)phenyl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-719
(3-trifluoromethyl)phenyl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-720
(4-trifluoromethyl)phenyl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-721
2-nitrophenyl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-722
3-nitrophenyl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-723
4-nitrophenyl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-724
2-cyanophenyl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-725
3-cyanophenyl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-726
4-cyanophenyl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-727
2,6-difluorophenyl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-728
3,4-dichlorophenyl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-729
2,4-dichlorophenyl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-730
2-chloro-4-fluorophenyl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-731
2-chloro-4,5-difluorophenyl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-732
4-bromo-2-chlorophenyl
Et
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-733
2-bromo-4-chlorophenyl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-734
2-bromo-4-fluorophenyl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-735
2-chloro-4-nitrophenyl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-736
3,5-dicyanophenyl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-737
4-cyano-2-fluorophenyl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-738
2-chloro-4-cyanophenyl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-739
pyridin-3-yl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-740
2-fluoropyridin-3-yl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-741
2-chloropyridin-3-yl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-742
2-bromopyridin-3-yl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-743
2-iodopyridin-3-yl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-744
2-(trifluoromethyl)pyridin-3-yl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-745
2-nitropyridin-3-yl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-746
2-cyanopyridin-3-yl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-747
6-fluoropyridin-3-yl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-748
6-chloropyridin-3-yl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-749
6-bromopyridin-3-yl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-750
6-iodopyridin-3-yl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-751
6-(trifluoromethyl)pyridin-3-yl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-752
6-nitropyridin-3-yl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-753
6-cyanopyridin-3-yl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-754
5-fluoropyridin-3-yl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-755
5-chloropyridin-3-yl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-756
5-bromopyridin-3-yl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-757
5-iodopyridin-3-yl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-758
5-(trifluoromethyl)pyridin-3-yl
CN
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-759
5-nitropyridin-3-yl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-760
5-cyanopyridin-3-yl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-761
4-fluoropyridin-3-yl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-762
4-chloropyridin-3-yl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-763
4-bromopyridin-3-yl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-764
4-iodopyridin-3-yl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-765
4-(trifluoromethyl)pyridin-3-yl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-766
4-nitropyridin-3-yl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-767
4-cyanopyridin-3-yl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-768
2,6-dichloropyridin-3-yl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-769
pyridin-3-yl N-oxide
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-770
pyridin-4-yl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-771
2-chloropyridin-4-yl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-772
3-bromopyridin-4-yl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-773
3,5-dichloropyridin-4-yl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-774
3-(trifluoromethyl)pyridin-4-yl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-775
2,6-dicyanopyridin-4-yl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-776
pyridin-4-yl N-oxide
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-777
pyridin-2-yl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-778
3-chloropyridin-2-yl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-779
4-bromopyridin-2-yl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-780
5-iodopyridin-2-yl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-781
6-chloropyridin-2-yl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-782
4-cyanopyridin-2-yl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


27-783
phenyl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-784
2-fluorophenyl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-785
3-fluorophenyl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-786
4-fluorophenyl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-787
2-chlorophenyl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-788
3-chlorophenyl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-789
4-chlorophenyl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-790
2-bromophenyl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-791
3-bromophenyl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-792
4-bromophenyl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-793
2-iodophenyl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-794
3-iodophenyl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-795
4-iodophenyl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-796
(2-trifluoromethyl)phenyl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-797
(3-trifluoromethyl)phenyl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-798
(4-trifluoromethyl)phenyl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-799
2-nitrophenyl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-800
3-nitrophenyl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-801
4-nitrophenyl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-802
2-cyanophenyl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-803
3-cyanophenyl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-804
4-cyanophenyl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-805
2,6-difluorophenyl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-806
3,4-dichlorophenyl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-807
2,4-dichlorophenyl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-808
2-chloro-4-fluorophenyl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-809
2-chloro-4,5-difluorophenyl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-810
4-bromo-2-chlorophenyl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-811
2-bromo-4-chlorophenyl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-812
2-bromo-4-fluorophenyl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-813
2-chloro-4-nitrophenyl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-814
3,5-dicyanophenyl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-815
4-cyano-2-fluorophenyl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-816
2-chloro-4-cyanophenyl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-817
pyridin-3-yl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-818
2-fluoropyridin-3-yl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-819
2-chloropyridin-3-yl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-820
2-bromopyridin-3-yl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-821
2-iodopyridin-3-yl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-822
2-(trifluoromethyl)pyridin-3-yl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-823
2-nitropyridin-3-yl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-824
2-cyanopyridin-3-yl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-825
6-fluoropyridin-3-yl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-826
6-chloropyridin-3-yl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-827
6-bromopyridin-3-yl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-828
6-iodopyridin-3-yl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-829
6-(trifluoromethyl)pyridin-3-yl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-830
6-nitropyridin-3-yl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-831
6-cyanopyridin-3-yl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-832
5-fluoropyridin-3-yl
C(O)Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-833
5-chloropyridin-3-yl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-834
5-bromopyridin-3-yl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-835
5-iodopyridin-3-yl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-836
5-(trifluoromethyl)pyridin-3-yl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-837
5-nitropyridin-3-yl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-838
5-cyanopyridin-3-yl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-839
4-fluoropyridin-3-yl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-840
4-chloropyridin-3-yl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-841
4-bromopyridin-3-yl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-842
4-iodopyridin-3-yl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-843
4-(trifluoromethyl)pyridin-3-yl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-844
4-nitropyridin-3-yl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-845
4-cyanopyridin-3-yl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-846
2,6-dichloropyridin-3-yl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-847
pyridin-3-yl N-oxide
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-848
pyridin-4-yl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-849
2-chloropyridin-4-yl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-850
3-bromopyridin-4-yl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-851
3,5-dichloropyridin-4-yl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-852
3-(trifluoromethyl)pyridin-4-yl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-853
2,6-dicyanopyridin-4-yl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-854
pyridin-4-yl N-oxide
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-855
pyridin-2-yl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-856
3-chloropyridin-2-yl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-857
4-bromopyridin-2-yl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-858
5-iodopyridin-2-yl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-859
6-chloropyridin-2-yl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-860
4-cyanopyridin-2-yl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


27-861
phenyl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-862
2-fluorophenyl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-863
3-fluorophenyl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-864
4-fluorophenyl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-865
2-chlorophenyl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-866
3-chlorophenyl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-867
4-chlorophenyl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-868
2-bromophenyl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-869
3-bromophenyl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-870
4-bromophenyl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-871
2-iodophenyl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-872
3-iodophenyl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-873
4-iodophenyl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-874
(2-trifluoromethyl)phenyl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-875
(3-trifluoromethyl)phenyl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-876
(4-trifluoromethyl)phenyl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-877
2-nitrophenyl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-878
3-nitrophenyl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-879
4-nitrophenyl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-880
2-cyanophenyl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-881
3-cyanophenyl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-882
4-cyanophenyl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-883
2,6-difluorophenyl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-884
3,4-dichlorophenyl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-885
2,4-dichlorophenyl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-886
2-chloro-4-fluorophenyl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-887
2-chloro-4,5-difluorophenyl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-888
4-bromo-2-chlorophenyl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-889
2-bromo-4-chlorophenyl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-890
2-bromo-4-fluorophenyl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-891
2-chloro-4-nitrophenyl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-892
3,5-dicyanophenyl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-893
4-cyano-2-fluorophenyl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-894
2-chloro-4-cyanophenyl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-895
pyridin-3-yl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-896
2-fluoropyridin-3-yl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-897
2-chloropyridin-3-yl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-898
2-bromopyridin-3-yl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-899
2-iodopyridin-3-yl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-900
2-(trifluoromethyl)pyridin-3-yl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-901
2-nitropyridin-3-yl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-902
2-cyanopyridin-3-yl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-903
6-fluoropyridin-3-yl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-904
6-chloropyridin-3-yl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-905
6-bromopyridin-3-yl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-906
6-iodopyridin-3-yl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-907
6-(trifluoromethyl)pyridin-3-yl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-908
6-nitropyridin-3-yl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-909
6-cyanopyridin-3-yl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-910
5-fluoropyridin-3-yl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-911
5-chloropyridin-3-yl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-912
5-bromopyridin-3-yl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-913
5-iodopyridin-3-yl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-914
5-(trifluoromethyl)pyridin-3-yl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-915
5-nitropyridin-3-yl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-916
5-cyanopyridin-3-yl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-917
4-fluoropyridin-3-yl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-918
4-chloropyridin-3-yl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-919
4-bromopyridin-3-yl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-920
4-iodopyridin-3-yl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-921
4-(trifluoromethyl)pyridin-3-yl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-922
4-nitropyridin-3-yl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-923
4-cyanopyridin-3-yl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-924
2,6-dichloropyridin-3-yl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-925
pyridin-3-yl N-oxide
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-926
pyridin-4-yl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-927
2-chloropyridin-4-yl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-928
3-bromopyridin-4-yl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-929
3,5-dichloropyridin-4-yl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-930
3-(trifluoromethyl)pyridin-4-yl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-931
2,6-dicyanopyridin-4-yl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-932
pyridin-4-yl N-oxide
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-933
pyridin-2-yl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-934
3-chloropyridin-2-yl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-935
4-bromopyridin-2-yl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-936
5-iodopyridin-2-yl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-937
6-chloropyridin-2-yl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-938
4-cyanopyridin-2-yl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


27-939
phenyl
Me
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


27-970
2-chloropyridin-3-yl
Me
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


27-995
phenyl
Me
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


27-1026
2-chloropyridin-3-yl
Me
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


27-1051
phenyl
Me
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


27-1082
2-chloropyridin-3-yl
Me
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


27-1107
phenyl
Me
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


27-1138
2-chloropyridin-3-yl
Me
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


27-1163
phenyl
Me
H
H
CF3
H
heptafluoroisopropyl
H
CF3


27-1183
3-cyanophenyl
Me
H
H
CF3
H
heptafluoroisopropyl
H
CF3


27-1184
4-cyanophenyl
Me
H
H
CF3
H
heptafluoroisopropyl
H
CF3


27-1199
2-chloropyridin-3-yl
Me
H
H
CF3
H
heptafluoroisopropyl
H
CF3


27-1231
phenyl
Me
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


27-1251
3-cyanophenyl
Me
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


27-1252
4-cyanophenyl
Me
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


27-1267
2-chloropyridin-3-yl
Me
H
H
CF3
H
nonafluoro-2-butyl
H
CF3











embedded image


















TABLE 28





compound











number
Q1
R1
R2
X3
Y1
Y2
Y3
Y4
Y5







28-1
phenyl
H
Me
H
Cl
H
heptafluoroisopropyl
H
OCF3


28-21
3-cyanophenyl
H
Me
H
Cl
H
heptafluoroisopropyl
H
OCF3


28-22
4-cyanophenyl
H
Me
H
Cl
H
heptafluoroisopropyl
H
OCF3


28-37
2-chloropyridin-3-yl
H
Me
H
Cl
H
heptafluoroisopropyl
H
OCF3


28-79
phenyl
H
Me
H
Cl
H
nonafluoro-2-butyl
H
OCF3


28-99
3-cyanophenyl
H
Me
H
Cl
H
nonafluoro-2-butyl
H
OCF3


28-100
4-cyanophenyl
H
Me
H
Cl
H
nonafluoro-2-butyl
H
OCF3


28-115
2-chloropyridin-3-yl
H
Me
H
Cl
H
nonafluoro-2-butyl
H
OCF3


28-157
phenyl
H
Me
H
Br
H
heptafluoroisopropyl
H
OCF3


28-177
3-cyanophenyl
H
Me
H
Br
H
heptafluoroisopropyl
H
OCF3


28-178
4-cyanophenyl
H
Me
H
Br
H
heptafluoroisopropyl
H
OCF3


28-193
2-chloropyridin-3-yl
H
Me
H
Br
H
heptafluoroisopropyl
H
OCF3


28-235
phenyl
H
Me
H
Br
H
nonafluoro-2-butyl
H
OCF3


28-255
3-cyanophenyl
H
Me
H
Br
H
nonafluoro-2-butyl
H
OCF3


28-256
4-cyanophenyl
H
Me
H
Br
H
nonafluoro-2-butyl
H
OCF3


28-271
2-chloropyridin-3-yl
H
Me
H
Br
H
nonafluoro-2-butyl
H
OCF3


28-313
phenyl
H
Me
H
I
H
heptafluoroisopropyl
H
OCF3


28-333
3-cyanophenyl
H
Me
H
I
H
heptafluoroisopropyl
H
OCF3


28-334
4-cyanophenyl
H
Me
H
I
H
heptafluoroisopropyl
H
OCF3


28-349
2-chloropyridin-3-yl
H
Me
H
I
H
heptafluoroisopropyl
H
OCF3


28-391
phenyl
H
Me
H
I
H
nonafluoro-2-butyl
H
OCF3


28-411
3-cyanophenyl
H
Me
H
I
H
nonafluoro-2-butyl
H
OCF3


28-412
4-cyanophenyl
H
Me
H
I
H
nonafluoro-2-butyl
H
OCF3


28-427
2-chloropyridin-3-yl
H
Me
H
I
H
nonafluoro-2-butyl
H
OCF3


28-469
phenyl
H
Me
H
F
H
heptafluoroisopropyl
H
CF3


28-470
phenyl
H
Me
H
Cl
H
heptafluoroisopropyl
H
CF3


28-481
3-iodophenyl
H
Me
H
Cl
H
pentafluoroethyl
H
CF3


28-482
4-iodophenyl
H
Me
H
Cl
H
pentafluoroethyl
H
CF3


28-484
(3-trifluoromethyl)phenyl
H
Et
H
Cl
H
heptafluoroisopropyl
H
CF3


28-489
2-cyanophenyl
H
Me
H
Cl
H
pentafluoroethyl
H
C2F5


28-490
3-cyanophenyl
H
Me
H
Cl
H
heptafluoroisopropyl
H
CF3


28-491
4-cyanophenyl
H
Me
H
Cl
H
heptafluoroisopropyl
H
CF3


28-494
2,4-dichlorophenyl
H
Me
H
Cl
H
heptafluoroisopropyl
H
C2F5


28-495
2-chloro-4-fluorophenyl
H
n-Pr
H
Cl
H
heptafluoroisopropyl
H
CF3


28-498
2-bromo-4-chlorophenyl
H
Me
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


28-505
2-fluoropyridin-3-yl
H
Me
H
Cl
H
pentafluoroethyl
H
CF3


28-506
2-chloropyridin-3-yl
H
Me
H
Cl
H
heptafluoroisopropyl
H
CF3


28-512
6-fluoropyridin-3-yl
H
i-Pr
H
Cl
H
heptafluoroisopropyl
H
CF3


28-519
5-fluoropyridin-3-yl
H
Me
H
Cl
H
heptafluoroisopropyl
H
C2F5


28-521
5-bromopyridin-3-yl
H
Me
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


28-522
5-iodopyridin-3-yl
H
Me
H
Cl
H
heptafluoroisopropyl
H
i-C3F7


28-524
5-nitropyridin-3-yl
H
Me
H
Cl
H
pentafluoroethyl
H
CF3


28-526
4-fluoropyridin-3-yl
H
Me
H
Cl
H
pentafluoroethyl
H
CF3


28-528
4-bromopyridin-3-yl
H
CH2CH═CH2
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


28-529
4-iodopyridin-3-yl
H
Me
H
Cl
H
heptafluoroisopropyl
H
i-C3F7


28-531
4-nitropyridin-3-yl
H
Me
Cl
Cl
H
heptafluoroisopropyl
H
CF3


28-535
pyridin-4-yl
H
CN
H
Cl
H
heptafluoroisopropyl
H
CF3


28-547
4-cyanopyridin-2-yl
H
Me
H
Cl
H
pentafluoroethyl
H
CF3


28-548
phenyl
H
Me
H
F
H
nonafluoro-2-butyl
H
CF3


28-549
phenyl
H
Me
H
Cl
H
nonafluoro-2-butyl
H
CF3


28-557
3-bromophenyl
H
CH2C≡CH
H
Cl
H
nonafluoro-2-butyl
H
CF3


28-562
(2-trifluoromethyl)phenyl
H
Me
H
Cl
H
nonafluoro-2-butyl
H
C2F5


28-564
(4-trifluoromethyl)phenyl
H
NH2
H
Cl
H
nonafluoro-2-butyl
H
CF3


28-569
3-cyanophenyl
H
Me
H
Cl
H
nonafluoro-2-butyl
H
CF3


28-570
4-cyanophenyl
H
Me
H
Cl
H
nonafluoro-2-butyl
H
CF3


28-577
2-bromo-4-chlorophenyl
H
C(O)OMe
H
Cl
H
nonafluoro-2-butyl
H
CF3


28-579
2-chloro-4-nitrophenyl
H
Me
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


28-585
2-chloropyridin-3-yl
H
Me
H
Cl
H
nonafluoro-2-butyl
H
CF3


28-598
5-fluoropyridin-3-yl
H
C(O)OEt
H
Cl
H
nonafluoro-2-butyl
H
C2F5


28-600
5-bromopyridin-3-yl
H
Me
H
Cl
H
nonafluoro-2-butyl
H
n-C3F7


28-601
5-iodopyridin-3-yl
H
Me
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


28-605
4-fluoropyridin-3-yl
H
Me
H
Cl
H
nonafluoro-2-butyl
H
C2F5


28-607
4-bromopyridin-3-yl
H
C(O)C(O)Me
H
Cl
H
nonafluoro-2-butyl
H
CF3


28-609
4-(trifluoromethyl)pyridin-3-yl
H
Me
H
Cl
H
nonafluoro-2-butyl
H
n-C3F7


28-610
4-nitropyridin-3-yl
H
C(O)C(O)Et
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


28-624
5-iodopyridin-2-yl
H
C(O)Me
H
Cl
H
nonafluoro-2-butyl
H
CF3


28-626
4-cyanopyridin-2-yl
H
C(O)Et
H
Cl
H
nonafluoro-2-butyl
H
C2F5


28-627
phenyl
H
Me
H
Br
H
heptafluoroisopropyl
H
CF3


28-628
2-fluorophenyl
H
Me
H
Br
H
heptafluoroisopropyl
H
CF3


28-641
(3-trifluoromethyl)phenyl
H
S(O)2Me
H
Br
H
heptafluoroisopropyl
H
CF3


28-647
3-cyanophenyl
H
Me
H
Br
H
heptafluoroisopropyl
H
CF3


28-648
4-cyanophenyl
H
Me
H
Br
H
heptafluoroisopropyl
H
CF3


28-659
4-cyano-2-fluorophenyl
H
S(O)2Et
H
Br
H
heptafluoroisopropyl
H
CF3


28-663
2-chloropyridin-3-yl
H
Me
H
Br
H
heptafluoroisopropyl
H
CF3


28-674
6-nitropyridin-3-yl
H
CH2Ph
H
Br
H
heptafluoroisopropyl
H
CF3


28-683
4-fluoropyridin-3-yl
H
CH2(3-Py)
H
Br
H
heptafluoroisopropyl
H
CF3


28-704
4-cyanopyridin-2-yl
H
CH2(3-Py—N-
H
Br
H
heptafluoroisopropyl
H
CF3





oxide)


28-705
phenyl
H
Me
H
Br
H
nonafluoro-2-butyl
H
CF3


28-706
2-fluorophenyl
H
Me
H
Br
H
nonafluoro-2-butyl
H
CF3


28-725
3-cyanophenyl
H
Me
H
Br
H
nonafluoro-2-butyl
H
CF3


28-726
4-cyanophenyl
H
Me
H
Br
H
nonafluoro-2-butyl
H
CF3


28-732
4-bromo-2-chlorophenyl
H
Et
H
Br
H
nonafluoro-2-butyl
H
CF3


28-741
2-chloropyridin-3-yl
H
Me
H
Br
H
nonafluoro-2-butyl
H
CF3


28-758
5-(trifluoromethyl)pyridin-3-yl
H
CN
H
Br
H
nonafluoro-2-butyl
H
CF3


28-783
phenyl
H
Me
H
I
H
heptafluoroisopropyl
H
CF3


28-784
2-fluorophenyl
H
Me
H
I
H
heptafluoroisopropyl
H
CF3


28-803
3-cyanophenyl
H
Me
H
I
H
heptafluoroisopropyl
H
CF3


28-804
4-cyanophenyl
H
Me
H
I
H
heptafluoroisopropyl
H
CF3


28-819
2-chloropyridin-3-yl
H
Me
H
I
H
heptafluoroisopropyl
H
CF3


28-832
5-fluoropyridin-3-yl
H
C(O)Me
H
I
H
heptafluoroisopropyl
H
CF3


28-861
phenyl
H
Me
H
I
H
nonafluoro-2-butyl
H
CF3


28-862
2-fluorophenyl
H
Me
H
I
H
nonafluoro-2-butyl
H
CF3


28-881
3-cyanophenyl
H
Me
H
I
H
nonafluoro-2-butyl
H
CF3


28-882
4-cyanophenyl
H
Me
H
I
H
nonafluoro-2-butyl
H
CF3


28-897
2-chloropyridin-3-yl
H
Me
H
I
H
nonafluoro-2-butyl
H
CF3


28-939
phenyl
H
Me
H
OCF3
H
heptafluoroisopropyl
H
OCF3


28-970
2-chloropyridin-3-yl
H
Me
H
OCF3
H
heptafluoroisopropyl
H
OCF3


28-995
phenyl
H
Me
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


28-1026
2-chloropyridin-3-yl
H
Me
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


28-1051
phenyl
H
Me
H
CF3
H
heptafluoroisopropyl
H
OCF3


28-1082
2-chloropyridin-3-yl
H
Me
H
CF3
H
heptafluoroisopropyl
H
OCF3


28-1107
phenyl
H
Me
H
CF3
H
nonafluoro-2-butyl
H
OCF3


28-1138
2-chloropyridin-3-yl
H
Me
H
CF3
H
nonafluoro-2-butyl
H
OCF3


28-1163
phenyl
H
Me
H
CF3
H
heptafluoroisopropyl
H
CF3


28-1183
3-cyanophenyl
H
Me
H
CF3
H
heptafluoroisopropyl
H
CF3


28-1184
4-cyanophenyl
H
Me
H
CF3
H
heptafluoroisopropyl
H
CF3


28-1199
2-chloropyridin-3-yl
H
Me
H
CF3
H
heptafluoroisopropyl
H
CF3


28-1231
phenyl
H
Me
H
CF3
H
nonafluoro-2-butyl
H
CF3


28-1251
3-cyanophenyl
H
Me
H
CF3
H
nonafluoro-2-butyl
H
CF3


28-1252
4-cyanophenyl
H
Me
H
CF3
H
nonafluoro-2-butyl
H
CF3


28-1267
2-chloropyridin-3-yl
H
Me
H
CF3
H
nonafluoro-2-butyl
H
CF3











embedded image


















TABLE 29





compound











number
Q1
R1
R2
X3
Y1
Y2
Y3
Y4
Y5







29-1
phenyl
Me
Me
H
Cl
H
heptafluoroisopropyl
H
OCF3


29-21
3-cyanophenyl
Me
Me
H
Cl
H
heptafluoroisopropyl
H
OCF3


29-22
4-cyanophenyl
Me
Me
H
Cl
H
heptafluoroisopropyl
H
OCF3


29-37
2-chloropyridin-3-yl
Me
Me
H
Cl
H
heptafluoroisopropyl
H
OCF3


29-79
phenyl
Me
Me
H
Cl
H
nonafluoro-2-butyl
H
OCF3


29-99
3-cyanophenyl
Me
Me
H
Cl
H
nonafluoro-2-butyl
H
OCF3


29-100
4-cyanophenyl
Me
Me
H
Cl
H
nonafluoro-2-butyl
H
OCF3


29-115
2-chloropyridin-3-yl
Me
Me
H
Cl
H
nonafluoro-2-butyl
H
OCF3


29-157
phenyl
Me
Me
H
Br
H
heptafluoroisopropyl
H
OCF3


29-177
3-cyanophenyl
Me
Me
H
Br
H
heptafluoroisopropyl
H
OCF3


29-178
4-cyanophenyl
Me
Me
H
Br
H
heptafluoroisopropyl
H
OCF3


29-193
2-chloropyridin-3-yl
Me
Me
H
Br
H
heptafluoroisopropyl
H
OCF3


29-235
phenyl
Me
Me
H
Br
H
nonafluoro-2-butyl
H
OCF3


29-255
3-cyanophenyl
Me
Me
H
Br
H
nonafluoro-2-butyl
H
OCF3


29-256
4-cyanophenyl
Me
Me
H
Br
H
nonafluoro-2-butyl
H
OCF3


29-271
2-chloropyridin-3-yl
Me
Me
H
Br
H
nonafluoro-2-butyl
H
OCF3


29-313
phenyl
Me
Me
H
I
H
heptafluoroisopropyl
H
OCF3


29-333
3-cyanophenyl
Me
Me
H
I
H
heptafluoroisopropyl
H
OCF3


29-334
4-cyanophenyl
Me
Me
H
I
H
heptafluoroisopropyl
H
OCF3


29-349
2-chloropyridin-3-yl
Me
Me
H
I
H
heptafluoroisopropyl
H
OCF3


29-391
phenyl
Me
Me
H
I
H
nonafluoro-2-butyl
H
OCF3


29-411
3-cyanophenyl
Me
Me
H
I
H
nonafluoro-2-butyl
H
OCF3


29-412
4-cyanophenyl
Me
Me
H
I
H
nonafluoro-2-butyl
H
OCF3


29-427
2-chloropyridin-3-yl
Me
Me
H
I
H
nonafluoro-2-butyl
H
OCF3


29-665
phenyl
Me
Me
H
F
H
heptafluoroisopropyl
H
CF3


29-666
phenyl
Me
Me
H
Cl
H
heptafluoroisopropyl
H
CF3


29-677
3-iodophenyl
Me
Me
H
Cl
H
pentafluoroethyl
H
CF3


29-678
4-iodophenyl
Me
Et
H
Cl
H
pentafluoroethyl
H
CF3


29-680
(3-trifluoromethyl)phenyl
Et
Me
H
Cl
H
heptafluoroisopropyl
H
CF3


29-682
2-nitrophenyl
Me
Me
Cl
Cl
H
heptafluoroisopropyl
H
CF3


29-685
2-cyanophenyl
Me
Me
H
Cl
H
pentafluoroethyl
H
C2F5


29-686
3-cyanophenyl
Me
Me
H
Cl
H
heptafluoroisopropyl
H
CF3


29-687
4-cyanophenyl
Me
Me
H
Cl
H
heptafluoroisopropyl
H
CF3


29-689
3,4-dichlorophenyl
Me
n-Pr
H
Cl
H
heptafluoroisopropyl
H
CF3


29-690
2,4-dichlorophenyl
Me
Me
H
Cl
H
heptafluoroisopropyl
H
C2F5


29-691
2-chloro-4-fluorophenyl
n-Pr
Me
H
Cl
H
heptafluoroisopropyl
H
CF3


29-694
2-bromo-4-chlorophenyl
Me
Me
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


29-701
2-fluoropyridin-3-yl
Me
Me
H
Cl
H
pentafluoroethyl
H
CF3


29-702
2-chloropyridin-3-yl
Me
Me
H
Cl
H
heptafluoroisopropyl
H
CF3


29-706
2-nitropyridin-3-yl
Me
i-Pr
H
Cl
H
heptafluoroisopropyl
H
CF3


29-708
6-fluoropyridin-3-yl
i-Pr
Me
H
Cl
H
heptafluoroisopropyl
H
CF3


29-715
5-fluoropyridin-3-yl
Me
Me
H
Cl
H
heptafluoroisopropyl
H
C2F5


29-717
5-bromopyridin-3-yl
Me
Me
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


29-718
5-iodopyridin-3-yl
Me
Me
H
Cl
H
heptafluoroisopropyl
H
i-C3F7


29-720
5-nitropyridin-3-yl
Me
Me
H
Cl
H
pentafluoroethyl
H
CF3


29-722
4-fluoropyridin-3-yl
Me
CH2CH═CH2
H
Cl
H
pentafluoroethyl
H
CF3


29-724
4-bromopyridin-3-yl
CH2CH═CH2
Me
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


29-725
4-iodopyridin-3-yl
Me
Me
H
Cl
H
heptafluoroisopropyl
H
i-C3F7


29-729
2,6-dichloropyridin-3-yl
Me
CN
H
Cl
H
heptafluoroisopropyl
H
CF3


29-731
pyridin-4-yl
CN
Me
H
Cl
H
heptafluoroisopropyl
H
CF3


29-743
4-cyanopyridin-2-yl
Me
Me
H
Cl
H
pentafluoroethyl
H
CF3


29-744
phenyl
Me
Me
H
F
H
nonafluoro-2-butyl
H
CF3


29-745
phenyl
Me
Me
H
Cl
H
nonafluoro-2-butyl
H
CF3


29-751
4-chlorophenyl
Me
CH2C≡CH
H
Cl
H
nonafluoro-2-butyl
H
CF3


29-753
3-bromophenyl
CH2C≡CH
Me
H
Cl
H
nonafluoro-2-butyl
H
CF3


29-758
(2-trifluoromethyl)phenyl
Me
NH2
H
Cl
H
nonafluoro-2-butyl
H
C2F5


29-760
(4-trifluoromethyl)phenyl
NH2
Me
H
Cl
H
nonafluoro-2-butyl
H
CF3


29-765
3-cyanophenyl
Me
Me
H
Cl
H
nonafluoro-2-butyl
H
CF3


29-766
4-cyanophenyl
Me
Me
H
Cl
H
nonafluoro-2-butyl
H
CF3


29-771
2-chloro-4,5-difluorophenyl
Me
C(O)OMe
H
Cl
H
nonafluoro-2-butyl
H
CF3


29-773
2-bromo-4-chlorophenyl
C(O)OMe
Me
H
Cl
H
nonafluoro-2-butyl
H
CF3


29-775
2-chloro-4-nitrophenyl
Me
Me
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


29-781
2-chloropyridin-3-yl
Me
Me
H
Cl
H
nonafluoro-2-butyl
H
CF3


29-792
6-nitropyridin-3-yl
Me
C(O)OEt
H
Cl
H
nonafluoro-2-butyl
H
CF3


29-794
5-fluoropyridin-3-yl
C(O)OEt
Me
H
Cl
H
nonafluoro-2-butyl
H
C2F5


29-796
5-bromopyridin-3-yl
Me
Me
H
Cl
H
nonafluoro-2-butyl
H
n-C3F7


29-797
5-iodopyridin-3-yl
Me
Me
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


29-801
4-fluoropyridin-3-yl
Me
C(O)C(O)Me
H
Cl
H
nonafluoro-2-butyl
H
C2F5


29-803
4-bromopyridin-3-yl
C(O)C(O)Me
Me
H
Cl
H
nonafluoro-2-butyl
H
CF3


29-804
4-iodopyridin-3-yl
Me
C(O)C(O)Et
H
Cl
H
nonafluoro-2-butyl
H
CF3


29-805
4-(trifluoromethyl)pyridin-3-yl
Me
Me
H
Cl
H
nonafluoro-2-butyl
H
n-C3F7


29-806
4-nitropyridin-3-yl
C(O)C(O)Et
Me
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


29-818
3-chloropyridin-2-yl
Me
C(O)Me
H
Cl
H
nonafluoro-2-butyl
H
CF3


29-820
5-iodopyridin-2-yl
C(O)Me
Me
H
Cl
H
nonafluoro-2-butyl
H
CF3


29-821
6-chloropyridin-2-yl
Me
C(O)Et
H
Cl
H
nonafluoro-2-butyl
H
CF3


29-822
4-cyanopyridin-2-yl
C(O)Et
Me
H
Cl
H
nonafluoro-2-butyl
H
C2F5


29-823
phenyl
Me
Me
H
Br
H
heptafluoroisopropyl
H
CF3


29-824
2-fluorophenyl
Me
Me
H
Br
H
heptafluoroisopropyl
H
CF3


29-835
4-iodophenyl
Me
S(O)2Me
H
Br
H
heptafluoroisopropyl
H
CF3


29-837
(3-trifluoromethyl)phenyl
S(O)2Me
Me
H
Br
H
heptafluoroisopropyl
H
CF3


29-843
3-cyanophenyl
Me
Me
H
Br
H
heptafluoroisopropyl
H
CF3


29-844
4-cyanophenyl
Me
Me
H
Br
H
heptafluoroisopropyl
H
CF3


29-853
2-chloro-4-nitrophenyl
Me
S(O)2Et
H
Br
H
heptafluoroisopropyl
H
CF3


29-855
4-cyano-2-fluorophenyl
S(O)2Et
Me
H
Br
H
heptafluoroisopropyl
H
CF3


29-859
2-chloropyridin-3-yl
Me
Me
H
Br
H
heptafluoroisopropyl
H
CF3


29-868
6-iodopyridin-3-yl
Me
CH2Ph
H
Br
H
heptafluoroisopropyl
H
CF3


29-870
6-nitropyridin-3-yl
CH2Ph
Me
H
Br
H
heptafluoroisopropyl
H
CF3


29-877
5-nitropyridin-3-yl
Me
CH2(3-Py)
H
Br
H
heptafluoroisopropyl
H
CF3


29-879
4-fluoropyridin-3-yl
CH2(3-Py)
Me
H
Br
H
heptafluoroisopropyl
H
CF3


29-898
5-iodopyridin-2-yl
Me
CH2(3-Py—N-
H
Br
H
heptafluoroisopropyl
H
CF3





oxide)


29-900
4-cyanopyridin-2-yl
CH2(3-Py—N-
Me
H
Br
H
heptafluoroisopropyl
H
CF3




oxide)


29-901
phenyl
Me
Me
H
Br
H
nonafluoro-2-butyl
H
CF3


29-902
2-fluorophenyl
Me
Me
H
Br
H
nonafluoro-2-butyl
H
CF3


29-921
3-cyanophenyl
Me
Me
H
Br
H
nonafluoro-2-butyl
H
CF3


29-922
4-cyanophenyl
Me
Me
H
Br
H
nonafluoro-2-butyl
H
CF3


29-926
2-chloro-4-fluorophenyl
Me
Et
H
Br
H
nonafluoro-2-butyl
H
CF3


29-928
4-bromo-2-chlorophenyl
Et
Me
H
Br
H
nonafluoro-2-butyl
H
CF3


29-937
2-chloropyridin-3-yl
Me
Me
H
Br
H
nonafluoro-2-butyl
H
CF3


29-952
5-bromopyridin-3-yl
Me
CN
H
Br
H
nonafluoro-2-butyl
H
CF3


29-954
5-(trifluoromethyl)pyridin-3-yl
CN
Me
H
Br
H
nonafluoro-2-butyl
H
CF3


29-979
phenyl
Me
Me
H
I
H
heptafluoroisopropyl
H
CF3


29-980
2-fluorophenyl
Me
Me
H
I
H
heptafluoroisopropyl
H
CF3


29-999
3-cyanophenyl
Me
Me
H
I
H
heptafluoroisopropyl
H
CF3


29-1000
4-cyanophenyl
Me
Me
H
I
H
heptafluoroisopropyl
H
CF3


29-1015
2-chloropyridin-3-yl
Me
Me
H
I
H
heptafluoroisopropyl
H
CF3


29-1026
6-nitropyridin-3-yl
Me
C(O)Me
H
I
H
heptafluoroisopropyl
H
CF3


29-1028
5-fluoropyridin-3-yl
C(O)Me
Me
H
I
H
heptafluoroisopropyl
H
CF3


29-1057
phenyl
Me
Me
H
I
H
nonafluoro-2-butyl
H
CF3


29-1058
2-fluorophenyl
Me
Me
H
I
H
nonafluoro-2-butyl
H
CF3


29-1077
3-cyanophenyl
Me
Me
H
I
H
nonafluoro-2-butyl
H
CF3


29-1078
4-cyanophenyl
Me
Me
H
I
H
nonafluoro-2-butyl
H
CF3


29-1093
2-chloropyridin-3-yl
Me
Me
H
I
H
nonafluoro-2-butyl
H
CF3


29-1331
phenyl
Me
Me
H
OCF3
H
heptafluoroisopropyl
H
OCF3


29-1362
2-chloropyridin-3-yl
Me
Me
H
OCF3
H
heptafluoroisopropyl
H
OCF3


29-1387
phenyl
Me
Me
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


29-1418
2-chloropyridin-3-yl
Me
Me
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


29-1443
phenyl
Me
Me
H
CF3
H
heptafluoroisopropyl
H
OCF3


29-1474
2-chloropyridin-3-yl
Me
Me
H
CF3
H
heptafluoroisopropyl
H
OCF3


29-1499
phenyl
Me
Me
H
CF3
H
nonafluoro-2-butyl
H
OCF3


29-1530
2-chloropyridin-3-yl
Me
Me
H
CF3
H
nonafluoro-2-butyl
H
OCF3


29-1555
phenyl
Me
Me
H
CF3
H
heptafluoroisopropyl
H
CF3


29-1575
3-cyanophenyl
Me
Me
H
CF3
H
heptafluoroisopropyl
H
CF3


29-1576
4-cyanophenyl
Me
Me
H
CF3
H
heptafluoroisopropyl
H
CF3


29-1591
2-chloropyridin-3-yl
Me
Me
H
CF3
H
heptafluoroisopropyl
H
CF3


29-1623
phenyl
Me
Me
H
CF3
H
nonafluoro-2-butyl
H
CF3


29-1643
3-cyanophenyl
Me
Me
H
CF3
H
nonafluoro-2-butyl
H
CF3


29-1644
4-cyanophenyl
Me
Me
H
CF3
H
nonafluoro-2-butyl
H
CF3


29-1659
2-chloropyridin-3-yl
Me
Me
H
CF3
H
nonafluoro-2-butyl
H
CF3











embedded image


















TABLE 30(1)





compound











number
Q1
R1
R2
X3
Y1
Y2
Y3
Y4
Y5







30-9
3-bromophenyl
H
Et
H
Cl
F
heptafluoroisopropyl
F
OCF3


30-39
2-iodopyridin-3-yl
H
H
H
Cl
Me
nonafluoro-2-butyl
Me
OCF3


30-144
phenyl
H
H
H
Cl
F
heptafluoroisopropyl
H
CF3


30-154
2-iodophenyl
H
H
H
Cl
F
heptafluoroisopropyl
Br
CF3


30-161
3-nitrophenyl
H
H
H
Cl
Br
heptafluoroisopropyl
Cl
CF3


30-168
2,4-dichlorophenyl
H
H
H
Cl
Me
nonafluoro-2-butyl
H
CF3


30-182
2-iodopyridin-3-yl
H
H
H
Cl
Me
nonafluoro-2-butyl
Me
n-C3F7


30-183
2-(trifluoromethyl)pyridin-3-yl
H
H
H
Cl
Me
nonafluoro-2-butyl
Et
i-C3F7


30-189
6-iodopyridin-3-yl
H
H
H
Cl
Et
nonafluoro-2-butyl
Me
n-C3F7


30-190
6-(trifluoromethyl)pyridin-3-yl
H
H
H
Cl
Et
nonafluoro-2-butyl
Et
i-C3F7


30-196
5-bromopyridin-3-yl
H
H
H
Br
n-Pr
heptafluoroisopropyl
Me
CF3


30-197
5-iodopyridin-3-yl
H
H
H
Br
n-Pr
heptafluoroisopropyl
Et
CF3


30-203
4-bromopyridin-3-yl
Me
n-Pr
H
Br
i-Pr
heptafluoroisopropyl
Me
CF3


30-204
4-iodopyridin-3-yl
H
H
H
Br
i-Pr
heptafluoroisopropyl
Et
CF3


30-210
pyridin-4-yl
H
H
H
Br
n-Bu
heptafluoroisopropyl
Me
CF3


30-211
2-chloropyridin-4-yl
H
H
H
Br
n-Bu
heptafluoroisopropyl
Et
CF3


30-217
pyridin-2-yl
H
H
H
Br
i-Bu
nonafluoro-2-butyl
Me
CF3


30-218
3-chloropyridin-2-yl
H
H
H
Br
i-Bu
nonafluoro-2-butyl
Et
CF3


30-224
2-fluorophenyl
H
H
H
Br
s-Bu
nonafluoro-2-butyl
Me
CF3


30-225
3-fluorophenyl
H
H
H
Br
s-Bu
nonafluoro-2-butyl
Et
CF3


30-231
3-bromophenyl
H
H
H
Br
F
nonafluoro-2-butyl
Me
CF3


30-232
4-bromophenyl
H
H
H
Br
F
nonafluoro-2-butyl
Et
CF3


30-238
(4-trifluoromethyl)phenyl
Et
i-Pr
H
Br
Cl
nonafluoro-2-butyl
Me
CF3


30-239
2-nitrophenyl
H
H
H
Br
Cl
nonafluoro-2-butyl
Et
CF3


30-245
4-cyanophenyl
H
H
H
I
Br
heptafluoroisopropyl
Me
CF3


30-246
2,6-difluorophenyl
H
H
H
I
Br
heptafluoroisopropyl
Et
CF3


30-252
2-bromo-4-chlorophenyl
n-Pr
Me
H
I
I
heptafluoroisopropyl
Me
CF3


30-253
2-bromo-4-fluorophenyl
H
H
H
I
I
heptafluoroisopropyl
Et
CF3


30-259
2-fluoropyridin-3-yl
H
H
H
I
Me
heptafluoroisopropyl
F
C2F5


30-260
2-chloropyridin-3-yl
H
H
H
I
Me
nonafluoro-2-butyl
Cl
CF3


30-263
2-(trifluoromethyl)pyridin-3-yl
H
H
H
I
Et
nonafluoro-2-butyl
F
CF3


30-264
2-nitropyridin-3-yl
H
H
H
I
Et
nonafluoro-2-butyl
Cl
CF3


30-267
6-chloropyridin-3-yl
H
H
H
I
n-Pr
nonafluoro-2-butyl
F
CF3


30-268
6-bromopyridin-3-yl
H
H
H
I
n-Pr
nonafluoro-2-butyl
Cl
CF3


30-271
6-nitropyridin-3-yl
H
H
H
I
i-Pr
nonafluoro-2-butyl
F
i-C3F7


30-272
6-cyanopyridin-3-yl
H
H
H
I
i-Pr
nonafluoro-2-butyl
Cl
CF3


30-275
5-bromopyridin-3-yl
H
H
H
I
n-Bu
nonafluoro-2-butyl
F
CF3


30-276
5-iodopyridin-3-yl
H
H
H
I
n-Bu
nonafluoro-2-butyl
Cl
CF3


30-279
5-cyanopyridin-3-yl
H
H
H
I
i-Bu
nonafluoro-2-butyl
F
CF3


30-280
4-fluoropyridin-3-yl
H
H
H
I
i-Bu
nonafluoro-2-butyl
Cl
CF3


30-283
4-iodopyridin-3-yl
i-Pr
n-Pr
H
I
s-Bu
nonafluoro-2-butyl
F
CF3


30-284
4-(trifluoromethyl)pyridin-3-yl
H
H
H
I
s-Bu
nonafluoro-2-butyl
Cl
CF3


30-295
3-bromophenyl
H
Et
H
OCF3
F
heptafluoroisopropyl
F
OCF3


30-325
2-iodopyridin-3-yl
H
H
H
OCF3
Me
nonafluoro-2-butyl
Me
OCF3


30-438
3-bromophenyl
H
Et
H
OCF3
F
heptafluoroisopropyl
F
CF3


30-468
2-iodopyridin-3-yl
H
H
H
OCF3
Me
nonafluoro-2-butyl
Me
CF3


30-581
3-bromophenyl
H
Et
H
CF3
F
heptafluoroisopropyl
F
CF3


30-611
2-iodopyridin-3-yl
H
H
H
CF3
Me
nonafluoro-2-butyl
Me
CF3











embedded image


















TABLE 31





compound











number
Q2
R1
R2
X3
Y1
Y2
Y3
Y4
Y5







31-1
2,2,2-trichloroethyl
H
H
H
F
H
heptafluoroisopropyl
H
OCF3


31-2
2,2,2-trichloroethyl
H
H
H
F
H
nonafluoro-2-butyl
H
OCF3


31-9
2-chloroethyl
H
H
Cl
Cl
H
heptafluoroisopropyl
H
OCF3


31-13
2,2,2-trichloroethyl
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


31-16
3-fluoro-n-propyl
H
H
H
Cl
H
pentafluoroethyl
H
OCF3


31-18
3-bromo-n-propyl
H
H
H
Cl
H
heptafluoroisopropyl
H
OC2F5


31-22
1,3-dichloro-2-propyl
H
H
H
Cl
H
pentafluoroethyl
H
OC2F5


31-26
4,4,4-trifluoro-n-butyl
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


31-36
2-bromoethyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
OC2F5


31-42
2,2,2-trichloroethyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


31-55
4,4,4-trifluoro-n-butyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


31-57
s-butyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
OC2F5


31-66
2-iodoethyl
H
H
H
Br
H
heptafluoroisopropyl
H
OC2F5


31-71
2,2,2-trichloroethyl
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


31-84
4,4,4-trifluoro-n-butyl
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


31-100
2,2,2-trichloroethyl
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


31-102
n-propyl
H
H
H
Br
H
nonafluoro-2-butyl
H
OC2F5


31-113
4,4,4-trifluoro-n-butyl
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


31-129
2,2,2-trichloroethyl
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


31-133
3-chloro-n-propyl
H
H
H
I
H
heptafluoroisopropyl
H
OC2F5


31-142
4,4,4-trifluoro-n-butyl
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


31-158
2,2,2-trichloroethyl
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


31-171
4,4,4-trifluoro-n-butyl
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


31-175
benzyl
H
H
H
I
H
nonafluoro-2-butyl
H
OC2F5


31-177
2,2,2-trichloroethyl
H
H
H
F
H
heptafluoroisopropyl
H
CF3


31-178
2,2,2-trichloroethyl
H
H
H
F
H
nonafluoro-2-butyl
H
CF3


31-179
methyl
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


31-180
ethyl
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


31-181
2-fluoroethyl
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


31-182
2-chloroethyl
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


31-183
2-bromoethyl
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


31-184
2-iodoethyl
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


31-185
2-cyanoethyl
H
H
H
Cl
H
heptafluoroisopropyl
H
C2F5


31-186
2,2-difluoroethyl
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


31-187
2,2-dichloroethyl
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


31-188
2,2,2-trifluoroethyl
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


31-189
2,2,2-trichloroethyl
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


31-190
2,2,2-tribromoethyl
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


31-191
n-propyl
H
H
H
Cl
H
pentafluoroethyl
H
CF3


31-192
3-fluoro-n-propyl
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


31-193
3-chloro-n-propyl
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


31-194
3-bromo-n-propyl
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


31-195
i-propyl
H
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


31-196
1,2-difluoro-2-propyl
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


31-197
1,3-difluoro-2-propyl
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


31-198
1,3-dichloro-2-propyl
H
H
H
Cl
H
pentafluoroethyl
H
CF3


31-199
1-chloro-3-fluoro-2-propyl
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


31-200
3,3,3-trifluoro-n-propyl
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


31-201
n-butyl
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


31-202
4,4,4-trifluoro-n-butyl
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


31-203
i-butyl
H
H
Cl
Cl
H
heptafluoroisopropyl
H
CF3


31-204
s-butyl
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


31-205
vinyl
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


31-206
benzyl
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


31-207
phenyl
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


31-208
methyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


31-209
ethyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


31-210
2-fluoroethyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


31-211
2-chloroethyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


31-212
2-bromoethyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


31-213
2-iodoethyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


31-214
2-cyanoethyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


31-215
2,2-difluoroethyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


31-216
2,2-dichloroethyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


31-217
2,2,2-trifluoroethyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


31-218
2,2,2-trichloroethyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


31-219
2,2,2-tribromoethyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


31-220
n-propyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


31-221
3-fluoro-n-propyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


31-222
3-chloro-n-propyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


31-223
3-bromo-n-propyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


31-224
i-propyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


31-225
1,2-difluoro-2-propyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


31-226
1,3-difluoro-2-propyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


31-227
1,3-dichloro-2-propyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


31-228
1-chloro-3-fluoro-2-propyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


31-229
3,3,3-trifluoro-n-propyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


31-230
n-butyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


31-231
4,4,4-trifluoro-n-butyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


31-232
i-butyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


31-233
s-butyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


31-234
vinyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


31-235
benzyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


31-236
phenyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


31-237
methyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


31-238
ethyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


31-239
2-fluoroethyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


31-240
2-chloroethyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


31-241
2-bromoethyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


31-242
2-iodoethyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


31-243
2-cyanoethyl
H
H
H
Br
H
heptafluoroisopropyl
H
C2F5


31-244
2,2-difluoroethyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


31-245
2,2-dichloroethyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


31-246
2,2,2-trifluoroethyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


31-247
2,2,2-trichloroethyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


31-248
2,2,2-tribromoethyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


31-249
n-propyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


31-250
3-fluoro-n-propyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


31-251
3-chloro-n-propyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


31-252
3-bromo-n-propyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


31-253
i-propyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


31-254
1,2-difluoro-2-propyl
H
H
H
Br
H
heptafluoroisopropyl
H
n-C3F7


31-255
1,3-difluoro-2-propyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


31-256
1,3-dichloro-2-propyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


31-257
1-chloro-3-fluoro-2-propyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


31-258
3,3,3-trifluoro-n-propyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


31-259
n-butyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


31-260
4,4,4-trifluoro-n-butyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


31-261
i-butyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


31-262
s-butyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


31-263
vinyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


31-264
benzyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


31-265
phenyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


31-266
methyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


31-267
ethyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


31-268
2-fluoroethyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


31-269
2-chloroethyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


31-270
2-bromoethyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


31-271
2-iodoethyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


31-272
2-cyanoethyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


31-273
2,2-difluoroethyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


31-274
2,2-dichloroethyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


31-275
2,2,2-trifluoroethyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


31-276
2,2,2-trichloroethyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


31-277
2,2,2-tribromoethyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


31-278
n-propyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


31-279
3-fluoro-n-propyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


31-280
3-chloro-n-propyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


31-281
3-bromo-n-propyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


31-282
i-propyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


31-283
1,2-difluoro-2-propyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


31-284
1,3-difluoro-2-propyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


31-285
1,3-dichloro-2-propyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


31-286
1-chloro-3-fluoro-2-propyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


31-287
3,3,3-trifluoro-n-propyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


31-288
n-butyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


31-289
4,4,4-trifluoro-n-butyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


31-290
i-butyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


31-291
s-butyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


31-292
vinyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


31-293
benzyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


31-294
phenyl
H
H
H
Br
H
nonafluoro-2-butyl
H
i-C3F7


31-295
methyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


31-296
ethyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


31-297
2-fluoroethyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


31-298
2-chloroethyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


31-299
2-bromoethyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


31-300
2-iodoethyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


31-301
2-cyanoethyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


31-302
2,2-difluoroethyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


31-303
2,2-dichloroethyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


31-304
2,2,2-trifluoroethyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


31-305
2,2,2-trichloroethyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


31-306
2,2,2-tribromoethyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


31-307
n-propyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


31-308
3-fluoro-n-propyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


31-309
3-chloro-n-propyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


31-310
3-bromo-n-propyl
H
H
H
I
H
heptafluoroisopropyl
H
C2F5


31-311
i-propyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


31-312
1,2-difluoro-2-propyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


31-313
1,3-difluoro-2-propyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


31-314
1,3-dichloro-2-propyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


31-315
1-chloro-3-fluoro-2-propyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


31-316
3,3,3-trifluoro-n-propyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


31-317
n-butyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


31-318
4,4,4-trifluoro-n-butyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


31-319
i-butyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


31-320
s-butyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


31-321
vinyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


31-322
benzyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


31-323
phenyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


31-324
methyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


31-325
ethyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


31-326
2-fluoroethyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


31-327
2-chloroethyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


31-328
2-bromoethyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


31-329
2-iodoethyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


31-330
2-cyanoethyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


31-331
2,2-difluoroethyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


31-332
2,2-dichloroethyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


31-333
2,2,2-trifluoroethyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


31-334
2,2,2-trichloroethyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


31-335
2,2,2-tribromoethyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


31-336
n-propyl
H
H
H
I
H
nonafluoro-2-butyl
H
n-C3F7


31-337
3-fluoro-n-propyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


31-338
3-chloro-n-propyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


31-339
3-bromo-n-propyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


31-340
i-propyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


31-341
1,2-difluoro-2-propyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


31-342
1,3-difluoro-2-propyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


31-343
1,3-dichloro-2-propyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


31-344
1-chloro-3-fluoro-2-propyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


31-345
3,3,3-trifluoro-n-propyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


31-346
n-butyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


31-347
4,4,4-trifluoro-n-butyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


31-348
i-butyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


31-349
s-butyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


31-350
vinyl
H
H
H
I
H
nonafluoro-2-butyl
H
i-C3F7


31-351
benzyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


31-352
phenyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


31-359
2-cyanoethyl
H
H
H
OCF3
H
heptafluoroisopropyl
H
OC2F5


31-363
2,2,2-trichloroethyl
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


31-364
2,2,2-tribromoethyl
H
H
H
OCF3
H
pentafluoroethyl
H
OCF3


31-373
1-chloro-3-fluoro-2-propyl
H
H
H
OC2F5
H
heptafluoroisopropyl
H
OC2F5


31-376
4,4,4-trifluoro-n-butyl
H
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


31-378
s-butyl
H
H
H
OC2F5
H
heptafluoroisopropyl
H
OCF3


31-391
2,2,2-trifluoroethyl
H
H
H
OC2F5
H
nonafluoro-2-butyl
H
OCF3


31-392
2,2,2-trichloroethyl
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


31-394
n-propyl
H
H
Cl
OCF3
H
nonafluoro-2-butyl
H
OC2F5


31-403
3,3,3-trifluoro-n-propyl
H
H
H
OC2F5
H
nonafluoro-2-butyl
H
OC2F5


31-405
4,4,4-trifluoro-n-butyl
H
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


31-417
2-cyanoethyl
H
H
H
CF3
H
heptafluoroisopropyl
H
OC2F5


31-421
2,2,2-trichloroethyl
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


31-423
n-propyl
H
H
H
C2F5
H
heptafluoroisopropyl
H
OC2F5


31-427
i-propyl
H
H
H
CF3
H
pentafluoroethyl
H
OCF3


31-432
3,3,3-trifluoro-n-propyl
H
H
Cl
n-C3F7
H
heptafluoroisopropyl
H
OCF3


31-434
4,4,4-trifluoro-n-butyl
H
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


31-437
vinyl
H
H
H
i-C3F7
H
heptafluoroisopropyl
H
OCF3


31-445
2-iodoethyl
H
H
H
C2F5
H
nonafluoro-2-butyl
H
OCF3


31-450
2,2,2-trichloroethyl
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


31-452
n-propyl
H
H
H
n-C3F7
H
nonafluoro-2-butyl
H
OCF3


31-456
i-propyl
H
H
H
CF3
H
nonafluoro-2-butyl
H
OC2F5


31-463
4,4,4-trifluoro-n-butyl
H
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


31-464
i-butyl
H
H
H
i-C3F7
H
nonafluoro-2-butyl
H
OCF3


31-467
benzyl
H
H
H
n-C3F7
H
nonafluoro-2-butyl
H
OC2F5


31-468
phenyl
H
H
H
i-C3F7
H
nonafluoro-2-butyl
H
OC2F5


31-479
2,2,2-trichloroethyl
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


31-482
3-fluoro-n-propyl
H
H
H
C2F5
H
heptafluoroisopropyl
H
CF3


31-485
i-propyl
H
H
H
i-C3F7
H
heptafluoroisopropyl
H
CF3


31-487
1,3-difluoro-2-propyl
H
H
H
CF3
H
pentafluoroethyl
H
CF3


31-490
3,3,3-trifluoro-n-propyl
H
H
H
C2F5
H
heptafluoroisopropyl
H
C2F5


31-492
4,4,4-trifluoro-n-butyl
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


31-493
i-butyl
H
H
H
C2F5
H
heptafluoroisopropyl
H
n-C3F7


31-495
vinyl
H
H
H
n-C3F7
H
heptafluoroisopropyl
H
CF3


31-508
2,2,2-trichloroethyl
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


31-520
n-butyl
H
H
H
C2F5
H
nonafluoro-2-butyl
H
i-C3F7


31-521
4,4,4-trifluoro-n-butyl
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


31-522
i-butyl
H
H
Cl
CF3
H
nonafluoro-2-butyl
H
CF3


31-524
vinyl
H
H
H
n-C3F7
H
nonafluoro-2-butyl
H
i-C3F7











embedded image


















TABLE 32





compound











number
Q2
R1
R2
X3
Y1
Y2
Y3
Y4
Y5







32-1
2,2,2-trichloroethyl
Me
H
H
F
H
heptafluoroisopropyl
H
OCF3


32-2
2,2,2-trichloroethyl
Me
H
H
F
H
nonafluoro-2-butyl
H
OCF3


32-13
2,2,2-trichloroethyl
Me
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


32-42
2,2,2-trichloroethyl
Me
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


32-71
2,2,2-trichloroethyl
Me
H
H
Br
H
heptafluoroisopropyl
H
OCF3


32-100
2,2,2-trichloroethyl
Me
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


32-129
2,2,2-trichloroethyl
Me
H
H
I
H
heptafluoroisopropyl
H
OCF3


32-158
2,2,2-trichloroethyl
Me
H
H
I
H
nonafluoro-2-butyl
H
OCF3


32-177
2,2,2-trichloroethyl
Me
H
H
F
H
heptafluoroisopropyl
H
CF3


32-178
2,2,2-trichloroethyl
Me
H
H
F
H
nonafluoro-2-butyl
H
CF3


32-185
2-cyanoethyl
Et
H
H
Cl
H
heptafluoroisopropyl
H
C2F5


32-189
2,2,2-trichloroethyl
Me
H
H
Cl
H
heptafluoroisopropyl
H
CF3


32-191
n-propyl
Me
H
H
Cl
H
pentafluoroethyl
H
CF3


32-195
i-propyl
n-Pr
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


32-198
1,3-dichloro-2-propyl
Me
H
H
Cl
H
pentafluoroethyl
H
CF3


32-199
1-chloro-3-fluoro-2-propyl
i-Pr
H
H
Cl
H
heptafluoroisopropyl
H
CF3


32-202
4,4,4-trifluoro-n-butyl
Me
H
H
Cl
H
heptafluoroisopropyl
H
CF3


32-203
i-butyl
CH2CH═CH2
H
H
Cl
H
heptafluoroisopropyl
H
CF3


32-207
phenyl
Me
H
Cl
Cl
H
heptafluoroisopropyl
H
CF3


32-209
ethyl
Me
H
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


32-214
2-cyanoethyl
CN
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


32-218
2,2,2-trichloroethyl
Me
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


32-220
n-propyl
CH2C≡CH
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


32-231
4,4,4-trifluoro-n-butyl
Me
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


32-232
i-butyl
NH2
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


32-243
2-cyanoethyl
Me
H
H
Br
H
heptafluoroisopropyl
H
C2F5


32-247
2,2,2-trichloroethyl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


32-249
n-propyl
C(O)OMe
H
H
Br
H
heptafluoroisopropyl
H
CF3


32-254
1,2-difluoro-2-propyl
Me
H
H
Br
H
heptafluoroisopropyl
H
n-C3F7


32-260
4,4,4-trifluoro-n-butyl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


32-263
vinyl
C(O)C(O)OMe
H
H
Br
H
heptafluoroisopropyl
H
CF3


32-276
2,2,2-trichloroethyl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


32-278
n-propyl
C(O)OEt
H
H
Br
H
nonafluoro-2-butyl
H
CF3


32-282
i-propyl
C(O)Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


32-289
4,4,4-trifluoro-n-butyl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


32-294
phenyl
C(O)C(O)OEt
H
H
Br
H
nonafluoro-2-butyl
H
i-C3F7


32-305
2,2,2-trichloroethyl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


32-310
3-bromo-n-propyl
C(O)Et
H
H
I
H
heptafluoroisopropyl
H
C2F5


32-318
4,4,4-trifluoro-n-butyl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


32-322
benzyl
S(O)2Me
H
H
I
H
heptafluoroisopropyl
H
CF3


32-330
2-cyanoethyl
S(O)2Et
H
H
I
H
nonafluoro-2-butyl
H
CF3


32-334
2,2,2-trichloroethyl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


32-336
n-propyl
CH2Ph
H
H
I
H
nonafluoro-2-butyl
H
n-C3F7


32-340
i-propyl
CH2(3-Py)
H
H
I
H
nonafluoro-2-butyl
H
CF3


32-347
4,4,4-trifluoro-n-butyl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


32-349
s-butyl
CH2(3-Py—N-
H
H
I
H
nonafluoro-2-butyl
H
CF3




oxide)


32-350
vinyl
Me
H
H
I
H
nonafluoro-2-butyl
H
i-C3F7


32-363
2,2,2-trichloroethyl
Me
H
H
OCF3
H
heptafluoroisopropyl
H
OCF3


32-392
2,2,2-trichloroethyl
Me
H
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


32-421
2,2,2-trichloroethyl
Me
H
H
CF3
H
heptafluoroisopropyl
H
OCF3


32-450
2,2,2-trichloroethyl
Me
H
H
CF3
H
nonafluoro-2-butyl
H
OCF3


32-479
2,2,2-trichloroethyl
Me
H
H
CF3
H
heptafluoroisopropyl
H
CF3


32-508
2,2,2-trichloroethyl
Me
H
H
CF3
H
nonafluoro-2-butyl
H
CF3











embedded image


















TABLE 33





compound











number
Q2
R1
R2
X3
Y1
Y2
Y3
Y4
Y5







33-1
2,2,2-trichloroethyl
H
Me
H
F
H
heptafluoroisopropyl
H
OCF3


33-2
2,2,2-trichloroethyl
H
Me
H
F
H
nonafluoro-2-butyl
H
OCF3


33-13
2,2,2-trichloroethyl
H
Me
H
Cl
H
heptafluoroisopropyl
H
OCF3


33-42
2,2,2-trichloroethyl
H
Me
H
Cl
H
nonafluoro-2-butyl
H
OCF3


33-71
2,2,2-trichloroethyl
H
Me
H
Br
H
heptafluoroisopropyl
H
OCF3


33-100
2,2,2-trichloroethyl
H
Me
H
Br
H
nonafluoro-2-butyl
H
OCF3


33-129
2,2,2-trichloroethyl
H
Me
H
I
H
heptafluoroisopropyl
H
OCF3


33-158
2,2,2-trichloroethyl
H
Me
H
I
H
nonafluoro-2-butyl
H
OCF3


33-177
2,2,2-trichloroethyl
H
Me
H
F
H
heptafluoroisopropyl
H
CF3


33-178
2,2,2-trichloroethyl
H
Me
H
F
H
nonafluoro-2-butyl
H
CF3


33-185
2-cyanoethyl
H
Et
H
Cl
H
heptafluoroisopropyl
H
C2F5


33-189
2,2,2-trichloroethyl
H
Me
H
Cl
H
heptafluoroisopropyl
H
CF3


33-191
n-propyl
H
Me
H
Cl
H
pentafluoroethyl
H
CF3


33-195
i-propyl
H
n-Pr
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


33-198
1,3-dichloro-2-propyl
H
Me
H
Cl
H
pentafluoroethyl
H
CF3


33-199
1-chloro-3-fluoro-2-propyl
H
i-Pr
H
Cl
H
heptafluoroisopropyl
H
CF3


33-203
i-butyl
H
CH2CH═CH2
H
Cl
H
heptafluoroisopropyl
H
CF3


33-207
phenyl
H
Me
Cl
Cl
H
heptafluoroisopropyl
H
CF3


33-209
ethyl
H
Me
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


33-214
2-cyanoethyl
H
CN
H
Cl
H
nonafluoro-2-butyl
H
CF3


33-218
2,2,2-trichloroethyl
H
Me
H
Cl
H
nonafluoro-2-butyl
H
CF3


33-220
n-propyl
H
CH2C≡CH
H
Cl
H
nonafluoro-2-butyl
H
CF3


33-232
i-butyl
H
NH2
H
Cl
H
nonafluoro-2-butyl
H
CF3


33-243
2-cyanoethyl
H
Me
H
Br
H
heptafluoroisopropyl
H
C2F5


33-247
2,2,2-trichloroethyl
H
Me
H
Br
H
heptafluoroisopropyl
H
CF3


33-249
n-propyl
H
C(O)OMe
H
Br
H
heptafluoroisopropyl
H
CF3


33-254
1,2-difluoro-2-propyl
H
Me
H
Br
H
heptafluoroisopropyl
H
n-C3F7


33-260
4,4,4-trifluoro-n-butyl
H
Me
H
Br
H
heptafluoroisopropyl
H
CF3


33-263
vinyl
H
C(O)C(O)OMe
H
Br
H
heptafluoroisopropyl
H
CF3


33-276
2,2,2-trichloroethyl
H
Me
H
Br
H
nonafluoro-2-butyl
H
CF3


33-278
n-propyl
H
C(O)OEt
H
Br
H
nonafluoro-2-butyl
H
CF3


33-282
i-propyl
H
C(O)Me
H
Br
H
nonafluoro-2-butyl
H
CF3


33-289
4,4,4-trifluoro-n-butyl
H
Me
H
Br
H
nonafluoro-2-butyl
H
CF3


33-294
phenyl
H
C(O)C(O)OEt
H
Br
H
nonafluoro-2-butyl
H
i-C3F7


33-305
2,2,2-trichloroethyl
H
Me
H
I
H
heptafluoroisopropyl
H
CF3


33-310
3-bromo-n-propyl
H
C(O)Et
H
I
H
heptafluoroisopropyl
H
C2F5


33-318
4,4,4-trifluoro-n-butyl
H
Me
H
I
H
heptafluoroisopropyl
H
CF3


33-322
benzyl
H
S(O)2Me
H
I
H
heptafluoroisopropyl
H
CF3


33-330
2-cyanoethyl
H
S(O)2Et
H
I
H
nonafluoro-2-butyl
H
CF3


33-334
2,2,2-trichloroethyl
H
Me
H
I
H
nonafluoro-2-butyl
H
CF3


33-336
n-propyl
H
CH2Ph
H
I
H
nonafluoro-2-butyl
H
n-C3F7


33-340
i-propyl
H
CH2(3-Py)
H
I
H
nonafluoro-2-butyl
H
CF3


33-347
4,4,4-trifluoro-n-butyl
H
Me
H
I
H
nonafluoro-2-butyl
H
CF3


33-349
s-butyl
H
CH2(3-Py—N-
H
I
H
nonafluoro-2-butyl
H
CF3





oxide)


33-350
vinyl
H
Me
H
I
H
nonafluoro-2-butyl
H
i-C3F7


33-363
2,2,2-trichloroethyl
H
Me
H
OCF3
H
heptafluoroisopropyl
H
OCF3


33-392
2,2,2-trichloroethyl
H
Me
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


33-421
2,2,2-trichloroethyl
H
Me
H
CF3
H
heptafluoroisopropyl
H
OCF3


33-450
2,2,2-trichloroethyl
H
Me
H
CF3
H
nonafluoro-2-butyl
H
OCF3


33-479
2,2,2-trichloroethyl
H
Me
H
CF3
H
heptafluoroisopropyl
H
CF3


33-508
2,2,2-trichloroethyl
H
Me
H
CF3
H
nonafluoro-2-butyl
H
CF3











embedded image


















TABLE 34





compound











number
Q2
R1
R2
X3
Y1
Y2
Y3
Y4
Y5







34-1
2,2,2-trichloroethyl
Me
Me
H
F
H
heptafluoroisopropyl
H
OCF3


34-2
2,2,2-trichloroethyl
Me
Me
H
F
H
nonafluoro-2-butyl
H
OCF3


34-13
2,2,2-trichloroethyl
Me
Me
H
Cl
H
heptafluoroisopropyl
H
OCF3


34-42
2,2,2-trichloroethyl
Me
Me
H
Cl
H
nonafluoro-2-butyl
H
OCF3


34-71
2,2,2-trichloroethyl
Me
Me
H
Br
H
heptafluoroisopropyl
H
OCF3


34-100
2,2,2-trichloroethyl
Me
Me
H
Br
H
nonafluoro-2-butyl
H
OCF3


34-129
2,2,2-trichloroethyl
Me
Me
H
I
H
heptafluoroisopropyl
H
OCF3


34-158
2,2,2-trichloroethyl
Me
Me
H
I
H
nonafluoro-2-butyl
H
OCF3


34-373
2,2,2-trichloroethyl
Me
Me
H
F
H
heptafluoroisopropyl
H
CF3


34-374
2,2,2-trichloroethyl
Me
Me
H
F
H
nonafluoro-2-butyl
H
CF3


34-380
2-iodoethyl
Me
Et
H
Cl
H
heptafluoroisopropyl
H
CF3


34-381
2-cyanoethyl
Et
Me
H
Cl
H
heptafluoroisopropyl
H
C2F5


34-385
2,2,2-trichloroethyl
Me
Me
H
Cl
H
heptafluoroisopropyl
H
CF3


34-387
n-propyl
Me
n-Pr
H
Cl
H
pentafluoroethyl
H
CF3


34-391
i-propyl
n-Pr
Me
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


34-394
1,3-dichloro-2-propyl
Me
Me
H
Cl
H
pentafluoroethyl
H
CF3


34-395
1-chloro-3-fluoro-2-propyl
i-Pr
Me
H
Cl
H
heptafluoroisopropyl
H
CF3


34-397
n-butyl
Me
i-Pr
H
Cl
H
heptafluoroisopropyl
H
CF3


34-399
i-butyl
CH2CH═CH2
Me
H
Cl
H
heptafluoroisopropyl
H
CF3


34-400
s-butyl
Me
CH2CH═CH2
H
Cl
H
heptafluoroisopropyl
H
CF3


34-401
vinyl
Me
CN
H
Cl
H
heptafluoroisopropyl
H
CF3


34-405
ethyl
Me
Me
H
Cl
H
nonafluoro-2-butyl
H
i-C3F7


34-410
2-cyanoethyl
CN
Me
H
Cl
H
nonafluoro-2-butyl
H
CF3


34-414
2,2,2-trichloroethyl
Me
Me
H
Cl
H
nonafluoro-2-butyl
H
CF3


34-415
2,2,2-tribromoethyl
Me
CH2C≡CH
H
Cl
H
nonafluoro-2-butyl
H
CF3


34-416
n-propyl
CH2C≡CH
Me
H
Cl
H
nonafluoro-2-butyl
H
CF3


34-420
i-propyl
Me
Me
Cl
Cl
H
nonafluoro-2-butyl
H
CF3


34-426
n-butyl
Me
NH2
H
Cl
H
nonafluoro-2-butyl
H
CF3


34-428
i-butyl
NH2
Me
H
Cl
H
nonafluoro-2-butyl
H
CF3


34-439
2-cyanoethyl
Me
C(O)OMe
H
Br
H
heptafluoroisopropyl
H
C2F5


34-443
2,2,2-trichloroethyl
Me
Me
H
Br
H
heptafluoroisopropyl
H
CF3


34-445
n-propyl
C(O)OMe
Me
H
Br
H
heptafluoroisopropyl
H
CF3


34-450
1,2-difluoro-2-propyl
Me
Me
H
Br
H
heptafluoroisopropyl
H
n-C3F7


34-456
4,4,4-trifluoro-n-butyl
Me
Me
H
Br
H
heptafluoroisopropyl
H
CF3


34-457
i-butyl
Me
C(O)C(O)OMe
H
Br
H
heptafluoroisopropyl
H
CF3


34-459
vinyl
C(O)C(O)OMe
Me
H
Br
H
heptafluoroisopropyl
H
CF3


34-468
2-cyanoethyl
Me
C(O)OEt
H
Br
H
nonafluoro-2-butyl
H
CF3


34-472
2,2,2-trichloroethyl
Me
Me
H
Br
H
nonafluoro-2-butyl
H
CF3


34-474
n-propyl
C(O)OEt
Me
H
Br
H
nonafluoro-2-butyl
H
CF3


34-477
3-bromo-n-propyl
Me
C(O)Me
H
Br
H
nonafluoro-2-butyl
H
CF3


34-478
i-propyl
C(O)Me
Me
H
Br
H
nonafluoro-2-butyl
H
CF3


34-485
4,4,4-trifluoro-n-butyl
Me
Me
H
Br
H
nonafluoro-2-butyl
H
CF3


34-486
i-butyl
Me
C(O)C(O)OEt
H
Br
H
nonafluoro-2-butyl
H
CF3


34-490
phenyl
C(O)C(O)OEt
Me
H
Br
H
nonafluoro-2-butyl
H
i-C3F7


34-501
2,2,2-trichloroethyl
Me
Me
H
I
H
heptafluoroisopropyl
H
CF3


34-503
n-propyl
Me
C(O)Et
H
I
H
heptafluoroisopropyl
H
CF3


34-506
3-bromo-n-propyl
C(O)Et
Me
H
I
H
heptafluoroisopropyl
H
C2F5


34-514
4,4,4-trifluoro-n-butyl
Me
Me
H
I
H
heptafluoroisopropyl
H
CF3


34-515
i-butyl
Me
S(O)2Me
H
I
H
heptafluoroisopropyl
H
CF3


34-518
benzyl
S(O)2Me
Me
H
I
H
heptafluoroisopropyl
H
CF3


34-525
2-iodoethyl
Me
S(O)2Et
H
I
H
nonafluoro-2-butyl
H
CF3


34-526
2-cyanoethyl
S(O)2Et
Me
H
I
H
nonafluoro-2-butyl
H
CF3


34-530
2,2,2-trichloroethyl
Me
Me
H
I
H
nonafluoro-2-butyl
H
CF3


34-531
2,2,2-tribromoethyl
Me
CH2Ph
H
I
H
nonafluoro-2-butyl
H
CF3


34-532
n-propyl
CH2Ph
Me
H
I
H
nonafluoro-2-butyl
H
n-C3F7


34-536
i-propyl
CH2(3-Py)
Me
H
I
H
nonafluoro-2-butyl
H
CF3


34-542
n-butyl
Me
CH2(3-Py)
H
I
H
nonafluoro-2-butyl
H
CF3


34-543
4,4,4-trifluoro-n-butyl
Me
Me
H
I
H
nonafluoro-2-butyl
H
CF3


34-545
s-butyl
CH2(3-Py—N-
Me
H
I
H
nonafluoro-2-butyl
H
CF3




oxide)


34-546
vinyl
Me
Me
H
I
H
nonafluoro-2-butyl
H
i-C3F7


34-548
phenyl
Me
CH2(3-Py—N-
H
I
H
nonafluoro-2-butyl
H
CF3





oxide)


34-755
2,2,2-trichloroethyl
Me
Me
H
OCF3
H
heptafluoroisopropyl
H
OCF3


34-784
2,2,2-trichloroethyl
Me
Me
H
OCF3
H
nonafluoro-2-butyl
H
OCF3


34-813
2,2,2-trichloroethyl
Me
Me
H
CF3
H
heptafluoroisopropyl
H
OCF3


34-842
2,2,2-trichloroethyl
Me
Me
H
CF3
H
nonafluoro-2-butyl
H
OCF3


34-871
2,2,2-trichloroethyl
Me
Me
H
CF3
H
heptafluoroisopropyl
H
CF3


34-900
2,2,2-trichloroethyl
Me
Me
H
CF3
H
nonafluoro-2-butyl
H
CF3











embedded image


















TABLE 35





compound











number
Q2
R1
R2
X3
Y1
Y2
Y3
Y4
Y5







35-9
2,2-dichloroethyl
H
Et
H
Cl
F
heptafluoroisopropyl
F
OCF3


35-39
2,2,2-trifluoroethyl
H
H
H
Cl
Me
nonafluoro-2-butyl
Me
OCF3


35-154
2,2,2-trichloroethyl
H
H
H
Cl
F
heptafluoroisopropyl
Br
CF3


35-183
2,2,2-trichloroethyl
H
H
H
Cl
Me
nonafluoro-2-butyl
Et
i-C3F7


35-189
i-propyl
H
H
Cl
Cl
Et
nonafluoro-2-butyl
Me
n-C3F7


35-190
1,2-difluoro-2-propyl
H
H
H
Cl
Et
nonafluoro-2-butyl
Et
i-C3F7


35-196
2-chloroethyl
H
H
H
Br
n-Pr
heptafluoroisopropyl
Me
CF3


35-197
2-bromoethyl
H
H
H
Br
n-Pr
heptafluoroisopropyl
Et
CF3


35-203
2,2,2-trichloroethyl
H
H
H
Br
i-Pr
heptafluoroisopropyl
Me
CF3


35-204
2,2,2-tribromoethyl
H
H
H
Br
i-Pr
heptafluoroisopropyl
Et
CF3


35-210
1,2-difluoro-2-propyl
H
H
H
Br
n-Bu
heptafluoroisopropyl
Me
CF3


35-211
1,3-difluoro-2-propyl
H
H
H
Br
n-Bu
heptafluoroisopropyl
Et
CF3


35-217
i-butyl
H
H
H
Br
i-Bu
nonafluoro-2-butyl
Me
CF3


35-218
s-butyl
H
H
H
Br
i-Bu
nonafluoro-2-butyl
Et
CF3


35-224
2-fluoroethyl
H
H
H
Br
s-Bu
nonafluoro-2-butyl
Me
CF3


35-225
2-chloroethyl
H
H
H
Br
s-Bu
nonafluoro-2-butyl
Et
CF3


35-231
2,2,2-trifluoroethyl
H
H
H
Br
F
nonafluoro-2-butyl
Me
CF3


35-232
2,2,2-trichloroethyl
H
H
H
Br
F
nonafluoro-2-butyl
Et
CF3


35-238
i-propyl
Et
i-Pr
H
Br
Cl
nonafluoro-2-butyl
Me
CF3


35-239
1,2-difluoro-2-propyl
H
H
H
Br
Cl
nonafluoro-2-butyl
Et
CF3


35-245
2-iodoethyl
H
H
H
I
Br
heptafluoroisopropyl
Me
CF3


35-246
2-cyanoethyl
H
H
H
I
Br
heptafluoroisopropyl
Et
CF3


35-252
n-propyl
n-Pr
Me
H
I
I
heptafluoroisopropyl
Me
CF3


35-253
3-fluoro-n-propyl
H
H
H
I
I
heptafluoroisopropyl
Et
CF3


35-259
1,3-dichloro-2-propyl
H
H
H
I
Me
heptafluoroisopropyl
F
C2F5


35-260
1-chloro-3-fluoro-2-propyl
H
H
H
I
Me
nonafluoro-2-butyl
Cl
CF3


35-261
3,3,3-trifluoro-n-propyl
H
H
H
I
Me
nonafluoro-2-butyl
Br
n-C3F7


35-262
n-butyl
H
H
H
I
Me
nonafluoro-2-butyl
I
i-C3F7


35-263
4,4,4-trifluoro-n-butyl
H
H
H
I
Et
nonafluoro-2-butyl
F
CF3


35-264
i-butyl
H
H
H
I
Et
nonafluoro-2-butyl
Cl
CF3


35-265
s-butyl
H
H
H
I
Et
nonafluoro-2-butyl
Br
CF3


35-266
vinyl
n-Pr
i-Pr
H
I
Et
nonafluoro-2-butyl
I
C2F5


35-267
benzyl
H
H
H
I
n-Pr
nonafluoro-2-butyl
F
CF3


35-268
phenyl
H
H
H
I
n-Pr
nonafluoro-2-butyl
Cl
CF3


35-271
2-fluoroethyl
H
H
H
I
i-Pr
nonafluoro-2-butyl
F
i-C3F7


35-272
2-chloroethyl
H
H
H
I
i-Pr
nonafluoro-2-butyl
Cl
CF3


35-273
2-bromoethyl
n-Pr
C(O)Me
H
I
i-Pr
nonafluoro-2-butyl
Br
CF3


35-274
2-iodoethyl
H
H
H
I
i-Pr
nonafluoro-2-butyl
I
CF3


35-275
2-cyanoethyl
H
H
H
I
n-Bu
nonafluoro-2-butyl
F
CF3


35-276
2,2-difluoroethyl
H
H
H
I
n-Bu
nonafluoro-2-butyl
Cl
CF3


35-279
2,2,2-trichloroethyl
H
H
H
I
i-Bu
nonafluoro-2-butyl
F
CF3


35-280
2,2,2-tribromoethyl
H
H
H
I
i-Bu
nonafluoro-2-butyl
Cl
CF3


35-283
3-chloro-n-propyl
i-Pr
n-Pr
H
I
s-Bu
nonafluoro-2-butyl
F
CF3


35-284
3-bromo-n-propyl
H
H
H
I
s-Bu
nonafluoro-2-butyl
Cl
CF3


35-301
3-chloro-n-propyl
n-Pr
H
H
OCF3
Cl
heptafluoroisopropyl
Br
OCF3


35-454
i-butyl
H
H
H
OCF3
Me
nonafluoro-2-butyl
H
CF3


35-582
2,2,2-trifluoroethyl
H
H
H
CF3
F
heptafluoroisopropyl
Cl
CF3











embedded image


















TABLE 36





compound











number
Q1
R1
R2
X2
Y1
Y2
Y3
Y4
Y5







36-1
phenyl
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


36-2
phenyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


36-3
phenyl
H
H
Cl
Br
H
heptafluoroisopropyl
H
CF3


36-4
phenyl
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


36-5
phenyl
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


36-6
phenyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


36-7
phenyl
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


36-8
phenyl
Me
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


36-9
phenyl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


36-10
phenyl
Me
H
H
CF3
H
heptafluoroisopropyl
H
CF3


36-11
phenyl
Me
H
H
I
H
nonafluoro-2-butyl
H
OCF3


36-12
phenyl
Me
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


36-13
phenyl
Me
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


36-14
phenyl
H
Me
H
Cl
H
heptafluoroisopropyl
H
OCF3


36-15
phenyl
H
Me
H
Br
H
heptafluoroisopropyl
H
CF3


36-16
phenyl
H
Me
H
CF3
H
heptafluoroisopropyl
H
CF3


36-17
phenyl
H
Me
H
I
H
nonafluoro-2-butyl
H
OCF3


36-18
phenyl
H
Me
H
Cl
H
nonafluoro-2-butyl
H
CF3


36-19
phenyl
H
Me
H
CF3
H
nonafluoro-2-butyl
H
CF3


36-20
phenyl
Me
Me
H
Cl
H
heptafluoroisopropyl
H
OCF3


36-21
phenyl
Me
Me
H
Br
H
heptafluoroisopropyl
H
CF3


36-22
phenyl
Me
Me
H
CF3
H
heptafluoroisopropyl
H
CF3


36-23
phenyl
Me
Me
H
I
H
nonafluoro-2-butyl
H
OCF3


36-24
phenyl
Me
Me
H
Cl
H
nonafluoro-2-butyl
H
CF3


36-25
phenyl
Me
Me
H
CF3
H
nonafluoro-2-butyl
H
CF3


36-26
phenyl
H
H
H
Cl
F
heptafluoroisopropyl
H
OCF3


36-27
phenyl
Me
H
H
Br
H
heptafluoroisopropyl
F
CF3


36-28
phenyl
H
Me
H
CF3
Cl
heptafluoroisopropyl
H
CF3


36-29
phenyl
H
H
H
I
H
nonafluoro-2-butyl
Cl
OCF3


36-30
phenyl
H
H
H
Cl
Br
nonafluoro-2-butyl
H
CF3


36-31
phenyl
H
H
H
Br
H
nonafluoro-2-butyl
I
CF3


36-32
phenyl
H
H
H
I
Me
nonafluoro-2-butyl
H
CF3


36-33
phenyl
H
H
H
CF3
H
nonafluoro-2-butyl
Et
CF3











embedded image


















TABLE 37





compound











number
Q1
R1
R2
X3
Y1
Y2
Y3
Y4
Y5







37-1
phenyl
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


37-2
phenyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


37-3
phenyl
H
H
Cl
I
H
heptafluoroisopropyl
H
CF3


37-4
phenyl
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


37-5
phenyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


37-6
phenyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


37-7
phenyl
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


37-8
phenyl
Me
H
H
Br
H
heptafluoroisopropyl
H
OCF3


37-9
phenyl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


37-10
phenyl
Me
H
H
CF3
H
heptafluoroisopropyl
H
CF3


37-11
phenyl
Me
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


37-12
phenyl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


37-13
phenyl
Me
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


37-14
phenyl
H
Me
H
Br
H
heptafluoroisopropyl
H
OCF3


37-15
phenyl
H
Me
H
I
H
heptafluoroisopropyl
H
CF3


37-16
phenyl
H
Me
H
CF3
H
heptafluoroisopropyl
H
CF3


37-17
phenyl
H
Me
H
Cl
H
nonafluoro-2-butyl
H
OCF3


37-18
phenyl
H
Me
H
Br
H
nonafluoro-2-butyl
H
CF3


37-19
phenyl
H
Me
H
CF3
H
nonafluoro-2-butyl
H
CF3


37-20
phenyl
Me
Me
H
Br
H
heptafluoroisopropyl
H
OCF3


37-21
phenyl
Me
Me
H
I
H
heptafluoroisopropyl
H
CF3


37-22
phenyl
Me
Me
H
CF3
H
heptafluoroisopropyl
H
CF3


37-23
phenyl
Me
Me
H
Cl
H
nonafluoro-2-butyl
H
OCF3


37-24
phenyl
Me
Me
H
Br
H
nonafluoro-2-butyl
H
CF3


37-25
phenyl
Me
Me
H
CF3
H
nonafluoro-2-butyl
H
CF3


37-26
phenyl
Me
H
H
Br
F
heptafluoroisopropyl
H
OCF3


37-27
phenyl
H
H
H
I
H
heptafluoroisopropyl
F
CF3


37-28
phenyl
H
Me
H
CF3
Cl
heptafluoroisopropyl
H
CF3


37-29
phenyl
H
H
H
Cl
H
nonafluoro-2-butyl
Cl
OCF3


37-30
phenyl
H
H
H
Br
Br
nonafluoro-2-butyl
H
CF3


37-31
phenyl
H
H
H
I
H
nonafluoro-2-butyl
I
CF3


37-32
phenyl
H
H
H
Cl
Me
nonafluoro-2-butyl
H
CF3


37-33
phenyl
H
H
H
CF3
H
nonafluoro-2-butyl
Et
CF3











embedded image


















TABLE 38





compound











number
Q1
R1
R2
X2
Y1
Y2
Y3
Y4
Y5







38-1
phenyl
H
H
H
I
H
heptafluoroisopropyl
H
OCF3


38-2
phenyl
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


38-3
phenyl
H
H
Cl
Cl
H
heptafluoroisopropyl
H
CF3


38-4
phenyl
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


38-5
phenyl
H
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


38-6
phenyl
H
H
H
I
H
nonafluoro-2-butyl
H
CF3


38-7
phenyl
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


38-8
phenyl
Me
H
H
I
H
heptafluoroisopropyl
H
OCF3


38-9
phenyl
Me
H
H
Cl
H
heptafluoroisopropyl
H
CF3


38-10
phenyl
Me
H
H
CF3
H
heptafluoroisopropyl
H
CF3


38-11
phenyl
Me
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


38-12
phenyl
Me
H
H
I
H
nonafluoro-2-butyl
H
CF3


38-13
phenyl
Me
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


38-14
phenyl
H
Me
H
I
H
heptafluoroisopropyl
H
OCF3


38-15
phenyl
H
Me
H
Cl
H
heptafluoroisopropyl
H
CF3


38-16
phenyl
H
Me
H
CF3
H
heptafluoroisopropyl
H
CF3


38-17
phenyl
H
Me
H
Br
H
nonafluoro-2-butyl
H
OCF3


38-18
phenyl
H
Me
H
I
H
nonafluoro-2-butyl
H
CF3


38-19
phenyl
H
Me
H
CF3
H
nonafluoro-2-butyl
H
CF3


38-20
phenyl
Me
Me
H
I
H
heptafluoroisopropyl
H
OCF3


38-21
phenyl
Me
Me
H
Cl
H
heptafluoroisopropyl
H
CF3


38-22
phenyl
Me
Me
H
CF3
H
heptafluoroisopropyl
H
CF3


38-23
phenyl
Me
Me
H
Br
H
nonafluoro-2-butyl
H
OCF3


38-24
phenyl
Me
Me
H
I
H
nonafluoro-2-butyl
H
CF3


38-25
phenyl
Me
Me
H
CF3
H
nonafluoro-2-butyl
H
CF3


38-26
phenyl
H
H
H
I
F
heptafluoroisopropyl
H
OCF3


38-27
phenyl
H
H
H
Cl
H
heptafluoroisopropyl
F
CF3


38-28
phenyl
Me
H
H
CF3
Cl
heptafluoroisopropyl
H
CF3


38-29
phenyl
H
H
H
Br
H
nonafluoro-2-butyl
Cl
OCF3


38-30
phenyl
H
Me
H
I
Br
nonafluoro-2-butyl
H
CF3


38-31
phenyl
H
H
H
Cl
H
nonafluoro-2-butyl
I
CF3


38-32
phenyl
H
H
H
Br
Me
nonafluoro-2-butyl
H
CF3


38-33
phenyl
H
H
H
CF3
H
nonafluoro-2-butyl
Et
CF3











embedded image


















TABLE 39





compound











number
Q1
R1
R2
X1
Y1
Y2
Y3
Y4
Y5







39-1
phenyl
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


39-2
phenyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


39-3
phenyl
H
H
Cl
Br
H
heptafluoroisopropyl
H
CF3


39-4
phenyl
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


39-5
phenyl
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


39-6
phenyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


39-7
phenyl
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


39-8
phenyl
Me
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


39-9
phenyl
Me
H
H
Br
H
heptafluoroisopropyl
H
CF3


39-10
phenyl
Me
H
H
CF3
H
heptafluoroisopropyl
H
CF3


39-11
phenyl
Me
H
H
I
H
nonafluoro-2-butyl
H
OCF3


39-12
phenyl
Me
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


39-13
phenyl
Me
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


39-14
phenyl
H
Me
H
Cl
H
heptafluoroisopropyl
H
OCF3


39-15
phenyl
H
Me
H
Br
H
heptafluoroisopropyl
H
CF3


39-16
phenyl
H
Me
H
CF3
H
heptafluoroisopropyl
H
CF3


39-17
phenyl
H
Me
H
I
H
nonafluoro-2-butyl
H
OCF3


39-18
phenyl
H
Me
H
Cl
H
nonafluoro-2-butyl
H
CF3


39-19
phenyl
H
Me
H
CF3
H
nonafluoro-2-butyl
H
CF3


39-20
phenyl
Me
Me
H
Cl
H
heptafluoroisopropyl
H
OCF3


39-21
phenyl
Me
Me
H
Br
H
heptafluoroisopropyl
H
CF3


39-22
phenyl
Me
Me
H
CF3
H
heptafluoroisopropyl
H
CF3


39-23
phenyl
Me
Me
H
I
H
nonafluoro-2-butyl
H
OCF3


39-24
phenyl
Me
Me
H
Cl
H
nonafluoro-2-butyl
H
CF3


39-25
phenyl
Me
Me
H
CF3
H
nonafluoro-2-butyl
H
CF3


39-26
phenyl
H
H
H
Cl
F
heptafluoroisopropyl
H
OCF3


39-27
phenyl
Me
H
H
Br
H
heptafluoroisopropyl
F
CF3


39-28
phenyl
H
Me
H
CF3
Cl
heptafluoroisopropyl
H
CF3


39-29
phenyl
H
H
H
I
H
nonafluoro-2-butyl
Cl
OCF3


39-30
phenyl
H
H
H
Cl
Br
nonafluoro-2-butyl
H
CF3


39-31
phenyl
H
H
H
Br
H
nonafluoro-2-butyl
I
CF3


39-32
phenyl
H
H
H
I
Me
nonafluoro-2-butyl
H
CF3


39-33
phenyl
H
H
H
CF3
H
nonafluoro-2-butyl
Et
CF3











embedded image


















TABLE 40





compound











number
Q1
R1
R2
X1
Y1
Y2
Y3
Y4
Y5







40-1
phenyl
H
H
H
Br
H
heptafluoroisopropyl
H
OCF3


40-2
phenyl
H
H
H
I
H
heptafluoroisopropyl
H
CF3


40-3
phenyl
H
H
Cl
I
H
heptafluoroisopropyl
H
CF3


40-4
phenyl
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


40-5
phenyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


40-6
phenyl
H
H
H
Br
H
nonafluoro-2-butyl
H
CF3


40-7
phenyl
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


40-8
phenyl
Me
H
H
Br
H
heptafluoroisopropyl
H
OCF3


40-9
phenyl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


40-10
phenyl
Me
H
H
CF3
H
heptafluoroisopropyl
H
CF3


40-11
phenyl
Me
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


40-12
phenyl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


40-13
phenyl
Me
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


40-14
phenyl
H
Me
H
Br
H
heptafluoroisopropyl
H
OCF3


40-15
phenyl
H
Me
H
I
H
heptafluoroisopropyl
H
CF3


40-16
phenyl
H
Me
H
CF3
H
heptafluoroisopropyl
H
CF3


40-17
phenyl
H
Me
H
Cl
H
nonafluoro-2-butyl
H
OCF3


40-18
phenyl
H
Me
H
Br
H
nonafluoro-2-butyl
H
CF3


40-19
phenyl
H
Me
H
CF3
H
nonafluoro-2-butyl
H
CF3


40-20
phenyl
Me
Me
H
Br
H
heptafluoroisopropyl
H
OCF3


40-21
phenyl
Me
Me
H
I
H
heptafluoroisopropyl
H
CF3


40-22
phenyl
Me
Me
H
CF3
H
heptafluoroisopropyl
H
CF3


40-23
phenyl
Me
Me
H
Cl
H
nonafluoro-2-butyl
H
OCF3


40-24
phenyl
Me
Me
H
Br
H
nonafluoro-2-butyl
H
CF3


40-25
phenyl
Me
Me
H
CF3
H
nonafluoro-2-butyl
H
CF3


40-26
phenyl
H
H
H
Br
F
heptafluoroisopropyl
H
OCF3


40-27
phenyl
H
H
H
I
H
heptafluoroisopropyl
F
CF3


40-28
phenyl
Me
H
H
CF3
Cl
heptafluoroisopropyl
H
CF3


40-29
phenyl
H
H
H
Cl
H
nonafluoro-2-butyl
Cl
OCF3


40-30
phenyl
H
H
H
Br
Br
nonafluoro-2-butyl
H
CF3


40-31
phenyl
H
H
H
I
H
nonafluoro-2-butyl
I
CF3


40-32
phenyl
H
H
H
Cl
Me
nonafluoro-2-butyl
H
CF3


40-33
phenyl
H
Me
H
CF3
H
nonafluoro-2-butyl
Et
CF3











embedded image


















TABLE 41





compound











number
Q2
R1
R2
X2
Y1
Y2
Y3
Y4
Y5







41-1
2,2,2-trichloroethyl
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


41-2
2,2,2-trichloroethyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


41-3
2,2,2-trichloroethyl
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


41-4
2,2,2-trichloroethyl
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


41-5
2,2,2-trichloroethyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


41-6
2,2,2-trichloroethyl
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


41-7
2,2,2-trichloroethyl
Me
H
H
Br
H
heptafluoroisopropyl
H
OCF3


41-8
2,2,2-trichloroethyl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


41-9
2,2,2-trichloroethyl
Me
H
H
CF3
H
heptafluoroisopropyl
H
CF3


41-10
2,2,2-trichloroethyl
Me
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


41-11
2,2,2-trichloroethyl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


41-12
2,2,2-trichloroethyl
Me
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


41-13
2,2,2-trichloroethyl
H
Me
H
I
H
heptafluoroisopropyl
H
OCF3


41-14
2,2,2-trichloroethyl
H
Me
H
Cl
H
heptafluoroisopropyl
H
CF3


41-15
2,2,2-trichloroethyl
H
Me
H
CF3
H
heptafluoroisopropyl
H
CF3


41-16
2,2,2-trichloroethyl
H
Me
H
Br
H
nonafluoro-2-butyl
H
OCF3


41-17
2,2,2-trichloroethyl
H
Me
H
I
H
nonafluoro-2-butyl
H
CF3


41-18
2,2,2-trichloroethyl
H
Me
H
CF3
H
nonafluoro-2-butyl
H
CF3


41-19
2,2,2-trichloroethyl
Me
Me
H
Cl
H
heptafluoroisopropyl
H
OCF3


41-20
2,2,2-trichloroethyl
Me
Me
H
Br
H
heptafluoroisopropyl
H
CF3


41-21
2,2,2-trichloroethyl
Me
Me
H
CF3
H
heptafluoroisopropyl
H
CF3


41-22
2,2,2-trichloroethyl
Me
Me
H
I
H
nonafluoro-2-butyl
H
OCF3


41-23
2,2,2-trichloroethyl
Me
Me
H
Cl
H
nonafluoro-2-butyl
H
CF3


41-24
2,2,2-trichloroethyl
Me
Me
H
CF3
H
nonafluoro-2-butyl
H
CF3


41-25
2,2,2-trichloroethyl
H
H
H
Br
F
heptafluoroisopropyl
H
OCF3


41-26
2,2,2-trichloroethyl
H
H
H
I
H
heptafluoroisopropyl
Cl
CF3


41-27
2,2,2-trichloroethyl
H
H
H
CF3
Br
heptafluoroisopropyl
H
CF3


41-28
2,2,2-trichloroethyl
H
H
H
I
H
nonafluoro-2-butyl
I
OCF3


41-29
2,2,2-trichloroethyl
H
H
H
Br
Me
nonafluoro-2-butyl
H
CF3


41-30
2,2,2-trichloroethyl
H
H
H
CF3
H
nonafluoro-2-butyl
Et
CF3


41-31
2,2,2-trichloroethyl
H
H
Cl
Br
H
heptafluoroisopropyl
H
CF3











embedded image


















TABLE 42





compound











number
Q2
R1
R2
X3
Y1
Y2
Y3
Y4
Y5







42-1
2,2,2-trichloroethyl
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


42-2
2,2,2-trichloroethyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


42-3
2,2,2-trichloroethyl
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


42-4
2,2,2-trichloroethyl
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


42-5
2,2,2-trichloroethyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


42-6
2,2,2-trichloroethyl
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


42-7
2,2,2-trichloroethyl
Me
H
H
Br
H
heptafluoroisopropyl
H
OCF3


42-8
2,2,2-trichloroethyl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


42-9
2,2,2-trichloroethyl
Me
H
H
CF3
H
heptafluoroisopropyl
H
CF3


42-10
2,2,2-trichloroethyl
Me
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


42-11
2,2,2-trichloroethyl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


42-12
2,2,2-trichloroethyl
Me
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


42-13
2,2,2-trichloroethyl
H
Me
H
I
H
heptafluoroisopropyl
H
OCF3


42-14
2,2,2-trichloroethyl
H
Me
H
Cl
H
heptafluoroisopropyl
H
CF3


42-15
2,2,2-trichloroethyl
H
Me
H
CF3
H
heptafluoroisopropyl
H
CF3


42-16
2,2,2-trichloroethyl
H
Me
H
Br
H
nonafluoro-2-butyl
H
OCF3


42-17
2,2,2-trichloroethyl
H
Me
H
I
H
nonafluoro-2-butyl
H
CF3


42-18
2,2,2-trichloroethyl
H
Me
H
CF3
H
nonafluoro-2-butyl
H
CF3


42-19
2,2,2-trichloroethyl
Me
Me
H
Cl
H
heptafluoroisopropyl
H
OCF3


42-20
2,2,2-trichloroethyl
Me
Me
H
Br
H
heptafluoroisopropyl
H
CF3


42-21
2,2,2-trichloroethyl
Me
Me
H
CF3
H
heptafluoroisopropyl
H
CF3


42-22
2,2,2-trichloroethyl
Me
Me
H
I
H
nonafluoro-2-butyl
H
OCF3


42-23
2,2,2-trichloroethyl
Me
Me
H
Cl
H
nonafluoro-2-butyl
H
CF3


42-24
2,2,2-trichloroethyl
Me
Me
H
CF3
H
nonafluoro-2-butyl
H
CF3


42-25
2,2,2-trichloroethyl
H
H
H
Br
F
heptafluoroisopropyl
H
OCF3


42-26
2,2,2-trichloroethyl
H
H
H
I
H
heptafluoroisopropyl
Cl
CF3


42-27
2,2,2-trichloroethyl
H
H
H
CF3
Br
heptafluoroisopropyl
H
CF3


42-28
2,2,2-trichloroethyl
H
H
H
I
H
nonafluoro-2-butyl
I
OCF3


42-29
2,2,2-trichloroethyl
H
H
H
Br
Me
nonafluoro-2-butyl
H
CF3


42-30
2,2,2-trichloroethyl
H
H
H
CF3
H
nonafluoro-2-butyl
Et
CF3


42-31
2,2,2-trichloroethyl
H
H
Cl
Br
H
heptafluoroisopropyl
H
CF3











embedded image


















TABLE 43





compound











number
Q2
R1
R2
X2
Y1
Y2
Y3
Y4
Y5







43-1
2,2,2-trichloroethyl
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


43-2
2,2,2-trichloroethyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


43-3
2,2,2-trichloroethyl
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


43-4
2,2,2-trichloroethyl
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


43-5
2,2,2-trichloroethyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


43-6
2,2,2-trichloroethyl
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


43-7
2,2,2-trichloroethyl
Me
H
H
Br
H
heptafluoroisopropyl
H
OCF3


43-8
2,2,2-trichloroethyl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


43-9
2,2,2-trichloroethyl
Me
H
H
CF3
H
heptafluoroisopropyl
H
CF3


43-10
2,2,2-trichloroethyl
Me
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


43-11
2,2,2-trichloroethyl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


43-12
2,2,2-trichloroethyl
Me
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


43-13
2,2,2-trichloroethyl
H
Me
H
I
H
heptafluoroisopropyl
H
OCF3


43-14
2,2,2-trichloroethyl
H
Me
H
Cl
H
heptafluoroisopropyl
H
CF3


43-15
2,2,2-trichloroethyl
H
Me
H
CF3
H
heptafluoroisopropyl
H
CF3


43-16
2,2,2-trichloroethyl
H
Me
H
Br
H
nonafluoro-2-butyl
H
OCF3


43-17
2,2,2-trichloroethyl
H
Me
H
I
H
nonafluoro-2-butyl
H
CF3


43-18
2,2,2-trichloroethyl
H
Me
H
CF3
H
nonafluoro-2-butyl
H
CF3


43-19
2,2,2-trichloroethyl
Me
Me
H
Cl
H
heptafluoroisopropyl
H
OCF3


43-20
2,2,2-trichloroethyl
Me
Me
H
Br
H
heptafluoroisopropyl
H
CF3


43-21
2,2,2-trichloroethyl
Me
Me
H
CF3
H
heptafluoroisopropyl
H
CF3


43-22
2,2,2-trichloroethyl
Me
Me
H
I
H
nonafluoro-2-butyl
H
OCF3


43-23
2,2,2-trichloroethyl
Me
Me
H
Cl
H
nonafluoro-2-butyl
H
CF3


43-24
2,2,2-trichloroethyl
Me
Me
H
CF3
H
nonafluoro-2-butyl
H
CF3


43-25
2,2,2-trichloroethyl
H
H
H
Br
F
heptafluoroisopropyl
H
OCF3


43-26
2,2,2-trichloroethyl
H
H
H
I
H
heptafluoroisopropyl
Cl
CF3


43-27
2,2,2-trichloroethyl
H
H
H
CF3
Br
heptafluoroisopropyl
H
CF3


43-28
2,2,2-trichloroethyl
H
H
H
I
H
nonafluoro-2-butyl
I
OCF3


43-29
2,2,2-trichloroethyl
H
H
H
Br
Me
nonafluoro-2-butyl
H
CF3


43-30
2,2,2-trichloroethyl
H
H
H
CF3
H
nonafluoro-2-butyl
Et
CF3


43-31
2,2,2-trichloroethyl
H
H
Cl
Br
H
heptafluoroisopropyl
H
CF3











embedded image


















TABLE 44





compound











number
Q2
R1
R2
X1
Y1
Y2
Y3
Y4
Y5







44-1
2,2,2-trichloroethyl
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


44-2
2,2,2-trichloroethyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


44-3
2,2,2-trichloroethyl
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


44-4
2,2,2-trichloroethyl
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


44-5
2,2,2-trichloroethyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


44-6
2,2,2-trichloroethyl
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


44-7
2,2,2-trichloroethyl
Me
H
H
Br
H
heptafluoroisopropyl
H
OCF3


44-8
2,2,2-trichloroethyl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


44-9
2,2,2-trichloroethyl
Me
H
H
CF3
H
heptafluoroisopropyl
H
CF3


44-10
2,2,2-trichloroethyl
Me
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


44-11
2,2,2-trichloroethyl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


44-12
2,2,2-trichloroethyl
Me
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


44-13
2,2,2-trichloroethyl
H
Me
H
I
H
heptafluoroisopropyl
H
OCF3


44-14
2,2,2-trichloroethyl
H
Me
H
Cl
H
heptafluoroisopropyl
H
CF3


44-15
2,2,2-trichloroethyl
H
Me
H
CF3
H
heptafluoroisopropyl
H
CF3


44-16
2,2,2-trichloroethyl
H
Me
H
Br
H
nonafluoro-2-butyl
H
OCF3


44-17
2,2,2-trichloroethyl
H
Me
H
I
H
nonafluoro-2-butyl
H
CF3


44-18
2,2,2-trichloroethyl
H
Me
H
CF3
H
nonafluoro-2-butyl
H
CF3


44-19
2,2,2-trichloroethyl
Me
Me
H
Cl
H
heptafluoroisopropyl
H
OCF3


44-20
2,2,2-trichloroethyl
Me
Me
H
Br
H
heptafluoroisopropyl
H
CF3


44-21
2,2,2-trichloroethyl
Me
Me
H
CF3
H
heptafluoroisopropyl
H
CF3


44-22
2,2,2-trichloroethyl
Me
Me
H
I
H
nonafluoro-2-butyl
H
OCF3


44-23
2,2,2-trichloroethyl
Me
Me
H
Cl
H
nonafluoro-2-butyl
H
CF3


44-24
2,2,2-trichloroethyl
Me
Me
H
CF3
H
nonafluoro-2-butyl
H
CF3


44-25
2,2,2-trichloroethyl
H
H
H
Br
F
heptafluoroisopropyl
H
OCF3


44-26
2,2,2-trichloroethyl
H
H
H
I
H
heptafluoroisopropyl
Cl
CF3


44-27
2,2,2-trichloroethyl
H
H
H
CF3
Br
heptafluoroisopropyl
H
CF3


44-28
2,2,2-trichloroethyl
H
H
H
I
H
nonafluoro-2-butyl
I
OCF3


44-29
2,2,2-trichloroethyl
H
H
H
Br
Me
nonafluoro-2-butyl
H
CF3


44-30
2,2,2-trichloroethyl
H
H
H
CF3
H
nonafluoro-2-butyl
Et
CF3


44-31
2,2,2-trichloroethyl
H
H
Cl
Br
H
heptafluoroisopropyl
H
CF3











embedded image


















TABLE 45





compound











number
Q2
R1
R2
X1
Y1
Y2
Y3
Y4
Y5







45-1
2,2,2-trichloroethyl
H
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


45-2
2,2,2-trichloroethyl
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


45-3
2,2,2-trichloroethyl
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


45-4
2,2,2-trichloroethyl
H
H
H
I
H
nonafluoro-2-butyl
H
OCF3


45-5
2,2,2-trichloroethyl
H
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


45-6
2,2,2-trichloroethyl
H
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


45-7
2,2,2-trichloroethyl
Me
H
H
Br
H
heptafluoroisopropyl
H
OCF3


45-8
2,2,2-trichloroethyl
Me
H
H
I
H
heptafluoroisopropyl
H
CF3


45-9
2,2,2-trichloroethyl
Me
H
H
CF3
H
heptafluoroisopropyl
H
CF3


45-10
2,2,2-trichloroethyl
Me
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


45-11
2,2,2-trichloroethyl
Me
H
H
Br
H
nonafluoro-2-butyl
H
CF3


45-12
2,2,2-trichloroethyl
Me
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


45-13
2,2,2-trichloroethyl
H
Me
H
I
H
heptafluoroisopropyl
H
OCF3


45-14
2,2,2-trichloroethyl
H
Me
H
Cl
H
heptafluoroisopropyl
H
CF3


45-15
2,2,2-trichloroethyl
H
Me
H
CF3
H
heptafluoroisopropyl
H
CF3


45-16
2,2,2-trichloroethyl
H
Me
H
Br
H
nonafluoro-2-butyl
H
OCF3


45-17
2,2,2-trichloroethyl
H
Me
H
I
H
nonafluoro-2-butyl
H
CF3


45-18
2,2,2-trichloroethyl
H
Me
H
CF3
H
nonafluoro-2-butyl
H
CF3


45-19
2,2,2-trichloroethyl
Me
Me
H
Cl
H
heptafluoroisopropyl
H
OCF3


45-20
2,2,2-trichloroethyl
Me
Me
H
Br
H
heptafluoroisopropyl
H
CF3


45-21
2,2,2-trichloroethyl
Me
Me
H
CF3
H
heptafluoroisopropyl
H
CF3


45-22
2,2,2-trichloroethyl
Me
Me
H
I
H
nonafluoro-2-butyl
H
OCF3


45-23
2,2,2-trichloroethyl
Me
Me
H
Cl
H
nonafluoro-2-butyl
H
CF3


45-24
2,2,2-trichloroethyl
Me
Me
H
CF3
H
nonafluoro-2-butyl
H
CF3


45-25
2,2,2-trichloroethyl
H
H
H
Br
F
heptafluoroisopropyl
H
OCF3


45-26
2,2,2-trichloroethyl
H
H
H
I
H
heptafluoroisopropyl
Cl
CF3


45-27
2,2,2-trichloroethyl
H
H
H
CF3
Br
heptafluoroisopropyl
H
CF3


45-28
2,2,2-trichloroethyl
H
H
H
I
H
nonafluoro-2-butyl
I
OCF3


45-29
2,2,2-trichloroethyl
H
H
H
Br
Me
nonafluoro-2-butyl
H
CF3


45-30
2,2,2-trichloroethyl
H
H
H
CF3
H
nonafluoro-2-butyl
Et
CF3


45-31
2,2,2-trichloroethyl
H
H
Cl
Br
H
heptafluoroisopropyl
H
CF3











embedded image




















TABLE 46





compound













number
Q1
R1
R2
A
X2
X3
Y1
Y2
Y3
Y4
Y5







46-1
phenyl
H
H
S
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


46-2
phenyl
H
H
S
H
H
Br
H
heptafluoroisopropyl
H
CF3


46-3
phenyl
H
H
S
H
H
CF3
H
heptafluoroisopropyl
H
CF3


46-4
phenyl
H
H
S
H
H
I
H
nonafluoro-2-butyl
H
OCF3


46-5
phenyl
H
H
S
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


46-6
phenyl
H
H
S
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


46-7
phenyl
H
H
O
H
H
Br
H
heptafluoroisopropyl
H
OCF3


46-8
phenyl
H
H
O
H
H
I
H
heptafluoroisopropyl
H
CF3


46-9
phenyl
H
H
O
H
H
CF3
H
heptafluoroisopropyl
H
CF3


46-10
phenyl
H
H
O
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


46-11
phenyl
H
H
O
H
H
Br
H
nonafluoro-2-butyl
H
CF3


46-12
phenyl
H
H
O
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


46-13
phenyl
H
H
NH
H
H
I
H
heptafluoroisopropyl
H
OCF3


46-14
phenyl
H
H
NH
H
H
Cl
H
heptafluoroisopropyl
H
CF3


46-15
phenyl
H
H
NH
H
H
CF3
H
heptafluoroisopropyl
H
CF3


46-16
phenyl
H
H
NH
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


46-17
phenyl
H
H
NH
H
H
I
H
nonafluoro-2-butyl
H
CF3


46-18
phenyl
H
H
NH
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


46-19
phenyl
Me
H
S
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


46-20
phenyl
Me
H
S
H
H
Br
H
heptafluoroisopropyl
H
CF3


46-21
phenyl
Me
H
S
H
H
CF3
H
heptafluoroisopropyl
H
CF3


46-22
phenyl
Me
H
S
H
H
I
H
nonafluoro-2-butyl
H
OCF3


46-23
phenyl
Me
H
S
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


46-24
phenyl
Me
H
S
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


46-25
phenyl
Me
H
O
H
H
Br
H
heptafluoroisopropyl
H
OCF3


46-26
phenyl
Me
H
O
H
H
I
H
heptafluoroisopropyl
H
CF3


46-27
phenyl
Me
H
O
H
H
CF3
H
heptafluoroisopropyl
H
CF3


46-28
phenyl
Me
H
O
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


46-29
phenyl
Me
H
O
H
H
Br
H
nonafluoro-2-butyl
H
CF3


46-30
phenyl
Me
H
O
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


46-31
phenyl
Me
H
NH
H
H
I
H
heptafluoroisopropyl
H
OCF3


46-32
phenyl
Me
H
NH
H
H
Cl
H
heptafluoroisopropyl
H
CF3


46-33
phenyl
Me
H
NH
H
H
CF3
H
heptafluoroisopropyl
H
CF3


46-34
phenyl
Me
H
NH
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


46-35
phenyl
Me
H
NH
H
H
I
H
nonafluoro-2-butyl
H
CF3


46-36
phenyl
Me
H
NH
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


46-37
phenyl
H
Me
S
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


46-38
phenyl
H
Me
S
H
H
Br
H
heptafluoroisopropyl
H
CF3


46-39
phenyl
H
Me
S
H
H
CF3
H
heptafluoroisopropyl
H
CF3


46-40
phenyl
H
Me
S
H
H
I
H
nonafluoro-2-butyl
H
OCF3


46-41
phenyl
H
Me
S
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


46-42
phenyl
H
Me
S
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


46-43
phenyl
H
Me
O
H
H
Br
H
heptafluoroisopropyl
H
OCF3


46-44
phenyl
H
Me
O
H
H
I
H
heptafluoroisopropyl
H
CF3


46-45
phenyl
H
Me
O
H
H
CF3
H
heptafluoroisopropyl
H
CF3


46-46
phenyl
H
Me
O
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


46-47
phenyl
H
Me
O
H
H
Br
H
nonafluoro-2-butyl
H
CF3


46-48
phenyl
H
Me
O
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


46-49
phenyl
H
Me
NH
H
H
I
H
heptafluoroisopropyl
H
OCF3


46-50
phenyl
H
Me
NH
H
H
Cl
H
heptafluoroisopropyl
H
CF3


46-51
phenyl
H
Me
NH
H
H
CF3
H
heptafluoroisopropyl
H
CF3


46-52
phenyl
H
Me
NH
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


46-53
phenyl
H
Me
NH
H
H
I
H
nonafluoro-2-butyl
H
CF3


46-54
phenyl
H
Me
NH
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


46-55
phenyl
Me
Me
S
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


46-56
phenyl
Me
Me
S
H
H
Br
H
heptafluoroisopropyl
H
CF3


46-57
phenyl
Me
Me
S
H
H
CF3
H
heptafluoroisopropyl
H
CF3


46-58
phenyl
Me
Me
S
H
H
I
H
nonafluoro-2-butyl
H
OCF3


46-59
phenyl
Me
Me
S
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


46-60
phenyl
Me
Me
S
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


46-61
phenyl
Me
Me
O
H
H
Br
H
heptafluoroisopropyl
H
OCF3


46-62
phenyl
Me
Me
O
H
H
I
H
heptafluoroisopropyl
H
CF3


46-63
phenyl
Me
Me
O
H
H
CF3
H
heptafluoroisopropyl
H
CF3


46-64
phenyl
Me
Me
O
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


46-65
phenyl
Me
Me
O
H
H
Br
H
nonafluoro-2-butyl
H
CF3


46-66
phenyl
Me
Me
O
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


46-67
phenyl
Me
Me
NH
H
H
I
H
heptafluoroisopropyl
H
OCF3


46-68
phenyl
Me
Me
NH
H
H
Cl
H
heptafluoroisopropyl
H
CF3


46-69
phenyl
Me
Me
NH
H
H
CF3
H
heptafluoroisopropyl
H
CF3


46-70
phenyl
Me
Me
NH
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


46-71
phenyl
Me
Me
NH
H
H
I
H
nonafluoro-2-butyl
H
CF3


46-72
phenyl
Me
Me
NH
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


46-73
phenyl
Me
H
S
H
H
Cl
F
heptafluoroisopropyl
H
OCF3


46-74
phenyl
H
H
S
H
H
Br
H
heptafluoroisopropyl
F
CF3


46-75
phenyl
H
H
S
H
H
CF3
Cl
heptafluoroisopropyl
H
CF3


46-76
phenyl
H
H
S
H
H
I
H
nonafluoro-2-butyl
Cl
OCF3


46-77
phenyl
H
H
S
H
H
Cl
Br
nonafluoro-2-butyl
H
CF3


46-78
phenyl
H
H
S
H
H
CF3
H
nonafluoro-2-butyl
Br
CF3


46-79
phenyl
H
H
O
H
H
Br
I
heptafluoroisopropyl
H
OCF3


46-80
phenyl
Me
H
O
H
H
I
H
heptafluoroisopropyl
I
CF3


46-81
phenyl
H
H
O
H
H
CF3
Me
heptafluoroisopropyl
H
CF3


46-82
phenyl
H
H
O
H
H
Cl
H
nonafluoro-2-butyl
Me
OCF3


46-83
phenyl
H
H
O
H
H
Br
F
nonafluoro-2-butyl
F
CF3


46-84
phenyl
H
H
O
H
H
CF3
Cl
nonafluoro-2-butyl
Cl
CF3


46-85
phenyl
H
H
NH
H
H
I
Br
heptafluoroisopropyl
Br
OCF3


46-86
phenyl
H
H
NH
H
H
Cl
I
heptafluoroisopropyl
I
CF3


46-87
phenyl
Me
H
NH
H
H
CF3
F
heptafluoroisopropyl
Me
CF3


46-88
phenyl
H
H
NH
H
H
Br
Cl
nonafluoro-2-butyl
Me
OCF3


46-89
phenyl
H
H
NH
H
H
I
Br
nonafluoro-2-butyl
Me
CF3


46-90
phenyl
H
H
NH
H
H
CF3
I
nonafluoro-2-butyl
Me
CF3











embedded image




















TABLE 47





compound













number
Q1
R1
R2
A
X1
X3
Y1
Y2
Y3
Y4
Y5







47-1
phenyl
H
H
S
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


47-2
phenyl
H
H
S
H
H
Br
H
heptafluoroisopropyl
H
CF3


47-3
phenyl
H
H
S
H
H
CF3
H
heptafluoroisopropyl
H
CF3


47-4
phenyl
H
H
S
H
H
I
H
nonafluoro-2-butyl
H
OCF3


47-5
phenyl
H
H
S
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


47-6
phenyl
H
H
S
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


47-7
phenyl
H
H
O
H
H
Br
H
heptafluoroisopropyl
H
OCF3


47-8
phenyl
H
H
O
H
H
I
H
heptafluoroisopropyl
H
CF3


47-9
phenyl
H
H
O
H
H
CF3
H
heptafluoroisopropyl
H
CF3


47-10
phenyl
H
H
O
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


47-11
phenyl
H
H
O
H
H
Br
H
nonafluoro-2-butyl
H
CF3


47-12
phenyl
H
H
O
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


47-13
phenyl
H
H
NH
H
H
I
H
heptafluoroisopropyl
H
OCF3


47-14
phenyl
H
H
NH
H
H
Cl
H
heptafluoroisopropyl
H
CF3


47-15
phenyl
H
H
NH
H
H
CF3
H
heptafluoroisopropyl
H
CF3


47-16
phenyl
H
H
NH
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


47-17
phenyl
H
H
NH
H
H
I
H
nonafluoro-2-butyl
H
CF3


47-18
phenyl
H
H
NH
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


47-19
phenyl
Me
H
S
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


47-20
phenyl
Me
H
S
H
H
Br
H
heptafluoroisopropyl
H
CF3


47-21
phenyl
Me
H
S
H
H
CF3
H
heptafluoroisopropyl
H
CF3


47-22
phenyl
Me
H
S
H
H
I
H
nonafluoro-2-butyl
H
OCF3


47-23
phenyl
Me
H
S
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


47-24
phenyl
Me
H
S
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


47-25
phenyl
Me
H
O
H
H
Br
H
heptafluoroisopropyl
H
OCF3


47-26
phenyl
Me
H
O
H
H
I
H
heptafluoroisopropyl
H
CF3


47-27
phenyl
Me
H
O
H
H
CF3
H
heptafluoroisopropyl
H
CF3


47-28
phenyl
Me
H
O
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


47-29
phenyl
Me
H
O
H
H
Br
H
nonafluoro-2-butyl
H
CF3


47-30
phenyl
Me
H
O
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


47-31
phenyl
Me
H
NH
H
H
I
H
heptafluoroisopropyl
H
OCF3


47-32
phenyl
Me
H
NH
H
H
Cl
H
heptafluoroisopropyl
H
CF3


47-33
phenyl
Me
H
NH
H
H
CF3
H
heptafluoroisopropyl
H
CF3


47-34
phenyl
Me
H
NH
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


47-35
phenyl
Me
H
NH
H
H
I
H
nonafluoro-2-butyl
H
CF3


47-36
phenyl
Me
H
NH
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


47-37
phenyl
H
Me
S
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


47-38
phenyl
H
Me
S
H
H
Br
H
heptafluoroisopropyl
H
CF3


47-39
phenyl
H
Me
S
H
H
CF3
H
heptafluoroisopropyl
H
CF3


47-40
phenyl
H
Me
S
H
H
I
H
nonafluoro-2-butyl
H
OCF3


47-41
phenyl
H
Me
S
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


47-42
phenyl
H
Me
S
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


47-43
phenyl
H
Me
O
H
H
Br
H
heptafluoroisopropyl
H
OCF3


47-44
phenyl
H
Me
O
H
H
I
H
heptafluoroisopropyl
H
CF3


47-45
phenyl
H
Me
O
H
H
CF3
H
heptafluoroisopropyl
H
CF3


47-46
phenyl
H
Me
O
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


47-47
phenyl
H
Me
O
H
H
Br
H
nonafluoro-2-butyl
H
CF3


47-48
phenyl
H
Me
O
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


47-49
phenyl
H
Me
NH
H
H
I
H
heptafluoroisopropyl
H
OCF3


47-50
phenyl
H
Me
NH
H
H
Cl
H
heptafluoroisopropyl
H
CF3


47-51
phenyl
H
Me
NH
H
H
CF3
H
heptafluoroisopropyl
H
CF3


47-52
phenyl
H
Me
NH
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


47-53
phenyl
H
Me
NH
H
H
I
H
nonafluoro-2-butyl
H
CF3


47-54
phenyl
H
Me
NH
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


47-55
phenyl
Me
Me
S
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


47-56
phenyl
Me
Me
S
H
H
Br
H
heptafluoroisopropyl
H
CF3


47-57
phenyl
Me
Me
S
H
H
CF3
H
heptafluoroisopropyl
H
CF3


47-58
phenyl
Me
Me
S
H
H
I
H
nonafluoro-2-butyl
H
OCF3


47-59
phenyl
Me
Me
S
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


47-60
phenyl
Me
Me
S
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


47-61
phenyl
Me
Me
O
H
H
Br
H
heptafluoroisopropyl
H
OCF3


47-62
phenyl
Me
Me
O
H
H
I
H
heptafluoroisopropyl
H
CF3


47-63
phenyl
Me
Me
O
H
H
CF3
H
heptafluoroisopropyl
H
CF3


47-64
phenyl
Me
Me
O
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


47-65
phenyl
Me
Me
O
H
H
Br
H
nonafluoro-2-butyl
H
CF3


47-66
phenyl
Me
Me
O
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


47-67
phenyl
Me
Me
NH
H
H
I
H
heptafluoroisopropyl
H
OCF3


47-68
phenyl
Me
Me
NH
H
H
Cl
H
heptafluoroisopropyl
H
CF3


47-69
phenyl
Me
Me
NH
H
H
CF3
H
heptafluoroisopropyl
H
CF3


47-70
phenyl
Me
Me
NH
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


47-71
phenyl
Me
Me
NH
H
H
I
H
nonafluoro-2-butyl
H
CF3


47-72
phenyl
Me
Me
NH
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


47-73
phenyl
Me
H
S
H
H
Cl
F
heptafluoroisopropyl
H
OCF3


47-74
phenyl
H
H
S
H
H
Br
H
heptafluoroisopropyl
F
CF3


47-75
phenyl
H
H
S
H
H
CF3
Cl
heptafluoroisopropyl
H
CF3


47-76
phenyl
H
H
S
H
H
I
H
nonafluoro-2-butyl
Cl
OCF3


47-77
phenyl
H
H
S
H
H
Cl
Br
nonafluoro-2-butyl
H
CF3


47-78
phenyl
H
H
S
H
H
CF3
H
nonafluoro-2-butyl
Br
CF3


47-79
phenyl
H
H
O
H
H
Br
I
heptafluoroisopropyl
H
OCF3


47-80
phenyl
Me
H
O
H
H
I
H
heptafluoroisopropyl
I
CF3


47-81
phenyl
H
H
O
H
H
CF3
Me
heptafluoroisopropyl
H
CF3


47-82
phenyl
H
H
O
H
H
Cl
H
nonafluoro-2-butyl
Me
OCF3


47-83
phenyl
H
H
O
H
H
Br
F
nonafluoro-2-butyl
F
CF3


47-84
phenyl
H
H
O
H
H
CF3
Cl
nonafluoro-2-butyl
Cl
CF3


47-85
phenyl
H
H
NH
H
H
I
Br
heptafluoroisopropyl
Br
OCF3


47-86
phenyl
H
H
NH
H
H
Cl
I
heptafluoroisopropyl
I
CF3


47-87
phenyl
Me
H
NH
H
H
CF3
F
heptafluoroisopropyl
Me
CF3


47-88
phenyl
H
H
NH
H
H
Br
Cl
nonafluoro-2-butyl
Me
OCF3


47-89
phenyl
H
H
NH
H
H
I
Br
nonafluoro-2-butyl
Me
CF3


47-90
phenyl
H
H
NH
H
H
CF3
I
nonafluoro-2-butyl
Me
CF3











embedded image




















TABLE 48





compound













number
Q1
R1
R2
A
X1
X2
Y1
Y2
Y3
Y4
Y5







48-1
phenyl
H
H
S
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


48-2
phenyl
H
H
S
H
H
Br
H
heptafluoroisopropyl
H
CF3


48-3
phenyl
H
H
S
H
H
CF3
H
heptafluoroisopropyl
H
CF3


48-4
phenyl
H
H
S
H
H
I
H
nonafluoro-2-butyl
H
OCF3


48-5
phenyl
H
H
S
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


48-6
phenyl
H
H
S
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


48-7
phenyl
H
H
O
H
H
Br
H
heptafluoroisopropyl
H
OCF3


48-8
phenyl
H
H
O
H
H
I
H
heptafluoroisopropyl
H
CF3


48-9
phenyl
H
H
O
H
H
CF3
H
heptafluoroisopropyl
H
CF3


48-10
phenyl
H
H
O
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


48-11
phenyl
H
H
O
H
H
Br
H
nonafluoro-2-butyl
H
CF3


48-12
phenyl
H
H
O
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


48-13
phenyl
H
H
NH
H
H
I
H
heptafluoroisopropyl
H
OCF3


48-14
phenyl
H
H
NH
H
H
Cl
H
heptafluoroisopropyl
H
CF3


48-15
phenyl
H
H
NH
H
H
CF3
H
heptafluoroisopropyl
H
CF3


48-16
phenyl
H
H
NH
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


48-17
phenyl
H
H
NH
H
H
I
H
nonafluoro-2-butyl
H
CF3


48-18
phenyl
H
H
NH
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


48-19
phenyl
Me
H
S
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


48-20
phenyl
Me
H
S
H
H
Br
H
heptafluoroisopropyl
H
CF3


48-21
phenyl
Me
H
S
H
H
CF3
H
heptafluoroisopropyl
H
CF3


48-22
phenyl
Me
H
S
H
H
I
H
nonafluoro-2-butyl
H
OCF3


48-23
phenyl
Me
H
S
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


48-24
phenyl
Me
H
S
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


48-25
phenyl
Me
H
O
H
H
Br
H
heptafluoroisopropyl
H
OCF3


48-26
phenyl
Me
H
O
H
H
I
H
heptafluoroisopropyl
H
CF3


48-27
phenyl
Me
H
O
H
H
CF3
H
heptafluoroisopropyl
H
CF3


48-28
phenyl
Me
H
O
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


48-29
phenyl
Me
H
O
H
H
Br
H
nonafluoro-2-butyl
H
CF3


48-30
phenyl
Me
H
O
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


48-31
phenyl
Me
H
NH
H
H
I
H
heptafluoroisopropyl
H
OCF3


48-32
phenyl
Me
H
NH
H
H
Cl
H
heptafluoroisopropyl
H
CF3


48-33
phenyl
Me
H
NH
H
H
CF3
H
heptafluoroisopropyl
H
CF3


48-34
phenyl
Me
H
NH
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


48-35
phenyl
Me
H
NH
H
H
I
H
nonafluoro-2-butyl
H
CF3


48-36
phenyl
Me
H
NH
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


48-37
phenyl
H
Me
S
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


48-38
phenyl
H
Me
S
H
H
Br
H
heptafluoroisopropyl
H
CF3


48-39
phenyl
H
Me
S
H
H
CF3
H
heptafluoroisopropyl
H
CF3


48-40
phenyl
H
Me
S
H
H
I
H
nonafluoro-2-butyl
H
OCF3


48-41
phenyl
H
Me
S
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


48-42
phenyl
H
Me
S
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


48-43
phenyl
H
Me
O
H
H
Br
H
heptafluoroisopropyl
H
OCF3


48-44
phenyl
H
Me
O
H
H
I
H
heptafluoroisopropyl
H
CF3


48-45
phenyl
H
Me
O
H
H
CF3
H
heptafluoroisopropyl
H
CF3


48-46
phenyl
H
Me
O
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


48-47
phenyl
H
Me
O
H
H
Br
H
nonafluoro-2-butyl
H
CF3


48-48
phenyl
H
Me
O
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


48-49
phenyl
H
Me
NH
H
H
I
H
heptafluoroisopropyl
H
OCF3


48-50
phenyl
H
Me
NH
H
H
Cl
H
heptafluoroisopropyl
H
CF3


48-51
phenyl
H
Me
NH
H
H
CF3
H
heptafluoroisopropyl
H
CF3


48-52
phenyl
H
Me
NH
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


48-53
phenyl
H
Me
NH
H
H
I
H
nonafluoro-2-butyl
H
CF3


48-54
phenyl
H
Me
NH
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


48-55
phenyl
Me
Me
S
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


48-56
phenyl
Me
Me
S
H
H
Br
H
heptafluoroisopropyl
H
CF3


48-57
phenyl
Me
Me
S
H
H
CF3
H
heptafluoroisopropyl
H
CF3


48-58
phenyl
Me
Me
S
H
H
I
H
nonafluoro-2-butyl
H
OCF3


48-59
phenyl
Me
Me
S
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


48-60
phenyl
Me
Me
S
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


48-61
phenyl
Me
Me
O
H
H
Br
H
heptafluoroisopropyl
H
OCF3


48-62
phenyl
Me
Me
O
H
H
I
H
heptafluoroisopropyl
H
CF3


48-63
phenyl
Me
Me
O
H
H
CF3
H
heptafluoroisopropyl
H
CF3


48-64
phenyl
Me
Me
O
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


48-65
phenyl
Me
Me
O
H
H
Br
H
nonafluoro-2-butyl
H
CF3


48-66
phenyl
Me
Me
O
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


48-67
phenyl
Me
Me
NH
H
H
I
H
heptafluoroisopropyl
H
OCF3


48-68
phenyl
Me
Me
NH
H
H
Cl
H
heptafluoroisopropyl
H
CF3


48-69
phenyl
Me
Me
NH
H
H
CF3
H
heptafluoroisopropyl
H
CF3


48-70
phenyl
Me
Me
NH
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


48-71
phenyl
Me
Me
NH
H
H
I
H
nonafluoro-2-butyl
H
CF3


48-72
phenyl
Me
Me
NH
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


48-73
phenyl
Me
H
S
H
H
Cl
F
heptafluoroisopropyl
H
OCF3


48-74
phenyl
H
H
S
H
H
Br
H
heptafluoroisopropyl
F
CF3


48-75
phenyl
H
H
S
H
H
CF3
Cl
heptafluoroisopropyl
H
CF3


48-76
phenyl
H
H
S
H
H
I
H
nonafluoro-2-butyl
Cl
OCF3


48-77
phenyl
H
H
S
H
H
Cl
Br
nonafluoro-2-butyl
H
CF3


48-78
phenyl
H
H
S
H
H
CF3
H
nonafluoro-2-butyl
Br
CF3


48-79
phenyl
H
H
O
H
H
Br
I
heptafluoroisopropyl
H
OCF3


48-80
phenyl
Me
H
O
H
H
I
H
heptafluoroisopropyl
I
CF3


48-81
phenyl
H
H
O
H
H
CF3
Me
heptafluoroisopropyl
H
CF3


48-82
phenyl
H
H
O
H
H
Cl
H
nonafluoro-2-butyl
Me
OCF3


48-83
phenyl
H
H
O
H
H
Br
F
nonafluoro-2-butyl
F
CF3


48-84
phenyl
H
H
O
H
H
CF3
Cl
nonafluoro-2-butyl
Cl
CF3


48-85
phenyl
H
H
NH
H
H
I
Br
heptafluoroisopropyl
Br
OCF3


48-86
phenyl
H
H
NH
H
H
Cl
I
heptafluoroisopropyl
I
CF3


48-87
phenyl
Me
H
NH
H
H
CF3
F
heptafluoroisopropyl
Me
CF3


48-88
phenyl
H
H
NH
H
H
Br
Cl
nonafluoro-2-butyl
Me
OCF3


48-89
phenyl
H
H
NH
H
H
I
Br
nonafluoro-2-butyl
Me
CF3


48-90
phenyl
H
H
NH
H
H
CF3
I
nonafluoro-2-butyl
Me
CF3











embedded image




















TABLE 49





compound













number
Q2
R1
R2
A
X2
X3
Y1
Y2
Y3
Y4
Y5







49-1
2,2,2-trichloroethyl
H
H
S
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


49-2
2,2,2-trichloroethyl
H
H
S
H
H
Br
H
heptafluoroisopropyl
H
CF3


49-3
2,2,2-trichloroethyl
H
H
S
H
H
CF3
H
heptafluoroisopropyl
H
CF3


49-4
2,2,2-trichloroethyl
H
H
S
H
H
I
H
nonafluoro-2-butyl
H
OCF3


49-5
2,2,2-trichloroethyl
H
H
S
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


49-6
2,2,2-trichloroethyl
H
H
S
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


49-7
2,2,2-trichloroethyl
H
H
O
H
H
Br
H
heptafluoroisopropyl
H
OCF3


49-8
2,2,2-trichloroethyl
H
H
O
H
H
I
H
heptafluoroisopropyl
H
CF3


49-9
2,2,2-trichloroethyl
H
H
O
H
H
CF3
H
heptafluoroisopropyl
H
CF3


49-10
2,2,2-trichloroethyl
H
H
O
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


49-11
2,2,2-trichloroethyl
H
H
O
H
H
Br
H
nonafluoro-2-butyl
H
CF3


49-12
2,2,2-trichloroethyl
H
H
O
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


49-13
2,2,2-trichloroethyl
H
H
NH
H
H
I
H
heptafluoroisopropyl
H
OCF3


49-14
2,2,2-trichloroethyl
H
H
NH
H
H
Cl
H
heptafluoroisopropyl
H
CF3


49-15
2,2,2-trichloroethyl
H
H
NH
H
H
CF3
H
heptafluoroisopropyl
H
CF3


49-16
2,2,2-trichloroethyl
H
H
NH
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


49-17
2,2,2-trichloroethyl
H
H
NH
H
H
I
H
nonafluoro-2-butyl
H
CF3


49-18
2,2,2-trichloroethyl
H
H
NH
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


49-19
2,2,2-trichloroethyl
Me
H
S
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


49-20
2,2,2-trichloroethyl
Me
H
S
H
H
Br
H
heptafluoroisopropyl
H
CF3


49-21
2,2,2-trichloroethyl
Me
H
S
H
H
CF3
H
heptafluoroisopropyl
H
CF3


49-22
2,2,2-trichloroethyl
Me
H
S
H
H
I
H
nonafluoro-2-butyl
H
OCF3


49-23
2,2,2-trichloroethyl
Me
H
S
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


49-24
2,2,2-trichloroethyl
Me
H
S
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


49-25
2,2,2-trichloroethyl
Me
H
O
H
H
Br
H
heptafluoroisopropyl
H
OCF3


49-26
2,2,2-trichloroethyl
Me
H
O
H
H
I
H
heptafluoroisopropyl
H
CF3


49-27
2,2,2-trichloroethyl
Me
H
O
H
H
CF3
H
heptafluoroisopropyl
H
CF3


49-28
2,2,2-trichloroethyl
Me
H
O
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


49-29
2,2,2-trichloroethyl
Me
H
O
H
H
Br
H
nonafluoro-2-butyl
H
CF3


49-30
2,2,2-trichloroethyl
Me
H
O
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


49-31
2,2,2-trichloroethyl
Me
H
NH
H
H
I
H
heptafluoroisopropyl
H
OCF3


49-32
2,2,2-trichloroethyl
Me
H
NH
H
H
Cl
H
heptafluoroisopropyl
H
CF3


49-33
2,2,2-trichloroethyl
Me
H
NH
H
H
CF3
H
heptafluoroisopropyl
H
CF3


49-34
2,2,2-trichloroethyl
Me
H
NH
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


49-35
2,2,2-trichloroethyl
Me
H
NH
H
H
I
H
nonafluoro-2-butyl
H
CF3


49-36
2,2,2-trichloroethyl
Me
H
NH
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


49-37
2,2,2-trichloroethyl
H
Me
S
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


49-38
2,2,2-trichloroethyl
H
Me
S
H
H
Br
H
heptafluoroisopropyl
H
CF3


49-39
2,2,2-trichloroethyl
H
Me
S
H
H
CF3
H
heptafluoroisopropyl
H
CF3


49-40
2,2,2-trichloroethyl
H
Me
S
H
H
I
H
nonafluoro-2-butyl
H
OCF3


49-41
2,2,2-trichloroethyl
H
Me
S
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


49-42
2,2,2-trichloroethyl
H
Me
S
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


49-43
2,2,2-trichloroethyl
H
Me
O
H
H
Br
H
heptafluoroisopropyl
H
OCF3


49-44
2,2,2-trichloroethyl
H
Me
O
H
H
I
H
heptafluoroisopropyl
H
CF3


49-45
2,2,2-trichloroethyl
H
Me
O
H
H
CF3
H
heptafluoroisopropyl
H
CF3


49-46
2,2,2-trichloroethyl
H
Me
O
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


49-47
2,2,2-trichloroethyl
H
Me
O
H
H
Br
H
nonafluoro-2-butyl
H
CF3


49-48
2,2,2-trichloroethyl
H
Me
O
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


49-49
2,2,2-trichloroethyl
H
Me
NH
H
H
I
H
heptafluoroisopropyl
H
OCF3


49-50
2,2,2-trichloroethyl
H
Me
NH
H
H
Cl
H
heptafluoroisopropyl
H
CF3


49-51
2,2,2-trichloroethyl
H
Me
NH
H
H
CF3
H
heptafluoroisopropyl
H
CF3


49-52
2,2,2-trichloroethyl
H
Me
NH
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


49-53
2,2,2-trichloroethyl
H
Me
NH
H
H
I
H
nonafluoro-2-butyl
H
CF3


49-54
2,2,2-trichloroethyl
H
Me
NH
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


49-55
2,2,2-trichloroethyl
Me
Me
S
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


49-56
2,2,2-trichloroethyl
Me
Me
S
H
H
Br
H
heptafluoroisopropyl
H
CF3


49-57
2,2,2-trichloroethyl
Me
Me
S
H
H
CF3
H
heptafluoroisopropyl
H
CF3


49-58
2,2,2-trichloroethyl
Me
Me
S
H
H
I
H
nonafluoro-2-butyl
H
OCF3


49-59
2,2,2-trichloroethyl
Me
Me
S
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


49-60
2,2,2-trichloroethyl
Me
Me
S
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


49-61
2,2,2-trichloroethyl
Me
Me
O
H
H
Br
H
heptafluoroisopropyl
H
OCF3


49-62
2,2,2-trichloroethyl
Me
Me
O
H
H
I
H
heptafluoroisopropyl
H
CF3


49-63
2,2,2-trichloroethyl
Me
Me
O
H
H
CF3
H
heptafluoroisopropyl
H
CF3


49-64
2,2,2-trichloroethyl
Me
Me
O
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


49-65
2,2,2-trichloroethyl
Me
Me
O
H
H
Br
H
nonafluoro-2-butyl
H
CF3


49-66
2,2,2-trichloroethyl
Me
Me
O
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


49-67
2,2,2-trichloroethyl
Me
Me
NH
H
H
I
H
heptafluoroisopropyl
H
OCF3


49-68
2,2,2-trichloroethyl
Me
Me
NH
H
H
Cl
H
heptafluoroisopropyl
H
CF3


49-69
2,2,2-trichloroethyl
Me
Me
NH
H
H
CF3
H
heptafluoroisopropyl
H
CF3


49-70
2,2,2-trichloroethyl
Me
Me
NH
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


49-71
2,2,2-trichloroethyl
Me
Me
NH
H
H
I
H
nonafluoro-2-butyl
H
CF3


49-72
2,2,2-trichloroethyl
Me
Me
NH
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


49-73
2,2,2-trichloroethyl
Me
H
S
H
H
Cl
F
heptafluoroisopropyl
H
OCF3


49-74
2,2,2-trichloroethyl
H
H
S
H
H
Br
H
heptafluoroisopropyl
F
CF3


49-75
2,2,2-trichloroethyl
H
H
S
H
H
CF3
Cl
heptafluoroisopropyl
H
CF3


49-76
2,2,2-trichloroethyl
H
H
S
H
H
I
H
nonafluoro-2-butyl
Cl
OCF3


49-77
2,2,2-trichloroethyl
H
H
S
H
H
Cl
Br
nonafluoro-2-butyl
H
CF3


49-78
2,2,2-trichloroethyl
H
H
S
H
H
CF3
H
nonafluoro-2-butyl
Br
CF3


49-79
2,2,2-trichloroethyl
H
H
O
H
H
Br
I
heptafluoroisopropyl
H
OCF3


49-80
2,2,2-trichloroethyl
Me
H
O
H
H
I
H
heptafluoroisopropyl
I
CF3


49-81
2,2,2-trichloroethyl
H
H
O
H
H
CF3
Me
heptafluoroisopropyl
H
CF3


49-82
2,2,2-trichloroethyl
H
H
O
H
H
Cl
H
nonafluoro-2-butyl
Me
OCF3


49-83
2,2,2-trichloroethyl
H
H
O
H
H
Br
F
nonafluoro-2-butyl
F
CF3


49-84
2,2,2-trichloroethyl
H
H
O
H
H
CF3
Cl
nonafluoro-2-butyl
Cl
CF3


49-85
2,2,2-trichloroethyl
H
H
NH
H
H
I
Br
heptafluoroisopropyl
Br
OCF3


49-86
2,2,2-trichloroethyl
H
H
NH
H
H
Cl
I
heptafluoroisopropyl
I
CF3


49-87
2,2,2-trichloroethyl
Me
H
NH
H
H
CF3
F
heptafluoroisopropyl
Me
CF3


49-88
2,2,2-trichloroethyl
H
H
NH
H
H
Br
Cl
nonafluoro-2-butyl
Me
OCF3


49-89
2,2,2-trichloroethyl
H
H
NH
H
H
I
Br
nonafluoro-2-butyl
Me
CF3


49-90
2,2,2-trichloroethyl
H
H
NH
H
H
CF3
I
nonafluoro-2-butyl
Me
CF3











embedded image




















TABLE 50





compound













number
Q2
R1
R2
A
X1
X3
Y1
Y2
Y3
Y4
Y5







50-1
2,2,2-trichloroethyl
H
H
S
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


50-2
2,2,2-trichloroethyl
H
H
S
H
H
Br
H
heptafluoroisopropyl
H
CF3


50-3
2,2,2-trichloroethyl
H
H
S
H
H
CF3
H
heptafluoroisopropyl
H
CF3


50-4
2,2,2-trichloroethyl
H
H
S
H
H
I
H
nonafluoro-2-butyl
H
OCF3


50-5
2,2,2-trichloroethyl
H
H
S
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


50-6
2,2,2-trichloroethyl
H
H
S
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


50-7
2,2,2-trichloroethyl
H
H
O
H
H
Br
H
heptafluoroisopropyl
H
OCF3


50-8
2,2,2-trichloroethyl
H
H
O
H
H
I
H
heptafluoroisopropyl
H
CF3


50-9
2,2,2-trichloroethyl
H
H
O
H
H
CF3
H
heptafluoroisopropyl
H
CF3


50-10
2,2,2-trichloroethyl
H
H
O
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


50-11
2,2,2-trichloroethyl
H
H
O
H
H
Br
H
nonafluoro-2-butyl
H
CF3


50-12
2,2,2-trichloroethyl
H
H
O
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


50-13
2,2,2-trichloroethyl
H
H
NH
H
H
I
H
heptafluoroisopropyl
H
OCF3


50-14
2,2,2-trichloroethyl
H
H
NH
H
H
Cl
H
heptafluoroisopropyl
H
CF3


50-15
2,2,2-trichloroethyl
H
H
NH
H
H
CF3
H
heptafluoroisopropyl
H
CF3


50-16
2,2,2-trichloroethyl
H
H
NH
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


50-17
2,2,2-trichloroethyl
H
H
NH
H
H
I
H
nonafluoro-2-butyl
H
CF3


50-18
2,2,2-trichloroethyl
H
H
NH
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


50-19
2,2,2-trichloroethyl
Me
H
S
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


50-20
2,2,2-trichloroethyl
Me
H
S
H
H
Br
H
heptafluoroisopropyl
H
CF3


50-21
2,2,2-trichloroethyl
Me
H
S
H
H
CF3
H
heptafluoroisopropyl
H
CF3


50-22
2,2,2-trichloroethyl
Me
H
S
H
H
I
H
nonafluoro-2-butyl
H
OCF3


50-23
2,2,2-trichloroethyl
Me
H
S
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


50-24
2,2,2-trichloroethyl
Me
H
S
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


50-25
2,2,2-trichloroethyl
Me
H
O
H
H
Br
H
heptafluoroisopropyl
H
OCF3


50-26
2,2,2-trichloroethyl
Me
H
O
H
H
I
H
heptafluoroisopropyl
H
CF3


50-27
2,2,2-trichloroethyl
Me
H
O
H
H
CF3
H
heptafluoroisopropyl
H
CF3


50-28
2,2,2-trichloroethyl
Me
H
O
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


50-29
2,2,2-trichloroethyl
Me
H
O
H
H
Br
H
nonafluoro-2-butyl
H
CF3


50-30
2,2,2-trichloroethyl
Me
H
O
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


50-31
2,2,2-trichloroethyl
Me
H
NH
H
H
I
H
heptafluoroisopropyl
H
OCF3


50-32
2,2,2-trichloroethyl
Me
H
NH
H
H
Cl
H
heptafluoroisopropyl
H
CF3


50-33
2,2,2-trichloroethyl
Me
H
NH
H
H
CF3
H
heptafluoroisopropyl
H
CF3


50-34
2,2,2-trichloroethyl
Me
H
NH
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


50-35
2,2,2-trichloroethyl
Me
H
NH
H
H
I
H
nonafluoro-2-butyl
H
CF3


50-36
2,2,2-trichloroethyl
Me
H
NH
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


50-37
2,2,2-trichloroethyl
H
Me
S
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


50-38
2,2,2-trichloroethyl
H
Me
S
H
H
Br
H
heptafluoroisopropyl
H
CF3


50-39
2,2,2-trichloroethyl
H
Me
S
H
H
CF3
H
heptafluoroisopropyl
H
CF3


50-40
2,2,2-trichloroethyl
H
Me
S
H
H
I
H
nonafluoro-2-butyl
H
OCF3


50-41
2,2,2-trichloroethyl
H
Me
S
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


50-42
2,2,2-trichloroethyl
H
Me
S
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


50-43
2,2,2-trichloroethyl
H
Me
O
H
H
Br
H
heptafluoroisopropyl
H
OCF3


50-44
2,2,2-trichloroethyl
H
Me
O
H
H
I
H
heptafluoroisopropyl
H
CF3


50-45
2,2,2-trichloroethyl
H
Me
O
H
H
CF3
H
heptafluoroisopropyl
H
CF3


50-46
2,2,2-trichloroethyl
H
Me
O
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


50-47
2,2,2-trichloroethyl
H
Me
O
H
H
Br
H
nonafluoro-2-butyl
H
CF3


50-48
2,2,2-trichloroethyl
H
Me
O
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


50-49
2,2,2-trichloroethyl
H
Me
NH
H
H
I
H
heptafluoroisopropyl
H
OCF3


50-50
2,2,2-trichloroethyl
H
Me
NH
H
H
Cl
H
heptafluoroisopropyl
H
CF3


50-51
2,2,2-trichloroethyl
H
Me
NH
H
H
CF3
H
heptafluoroisopropyl
H
CF3


50-52
2,2,2-trichloroethyl
H
Me
NH
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


50-53
2,2,2-trichloroethyl
H
Me
NH
H
H
I
H
nonafluoro-2-butyl
H
CF3


50-54
2,2,2-trichloroethyl
H
Me
NH
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


50-55
2,2,2-trichloroethyl
Me
Me
S
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


50-56
2,2,2-trichloroethyl
Me
Me
S
H
H
Br
H
heptafluoroisopropyl
H
CF3


50-57
2,2,2-trichloroethyl
Me
Me
S
H
H
CF3
H
heptafluoroisopropyl
H
CF3


50-58
2,2,2-trichloroethyl
Me
Me
S
H
H
I
H
nonafluoro-2-butyl
H
OCF3


50-59
2,2,2-trichloroethyl
Me
Me
S
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


50-60
2,2,2-trichloroethyl
Me
Me
S
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


50-61
2,2,2-trichloroethyl
Me
Me
O
H
H
Br
H
heptafluoroisopropyl
H
OCF3


50-62
2,2,2-trichloroethyl
Me
Me
O
H
H
I
H
heptafluoroisopropyl
H
CF3


50-63
2,2,2-trichloroethyl
Me
Me
O
H
H
CF3
H
heptafluoroisopropyl
H
CF3


50-64
2,2,2-trichloroethyl
Me
Me
O
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


50-65
2,2,2-trichloroethyl
Me
Me
O
H
H
Br
H
nonafluoro-2-butyl
H
CF3


50-66
2,2,2-trichloroethyl
Me
Me
O
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


50-67
2,2,2-trichloroethyl
Me
Me
NH
H
H
I
H
heptafluoroisopropyl
H
OCF3


50-68
2,2,2-trichloroethyl
Me
Me
NH
H
H
Cl
H
heptafluoroisopropyl
H
CF3


50-69
2,2,2-trichloroethyl
Me
Me
NH
H
H
CF3
H
heptafluoroisopropyl
H
CF3


50-70
2,2,2-trichloroethyl
Me
Me
NH
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


50-71
2,2,2-trichloroethyl
Me
Me
NH
H
H
I
H
nonafluoro-2-butyl
H
CF3


50-72
2,2,2-trichloroethyl
Me
Me
NH
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


50-73
2,2,2-trichloroethyl
Me
H
S
H
H
Cl
F
heptafluoroisopropyl
H
OCF3


50-74
2,2,2-trichloroethyl
H
H
S
H
H
Br
H
heptafluoroisopropyl
F
CF3


50-75
2,2,2-trichloroethyl
H
H
S
H
H
CF3
Cl
heptafluoroisopropyl
H
CF3


50-76
2,2,2-trichloroethyl
H
H
S
H
H
I
H
nonafluoro-2-butyl
Cl
OCF3


50-77
2,2,2-trichloroethyl
H
H
S
H
H
Cl
Br
nonafluoro-2-butyl
H
CF3


50-78
2,2,2-trichloroethyl
H
H
S
H
H
CF3
H
nonafluoro-2-butyl
Br
CF3


50-79
2,2,2-trichloroethyl
H
H
O
H
H
Br
I
heptafluoroisopropyl
H
OCF3


50-80
2,2,2-trichloroethyl
Me
H
O
H
H
I
H
heptafluoroisopropyl
I
CF3


50-81
2,2,2-trichloroethyl
H
H
O
H
H
CF3
Me
heptafluoroisopropyl
H
CF3


50-82
2,2,2-trichloroethyl
H
H
O
H
H
Cl
H
nonafluoro-2-butyl
Me
OCF3


50-83
2,2,2-trichloroethyl
H
H
O
H
H
Br
F
nonafluoro-2-butyl
F
CF3


50-84
2,2,2-trichloroethyl
H
H
O
H
H
CF3
Cl
nonafluoro-2-butyl
Cl
CF3


50-85
2,2,2-trichloroethyl
H
H
NH
H
H
I
Br
heptafluoroisopropyl
Br
OCF3


50-86
2,2,2-trichloroethyl
H
H
NH
H
H
Cl
I
heptafluoroisopropyl
I
CF3


50-87
2,2,2-trichloroethyl
Me
H
NH
H
H
CF3
F
heptafluoroisopropyl
Me
CF3


50-88
2,2,2-trichloroethyl
H
H
NH
H
H
Br
Cl
nonafluoro-2-butyl
Me
OCF3


50-89
2,2,2-trichloroethyl
H
H
NH
H
H
I
Br
nonafluoro-2-butyl
Me
CF3


50-90
2,2,2-trichloroethyl
H
H
NH
H
H
CF3
I
nonafluoro-2-butyl
Me
CF3











embedded image




















TABLE 51





compound













number
Q2
R1
R2
A
X1
X2
Y1
Y2
Y3
Y4
Y5







51-1
2,2,2-trichloroethyl
H
H
S
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


51-2
2,2,2-trichloroethyl
H
H
S
H
H
Br
H
heptafluoroisopropyl
H
CF3


51-3
2,2,2-trichloroethyl
H
H
S
H
H
CF3
H
heptafluoroisopropyl
H
CF3


51-4
2,2,2-trichloroethyl
H
H
S
H
H
I
H
nonafluoro-2-butyl
H
OCF3


51-5
2,2,2-trichloroethyl
H
H
S
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


51-6
2,2,2-trichloroethyl
H
H
S
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


51-7
2,2,2-trichloroethyl
H
H
O
H
H
Br
H
heptafluoroisopropyl
H
OCF3


51-8
2,2,2-trichloroethyl
H
H
O
H
H
I
H
heptafluoroisopropyl
H
CF3


51-9
2,2,2-trichloroethyl
H
H
O
H
H
CF3
H
heptafluoroisopropyl
H
CF3


51-10
2,2,2-trichloroethyl
H
H
O
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


51-11
2,2,2-trichloroethyl
H
H
O
H
H
Br
H
nonafluoro-2-butyl
H
CF3


51-12
2,2,2-trichloroethyl
H
H
O
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


51-13
2,2,2-trichloroethyl
H
H
NH
H
H
I
H
heptafluoroisopropyl
H
OCF3


51-14
2,2,2-trichloroethyl
H
H
NH
H
H
Cl
H
heptafluoroisopropyl
H
CF3


51-15
2,2,2-trichloroethyl
H
H
NH
H
H
CF3
H
heptafluoroisopropyl
H
CF3


51-16
2,2,2-trichloroethyl
H
H
NH
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


51-17
2,2,2-trichloroethyl
H
H
NH
H
H
I
H
nonafluoro-2-butyl
H
CF3


51-18
2,2,2-trichloroethyl
H
H
NH
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


51-19
2,2,2-trichloroethyl
Me
H
S
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


51-20
2,2,2-trichloroethyl
Me
H
S
H
H
Br
H
heptafluoroisopropyl
H
CF3


51-21
2,2,2-trichloroethyl
Me
H
S
H
H
CF3
H
heptafluoroisopropyl
H
CF3


51-22
2,2,2-trichloroethyl
Me
H
S
H
H
I
H
nonafluoro-2-butyl
H
OCF3


51-23
2,2,2-trichloroethyl
Me
H
S
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


51-24
2,2,2-trichloroethyl
Me
H
S
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


51-25
2,2,2-trichloroethyl
Me
H
O
H
H
Br
H
heptafluoroisopropyl
H
OCF3


51-26
2,2,2-trichloroethyl
Me
H
O
H
H
I
H
heptafluoroisopropyl
H
CF3


51-27
2,2,2-trichloroethyl
Me
H
O
H
H
CF3
H
heptafluoroisopropyl
H
CF3


51-28
2,2,2-trichloroethyl
Me
H
O
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


51-29
2,2,2-trichloroethyl
Me
H
O
H
H
Br
H
nonafluoro-2-butyl
H
CF3


51-30
2,2,2-trichloroethyl
Me
H
O
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


51-31
2,2,2-trichloroethyl
Me
H
NH
H
H
I
H
heptafluoroisopropyl
H
OCF3


51-32
2,2,2-trichloroethyl
Me
H
NH
H
H
Cl
H
heptafluoroisopropyl
H
CF3


51-33
2,2,2-trichloroethyl
Me
H
NH
H
H
CF3
H
heptafluoroisopropyl
H
CF3


51-34
2,2,2-trichloroethyl
Me
H
NH
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


51-35
2,2,2-trichloroethyl
Me
H
NH
H
H
I
H
nonafluoro-2-butyl
H
CF3


51-36
2,2,2-trichloroethyl
Me
H
NH
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


51-37
2,2,2-trichloroethyl
H
Me
S
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


51-38
2,2,2-trichloroethyl
H
Me
S
H
H
Br
H
heptafluoroisopropyl
H
CF3


51-39
2,2,2-trichloroethyl
H
Me
S
H
H
CF3
H
heptafluoroisopropyl
H
CF3


51-40
2,2,2-trichloroethyl
H
Me
S
H
H
I
H
nonafluoro-2-butyl
H
OCF3


51-41
2,2,2-trichloroethyl
H
Me
S
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


51-42
2,2,2-trichloroethyl
H
Me
S
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


51-43
2,2,2-trichloroethyl
H
Me
O
H
H
Br
H
heptafluoroisopropyl
H
OCF3


51-44
2,2,2-trichloroethyl
H
Me
O
H
H
I
H
heptafluoroisopropyl
H
CF3


51-45
2,2,2-trichloroethyl
H
Me
O
H
H
CF3
H
heptafluoroisopropyl
H
CF3


51-46
2,2,2-trichloroethyl
H
Me
O
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


51-47
2,2,2-trichloroethyl
H
Me
O
H
H
Br
H
nonafluoro-2-butyl
H
CF3


51-48
2,2,2-trichloroethyl
H
Me
O
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


51-49
2,2,2-trichloroethyl
H
Me
NH
H
H
I
H
heptafluoroisopropyl
H
OCF3


51-50
2,2,2-trichloroethyl
H
Me
NH
H
H
Cl
H
heptafluoroisopropyl
H
CF3


51-51
2,2,2-trichloroethyl
H
Me
NH
H
H
CF3
H
heptafluoroisopropyl
H
CF3


51-52
2,2,2-trichloroethyl
H
Me
NH
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


51-53
2,2,2-trichloroethyl
H
Me
NH
H
H
I
H
nonafluoro-2-butyl
H
CF3


51-54
2,2,2-trichloroethyl
H
Me
NH
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


51-55
2,2,2-trichloroethyl
Me
Me
S
H
H
Cl
H
heptafluoroisopropyl
H
OCF3


51-56
2,2,2-trichloroethyl
Me
Me
S
H
H
Br
H
heptafluoroisopropyl
H
CF3


51-57
2,2,2-trichloroethyl
Me
Me
S
H
H
CF3
H
heptafluoroisopropyl
H
CF3


51-58
2,2,2-trichloroethyl
Me
Me
S
H
H
I
H
nonafluoro-2-butyl
H
OCF3


51-59
2,2,2-trichloroethyl
Me
Me
S
H
H
Cl
H
nonafluoro-2-butyl
H
CF3


51-60
2,2,2-trichloroethyl
Me
Me
S
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


51-61
2,2,2-trichloroethyl
Me
Me
O
H
H
Br
H
heptafluoroisopropyl
H
OCF3


51-62
2,2,2-trichloroethyl
Me
Me
O
H
H
I
H
heptafluoroisopropyl
H
CF3


51-63
2,2,2-trichloroethyl
Me
Me
O
H
H
CF3
H
heptafluoroisopropyl
H
CF3


51-64
2,2,2-trichloroethyl
Me
Me
O
H
H
Cl
H
nonafluoro-2-butyl
H
OCF3


51-65
2,2,2-trichloroethyl
Me
Me
O
H
H
Br
H
nonafluoro-2-butyl
H
CF3


51-66
2,2,2-trichloroethyl
Me
Me
O
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


51-67
2,2,2-trichloroethyl
Me
Me
NH
H
H
I
H
heptafluoroisopropyl
H
OCF3


51-68
2,2,2-trichloroethyl
Me
Me
NH
H
H
Cl
H
heptafluoroisopropyl
H
CF3


51-69
2,2,2-trichloroethyl
Me
Me
NH
H
H
CF3
H
heptafluoroisopropyl
H
CF3


51-70
2,2,2-trichloroethyl
Me
Me
NH
H
H
Br
H
nonafluoro-2-butyl
H
OCF3


51-71
2,2,2-trichloroethyl
Me
Me
NH
H
H
I
H
nonafluoro-2-butyl
H
CF3


51-72
2,2,2-trichloroethyl
Me
Me
NH
H
H
CF3
H
nonafluoro-2-butyl
H
CF3


51-73
2,2,2-trichloroethyl
Me
H
S
H
H
Cl
F
heptafluoroisopropyl
H
OCF3


51-74
2,2,2-trichloroethyl
H
H
S
H
H
Br
H
heptafluoroisopropyl
F
CF3


51-75
2,2,2-trichloroethyl
H
H
S
H
H
CF3
Cl
heptafluoroisopropyl
H
CF3


51-76
2,2,2-trichloroethyl
H
H
S
H
H
I
H
nonafluoro-2-butyl
Cl
OCF3


51-77
2,2,2-trichloroethyl
H
H
S
H
H
Cl
Br
nonafluoro-2-butyl
H
CF3


51-78
2,2,2-trichloroethyl
H
H
S
H
H
CF3
H
nonafluoro-2-butyl
Br
CF3


51-79
2,2,2-trichloroethyl
H
H
O
H
H
Br
I
heptafluoroisopropyl
H
OCF3


51-80
2,2,2-trichloroethyl
Me
H
O
H
H
I
H
heptafluoroisopropyl
I
CF3


51-81
2,2,2-trichloroethyl
H
H
O
H
H
CF3
Me
heptafluoroisopropyl
H
CF3


51-82
2,2,2-trichloroethyl
H
H
O
H
H
Cl
H
nonafluoro-2-butyl
Me
OCF3


51-83
2,2,2-trichloroethyl
H
H
O
H
H
Br
F
nonafluoro-2-butyl
F
CF3


51-84
2,2,2-trichloroethyl
H
H
O
H
H
CF3
Cl
nonafluoro-2-butyl
Cl
CF3


51-85
2,2,2-trichloroethyl
H
H
NH
H
H
I
Br
heptafluoroisopropyl
Br
OCF3


51-86
2,2,2-trichloroethyl
H
H
NH
H
H
Cl
I
heptafluoroisopropyl
I
CF3


51-87
2,2,2-trichloroethyl
Me
H
NH
H
H
CF3
F
heptafluoroisopropyl
Me
CF3


51-88
2,2,2-trichloroethyl
H
H
NH
H
H
Br
Cl
nonafluoro-2-butyl
Me
OCF3


51-89
2,2,2-trichloroethyl
H
H
NH
H
H
I
Br
nonafluoro-2-butyl
Me
CF3


51-90
2,2,2-trichloroethyl
H
H
NH
H
H
CF3
I
nonafluoro-2-butyl
Me
CF3









Hereinbelow, Table 52 shows the physical properties of the representative compounds of the amide derivative of the present invention. The 1H-NMR chemical shill values shown therein are based on tetramethylsilane as an internal standard substance unless specified otherwise.










TABLE 52





com-



pound


number

1H-NMR (CDCl3, ppm)








1-470
δ 7.55-7.68 (3H, m), 7.80-7.99 (6H, m), 8.58 (1H, s), 8.61 (1H, s), 9.12 (1H, d, J = 1.5 Hz).


1-491
δ 7.34-7.91 (4H, m), 8.00 (1H, s), 8.08 (2H, dd, J = 1.9, 6.8 Hz), 8.00 (1H, s), 8.49 (1H, s), 8.59 (1H, s),



9.04 (1H, s).


1-506
δ 7.48 (1H, dd, J = 4.9, 7.81 Hz), 7.83-7.90 (3H, m), 8.00 (1H, s), 8.31 (1H, dd, J = 1.9, 7.8 Hz), 8.34 (1H, s),



8.61 (1H, dd, J = 1.9, 4.9 Hz), 9.09 (1H, s), 9.10 (1H, s).


1-513
δ 7.54 (1H, d, J = 7.8 Hz), 7.83-7.90 (3H, m), 8.00 (1H, s), 8.21 (1H, dd, J = 2.4, 8.3 Hz), 8.31 (1H, s),



8.51 (1H, s), 9.00 (1H, s), 9.01 (1H, d, J = 7.8 Hz).


1-627
δ 7.56-7.59 (3H, m), 7.64-7.66 (1H, m), 7.80-7.87 (2H, m), 7.94-7.97 (2H, m), 8.16 (1H, s), 8.46 (1H, s),



8.57 (1H, s), 9.16 (1H, s).


1-1925
δ 7.52-7.59 (2H, m), 7.65-7.71 (2H, m), 7.93-7.95 (2H, m), 8.00-8.02 (2H, m), 8.12-8.16 (2H, m), 8.52 (1H, d, J = 11.2 Hz).


1-1968
δ 7.54 (1H, d J = 8.8 Hz), 7.72 (1H, d J = 8.8 Hz), 7.93 (1H, s), 8.09 (1H, s), 8.17-8.18 (2H, m), 8.27 (1H, dd, J = 2.4,



8.8 Hz), 8.38 (1H, d J = 10.8 Hz), 8.98 (1H, d, J = 2.4 Hz).


2-491
δ 3.81 (3H, broad-s), 7.52-7.84 (8H, m), 7.89 (1H, s), 8.00 (1H, s).


2-513
δ 3.58 (3H, s), 7.34-7.36 (1H, m), 7.81-8.00 (8H, m).


2-518
δ 3.59 (3H, s), 7.69 (1H, broad-s), 7.81-8.01 (7H, m), 8.50 (1H, broad-s).


6-38
δ 7.51-7.62 (4H, m), 7.75-8.00 (8H, m), 8.32 (1H, s).


6-39
δ 7.22 (1H, dd, J = 8.0, 12.4 Hz), 7.32-7.36 (1H, m), 7.51-7.55 (2H, m), 7.78 (1H, d, J = 7.6 Hz),



7.86-7.90 (3H, m), 8.11 (1H, s), 8.17-8.18 (1H, m), 8.35 (1H, s), 8.62-8.67 (1H, m).


6-45
δ 7.57-7.59 (1H, m), 7.65-7.69 (1H, m), 7.77-7.79 (1H, m), 7.89-7.9 (5H, m), 8.14-8.29 (4H, m).


6-46
δ 7.55-7.59 (1H, m), 7.77-8.07 (10H, m), 8.27 (1H, s).


6-47
δ 7.01-7.05 (2H, m), 7.44-7.56 (2H, m), 7.78-7.86 (4H, m), 8.03 (1H, s), 8.11 (1H, s), 8.33 (1H, s).


6-57
δ 7.28-7.32 (1H, m), 7.45-7.67 (4H, m), 7.76-8.02 (5H, m), 8.30 (1H, s).


6-60
δ 7.50-7.60 (2H, m), 7.78-8.02 (6H, m), 8.19-8.27 (2H, m), 8.91 (1H, s).


6-71
δ 7.51-7.62 (4H, m), 7.78-7.80 (1H, d, J = 8.0 Hz), 7.90-7.92 (3H, m), 8.06-8.09 (4H, m), 8.34 (1H, s).


6-72
δ 7.22-7.25 (1H, m), 7.35 (1H, t, J = 8.0 Hz), 7.55-7.60 (2H, m), 7.80 (1H, d, J = 8.0 Hz), 7.92 (1H, d, J = 8.0 Hz),



8.01 (1H, s), 8.10 (2H, s), 8.20 (1H, t, J = 8.0 Hz), 8.37 (1H, s), 8.65 (1H, d, J = 16.8 Hz).


6-78
δ 7.58 (1H, t, J = 7.8 Hz), 7.68 (1H, t, J = 7.8), 7.80 (1H, d, J = 8.0 Hz), 7.87 (1H, d, 8.0 Hz), 7.95 (1H, d, J = 8.0 Hz),



8.00 (1H, s), 8.09 (2H, s), 8.15 (1H, d, J = 8.0 Hz), 8.23 (1H, s), 8.26 (1H, s), 8.30 (1H, s).


6-79
δ 7.58 (1H, t, J = 8.2 Hz), 7.79-7.83 (3H, m), 7.97 (2H, s), 8.01 (2H, d, J = 8.0 Hz), 8.09 (2H, s), 8.18 (1H, s),



8.29 (1H, s).


6-80
δ 7.05 (2H, t, J = 8.2 Hz), 7.48 (1H, t, J = 6.6 Hz), 7.56 (1H, t, J = 7.8 Hz), 7.81 (1H, d, J = 8.0 Hz), 7.89-7.91 (2H,



m), 7.98 (1H, s), 8.10 (2H, s), 8.33 (1H, s).


6-90
δ 7.43-7.46 (1H, m), 7.59 (1H, t, J = 7.2 Hz), 7.82 (1H, d, J = 7.2 Hz), 7.93 (2H, d, J = 9.6 Hz), 8.10 (2H, s),



8.24 (1H, d, J = 6.4 Hz), 8.33 (1H, s), 8.44 (1H, s), 8.56 (1H, s).


6-93
δ 7.51 (1H, d, J = 8.4 Hz), 7.59 (1H, t, J = 7.6 Hz), 7.81 (1H, d, J = 7.6 Hz), 7.94 (2H, s), 8.10-8.11 (3H, m),



8.20 (1H, d, J = 8.0 Hz), 8.28 (1H, s), 8.91 (1H, s).


6-111
(DMSO-d6) δ 7.50-7.60 (4H, m), 7.70-7.73 (1H, m), 7.93-8.00 (3H, m), 8.04-8.08 (1H, m), 8.34-8.36 (2H, m),



10.48 (1H, s), 10.60 (1H, s).


6-147
(DMSO-d6) δ 7.55-7.61 (2H, m), 7.74 (1H, d, J = 7.9 Hz), 7.94-7.97 (2H, m), 8.10 (1H, dd, J = 2.0, 7.6 Hz),



8.27 (1H, s), 8.34 (1H, s), 8.54 (1H, dd, J = 2.0, 4.9 Hz), 10.65 (1H, s), 10.89 (1H, s).


6-268
δ 7.50-7.61 (4H, m), 7.70 (1H, d, J = 7.8 Hz), 7.85-7.92 (4H, m), 7.96-8.01 (2H, m), 8.14 (1H, s), 8.24 (1H, t,



J = 2.0 Hz).


6-269
δ 7.22-7.25 (1H, m), 7.36 (1H, t, J = 8.0 Hz), 7.56-7.57 (2H, m), 7.75 (1H, d, J = 8.0 Hz), 7.90-8.00 (2H, m),



8.07 (1H, s), 8.17-8.20 (2H, m), 8.33 (1H, s), 8.65 (1H, d, J = 16.4 Hz).


6-270
δ 7.25 (1H, t, J = 8.0 Hz), 7.43-7.53 (2H, m), 7.77-7.81 (4H, m), 7.85 (1H, d, J = 8.0 Hz), 7.91 (1H, s), 8.13 (1H,



s), 8.19 (1H, d, J = 8.0 Hz), 8.24 (1H, s).


6-271
δ 7.09-7.22 (2H, m), 7.55 (1H, t, J = 7.8 Hz), 7.71 (1H, d, J = 8.0 Hz), 7.89-7.93 (4H, m), 8.03 (2H, d, J = 8.0 Hz),



8.14 (1H, s), 8.23 (1H, s).


6-272
δ 7.40-7.50 (4H, m), 7.56 (1H, t, J = 8.0 Hz), 7.80 (2H, t, J = 8.4 Hz), 7.87 (2H, s), 7.91 (1H, d, J = 7.9 Hz),



8.09 (1H, s), 8.32 (1H, s).


6-288
δ 7.54-7.55 (1H, m), 7.65-7.66 (1H, m), 7.72 (1H, d, J = 7.8 Hz), 7.85 (1H, d, J = 7.8 Hz), 7.91 (1H, s),



7.95-7.98 (2H, m), 8.13-8.23 (4H, m), 8.36 (1H, s).


6-289
δ 7.55-7.56 (1H, m), 7.71 (1H, d, J = 7.8 Hz), 7.80 (2H, d, J = 8.3 Hz), 7.91-7.96 (3H, m), 7.99 (2H, d, J = 8.3 Hz),



8.20 (1H, s), 8.21-8.22 (2H, m).


6-290
δ 7.01-7.05 (2H, m), 7.42-7.44 (1H, m), 7.55 (1H, t, J = 8.0 Hz), 7.75 (1H, d, J = 8.0 Hz), 7.90-7.95 (3H, m),



8.01 (1H, s), 8.14 (1H, s), 8.26 (1H, s).


6-293
δ 7.14 (1H, t, J = 8.0 Hz), 7.22-7.29 (2H, m), 7.54 (1H, t, J = 7.8 Hz), 7.74 (1H, d, J = 7.8 Hz), 7.84-7.88 (3H, m),



8.11 (1H, s), 8.15 (1H, s), 8.25 (1H, s).


6-300
δ 7.06-7.59 (2H, m), 7.62 (1H, dd, J = 1.5, 7.8 Hz), 7.81 (1H, d, J = 7.8 Hz), 7.92 (1H, s), 8.08-8.16 (4H, m),



9.35-9.40 (1H, m), 9.51 (1H, broad-s).


6-304
δ 7.44 (1H, dd, J = 4.9, 7.8 Hz), 7.58 (1H, t, J = 7.8 Hz), 7.75 (1H, d, J = 7.8 Hz), 7.81 (1H, s), 7.92-7.96 (2H,



m), 8.15 (1H, s), 8.22-8.26 (2H, m), 8.38 (1H, s), 8.55 (1H, dd, J = 2.0, 4.9 Hz).


6-306
δ 7.42-7.45 (1H, m), 7.58 (1H, t, J = 7.8 Hz), 7.75 (1H, d, J = 7.8 Hz), 7.88 (1H, broad-s), 7.93-7.95 (2H, m),



8.15 (1H, broad-s), 8.23 (1H, dd, J = 2.0, 7.8 Hz), 8.24 (1H, s), 8.39 (1H, broad-s), 8.55 (1H, dd, J = 2.0, 4.8 Hz).


6-311
δ 7.45-7.52 (1H, m), 7.74 (1H, d, J = 8.0 Hz), 7.92-7.96 (1H, m), 8.00 (1H, s), 8.14 (1H, s), 8.22-8.23 (3H, m),



8.29 (1H, d, J = 8.0 Hz), 8.91 (1H, s), 9.07 (1H, s).


6-346
δ 7.50-7.62 (4H, m), 7.71-7.73 (1H, m), 7.89-7.93 (4H, m), 8.02-8.04 (2H, m), 8.13 (1H, s), 8.27 (1H, s).


6-347
δ 7.19-7.25 (1H, m), 7.33-7.37 (1H, m), 7.52-7.59 (2H, m), 7.73-7.75 (1H, m), 7.89-7.91 (2H, m),



8.09-8.21 (3H, m), 8.31 (1H, s), 8.65 (1H, s).


6-348
δ 7.30-7.31 (1H, m), 7.48-7.74 (5H, m), 7.91-7.92 (2H, m), 8.02 (1H, s), 8.07 (1H, s), 8.13 (1H, s),



8.25 (1H, s).


6-349
δ 7.17-7.21 (2H, m), 7.51-7.55 (1H, m), 7.70-7.72 (1H, m), 7.88-7.93 (4H, m), 8.04 (1H, s), 8.11-8.23 (2H,



m), 8.23 (1H, s).


6-366
δ 7.53-7.55 (1H, m), 7.62-7.72 (2H, m), 7.84-7.94 (3H, m), 8.09-8.16 (3H, m), 8.22-8.24 (2H, m), 8.40 (1H,



s).


6-367
δ 7.54-7.58 (1H, m), 7.72-7.74 (1H, m), 7.80-7.83 (2H, m), 7.91-7.94 (2H, m), 8.00-8.07 (2H, m), 8.13 (1H,



s), 8.18 (1H, s), 8.23 (1H, s), 8.24 (1H, s).


6-368
δ 7.01-7.06 (2H, m), 7.44-7.57 (3H, m), 7.74-7.76 (1H, m), 7.86-7.91 (2H, m), 8.07 (1H, s), 8.13-8.14 (1H,



m), 8.28 (1H, s).


6-382
δ 7.43-7.46 (1H, m), 7.56-7.60 (1H, m), 7.76-7.78 (1H, m), 7.90-7.91 (2H, m), 8.02 (1H, s), 8.14 (1H, s),



8.25 (2H, s), 8.43 (1H, s), 8.54-8.56 (1H, m).


6-389
δ 7.30-7.60 (2H, m), 7.74-7.76 (1H, m), 7.91-7.98 (3H, m), 8.07 (1H, s), 8.14 (1H, s), 8.19-8.23 (2H, m),



8.90 (1H, s).


6-424
δ 7.51-7.62 (4H, m), 7.73 (1H, d, J = 8.3 Hz), 7.89-7.94 (4H, m), 8.01 (1H, s), 8.10 (1H, s), 8.27 (1H, t, J = 1.5 Hz),



8.35 (1H, s).


6-425
δ 7.20-7.25 (1H, m), 7.34-7.37 (1H, m), 7.54-7.58 (2H, m), 7.75 (1H, d, J = 7.6 Hz), 7.88-7.95 (2H, m),



8.18-8.22 (2H, m), 8.33-8.34 (2H, m), 8.66 (1H, d, J = 16.4 Hz).


6-426
δ 7.28-7.30 (1H, m), 7.46-7.66 (5H, m), 7.71-7.94 (2H, m), 8.11-8.24 (3H, m), 8.34 (1H, s).


6-427
δ 7.18-7.22 (2H, m), 7.52-7.57 (1H, m), 7.73 (1H, d, J = 7.6 Hz), 7.89-8.03 (5H, m), 8.22-8.25 (2H, m),



8.35 (1H, s).


6-428
δ 7.42-7.50 (4H, m), 7.56 (1H, t, J = 8.0 Hz), 7.75 (1H, d, J = 8.0 Hz), 7.81 (1H, d, J = 7.8 Hz), 7.95-7.96 (2H, m),



8.09 (1H, s), 8.28 (1H, s), 8.36 (1H, s).


6-444
δ 7.56 (1H, t, J = 7.8 Hz), 7.66 (1H, t, J = 7.8 Hz), 7.73 (1H, t, J = 7.8 Hz), 7.86 (1H, dd, J = 1.5, 7.8 Hz),



7.93-7.96 (2H, m), 8.07 (1H, s), 8.14-8.16 (1H, m), 8.22-8.26 (3H, m), 8.34 (1H, s).


6-445
δ 7.57 (1H, t, J = 7.8 Hz), 7.74 (1H, d, J = 7.8 Hz), 7.81-7.83 (2H, m), 7.95 (1H, s), 7.97-8.04 (4H, m),



8.12 (1H, broad-s), 8.23 (1H, t, J = 2.0 Hz), 8.35 (1H, broad-s).


6-446
δ 7.01-7.05 (2H, m), 7.43-7.57 (2H, m), 7.75-7.77 (1H, m), 7.88-7.94 (3H, m), 8.13 (1H, s), 8.27 (1H, s),



8.35 (1H, s).


6-448
δ 7.39-7.41 (1H, m), 7.51-7.58 (2H, m), 7.74-7.78 (2H, m), 7.90-7.95 (2H, m), 8.04 (1H, s), 8.15 (1H, s),



8.26 (1H, s), 8.35 (1H, s).


6-449
δ 7.12-7.36 (3H, m), 7.52-7.58 (1H, m), 7.75-7.95 (4H, m), 8.21-8.35 (3H, m).


6-450
6.82-6.86 (1H, m), 7.00-7.01 (1H, m), 7.15 (1H, t, J = 7.8 Hz), 7.56 (1H, t, J = 8.2 Hz), 7.74 (1H, d, J = 8.1 Hz),



7.84 (1H, t, J = 8.8 Hz), 7.90-7.91 (1H, m), 7.95 (1H, s), 8.04 (1H, s), 8.42 (1H, s).


6-451
δ 7.23-7.69 (8H, m), 7.85 (1H, s), 8.04 (1H, s), 8.42 (1H, s).


6-452
δ 7.44 (1H, dd, J = 2.0, 8.3 Hz), 7.59 (1H, t, J = 8.3 Hz), 7.66 (1H, d, J = 8.3 Hz), 7.70 (1H, d, J = 2.0 Hz),



7.75 (1H, d, J = 8.3 Hz), 7.86 (2H, broad-s), 7.95 (2H, broad-s), 8.24 (1H, broad-s), 8.37 (1H, broad-s).


6-453
δ 7.15 (1H, dt, J = 2.4, 8.3 Hz), 7.40 (1H, dd, J = 2.4, 8.3 Hz), 7.60 (1H, t, J = 8.3 Hz), 7.68-7.74 (2H, m),



7.95-8.02 (4H, m), 8.24 (1H, s), 8.35 (1H, s).


6-454
δ 7.59 (1H, t, J = 7.8 Hz), 7.75 (1H, d, J = 7.8 Hz), 7.93 (1H, s), 7.95-7.99 (3H, m), 8.10 (1H, broad-s),



8.23-8.26 (2H, m), 8.36 (2H, d, J = 1.9 Hz).


6-460
δ 7.43-7.46 (1H, m), 7.58 (1H, t, J = 7.8 Hz), 7.77 (1H, d, J = 7.8 Hz), 7.91-7.95 (2H, m), 8.01 (1H, s),



8.24 (1H, dd, J = 2.0, 7.8 Hz), 8.28 (1H, s), 8.36 (1H, s), 8.41 (1H, s), 8.54-8.56 (1H, m).


6-461
δ 7.45 (1H, dd, J = 4.9, 7.3 Hz), 7.59 (1H, t, J = 7.8 Hz), 7.77 (1H, d, J = 7.8 Hz), 7.92-7.99 (3H, m),



8.24-8.29 (2H, m), 8.36-8.39 (2H, m), 8.55 (1H, dd, J = 2.0, 4.9 Hz).


6-467
δ 7.45-7.60 (2H, m), 7.74 (1H, d, J = 8.0 Hz), 7.95-7.97 (2H, m), 8.03 (1H, s), 8.12 (1H, s), 8.19-8.35 (2H,



m), 8.35 (1H, s), 8.90 (1H, s).


6-502
δ 7.51-7.62 (4H, m), 7.73 (1H, d, J = 7.6 Hz), 7.89-7.95 (4H, m), 8.01 (2H, d, J = 14.4 Hz), 8.27 (1H, s), 8.34 (1H,



s).


6-503
δ 7.20-7.23 (1H, m), 7.34 (1H, t, J = 7.8 Hz), 7.54-7.60 (2H, m), 7.74 (1H, d, J = 7.8 Hz), 7.94 (2H, s), 8.05 (1H,



s), 8.19 (1H, t, J = 7.8 Hz), 8.33 (2H, d, J = 12.0 Hz), 8.65 (1H, d, J = 16.0 Hz).


6-504
δ 7.47-7.69 (5H, m), 7.73 (1H, d, J = 7.8 Hz), 7.93 (2H, s), 8.05 (2H, d, J = 11.0 Hz), 8.25 (1H, s), 8.34 (1H, s).


6-505
δ 7.20 (2H, t, J = 7.8 Hz), 7.56 (1H, t, J = 8.0 Hz), 7.73 (1H, d, J = 8.2 Hz), 7.91-7.94 (5H, m), 8.02 (1H, s),



8.24 (1H, s), 8.35 (1H, s).


6-522
δ 7.68-7.75 (2H, m), 7.86 (1H, d, J = 8.2 Hz), 7.93-7.96 (2H, m), 8.08 (1H, s), 8.14 (1H, d, J = 8.0 Hz), 8.24 (2H,



d, J = 8.2 Hz), 8.28 (1H, s), 8.33 (1H, s), 8.62 (1H, s).


6-523
δ 7.57 (1H, t, J = 7.8 Hz), 7.82 (2H, d, J = 8.0 Hz), 7.93-8.02 (6H, m), 8.14 (1H, s), 8.23 (1H, s), 8.34 (1H, s).


6-524
δ 7.05 (2H, t, J = 8.0 Hz), 7.43-7.50 (1H, m), 7.56 (1H, t, J = 8.0 Hz), 7.75 (1H, d, J = 7.8 Hz), 7.86 (1H, s),



7.92 (2H, d, J = 8.2 Hz), 8.00 (1H, s), 8.27 (1H, s), 8.34 (1H, s).


6-538
δ 7.45 (1H, t, J = 7.6 Hz), 7.59 (2H, s), 7.70 (1H, d, J = 4.0 Hz), 7.93 (2H, d, J = 7.6 Hz), 7.98 (1H, s), 8.28 (1H, s),



8.34 (2H, d, J = 7.6 Hz), 8.41 (1H, s).


6-545
δ 7.56-7.60 (1H, m), 7.75 (1H, d, J = 8.0 Hz), 7.92-8.00 (4H, m), 8.09 (1H, s), 8.19-8.23 (2H, m), 8.35 (1H, s),



8.90 (1H, s).


6-804
δ 7.50-7.62 (4H, m), 7.68-7.70 (1H, m), 7.85-7.91 (3H, m), 8.10 (1H, s), 8.16-8.22 (4H, m).


6-824
δ 7.55-7.59 (2H, m), 7.66-7.76 (2H, m), 7.86-7.92 (2H, m), 7.99-8.08 (2H, m), 8.13-8.22 (2H, m),



8.39-8.43 (2H, m).


6-825
δ 7.55-7.59 (2H, m), 7.66-7.70 (2H, m), 7.72-7.73 (2H, m), 7.86-7.92 (2H, m), 7.99-8.22 (3H, m),



8.40-8.42 (1H, m).


6-840
δ 7.42-7.45 (1H, m), 7.55-7.59 (1H, t, J = 7.8 Hz), 7.71-7.30 (1H, d, J = 7.8 Hz), 7.88-7.91 (1H, m), 8.00 (1H,



s), 8.20-8.24 (4H, m), 8.41 (1H, s), 8.54-8.55 (1H, m).


6-1104
δ 7.40 (1H, t, J = 7.8 Hz), 7.53-7.64 (3H, m), 7.89 (2H, s), 7.90-7.95 (3H, m), 8.11-8.14 (2H, m),



8.69-8.70 (1H, m).


6-1105
δ 7.22-7.26 (1H, m), 7.35-7.41 (2H, m), 7.58 (1H, d, J = 8.0 Hz), 7.88-7.92 (3H, m), 8.15-8.25 (2H, m),



8.74-8.75 (2H, m).


6-1106
δ 7.35-7.34 (1H, m), 7.417.42 (1H, m), 7.53-7.54 (1H, m), 7.67-7.68 (2H, m), 7.89-7.90 (3H, m),



8.09-8.10 (2H, m), 8.66-8.68 (1H, m).


6-1107
δ 7.21-7.26 (2H, m), 7.39-7.41 (1H, m), 7.89-7.96 (4H, m), 8.05-8.13 (3H, m), 8.70-8.72 (1H, m).


6-1124
δ 7.42-7.43 (1H, m), 7.70-7.72 (1H, m), 7.89-7.92 (4H, m), 8.09-8.17 (3H, m), 8.22 (1H, s), 8.62-8.63 (1H,



m).


6-1125
δ 7.42-7.44 (1H, m), 7.84-7.94 (5H, m), 8.02-8.11 (4H, m), 8.63-8.64 (1H, m).


6-1126
δ 7.05-7.09 (2H, m), 7.38-7.42 (1H, m), 7.49-7.50 (1H, m), 7.88-7.99 (4H, m), 8.09-8.12 (1H, m),



8.71-8.72 (1H, m).


6-1140
δ 7.40-7.49 (2H, m), 7.89 (2H, s), 7.94-7.96 (1H, m), 8.13 (1H, d, J = 12.7 Hz), 8.32-8.34 (1H, m),



8.57-8.59 (1H, m), 8.67-8.71 (1H, m), 8.75 (1H, broad-s).


6-1147
δ 7.39-7.44 (1H, m), 7.52-7.55 (1H, m), 7.89 (1H, s), 7.96-7.98 (1H, m), 8.05-8.11 (3H, m), 8.21-8.23 (1H,



m), 8.61-8.62 (1H, m), 8.93 (1H, s).


6-1182
δ 7.37-7.41 (1H, m), 7.53-7.64 (3H, m), 7.87-7.94 (5H, m), 8.11-8.14 (2H, m), 8.67-8.71 (1H, m).


6-1183
δ 7.35-7.41 (2H, m), 7.58-7.61 (1H, m), 7.86-7.92 (3H, m), 8.17-8.25 (2H, m), 8.61 (1H, s), 8.74 (1H, t, J = 7.8 Hz),



8.90-8.93 (1H, m).


6-1184
δ 7.33 (1H, t, J = 8.0 Hz), 7.40 (1H, t, J = 7.8 Hz), 7.50-7.56 (1H, m), 7.64-7.69 (2H, m), 7.88 (2H, s), 7.92 (1H, t,



J = 7.8 Hz), 8.09-8.12 (2H, m), 8.63 (1H, t, J = 8.2 Hz).


6-1185
δ 7.22 (2H, t, J = 7.8 Hz), 7.29-7.30 (1H, m), 7.40 (1H, t, J = 8.0 Hz), 7.88 (2H, s), 7.90-7.97 (2H, m), 8.05 (1H, s),



8.10-8.13 (1H, m), 8.64 (1H, t, J = 7.8 Hz).


6-1202
δ 7.42-7.44 (1H, m), 7.68-7.72 (1H, m), 7.88-7.94 (4H, m), 8.10-8.23 (4H, m), 8.60-8.65 (1H, m).


6-1203
δ 7.39-7.44 (1H, m), 7.84-7.88 (4H, m), 7.92-7.95 (1H, m), 8.02-8.13 (4H, m), 8.61-8.65 (1H, m).


6-1204
δ 7.05 (2H, t, J = 8.0 Hz), 7.40 (1H, t, J = 8.0 Hz), 7.48-7.52 (1H, m), 7.87 (2H, s), 7.92 (1H, t, J = 8.0 Hz),



8.01 (1H, s), 8.11-8.14 (1H, m), 8.68 (1H, t, J = 7.4 Hz).


6-1218
δ 7.40-7.49 (2H, m), 7.95 (2H, s), 7.94 (1H, t, J = 7.8 Hz), 8.12-8.16 (1H, m), 8.34 (1H, d, J = 8.0 Hz), 8.58 (1H,



s), 8.70 (1H, t, J = 7.8 Hz), 8.77 (1H, s).


6-1225
δ 7.42 (1H, t, J = 8.2 Hz), 7.53 (1H, d, J = 8.0 Hz), 7.88 (2H, s), 7.94 (1H, t, J = 7.0 Hz), 8.06 (1H, s),



8.09-8.12 (1H, m), 8.20-8.23 (1H, m), 8.60 (1H, t, J = 8.0 Hz), 8.93 (1H, s).


6-1260
δ 7.39 (1H, t, J = 7.8 Hz), 7.52-7.57 (4H, m), 7.60-7.63 (2H, m), 7.93-7.94 (4H, m), 8.70 (1H, t, J = 6.3 Hz).


6-1261
δ 7.22-7.28 (1H, m), 7.35-7.42 (2H, m), 7.59-7.61 (1H, m), 7.94-7.95 (1H, m), 8.12 (2H, s), 8.15-8.25 (2H,



m), 8.78 (1H, t, J = 1.5 Hz), 9.00 (1H, d, J = 7.8 Hz).


6-1262
δ 7.30-7.33 (1H, m), 7.40-7.44 (1H, m), 7.52-7.55 (2H, m), 7.64-7.70 (3H, m), 7.95-7.96 (1H, m),



8.09-8.13 (2H, m), 8.67-8.68 (1H, m).


6-1263
δ 7.20-7.26 (3H, m), 7.38-7.42 (1H, m), 7.91-7.98 (3H, m), 8.07-8.12 (3H, m), 8.63-8.67 (1H, m).


6-1280
δ 7.41-7.45 (1H, m), 7.68-7.72 (1H, m), 7.90-7.99 (2H, m), 8.08-8.25 (5H, m), 8.22-8.24 (1H, m),



8.56-8.65 (1H, m).


6-1281
δ 7.41-7.50 (1H, m), 7.86-7.87 (2H, m), 7.95-7.98 (1H, m), 8.03-8.13 (6H, m), 8.65-8.67 (1H, m).


6-1282
δ 7.06 (2H, t, J = 8.3 Hz), 7.38-7.42 (1H, m), 7.47-7.52 (1H, m), 7.93-7.97 (1H, m), 8.01 (1H, s),



8.11-8.13 (3H, m), 8.68-8.72 (1H, m).


6-1296
δ 7.41-7.52 (2H, m), 7.96-8.00 (1H, m), 8.12-8.14 (3H, m), 8.33-8.35 (1H, m), 8.57-8.59 (1H, m),



8.68-8.76 (2H, m).


6-1303
δ 7.41-7.45 (1H, m), 7.51-7.54 (1H, m), 7.96-7.99 (1H, m), 8.06-8.24 (5H, m), 8.61 (1H, m), 8.94 (1H, m).


6-1338
δ 7.38-7.42 (1H, m), 7.52-7.64 (3H, m), 7.90-7.94 (3H, m), 8.11-8.15 (4H, m), 8.67-8.71 (1H, m).


6-1339
δ 7.35-7.42 (2H, m), 7.60 (1H, d, J = 8.0 Hz), 7.94 (1H, t, J = 8.0 Hz), 8.11 (2H, s), 8.17-8.25 (2H, m), 8.62 (1H,



s), 8.74 (1H, t, J = 7.4 Hz), 8.92 (1H, d, J = 16.4 Hz).


6-1340
δ 7.28-7.35 (2H, m), 7.40 (1H, t, J = 8.0 Hz), 7.51-7.56 (1H, m), 7.64-7.70 (2H, m), 7.94 (1H, t, J = 8.0 Hz),



8.10 (2H, s), 8.14 (1H, s), 8.65 (1H, t, J = 8.0 Hz).


6-1341
δ 7.20-7.25 (2H, m), 7.40 (1H, t, J = 8.0 Hz), 7.92-7.97 (3H, m), 8.09 (1H, d, J = 8.0 Hz), 8.11 (2H, s), 8.14 (1H,



s), 8.64 (1H, t, J = 8.0 Hz).


6-1358
δ 7.41-7.45 (1H, m), 7.68-7.72 (1H, m), 7.89-7.98 (2H, m), 8.10-8.23 (6H, m), 8.60-8.64 (1H, m).


6-1359
δ 7.41-7.45 (1H, m), 7.83-7.89 (2H, m), 7.94-7.99 (1H, m), 8.03-8.14 (6H, m), 8.62-8.66 (1H, m).


6-1360
δ 7.05 (1H, t, J = 8.8 Hz), 7.41-7.46 (1H, m), 7.52 (1H, t, J = 7.8 Hz), 7.95 (1H, t, J = 7.8 Hz), 8.03 (1H, s),



8.10 (2H, s), 8.15 (1H, s), 8.61 (1H, s), 8.70 (1H, t, J = 8.0 Hz).


6-1374
δ 7.41-7.49 (2H, m), 8.00 (1H, t, J = 8.0 Hz), 8.11 (2H, s), 8.16 (1H, s), 8.34 (1H, d, J = 7.2 Hz), 8.58 (1H, d, J = 2.0 Hz),



8.70 (1H, t, J = 7.8 Hz), 8.78 (1H, s).


6-1381
δ 7.43 (1H, t, J = 8.0 Hz), 7.53 (1H, d, J = 8.0 Hz), 7.97 (1H, t, J = 7.8 Hz), 8.11-8.12 (3H, m), 8.14 (1H, s),



8.22 (1H, d, J = 8.0 Hz), 8.57 (1H, t, J = 8.0 Hz), 8.94 (1H, s).


6-1574
δ 7.37-7.41 (1H, m), 7.53-7.64 (3H, m), 7.86-7.94 (4H, m), 8.13-8.22 (3H, m), 8.67-8.72 (1H, m).


6-1575
δ 7.22-7.27 (1H, m), 7.35-7.41 (2H, m), 7.57-7.60 (1H, m), 7.88-7.93 (2H, m), 8.16 (1H, s), 8.20-8.25 (2H,



m), 8.74-8.75 (1H, m), 8.77-9.00 (1H, m).


6-1576
δ 7.27-7.37 (2H, m), 7.48-7.53 (1H, m), 7.72-7.80 (3H, m), 7.92 (1H, s), 8.15 (1H, s), 8.27-8.31 (1H, m),



9.16 (1H, s), 9.35 (1H, d, J = 7.3 Hz).


6-1577
δ 7.20-7.23 (3H, m), 7.24-7.26 (1H, m), 7.39-7.40 (3H, m), 7.86-7.97 (1H, m), 8.06 (1H, d, J = 2.4 Hz),



8.16-8.20 (1H, m), 8.62-8.67 (1H, m).


6-1594
δ 7.41-7.42 (1H, m), 7.70-7.71 (1H, m), 7.93-8.89 (3H, m), 8.12-8.24 (5H, m), 8.60-8.61 (1H, m).


6-1595
δ 7.41 (1H, t, J = 7.8 Hz), 7.84-7.87 (2H, m), 7.90-7.94 (2H, m), 8.03-8.05 (2H, m), 8.12-8.18 (3H, m),



8.62-8.66 (1H, m).


6-1596
δ 7.00-7.09 (2H, m), 7.40-7.41 (1H, m), 7.46-7.53 (1H, m), 7.89-7.92 (2H, m), 8.00 (1H, s),



8.16-8.19 (2H, m), 8.71-8.72 (1H, m).


6-1610
δ 7.42-7.49 (2H, m), 7.93-7.94 (2H, m), 8.15-8.21 (2H, m), 8.31-8.34 (1H, m), 8.57-8.59 (1H, m),



8.63-8.69 (2H, m).


6-1617
δ 7.31-7.38 (1H, m), 7.49 (1H, d, J = 8.3 Hz), 7.82-7.86 (1H, m), 7.92 (1H, s), 8.15 (1H, s), 8.19-8.23 (1H,



m), 8.30 (1H, dd, J = 2.4, 8.3 Hz), 9.04-9.09 (2H, m), 9.53 (1H, s).


6-1652
δ 7.40 (1H, t, J = 7.8 Hz), 7.53-7.64 (3H, m), 7.86-7.94 (4H, m), 8.13-8.20 (3H, m), 8.71-8.72 (1H, m).


6-1653
δ 7.22-7.25 (1H, m), 7.35-7.41 (2H, m), 7.57-7.60 (1H, m), 7.88-7.92 (2H, m), 8.15 (1H, s), 8.20-8.29 (2H,



m), 8.71-8.75 (1H, m), 8.89-8.93 (1H, m).


6-1654
δ 7.32-7.34 (1H, m), 7.38-7.42 (1H, m), 7.50-7.56 (1H, m), 7.63-7.70 (2H, m), 7.88-7.91 (2H, m),



8.09-8.20 (3H, m), 8.63-8.68 (1H, m).


6-1655
δ 7.21-7.30 (2H, m), 7.37-7.41 (1H, m), 7.86-7.97 (4H, m), 8.06-8.21 (3H, m), 8.63-8.67 (1H, m).


6-1672
δ 7.37-7.41 (1H, m), 7.67-7.71 (1H, m), 7.88-7.91 (3H, m), 8.15-8.18 (2H, m), 8.24-8.28 (3H, m),



8.52-8.56 (1H, m).


6-1673
δ 7.39-7.44 (1H, m), 7.85-7.93 (4H, m), 8.03-8.05 (2H, m), 8.13-8.18 (3H, m), 8.61-8.65 (1H, m).


6-1674
δ 7.04-7.09 (2H, m), 7.38-7.42 (1H, m), 7.47-7.52 (1H, m), 7.89-7.93 (2H, m), 8.00 (1H, s), 8.14-8.20 (2H,



m), 8.69-8.73 (1H, m).


6-1688
δ 7.42 (1H, t, J = 7.8 Hz), 7.47 (1H, dd, J = 4.9, 7.8 Hz), 7.92-7.96 (2H, m), 8.14 (1H, s), 8.19 (1H, d, J = 12.7 Hz),



8.33 (1H, dd, J = 2.0, 7.8 Hz), 8.58 (1H, dd, J = 2.0, 4.9 Hz), 8.70-8.71 (1H, m), 8.74 (1H, s).


6-1695
δ 7.39-7.43 (1H, m), 7.52-7.54 (1H, m), 7.92-7.95 (2H, m), 8.08-8.09 (1H, m), 8.15 (1H, s), 8.17-8.23 (2H,



m), 8.57-8.93 (1H, m), 8.94 (1H, s).


6-1730
δ 7.40 (1H, t, J = 7.8 Hz), 7.53-7.64 (3H, m), 7.87-7.95 (4H, m), 8.14 (1H, s), 8.22 (1H, d, J = 12.7 Hz),



8.37 (1H, s), 8.71-8.72 (1H, m).


6-1731
δ 7.22-7.25 (1H, m), 7.35-7.37 (2H, m), 7.58-7.60 (1H, m), 7.90 (1H, t, J = 8.6 Hz), 7.96 (1H, s), 8.22 (1H, t, J = 8.8 Hz),



8.29-8.32 (1H, d, J = 12.4 Hz), 8.37 (1H, s), 8.73 (1H, m), 8.94 (1H, s).


6-1732
δ 7.32-7.33 (1H, m), 7.37 (1H, t, J = 8.0 Hz), 7.52-7.54 (1H, m), 7.64-7.70 (2H, m), 7.90 (1H, t, J = 6.4 Hz),



7.96 (1H, s), 8.10 (1H, s), 8.23 (1H, d, J = 12.0 Hz), 8.37 (1H, s), 8.65 (1H, t, J = 8.0 Hz).


6-1733
δ 7.19-7.25 (2H, m), 7.35 (1H, t, J = 7.8 Hz), 7.87-7.97 (4H, m), 8.08 (1H, s), 8.25 (1H, d, J = 12.0 Hz), 8.37 (1H,



s), 8.65 (1H, t, J = 8.0 Hz).


6-1734
δ 7.43-7.52 (5H, m), 7.87-7.95 (3H, m), 8.22 (1H, d, J = 10.0 Hz), 8.35 (1H, d, J = 8.2 Hz), 8.74 (1H, t, J = 8.4 Hz).


6-1750
δ 7.40 (1H, t, J = 8.2 Hz), 7.68 (1H, t, J = 8.0 Hz), 7.88-7.95 (2H, m), 8.12 (1H, s), 8.16 (1H, d, J = 8.0 Hz),



8.23-8.25 (2H, m), 8.30-8.33 (1H, m), 8.36 (1H, s), 8.53 (1H, t, J = 7.4 Hz).


6-1751
δ 7.44 (1H, t, J = 8.0 Hz), 7.86 (2H, d, J = 8.0 Hz), 7.91-7.96 (2H, m), 8.03 (2H, d, J = 7.6 Hz), 8.13-8.22 (2H, m),



8.37 (1H, s), 8.64 (1H, t, J = 8.6 Hz).


6-1752
δ 7.04-7.11 (2H, m), 7.38-7.53 (2H, m), 7.90-7.95 (2H, m), 8.01 (1H, s), 8.22 (1H, d, J = 12.8 Hz), 8.37 (1H, s),



8.69-8.73 (1H, m).


6-1754
δ 7.39-7.44 (2H, m), 7.54 (1H, s), 7.85 (1H, d, J = 8.0 Hz), 7.90-7.95 (2H, m), 8.22 (1H, d, J = 12.0 Hz), 8.68 (1H,



s), 8.70 (1H, s), 8.69 (1H, t, J = 7.8 Hz).


6-1755
δ 7.16-7.19 (1H, m), 7.40 (1H, t, J = 8.0 Hz), 7.92-7.95 (2H, m), 8.07 (2H, t, J = 4.8 Hz), 8.24 (1H, d, J = 12.8 Hz),



8.37 (1H, s), 8.42 (1H, s), 8.70 (1H, t, J = 8.0 Hz).


6-1766
δ 7.41-7.49 (2H, m), 7.93-7.97 (2H, m), 8.22 (1H, d, J = 13.2 Hz), 8.33 (1H, dd, J = 2.0, 7.3 Hz), 8.37 (1H, s),



8.58 (1H, dd, J = 2.0, 4.9 Hz), 8.70-8.73 (2H, m).


6-1773
δ 7.40 (1H, t, J = 8.2 Hz), 7.52 (1H, d, J = 8.0 Hz), 7.91-7.96 (2H, m), 8.12-8.28 (3H, m), 8.37 (1H, s), 8.57 (1H,



s), 8.94 (1H, s).


6-1808
δ 7.38-7.42 (1H, m), 7.53-7.64 (3H, m), 7.87-7.94 (4H, m), 8.14 (1H, s), 8.23-8.26 (1H, m), 8.36 (1H, s),



8.68-8.71 (1H, m).


6-1809
δ 7.22-7.25 (2H, m), 7.38 (1H, t, J = 8.0 Hz), 7.58-7.61 (1H, m), 7.89-7.94 (2H, m), 8.23 (1H, t, J = 6.3 Hz),



8.29 (1H, d, J = 13.2 Hz), 8.36 (1H, s), 8.74 (1H, t, J = 6.3 Hz), 8.93-8.94 (1H, m).


6-1810
δ 7.30-7.33 (2H, m), 7.40 (1H, t, J = 7.8 Hz), 7.51-7.56 (1H, m), 7.64-7.70 (2H, m), 7.88-7.94 (1H, m), 8.10 (1H,



s), 8.23 (1H, d, J = 12.2 Hz), 8.36 (1H, s), 8.67 (1H, t, J = 7.8 Hz).


6-1811
δ 7.39 (1H, t, J = 8.3 Hz), 7.86-7.97 (3H, m), 8.08 (2H, s), 8.25 (1H, d, J = 12.2 Hz), 8.36 (2H, s), 8.65 (2H, t, J = 6.3 Hz).


6-1828
δ 7.30-7.33 (2H, m), 7.41 (1H, t, J = 7.6 Hz), 7.68-7.73 (1H, m), 7.89-7.94 (2H, m), 8.16 (1H, d, J = 7.6 Hz),



8.23-8.27 (1H, m), 8.41 (1H, s), 8.63-8.64 (2H, m).


6-1829
δ 7.29-7.31 (1H, m), 7.42 (1H, t, J = 8.0 Hz), 7.90-7.94 (2H, m), 8.04 (2H, d, J = 4.4 Hz), 8.15 (1H, s), 8.23 (1H, d,



J = 12.0 Hz), 8.36 (1H, s), 8.60-8.66 (2H, m).


6-1830
δ 7.06 (1H, t, J = 8.3 Hz), 7.41 (1H, t, J = 7.8 Hz), 7.67-7.69 (1H, m), 7.90-7.93 (2H, m), 8.03 (1H, s), 8.25 (1H, d,



J = 12.7 Hz), 8.35 (1H, s), 8.61 (1H, s), 8.70 (1H, t, J = 7.8 Hz).


6-1851
δ 7.42 (1H, t, J = 8.0 Hz), 7.53 (1H, d, J = 7.9 Hz), 7.92-7.94 (2H, m), 8.09 (1H, s), 8.21-8.24 (2H, m), 8.36 (1H,



s), 8.59 (1H, t, J = 8.0 Hz), 8.94 (1H, s).


6-2110
δ 7.36-7.40 (1H, m), 7.53-7.64 (3H, m), 7.84-7.97 (1H, m), 7.92-7.94 (2H, m), 8.04-8.07 (1H, m),



8.08-8.13 (1H, m), 8.20 (2H, s), 8.68-8.72 (1H, m).


6-3348
δ 7.29-7.34 (1H, m), 7.53-7.65 (3H, m), 7.80-7.84 (1H, m), 7.90-7.92 (3H, m), 8.14 (1H, broad-s), 8.20 (1H, d,



J = 2.9 Hz), 8.25 (1H, broad-s), 9.10 (1H, dd, J = 1.9, 7.3 Hz).


6-3384
δ 7.32-7.36 (1H, m), 7.45-7.48 (1H, m), 7.83-7.87 (1H, m), 7.93 (1H, broad-s), 8.10 (1H, broad-s), 8.15 (1H,



broad-s), 8.30 (1H, dd, J = 1.5, 7.3 Hz), 8.57-8.79 (1H, m), 8.78 (1H, broad-s), 9.09 (1H, dd, J = 2.4, 7.3 Hz).


6-5902
(DMSO-d6) δ 7.39 (1H, t, J = 7.8 Hz), 7.52-7.64 (4H, m), 7.81 (1H, t, J = 6.8 Hz), 7.95 (1H, s), 7.98-8.01 (3H,



m), 10.29 (1H, s), 10.68 (1H, s).


6-5903
δ 7.50-7.67 (5H, m), 7.79 (1H, d, J = 8.0 Hz), 7.92 (1H, d, J = 8.0 Hz), 8.01 (2H, d, J = 8.0 Hz), 8.10 (2H, s),



8.31 (1H, s).


6-5904
δ 7.19-7.23 (1H, m), 7.28-7.31 (1H, m), 7.58 (1H, t, J = 8.2 Hz), 7.78 (1H, d, J = 8.0 Hz), 7.91-7.94 (3H, m),



8.01 (2H, d, J = 8.0 Hz), 8.30 (2H, s), 8.61 (1H, s).


6-5905
δ 7.26 (1H, s), 7.43-7.46 (1H, m), 7.56-7.60 (1H, m), 7.80-7.94 (5H, m), 8.22-8.56 (4H, m).


6-5906
δ 7.18-7.12 (2H, m), 7.53-7.57 (1H, m), 7.76 (1H, d, J = 7.6 Hz), 7.86-8.28 (7H, m), 8.28 (1H, s).


6-5907
δ 7.39 (1H, t, J = 7.8 Hz), 7.52-7.64 (4H, m), 7.85-7.94 (4H, m), 8.06 (1H, d, J = 12.2 Hz), 8.14 (1H, broad-s),



8.67-8.71 (1H, m).


6-5908
δ 7.39-7.49 (2H, m), 7.59 (1H, s), 7.88-7.94 (2H, m), 8.07 (1H, d, J = 12.2 Hz), 8.31-8.33 (1H, m),



8.57-8.58 (1H, m), 8.60-8.70 (1H, m), 8.74 (1H, broad-s).


6-5909
δ 7.42 (1H, t, J = 7.8 Hz), 7.59 (1H, s), 7.85-7.92 (4H, m), 7.99 (1H, broad-s), 8.02-8.05 (2H, m), 8.10 (1H,



broad-s), 8.61-8.67 (1H, m).


6-5910
δ 7.39 (1H, t, J = 8.3 Hz), 7.53-7.64 (3H, m), 7.88-7.94 (4H, m), 8.13 (1H, broad-s), 8.19 (1H, broad-s),



8.24 (1H, d, J = 13.2 Hz), 8.70-8.72 (1H, m).


6-5911
δ 7.41 (1H, t, J = 8.3 Hz), 7.84-7.87 (3H, m), 7.91-7.95 (1H, m), 8.03-8.05 (2H, m), 8.10 (1H, broad-s),



8.17-8.20 (2H, m), 8.63-8.67 (1H, m).


6-5912
δ 3.10 (3H, s), 7.59 (1H, t, J = 7.8 Hz), 7.76 (1H, d, J = 7.8 hz), 7.77-8.00 (5H, m), 8.03 (1H, s), 8.19 (1H, s),



8.24 (1H, s), 8.36 (1H, s).


6-5913
δ 7.51-7.62 (4H, m), 7.72 (1H, dd, J = 1.5, 7.8 Hz), 7.89-8.00 (6H, m), 8.14 (1H, s), 8.27 (1H, t, J = 2.0 Hz).


6-5914
δ 7.44 (1H, dd, J = 4.9, 7.8 Hz), 7.56-7.60 (1H, m), 7.76 (1H, d, J = 7.8 Hz), 7.92 (3H, broad-s), 8.14 (1H, s),



8.22-8.27 (1H, m), 8.27 (1H, s), 8.41 (1H, s), 8.55 (1H, dd, J = 2.0, 4.4 Hz).


7-38
δ 3.57 (3H, s), 7.21-7.24 (1H, m), 7.32-7.34 (4H, m), 7.40-7.44 (2H, m), 7.59 (1H, s), 7.71 (1H, d, J = 8.0 Hz),



7.84 (3H, s).


7-39
δ 3.54 (3H, s), 7.06-7.19 (1H, m), 7.28-7.34 (2H, m), 7.43-7.48 (2H, m), 7.57 (1H, s), 7.69 (1H, s), 7.75 (1H, d, J = 8.0 Hz),



7.90 (1H, d, J = 8.0 Hz), 8.06 (2H, s).


7-45
δ 3.57 (3H, s), 7.29-7.30 (2H, m), 7.48 (1H, t, J = 8.0 Hz), 7.59 (1H, s), 7.68-7.71 (3H, m), 7.77 (1H, d, J = 7.8 Hz),



7.85 (2H, s), 8.24 (1H, s).


7-46
δ 3.57 (3H, s), 7.41-7.45 (3H, m), 7.52 (2H, s), 7.55 (1H, d, J = 8.0 Hz), 7.69 (1H, s), 7.74 (1H, d, J = 7.8 Hz),



7.86 (2H, s), 8.62 (1H, s).


7-47
δ 3.56 (3H, s), 6.97-7.05 (3H, m), 7.17-7.19 (1H, m), 7.43-7.50 (3H, m), 7.73 (1H, s), 7.85 (2H, s).


7-57
δ 3.57 (3H, s), 7.15 (1H, t, J = 6.0 Hz), 7.41 (2H, s), 7.50 (1H, s), 7.52 (1H, s), 7.60 (1H, d, J = 6.4 Hz), 7.73 (1H,



s), 7.85 (2H, s), 8.27 (1H, s).


7-60
3.57 (3H, s), 7.30 (1H, d, J = 8.0 Hz), 7.47 (1H, t, J = 8.0 Hz), 7.61 (1H, s), 7.76 (2H, s), 7.78-7.81 (1H, m),



7.85 (2H, s), 8.11 (1H, s), 8.24 (1H, s).


7-71
δ 3.56 (3H, s), 7.20-7.25 (1H, m), 7.33-7.38 (3H, m), 7.43-7.47 (3H, m), 7.56 (1H, s), 7.74 (1H, d, J = 6.8 Hz),



8.06-8.10 (3H, m).


7-72
δ 3.55 (3H, s), 7.06-7.10 (1H, m), 7.30-7.36 (2H, m), 7.43-7.48 (2H, m), 7.57 (1H, s), 7.68 (1H, s), 7.78 (1H, d, J = 8.0 Hz),



7.90 (1H, d, J = 8.0 Hz), 8.07 (2H, s).


7-78
δ 3.57 (3H, s), 7.29-7.64 (2H, m), 7.70 (1H, s), 7.79 (1H, d, J = 8.0 Hz), 7.86 (1H, d, J = 8.0 Hz), 7.95 (1H, t, J = 8.0 Hz),



8.08 (2H, s), 8.33 (1H, d, J = 8.0 Hz), 8.40 (1H, s), 8.71 (1H, s).


7-79
δ 3.58 (3H, s), 7.42-7.53 (3H, m), 7.60-7.66 (1H, m), 7.77 (1H, d, J = 8.0 Hz), 7.89 (1H, t, J = 8.0 Hz), 8.08 (2H,



s), 8.21 (1H, d, J = 8.0 Hz), 8.70 (2H, s).


7-80
δ 3.56 (3H, s), 7.02 (1H, t, J = 8.0 Hz), 7.42-7.44 (1H, m), 7.55 (1H, t, J = 8.0 Hz), 7.75 (1H, d, J = 8.0 Hz),



7.90-7.95 (3H, m), 8.01 (1H, s), 8.14 (1H, s), 8.26 (1H, s).


7-90
δ 3.59 (3H, s), 7.59 (1H, s), 7.60 (1H, d, J = 6.0 Hz), 7.80-7.83 (1H, m), 8.08 (2H, s), 8.26-8.30 (2H, m), 8.53 (1H,



d, J = 4.0 Hz), 8.69 (2H, s).


7-93
δ 3.58 (3H, s), 7.34-7.52 (3H, m), 7.63 (1H, d, J = 16.0 Hz), 7.69 (1H, d, J = 8.0 Hz), 7.80 (1H, d, J = 8.0 Hz),



7.85 (1H, t, J = 8.0 Hz), 8.25 (1H, s), 8.29 (1H, d, J = 8.0 Hz), 8.69 (1H, s).


7-132
δ 3.57 (3H, s), 7.26-7.28 (1H, m), 7.41-7.46 (3H, m), 7.52-7.54 (3H, m), 7.63 (1H, s), 7.68 (1H, d, J = 7.8 Hz),



7.87 (1H, s), 7.98 (1H, s).


7-147
δ 3.58 (3H, s), 7.14 (1H, dd, J = 4.9, 7.8 Hz), 7.41-7.42 (2H, m), 7.52 (1H, s), 7.59 (1H, dd, J = 1.5, 7.8 Hz),



7.67 (2H, broad-s), 7.87 (1H, s), 7.97 (1H, s), 8.26 (1H, dd, J = 1.5, 4.9 Hz).


7-268
δ 3.49 (3H, s), 7.12-7.16 (2H, m), 7.21-7.28 (4H, m), 7.35 (1H, t, J = 7.8 Hz), 7.64 (1H, s), 7.70 (1H, dd, J = 1.5,



8.8 Hz), 7.86 (1H, s), 8.07 (1H, d, J = 1.5 Hz), 8.29 (1H, s).


7-269
δ 3.54 (3H, s), 6.80-6.81 (1H, m), 7.70-7.08 (1H, m), 7.25-7.26 (1H, m), 7.39-7.41 (4H, m), 7.52-7.53 (1H,



m), 7.70-7.71 (1H, m), 7.90 (1H, s), 8.12 (1H, s).


7-270
δ 3.55 (3H, s), 6.97-6.99 (1H, m), 7.04-7.06 (2H, m), 7.15-7.21 (1H, m), 7.32-7.34 (1H, m), 7.44 (1H, t, J = 7.8 Hz),



7.58-7.59 (2H, m), 7.70 (1H, d, J = 7.8 Hz), 7.90 (1H, s), 8.12 (1H, s).


7-271
δ 3.55 (3H, s), 6.88-6.92 (2H, m), 7.30-7.34 (3H, m), 7.43 (1H, t, J = 7.8 Hz), 7.57-7.58 (2H, m),



7.67-7.69 (1H, m), 7.90-7.91 (1H, m), 8.13-8.14 (1H, m).


7-285
δ 3.59 (3H, s), 7.34-7.52 (3H, m), 7.65-7.73 (4H, m), 7.90 (1H, s), 8.13-8.16 (3H, m).


7-286
δ 3.59 (3H, s), 7.29-7.30 (1H, m), 7.42-7.52 (4H, m), 7.63 (1H, s), 7.69 (1H, d, J = 7.8 Hz), 7.91 (1H, s),



8.08-8.13 (3H, m).


7-288
δ 3.57 (3H, s), 7.15-7.37 (2H, m), 7.47-7.48 (1H, m), 7.52-7.62 (5H, m), 7.72 (1H, d, J = 7.8 Hz), 7.91 (1H,



s), 8.14 (1H, s).


7-289
δ 3.57 (3H, s), 7.26-7.29 (1H, m), 7.40-7.46 (3H, m), 7.52 (2H, d, J = 8.3 Hz), 7.58-7.61 (2H, m), 7.70 (1H,



d, J = 7.8 Hz), 7.92 (1H, s), 8.14 (1H, s).


7-290
δ 3.55 (3H, s), 6.70-6.74 (2H, m), 7.14-7.19 (1H, m), 7.43-7.44 (2H, m), 7.52 (1H, s), 7.67 (1H, s),



7.74-7.77 (1H, m), 7.91 (1H, s), 8.13 (1H, s).


7-299
δ 3.58 (3H, s), 7.33 (1H, d, J = 6.8 Hz), 7.52 (1H, t, J = 7.8 Hz), 7.64-7.65 (2H, m), 7.75-7.79 (3H, m),



7.83 (1H, s), 7.92 (1H, s), 8.14 (1H, s).


7-300
δ 3.56 (3H, broad-s), 7.14 (1H, broad-d, J = 8.3 Hz), 7.33-7.53 (4H, m), 7.59-7.60 (2H, m), 7.71-7.72 (1H,



m), 7.92 (1H, s), 8.14 (1H, s).


7-301
δ 3.57 (3H, s), 7.33-7.59 (4H, m), 7.60 (1H, s), 7.64 (1H, s), 7.68-7.70 (2H, m), 7.92 (1H, s), 8.15 (1H, s).


7-303
δ 3.56 (3H, s), 7.17-7.12 (1H, m), 7.39-7.45 (2H, m), 7.55 (2H, s), 7.69 (1H, d, J = 7.8 Hz), 7.90 (2H, s),



8.13-8.14 (2H, m).


7-304
δ 3.54 (3H, s), 7.10 (1H, dd, J = 4.9, 7.8 Hz), 7.35-7.40 (2H, m), 7.56 (1H, dd, J = 1.5, 7.8 Hz), 7.70 (2H, s),



7.88-7.90 (2H, m), 8.12 (1H, s), 8.22 (1H, dd, J = 1.5, 4.9 Hz).


7-305
δ 3.57 (3H, s), 7.13 (1H, dd, J = 4.9, 7.8 Hz), 7.41-7.42 (2H, m), 7.57-7.62 (2H, m), 7.67-7.69 (2H, m),



7.91 (1H, s), 8.13 (1H, s), 8.24-8.26 (1H, m).


7-311
δ 3.57 (3H, s), 7.23-7.31 (2H, m), 7.47-7.48 (1H, m), 7.66-7.73 (4H, m), 7.92 (1H, s), 8.14 (1H, s),



8.23 (1H, d, J = 1.9 Hz).


7-316
δ 3.59 (3H, s), 7.27-7.30 (1H, m), 7.48-7.49 (1H, m), 7.60-7.67 (3H, m), 7.73 (1H, d, J = 7.8 Hz), 7.85 (1H,



dd, J = 1.9, 7.8 Hz), 7.92 (1H, s), 8.15 (1H, d, J = 1.5 Hz), 8.52 (1H, s).


7-346
δ 3.54 (3H, s), 7.18-7.34 (4H, m), 7.40 (1H, t, J = 7.8 Hz), 7.57 (1H, s), 7.67-7.69 (1H, m), 7.88 (1H, s), 8.10 (1H,



s).


7-347
δ 3.53 (3H, s), 6.82 (1H, s), 7.07 (1H, s), 7.23-7.70 (7H, m), 7.89 (1H, s), 8.11 (1H, s).


7-348
δ 3.53 (3H, s), 6.96-6.99 (1H, m), 7.00-7.06 (2H, m), 7.15-7.19 (1H, m), 7.32-7.34 (1H, m), 7.42-7.46 (1H,



m), 7.60 (1H, s), 7.68-7.71 (2H, m), 7.89 (1H, s), 8.11 (1H, s).


7-349
δ 3.54 (3H, s), 6.88-6.92 (2H, m), 7.29-7.34 (3H, m), 7.41-7.44 (2H, m), 7.59 (1H, s), 7.68-7.70 (1H, m),



7.89 (1H, s), 8.11 (1H, s).


7-366
δ 3.64 (3H, s), 7.31-7.36 (2H, m), 7.44-7.48 (2H, m), 7.52-7.58 (1H, m), 7.61 (2H, s), 7.71-7.73 (2H, m),



7.89 (1H, s), 8.12 (1H, s).


7-367
δ 3.56 (3H, s), 7.22-7.31 (3H, m), 7.44-7.48 (1H, m), 7.66-7.77 (4H, m), 7.90 (1H, s), 8.12 (1H, s),



8.22 (1H, s).


7-368
δ 3.52 (3H, s), 6.67-6.72 (2H, m), 7.00 (1H, s), 7.13-7.17 (1H, m), 7.41-7.42 (2H, m), 7.72-7.89 (3H, m),



8.11 (1H, s).


7-382
δ 3.58 (3H, s), 7.13-7.16 (1H, m), 7.43-7.61 (4H, m), 7.67 (2H, s), 7.90 (1H, s), 8.13 (1H, s), 8.26-8.27 (1H,



m).


7-389
δ 3.57 (3H, s), 7.29 (1H, s), 7.40-7.46 (3H, m), 7.52-7.54 (2H, m), 7.59-7.62 (1H, m), 7.69-7.70 (1H, m),



7.90 (1H, s), 8.13 (1H, s).


7-424
δ 3.56 (3H, s), 7.19-7.37 (6H, m), 7.44-7.45 (1H, m), 7.54 (1H, s), 7.60 (1H, broad-s), 7.68 (1H, d, J = 7.8 Hz),



7.92 (1H, s), 8.31 (1H, s).


7-425
δ 3.54 (3H, broad-s), 6.82 (1H, broad-s), 7.07 (1H, broad-s), 7.23-7.30 (2H, m), 7.31-7.51 (3H, m),



7.52-7.56 (1H, m), 7.71 (1H, broad-s), 7.92 (1H, s), 8.33 (1H, s).


7-426
δ 3.56 (3H, s), 6.96-7.00 (1H, m), 7.05-7.07 (2H, m), 7.15-7.21 (1H, m), 7.34-7.36 (1H, m), 7.46-7.47 (1H,



m), 7.58-7.66 (2H, m), 7.71 (1H, d, J = 7.3 Hz), 7.93 (1H, s), 8.33 (1H, s).


7-427
δ 3.56 (3H, s), 6.88-6.92 (2H, m), 7.31-7.34 (2H, m), 7.45-7.46 (1H, m), 7.56 (1H, s), 7.62 (1H, s),



7.65 (1H, s), 7.70 (1H, d, J = 7.3 Hz), 7.93 (1H, s), 8.33 (1H, s).


7-428
δ 3.58 (3H, s), 7.00-7.24 (4H, m), 7.42-7.43 (3H, m), 7.62 (1H, s), 7.66 (1H, s), 7.94 (1H, s), 8.34 (1H, s).


7-444
δ 3.57 (3H, s), 7.33-7.37 (2H, m), 7.48-7.49 (1H, m), 7.52-7.61 (4H, m), 7.69-7.74 (2H, m), 7.93 (1H, s),



8.34 (1H, s).


7-445
δ 3.58 (3H, s), 7.30 (1H, d, J = 9.5 Hz), 7.41-7.48 (3H, m), 7.51-7.53 (3H, m), 7.59 (1H, s), 7.70 (1H, d, J = 7.9 Hz),



7.94 (1H, s), 8.34 (1H, s).


7-446
δ 3.56 (3H, s), 6.69-6.73 (2H, m), 7.14-7.18 (1H, m), 7.44-7.45 (2H, m), 7.61 (1H, s), 7.69 (1H, s),



7.75-7.77 (1H, m), 7.93 (1H, s), 8.34 (1H, s).


7-449
δ 3.51 (3H, s), 6.82-6.86 (1H, m), 6.94-6.98 (1H, m), 7.14-7.24 (1H, m), 7.28-7.29 (2H, m), 7.41 (1H, s),



7.64 (1H, s), 7.69 (1H, d, J = 5.9 Hz), 7.94 (1H, s), 8.34 (1H, s).


7-460
δ 3.59 (3H, s), 7.13 (1H, dd, J = 4.8, 7.1 Hz), 7.43-7.44 (2H, m), 7.52 (1H, s), 7.58-7.60 (1H, m), 7.67 (2H,



broad-s), 7.94 (1H, s), 8.26 (1H, dd, J = 1.6, 4.8 Hz), 8.34 (1H, s).


7-467
δ 3.58 (3H, s), 7.23 (1H, d, J = 8.3 Hz), 7.33 (1H, d, J = 7.8 Hz), 7.49-7.50 (1H, m), 7.62 (1H, s),



7.67-7.68 (2H, m), 7.73 (1H, d, J = 7.8 Hz), 7.93 (1H, s), 8.23 (1H, d, J = 2.0 Hz), 8.34 (1H, s).


7-502
δ 3.57 (3H, s), 7.20-7.26 (3H, m), 7.27-7.37 (3H, m), 7.45 (1H, t, J = 7.6 Hz), 7.56 (1H, s), 7.68 (1H, s), 7.71 (1H,



d, J = 8.0 Hz), 7.91 (1H, s), 8.31 (1H, s).


7-504
3.56 (3H, s), 6.96-7.01 (1H, m), 7.06 (2H, d, J = 7.2 Hz), 7.18 (1H, t, J = 6.8 Hz), 7.35 (1H, d, J = 8.0 Hz), 7.45 (1H,



t, J = 8.0 Hz), 7.56 (2H, s), 7.71 (1H, d, J = 8.0 Hz), 7.91 (1H, s), 8.32 (1H, s).


7-505
δ 3.57 (3H, s), 6.90 (2H, t, J = 8.8 Hz), 7.31-7.35 (3H, m), 7.45 (1H, t, J = 8.0 Hz), 7.54 (2H, d, J = 13.6 Hz),



7.69 (1H, d, J = 8.0 Hz), 7.91 (1H, s), 8.32 (1H, s).


7-522
δ 3.57 (3H, s), 7.32-7.37 (2H, m), 7.46 (1H, t, J = 8.0 Hz), 7.55 (1H, t, J = 7.6 Hz), 7.59 (2H, d, J = 8.0 Hz),



7.75 (1H, d, J = 8.0 Hz), 7.88 (1H, s), 7.92 (2H, s), 8.33 (1H, s).


7-523
δ 3.56 (3H, s), 7.41-7.47 (4H, m), 7.53 (2H, d, J = 8.2 Hz), 7.61 (1H, s), 7.71-7.72 (2H, m), 7.92 (1H, s), 8.33 (1H,



s).


7-538
δ 3.58 (3H, s), 7.14 (1H, t, J = 6.0 Hz), 7.40-7.43 (2H, m), 7.56-7.58 (2H, m), 7.68-7.69 (2H, m), 7.92 (1H, s),



8.26 (1H, s), 8.33 (1H, s).


7-804
δ 3.55 (3H, s), 7.19-7.52 (9H, m), 7.62 (1H, d, J = 7.8 Hz), 8.16 (2H, s).


7-824
δ 3.57 (3H, s), 7.33-7.75 (7H, m), 7.98-7.99 (1H, m), 8.12 (2H, s), 8.18-8.43 (1H, m).


7-825
δ 3.57 (3H, s), 7.22-7.66 (7H, m), 7.85-7.88 (1H, m), 7.97-7.99 (2H, m), 8.17-8.27 (1H, m).


7-840
δ 3.57 (3H, s), 7.13-7.26 (1H, m), 7.40-7.44 (2H, m), 7.58-7.71 (3H, m), 8.18-8.23 (4H, m).


7-948
δ 3.49 (3H, s), 7.23-7.52 (8H, m), 7.66 (2H, s), 8.00 (1H, t, J = 6.8 Hz).


7-969
δ 3.51 (3H, s), 7.45-7.46 (3H, m), 7.53-7.55 (3H, m), 7.67 (2H, s), 7.92-7.93 (1H, m), 8.05-8.06 (1H, m).


7-984
δ 3.53 (3H, s), 7.13-7.16 (1H, m), 7.20-7.24 (1H, m), 7.52-7.53 (1H, m), 7.65-7.68 (3H, m), 7.99-8.03 (2H,



m), 8.28-8.30 (1H, m).


7-1104
δ 3.51 (3H, s), 7.22-7.44 (7H, m), 7.86 (2H, s), 8.00-8.03 (2H, m).


7-1105
δ 3.52 (3H, s), 6.82 (1H, t, J = 8.8 Hz), 7.06-7.08 (1H, m), 7.18-7.24 (2H, m), 7.40-7.44 (2H, m), 7.87 (3H, s),



8.01-8.05 (1H, m).


7-1106
δ 3.50 (3H, s), 7.00-7.23 (4H, m), 7.29-7.31 (1H, m), 7.45 (1H, s), 7.87 (3H, s), 8.03-8.07 (1H, m).


7-1107
δ 3.49 (3H, s), 6.91-6.93 (2H, m), 7.28-7.44 (4H, m), 7.86 (2H, s), 8.00-8.10 (2H, m).


7-1124
δ 3.52 (3H, s), 7.30-7.34 (2H, m), 7.46-7.59 (3H, m), 7.71 (1H, broad-s), 7.87 (2H, s), 7.97-8.09 (2H, m).


7-1125
δ 3.52 (3H, s), 7.29-7.32 (1H, m), 7.45-7.52 (5H, m), 7.84 (2H, s), 7.95-8.06 (2H, m).


7-1126
δ 3.49 (3H, s), 6.72-6.76 (2H, m), 7.16-7.23 (2H, m), 7.43-7.50 (1H, m), 7.88 (2H, s), 8.02-8.06 (1H, m),



8.13-8.17 (1H, m).


7-1140
δ 3.54 (3H, s), 7.13-7.16 (1H, m), 7.21-7.26 (1H, m), 7.43-7.46 (1H, m), 7.52 (1H, broad-s), 7.65-7.69 (1H, m),



7.88 (2H, s), 8.00-8.04 (1H, m), 8.28-8.30 (1H, m).


7-1147
δ 3.52 (3H, s), 7.22-7.26 (1H, m), 7.34 (1H, t, J = 7.8 Hz), 7.46-7.52 (1H, m), 7.62-7.68 (1H, m), 7.87 (2H,



s), 7.91-7.95 (1H, m), 8.07-8.11 (1H, m), 8.34 (1H, broad-s).


7-1182
δ 3.51 (3H, s), 7.22-7.44 (7H, m), 7.85 (2H, s), 8.00-8.03 (2H, m).


7-1183
δ 3.51 (3H, s), 6.79-6.83 (1H, m), 7.05 (1H, t, J = 7.8 Hz), 7.17-7.23 (2H, m), 7.40-7.43 (2H, m), 7.85 (2H, s),



7.98-8.00 (2H, m).


7-1184
δ 3.52 (3H, s), 6.99-7.22 (4H, m), 7.28-7.30 (1H, m), 7.44-7.45 (1H, m), 7.88 (2H, s), 8.02-8.06 (2H, m).


7-1185
δ 3.49 (3H, s), 6.91-7.00 (2H, m), 7.26-7.44 (4H, m), 7.85 (2H, s), 8.01-8.10 (2H, m).


7-1202
δ 3.52 (3H, s), 7.26-7.32 (1H, m), 7.45-7.52 (5H, m), 7.86 (2H, s), 7.84-7.95 (1H, m), 8.06-8.08 (1H, m).


7-1203
δ 3.52 (3H, s), 7.26-7.32 (1H, m), 7.45-7.52 (5H, m), 7.86 (2H, s), 7.84-7.95 (1H, m), 8.06-8.08 (1H, m).


7-1204
δ 3.51 (3H, s), 7.02 (1H, t, J = 8.8 Hz), 7.39-7.44 (1H, m), 7.50 (1H, t, J = 7.4 Hz), 7.93 (1H, t, J = 7.8 Hz),



8.02 (1H, s), 8.10 (2H, s), 8.13 (1H, s), 8.68 (1H, t, J = 8.0 Hz).


7-1218
δ 3.52 (3H, s), 7.39-7.47 (1H, m), 7.96 (1H, t, J = 8.0 Hz), 8.11 (2H, s), 8.16 (1H, s), 8.33 (1H, d, J = 7.2 Hz),



8.58-8.59 (1H, m), 8.68 (1H, t, J = 7.8 Hz), 8.78 (1H, s).


7-1225
δ 3.52 (3H, s), 7.22-7.24 (1H, m), 7.32-7.36 (1H, m), 7.46-7.50 (1H, m), 7.66-7.68 (1H, m), 7.85 (2H, s),



7.93-7.96 (1H, m), 8.07-8.11 (1H, m), 8.34 (1H, broad-s).


7-1260
δ 4.09 (3H, s), 7.21-7.49 (7H, m), 7.99-8.08 (4H, m).


7-1261
δ 3.53 (3H, s), 6.79-6.83 (1H, m), 7.03-7.07 (1H, m), 7.19-7.23 (2H, m), 7.42-7.43 (2H, m), 8.01-8.10 (4H,



m).


7-1262
δ 3.51 (3H, s), 6.99-7.00 (1H, m), 7.08-7.14 (2H, m), 7.29-7.33 (2H, m), 7.46-7.47 (1H, m), 8.05-8.12 (4H,



m).


7-1263
δ 3.52 (3H, s), 6.88-6.93 (2H, m), 7.29-7.37 (3H, m), 7.46-7.48 (1H, m), 8.04-8.09 (4H, m).


7-1280
δ 3.52 (3H, s), 7.31-7.47 (2H, m), 7.49 (1H, s), 7.57 (2H, m), 7.69 (1H, s), 8.07-8.10 (4H, m).


7-1281
δ 3.53 (3H, s), 7.23-7.52 (6H, m), 7.90-8.09 (4H, m).


7-1282
δ 3.55 (3H, s), 6.72-6.76 (2H, m), 7.17-7.24 (2H, m), 7.48-7.49 (1H, m), 8.04-8.16 (4H, m).


7-1296
δ 3.55 (3H, s), 7.12-7.15 (1H, m), 7.46-7.51 (1H, broad-s), 7.67-7.69 (1H, m), 8.03-8.12 (5H, m),



8.27-8.29 (1H, m).


7-1303
δ 3.54 (3H, s), 7.20-7.23 (1H, m), 7.35-7.39 (1H, m), 7.52-7.53 (1H, m), 7.65 (1H, s), 7.97 (1H, broad-s),



8.09-8.14 (3H, m), 8.34-8.35 (1H, m).


7-1338
δ 3.52 (3H, s), 7.10-7.35 (6H, m), 7.45-7.52 (1H, m), 8.02-8.07 (4H, m).


7-1339
δ 3.53 (3H, s), 6.80 (1H, t, J = 8.0 Hz), 7.04 (1H, t, J = 8.0 Hz), 7.29-7.32 (1H, m), 7.43 (1H, t, J = 8.0 Hz),



7.68-7.71 (1H, m), 8.01-8.04 (2H, m), 8.09 (2H, s), 8.63 (1H, s).


7-1340
δ 3.56 (3H, s), 7.04-7.08 (1H, m), 7.30-7.33 (1H, m), 7.43-7.48 (2H, m), 7.57 (1H, s), 7.64 (1H, s), 7.77 (1H, d, J = 8.0 Hz),



7.90 (1H, d, J = 8.0 Hz), 8.07 (2H, s).


7-1341
δ 3.52 (3H, s), 6.91-6.92 (2H, m), 7.30 (1H, t, J = 8.0 Hz), 7.36 (2H, s), 7.47 (1H, t, J = 8.0 Hz), 8.00-8.06 (2H, m),



8.08 (2H, s).


7-1358
δ 3.53 (3H, s), 7.31-7.40 (2H, m), 7.45-7.60 (3H, m), 7.69 (1H, s), 7.99-8.11 (4H, m).


7-1359
δ 3.53 (3H, s), 7.26-7.34 (1H, m), 7.40-7.60 (5H, m), 7.83-7.95 (1H, m), 8.01-8.06 (3H, m).


7-1360
δ 3.55 (3H, s), 6.72-6.76 (2H, m), 7.22-7.24 (1H, m), 7.42-7.44 (1H, m), 7.49 (1H, t, J = 8.0 Hz), 8.05 (1H, d, J = 8.0 Hz),



8.10 (2H, s), 8.17 (1H, d, J = 8.0 Hz).


7-1374
δ 3.55 (3H, s), 7.12-7.15 (1H, m), 7.52-7.53 (2H, m), 7.68 (1H, d, J = 8.0 Hz), 8.02-8.06 (2H, m), 8.11 (2H, s),



8.28 (1H, s).


7-1381
δ 3.54 (3H, s), 7.19-7.22 (1H, m), 7.37 (1H, t, J = 8.0 Hz), 7.54 (1H, t, J = 6.0 Hz), 7.66 (1H, d, J = 6.8 Hz),



7.93-7.96 (1H, m), 8.09-8.13 (3H, m), 8.35 (1H, s).


7-1417
δ 3.49 (3H, s), 7.23-7.26 (3H, m), 7.27-7.33 (3H, m), 7.52-7.53 (1H, m), 7.85 (1H, s), 7.96-8.06 (3H, m).


7-1574
δ 3.50 (3H, s), 6.99-7.33 (6H, m), 7.43-7.45 (1H, m), 7.90 (1H, s), 7.97-8.06 (2H, m), 8.13 (1H, s).


7-1575
δ 3.52 (3H, s), 6.82-6.83 (1H, m), 7.06-7.07 (1H, m), 7.19-7.26 (2H, m), 7.39-7.46 (2H, m), 7.91 (1H, s),



7.99-8.01 (1H, m), 8.07-8.14 (2H, m).


7-1576
δ 3.50 (3H, s), 7.01-7.17 (4H, m), 7.27-7.31 (1H, m), 7.46-7.52 (1H, m), 7.91 (1H, s), 8.01-8.05 (2H, m),



8.13 (1H, s).


7-1577
δ 3.50 (3H, s), 6.90-6.94 (2H, m), 7.26-7.35 (3H, m), 7.45-7.46 (1H, m), 7.90 (1H, s), 8.00-8.07 (2H, m),



8.13 (1H, s).


7-1594
δ 3.52 (3H, s), 7.29-7.36 (2H, m), 7.50 (2H, broad-s), 7.60 (1H, broad-d, J = 6.8 Hz), 7.70 (1H, broad-s),



7.91 (1H, broad-s), 8.04-8.07 (2H, m), 8.14 (1H, s).


7-1595
δ 3.51 (3H, s), 7.29-7.31 (2H, m), 7.44-7.52 (4H, m), 7.92 (1H, s), 8.03-8.06 (2H, m), 8.14 (1H, broad-s).


7-1596
δ 3.54 (3H, s), 6.75 (2H, broad-s), 7.17-7.26 (2H, m), 7.50-7.51 (1H, m), 7.92 (1H, s), 8.01-8.05 (1H, m),



8.14-8.20 (2H, m).


7-1605
δ 3.53 (3H, s), 7.41 (1H, t, J = 7.8 Hz), 7.53-7.55 (1H, m), 7.82-7.86 (3H, m), 7.91 (1H, s), 7.99-8.01 (1H,



m), 8.10-8.14 (2H, m).


7-1606
δ 2.53 (3H, s), 7.15-7.17 (1H, m), 7.24-7.28 (1H, m), 7.39-7.41 (1H, m), 7.41-7.44 (1H, m), 7.53-7.56 (1H,



m), 7.93 (1H, s), 8.04-8.08 (2H, m), 8.15 (1H, s).


7-1608
δ 3.52 (3H, s), 7.22-7.23 (1H, m), 7.29-7.33 (1H, m), 7.48-7.52 (1H, m), 7.71-7.72 (1H, m), 7.90 (1H, s),



8.00-8.03 (2H, m), 8.13 (1H, s), 8.54-8.55 (2H, m).


7-1610
δ 3.54 (3H, s), 7.14-7.17 (2H, m), 7.45-7.70 (2H, m), 7.96 (1H, s), 8.00-8.07 (3H, m), 8.28-8.30 (1H, m).


7-1616
δ 3.52 (3H, s), 7.27-7.23 (1H, m), 7.35-7.36 (1H, m), 7.49-7.51 (1H, m), 7.68 (1H, d, J = 6.8 Hz), 7.91 (1H,



s), 8.09-8.05 (2H, m), 8.13 (1H, s), 8.30 (1H, s).


7-1617
δ 3.52 (3H, s), 7.23-7.27 (1H, m), 7.33-7.37 (1H, m), 7.47-7.51 (1H, m), 7.67-7.68 (1H, m), 7.91 (1H, s),



8.05-8.09 (1H, m), 8.13 (2H, s), 8.30 (1H, s).


7-1638
δ 3.50 (3H, s), 7.19-7.27 (2H, m), 7.32-7.33 (1H, m), 7.40-7.42 (1H, m), 7.91 (1H, s), 8.00-8.02 (1H, m),



7.09-8.11 (1H, m), 8.14 (1H, s), 8.18 (1H, s), 8.56 (1H, d, J = 8.8 Hz).


7-1639
δ 3.52 (3H, broad-s), 7.00-7.29 (3H, m), 7.44 (1H, broad-s), 7.52 (1H, s), 7.91-8.14 (3H, m), 8.51 (2H,



broad-s).


7-1645
δ 3.50 (3H, s), 7.22-7.27 (2H, m), 7.33-7.37 (1H, m), 7.43-7.47 (1H, m), 7.92 (1H, s), 8.02-8.10 (3H, m),



8.15-8.19 (2H, m).


7-1652
δ 3.50 (3H, s), 7.23-7.26 (2H, m), 7.27-7.32 (4H, m), 7.44-7.45 (1H, m), 7.88 (1H, s), 7.98 (1H, t, J = 6.8 Hz),



8.04-8.08 (1H, m), 8.11 (1H, s).


7-1672
δ 3.51 (3H, s), 7.29-7.35 (2H, m), 7.49-7.50 (2H, m), 7.60 (1H, d, J = 6.3 Hz), 7.69 (1H, s), 7.89 (1H, s),



8.03-8.06 (2H, m), 8.12 (1H, s).


7-1673
δ 3.52 (3H, s), 7.29-7.32 (1H, m), 7.44-7.52 (5H, m), 7.89 (1H, s), 8.02-8.06 (2H, m), 8.12 (1H, s).


7-1730
δ 3.51 (3H, s), 7.21-7.23 (2H, m), 7.27-7.33 (4H, m), 7.44-7.46 (1H, m), 7.92 (1H, s), 8.00 (1H, t, J = 6.3 Hz),



8.08-8.09 (1H, m), 8.33 (1H, s).


7-1731
δ 3.51 (3H, s), 6.79-6.83 (1H, m), 7.05 (1H, t, J = 7.6 Hz), 7.18-7.46 (4H, m), 7.94-8.00 (2H, m), 8.20 (1H, d, J = 12.4 Hz),



8.34 (1H, s).


7-1732
δ 3.50 (3H, s), 7.00-7.18 (4H, m), 7.27-7.31 (1H, m), 7.45-7.48 (1H, m), 7.93 (1H, s), 8.01-8.03 (1H, m),



8.12 (1H, broad-s), 8.34 (1H, s).


7-1733
δ 3.50 (3H, s), 6.91 (2H, s), 6.93-7.35 (3H, m), 7.47 (1H, t, J = 7.0 Hz), 7.93 (1H, s), 8.01-8.10 (1H, m), 8.13 (1H,



broad-s), 8.34 (1H, s).


7-1750
δ 3.52 (3H, s), 7.28-7.71 (6H, m), 7.93 (1H, s), 8.06 (1H, t, J = 8.4 Hz), 8.34 (1H, s), 8.60 (1H, s).


7-1751
δ 3.52 (3H, s), 7.32 (1H, t, J = 8.3 Hz), 7.44-7.52 (5H, m), 7.93 (1H, s), 8.04-8.07 (2H, m), 8.34 (1H, s).


7-1752
δ 3.54 (3H, s), 6.74 (2H, s), 7.16-7.24 (2H, m), 7.50 (1H, t, J = 7.4 Hz), 7.94 (1H, s), 8.01-8.05 (1H, m), 8.25 (1H,



broad-s), 8.35 (1H, s).


7-1764
δ 3.53 (3H, s), 7.20-7.21 (1H, m), 7.32 (1H, t, J = 7.8 Hz), 7.50 (1H, t, J = 7.8 Hz), 7.70-7.71 (1H, m),



7.92 (1H, s), 8.01-8.04 (2H, m), 8.33 (1H, s), 8.53-8.54 (2H, m).


7-1766
δ 3.53 (3H, s), 7.14-7.17 (1H, m), 7.23-7.25 (1H, m), 7.54-7.55 (1H, m), 7.68 (1H, d, J = 8.0 Hz), 7.95 (1H, s),



8.00 (1H, t, J = 7.0 Hz), 8.10-8.20 (1H, m), 8.28 (1H, d, J = 4.8 Hz), 8.36 (1H, s).


7-1773
δ 3.53 (3H, s), 7.19-7.40 (3H, m), 7.52-7.53 (1H, m), 7.67-7.68 (1H, m), 7.93 (2H, s), 8.07-8.09 (1H, m),



8.32 (1H, d, J = 14.4 Hz), 8.35 (1H, s).


7-1794
δ 3.51 (3H, s), 7.18-7.23 (2H, m), 7.32 (1H, t, J = 7.8 Hz), 7.43-7.46 (1H, m), 7.92 (1H, s), 7.98-8.01 (1H,



m), 8.08-8.09 (1H, m), 8.23-8.24 (1H, m), 8.32 (1H, s), 8.56-8.59 (1H, m).


7-1808
δ 3.51 (3H, s), 7.23-7.43 (6H, m), 7.44-7.60 (1H, m), 7.91 (1H, s), 7.98-8.01 (1H, m), 8.10 (1H, broad-s),



8.32 (1H, s).


7-1809
δ 3.52 (3H, s), 6.80 (1H, t, J = 8.8 Hz), 7.06 (1H, t, J = 3.6 Hz), 7.17-7.23 (2H, m), 7.39-7.44 (1H, m),



7.92-7.93 (2H, m), 7.99 (1H, t, J = 5.2 Hz), 8.16 (1H, d, J = 13.2 Hz), 8.33 (1H, s).


7-1810
δ 3.48 (3H, s), 6.99-7.16 (3H, m), 7.28-7.34 (2H, m), 7.43-7.45 (1H, m), 7.72 (1H, t, J = 8.0 Hz), 7.92 (1H, s),



8.00 (1H, t, J = 8.0 Hz), 8.33 (1H, s).


7-1811
δ 3.53 (3H, s), 6.90 (2H, t, J = 8.0 Hz), 7.28-7.40 (3H, m), 7.46 (1H, t, J = 7.2 Hz), 7.92 (1H, s), 8.02 (1H, t, J = 8.0 Hz),



8.13 (1H, d, J = 12.4 Hz), 8.33 (1H, s).


7-1828
δ 3.52 (3H, s), 7.32-7.35 (2H, m), 7.49-7.60 (3H, m), 7.69 (1H, s), 7.92 (1H, s), 8.05-8.08 (2H, m), 8.36 (1H, s).


7-1829
δ 3.53 (3H, s), 7.30-7.34 (1H, m), 7.45-7.52 (5H, m), 7.92 (1H, s), 8.04-8.07 (2H, m), 8.34 (1H, s).


7-1844
δ 3.54 (3H, s), 7.15 (1H, t, J = 5.2 Hz), 7.52-7.54 (1H, m), 7.68-7.71 (2H, m), 7.94 (1H, s), 8.00 (1H, t, J = 5.2 Hz),



8.15-8.16 (1H, m), 8.28 (1H, d, J = 4.8 Hz), 8.34 (1H, s).


7-1851
δ 3.52 (3H, s), 7.65 (1H, d, J = 6.8 Hz), 7.92 (1H, s), 8.05-8.08 (2H, m), 8.11-8.18 (3H, m), 8.26-8.31 (1H, m),



8.33 (1H, s).


7-3348
δ 3.48 (3H, s), 7.18-7.30 (6H, m), 7.45 (1H, broad-s), 7.52 (1H, broad-s), 7.74-7.76 (1H, m), 7.89 (1H, s),



8.11 (1H, s).


7-3369
δ 3.49 (3H, s), 7.18-7.22 (1H, m), 7.45-7.53 (5H, m), 7.56 (2H, broad-s), 7.92 (1H, s), 8.14 (1H, s).


7-3384
δ 3.52 (3H, s), 7.15-7.20 (2H, m), 7.45-7.85 (4H, m), 7.92 (1H, s), 8.12-8.15 (1H, m), 8.27-8.29 (1H, m).


7-5902
δ 3.51 (3H, s), 7.00-7.52 (7H, m), 7.88 (1H, d, J = 1.5 Hz), 8.01-8.06 (3H, m).


7-5903
δ 3.55 (3H, s), 7.14 (1H, dd, J = 4.8, 7.8 Hz), 7.24-7.26 (1H, m), 7.40-7.60 (1H, m), 7.66-7.68 (1H, m),



7.91 (1H, s), 8.01-8.05 (2H, m), 8.08 (1H, d, J = 1.5 Hz), 8.28 (1H, dd, J = 2.0, 4.8 Hz).


7-5904
δ 3.56 (3H, s), 7.05-7.09 (1H, m), 7.30-7.36 (2H, m), 7.43-7.48 (2H, m), 7.56 (1H, s), 7.65 (1H, s), 7.77 (1H, d, J = 8.0 Hz),



7.90 (1H, d, J = 8.0 Hz), 8.07 (2H, s).


7-5905
δ 3.57 (3H, s), 6.89 (1H, t, J = 8.0 Hz), 7.15 (1H, t, J = 8.0 Hz), 7.32-7.36 (2H, m), 7.47 (1H, t, J = 8.0 Hz),



7.53 (1H, s), 7.61 (1H, s), 7.77 (1H, d, J = 8.0 Hz), 8.09 (2H, s), 8.70 (1H, broad-s).


7-5906
δ 3.55 (3H, s), 7.00 (1H, t, J = 8.0 Hz), 7.07 (2H, d, J = 7.8 Hz), 7.16-7.22 (1H, m), 7.32 (1H, d, J = 6.8 Hz),



7.44 (1H, t, J = 8.0 Hz), 7.57 (1H, s), 7.65-7.67 (1H, m), 7.74 (1H, d, J = 8.0 Hz), 7.85 (2H, s).


7-5907
δ 3.57 (3H, s), 6.90 (2H, t, J = 7.8 Hz), 7.29-7.34 (3H, m), 7.44 (1H, t, J = 7.8 Hz), 7.49 (1H, s), 7.62 (1H, s),



7.73 (1H, d, J = 7.8 Hz), 7.85 (2H, s).


7-5908
δ 2.99 (3H, s), 3.58 (3H, s), 7.27-7.30 (1H, m), 7.43-7.44 (1H, m), 7.51 (2H, d, J = 8.3 Hz), 7.65-7.70 (3H,



m), 7.81 (2H, d, J = 8.3 Hz), 7.91 (1H, s), 8.14 (1H, s).


7-5909
δ 3.60 (3H, s), 7.33 (1H, d, J = 7.9 Hz), 7.50 (1H, t, J = 7.9 Hz), 7.63 (1H, s), 7.70 (1H, s), 7.75 (1H, d, J = 7.9 Hz),



7.94 (1H, s), 8.34 (1H, s), 8.65 (2H, s), 9.10 (1H, s).


7-5910
δ 3.53 (3H, s), 3.89 (3H, s), 7.32 (1H, t, J = 7.8 Hz), 7.48-7.49 (1H, m), 7.83-7.91 (2H, m), 8.01 (1H, t, J = 7.3 Hz),



8.10-8.14 (3H, m), 8.22-8.23 (1H, m).


7-5911
δ 3.57 (3H, s), 7.20-7.35 (6H, m), 7.41-7.45 (2H, m), 7.53 (1H, s), 7.67 (1H, d, J = 7.8 Hz), 7.89 (1H, s),



8.11 (1H, s).


7-5912
δ 3.58 (3H, s), 7.14 (1H, dd, J = 4.9, 7.8 Hz), 7.42-7.43 (2H, m), 7.55 (1H, s), 7.59 (1H, dd, J = 2.0, 7.8 Hz),



7.67-7.68 (2H, m), 7.91 (1H, s), 8.13 (1H, s), 8.26 (1H, dd, J = 2.0, 4.9 Hz).


8-268
δ 3.28 (2/3*3H, s), 3.39 (1/3*3H, s), 7.13-7.14 (1/3*1H, m), 7.15-7.17 (1/3*1H, m), 7.34 (1/3*1H, s),



7.36 (1/3*1H, s), 7.46-7.57 (12/3*1H, m), 7.74-7.90 (13/3*1H, m), 7.94 (2/3*1H, s), 8.05 (1/3*1H, s),



8.15 (2/3*1H, s), 8.24 (2/3*1H, s).


8-288
(CDCl3 + DMSO-d6) δ 3.30 (3/4*3H, s), 3.40 (1/4*3H, s), 7.10-7.15 (1/4*1H, m), 7.20-7.25 (1/4*1H, m),



7.35 (1/4*1H, s), 7.37 (1/4*1H, s), 7.50 (3/4*1H, t, J = 7.8 Hz), 7.62-7.66 (6/4*1H, m), 7.82-7.84 (5/4*1H,



m), 7.94 (1/4*1H, s), 7.95 (3/4*1H, s), 8.00 (3/4*1H, t, J = 1.5 Hz), 8.08-8.10 (4/4*1H, m), 8.17 (3/4*1H,



s), 8.18-8.19 (1/4*1H, m), 8.32-8.36 (4/4*1H, m), 8.48 (3/4*1H, t, J = 1.5 Hz), 10.00 (1/4*1H, s),



10.29 (3/4*1H, s).


8-289
δ 3.26 (2/3*3H, s), 3.38 (1/3*3H, s), 7.08-7.09 (1/3*1H, m), 7.12-7.14 (1/3*1H, m), 7.32 (2/3*1H, d, J = 7.8 Hz),



7.45-7.49 (3/3*1H, m), 7.72-7.76 (9/*13H, m), 7.83 (1/3*1H, s), 7.85-7.89 (4/3*1H, m),



7.95 (2/3*1H, s), 7.98-8.00 (4/3*1H, m), 8.04 (2/3*1H, d, J = 6.3 Hz), 8.16 (2/3*1H, s), 8.57 (2/3*1H, s).


8-304
δ 3.29 (3/5*3H, s), 3.38 (2/5*3H, s), 7.14-7.18 (4/5*1H, m), 7.37-7.41 (8/5*1H, m), 7.50-7.52 (5/5*1H,



m), 7.72 (2/5*1H, s), 7.83-7.86 (8/5*1H, m), 7.95 (3/5*1H, s), 8.05-8.07 (4/5*1H, m), 8.14-8.17 (6/5*1H,



m), 8.30 (2/5*1H, s), 8.51-8.53 (5/5*1H, m), 8.57 (3/5*1H, s).


8-804
δ 3.31 (3H, s), 7.30-7.33 (1H, m), 7.48-7.52 (3H, m), 7.56-7.60 (1H, m), 7.72-7.74 (1H, m), 7.86-7.91 (3H,



m), 8.06 (1H, s), 8.22 (2H, s).


8-824
(DMSO-d6) δ 3.32 (12/13*3H, s), 3.43 (1/13*3H, s), 7.01-7.02 (1/13*1H, m), 7.20-7.21 (1/13*1H, m),



7.28 (12/13*1H, d, J = 7.8 Hz), 7.50 (12/13*1H, t, J = 7.8 Hz), 7.60-7.61 (1/13*1H, m), 7.65 (12/13*1H, t, J = 7.8 Hz),



7.83-7.84 (13/13*1H, m), 7.85 (1/13*1H, d, J = 1.5 Hz), 7.94 (12/13*1H, d, J = 1.5 Hz),



8.10-8.12 (12/13*1H, m), 8.14 (1/13*2H, s), 8.21-8.22 (1/13*1H, m), 8.23 (12/13*2H, s), 8.32-8.35 (13/13*1H, m),



8.47-8.48 (13/13*1H, m), 10.05 (1/13*1H, s), 10.37 (12/13*1H, s).


8-840
δ 3.30 (10/11*3H, s), 3.43 (1/11*3H, s), 7.17-7.18 (1/11*1H, m), 7.19-7.20 (1/11*1H, m),



7.33-7.42 (22/11*1H, m), 7.52 (10/11*1H, t, J = 7.8 Hz), 7.71 (1/11*1H, s), 7.75 (10/11*1H, s), 7.87 (10/11*1H, d, J = 8.3 Hz),



8.12-8.13 (1/11*1H, m), 8.14 (1/11*2H, s), 8.17 (10/11*1H, dd, J = 2.0, 7.8 Hz), 8.23 (10/11*2H,



s), 8.47-8.50 (11/11*1H, m), 8.52-8.53 (11/11*1H, m).


9-270
δ 2.64 (3/4*3H, s), 3.28 (1/4*3H, s), 3.37 (1/4*3H, s), 3.56 (3/4*3H, s), 6.70-6.71 (1/4*1H, m),



6.80-6.81 (1/4*1H, m), 7.02-7.03 (4/4*1H, m), 7.16-7.26 (16/4*1H, m), 7.34-7.36 (10/4*1H, m),



7.39-7.40 (1/4*1H, m), 7.46 (3/4*1H, t, J = 7.8 Hz), 7.80 (1/4*1H, s), 7.91 (3/4*1H, s), 8.01 (1/4*1H, s),



8.11 (3/4*1H, s).


9-290
δ 2.88 (2/3*3H, s), 3.33 (1/3*3H, s), 3.37 (1/3*3H, s), 3.56 (2/3*3H, s), 6.70-6.71 (1/3*1H, m),



6.95-6.98 (2/3*1H, m), 7.10 (2/3*1H, s), 7.28-7.42 (9/3*1H, m), 7.47-7.60 (6/3*1H, m), 7.62-7.63 (4/3*1H,



m), 7.86 (1/3*1H, s), 7.93 (2/3*1H, s), 8.08 (1/3*1H, s), 8.14 (2/3*1H, s).


9-291
δ 2.82 (2/3*3H, s), 3.30 (1/3*3H, s), 3.37 (1/3*3H, s), 3.56 (2/3*3H, s), 6.75-6.76 (1/3*1H, m),



6.95 (1/3*1H, t, J = 7.8 Hz), 7.00-7.01 (1/3*1H, m), 7.06 (2/3*1H, s), 7.28-7.32 (4/3*1H, m),



7.39-7.54 (15/3*1H, m), 7.83 (1/3*1H, s), 7.93 (2/3*1H, s), 8.04 (1/3*1H, s), 8.14 (2/3*1H, s).


9-306
δ 2.89 (2/3*3H, s), 3.30 (1/3*3H, s), 3.36 (1/3*3H, s), 3.57 (2/3*3H, s), 6.96-6.97 (1/3*1H, m),



7.04-7.05 (2/3*1H, m), 7.13-7.17 (2/3*1H, m), 7.27-7.41 (10/3*1H, m), 7.60-7.63 (3/3*1H, m), 7.81 (1/3*1H,



s), 7.94 (2/3*1H, s), 8.02 (1/3*1H, s), 8.15 (2/3*1H, s), 8.24-8.25 (3/3*1H, m).


9-2164
δ 2.18-2.19 (3H, m), 3.48 (3H, s), 7.21-7.25 (4H, m), 7.32-7.40 (4H, m), 7.92 (1H, s), 8.13 (1H, s).


9-2322
δ 2.71-2.72 (3H, m), 3.47 (3H, s), 6.95-6.96 (1H, m), 7.11-7.16 (3H, m), 7.38-7.39 (2H, m), 7.95 (1H, s),



8.02 (1H, s), 8.34 (1H, s).


11-777
δ 4.88 (2H, s), 7.20-7.21 (1H, m), 7.36 (1H, t, J = 7.8 Hz), 7.84-7.87 (1H, m), 7.92 (1H, s), 8.14-8.17 (2H,



m), 8.36 (1H, broad-s).


11-835
δ 4.88 (2H, s), 7.22-7.23 (1H, m), 7.36 (1H, t, J = 7.8 Hz), 7.85-7.88 (1H, m), 7.95 (1H, s), 8.19 (1H, d, J = 13.1 Hz),



8.36-8.37 (2H, m).


12-777
δ 3.39 (3H, s), 4.74 (2H, broad-s), 7.37 (1H, t, J = 7.8 Hz), 7.52-7.56 (1H, m), 7.92 (1H, s), 8.11-8.14 (2H,



m), 8.25 (1H, d, J = 14.1 Hz).


12-835
δ 3.40 (3H, s), 4.74 (2H, broad-s), 7.37 (1H, t, J = 7.8 Hz), 7.55-7.58 (1H, m), 7.95 (1H, s), 8.12-8.13 (1H,



m), 8.28-8.31 (1H, m), 8.36 (1H, s).


12-864
δ 3.40 (3H, s), 4.74 (2H, broad-s), 7.37 (1H, t, J = 7.8 Hz), 7.52-7.58 (1H, m), 7.93 (1H, s), 8.12-8.15 (1H,



m), 8.28-8.34 (2H, m).


17-1103
δ 3.65 (3H, s), 7.28-7.41 (6H, m), 7.77 (1H, t, J = 7.8 Hz), 7.91 (1H, s), 8.00-8.02 (1H, m), 8.14 (1H, s),



9.39 (1H, s).


22-435
δ 3.63 (3H, s), 4.90 (2H, s), 7.92-7.97 (2H, m), 8.08-8.15 (3H, m), 9.72 (1H, s).


27-627
δ 3.72 (3H, s), 7.51-7.60 (5H, m), 7.90 (1H, s), 8.05 (1H, s), 8.14 (1H, s), 9.11 (1H, s).


27-628
δ 3.67 (3H, s), 6.99-7.24 (1H, m), 7.29-7.35 (1H, m), 7.52-7.59 (2H, m), 7.90 (1H, s), 8.06 (1H, s),



8.14 (1H, s), 9.08 (1H, s).


27-663
δ 3.63 (3H, s), 7.44-7.47 (1H, m), 7.80 (1H, dd, J = 2.0, 7.8 Hz), 7.90 (1H, s), 8.10 (1H, s), 8.14 (1H, s),



8.58-8.60 (1H, m), 9.04 (1H, s).


32-247
δ 3.77-3.78 (3H, m), 4.96 (2H, s), 7.90 (1H, s), 8.00 (1H, s), 8.14 (1H, s), 9.02 (1H, s).









The pest control agent including the compound of the present invention as an active ingredient can effectively control, at a low concentration thereof, any pests such as insects including various agricultural pests damaging agricultural/horticultural crops, trees, and the like, insanitary pests adversely affecting the living environment of humans such as houses and the like in various manners, stored grain pests damaging grain and the like stored in a warehouse, wood-eating pests damaging wood such as buildings and the like, and mites, crustaceans, molluscs, and nematodes which propagate and cause damage in a manner similar to that in the case of the insects.


Specific examples of the insects, the mites, the crustaceans, molluscs and nematodes which can be controlled using the compound of the present invention include lepidopteran insects such as Adoxophyes honmai, Adoxophyes orana faciata, Archips breviplicanus, Grapholita inopinata, Archips fuscocupreanus, Grapholita molesta, Choristoneura magnanima, Leguminivora glycinivorella, Olethreutes mori, Caloptilia zachrysa, Argyresthia conjugella, Spulerrina astaurota, Matsumuraeses phaseoli, Pandemis heparana, Bucculatrix pyrivorella, Lyonetia clerkella, Carposina niponensis, Lyonetia prunifoliella malinella, Caloptilia theivora, Phyllonorycter ringoniella, Phyllocnistis citrella, Acrolepiopsis sapporensis, Acrolepiopsis suzukiella, Plutella xylostella, Stathmopoda masinissa, Helcystogramma triannulella, Pectinophora gossypiella, Carposina sasakii, Chilo suppressalis, Cnaphalocrocis medinalis, Ephestia elutella, Conogethes punctiferalis, Diaphania indica, Etiella zinckenella, Glyphodes pyloalis, Scirpophaga incertulas, Hellula undalis, Ostrinia furnacalis, Ostrinia scapulalis, Parapediasia teterrella, Parnara guttata, Pieris brassicae, Pieris rapae crucivora, Papilio xuthus, Ascotis selenaria, Pseudoplusia includens, Euproctis pseudoconspersa, Lymantria dispar, Orgyia thyellina, Hyphantria cunea, Lemyra imparilis, Adris tyrannus, Aedia leucomelas, Agrotis ipsilon, Agrotis segetum, Autographa nigrisigna, Ctenoplusia agnata, Cydla pomonella, Helicoverpa armigera, Helicoverpa assulta, Helicoverpa zea, Heliothis virescens, Ostrinia nubilalis, Mamestra brassicae, Mythimna separata, Sesamia inferens, Naranga aenescens, Spodoptera eridania, Spodoptera exigua, Spodoptera frugiperda, Spodoptera littoralis, Spodoptera litura, Spodoptera depravata, Trichoplusia ni, Endopiza viteana, Manduca quinquemaculata, Manduca sexta, and the like;


Hemipteran insects such as Arboridia apicalis, Balclutha saltuella, Epiacanthus stramineus, Empoascafabae, Empoasca nipponica, Empoasca onukii, Empoasca sakaii, Macrosteles striifrons, Nephotettix cinctinceps, Psuedatomoscelis seriatus, Laodelphax striatella, Nilaparvata lugens, Sogatellafurcfera, Diaphorina citri, Psylla pyrisuga, Aleurocanthus spiniferus, Bemisia argentifolii, Bemisia tabaci, Dialeurodes citri, Trialeurodes vaporariorum, Aleurolobus taonabae, Viteus vitifolii, Lipaphis erysimi, Aphis gossypii, Aphis spiraecola, Myzus persicae, Toxoptera aurantii, Drosicha corpulenta, Icerya purchasi, Phenacoccus solani, Pulvinaria aurantii, Planococcus citri, Pseudaonidia duplex, Planococcus kuraunhiae, Pseudococcus comstocki, Comstockaspis perniciosa, Ceroplastes ceriferus, Ceroplastes rubens, Aonidiella aurantii, Fiorinia theae, Pseudaonidia paeoniae, Pseudaulacaspis pentagona, Pseudaulacaspis prunicola, Unaspis euonymi, Unaspis yanonensis, Cimex lectularius, Dolycoris baccarum, Eurydema rugosum, Eysarcoris aeneus, Eysarcoris lewisi, Eysarcoris ventralis, Glaucias subpunctatus, Halyomorpha halys, Nezara antennata, Nezara viridula, Piezodorus hybneri, Plautia crossota, Scotinophora lurida, Cletus punctiger, Leptocorisa chinensis, Riptortus clavatus, Rhopalus msculatus, Cavelerius saccharivorus, Togo hemipterus, Dysdercus cingulatus, Stephanitis pyrioides, Halticus insularis, Lygus lineolaris, Stenodema sibiricum, Stenotus rubrovittatus, Trigonotylus caelestialium, and the like;


Coleopteran insects such as Anomala cuprea, Anomala rufocuprea, Gametis jucunda, Heptophylla picea, Popillia japonica, Lepinotarsa decemlineata, Epilachna varivestis, Melanotus fortnumi, Melanotus tamsuyensis, Lasioderma serricorne, Lyctusbrunneus, Tomicus piniperda, Rhizopertha dominica, Epuraea domina, Epilachna varivestis, Epilachna vigintioctopunctata, Tenebrio molitor, Tribolium castaneum, Anoplophora malasiaca, Monochamus alternatus, Psacothea hilaris, Xylotrechus pyrrhoderus, Callosobruchus chinensis, Aulacophora femoralis, Oulema oryzae, Chaetocnema concinna, Diabrotica undecimpunctata, Diabrotica virgifera, Diabrotica barberi, Phyllotreta striolata, Psylliodes angusticollis, Rhynchites heros, Cylas formicarius, Anthonomus grandis, Echinocnemus squameus, Euscepes postfasciatus, Hypera postica, Lissohoptrus oryzophilus, Otiorhynchus sulcatus, Sitophilus granarius, Sitophilus zeamais, Sphenophorus venatus vestitus, Paederus fuscipes, and the like;


Thysanopteran insects such as Frankliniella intonsa, Thrips flavus, Frankliniella occidentalis, Heliothrips haemorrhoidalis, Scirtothrips dorsalis, Thrips palmi, Thrips tabaci, Ponticulothrips diospyrosi, and the like;


Dipterous insects such as Asphondylia yushimai, Sitodiplosis mosellana, Bactrocera cucurbitae, Bactrocera dorsalis, Ceratitis capitata, Hydrellia griseola, Drosophila suzukii, Agromyza oryzae, Chromatomyia horticola, Liriomyza bryoniae, Liriomyza chinensis, Liriomyza sativae, Liriomyza trifolii, Delia platura, Delia antique, Pegomya cunicularia, Rhagoletis pomonella, Mayetiola destructo, Musca domestica, Stomoxys calcitrans, Melophagus ovinus, Hypoderma bovis, Hypoderma lineatum, Oestrus ovis, Glossina palpalis, Glossina morsitans, Pmsimulium yezoensis, Tabanus trigonus, Telmatoscopus albipunctatus, Leptoconops nipponensis, Culex pipiens pallens, Aedes aegypti, Aedes albopicutus, Anopheles hyracanus sinesis, and the like;


Hymenopteran insects such as Apethymus kuri, Athalia rosae, Arge pagana, Neodiprion sertifer, Dryocosmus kuriphilus, Eciton burchelli, Eciton schmitti, Camponotus japonicus, Vespa mandarina, Myrmecia spp., Solenopsis spp., Monomorium pharaonis, and the like;


Orthopteran insects such as Teleogryllus emma, Gryllotalpa orientalis, Locusta migratoria, Oxya yezoensis, Schistocerca gregaria, and the like;


Collembolan insects such as Onychiurus folsomi, Onychiurus sibiricus, Bourletiella hortensis, and the like;


Dictyopteran insects such as Periplaneta fuliginosa, Periplaneta japonica, Blattella germanica, Periplaneta Americana, and the like;


Isopterous insects such as Coptotermes formosanus, Reticulitermes speratus, Odontotermes formosanus, and the like;


Isopterous insects such as Ctenocephalidae felis, Ctenocephalides canis, Echidnophaga gallinacea, Pulex irritans, Xenopsylla cheopis, and the like;


Mallophaga insects such as Menacanthus stramineus, Bovicola bovis, and the like;


Anoplura insects such as Haematopinus eurysternus, Haematopinus suis, Linognathus vituli, Solenopotes capillatus, and the like;


Tarsonemidae such as Phytonemus pallidus, Polyphagotarsonemus latus, Tarsonemus bilobatus, and the like;


Eupodidae such as Penthaleus erythrocephalus, Penthaleus major, and the like;


Tetranychidae such as Oligonychus shinkajii, Panonychus citri, Panonychus mori, Panonychus ulmi, Tetranychus kanzawai, Tetranychus urticae, and the like;


Eriophydae such as Acaphylla theavagrans, Aceria tulipae, Aculops lycopersici, Aculops pelekassi, Aculus schlechtendali, Eriophyes chibaensis, Phyllocoptruta oleivora, and the like;


Acaridae such as Rhizoglyphus robini, Tyrophagus putrescentiae, Tyrophagus similis, and the like;


Varroidae such as Varroa jacobsoni, and the like;


Ixodidae such as Boophilus microplus, Rhipicephalus sanguineus, Haemaphysalis longicornis, Haemophysalis flava, Haemophysalis campanulata, Ixodes ovatus, Ixodes persulcatus, Amblyomma spp., Dermacentor spp., and the like;


Cheyletidae such as Cheyletiella yasguri, Cheyletiella blakei, and the like;


Demodicidae such as Demodex canis, Demodex cati, and the like;


Psoroptidae such as Psoroptes ovis, and the like;


Sarcoptidae such as Sarcoptes scabiei, Notoedres cati, Knemidocoptes spp., and the like;


Crustacea such as Armadillidium vulgare, and the like;


Gastropoda such as Pomacea canaliculata, Achatina fulica, Meghimatium bilineatum, Limax Valentiana, Acusta despecta sieboldiana, Euhadra peliomphala, and the like; and


Nematoda such as Prathylenchus coffeae, Prathylenchus penetrans, Prathylenchus vulnus, Globodera rostochiensis, Heterodera glycines, Meloidogyne hapla, Meloidogyne incognita, Aphelenchoides besseyi, Bursaphelenchus xylophilus, and the like, but the present invention is not limited thereto.


The pest control agent including the compound according to the present invention as an active ingredient has a significant control effect against the above-described harmful crops which damage lowland crops, upland crops, fruit trees, vegetables, and other crops and ornamental flowers, and therefore, the effect as a pest control agent of the present invention can be obtained by treating the paddy field water, plant stems and leaves, or soil of the crops of lowland, upland, fruit trees, vegetables, other crops, ornamental flowers, and the like during the seasons in which the appearance of such pests is expected, or before or at the point when the pest appearance is observed.


The pest control agent including the compound according to the present invention as an active ingredient has a significant control effect against stored grain pests and the like generated during storage of the harvest. That is, the the pest control agent having the compound of the present invention as an active ingredient may be subjected to a treatment after the harvest (post harvest) such as spray-spreading, coating, dipping, dressing, fumigation/smoking, pressurized injection, and the like with respect to the harvest or the place for storage of the harvest.


Further, the pest control agent including the compound according to the present invention as an active ingredient can be applied to plant seeds to prevent the damage caused by pests generated in the plants after seeding. That is, the pest control agent having the compound of the present invention as an active ingredient may be subjected to a treatment such as spray-spreading, dipping, dressing, and the like on the plant seeds in an effective amount for controlling the pests as it is, as an adequate dilution with water or the like, or as a suspension to bring the compound of the present invention into contact with the plant seeds.


The plant seeds refer to those used for breeding in agriculture by storing the nutrients for seedling germination, and examples thereof include seeds such as corn, soybeans, red beans, cotton, rice, sugar beet, wheat, barley, sunflower, tomato, cucumber, eggplant, spinach, sting beans, squash, sugarcane, tobacco, pimento, canola, and the like, seed tubers such as taro, potato, sweet potato, konjac, and the like, bulbs such as edible lily, tulips, and the like, and seed balls such as rakkyo and the like.


The pest control agent having the compound of the present invention as an active ingredient has a significant control effect against insanitary pests such as Diptera pests (Culex pipiens pallens, Culex pipiens, Chironomidae, houseflies, sandflies, horsefly, and the like) Dictyoptera pests (Blattella germanica, Periplaneta fuliginosa, Periplaneta americana, and the like), and other pests.


The pest control agent having the compound of the present invention as an active ingredient has a significant control effect against wood-feeding pests such as termites, Lyctusbrunneus, Rhizopertha dominica, Anobiidae, Cerambycidae, and the like, thus, the above-described wood-feeding pests can be controlled by treatment of wood, soil, buildings, and the like with the pest control agent.


Since the compound of the present invention exhibits a control effect against various pests and also exhibits an effect of protecting useful crops and an excellent control effect as a pesticide or a miticide at a low dose, it has an effect of contributing to reduction in an environmental impact. In addition, the compound of the present invention also exerts an excellent control effect when used in combination with other agricultural/horticultural pesticides, miticides, nematocides, fungicides, herbicides, plant growth regulators, biological agricultural chemicals, or the like.


For the use of the compound of the present invention, the compound can be put to practical use as a preparation in any form such as a soluble concentrate, an emulsifiable concentrate, a wettable powder, a water-soluble powder, a water dispersible granule, a water-soluble granule, a suspension concentrate, a concentrated emulsion, a suspoemulsion, a microemulsion, a dustable powder, a granule, a tablet, and an emulsifiable gel, typically by mixing the compound with a suitable solid carrier or liquid carrier, further if desired by adding to the resultant mixture, a surfactant, a penetrant, a spreader, a thickener, an antifreezing agent, a binder, an anticaking agent, a disintegrant, a defoaming agent, an antiseptic or a stabilizer. In addition, from the labor-saving and safety-enhancing viewpoints, the compound can be put to use by encapsulating the above preparation in any form in a water-soluble packaging material such as a water-soluble capsule and a bag of water-soluble film.


The inert carrier which can be used in the present invention may be solids or liquids, and examples thereof include soybean powders, grain powders, wood powders, bark powders, sawdust powders, tobacco stem powders, walnut shell powders, brans, cellulose powders, residues from plant extraction, synthetic polymers such as pulverized synthetic resins, clays (for example, kaolin, bentonite, acidic white clay), talcs (for examples, talc, pyrophyllite, etc.), silica (for examples, diatomaceous earth, sand, mica, white carbon [hydrous silica powders, synthetic high dispersity silicates called hydrous silicate, there are also products containing calcium silicate as a main component]), activated carbon, sulfur powder, pumice, calcined diatomaceous powders, pulverized bricks, fly ash, sand, inorganic mineral powders such as calcium carbonate, calcium phosphate, and the like, chemical fertilizers such as ammonium sulfate, ammonium phosphate, ammonium nitrate, urea, ammonium chloride, and the like, a compost, and others, which are used alone or as a mixture of two or more kinds thereof.


Materials which can be used as the liquid inert carrier are selected from those having the function as solvent, as well as those capable of dispersing the active ingredient compound with the aid of an adjuvant even if the inert carrier does not have a function as a solvent. Representative examples thereof include the carriers listed below: water, alcohols (for example, methanol, ethanol, isopropanol, butanol, ethylene glycol, and the like), ketones (for example, acetone, methyl ethyl ketone, methyl isobutyl ketone, diisobutylketone, cyclohexanone, and the like), ethers (for example, diethyl ether, dioxane, cellosolve, diisopropyl ether, tetrahydrofuran, and the like), aliphatic hydrocarbons (for example, kerosene, mineral oil, and the like), aromatic hydrocarbons (for example, benzene, toluene, xylene, solvent naphtha, alkyl naphthalene, and the like), halogenated hydrocarbons (for example, dichloromethane, chloroform, tetrachlorocarbon, chlorobenzene, and the like), esters (for example, ethyl acetate, butyl acetate, ethyl propionate, diisobutyl phthalate, dibutyl phthalate, dioctyl phthalate, and the like), amides (for example, dimethyl formamide, diethyl formamide, dimethyl acetamide, and the like), and nitriles (for example, acetonitrile, and the like), which are used alone or as mixtures of two or more kinds thereof.


These solid and liquid carriers may be used alone or in a combination of two or more kinds thereof.


Examples of the surfactant include nonionic surfactants such as polyoxyethylene alkyl ethers, polyoxyethylene alkyl (mono- or di-)phenyl ethers, polyoxyethylene (mono-, di-, or tri-)styryl phenyl ethers, polyoxyethylene-polyoxypropylene block copolymers, polyoxyethylene aliphatic acid (mono- or di-) esters, sorbitan aliphatic acid esters, polyoxyethylene sorbitan aliphatic acid esters, castor oil ethylene-oxide adducts, acetylene glycol, acetylene alcohols, acetylene glycol ethylene-oxide adducts, acetylene alcohol ethylene-oxide adducts, alkylglucosides, and the like; anionic surfactants such as alkyl sulfate ester salts, alkylbenzene sulfonates, lignin sulfonates, alkyl sulfosuccinates, naphthalene sulfonates, alkylnaphthalene sulfonates, salts of naphthalene sulfonate formalin condensate, salts of alkylnaphthalene sulfonate formalin condensate, polyoxyethylenealkylether sulfate or phosphate esters salts, polyoxyethylene (mono- or di-) alkylphenyl ether sulfate or phosphate esters, polyoxyethylene (mono-, di-, or tri-) styrylphenyl ether sulfate or phosphate esters, polycarboxylic acid salts (such as polyacrylic acid salts, polymaleic acid salts, maleic acid-olefin copolymers, and the like), polystyrene sulfonates, and the like; cationic surfactants such as alkylamine salts, alkyl quaternary ammonium salts, and the like; amphoteric surfactants such as amino acid-type surfactants, betaine-type surfactants, and the like; silicone-based surfactants; and fluorinated surfactants.


The content of these surfactants is not particularly limited, but it is preferably in the range of usually 0.05 part by weight to 20 parts by weight, with respect to 100 parts by weight of the preparation of the present invention. In addition, these surfactants may be used alone or in combination of two or more kinds thereof.


In order to control various pests, an amount effective for blight control can be applied as it is or as an adequate dilution with water or the like, or as a suspension, to the crops on which appearance of the corresponding pests is expected or to places where such occurrence is not preferable. The amount of use depends on various factors such as, for example, the purpose, the pest to be controlled, the state of plant growth, trends in pest appearance, climate, environmental conditions, Formulation, method of use, place of use, timing of use, and the like, but it is preferable to use the active ingredient in the concentration of 0.0001 ppm to 5000 ppm, and preferably 0.01 ppm to 1000 ppm. The dose that can be used per 10 a is generally in the range of 1 g to 300 g of the active ingredient.


The amount of the active ingredient of the compound of the present invention is usually 0.1% by weight to 20% by weight for powders, 5% by weight to 50% by weight for emulsifiable concentrates, 3% by weight to 90% by weight for wettable powders, 0.1% by weight to 20% by weight for granules, 5% by weight to 90% by weight for flowable Formulations, or 3% by weight to 90% by weight for water dispersible granules. The amount of the carrier in each form is usually 60% by weight to 99.9% by weight for powders, 40% by weight to 95% by weight for emulsifiable concentrates, 10% by weight to 90% by weight for wettable powders, 80% by weight to 99.9% by weight for granules, 10% by weight to 95% by weight for flowable Formulations, or 10% by weight to 90% by weight for water dispersible granules. Further, the amount of the adjuvant is usually 0.1% by weight to 20% by weight for powders, 1% by weight to 20% by weight for emulsifiable concentrates, 0.1% by weight to 20% by weight for wettable powders, 0.1% by weight to 20% by weight for granules, 0.1% by weight to 20% by weight for flowable Formulations, and 0.1% by weight to 20% by weight for water dispersible granules.


When the compound of the present invention is used as an agricultural chemical, it may be used, if required, as a mixture with other herbicides, various pesticides, miticides, nematocides, fungicides, plant growth regulators, synergists, fertilizers, soil conditioners, or the like to be applied during the preparation or the dusting.


All literature, patent applications, and technical specifications cited in the present specification are herein incorporated by reference as if each such individual piece of literature, patent application, and technical specification were specifically and individually indicated to be incorporated herein by reference.


EXAMPLES

Representative Examples of the present invention will be described with reference to the following Examples, but the present invention is not limited thereto. In the present Examples, DMF means N,N-dimethyl formamide, THF means tetrahydrofuran, IPE means isopropyl ether, DMI means 1,3-dimethyl-2-imidazolidinone, and DMSO means dimethylsulfoxide.


Furthermore, “%” is based on mass unless specified otherwise.


Example 1
Preparation of N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-2-fluoro-3-(N-methylbenzamide)benzamide (Compound No. 7-1574)



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<1-1>


Preparation of 4-(perfluoropropan-2-yl)-2-(trifluoromethyl)aniline



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100 g (0.608 mol) of 2-(trifluoromethyl)aniline, 131 g (0.639 mol) of 85% sodium hydrosulfite, and 20.9 g (0.0608 mol) of tetrabutylammonium hydrogen sulfate were charged to a mixed solution of 1500 ml of ethyl acetate and 1500 ml of water, and 53.9 g (0.639 mol) of sodium hydrogen carbonate was added thereto. 198 g (0.669 mol) of heptafluoroisopropyl iodide was added dropwise thereto at room temperature, followed by stirring at room temperature for 6 hours. After the liquid separation, the solvent of the organic layer was evaporated under reduced pressure, and 500 ml of ethyl acetate was charged thereto. 160 g (0.608 mol) of a 4 M hydrogen chloride/ethyl acetate solution was added dropwise thereto, followed by stirring at room temperature for 30 minutes, and then stirring at 5° C. for 1 hour. After the filtration, the filtrate was washed with water and a saturated aqueous sodium hydrogen carbonate in this order, and then dried over anhydrous magnesium sulfate, and the solvent was evaporated under reduced pressure. The obtained residue was purified by silica gel column chromatography (eluent solvent; hexane:ethyl acetate=10:1) to prepare 60.0 g (yield 30%) of a target compound.



1H-NMR (CDCl3, ppm) δ 4.49 (2H, broad-s), 6.81 (1H, d, J=8.3 Hz), 7.48 (1H, d, J=8.3 Hz), 7.64 (1H, s).


<1-2>


Preparation of 2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)aniline



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100 g (0.273 mol) of 4-(perfluoropropan-2-yl)-2-(trifluoromethyl)aniline was charged to 500 ml of DMF, and 52.1 g (0.287 mol) of N-bromosuccinimide was charged in separate portions thereto over 30 minutes. After stirring at 60° C. for 2 hours, and then cooling to room temperature, the mixture was discharged to 2000 ml of water. The mixture was extracted with ethyl acetate, then washed with saturated brine, and dried over anhydrous magnesium sulfate. The solvent was evaporated under reduced pressure and the obtained residue was purified by silica gel column chromatography (eluent solvent; hexane:ethyl acetate=20:1) to prepare 89.0 g (yield 80%) of a target compound.



1H-NMR (CDCl3, ppm) δ 5.03 (2H, broad-s), 7.61 (1H, s), 7.79 (1H, s).


<1-3>


Preparation of N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-2-chloro-3-nitrobenzamide



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3.60 g (8.82 mmol) of 2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)aniline was charged to 20 ml of anhydrous THF, and cooled to −70° C. under a nitrogen atmosphere. 4.85 ml (9.70 mmol) of a 2.0 M lithium diisopropyl amide hexane solution was added dropwise thereto, then 2.34 g (10.7 mmol) of acid chloride which was prepared from 2-chloro-3-nitrobenzoic acid and thionyl chloride was dissolved in 5 ml of anhydrous THF, and was added dropwise thereto, followed by stirring at −70° C. for 30 minutes and then stirring at room temperature for 30 minutes. The mixture was discharged to an aqueous ammonium chloride solution, then extracted with ethyl acetate, and dried over anhydrous magnesium sulfate. The solvent was evaporated under reduced pressure and the obtained residue was purified by silica gel column chromatography (eluent solvent; hexane:ethyl acetate=10:1→8:2→3:1) to prepare 1.76 g (yield: 34%) of a target compound.



1H-NMR (CDCl3, ppm) δ 7.61 (1H, t, J=7.8 Hz), 7.67 (1H, broad-s), 7.93-7.97 (3H, m), 8.18 (1H, broad-s).


<1-4>


Preparation of N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-2-fluoro-3-nitrobenzamide



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To a solution of N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-2-chloro-3-nitrobenzamide 4.89 g (8.27 mmol) in 50 ml of anhydrous DMF was added 2.40 g (41.3 mmol) of potassium fluoride (spray-dried product) under a flow of nitrogen, followed by stirring at 130° C. for 10 hours. Liquid separation was carried out by adding ethyl acetate, hexane, and water to the reaction mixture, and then the organic layer was washed with water and saturated brine, and dried over anhydrous magnesium sulfate. The solvent was evaporated under reduced pressure and the obtained residue was purified by silica gel column chromatography (eluent solvent; hexane:ethyl acetate=10:1) to prepare 0.940 g (yield 20%) of a target compound.



1H-NMR (CDCl3, ppm) δ 7.53 (1H, t, J=7.3 Hz), 7.93 (1H, broad-s), 8.17-8.18 (2H, m), 8.28-8.32 (1H, m), 8.44-8.48 (1H, m).


<1-5>


Preparation of 3-amino-N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-2-fluorobenzamide



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0.940 g (1.63 mmol) of N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-2-fluoro-3-nitrobenzamide and 0.960 g (5.05 mmol) of stannous chloride (anhydrous) were added to 10 ml of ethanol, and 1.02 ml (9.78 mmol) of concentrated hydrochloric acid was added thereto, followed by stirring at 60° C. for 4 hours. The reaction mixture was adjusted to pH 10 by the addition of an aqueous sodium hydroxide solution, and the precipitated insolubles were removed by filtration using Celite. The filtrate on Celite was washed with ethyl acetate. The filtrate was extracted with ethyl acetate, and the organic layer was washed with a 20% aqueous sodium hydroxide solution and saturated brine, and then dried over anhydrous magnesium sulfate. The solvent was evaporated under reduced pressure and the obtained residue was purified by silica gel column chromatography (eluent solvent; hexane:ethyl acetate=4:1) to prepare 0.930 g (yield 99%) of a target compound.



1H-NMR (CDCl3, ppm) δ 3.93 (2H, broad-s), 6.99-7.04 (1H, m), 7.11 (1H, t, J=7.8 Hz), 7.47-7.49 (1H, m), 7.91 (1H, s), 8.14 (1H, s), 8.28 (1H, d, J=14.6 Hz).


<1-6>


Preparation of N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-2-fluoro-3-(methylamino)benzamide



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0.930 g (1.71 mmol) of 3-amino-N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-2-fluorobenzamide was added to 5 ml of concentrated sulfuric acid, and 10 ml of a 37% aqueous formaldehyde solution was charged dropwise thereto at 40° C. The reaction mixture was poured into ice-water, adjusted to pH 10 using an aqueous sodium hydroxide solution, and extracted with the addition of ethyl acetate. The organic layer was washed with a 20% aqueous sodium hydroxide solution and saturated brine, and then dried over anhydrous magnesium sulfate. The solvent was evaporated under reduced pressure and the obtained residue was purified by silica gel column chromatography (eluent solvent; hexane:ethyl acetate=8:1) to prepare 0.690 g (yield 72%) of a target compound.



1H-NMR (CDCl3, ppm) δ 2.94 (3H, s), 4.14 (1H, broad-s), 6.88-6.93 (1H, m), 7.18 (1H, t, J=7.8 Hz), 7.37-7.41 (1H, m), 7.90 (1H, s), 8.13 (1H, s), 8.27 (1H, d, J=14.6 Hz).


[1-7] Preparation of N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-2-fluoro-3-(N-methylbenzamide)benzamide (Compound No. 7-1574)



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To a solution of 1.54 g (2.75 mmol) of N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-2-fluoro-3-(methylamino)benzamide and 0.330 g (4.13 mmol) of pyridine in 5 ml of THF was added 0.460 g (3.30 mmol) of benzoyl chloride, followed by stirring at 60° C. for 5 hours. To the reaction mixture were added water and ethyl acetate, and the organic layer was washed with 1 M hydrochloric acid, a saturated aqueous sodium hydrogen carbonate solution, and saturated brine, and then dried over anhydrous magnesium sulfate. The solvent was evaporated under reduced pressure and the obtained residue was purified by silica gel column chromatography (eluent solvent; hexane:ethyl acetate=8:1), and the obtained solid was washed with IPE to prepare 1.45 g (yield 80%) of a target compound.



1H-NMR (CDCl3, ppm) δ 3.50 (3H, s), 6.99-7.33 (6H, m), 7.43-7.45 (1H, m), 7.90 (1H, s), 7.97-8.06 (2H, m), 8.13 (1H, s).


Example 2
Preparation of 2-chloro-N-(3-(2,6-dibromo-4-(perfluoropropan-2-yl)phenylcarbamoyl)-2-fluorophenyl)nicotinamide (Compound No. 6-1140)



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<2-1>


Preparation of 4-(perfluoropropan-2-yl)aniline



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100 g (1.02 mol) of aniline, 230 g (1.12 mol) of 85% sodium hydrosulfite, and 35.1 g (0.100 mol) of tetrabutylammonium hydrogen sulfate were charged to a mixed solution of 1500 ml of t-butyl methyl ether and 1500 ml of water, and 94.7 g (1.12 mol) of sodium hydrogen carbonate was added thereto. 350 g (1.12 mol) of heptafluoroisopropyl iodide was added dropwise thereto at room temperature, followed by stirring at room temperature for 6 hours. After the liquid separation, the organic layer was washed with 1 M hydrochloric acid, water, and a saturated aqueous sodium hydrogen carbonate solution, and then dried over anhydrous sodium sulfate. The solvent was evaporated under reduced pressure, and 500 ml of ethyl acetate was charged thereto. 255 g (1.02 mol) of a 4 M hydrogen chloride/ethyl acetate solution was added dropwise thereto, followed by stirring at room temperature for 30 minutes and at 5° C. for 1 hour. The precipitated solid was separated by filtration, and the solid was charged to 1000 ml of ethyl acetate, adjusted to pH 8 to 9 by the addition of 1000 ml of a saturated aqueous sodium hydrogen carbonate solution at 20° C. or lower, and subjected to liquid separation. The organic layer was dried over anhydrous sodium sulfate, and then the solvent was evaporated under reduced pressure to prepare 188 g (yield 71%) of a target compound.



1H-NMR (CDCl3, ppm) δ 3.92 (2H, broad-s), 6.69-6.74 (2H, m), 7.35 (2H, d, J=9.3 Hz).


<2-2>


Preparation of 2,6-dibromo-4-(perfluoropropan-2-yl)aniline



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216 g (0.802 mol) of 4-(perfluoropropan-2-yl)aniline was charged to 863 ml of DMF, followed by cooling to 5° C. 285 g (1.60 mol) of N-bromosuccinimide was charged in separate portions thereto over 1 hour. The mixture was stirred at room temperature for 1 hour and then stirred at 37° C. for 2 hours. The mixture was discharged to 2000 ml of water, extracted with 2000 ml of ethyl acetate, and washed with 1000 ml of saturated brine. After dried over anhydrous magnesium sulfate, the solvent was evaporated under reduced pressure. The obtained residue was purified by silica gel column chromatography (eluent solvent; hexane:ethyl acetate=20:1) to prepare 304 g (yield 90%) of a target compound.



1H-NMR (CDCl3, ppm) δ 4.88 (2H, broad-s), 7.59 (2H, s).


<2-3>


Preparation of 2-chloro-N-(2,6-dibromo-4-(perfluoropropan-2-yl)phenyl)-3-nitrobenzamide



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According to the method of 1-3 of Example 1, a target compound was prepared from 2,6-dibromo-4-(perfluoropropan-2-yl)aniline.



1H-NMR (CDCl3, ppm) δ 7.58 (1H, t, J=7.8 Hz), 7.66 (1H, broad-s), 7.90 (2H, s), 7.93 (1H, dd, J=1.5, 7.8 Hz), 7.98 (1H, d, J=7.8 Hz).


<2-4>


Preparation of N-(2,6-dibromo-4-(perfluoropropan-2-yl)phenyl)-2-fluoro-3-nitrobenzamide



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According to the method of 1-4 of Example 1, a target compound was prepared from 2-chloro-N-(2,6-dibromo-4-(perfluoropropan-2-yl)phenyl)-3-nitrobenzamide.



1H-NMR (CDCl3, ppm) δ 7.51-7.55 (1H, m), 7.90 (2H, s), 8.16 (1H, d, J=11.7 Hz), 8.27-8.31 (1H, m), 8.48 (1H, t, J=6.3 Hz).


<2-5>


Preparation of 3-amino-N-(2,6-dibromo-4-(perfluoropropan-2-yl)phenyl)-2-fluorobenzamide



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According to the method of 1-5 of Example 1, a target compound was prepared from N-(2,6-dibromo-4-(perfluoropropan-2-yl)phenyl)-2-fluoro-3-nitrobenzamide.



1H-NMR (CDCl3, ppm) δ 3.93 (2H, broad-s), 6.99-7.04 (1H, m), 7.11 (1H, t, J=7.8 Hz), 7.47-7.49 (1H, m), 7.91 (1H, s), 8.14 (1H, s), 8.28 (1H, d, J=14.6 Hz).


<2-6>


Preparation of 2-chloro-N-(3-(2,6-dibromo-4-(perfluoropropan-2-yl)phenylcarbamoyl)-2-fluorophenyl)nicotinamide (Compound No. 6-1140)



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According to the method of 1-7 of Example 1, a target compound was prepared from 3-amino-N-(2,6-dibromo-4-(perfluoropropan-2-yl)phenyl)-2-fluorobenzamide and 2-chloronicotinic acid chloride.



1H-NMR (CDCl3, ppm) δ 7.40-7.49 (2H, m), 7.89 (2H, s), 7.94-7.96 (1H, m), 8.13 (1H, d, J=12.7 Hz), 8.32-8.34 (1H, m), 8.57-8.59 (1H, m), 8.67-8.71 (1H, m), 8.75 (1H, broad-s).


Example 3
Preparation of 3-benzamide-2-fluoro-N-(4-(perfluoropropan-2-yl)-2,6-bis(trifluoromethyl)phenyl)benzamide (Compound No. 6-2110)



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<3-1>


Preparation of 2,6-diiodo-4-(perfluoropropan-2-yl)aniline



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To a solution of 5.74 g (22.0 mmol) of 4-(perfluoropropan-2-yl)aniline obtained in 2-1 of Example 2 in 50 ml of ethanol was added 2.16 g (22.0 mmol) of concentrated sulfuric acid at 5° C. The reaction mixture was warmed to room temperature, and 10.0 g (44.0 mmol) of N-iodosuccinimide was added thereto, followed by stirring for 3 hours. The reaction mixture was neutralized with a saturated aqueous sodium hydrogen carbonate solution. The precipitated crystals were filtered, washed with water, and then dried to prepare 9.00 g (yield 80%) of a target compound.



1H-NMR (CDCl3, ppm) δ 4.95 (2H, broad-s), 7.79 (2H, s).


<3-2>


Preparation of 2-chloro-N-(2,6-diiodo-4-(perfluoropropan-2-yl)phenyl)-3-nitrobenzamide



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To a solution of 40.0 g (78.0 mmol) of 2,6-diiodo-4-(perfluoropropan-2-yl)aniline in 100 ml of DMI was added 20.6 g (94.0 mmol) of 2-chloro-3-nitrobenzoyl chloride, followed by stirring at 135° C. for 3 hours. After cooling to room temperature, the reaction mixture was poured into 1000 ml of water. After extraction with the addition of 1000 ml of ethyl acetate, the organic layer was washed with water and then dried over anhydrous magnesium sulfate. The solvent was evaporated under reduced pressure and the obtained residue was washed with hexane to prepare 56.2 g (yield 99%) of a target compound.



1H-NMR (CDCl3, ppm) δ 7.58 (1H, t, J=8.3 Hz), 7.70 (1H, d, J=3.4 Hz), 7.93 (1H, dd, J=1.5, 6.3 Hz), 8.08-8.10 (1H, m), 8.13 (2H, s).


<3-3>


Preparation of N-(2,6-diiodo-4-(perfluoropropan-2-yl)phenyl)-2-fluoro-3-nitrobenzamide



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According to the method of 1-4 of Example 1, a target compound was prepared from 2-chloro-N-(2,6-diiodo-4-(perfluoropropan-2-yl)phenyl)-3-nitrobenzamide.


1H-NMR (CDCl3, ppm) δ 7.52-7.55 (1H, m), 8.12-8.18 (3H, m), 8.29-8.32 (1H, m), 8.48-8.51 (1H, m).


<3-4>


Preparation of 3-amino-N-(2,6-diiodo-4-(perfluoropropan-2-yl)phenyl)-2-fluorobenzamide



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According to the method of 1-5 of Example 1, a target compound was prepared from N-(2,6-diiodo-4-(perfluoropropan-2-yl)phenyl)-2-fluoro-3-nitrobenzamide.



1H-NMR (CDCl3, ppm) δ 3.93 (2H, broad-s), 6.99-7.04 (1H, m), 7.08 (1H, t, J=7.8 Hz), 7.39-7.43 (1H, m), 8.10 (2H, s), 8.72 (1H, d, J=11.2 Hz).


<3-5>


Preparation of 3-benzamide-N-(2,6-diiodo-4-(perfluoropropan-2-yl)phenyl)-2-fluorobenzamide (Compound No. 6-1260)



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According to the method of 1-7 of Example 1, a target compound was prepared from 3-amino-N-(2,6-diiodo-4-(perfluoropropan-2-yl)phenyl)-2-fluorobenzamide.



1H-NMR (CDCl3, ppm) δ 7.39 (1H, t, J=7.8 Hz), 7.52-7.57 (4H, m), 7.60-7.63 (2H, m), 7.93-7.94 (4H, m), 8.70 (1H, t, J=6.3 Hz).


<3-6>


Preparation of 3-benzamide-2-fluoro-N-(4-(perfluoropropan-2-yl)-2,6-bis(trifluoromethyl)phenyl)benzamide (Compound No. 6-2110)



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A solution of 1.95 g (2.59 mmol) of 3-benzamide-N-(2,6-diiodo-4-(perfluoropropan-2-yl)phenyl)-2-fluorobenzamide, 0.10 g (0.520 mmol) of copper iodide, and 1.24 g (6.48 mmol) of methyl fluorosulfonyl difluoroacetate in 50 ml of DMF was stirred at 100° C. for 6 hours. The reaction mixture was cooled to room temperature, and then 10 ml of water and 100 ml of ethyl acetate were added thereto, followed by filtration through Celite. The organic layer of the liquid was washed with water and a saturated aqueous sodium hydrogen carbonate solution, and then dried over anhydrous magnesium sulfate. The solvent was evaporated under reduced pressure and the obtained residue was purified by silica gel column chromatography (eluent solvent; hexane:ethyl acetate=1:1). The obtained solid was washed with hexane to prepare 0.840 g (yield 51%) of a target compound.



1H-NMR (CDCl3, ppm) δ 7.36-7.40 (1H, m), 7.53-7.64 (3H, m), 7.84-7.97 (1H, m), 7.92-7.94 (2H, m), 8.04-8.07 (1H, m), 8.08-8.13 (1H, m), 8.20 (2H, s), 8.68-8.72 (1H, m).


Example 4
Preparation of N-(2,6-dibromo-4-(perfluorobutan-2-yl)phenyl)-2-fluoro-3-(N-methylbenzamide)benzamide (Compound No. 7-1182)



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<4-1>


Preparation of 4-(perfluorobutan-2-yl)aniline



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4.90 g (52.6 mmol) of aniline, 10.1 g (58.0 mmol) of 85% sodium hydrosulfite, and 1.90 g (5.77 mmol) of tetrabutylammonium hydrogen sulfate were charged to a mixed solution of 150 ml of t-butyl methyl ether and 150 ml of water using a light-shielded reaction vessel, and 4.84 g (57.6 mmol) of sodium hydrogen carbonate was added thereto. 20.0 g (57.8 mmol) of nonafluoro-s-butyliodide was added dropwise thereto at room temperature, followed by stirring at room temperature for 5 hours. The organic phase was collected by separation, washed with 2 mol/L of an aqueous hydrochloric acid solution twice, and then washed with saturated brine, an aqueous sodium hydrogen carbonate solution, and saturated brine. The organic layer was dried over anhydrous magnesium sulfate, and then the solvent was evaporated under reduced pressure to prepare 8.32 g (yield 51%) of a target compound.



1H-NMR (CDCl3, ppm) δ 3.92 (2H, broad-s), 6.72 (2H, d, J=8.8 Hz), 7.34 (2H, d, J=8.8 Hz).


<4-2>


Preparation of 2,6-dibromo-4-(perfluorobutan-2-yl)aniline



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According to the method of 2-2 of Example 2, a target compound was prepared from 4-(perfluorobutan-2-yl)aniline.



1H-NMR (CDCl3, ppm) δ 4.89 (2H, broad-s), 7.57 (2H, s).


<4-3>


Preparation of 2-chloro-N-(2,6-dibromo-4-(perfluorobutan-2-yl)phenyl)-3-nitrobenzamide



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To 27 ml of DMI were added 9.90 g (21.1 mmol) of 2,6-dibromo-4-(perfluorobutan-2-yl)aniline and 4.60 g (20.9 mmol) of 2-chloro-3-nitrobenzoyl chloride, followed by stirring at 140° C. for 4 hours. To the reaction solution were added water and ethyl acetate, and the organic phase was extracted, and washed with 1 mol/L of an aqueous sodium hydroxide solution, saturated brine, and dried over anhydrous magnesium sulfate. Then, the solvent was evaporated under reduced pressure. The obtained residue was purified by silica gel column chromatography (eluent solvent; hexane:ethyl acetate=20:1--10:1-+5:1-+3:1) to prepare 5.44 g (yield 40%) of a target compound.



1H-NMR (CDCl3, ppm) δ 7.52-7.61 (2H, m), 7.89 (2H, s), 7.94 (1H, dd, J=1.5, 8.3 Hz), 7.99 (1H, d, J=7.8 Hz).


<4-4>


Preparation of N-(2,6-dibromo-4-(perfluorobutan-2-yl)phenyl)-2-fluoro-3-nitrobenzamide



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To 108 ml of DMSO were added 5.44 g (8.34 mmol) of 2-chloro-N-(2,6-dibromo-4-(perfluorobutan-2-yl)phenyl)-3-nitrobenzamide and 4.90 g (84.3 mmol) of potassium fluoride (spray-dried product), followed by stirring at 145° C. for 2 hours. The reaction solution was poured into ice-water to precipitate the crystal, and the obtained crystals were filtered and washed with hexane. The obtained crystals were purified by silica gel column chromatography (eluent solvent; hexane:ethyl acetate=5:1) to prepare 2.42 g (yield 46%) of a target compound.



1H-NMR (CDCl3, ppm) δ 7.53-7.54 (1H, m), 7.89 (2H, s), 8.17 (1H, d, J=12.2 Hz), 8.29-8.30 (1H, m), 8.48-8.49 (1H, m).


<4-5>


Preparation of 3-amino-N-(2,6-dibromo-4-(perfluorobutan-2-yl)phenyl)-2-fluorobenzamide



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According to the method of 1-5 of Example 1, a target compound was prepared from N-(2,6-dibromo-4-(perfluorobutan-2-yl)phenyl)-2-fluoro-3-nitrobenzamide.



1H-NMR (CDCl3, ppm) δ 3.92 (2H, broad-s), 6.99-7.04 (1H, m), 7.11-7.12 (1H, m), 7.48-7.52 (1H, m), 7.86 (2H, s), 8.22 (1H, d, J=14.1 Hz).


<4-6>


Preparation of N-(2,6-dibromo-4-(perfluorobutan-2-yl)phenyl)-2-fluoro-3-(methylamino)benzamide



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According to the method of 1-6 of Example 1, a target compound was prepared from 3-amino-N-(2,6-dibromo-4-(perfluorobutan-2-yl)phenyl)-2-fluorobenzamide.



1H-NMR (CDCl3, ppm) δ 2.95 (3H, s), 4.14 (1H, broad-s), 6.91-6.92 (1H, m), 7.17-7.21 (1H, m), 7.39-7.43 (1H, m), 7.85 (2H, s), 8.21 (1H, d, J=14.1 Hz).


<4-7>


Preparation of N-(2,6-dibromo-4-(perfluorobutan-2-yl)phenyl)-2-fluoro-3-(N-methylbenzamide)benzamide (Compound No. 7-1182)



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According to the method of 1-7 of Example 1, a target compound was prepared from N-(2,6-dibromo-4-(perfluorobutan-2-yl)phenyl)-2-fluoro-3-(methylamino)benzamide.



1H-NMR (CDCl3, ppm) δ 3.51 (3H, s), 7.22-7.44 (7H, m), 7.85 (2H, s), 8.00-8.03 (2H, m).


Example 5
Preparation of N-(2-bromo-6-(perfluoroethyl)-4-(perfluoropropan-2-yl)phenyl)-3-(4-cyanobenzamide)-2-fluorobenzamide (Compound No. 6-5911)



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5-1>


Preparation of 2-(perfluoroethyl)-4-(perfluoropropan-2-yl)aniline



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According to the method of 1-1 of Example 1, a target compound was prepared from 4-(perfluoropropan-2-yl)aniline obtained in Example 2-1 and 1,1,2,2,2-pentafluoroethyliodide.



1H-NMR (CDCl3, ppm) δ 4.56 (2H, broad-s), 6.79 (1H, d, J=8.8 Hz), 7.47 (1H, d, J=8.8 Hz), 7.53 (1H, s).


<5-2>


Preparation of 2-bromo-6-(perfluoroethyl)-4-(perfluoropropan-2-yl)aniline



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According to the method of 1-2 of Example 1, a target compound was prepared from 2-(perfluoroethyl)-4-(perfluoropropan-2-yl)aniline.



1H-NMR (CDCl3, ppm) δ 5.14 (2H, broad-s), 7.58 (1H, s), 7.81 (1H, s).


<5-3>


Preparation of N-(2-bromo-6-(perfluoroethyl)-4-(perfluoropropan-2-yl)phenyl)-2-chloro-3-nitrobenzamide



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According to the method of 4-3 of Example 4, a target compound was prepared from 2-bromo-6-(perfluoroethyl)-4-(perfluoropropan-2-yl)aniline.



1H-NMR (CDCl3, ppm) δ 7.56-7.61 (1H, m), 7.73 (1H, s), 7.88 (1H, d, J=1.5 Hz), 7.92-7.98 (2H, m), 8.21 (1H, s).


<5-4>


Preparation of N-(2-bromo-6-(perfluoroethyl)-4-(perfluoropropan-2-yl)phenyl)-2-fluoro-3-nitrobenzamide



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According to the method of 1-4 of Example 1, a target compound was prepared from N-(2-bromo-6-(perfluoroethyl)-4-(perfluoropropan-2-yl)phenyl)-2-chloro-3-nitrobenzamide.


APCI-MS m/z (M+1):626


<5-5>


Preparation of 3-amino-N-(2-bromo-6-(perfluoroethyl)-4-(perfluoropropan-2-yl)phenyl)-2-fluorobenzamide



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According to the method of 1-5 of Example 1, a target compound was prepared from N-(2-bromo-6-(perfluoroethyl)-4-(perfluoropropan-2-yl)phenyl)-2-fluoro-3-nitrobenzamide.



1H-NMR (CDCl3, ppm) δ 3.92 (2H, broad-s), 6.99-7.04 (1H, m), 7.05-7.18 (1H, m), 7.46-7.51 (1H, m), 7.85 (1H, broad-s), 8.17 (1H, broad-s), 8.34 (1H, d, J=15.1 Hz).


<5-6>


Preparation of N-(2-bromo-6-(perfluoroethyl)-4-(perfluoropropan-2-yl)phenyl)-3-(4-cyanobenzamide)-2-fluorobenzamide (Compound No. 6-5911)



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According to the method of 1-7 of Example 1, a target compound was prepared from 3-amino-N-(2-bromo-6-(perfluoroethyl)-4-(perfluoropropan-2-yl)phenyl)-2-fluorobenzamide and 4-cyanobenzoylchloride.



1H-NMR (CDCl3, ppm) δ 7.41 (1H, t, J=8.3 Hz), 7.84-7.87 (3H, m), 7.91-7.95 (1H, m), 8.03-8.05 (2H, m), 8.10 (1H, broad-s), 8.17-8.20 (2H, m), 8.63-8.67 (1H, m).


Example 6
Preparation of N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-6-(N-methylbenzamide)picolinamide (Compound No. 17-1103)



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<6-1>


Preparation of N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-6-chloropicoline amide



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According to the method of 1-3 of Example 1, a target compound was prepared from 2-chloropyridine-6-carboxylic acid chloride prepared from 2-chloropyridine-6-carboxylic acid and thionyl chloride, and 2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)aniline obtained in 1-2 of Example 1.



1H-NMR (CDCl3, ppm) δ 7.59 (1H, d, J=7.3 Hz), 7.90-7.93 (2H, m), 8.14 (1H, s), 8.20-8.24 (1H, m), 9.60 (1H, s).


<6-2>


Preparation of N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-6-(methylamino)picolinamide



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To a solution of 0.100 g (0.180 mmol) of N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-6-chloropicoline amide in 5 ml of 1,4-dioxane were added 0.00600 g (0.0360 mmol) of copper sulfate and 0.140 g (1.80 mmol) of a 40% aqueous methylamine solution, followed by stirring at an oil bath temperature 80° C. for 3 hours under an enclosed condition. The reaction liquid was returned to room temperature and opened, and water and ethyl acetate were added thereto. The organic layer was washed with water and saturated brine, and dried over anhydrous magnesium sulfate. The solvent was evaporated under reduced pressure and the obtained residue was purified by silica gel column chromatography (eluent solvent; hexane:ethyl acetate=2:1) to prepare 0.0700 g (yield 69%) of a target compound.



1H-NMR (CDCl3, ppm) δ 2.64 (3H, s), 3.79 (1H, broad-s), 7.56-7.60 (1H, m), 7.87-7.93 (2H, m), 8.14-8.15 (1H, m), 8.20-8.23 (1H, m), 9.60 (1H, s).


<6-3>


Preparation of N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-6-(N-methylbenzamide)picolinamide (Compound No. 17-1103)



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According to the method of 1-7 of Example 1, a target compound was prepared from N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-6-(methylamino)picolinamide.



1H-NMR (CDCl3, ppm) δ 3.65 (3H, s), 7.28-7.41 (6H, m), 7.77 (1H, t, J=7.8 Hz), 7.91 (1H, s), 8.00-8.02 (1H, m), 8.14 (1H, s), 9.39 (1H, s).


Example 7
Preparation of N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-2-(2-fluoro-N-methylbenzamide)thiazole-4-carboxamide (Compound No. 27-628)



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<7-1>


Preparation of 2-aminothiazole-4-carboxylic acid



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To 40 ml of an aqueous solution of 4.00 g (23.2 mmol) of ethyl 2-aminothiazole-4-carboxylate was added 1.86 g (46.5 mmol) of sodium hydroxide, followed by stirring at room temperature for 5 hours. The reaction liquid was adjusted to pH 1 by the addition of concentrated hydrochloric acid, and the precipitated crystals were collected by filtration to prepare 2.84 g (yield 85%) of a target compound.



1H-NMR (CDCl3, ppm) δ 7.18 (2H, broad-s), 7.38 (1H, s).


The proton of the carboxylic acid was not detected.


<7-2>


Preparation of 2-chlorothiazole-4-carboxylic acid



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To a solution of 2.84 g (19.7 mmol) of 2-aminothiazole-4-carboxylic acid in 30 ml of 1,4-dioxane was added 50 ml of concentrated hydrochloric acid, followed by cooling to 0° C., and 10 ml of an aqueous solution of 2.04 g (29.6 mmol) of sodium nitrite was added charged dropwise thereto at 0° C. to 5° C. The reaction liquid was stirred at 0° C. for 2 hours, and then 2.93 g (29.6 mmol) of copper chloride was charged in separate portions thereto. The reaction liquid was returned to room temperature, followed by stirring for 8 hours. To the reaction liquid were added water and ethyl acetate, followed by extraction with ethyl acetate four times. The organic layer was washed with saturated brine, and then dried over anhydrous magnesium sulfate. The solvent was evaporated under reduced pressure to prepare 1.77 g (yield 55%) of a target compound.



1H-NMR (DMSO-d6, ppm) δ 8.41 (1H, s).


The proton of the carboxylic acid was not detected.


<7-3>


Preparation of N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-2-chlorothiazole-4-carboxamide



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According to the method of 4-3 of Example 4, a target compound was prepared from 2-chlorothiazole-4-carbonylchloride prepared from 2-chlorothiazole-4-carboxylic acid and thionyl chloride, and 2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)aniline obtained in 1-2 of Example 1.



1H-NMR (CDCl3, ppm) δ 7.91 (1H, s), 8.13 (1H, s), 8.19 (1H, s), 8.82 (1H, s).


<7-4>


Preparation of N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-2-(methylamino)thiazole-4-carboxamide



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According to the method of 6-2 of Example 6, a target compound was prepared from N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-2-chlorothiazole-4-carboxamide.



1H-NMR (CDCl3, ppm) δ 3.03 (3H, s), 5.11-5.12 (1H, m), 7.50 (1H, s), 7.88 (1H, s), 8.11 (1H, s), 8.99 (1H, s).


<7-5>


Preparation of N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-2-(2-fluoro-N-methylbenzamide)thiazole-4-carboxamide (Compound No. 27-628)



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According to the method of 1-7 of Example 1, a target compound was prepared from N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-2-(methylamino)thiazole-4-carboxamide and 2-fluorobenzoyl chloride.



1H-NMR (CDCl3, ppm) δ 3.67 (3H, s), 6.99-7.24 (1H, m), 7.29-7.35 (1H, m), 7.52-7.59 (2H, m), 7.90 (1H, s), 8.06 (1H, s), 8.14 (1H, s), 9.08 (1H, s).


Example 8
Preparation of 2,2,2-trichloroethyl 2-fluoro-3-(2-iodo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl(methyl)carbamate (Compound No. 12-864)



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<8-1>


Preparation of 4-(perfluorobutan-2-yl)-2-(trifluoromethyl)aniline



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According to the method of 1-1 of Example 1, a target compound was prepared from 2-(trifluoromethyl)aniline and nonafluoro-s-butyliodide under the light-shielding reaction condition.



1H-NMR (CDCl3, ppm) δ 4.49 (2H, broad-s), 6.81 (1H, d, J=8.8 Hz), 7.47 (1H, d, J=8.8 Hz), 7.61 (1H, s).


<8-2>


Preparation of 2-iodo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)aniline



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To 100 mL of ethanol was added 17.0 g (44.8 mmol) of 4-(perfluorobutan-2-yl)-2-(trifluoromethyl)aniline, and 5.28 g (53.8 mmol) of concentrated sulfuric acid and 12.6 g (55.8 mmol) of N-iodosuccinimide were added thereto under ice-cooling, followed by stirring at room temperature for 1 hour and 30 minutes and at 40° C. for 4 hours. To the reaction solution was added a 4 M aqueous sodium hydroxide solution to neutralize the reaction solution, and then ethyl acetate was added thereto to extract the organic phase. The organic phase was washed with saturated brine, and dried over anhydrous magnesium sulfate, and then the solvent was evaporated under reduced pressure. The obtained residue was purified by silica gel column chromatography (eluent solvent; hexane:ethyl acetate=10:1) to prepare 14.6 g (yield 65%) of a target compound.



1H-NMR (CDCl3, ppm) δ 5.04 (2H, broad-s), 7.62 (1H, s), 7.97 (1H, s).


<8-3>


Preparation of 2-chloro-N-(2-iodo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenyl)-3-nitrobenzamide



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According to the method of 4-3 of Example 4, a target compound was prepared from 2-iodo-4-(perfluorobutan-2-yl)-6-(trifluormethyl)aniline.



1H-NMR (CDCl3, ppm) δ 7.60-7.61 (1H, m), 7.77 (1H, s), 7.89-7.96 (2H, m), 8.03-8.04 (1H, m), 8.38 (1H, s).


<8-4>


Preparation of 2-fluoro-N-(2-iodo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenyl)-3-nitrobenzamide



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According to the method of 1-4 of Example 1, a target compound was prepared from 2-chloro-N-(2-iodo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenyl)-3-nitrobenzamide.



1H-NMR (CDCl3, ppm) δ 7.53-7.54 (1H, m), 7.95 (1H, s), 8.24-8.32 (2H, m), 8.36 (1H, s), 8.44-8.48 (1H, m).


<8-5>


Preparation of 3-amino-2-fluoro-N-(2-iodo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenyl)benzamide



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According to the method of 1-5 of Example 1, a target compound was prepared from 2-fluoro-N-(2-iodo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenyl)-3-nitrobenzamide.



1H-NMR (CDCl3, ppm) δ 3.93 (2H, broad-s), 7.02-7.03 (1H, m), 7.11-7.13 (1H, m), 7.47-7.51 (1H, m), 7.92 (1H, s), 8.31-8.34 (2H, m).


<8-6>


Preparation of 2-fluoro-N-(2-iodo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenyl)-3-(methylamino)benzamide



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According to the method of 1-6 of Example 1, a target compound was prepared from 3-amino-2-fluoro-N-(2-iodo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenyl)benzamide.



1H-NMR (CDCl3, ppm) δ 2.95-2.96 (3H, m), 4.15 (1H, broad-s), 6.91-6.93 (1H, m), 7.19-7.20 (1H, m), 7.38-7.42 (1H, m), 7.92 (1H, s), 8.32 (1H, d, J=14.1 Hz), 8.34 (1H, s).


<8-7>


Preparation of 2,2,2-trichloroethyl 2-fluoro-3-(2-iodo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl(methyl)carbamate (Compound No. 12-864)



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According to the method of 1-7 of Example 1, a target compound was prepared from 2-fluoro-N-(2-iodo-4-(perfluorobutan-2-yl)-6-(trifluoromethyl)phenyl)-3-(methylamino)benzamide and 2,2,2-trichloroethoxycarbonylchloride.



1H-NMR (CDCl3, ppm) δ 3.40 (3H, s), 4.74 (2H, broad-s), 7.37 (1H, t, J=7.8 Hz), 7.52-7.58 (1H, m), 7.93 (1H, s), 8.12-8.15 (1H, m), 8.28-8.34 (2H, m).


Example 9
Preparation of N-(2-chloro-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-4-cyano-3-(4-cyano-N-methylbenzamide)benzamide (Compound No. 2-491)



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<9-1>


Preparation of 2-chloro-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)aniline



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According to the method of 1-2 of Example 1, a target compound was prepared from 4-(perfluoropropan-2-yl)-2-(trifluoromethyl)aniline obtained in 1-1 of Example 1 and N-chlorosuccinimide.



1H-NMR (CDCl3, ppm) δ 4.97 (2H, broad-s), 7.57 (1H, s), 7.64 (1H, s).


<9-2>


Preparation of N-(2-chloro-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-4-iodo-3-nitrobenzamide



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According to the method of 1-3 of Example 1, a target compound was prepared from 4-iodo-3-nitrobenzoyl chloride prepared from 4-iodo-3-nitrobenzoic acid and thionyl chloride, and 2-chloro-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)aniline.



1H-NMR (CDCl3, ppm) δ 7.52-7.81 (2H, m), 7.89 (1H, s), 8.00 (1H, s), 8.25 (1H, d, J=8.3 Hz), 8.38 (1H, d, J=1.9 Hz).


<9-3>


Preparation of 3-amino-N-(2-chloro-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-4-iodobenzamide



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According to the method of 1-5 of Example 1, a target compound was prepared from N-(2-chloro-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-4-iodo-3-nitrobenzamide.



1H-NMR (CDCl3, ppm) δ 4.35 (2H, s), 6.92 (1H, dd, J=1.9, 8.3 Hz), 7.29 (1H, d, J=1.9 Hz), 7.60 (1H, s), 7.79 (1H, d, J=8.3 Hz), 7.86 (1H, s), 7.97 (1H, s).


<9-4>


Preparation of N-(2-chloro-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-4-iodo-3-(methylamino)benzamide



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According to the method of 1-6 of Example 1, a target compound was prepared from 3-amino-N-(2-chloro-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-4-iodobenzamide.



1H-NMR (CDCl3, ppm) δ 2.97 (3H, s), 4.46 (1H, broad-s), 6.89 (1H, dd, J=1.9, 8.3 Hz), 7.07 (1H, d, J=1.9 Hz), 7.65 (1H, s), 7.80 (1H, d, J=8.3 Hz), 7.86 (1H, s), 7.97 (1H, s).


<9-5>


Preparation of N-(2-chloro-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-4-cyano-3-(methylamino)benzamide



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To 10 mL of DMF were added 0.350 g (0.560 mmol) of N-(2-chloro-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-4-iodo-3-(methylamino)benzamide and 0.200 g (2.25 mmol) of copper (I) cyanide, followed by stirring at 140° C. for 1 hour and 30 minutes. A saturated aqueous sodium thiosulfate solution was poured into the reaction solution to quench the reaction, and the organic layer was collected with ethyl acetate and washed with saturated brine. The organic layer was dried over anhydrous magnesium sulfate, and then the solvent was evaporated under reduced pressure. The obtained residue was purified by silica gel column chromatography (eluent solvent; hexane:ethyl acetate=5:1→3:1) to prepare 0.250 g (yield 86%) of a target compound.



1H-NMR (CDCl3, ppm) δ 3.01 (1/2*3H, s), 3.03 (1/2*3H, s), 4.89 (1/2*1H, s), 4.90 (1/2*1H, s), 7.80 (1H, dd, J=1.5, 8.3 Hz), 7.21-7.22 (1H, m), 7.54 (1H, d, J=8.3 Hz), 7.67 (1H, s), 7.88 (1H, s), 7.99 (1H, s).


<9-6>


Preparation of N-(2-chloro-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-4-cyano-3-(4-cyano-N-methylbenzamide)benzamide (Compound No. 2-491)



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According to the method of 1-7 of Example 1, a target compound was prepared from N-(2-chloro-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-4-cyano-3-(methylamino)benzamide and 4-cyanobenzoylchloride.



1H-NMR (CDCl3, ppm) δ 3.81 (3H, broad-s), 7.52-7.84 (8H, m), 7.89 (1H, s), 8.00 (1H, s).


Example 10
Preparation of N-(3-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)-6-cyano-2-fluorophenyl)-6-chloronicotinamide (Compound No. 1-1968)



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<10-1>


Preparation of N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-4-cyano-2,3-difluorobenzamide



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To a solution of 0.840 g (4.59 mmol) of 4-cyano-2,3-difluorobenzoic acid in 10 ml of dichloromethane were added one drop of DMF and 0.470 ml (5.51 mmol) of oxalyl chloride, followed by stirring at room temperature for 1 hour. The solvent was evaporated under reduced pressure and the obtained 4-cyano-2,3-difluorobenzoyl chloride was added to a solution of 1.56 g (3.83 mmol) of 2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)aniline obtained in 1-2 of Example 1 in 5 ml of DMI, followed by stirring at 130° C. for 5 hours. To the reaction liquid were added water and ethyl acetate, and the organic layer was washed with a saturated aqueous sodium hydrogen carbonate solution and saturated brine, and then dried over anhydrous magnesium sulfate. The solvent was evaporated under reduced pressure and the obtained residue was purified by silica gel column chromatography (eluent solvent; hexane:ethyl acetate=1:0-+10:1) to prepare 0.58 g (yield 27%) of a target compound.



1H-NMR (CDCl3, ppm) δ 7.52-7.62 (1H, m), 7.92-7.94 (1H, m), 8.02-8.06 (1H, m), 8.13-8.16 (2H, m).


<10-2>


Preparation of 3-amino-N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-4-cyano-2-fluorobenzamide



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To a solution of N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-4-cyano-2,3-difluorobenzamide in 5 ml of DMSO was added 49.0 mg of ammonium carbonate, followed by stirring 100° C. for 5 hours. To the reaction liquid were added water and ethyl acetate, and the organic layer was washed with water, and then and dried over anhydrous magnesium sulfate. The solvent was evaporated under reduced pressure and the obtained residue was purified by silica gel column chromatography (eluent solvent; hexane:ethyl acetate=8:1→4:1) to prepare 0.30 g (yield 51%) of a target compound.



1H-NMR (CDCl3, ppm) δ 4.71 (2H, broad-s), 7.35-7.39 (1H, m), 7.40-7.44 (1H, m), 7.92 (1H, s), 8.12-8.15 (2H, m).


<10-3>


Preparation of N-(3-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)-6-cyano-2-fluorophenyl)-6-chloronicotinamide (Compound No. 1-1968)



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To a solution of 0.0500 g (0.0877 mol) of 3-amino-N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-4-cyano-2-fluorobenzamide in 0.200 ml of DMI was added 0.0308 g (0.175 mmol) of 6-chloronicotinoylchloride, followed by stirring at 130° C. for 6 hours. To the reaction liquid were added water and ethyl acetate, and the organic layer was washed with 1 M hydrochloric acid, a saturated aqueous sodium hydrogen carbonate solution, and saturated brine, and then dried over anhydrous magnesium sulfate. The solvent was evaporated under reduced pressure and the obtained residue was purified by silica gel column chromatography (eluent solvent; hexane:ethyl acetate=2:1) to prepare 0.0100 g (yield 16%) of a target compound.



1H-NMR (CDCl3, ppm) δ 7.54 (1H, d, J=8.8 Hz), 7.72 (1H, d, J=8.8 Hz), 7.93 (1H, s), 8.09 (1H, s), 8.17-8.18 (2H, m), 8.27 (1H, dd, J=2.4 Hz 8.8 Hz), 8.38 (1H, d, J=10.8 Hz), 8.98 (1H, d, J=2.4 Hz).


Example 11
Preparation of 3-(4-cyanobenzamide)-N-(2,6-diiodo-4-(perfluorobutan-2-yl)phenyl)benzamide (Compound No. 6-79)



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<11-1>


Preparation of 2,6-diiodo-4-(perfluorobutan-2-yl)aniline



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According to the method of 3-1 of Example 3, a target compound was prepared from 4-(perfluorobutan-2-yl)aniline obtained in 4-1 of Example 4.



1H-NMR (CDCl3, ppm) δ 4.95 (2H, broad-s), 7.78 (2H, s).


<11-2>


Preparation of N-(2,6-diiodo-4-(perfluorobutan-2-yl)phenyl)-3-nitrobenzamide



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According to the method of 4-3 of Example 4, a target compound was prepared from 2,6-diiodo-4-(perfluorobutan-2-yl)aniline and 3-nitrobenzoyl chloride.



1H-NMR (CDCl3, ppm) δ 7.74 (1H, t, J=8.0 Hz), 8.11 (2H, s), 8.42 (1H, d, J=7.6 Hz), 8.46 (1H, d, J=8.4 Hz), 8.90 (1H, d, J=12.4 Hz), 8.92 (1H, s).


<11-3>


Preparation of 3-amino-N-(2,6-diiodo-4-(perfluorobutan-2-yl)phenyl)benzamide



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According to the method of 1-5 of Example 1, a target compound was prepared from N-(2,6-diiodo-4-(perfluorobutan-2-yl)phenyl)-3-nitrobenzamide.



1H-NMR (CDCl3, ppm) δ 5.39 (2H, broad-s), 6.89-6.93 (1H, m), 7.29-7.31 (3H, m), 7.68 (1H, s), 8.08 (2H, s).


<11-4>


Preparation of 3-(4-cyanobenzamide)-N-(2,6-diiodo-4-(perfluorobutan-2-yl)phenyl)benzamide (Compound No. 6-79)



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According to the method of 1-7 of Example 1, a target compound was prepared from 3-amino-N-(2,6-diiodo-4-(perfluorobutan-2-yl)phenyl)benzamide and 4-cyanobenzoylchloride.



1H-NMR (CDCl3, ppm) δ 7.58 (1H, t, J=8.2 Hz), 7.79-7.83 (3H, m), 7.97 (2H, s), 8.01 (2H, d, J=8.0 Hz), 8.09 (2H, s), 8.18 (1H, s), 8.29 (1H, s).


Example 12
Preparation of N-(3-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethoxy)phenylcarbamoyl)-2-fluorophenyl)-2-chloronicotinamide (Compound No. 6-5908)



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<12-1>


Preparation of 4-(perfluoropropan-2-yl)-2-(trifluoromethoxy)aniline



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According to the method of 1-1 of Example 1, a target compound was prepared from 2-trifluoromethoxy aniline.



1H-NMR (CDCl3, ppm) δ 4.19 (2H, broad-s), 6.86 (1H, d, J=8.8 Hz), 7.30 (1H, d, J=8.8 Hz), 7.36 (1H, s).


<12-2>


Preparation of 2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethoxy)aniline



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According to the method of 1-2 of Example 1, a target compound was prepared from 4-(perfluoropropan-2-yl)-2-(trifluoromethoxy)aniline.



1H-NMR (CDCl3, ppm) δ 4.65 (2H, broad-s), 7.33 (1H, s), 7.71 (1H, s).


<12-3>


Preparation of N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethoxy)phenyl)-2-chloro-3-nitrobenzamide



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According to the method of 1-3 of Example 1, a target compound was prepared from 2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethoxy)aniline.



1H-NMR (CDCl3, ppm) δ 7.49-7.61 (3H, m), 7.80-7.96 (3H, m).


<12-4>


Preparation of N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethoxy)phenyl)-2-fluoro-3-nitrobenzamide



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According to the method of 1-4 of Example 1, a target compound was prepared from N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethoxy)phenyl)-2-chloro-3-nitrobenzamide.



1H-NMR (CDCl3, ppm) δ 7.53 (1H, t, J=7.8 Hz), 7.60 (1H, broad-s), 7.89 (1H, d, J=1.5 Hz), 8.07 (1H, broad-d, J=12.7 Hz), 8.29-8.30 (1H, m), 8.43-8.47 (1H, m).


<12-5>


Preparation of 3-amino-N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethoxy)phenyl)-2-fluorobenzamide



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According to the method of 1-5 of Example 1, a target compound was prepared from N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethoxy)phenyl)-2-fluoro-3-nitrobenzamide.



1H-NMR (CDCl3, ppm) δ 3.92 (2H, broad-s), 6.99-7.04 (1H, m), 7.11 (1H, t, J=7.8 Hz), 7.45-7.49 (1H, m), 7.57 (1H, broad-s), 7.87 (1H, d, J=2.0 Hz), 8.14 (1H, d, J=14.2 Hz).


<12-6>


Preparation of N-(3-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethoxy)phenylcarbamoyl)-2-fluorophenyl)-2-chloronicotinamide (Compound No. 6-5908)



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According to the method of 1-7 of Example 1, a target compound was prepared from 3-amino-N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethoxy)phenyl)-2-fluorobenzamide and 2-chloronicotinoylchloride.



1H-NMR (CDCl3, ppm) δ 7.39-7.49 (2H, m), 7.59 (1H, s), 7.88-7.94 (2H, m), 8.07 (1H, d, J=12.2 Hz), 8.31-8.33 (1H, m), 8.57-8.58 (1H, m), 8.60-8.70 (1H, m), 8.74 (1H, broad-s).


Example 13
Preparation of 3-benzamide-N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-4-fluorobenzamide (Compound No. 6-3348)



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<13-1>


Preparation of N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-4-fluoro-3-nitrobenzamide



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According to the method of 1-3 of Example 1, a target compound was prepared from 4-fluoro-3-nitrobenzoyl chloride prepared from 4-fluoro-3-nitrobenzoic acid and thionyl chloride, and 2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)aniline obtained in 1-2 of Example 1.



1H-NMR (CDCl3, ppm) δ 7.47-7.50 (1H, m), 7.92 (2H, d, J=5.9 Hz), 8.16 (1H, s), 8.23-8.28 (1H, m), 8.65-8.67 (1H, m).


<13-2>


Preparation of 3-amino-N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-4-fluorobenzamide



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According to the method of 1-5 of Example 1, a target compound was prepared from N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-4-fluoro-3-nitrobenzamide.


APCI-MS m/z (M+1): 546


<13-3>


Preparation of 3-benzamide-N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-4-fluorobenzamide (Compound No. 6-3348)



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According to the method of 1-7 of Example 1, a target compound was prepared from 3-amino-N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-4-fluorobenzamide.



1H-NMR (CDCl3, ppm) δ 7.29-7.34 (1H, m), 7.53-7.65 (3H, m), 7.80-7.84 (1H, m), 7.90-7.92 (3H, m), 8.14 (1H, broad-s), 8.20 (1H, d, J=2.9 Hz), 8.25 (1H, broad-s), 9.10 (1H, dd, J=1.9, 7.3 Hz).


Example 14
Preparation of 2-chloro-N-(3-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)nicotinamide (Compound No. 6-460)



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<14-1>


Preparation of 2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)aniline



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According to the method of 8-2 of Example 8, a target compound was prepared from 4-(perfluoropropan-2-yl)-2-(trifluoromethyl)aniline obtained in 1-1 of Example 1 and N-iodosuccinimide.



1H-NMR (CDCl3, ppm) δ 5.04 (2H, broad-s), 7.64 (1H, s), 7.99 (1H, s).


<14-2>


Preparation of N-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-3-nitrobenzamide



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According to the method of 4-3 of Example 4, a target compound was prepared from 2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)aniline and 3-nitrobenzoyl chloride.



1H-NMR (CDCl3, ppm) δ 7.76-7.80 (2H, m), 7.97 (1H, s), 8.28, 8.30 (1H, m), 8.37 (1H, s), 8.49-8.52 (1H, m), 8.78 (1H, s).


<14-3>


Preparation of 3-amino-N-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)benzamide



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According to the method of 1-5 of Example 1, a target compound was prepared from N-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-3-nitrobenzamide.



1H-NMR (CDCl3, ppm) δ 3.89 (2H, broad-s), 6.89-6.92 (1H, m), 7.23-7.32 (3H, m), 7.68 (1H, s), 7.93 (1H, s), 8.34-8.36 (1H, m).


<14-4>


Preparation of 2-chloro-N-(3-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)nicotinamide (Compound No. 6-460)



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According to the method of 1-7 of Example 1, a target compound was prepared from 3-amino-N-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)benzamide and 2-chloronicotinoylchloride.



1H-NMR (CDCl3, ppm) δ 7.43-7.46 (1H, m), 7.58 (1H, t, J=7.8 Hz), 7.77 (1H, d, J=7.8 Hz), 7.91-7.95 (2H, m), 8.01 (1H, s), 8.24 (1H, dd, J=2.0, 7.8 Hz), 8.28 (1H, s), 8.36 (1H, s), 8.41 (1H, s), 8.54-8.56 (1H, m).


Example 15
Preparation of 2-fluoro-3-(4-fluoro-N-methylbenzamide)-N-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)benzamide (Compound No. 7-1733)



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<15-1>


Preparation of 2-chloro-N-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-3-nitrobenzamide



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According to the method of 4-3 of Example 4, a target compound was prepared from 2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)aniline obtained in 14-1 of Example 14 and 2-chloro-3-nitrobenzoyl chloride.



1H-NMR (CDCl3, ppm) δ 7.60 (1H, t, J=7.8 Hz), 7.76 (1H, s), 7.94 (1H, dd, J=1.5, 7.8 Hz), 7.97 (1H, s), 8.03 (1H, dd, J=1.5, 7.8 Hz), 8.39 (11, s).


<15-2>


Preparation of 2-fluoro-N-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-3-nitrobenzamide



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According to the method of 1-4 of Example 1, a target compound was prepared from 2-chloro-N-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-3-nitrobenzamide.



1H-NMR (CDCl3, ppm) δ 7.51-7.55 (1H, m), 7.97 (1H, s), 8.23 (1H, d, J=12.2 Hz), 8.28-8.32 (1H, m), 8.37 (1H, s), 8.44-8.48 (1H, m).


<15-3>


Preparation of 3-amino-2-fluoro-N-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)benzamide



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According to the method of 1-5 of Example 1, a target compound was prepared from 2-fluoro-N-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-3-nitrobenzamide.



1H-NMR (CDCl3, ppm) δ 3.92 (2H, broad-s), 7.02-7.04 (1H, m), 7.11 (1H, t, J=7.8 Hz), 7.47-7.52 (1H, m), 7.94 (1H, s), 8.30-8.35 (2H, m).


<15-4>


Preparation of 2-fluoro-N-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-3-(methylamino)benzamide



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According to the method of 1-6 of Example 1, a target compound was prepared from 3-amino-2-fluoro-N-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)benzamide.



1H-NMR (CDCl3, ppm) δ 2.95 (3H, s), 4.15 (1H, broad-s), 6.90 (1H, t, J=8.2 Hz), 7.19 (1H, t, J=7.8 Hz), 7.40 (1H, t, J=7.8 Hz), 7.92 (1H, s), 8.30 (1H, s), 8.34 (1H, s).


<15-5>


Preparation of 2-fluoro-3-(4-fluoro-N-methylbenzamide)-N-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)benzamide (Compound No. 7-1733)



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According to the method of 1-7 of Example 1, a target compound was prepared from 2-fluoro-N-(2-iodo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-3-(methylamino)benzamide and 4-fluorobenzoyl chloride.



1H-NMR (CDCl3, ppm) δ 3.50 (3H, s), 6.91 (2H, s), 6.93-7.35 (3H, m), 7.46 (1H, t, J=7.0 Hz), 7.93 (1H, s), 8.01-8.10 (1H, m), 8.13 (1H, broad-s), 8.34 (1H, s).


Example 16
Preparation of N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-2-fluoro-N-methyl-3-(N-methylbenzamide)benzamide (Compound No. 9-2164)



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To a solution of 0.100 g (0.150 mmol) of N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-2-fluoro-3-(N-methylbenzamide)benzamide obtained in 1-7 of Example 1 in 5 ml of DMF was added 0.00900 g (0.230 mmol) of sodium hydride (60% in oil), followed by stirring at room temperature for 40 minutes. To the reaction liquid was added 0.0300 g (0.180 mmol) of methyl iodide, followed by stirring at the same temperature for 6 hours. To the reaction liquid were added water and ethyl acetate, and the organic layer was washed with water and saturated brine, and dried over anhydrous magnesium sulfate. The solvent was evaporated under reduced pressure and the obtained residue was purified by silica gel column chromatography (eluent solvent; hexane:ethyl acetate=4:1) to prepare 0.106 g of a target compound quantitatively.



1H-NMR (CDCl3, ppm) δ 2.18-2.19 (3H, m), 3.48 (3H, s), 7.21-7.25 (4H, m), 7.32-7.40 (4H, m), 7.92 (1H, s), 8.13 (1H, s).


Example 17
Preparation of N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-3-(4-cyanobenzamide)-N-methylbenzamide (Compound No. 8-289)



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<17-1>


Preparation of N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-3-nitrobenzamide



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According to the method of 4-3 of Example 4, a target compound was prepared from 2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)aniline obtained in 1-2 of Example 1 and 3-nitrobenzoyl chloride.



1H-NMR (CDCl3, ppm) δ 7.75-7.79 (2H, m), 7.94 (1H, s), 8.17 (1H, d, J=1.0 Hz), 8.28 (1H, dd, J=1.5, 7.8 Hz), 8.48-8.51 (1H, m), 8.76-8.77 (1H, m).


<17-2>


Preparation of N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-N-methyl-3-nitrobenzamide



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According to the method of Example 16, a target compound was prepared from N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-3-nitrobenzamide.



1H-NMR (CDCl3, ppm) δ 3.28 (1/2*3H, s), 3.44 (1/2*3H, s), 7.41 (1/2*1H, t, J=7.8 Hz), 7.71-7.76 (2/2*1H, m), 7.84 (1/2*1H, s), 7.93-7.95 (1/2*1H, m), 7.98 (1/2*1H, s), 8.07-8.09 (2/2*1H, m), 8.14-8.16 (1/2*1H, m), 8.19 (1/2*1H, s), 8.39-8.41 (1/2*1H, m), 8.45-8.46 (1/2*1H, m).


<17-3>


Preparation of 3-amino-N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-N-methylbenzamide



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According to the method of 1-5 of Example 1, a target compound was prepared from N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-N-methyl-3-nitrobenzamide.



1H-NMR (CDCl3, ppm) δ 3.24 (3/4*3H, s), 3.37 (1/4*3H, s), 3.80 (2H, broad-s), 6.47 (1/4*1H, d, J=7.8 Hz), 6.54-6.57 (1/4*1H, m), 6.78-6.84 (5/4*1H, m), 6.86 (3/4*11H, t, J=2.0 Hz), 6.96 (3/4*1H, d, J=7.8 Hz), 7.23-7.27 (3/4*1H, m), 7.79 (1/4*1H, s), 7.94 (3/4*1H, s), 8.00 (1/4*1H, s), 8.15 (3/4*1H, s).


<17-4>


Preparation of N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-3-(4-cyanobenzamide)-N-methylbenzamide (Compound No. 8-289)



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According to the method of 1-7 of Example 1, a target compound was prepared from 3-amino-N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-N-methylbenzamide and 4-cyanobenzoylchloride.



1H-NMR (CDCl3, ppm) δ 3.26 (2/3*3H, s), 3.38 (1/3*3H, s), 7.08-7.09 (1/3*1H, m), 7.12-7.14 (1/3*1H, m), 7.32 (2/3*1H, d, J=7.8 Hz), 7.45-7.49 (3/3*1H, m), 7.72-7.76 (9/3*1H, m), 7.83 (1/3*1H, s), 7.85-7.89 (4/3*1H, m), 7.95 (2/3*1H, s), 7.98-8.00 (4/3*1H, m), 8.04 (2/3*1H, d, J=6.3 Hz), 8.16 (2/3*1H, s), 8.57 (2/3*1H, s).


Example 18
Preparation of 3-benzamide-N-(2-bromo-4-(perfluoroethyl)-6-(trifluoromethyl)phenyl)benzamide (Compound No. 6-5913)



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<18-1>


Preparation of 4-(perfluoroethyl)-2-(trifluoromethyl)aniline



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To 40 ml of an aqueous solution of 7.04 g (40.4 mmol) of 85% sodium hydrosulfite and 3.40 g (40.4 mmol) of sodium hydrogen carbonate were added 13.6 g (33.7 mmol) of 2-(trifluoromethyl)aniline and 40 ml of DMF. To this reaction liquid was added 50 ml of a solution of 11.2 g (45.5 mmol) of 1,1,2,2,2-pentafluoroethyliodide in DMF (DMF was cooled to −30° C., and 1,1,2,2,2-pentafluoroethyl iodide was dissolved therein), and placed in an autoclave, followed by stirring at 110° C. for 9 hours. After being left to stand at room temperature overnight, water and ethyl acetate were added to the reaction liquid, followed by extraction with ethyl acetate. The organic layer was washed with water, a saturated aqueous sodium hydrogen carbonate solution, and saturated brine. The organic layer was dried over anhydrous sodium sulfate, then the solvent was evaporated under reduced pressure, and the obtained residue was purified by silica gel column chromatography (eluent solvent; hexane:ethyl acetate=10:1→5:1) to prepare 1.95 g (yield 21%) of a target compound.



1H-NMR (CDCl3, ppm) δ 4.53 (2H, broad-s), 6.81 (1H, d, J=8.3 Hz), 7.48 (1H, d, J=8.3 Hz), 7.63 (1H, broad-s).


<18-2>


Preparation of 2-bromo-4-(perfluoroethyl)-6-(trifluoromethyl)aniline



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According to the method of 1-2 of Example 1, a target compound was prepared from 4-(perfluoroethyl)-2-(trifluoromethyl)aniline.



1H-NMR (CDCl3, ppm) δ 5.08 (2H, broad-s), 7.62 (1H, s), 7.80 (1H, s).


<18-3>


Preparation of N-(2-bromo-4-(perfluoroethyl)-6-(trifluoromethyl)phenyl)-3-nitrobenzamide



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To a solution of 2.50 g (6.99 mmol) of 2-bromo-4-(perfluoroethyl)-6-(trifluoromethyl)aniline in 20 ml of pyridine was added 2.72 g (14.7 mmol) of 3-nitrobenzoyl chloride, followed by stirring at 100° C. for 12 hours. To the reaction liquid were added water and ethyl acetate, followed by extraction with ethyl acetate. The organic layer was washed with 1 M hydrochloric acid, a saturated aqueous sodium hydrogen carbonate solution, and saturated brine. The organic layer was dried over anhydrous sodium sulfate, and then the solvent was evaporated under reduced pressure. To the obtained residue were added THF and an aqueous sodium hydroxide solution, followed by stirring at room temperature for 8 hours. The reaction liquid was extracted/dried in the same manner as described above, and the solvent was evaporated under reduced pressure. The obtained residue was purified by silica gel column chromatography (eluent solvent; hexane:ethyl acetate=7:1-5:1) to prepare 0.202 g (yield 6%) of a target compound.



1H-NMR (CDCl3, ppm) δ 7.75 (1H, s), 7.78 (1H, t, J=7.8 Hz), 7.94 (1H, s), 8.17 (1H, s), 8.29-8.30 (1H, m), 8.50-8.52 (1H, m), 8.78 (1H, t, J=2.0 Hz).


<18-4>


Preparation of 3-amino-N-(2-bromo-4-(perfluoroethyl)-6-(trifluoromethyl)phenyl)benzamide



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According to the method of 1-5 of Example 1, a target compound was prepared from N-(2-bromo-4-(perfluoroethyl)-6-(trifluoromethyl)phenyl)-3-nitrobenzamide.



1H-NMR (CDCl3, ppm) δ 3.89 (2H, broad-s), 6.90-6.92 (1H, m), 7.23-7.32 (3H, m), 7.64 (1H, s), 7.90 (1H, s), 8.13 (1H, s).


<18-5>


Preparation of 3-benzamide-N-(2-bromo-4-(perfluoroethyl)-6-(trifluoromethyl)phenyl)benzamide (Compound No. 6-5913)



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According to the method of 1-7 of Example 1, a target compound was prepared from 3-amino-N-(2-bromo-4-(perfluoroethyl)-6-(trifluoromethyl)phenyl)benzamide.



1H-NMR (CDCl3, ppm) δ 7.51-7.62 (4H, m), 7.72 (1H, dd, J=1.5, 7.8 Hz), 7.89-8.00 (6H, m), 8.14 (1H, s), 8.27 (1H, t, J=2.0 Hz).


Example 19
Preparation of 3-benzamide-N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-4-cyanobenzamide (Compound No. 1-627)



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<19-1>


Preparation of N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-4-fluoro-3-nitrobenzamide



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According to the method of 4-3 of Example 4, a target compound was prepared from 4-fluoro-3-nitrobenzoyl chloride prepared from 4-fluoro-3-nitrobenzoic acid and thionyl chloride, and 2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)aniline obtained in 1-2 of Example 1.



1H-NMR (CDCl3, ppm) δ 7.47-7.50 (1H, m), 7.92 (2H, d, J=5.9 Hz), 8.16 (1H, s), 8.23-8.28 (1H, m), 8.65-8.67 (1H, m).


<19-2>


Preparation of N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-4-cyano-3-nitrobenzamide



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To a solution of 0.500 g (0.870 mmol) of N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-4-fluoro-3-nitrobenzamide in 5 ml of DMF was added 0.0639 g (1.31 mmol) of sodium cyanide, followed by stirring at room temperature for 10 hours. To the reaction liquid were added water and ethyl acetate, followed by extraction with ethyl acetate. The organic layer was washed with a 10% aqueous sodium hydroxide solution and saturated brine. The organic layer was dried over anhydrous sodium sulfate, and then the solvent was evaporated under reduced pressure. The obtained residue was purified by silica gel column chromatography to prepare 0.0500 g (yield 10%) of a target compound.



1H-NMR (CDCl3, ppm) δ 7.80 (1H, s), 7.96 (1H, s), 8.12-8.14 (1H, m), 8.18 (1H, s), 8.36 (1H, dd, J=2.0, 8.3 Hz), 8.84 (1H, d, J=1.5 Hz).


<19-3>


Preparation of 3-amino-N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-4-cyanobenzamide



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According to the method of 1-5 of Example 1, a target compound was prepared from N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-4-cyano-3-nitrobenzamide.



1H-NMR (CDCl3, ppm) δ 4.68 (2H, broad-s), 7.18 (1H, dd, J=1.9, 8.3 Hz), 7.29 (1H, s), 7.52-7.55 (1H, m), 7.68 (1H, s), 7.92 (1H, s), 8.14 (1H, d, J=1.5 Hz).


<19-4>


Preparation of 3-benzamide-N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-4-cyanobenzamide (Compound No. 1-627)



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According to the method of 1-7 of Example 1, a target compound was prepared from 3-amino-N-(2-bromo-4-(perfluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-4-cyanobenzamide.



1H-NMR (CDCl3, ppm) δ 7.56-7.59 (3H, m), 7.64-7.66 (1H, m), 7.80-7.87 (2H, m), 7.94-7.97 (2H, m), 8.16 (1H, s), 8.46 (1H, s), 8.57 (1H, s), 9.16 (1H, s).


Next, Preparation Examples in which the compound of the present invention is contained as an active ingredient will be shown, but the present invention is not limited thereto. Further, in Preparation Examples, parts represent parts by weight.


Preparation Example 1

20 parts of the compound represented by Formula (1) of the present invention, 10 parts of polyoxyethylene styrylphenyl ether, and 70 parts of xylene were mixed uniformly to obtain an emulsion.


Preparation Example 2

10 parts of the compound represented by Formula (1) of the present invention, 2 parts of sodium lauryl sulfate, 2 parts of dialkyl sulfosuccinate, 1 part of a 0-naphthalene sulfonic acid formalin condensate sodium salt, and 85 parts of diatomaceous earth were stirred and mixed uniformly to obtain a wettable powder.


Preparation Example 3

0.3 parts of the compound represented by Formula (1) of the present invention and 0.3 parts of white carbon were mixed uniformly, and 99.2 parts of clay and 0.2 parts of DRILESS A (manufactured by Sankyo Agro Co., Ltd.) were added thereto, followed by pulverizing and mixing uniformly, thereby obtaining powders.


Preparation Example 4

3 parts of the compound represented by Formula (1) of the present invention, 1.5 parts of a polyoxyethylene/polyoxypropylene condensate, 3 parts of carboxymethyl cellulose, 64.8 parts of clay, and 27.7 parts of talc were pulverized and mixed uniformly, and water was added thereto, followed by kneading, granulating, and drying, thereby obtaining powders.


Preparation Example 5

10 parts of the compound represented by Formula (1) of the present invention, 3 parts of a β-naphthalene sulfonic acid formalin condensate sodium salt, 1 part of tristyrylphenol, 5 parts of propylene glycol, 0.5 parts of a silicon-based defoaming agent, and 33.5 parts of water were sufficiently stirred and mixed, and then 0.3 parts of xanthan gum and 46.7 parts of water were mixed therewith, followed by stirring and mixing again, thereby obtaining a flowable Formulation.


Preparation Example 6

20 parts of the compound represented by Formula (1) of the present invention, 6 parts of a naphthalene sulfonic acid formaldehyde condensate metal salt, 1 part of dialkylsulfosuccinate metal salt, and 73 parts of calcium carbonate were pulverized and mixed uniformly, and water was added thereto, followed by kneading, granulating, and drying, thereby obtaining a granule wettable powder.


For the use of Formulations obtained above, Formulation was diluted to 1-fold to 10000-fold with water or was not diluted, and then directly sprayed.


Next, the usefulness of the compound of the present invention as a pest control agent will be described specifically with reference to the following Test Examples, but the present invention is not limited thereto.


Test Example 1

Pesticidal Test Against Spodoptera litura


A piece of a cabbage leaf was immersed for 30 seconds in a chemical solution in which a test compound had been prepared at a predetermined concentration, and air-dried, and then put into a 7 cm polyethylene cup having a filter paper laid on the bottom thereof, and 2-stage larvae of Spodoptera litura were released. They were left to stand in a thermostatic chamber at 25° C., and the numbers of the living pests and the dead pests were examined after 6 days. The test was carried out with five larvae per group in two replicates.


Further, the following compound (A) disclosed in the pamphlet of International Publication WO 2005/073165 was used as a comparative compound.




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As the results of the above tests, the compounds of Compound Nos. 1-470, 1-491, 1-513, 1-627, 1-1925, 2-491, 6-38, 6-39, 6-45, 6-46, 6-47, 6-57, 6-60, 6-71, 6-72, 6-78, 6-79, 6-80, 6-90, 6-93, 6-111, 6-147, 6-268, 6-269, 6-270, 6-271, 6-272, 6-288, 6-289, 6-290, 6-293, 6-300, 6-304, 6-306, 6-311, 6-346, 6-347, 6-348, 6-349, 6-366, 6-367, 6-368, 6-382, 6-389, 6-424, 6-425, 6-426, 6-427, 6-428, 6-444, 6-445, 6-446, 6-448, 6-449, 6-450, 6-452, 6-453, 6-460, 6-461, 6-467, 6-502, 6-503, 6-504, 6-505, 6-522, 6-523, 6-524, 6-538, 6-545, 6-804, 6-824, 6-825, 6-840, 6-1104, 6-1105, 6-1106, 6-1107, 6-1124, 6-1125, 6-1126, 6-1140, 6-1147, 6-1182, 6-1183, 6-1184, 6-1185, 6-1202, 6-1203, 6-1204, 6-1218, 6-1225, 6-1260, 6-1261, 6-1262, 6-1263, 6-1280, 6-1281, 6-1282, 6-1296, 6-1303, 6-1338, 6-1339, 6-1340, 6-1341, 6-1358, 6-1359, 6-1360, 6-1374, 6-1381, 6-1574, 6-1575, 6-1576, 6-1577, 6-1594, 6-1595, 6-1596, 6-1610, 6-1617, 6-1652, 6-1653, 6-1654, 6-1655, 6-1672, 6-1673, 6-1674, 6-1688, 6-1695, 6-1730, 6-1731, 6-1732, 6-1733, 6-1734, 6-1750, 6-1751, 6-1752, 6-1754, 6-1755, 6-1766, 6-1773, 6-1808, 6-1809, 6-1810, 6-1811, 6-1828, 6-1829, 6-1830, 6-1851, 6-2110, 6-3348, 6-3384, 6-5902, 6-5903, 6-5904, 6-5905, 6-5906, 6-5907, 6-5908, 6-5909, 6-5910, 6-5911, 6-5912, 7-38, 7-39, 7-45, 7-46, 7-47, 7-57, 7-60, 7-71, 7-72, 7-78, 7-79, 7-80, 7-90, 7-93, 7-132, 7-147, 7-268, 7-269, 7-270, 7-271, 7-285, 7-286, 7-288, 7-289, 7-290, 7-299, 7-300, 7-301, 7-303, 7-304, 7-305, 7-311, 7-346, 7-347, 7-348, 7-349, 7-366, 7-367, 7-368, 7-382, 7-389, 7-424, 7-425, 7-426, 7-427, 7-428, 7-444, 7-445, 7-446, 7-449, 7-460, 7-467, 7-502, 7-504, 7-505, 7-522, 7-523, 7-538, 7-804, 7-824, 7-825, 7-840, 7-948, 7-969, 7-984, 7-1104, 7-1105, 7-1106, 7-1107, 7-1124, 7-1125, 7-1126, 7-1140, 7-1147, 7-1182, 7-1183, 7-1184, 7-1185, 7-1202, 7-1203, 7-1204, 7-1218, 7-1225, 7-1260, 7-1261, 7-1262, 7-1263, 7-1280, 7-1281, 7-1282, 7-1296, 7-1303, 7-1338, 7-1339, 7-1340, 7-1341, 7-1358, 7-1359, 7-1360, 7-1374, 7-1381, 7-1417, 7-1574, 7-1575, 7-1576, 7-1577, 7-1594, 7-1595, 7-1596, 7-1605, 7-1606, 7-1608, 7-1610, 7-1616, 7-1617, 7-1638, 7-1639, 7-1645, 7-1652, 7-1672, 7-1673, 7-1730, 7-1731, 7-1732, 7-1733, 7-1750, 7-1751, 7-1752, 7-1764, 7-1766, 7-1773, 7-1794, 7-1808, 7-1809, 7-1810, 7-1811, 7-1828, 7-1829, 7-1844, 7-1851, 7-3348, 7-3369, 7-3384, 7-5902, 7-5903, 7-5904, 7-5905, 7-5906, 7-5907, 7-5910, 8-268, 8-288, 8-289, 8-304, 8-804, 8-824, 8-840, 9-270, 9-290, 9-291, 9-306, 9-2164, 9-2322, 11-777, 11-835, 12-777, 12-835, 12-864, 27-627, and 27-663 each showed a pesticidal rate of 70% or more at a concentration of 1 ppm.


Furthermore, the compounds of Compound Nos. 1-506, 1-1968, 2-513, 2-518, 6-454, 6-5913, 6-5914, 7-316, 7-5911, 7-5912, 7-5908, 7-5909, 17-1103, and 27-628 each showed a pesticidal rate of 70% or more at a concentration of 10 ppm.


Meanwhile, the compound (A) had a pesticidal rate of 50% or less at a concentration of 10 ppm.


Test Example 2

Pesticidal Test Against Plutella xylostella


A piece of a cabbage leaf was immersed for 30 seconds in a chemical solution in which a test compound had been prepared at a predetermined concentration, and air-dried, and then put into a 7 cm polyethylene cup having a filter paper laid on the bottom thereof, and 2-stage larvae of Plutella xylostella were released. They were left to stand in a thermostatic chamber at 25° C., and the numbers of the living pests and the dead pests were examined after 6 days. The test was carried out with five larvae per group in two replicates.


Further, the above compound (A) was used as a comparative compound.


As the results of the above tests, the compounds of Compound Nos. 1-491, 1-513, 1-627, 1-1925, 1-1968, 2-491, 2-513, 6-38, 6-39, 6-45, 6-46, 6-47, 6-57, 6-71, 6-72, 6-78, 6-79, 6-80, 6-90, 6-111, 6-147, 6-268, 6-270, 6-271, 6-272, 6-288, 6-289, 6-290, 6-293, 6-300, 6-304, 6-306, 6-346, 6-347, 6-348, 6-349, 6-366, 6-367, 6-368, 6-382, 6-389, 6-424, 6-425, 6-426, 6-427, 6-428, 6-444, 6-445, 6-446, 6-449, 6-450, 6-453, 6-460, 6-461, 6-467, 6-502, 6-503, 6-504, 6-505, 6-522, 6-523, 6-524, 6-538, 6-545, 6-804, 6-824, 6-825, 6-840, 6-1104, 6-1105, 6-1106, 6-1107, 6-1124, 6-1125, 6-1126, 6-1140, 6-1147, 6-1182, 6-1183, 6-1184, 6-1185, 6-1202, 6-1203, 6-1204, 6-1218, 6-1225, 6-1260, 6-1261, 6-1262, 6-1263, 6-1280, 6-1281, 6-1282, 6-1296, 6-1303, 6-1338, 6-1339, 6-1340, 6-1341, 6-1358, 6-1359, 6-1360, 6-1374, 6-1381, 6-1574, 6-1575, 6-1576, 6-1577, 6-1594, 6-1595, 6-1596, 6-1610, 6-1617, 6-1652, 6-1653, 6-1654, 6-1655, 6-1672, 6-1673, 6-1674, 6-1688, 6-1695, 6-1730, 6-1731, 6-1732, 6-1733, 6-1734, 6-1750, 6-1751, 6-1752, 6-1754, 6-1755, 6-1766, 6-1773, 6-1808, 6-1809, 6-1810, 6-1811, 6-1828, 6-1829, 6-1830, 6-1851, 6-2110, 6-3348, 6-3384, 6-5903, 6-5904, 6-5905, 6-5906, 6-5907, 6-5908, 6-5909, 6-5910, 6-5911, 6-5912, 7-38, 7-39, 7-45, 7-46, 7-47, 7-57, 7-60, 7-71, 7-72, 7-78, 7-79, 7-80, 7-90, 7-93, 7-132, 7-147, 7-268, 7-271, 7-286, 7-288, 7-289, 7-290, 7-299, 7-300, 7-301, 7-303, 7-304, 7-305, 7-311, 7-346, 7-347, 7-348, 7-349, 7-366, 7-367, 7-368, 7-382, 7-389, 7-424, 7-425, 7-426, 7-427, 7-428, 7-444, 7-445, 7-446, 7-449, 7-460, 7-467, 7-502, 7-504, 7-505, 7-522, 7-523, 7-538, 7-824, 7-840, 7-948, 7-969, 7-984, 7-1104, 7-1105, 7-1106, 7-1107, 7-1124, 7-1125, 7-1126, 7-1140, 7-1147, 7-1182, 7-1183, 7-1184, 7-1185, 7-1202, 7-1203, 7-1204, 7-1218, 7-1225, 7-1260, 7-1261, 7-1262, 7-1263, 7-1280, 7-1281, 7-1282, 7-1296, 7-1303, 7-1338, 7-1339, 7-1340, 7-1341, 7-1358, 7-1359, 7-1360, 7-1374, 7-1381, 7-1417, 7-1574, 7-1575, 7-1576, 7-1577, 7-1594, 7-1595, 7-1596, 7-1605, 7-1606, 7-1608, 7-1610, 7-1616, 7-1617, 7-1638, 7-1639, 7-1645, 7-1652, 7-1672, 7-1673, 7-1730, 7-1731, 7-1732, 7-1733, 7-1750, 7-1751, 7-1752, 7-1764, 7-1766, 7-1773, 7-1794, 7-1808, 7-1809, 7-1810, 7-1811, 7-1828, 7-1829, 7-1844, 7-1851, 7-3348, 7-3369, 7-3384, 7-5902, 7-5903, 7-5904, 7-5905, 7-5906, 7-5907, 7-5909, 7-5910, 8-268, 8-288, 8-289, 8-304, 8-824, 9-270, 9-290, 9-291, 9-306, 9-2164, 9-2322, 11-777, 11-835, 12-777, 12-835, and 12-864 each showed a pesticidal rate of 70% or more at a concentration of 1 ppm.


Furthermore, the compounds of Compound Nos. 1-470, 1-506, 2-518, 6-60, 6-93, 6-269, 6-311, 6-448, 6-452, 6-454, 6-5913, 6-5914, 7-269, 7-270, 7-285, 7-316, 7-804, 7-825, 7-5908, 7-5911, 7-5912, 8-804, 8-840, 17-1103, 27-627, 27-628, and 27-663 each showed a pesticidal rate of 70% or more at a concentration of 10 ppm.


Meanwhile, the compound (A) had a pesticidal rate of 50% or less at a concentration of 10 ppm.


Test Example 3

Pesticidal Test Against Adoxophyes honmai


A thinly sliced artificial feed was immersed for 30 seconds in a chemical solution in which a test compound had been prepared at a predetermined concentration, and air-dried, and then put into a 7 cm polyethylene cup having a filter paper laid on the bottom thereof, and 2-stage larvae of Adoxophyes honmai were released. They were left to stand in a thermostatic chamber at 25° C., and the numbers of the living pests and the dead pests were examined after 6 days. The test was carried out with five larvae per group in two replicates.


Further, the above compound (A) was used as a comparative compound.


As the results of the above tests, the compounds of Compound Nos. 6-72, 6-80, 6-90, 6-347, 6-348, 6-349, 6-366, 6-382, 6-427, 6-446, 6-449, 6-460, 6-503, 6-504, 6-505, 6-522, 6-524, 6-538, 6-1106, 6-1182, 6-1202, 6-1260, 6-1262, 6-1263, 6-1341, 6-1358, 6-1574, 6-1576, 6-1594, 6-1596, 6-1652, 6-1654, 6-1655, 6-1672, 6-1674, 6-1688, 6-1730, 6-1732, 6-1733, 6-1750, 6-1809, 6-1811, 6-1828, 6-1830, 7-348, 7-366, 7-382, 7-502, 7-505, 7-522, 7-538, 7-1106, 7-1202, 7-1262, 7-1280, 7-1303, 7-1338, 7-1358, 7-1574, 7-1576, 7-1594, 7-1605, 7-1652, 7-1730, 7-1732, 7-1733, 7-1750, 7-1764, 7-1808, 7-1809, 7-1810, and 7-1811 each showed a pesticidal rate of 70% or more at a concentration of 1 ppm.


Furthermore, the compounds of Compound Nos. 6-271, 6-367, 6-389, 6-426, 6-523, 6-1104, 6-1577, 6-1695, 6-1851, 6-2110, 7-424, 7-444, 7-523, 7-1104, 7-1124, 7-1260, 7-1263, 7-1577, 7-1616, 7-1731, 7-1773, and 7-1851 each showed a pesticidal rate of 70% or more at a concentration of 10 ppm.


Meanwhile, the compound (A) had a pesticidal rate of 50% or less at a concentration of 10 ppm.


Test Example 4

Pesticidal Test Against Choristoneura magnanima


A thinly sliced artificial feed was immersed for 30 seconds in a chemical solution in which a test compound had been prepared at a predetermined concentration, and air-dried, and then put into a 7 cm polyethylene cup having a filter paper laid on the bottom thereof; and 2-stage larvae of Choristoneura magnanima were released. They were left to stand in a thermostatic chamber at 25° C., and the numbers of the living pests and the dead pests were examined after 6 days. The test was carried out with five larvae per group in two replicates.


Further, the above compound (A) was used as a comparative compound.


As the results of the above tests, the compounds of Compound Nos. 6-72, 6-80, 6-90, 6-271, 6-349, 6-366, 6-367, 6-426, 6-427, 6-1104, 6-1106, 6-1182, 6-1260, 6-1263, 6-1358, 6-1574, 6-1577, 6-1595, 6-1596, 6-1652, 6-1654, 6-1655, 6-1672, 6-1673, 6-1674, 6-1695, 6-1730, 6-1732, 6-1733, 6-1750, 6-1751, 6-1809, 6-1811, 6-1828, 6-1829, 6-1830, 6-1851, 7-90, 7-348, 7-366, 7-382, 7-389, 7-444, 7-502, 7-504, 7-505, 7-523, 7-1104, 7-1106, 7-1107, 7-1124, 7-1125, 7-1260, 7-1262, 7-1263, 7-1280, 7-1281, 7-1303, 7-1358, 7-1359, 7-1574, 7-1576, 7-1577, 7-1594, 7-1595, 7-1605, 7-1616, 7-1617, 7-1652, 7-1730, 7-1732, 7-1733, 7-1750, 7-1764, 7-1773, 7-1808, 7-1809, 7-1810, 7-1811, 7-1829, and 7-1851 each showed a pesticidal rate of 70% or more at a concentration of 1 ppm.


Furthermore, the compounds of Compound Nos. 6-382, 6-446, 6-460, 6-2110, 7-424, 7-538, and 7-1606 each showed a pesticidal rate of 70% or more at a concentration of 10 ppm.


Meanwhile, the compound (A) had a pesticidal rate of 50% or less at a concentration of 10 ppm.


Test Example 5

Pesticidal Test Against Helicoverpa armigera


A cabbage leaf disk was immersed for 30 seconds in a chemical solution in which a test compound had been prepared at a predetermined concentration, and air-dried. The leaf disk was put into a 6-hole plastic cup having a filter paper laid on the bottom thereof, and 2-stage larvae of Helicoverpa armigera were released with one insect being released per hole. They were left to stand in a thermostatic chamber at 25° C., and the numbers of the living pests and the dead pests were examined after 3 days. The test was carried out with five larvae per group in two replicates.


Further, the above compound (A) was used as a comparative compound.


As the results of the above tests, the compounds of Compound Nos. 6-72, 6-80, 6-90, 6-271, 6-347, 6-348, 6-349, 6-366, 6-367, 6-382, 6-389, 6-426, 6-427, 6-446, 6-449, 6-460, 6-503, 6-504, 6-505, 6-522, 6-523, 6-524, 6-538, 6-1104, 6-1106, 6-1260, 6-1262, 6-1263, 6-1281, 6-1341, 6-1358, 6-1359, 6-1574, 6-1576, 6-1577, 6-1594, 6-1595, 6-1596, 6-1652, 6-1654, 6-1655, 6-1672, 6-1673, 6-1674, 6-1695, 6-1730, 6-1732, 6-1733, 6-1750, 6-1751, 6-1808, 6-1809, 6-1811, 6-1828, 6-1829, 6-1830, 6-1851, 6-2110, 7-90, 7-348, 7-366, 7-382, 7-389, 7-424, 7-444, 7-502, 7-505, 7-522, 7-523, 7-538, 7-1106, 7-1107, 7-1125, 7-1262, 7-1263, 7-1280, 7-1303, 7-1338, 7-1358, 7-1359, 7-1574, 7-1576, 7-1577, 7-1594, 7-1595, 7-1605, 7-1606, 7-1616, 7-1617, 7-1652, 7-1730, 7-1731, 7-1732, 7-1733, 7-1750, 7-1751, 7-1764, 7-1773, 7-1808, 7-1809, 7-1810, 7-1811, 7-1829, and 7-1851 each showed a pesticidal rate of 70% or more at a concentration of 1 ppm.


Furthermore, the compound of Compound No. 7-1104 showed a pesticidal rate of 70% or more at a concentration of 10 ppm.


Meanwhile, the compound (A) had a pesticidal rate of 50% or less at a concentration of 10 ppm.


Test Example 6

Pesticidal Test Against Laodelphax striatellus


2.5 ml of an acetone solution in which a test compound had been prepared at a predetermined concentration was sprayed on rice seedlings, air-dried, and then put into a glass tube having a diameter of 3 cm and a height of 13 cm, having water therein, and 3-stage larvae of Laodelphax striatellus were released and the tube was capped. They were left to stand in a thermostatic chamber at 25° C., and the numbers of the living pests and the dead pests were examined after 6 days. The test was carried out with ten larvae per group in two replicates.


As the results of the above tests, the compounds of Compound Nos. 1-491, 1-627, 2-491, 6-39, 6-45, 6-47, 6-57, 6-71, 6-72, 6-79, 6-80, 6-90, 6-147, 6-268, 6-269, 6-270, 6-271, 6-290, 6-304, 6-306, 6-311, 6-346, 6-347, 6-368, 6-382, 6-425, 6-427, 6-444, 6-445, 6-446, 6-460, 6-461, 6-503, 6-1104, 6-1106, 6-1107, 6-1124, 6-1126, 6-1140, 6-1147, 6-1182, 6-1183, 6-1184, 6-1185, 6-1202, 6-1203, 6-1204, 6-1218, 6-1225, 6-1260, 6-1261, 6-1262, 6-1263, 6-1280, 6-1281, 6-1282, 6-1296, 6-1303, 6-1338, 6-1339, 6-1340, 6-1341, 6-1358, 6-1359, 6-1360, 6-1374, 6-1381, 6-1574, 6-1575, 6-1576, 6-1577, 6-1594, 6-1595, 6-1596, 6-1610, 6-1617, 6-1652, 6-1653, 6-1654, 6-1655, 6-1672, 6-1673, 6-1674, 6-1688, 6-1695, 6-1730, 6-1731, 6-1732, 6-1733, 6-1734, 6-1750, 6-1751, 6-1752, 6-1754, 6-1766, 6-1773, 6-1808, 6-1809, 6-1810, 6-1811, 6-1828, 6-1829, 6-1830, 6-1851, 6-2110, 6-3348, 6-3384, 6-5903, 6-5904, 6-5905, 6-5906, 6-5907, 6-5908, 6-5909, 6-5910, 6-5911, 6-5914, 7-47, 7-57, 7-90, 7-268, 7-285, 7-286, 7-288, 7-289, 7-301, 7-303, 7-304, 7-305, 7-311, 7-316, 7-346, 7-348, 7-368, 7-382, 7-389, 7-424, 7-426, 7-427, 7-444, 7-445, 7-446, 7-460, 7-467, 7-538, 7-825, 7-840, 7-948, 7-984, 7-1104, 7-1105, 7-1106, 7-1107, 7-1124, 7-1125, 7-1126, 7-1140, 7-1147, 7-1182, 7-1183, 7-1184, 7-1185, 7-1202, 7-1203, 7-1204, 7-1218, 7-1225, 7-1260, 7-1261, 7-1262, 7-1263, 7-1280, 7-1281, 7-1282, 7-1296, 7-1303, 7-1338, 7-1339, 7-1340, 7-1341, 7-1358, 7-1359, 7-1360, 7-1374, 7-1381, 7-1417, 7-1574, 7-1575, 7-1576, 7-1577, 7-1594, 7-1595, 7-1596, 7-1605, 7-1606, 7-1608, 7-1610, 7-1616, 7-1617, 7-1638, 7-1639, 7-1645, 7-1652, 7-1672, 7-1673, 7-1730, 7-1731, 7-1732, 7-1733, 7-1750, 7-1751, 7-1752, 7-1764, 7-1766, 7-1773, 7-1794, 7-1808, 7-1809, 7-1810, 7-1811, 7-1828, 7-1829, 7-1844, 7-1851, 7-3348, 7-3369, 7-5902, 7-5903, 7-5904, 7-5906, 7-5907, 7-5909, 7-5912, 8-289, 8-304, 8-840, 9-270, 9-290, 9-291, 9-306, 9-2164, 9-2322, 12-835, and 12-864 each showed a pesticidal rate of 70% or more at a concentration of 100 ppm.


Test Example 7

Pesticidal Test Against Musca domestica


1 ml of an acetone solution in which a test compound had been prepared at a predetermined concentration was added dropwise to a petri dish having a diameter of 9 cm, and air-dried, and then the female adults of Musca domestica were released and the petri dish was capped. They were left to stand in a thermostatic chamber at 25° C., and the numbers of the living pests and the dead pests were examined after 1 day. The test was carried out with five larvae per group in two replicates.


As the results of the above tests, the compounds of Compound Nos. 1-1925, 1-1968, 6-39, 6-47, 6-72, 6-272, 6-293, 6-346, 6-347, 6-348, 6-366, 6-368, 6-382, 6-389, 6-426, 6-427, 6-428, 6-450, 6-452, 6-453, 6-460, 6-503, 6-504, 6-505, 6-522, 6-523, 6-524, 6-538, 6-1105, 6-1107, 6-1124, 6-1125, 6-1126, 6-1147, 6-1184, 6-1204, 6-1218, 6-1260, 6-1281, 6-1338, 6-1341, 6-1358, 6-1359, 6-1360, 6-1374, 6-1575, 6-1576, 6-1577, 6-1594, 6-1596, 6-1617, 6-1652, 6-1672, 6-1673, 6-1695, 6-1730, 6-1731, 6-1732, 6-1733, 6-1734, 6-1750, 6-1751, 6-1752, 6-1773, 6-1808, 6-1809, 6-1810, 6-1811, 6-1828, 6-1829, 6-1830, 6-1851, 6-2110, 6-5905, 7-39, 7-57, 7-90, 7-268, 7-346, 7-348, 7-349, 7-366, 7-367, 7-368, 7-382, 7-389, 7-424, 7-428, 7-444, 7-446, 7-449, 7-504, 7-522, 7-538, 7-1104, 7-1105, 7-1106, 7-1107, 7-1126, 7-1262, 7-1280, 7-1282, 7-1296, 7-1303, 7-1338, 7-1340, 7-1358, 7-1359, 7-1360, 7-1381, 7-1417, 7-1574, 7-1575, 7-1576, 7-1577, 7-1596, 7-1652, 7-1731, 7-1732, 7-1733, 7-1750, 7-1752, 7-1764, 7-1766, 7-1730, 7-1773, 7-1794, 7-1808, 7-1809, 7-1810, 7-1811, 7-1828, 7-1829, 7-1851, 9-2164, 9-2322, 11-777, 11-835, 12-777, 12-835, 12-864, 17-1103, and 27-627 each showed a pesticidal rate of 70% or more at a concentration of 100 ppm.


Test Example 8

Pesticidal Test Against Blattella germanica


1 ml of an acetone solution in which a test compound had been prepared at a predetermined concentration was added dropwise to a petri dish having a diameter of 9 cm, and air-dried, and then the female adults of Blattella germanica were released and the petri dish was capped. They were left to stand in a thermostatic chamber at 25° C., and the numbers of the living pests and the dead pests were examined after 1 day. The test was carried out with five larvae per group in two replicates.


As the results of the above tests, the compounds of Compound Nos. 1-1925, 6-39, 6-47, 6-346, 6-347, 6-367, 6-368, 6-382, 6-389, 6-426, 6-427, 6-503, 6-538, 6-1105, 6-1106, 6-1107, 6-1124, 6-1125, 6-1126, 6-1147, 6-1184, 6-1204, 6-1218, 6-1280, 6-1296, 6-1338, 6-1358, 6-1359, 6-1575, 6-1576, 6-1577, 6-1594, 6-1595, 6-1596, 6-1610, 6-1617, 6-1730, 6-1731, 6-1732, 6-1733, 6-1750, 6-1751, 6-1752, 6-1773, 6-1811, 6-5905, 7-57, 7-268, 7-305, 7-347, 7-349, 7-367, 7-382, 7-389, 7-424, 7-444, 7-446, 7-502, 7-505, 7-538, 7-1104, 7-1105, 7-1106, 7-1107, 7-1125, 7-1126, 7-1261, 7-1262, 7-1280, 7-1282, 7-1296, 7-1303, 7-1381, 7-1574, 7-1575, 7-1576, 7-1577, 7-1594, 7-1595, 7-1596, 7-1617, 7-1731, 7-1732, 7-1733, 7-1750, 7-1752, 7-1766, 7-1773, and 7-1851 each showed a pesticidal rate of 70% or more at a concentration of 100 ppm.


Test Example 9

Pesticidal Test Against Culex pipiens Molestus


1 ml of an acetone solution in which a test compound had been prepared at a predetermined concentration was added dropwise to a petri dish having a diameter of 9 cm, and air-dried, and then the female adults of Culex pipiens molestus were released and the petri dish was capped. They were left to stand in a thermostatic chamber at 25° C., and the numbers of the living pests and the dead pests were examined after 1 day of treatment. The test was carried out with five larvae per group in two replicates.


As the results of the above tests, the compounds of Compound Nos. Compound No. 7-424, 7-1574, 7-1577, 7-1730, 7-1732, and 7-1733 each showed a pesticidal rate of 70% or more at a concentration of 1000 ppm.


Test Example 10

Pesticidal Test Against Coptotermes formosanus


20 μl of an acetone solution in which a test compound had been prepared at a predetermined concentration was added dropwise to the filter paper having a diameter of 2.6 mm included in a polypropylene cup, and air-dried, and then 20 dl of water was added thereto. Coptotermes formosanus was released and the cup was capped. They were left to stand in a thermostatic chamber at 28° C., and the numbers of the living pests and the dead pests were examined after 5 days of treatment. The test was carried out with ten larvae per group in two replicates.


As the results of the above tests, the compounds of Compound Nos. Compound No. 6-460, 6-1260, 6-1652, 7-268, 7-424, 7-1104, 7-1574, 7-1577, 7-1730, 7-1732, and 7-1733 each showed a pesticidal rate of 70% or more at a concentration of 30 ppm.


According to the present invention, it becomes possible to provide a novel amide derivative. The amide derivative shows a significant effect for a pest control activity, and has a high industrial availability.


The present invention also provides a composition and method for exterminating animal parasites.


WO2005/21488, WO2005/73165, WO2006/137376, and WO2006/137395 disclose various compounds which are amide derivatives having the ability to control pests, and methods for using them. Further WO2009/080203 discloses amide derivatives which are animal parasiticides, and methods for using them. In addition, conventional parasiticides for administration to an animal to exterminate animal parasites include formulations of imidacloprid, fipronil, etc.


However, some parasites are impossible or difficult to exterminate with said animal parasiticides.


Thus, an objective of the invention is to provide a composition that has excellent activity for exterminating animal parasites, and a method for exterminating animal parasites.


As the result of earnest research for solving the above problem, the present inventors found that an aromatic carboxamide derivative represented by Formula (A1) of the present invention is a novel compound that is not disclosed in the literature, and a composition containing the present aromatic carboxamide derivative as an active ingredient has excellent activity for exterminating animal parasites, thereby completing the present invention.


A first aspect of the present invention provides a composition for exterminating animal parasites which comprises as an active ingredient at least one amide derivative represented by the following Formula (A1).




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In Formula (A1), Q1 represents a phenyl group or a phenyl group substituted with a halogen atom; X1 represents a fluorine atom, and X2, X3, and X4 are each a hydrogen atom; R1 represents a hydrogen atom or a C1-C3 alkyl group; R2 is a hydrogen atom; Y1 and Y5 each independently represent a halogen atom or a C1-C3 haloalkyl group; Y2 and Y4 each represent a hydrogen atom; and Y3 represents a heptafluoroisopropyl group.


In Formula (A1), Q1 represents a phenyl group or a phenyl group substituted with a single fluorine atom; R1 represents a hydrogen atom or a methyl group; and Y1 and Y5 each independently represent a bromine or iodine atom or a trifluoromethyl group preferably.


The amide derivative represented by Formula (A1) is preferably 2-fluoro-3-(N-methylbenzamide)-N-(2-bromo-6-trifluoromethyl-4-(heptafluoropropan-2-yl)phenyl)benzamide, 2-fluoro-3-(4-fluoro-N-methylbenzamide)-N-(2-iodo-6-trifluoromethyl-4-(heptafluoropropan-2-yl)phenyl)benzamide, 2-fluoro-3-(3-fluoro-N-methylbenzamide)-N-(2-iodo-6-trifluoromethyl-4-(heptafluoropropan-2-yl)phenyl)benzamide, 2-fluoro-3-(4-fluorobenzamide)-N-(2-iodo-6-trifluoromethyl-4-(heptafluoropropan-2-yl)phenyl)benzamide, or 2-fluoro-3-(N-methylbenzamide)-N-(2,6-dibromo-4-(heptafluoropropan-2-yl)phenyl)benzamide.


In Formula (A1), Q1 represents preferably a phenyl group, a 2-fluorophenyl group, a 3-fluorophenyl group, a 4-fluorophenyl group, a 2-chlorophenyl group, a 3-chlorophenyl group, a 4-chlorophenyl group, a 2-bromophenyl group, a 3-bromophenyl group, a 4-bromophenyl group, a 2-iodophenyl group, a 3-iodophenyl group, or a 4-iodophenyl group.


The amide derivative represented by Formula (A1) is preferably 3-benzamide-N-(2-bromo-chloro-4-(heptafluoropropan-2-yl)phenyl)-2-fluorobenzamide, 3-benzamide-N-(2,6-d iodo-4-(heptafluoropropan-2-yl)phenyl)-2-fluorobenzamide, 3-benzamide-N-(2,6-dibromo-4-(heptafluoropropan-2-yl)phenyl)-2-fluorobenzamide, N-(2,6-dibromo-4-(heptafluoropropan-2-yl)phenyl)-2-fluoro-3-(N-methylbenzamide)benzamide, N-(2,6-dichloro-4-(heptafluoropropan-2-yl)phenyl)-2-fluoro-3-(N-methylbenzamide)benzamide, N-(2,6-diiodo-4-(heptafluoropropan-2-yl)phenyl)-2-fluoro-3-(N-methylbenzamide)benzamide, N-(2,6-diiodo-4-(heptafluoropropan-2-yl)phenyl)-2-fluoro-3-(2-fluorobenzamide)benzamide, N-(2,6-diiodo-4-(heptafluoropropan-2-yl)phenyl)-2-fluoro-3-(4-fluorobenzamide)benzamide, 3-(2,6-difluorobenzamide)-N-(2,6-diiodo-4-(heptafluoropropan-2-yl)phenyl)-2-fluorobenzamide, N-(2-bromo-6-iodo-4-(heptafluoropropan-2-yl)phenyl)-2-fluoro-3-(N-methylbenzamide)benzamide,


N-(2,6-diiodo-4-(heptafluoropropan-2-yl)phenyl)-2-fluoro-3-(3-fluorobenzamide)benzamide, N-(3-(2,6-diiodo-4-(heptafluoropropan-2-yl)phenylcarbamoyl)-2-fluorophenyl)-2-fluoro-N-methylbenzamide, N-(2,6-diiodo-4-(heptafluoropropan-2-yl)phenyl)-2-fluoro-3-(3-fluoro-N-methylbenzamide)benzamide, N-(2,6-diiodo-4-(heptafluoropropan-2-yl)phenyl)-2-fluoro-3-(4-fluoro-N-methylbenzamide)benzamide, N-(3-(2,6-diiodo-4-(heptafluoropropan-2-yl)phenylcarbamoyl)-2-fluorophenyl)-2,6-difluoro-N-methylbenzamide, N-(2,6-dibromo-4-(heptafluoropropan-2-yl)phenyl)-2-fluoro-3-(2-fluorobenzamide)benzamide, N-(2,6-dibromo-4-(heptafluoropropan-2-yl)phenyl)-2-fluoro-3-(3-fluorobenzamide)benzamide, N-(2,6-dibromo-4-(heptafluoropropan-2-yl)phenyl)-2-fluoro-3-(4-fluorobenzamide)benzamide, N-(2,6-dibromo-4-(heptafluoropropan-2-yl)phenyl)-3-(2,6-difluorobenzamide)-2-fluorobenzamide, N-(3-(2,6-dibromo-4-(heptafluoropropan-2-yl)phenylcarbamoyl)-2-fluorophenyl)-2-fluoro-N-methylbenzamide, N-(2,6-dibromo-4-(heptafluoropropan-2-yl)phenyl)-2-fluoro-3-(3-fluoro-N-methylbenzamide)benzamide, N-(2,6-dibromo-4-(heptafluoropropan-2-yl)phenyl)-2-fluoro-3-(4-fluoro-N-methylbenzamide)benzamide, N-(3-(2,6-dibromo-4-(heptafluoropropan-2-yl)phenylcarbamoyl)-2-fluorophenyl)-2,6-difluoro-N-methylbenzamide,


3-benzamide-N-(2-bromo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-2-fluorobenzamide, N-(2-bromo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-2-fluoro-3-(N-methylbenzamide)benzamide, 3-benzamide-2-fluoro-N-(4-(heptafluoropropan-2-yl)-2,6-bis(trifluoromethyl)phenyl)benzamide, 3-benzamide-2-fluoro-N-(2-iodo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)phenyl)benzamide, 3-benzamide-N-(2-bromo-6-(pentafluoroethyl)-4-(heptafluoropropan-2-yl)phenyl)-2-fluorobenzamide, 2-fluoro-N-(2-iodo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-3-(N-methylbenzamide)benzamide, 2-fluoro-N-(2-fluoro-3-(2-iodo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-N-methylbenzamide, 2-fluoro-3-(3-fluoro-N-methylbenzamide)-N-(2-iodo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)phenyl)benzamide, 2-fluoro-3-(4-fluoro-N-methylbenzamide)-N-(2-iodo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)phenyl)benzamide, 2,6-difluoro-N-(2-fluoro-3-(2-iodo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)phenyl)-N-methylbenzamide, 2-fluoro-3-(2-fluorobenzamide)-N-(2-iodo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)phenyl)benzamide, 2-fluoro-3-(3-fluorobenzamide)-N-(2-iodo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)phenyl)benzamide, N-(3-(2-bromo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)-2-fluorophenyl)-2-fluoro-N-methylbenzamide, N-(3-(2-bromo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)phenylcarbamoyl)-2-fluorophenyl)-2,6-difluoro-N-methylbenzamide, N-(2-bromo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-2-fluoro-3-(3-fluoro-N-methylbenzamide)benzamide, N-(2-bromo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-2-fluoro-3-(4-fluoro-N-methylbenzamide)benzamide, N-(2-bromo-4-(heptafluoropropan-2-yl)-6-(trifluoromethy)phenyl)-2-fluoro-3-(2-fluowobenzamide)benzamide, N-(2-bromo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-2-fluoro-3-(3-fluorobenzamide)benzamide, N-(2-bromo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-2-fluoro-3-(4-fluorobenzamide)benzamide,


2-fluoro-3-(4-fluorobenzamide)-N-(2-iodo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)phenyl)benzamide, 3-(2,6-difluorobenzamide)-2-fluoro-N-(2-iodo-4-(heptafluoropropan-2-yl)-6-(trifluoromethy)phenyl)benzamide, N-(2-bromo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-3-(2,6-difluorobenzamide)-2-fluorobenzamide, 3-(2,4-dichlorobenzamide)-2-fluoro-N-(2-iodo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)phenyl)benzamide, 3-(2-chloro-4-fluorobenzamide)-2-fluoro-N-(2-iodo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)phenyl)benzamide, 3-(2-chlorobenzamide)-2-fluoro-N-(2-iodo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)phenyl)benzamide, or N-(2-chloro-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-2-fluoro-3-(N-methylbenzamide)benzamide.


A second aspect of the present invention provides a method for exterminating animal parasites comprising administering to the animal the composition for exterminating animal parasites


Wherein, the animal parasite is preferably an ectoparasite and the ectoparasite is more preferably Siphonaptera pests or the ectoparasite is Acarina pests.


According to the present invention, a composition which has excellent activity for exterminating animal parasites and a method for exterminating animal parasites are provided.


A composition for exterminating animal parasites according to the present invention includes at least one amide derivative represented by the following Formula (A1).


By adopting such a constitution, it becomes possible to show excellent activity for exterminating animal parasites in the case of giving the composition to an animal.




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In Formula (A1), Q1 represents a phenyl group or a phenyl group substituted with a halogen atom. X, represents a fluorine atom, and X2, X3, and X4 are each a hydrogen atom. R1 represents a hydrogen atom or a C1-C3 alkyl group, and R2 is a hydrogen atom. Y1 and Y5 each independently represent a halogen atom or a C1-C3 haloalkyl group, Y2 and Y4 each represent a hydrogen atom, and Y3 represents a heptafluoroisopropyl group.


The terms used in the formulae including the Formula (A1) and the like according to the present invention, have the same meanings as described below in the definitions.


The “halogen atom” represents a fluorine atom, a chlorine atom, a bromine atom, or an iodine atom.


The expression “Ca-Cb (wherein a and b represent an integer of 1 or more)”, for example, “C1-C3” means the number of carbon atoms of from 1 to 3, the “C2-C6” means the number of carbon atoms of from 2 to 6.


The “C1-C3 alkyl group” in the present invention represents, for example, a linear or branched alkyl group having from 1 to 3 carbon atoms such as methyl, ethyl, n-propyl, i-propyl, and the like.


The “C1-C3 haloalkyl group” represents, for example, a linear or branched alkyl group having from 1 to 3 carbon atoms, that is substituted with one or more halogen atoms which may be the same as or different from each other, such as trifluoromethyl, pentafluoroethyl, heptafluoro-n-propyl, heptafluoro-i-propyl, 2,2-difluoroethyl, 2,2-dichloroethyl, 2,2,2-trifluoroethyl, 2-fluoroethyl, 2-chloroethyl, 2-bromoethyl, 2-iodoethyl, 2,2,2-trichloroethyl, 2,2,2-tribromoethyl, 1,3-difluoro-2-propyl, 1,3-dichloro-2-propyl, 1-chloro-3-fluoro-2-propyl, 1,1,1-trifluoro-2-propyl, 2,3,3,3-trifluoro-n-propyl, 1,1,1,3,3,3-hexafluoro-2-propyl, 1,1,1,3,3,3-hexafluoro-2-chloro-2-propyl, 1,1,1,3,3,3-hexafluoro-2-bromo-2-propyl, 1,1,2,3,3,3-hexafluoro-2-chloro-n-propyl, 1,1,2,3,3,3-hexafluoro-2-bromo-n-propyl, 1,1,2,3,3,3-hexafluoro-1-bromo-2-propyl, 2,2,3,3,3-pentafluoro-n-propyl, 3-fluoro-n-propyl, 3-chloro-n-propyl, 3-bromo-n-propyl, and the like.


The “C1-C6 alkyl group” in the present invention represents, for example, a linear or branched alkyl group having from 1 to 6 carbon atoms such as methyl, ethyl, n-propyl, i-propyl, n-butyl, s-butyl, t-butyl, n-pentyl, 2-pentyl, neopentyl, 4-methyl-2-pentyl, n-hexyl, 3-methyl-n-pentyl, and the like.


The “C3-C9 cycloalkyl group” represents, for example, a cycloalkyl group having from 3 to 9 carbon atoms, that has a cyclic structure, such as cyclopropyl, cyclobutyl, cyclopentyl, 2-methylcyclopentyl, 3-methylcyclopentyl, cyclohexyl, 2-methylcyclohexyl, 3-methylcyclohexyl, 4-methylcyclohexyl, and the like.


The “C2-C6 alkenyl group” represents, for example, an alkenyl group having from 2 to 6 carbon atoms, that has a double bond in the carbon chain, such as vinyl, allyl, 2-butenyl, 3-butenyl, and the like.


The “C2-C6 alkynyl group” represents, for example, an alkynyl group having from 2 to 6 carbon atoms, that has a triple bond in the carbon chain, such as propargyl, 1-butyn-3-yl, l-butyn-3-methyl-3-yl, and the like.


The compounds represented by Formula (A1) according to the present invention may include one or plural chiral carbon atoms or chiral centers in their structural Formulae, and thus two or more optical isomers may exist. However, the present invention includes each of the optical isomers and a mixture thereof at any proportions. Further, the compounds represented by Formula (A1) according to the present invention may include two or more kinds of geometrical isomers derived from carbon-carbon double bonds in the structural Formulae. The present invention includes each of the geometrical isomers and a mixture thereof at any proportions.


The representative methods for producing the compound according to the present invention are shown below, and the method for producing the amide derivative according to the present invention is not limited to the preparation methods below.


In Formula shown in the following preparation method, X1, X2, X3, X4, R1, R2, Q1, Y1, Y2, Y3, Y4, and Y5 represent the same definitions as X1, X2, X3, X4, R1, R2, Q1, Y1, Y2, Y3, Y4, and Y5, respectively, in Formula (A1). LG represents a functional group having a leaving ability, such as a halogen atom, a hydroxy group, or the like, Hal represents a chlorine atom or a bromine atom, and Xa and Xb represent chlorine atoms, bromine atoms, or iodine atoms. R3 represents a C1-C6 alkyl group, a C3-C9 cycloalkyl group, a C2-C6 alkenyl group, a C2-C6 alkynyl group.


Preparation Method 1



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1-(i): Formula (A11)+Formula (A12)→Formula (A13))


A nitro aromatic carboxamide derivative represented by Formula (A13) can be prepared by reacting a nitro aromatic carboxylic acid derivative having a leaving group represented by Formula (A11) with an aromatic amine derivative represented by Formula (A 12) in a suitable solvent or without a solvent. In the present step, a suitable base can be used.


The solvent may be any of those which do not inhibit the present reaction significantly. Examples thereof may include water and aromatic hydrocarbons such as benzene, toluene, xylene, and the like, halogenated hydrocarbons such as dichloromethane, chloroform, carbon tetrachloride, and the like, chained or cyclic ethers such as diethyl ether, dioxane, tetrahydrofuran, 1,2-dimethoxy ethane, and the like, esters such as ethyl acetate, butyl acetate, and the like, alcohols such as methanol, ethanol, and the like, ketones such as acetone, methyl isobutyl ketone, cyclohexanone, and the like, amides such as dimethyl formamide, dimethylacetamide, and the like, nitriles such as acetonitrile and the like, and inert solvents such as 1,3-dimethyl-2-imidazolidinone and the like. These solvents may be used alone or as a mixture of two or more kinds thereof.


Furthermore, examples of the base may include organic bases such as triethylamine, tri-n-butyl amine, pyridine, 4-dimethylamino pyridine, and the like, alkali metal hydroxides such as sodium hydroxide, potassium hydroxide, and the like, carbonates such as sodium hydrogen carbonate, potassium carbonate, and the like, phosphates such as dipotassium monohydrogen phosphate, trisodium phosphate, and the like, alkali metal hydride salts such as sodium hydride and the like, alkali metal alkoxides such as sodium methoxide, sodium ethoxide, and the like, and lithium amides such as lithium diisopropyl amide, and the like.


These bases may be appropriately used in an amount in the range from 0.01-fold molar equivalent to 5-fold molar equivalents with respect to the compound represented by Formula (A11).


The reaction temperature may be appropriately selected from −20° C. to the reflux temperature of the solvent used. Further, the reaction time may be appropriately selected within the range from several minutes to 96 hours.


Among the compounds represented by Formula (A11), the aromatic carbonyl halide derivative can be prepared easily by a general method using a halogenating agent from an aromatic carboxylic acid. Examples of the halogenating agent include thionyl chloride, thionyl bromide, phosphorus oxychloride, oxalyl chloride, phosphorus trichloride, and the like.


Meanwhile, it is possible to prepare the compound represented by Formula (A13) from the nitro aromatic carboxylic acid derivative and the compound represented by Formula (A12) without using a halogenating agent. Examples of the method may include a method described in, for example, Chem. Ber. p. 788 (1970), in which a condensing agent such as N,N′-dicyclohexylcarbodiimide and the like is appropriately used, suitably with the use of an additive such as 1-hydroxybenzotriazole and the like. Other condensing agents that can be used in this case may include 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide, 1,1′-carbonylbis-1H-imidazole, and the like.


Furthermore, examples of other methods for producing the compound represented by Formula (A13) may include a mixed acid anhydride method using chloroformic acid esters, and examples thereof include a method described in J. Am. Chem. Soc., p. 5012 (1967), whereby the compound represented by Formula (A13) can be prepared. Examples of the chloroformic acid esters used in this case may include isobutyl chloroformate, isopropyl chloroformate and the like. In addition to chloroformic acid esters, diethylacetyl chloride, trimethylacetyl chloride and the like may also be included.


Both the method using a condensing agent and the mixed acid anhydride method are not limited by the solvent, the reaction temperature, and the reaction time according to the literature above. An inert solvent may be used which does not inhibit the progress of the appropriate reaction significantly, and the reaction temperature and the reaction time may also be selected appropriately according to the progress of the reaction.


1-(ii): Formula (A13)→Formula (A14)


An aromatic carboxamide derivative having an amino group represented by Formula (A14) can be derived from the aromatic carboxamide derivative having a nitro group represented by Formula (A13) by means of a reduction reaction. Examples of such reduction include a method using a hydrogenation reaction and a method using a metal compound (for example, stannous chloride (anhydride), iron powder, zinc powder, and the like).


The reaction of the former method can be carried out in a suitable solvent in the presence of a catalyst at normal pressure or a higher pressure under a hydrogen atmosphere. Examples of the catalyst may include palladium catalysts such as palladium-carbon and the like, nickel catalysts such as Raney-nickel and the like, cobalt catalysts, ruthenium catalysts, rhodium catalysts, platinum catalysts, and the like, and examples of the solvent may include water; alcohols such as methanol, ethanol, and the like; aromatic hydrocarbons such as benzene, toluene, and the like; chained or cyclic ethers such as ether, dioxane, tetrahydrofuran, and the like; and esters such as ethyl acetate and the like. The pressure may be appropriately selected within a range of 0.1 MPa to 10 MPa, the reaction temperature may be appropriately selected within a range of −20° C. to the reflux temperature of the solvent used, and the reaction time may be appropriately selected within a range of several minutes to 96 hours, whereby the compound of Formula (14) can be efficiently prepared.


Examples of the latter method include a method using stannous chloride (anhydride) as a metal compound under the conditions described in “Organic Syntheses” Coll. Vol. III, P. 453.


1-(iii): Formula (A14)→Formula (A15)


(Method A)


A compound represented by Formula (A15) can be prepared by reacting the compound represented by Formula (A14) with an aldehyde or a ketone in a solvent, and reacting them under a hydrogen atmosphere with the addition of a catalyst.


The solvent may be any of those which do not inhibit the progress of the reaction significantly, and examples thereof may include aliphatic hydrocarbons such as hexane, cyclohexane, methylcyclohexane, and the like, aromatic hydrocarbons such as benzene, xylene, toluene, and the like, halogenated hydrocarbons such as dichloromethane, chloroform, carbon tetrachloride, 1,2-dichloroethane, and the like, ethers such as diethyl ether, dioxane, tetrahydrofuran, 1,2-dimethoxy ethane, and the like, amides such as dimethyl formamide, dimethylacetamide, and the like, nitriles such as acetonitrile, propionitrile, and the like, ketones such as acetone, methyl isobutyl ketone, cyclohexanone, methyl ethyl ketone, and the like, esters such as ethyl acetate, butyl acetate, and the like, alcohols such as methanol, ethanol, and the like, inert solvents such as 1,3-dimethyl-2-imidazolidinone, sulfolane, dimethylsulfoxide, and the like, water, and the like. These solvents may be used alone or as a mixture of two or more kinds thereof.


Examples of the catalyst may include palladium catalysts such as palladium-carbon, palladium hydroxide-carbon, and the like, nickel catalysts such as Raney-nickel and the like, cobalt catalysts, platinum catalysts, ruthenium catalysts, rhodium catalysts, and the like.


Examples of the aldehydes may include formaldehyde, acetaldehyde, propionaldehyde, trifluoroacetaldehyde, difluoroacetaldehyde, fluoroacetaldehyde, chloroacetaldehyde, dichloroacetaldehyde, trichloroacetaldehyde, bromoacetaldehyde, and the like.


Examples of the ketones may include acetone, perfluoroacetone, methyl ethyl ketone, and the like.


The reaction pressure may be appropriately selected within the range of 1 atm to 100 atm. The reaction temperature may be appropriately selected within the range from −20° C. to the reflux temperature of the solvent used. Further, the reaction time may be appropriately selected within the range from several minutes to 96 hours.


(Method B)


A compound represented by Formula (A 15) can be prepared by reacting the compound represented by Formula (A14) with an aldehyde or a ketone in a solvent, and treating the product with a reducing agent.


The solvent may be any of those which do not inhibit the progress of the reaction significantly, and examples thereof may include aliphatic hydrocarbons such as hexane, cyclohexane, methylcyclohexane, and the like, aromatic hydrocarbons such as benzene, xylene, toluene, and the like, halogenated hydrocarbons such as dichloromethane, chloroform, carbon tetrachloride, 1,2-dichloroethane, and the like, ethers such as diethyl ether, dioxane, tetrahydrofuran, 1,2-dimethoxy ethane, and the like, amides such as dimethyl formamide, dimethylacetamide, and the like, nitriles such as acetonitrile, propionitrile, and the like, ketones such as acetone, methyl isobutyl ketone, cyclohexanone, methyl ethyl ketone, and the like, esters such as ethyl acetate, butyl acetate, and the like, alcohols such as methanol, ethanol, and the like, inert solvents such as 1,3-dimethyl-2-imidazolidinone, sulfolane, dimethylsulfoxide, and the like, water, and the like. These solvents may be used alone or as a mixture of two or more kinds thereof.


Examples of the reducing agent may include, for example, borohydrides such as sodium borohydride, sodium cyanoborohydride, sodium triacetate borohydride, and the like.


Examples of the aldehydes may include formaldehyde, acetaldehyde, propionaldehyde, trifluoroacetaldehyde, difluoroacetaldehyde, fluoroacetaldehyde, chloroacetaldehyde, dichloroacetaldehyde, trichloroacetaldehyde, bromoacetaldehyde, and the like.


Examples of the ketones may include acetone, perfluoroacetone, methyl ethyl ketone, and the like.


The reaction temperature may be appropriately selected within the range from −20° C. to the reflux temperature of the solvent used. Further, the reaction time may be appropriately selected within the range from several minutes to 96 hours.


(Method C)


A compound of Formula (A15) can be prepared by reacting the compound represented by Formula (A14) with an aldehyde in a solvent or without a solvent.


The solvent may be any of those which do not inhibit the progress of the reaction significantly, and examples thereof may include aliphatic hydrocarbons such as hexane, cyclohexane, methylcyclohexane, and the like, aromatic hydrocarbons such as benzene, xylene, toluene, and the like, halogenated hydrocarbons such as dichloromethane, chloroform, carbon tetrachloride, 1,2-dichloroethane, and the like, ethers such as diethyl ether, dioxane, tetrahydrofuran, 1,2-dimethoxy ethane, and the like, amides such as dimethyl formamide, dimethylacetamide, and the like, nitriles such as acetonitrile, propionitrile, and the like, ketones such as acetone, methyl isobutyl ketone, cyclohexanone, methyl ethyl ketone, and the like, esters such as ethyl acetate, butyl acetate, and the like, alcohols such as methanol, ethanol, and the like, inert solvents such as 1,3-dimethyl-2-imidazolidinone, sulfolane, dimethylsulfoxide, and the like, inorganic acids such as sulfuric acid, hydrochloric acid, and the like, organic acids such as formic acid, acetic acid, and the like, water, and the like. These solvents may be used alone or as a mixture of two or more kinds thereof.


Examples of the aldehydes may include formaldehyde, acetaldehyde, propionaldehyde, and the like.


The reaction temperature may be appropriately selected within the range from −20° C. to the reflux temperature of the solvent used, and the reaction time may be appropriately selected within the range from several minutes to 96 hours.


1-(iv): Formula (A15)+Formula (A16)→Formula (A1)


An aromatic carboxamide derivative represented by Formula (A1) can be prepared by reacting the aromatic amine derivative represented by Formula (A 15) with the carboxylic acid derivative or the carbonate ester derivative having a leaving group represented by Formula (A16) in a suitable solvent. In the present step, a suitable base or solvent can be used, and as the base or solvent, those exemplified in 1-(i) can be used. Examples of the reaction temperature, the reaction time, and the like may include those exemplified in 1-(i).


In Formula (A16), the carbonyl chloride derivative can be prepared easily from a carboxylic acid derivative by a general method using a halogenating agent. The halogenating agent may include those exemplified in 1-(i).


There may be exemplified a method for producing a compound represented by Formula (A1) from the carboxylic acid derivative (A16) and the compound represented by Formula (A15) without the use of a halogenating agent, and the preparation can be conducted according to the method exemplified in 1-(i).


Preparation Method 2



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2-(i): Formula (A17)+Formula (A12)→Formula (A18)


A compound represented by Formula (A18) can be prepared by reacting the compound represented by Formula (A17) with a compound represented by Formula (A12) under the condition described in 1-(i).


2-(ii): Formula (A18)→Formula (A15)


A compound represented by Formula (A15) can be prepared by carrying out an amination reaction using an amination agent such as ammonia and the like according to the conditions described, for example, in J. Org. Chem. p. 280 (1958). However, the conditions such as a reaction solvent and the like are not restricted to those described in the literature, and an inert solvent which does not inhibit the proper progress of the reaction significantly may be used. The reaction temperature and reaction time may be suitably selected as the reaction proceeds. Further, examples of the amination agent include methylamine, ethylamine or the like, in addition to ammonia.


2-(iii): Formula (A15)+Formula (A16)→Formula (A1)


The compound represented by Formula (A1) can be prepared by reacting the compound represented by Formula (A15) with a compound represented by Formula (A16) according to the conditions described in l-(i).


Preparation Method 3



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3-(i): Formula (A19)+Formula (A12)→Formula (A20)


A compound represented by Formula (A20) can be prepared by reacting the compound represented by Formula (A19) and the compound represented by Formula (A12) according to the conditions described in 1-(i).


3-(ii): Formula (A20)→Formula (A21)


A compound represented by Formula (A21) can be prepared by reacting the nitro aromatic carboxamide derivative represented by Formula (A20) with a suitable fluorinating agent in a suitable solvent or without a solvent.


The solvent may be any of those which do not inhibit the progress of the reaction significantly, and examples thereof may include aliphatic hydrocarbons such as hexane, cyclohexane, methylcyclohexane, and the like, aromatic hydrocarbons such as benzene, toluene, xylene, and the like, halogenated hydrocarbons such as dichloromethane, chloroform, carbon tetrachloride, 1,2-dichloroethane, and the like, chained or cyclic ethers such as diethyl ether, dioxane, tetrahydrofuran, 1,2-dimethoxy ethane, and the like, esters such as ethyl acetate, butyl acetate, and the like, ketones such as acetone, methyl isobutyl ketone, cyclohexanone, methyl ethyl ketone, and the like, nitriles such as acetonitrile, propionitrile, and the like, and aprotic polar solvents such as 1,3-dimethyl-2-imidazolidinone, sulfolane, dimethylsulfoxide, N,N-dimethyl formamide, N-methyl pyrrolidone, N,N-dimethylacetamide, and the like. These solvents may be used alone or as a mixture of two or more kinds thereof.


Examples of the fluorinating agent may include 1,1,2,2-tetrafluoroethyl diethylamine, 2-chloro-1,1,2-trifluoroethyl diethylamine, trifluorodiphenylphospholane, difluorotriphenylphospholane, fluoroformic acid esters, sulfur tetrafluoride, potassium fluoride, potassium hydrogen fluoride, cesium fluoride, rubidium fluoride, sodium fluoride, lithium fluoride, antimony (III) fluoride, antimony (V) fluoride, zinc fluoride, cobalt fluoride, lead fluoride, copper fluoride, mercury (II) fluoride, silver fluoride, silver fluoroborate, thallium (I) fluoride, molybdenum (VI) fluoride, arsenic (III) fluoride, bromine fluoride, selenium tetrafluoride, tris(dimethylamino)sulfonium difluorotrimethylsilicate, sodium hexafluorosilicate, quaternary ammonium fluorides, (2-chloroethyl) diethylamine, diethylaminosulfur trifluoride, morpholinosulfur trifluoride, silicon tetrafluoride, hydrogen fluoride, hydrofluoric acid, hydrogen fluoride-pyridine complex, hydrogen fluoride-triethylamine complex, hydrogen fluoride salts, bis(2-methoxyethyl)amino sulfurtrifluoride, 2,2-difluoro-1,3-dimethyl-2-imidazolidinone, iodine pentafluoride, tris(diethylamino)phosphonium 2,2,3,3,4,4-hexafluorocyclobutanilide, triethylammonium hexafluorocylcobutanilide, hexafluoropropene, and the like. These fluorinating agents may be used alone or as a mixture of two or more kinds thereof.


The fluorinating agent may be appropriately selected and used as a solvent, in the range of 1-fold molar equivalent to 10-fold molar equivalents with respect to the nitro aromatic carboxamide derivative represented by Formula (A20).


Additives may be used, and examples thereof may include crown ethers such as 18-crown-6 and the like, phase transfer catalysts such as a tetraphenylphosphonium salt and the like, inorganic salts such as calcium fluoride, calcium chloride, and the like, metal oxides such as mercury oxide and the like, ion exchange resins, and the like. These additives may not only be added to the reaction system but also used as a pretreating agent for the fluorinating agent.


The reaction temperature may be appropriately selected within the range from −80° C. to the reflux temperature of the solvent used, and the reaction time may be appropriately selected within the range from several minutes to 96 hours.


Preparation Method 4



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4-(i): Formula (A22)+Formula (A16)→Formula (A23)


A carboxylic acid having an acylamino group represented by Formula (A23) can be prepared by reacting a compound represented by Formula (A22) as a starting material with a compound represented by Formula (A16) according to the conditions described in 1-(i).


4-(ii): Formula (A23)+Formula (A24)→Formula (A25)


The compound represented by Formula (A25) can be prepared by reacting the amide compound represented by Formula (A23) with the compound having a leaving group such as a halogen and the like, represented by Formula (A24) in a solvent or without a solvent. In the present step, a suitable base or solvent can be used, and as the base or solvent, those exemplified in 1-(i) can be used. Examples of the reaction temperature, the reaction time, and the like may include those exemplified in l-(i).


4-(iii): Formula (A25)→Formula (A26)


The compound represented by Formula (A26) can be prepared from the compound represented by Formula (A25) through hydrolysis conducted by a general technique or a method using a Pd catalyst. In the hydrolysis, the compound can be obtained by base hydrolysis using one equivalent to 5-fold molar amount of aqueous or alcoholic lithium hydroxide, sodium hydroxide, or potassium hydroxide in a single solvent of methanol, ethanol, tetrahydrofuran, or dioxane, or a combination thereof. Also in a non-aqueous solvent such as toluene and xylene, hydrolysis can be conducted with the combination of a base such as aqueous sodium hydroxide, potassium hydroxide, or lithium hydroxide and a phase-transfer catalyst such as tetrabutylammonium bromide, benzyltriethylammonium chloride, or crown ether. Alternatively, acid hydrolysis can be conducted with inorganic acid such as hydrochloric acid and sulfuric acid, organic acid such as acetic acid and trifluoroacetic acid, or strongly acidic resin.


The reaction temperature may be appropriately selected in the range from −20° C. to the reflux temperature of the solvent to be used. And the reaction time may be appropriately selected in the range from a few minutes to 96 hours.


The method using Pd can include, for example, the method described in Tetrahedron Letters p. 4371 (1987). The conditions such as the solvent and the reaction temperature are not limited to those described in the reference.


4-(iv): Formula (A26)→Formula (A27)


The compound represented by Formula (A27) can be prepared according to the known routine procedure in which the compound represented by Formula (A26) is reacted with thionyl chloride, oxalyl chloride, phosgene, phosphorus oxychloride, phosphorus pentachloride, phosphorous trichloride, thionyl bromide, phosphorus tribromide, diethylaminosulfur trifluoride, or the like.


4-(v): Formula (A27)+Formula (A12)→Formula (A1)


The compound represented by Formula (A1) can be produced by reacting the compound represented by Formula (A27) with the compound represented by Formula (A12) according to the conditions described in 1-(i).


4-(vi): Formula (A26)+Formula (A12)→Formula (A1)


The amide derivative represented by Formula (A1) can be produced by reacting the compound represented by Formula (A26) with the compound represented by Formula (A 12) according to the conditions of the method in which a condensing agent is used or the mixed anhydride method both described in 1-(i).


Production Method 5



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5-(i): Formula (A28)→Formula (A29)


The compound represented by Formula (A29) can be produced by fluorinating the compound represented by Formula (A28) according to the conditions described in 3-(ii).


5-(ii): Formula (A29)→Formula (A30)


The compound represented by Formula (A30) can be produced by reducing the compound represented by Formula (A29) according to the conditions described in 1-(ii).


In all of the preparation methods as described above, a desired product may be isolated from the reaction system after the reaction is completed according to a general method, but if required, purification can be carried out by operations such as recrystallization, column chromatography, distillation, and the like. In addition, the desired product can be also provided to the subsequent reaction process without being separated from the reaction system.


Hereinbelow, examples of the representative compounds of the amide derivative represented by Formula (A1) as an active ingredient for the composition for exterminating animal parasites according to the present invention will be given in Table A1 and Table A2 below, but the present invention is not limited thereto.


In addition, in the tables, “Me” represents a methyl group, “n-Pr” represents a normal propyl group, “CF3” represents a trifluoromethyl group, “C2F5” represents a pentafluoroethyl group, “n-C3F7” represents a heptafluoronormalpropyl group, “H” represents a hydrogen atom, “F” represents a fluorine atom, “Cl” represents a chlorine atom, “Br” represents a bromine atom, and “I” represents an iodine atom, respectively.




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TABLE A1





compound














number
Q1
R1
R2
X1
X2
X3
X4
Y1
Y2
Y3
Y4
Y5







6-940
phenyl
H
H
F
H
H
H
F
H
heptafluoroisopropyl
H
F


6-948
phenyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


6-952
2-chlorophenyl
H
H
F
H
H
H
F
H
heptafluoroisopropyl
H
Cl


6-956
3-bromophenyl
H
H
F
H
H
H
F
H
heptafluoroisopropyl
H
Br


6-970
2,6-difluorophenyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
I


6-1104
phenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
Br


6-1105
2-fluorophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
Br


6-1106
3-fluorophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
Br


6-1107
4-fluorophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
Br


6-1126
2,6-difluorophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
Br


6-1260
phenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
I


6-1261
2-fluorophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
I


6-1262
3-fluorophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
I


6-1263
4-fluorophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
I


6-1282
2,6-difluorophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
I


6-1416
phenyl
H
H
F
H
H
H
F
H
heptafluoroisopropyl
H
CF3


6-1417
phenyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-1418
2-fluorophenyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-1422
3-chlorophenyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-1426
4-bromophenyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-1439
2,6-difluorophenyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-1440
3,4-dichlorophenyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-1441
2,4-dichlorophenyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
C2F5


6-1442
2-chloro-4-fluorophenyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-1445
2-bromo-4-chlorophenyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


6-1446
2-bromo-4-fluorophenyl
H
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


6-1574
phenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1575
2-fluorophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1576
3-fluorophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1577
4-fluorophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1578
2-chlorophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1579
3-chlorophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1580
4-chlorophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1581
2-bromophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1582
3-bromophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1583
4-bromophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1584
2-iodophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1585
3-iodophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1586
4-iodophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1596
2,6-difluorophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1597
3,4-dichlorophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1598
2,4-dichlorophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1599
2-chloro-4-fluorophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1600
2-chloro-4,5-difluorophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1601
4-bromo-2-chlorophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1602
2-bromo-4-chlorophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1603
2-bromo-4-fluorophenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


6-1730
phenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1731
2-fluorophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1732
3-fluorophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1733
4-fluorophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1734
2-chlorophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1735
3-chlorophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1736
4-chlorophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1737
2-bromophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1738
3-bromophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1739
4-bromophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1740
2-iodophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1741
3-iodophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1742
4-iodophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1752
2,6-difluorophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1753
3,4-dichlorophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1754
2,4-dichlorophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1755
2-chloro-4-fluorophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1756
2-chloro-4,5-difluorophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1757
4-bromo-2-chlorophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1758
2-bromo-4-chlorophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-1759
2-bromo-4-fluorophenyl
H
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


6-2110
phenyl
H
H
F
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


6-5902
phenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
Cl


6-5910
phenyl
H
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
C2F5











embedded image





















TABLE A2





compound














number
Q1
R1
R2
X1
X2
X3
X4
Y1
Y2
Y3
Y4
Y5







7-940
phenyl
Me
H
F
H
H
H
F
H
heptafluoroisopropyl
H
F


7-948
phenyl
Me
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
Cl


7-1104
phenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
Br


7-1105
2-fluorophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
Br


7-1106
3-fluorophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
Br


7-1107
4-fluorophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
Br


7-1126
2,6-difluorophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
Br


7-1260
phenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
I


7-1261
2-fluorophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
I


7-1262
3-fluorophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
I


7-1263
4-fluorophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
I


7-1282
2,6-difluorophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
I


7-1416
phenyl
Me
H
F
H
H
H
F
H
heptafluoroisopropyl
H
CF3


7-1417
phenyl
Me
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


7-1441
2,4-dichlorophenyl
Me
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
C2F5


7-1442
2-chloro-4-fluorophenyl
n-Pr
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
CF3


7-1445
2-bromo-4-chlorophenyl
Me
H
F
H
H
H
Cl
H
heptafluoroisopropyl
H
n-C3F7


7-1574
phenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1575
2-fluorophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1576
3-fluorophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1577
4-fluorophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1578
2-chlorophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1579
3-chlorophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1580
4-chlorophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1581
2-bromophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1582
3-bromophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1583
4-bromophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1584
2-iodophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1585
3-iodophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1586
4-iodophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1596
2,6-difluorophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1597
3,4-dichlorophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1598
2,4-dichlorophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1599
2-chloro-4-fluorophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1600
2-chloro-4,5-difluorophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1601
4-bromo-2-chlorophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1602
2-bromo-4-chlorophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1603
2-bromo-4-fluorophenyl
Me
H
F
H
H
H
Br
H
heptafluoroisopropyl
H
CF3


7-1730
phenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1731
2-fluorophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1732
3-fluorophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1733
4-fluorophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1734
2-chlorophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1735
3-chlorophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1736
4-chlorophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1737
2-bromophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1738
3-bromophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1739
4-bromophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1740
2-iodophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1741
3-iodophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1742
4-iodophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1752
2,6-difluorophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1753
3,4-dichlorophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1754
2,4-dichlorophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1755
2-chloro-4-fluorophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1756
2-chloro-4,5-difluorophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1757
4-bromo-2-chlorophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1758
2-bromo-4-chlorophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-1759
2-bromo-4-fluorophenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
CF3


7-2110
phenyl
Me
H
F
H
H
H
CF3
H
heptafluoroisopropyl
H
CF3


7-5902
phenyl
Me
H
F
H
H
H
I
H
heptafluoroisopropyl
H
Br









Hereinbelow, Table A3 shows the physical properties of the representative compounds of the amide derivative according to the present invention. The 1H-NMR chemical shift values shown therein are based on tetramethylsilane as an internal standard substance unless specified otherwise.










TABLE A3





compound



number

1H-NMR (CDCl3, ppm)








6-1104
δ 7.40 (1H, t, J = 7.8 Hz), 7.53-7.64 (3H, m), 7.89 (2H, s), 7.90-7.95 (3H, m), 8.11-8.14 (2H, m),



8.69-8.70 (1H, m).


6-1105
δ 7.22-7.26 (1H, m), 7.35-7.41 (2H, m), 7.58 (1H, d, J = 8.0 Hz), 7.88-7.92 (3H, m), 8.15-8.25 (2H, m),



8.74-8.75 (2H, m).


6-1106
δ 7.35-7.34 (1H, m), 7.417.42 (1H, m), 7.53-7.54 (1H, m), 7.67-7.68 (2H, m), 7.89-7.90 (3H, m),



8.09-8.10 (2H, m), 8.66-8.68 (1H, m).


6-1107
δ 7.21-7.26 (2H, m), 7.39-7.41 (1H, m), 7.89-7.96 (4H, m), 8.05-8.13 (3H, m), 8.70-8.72 (1H, m).


6-1126
δ 7.05-7.09 (2H, m), 7.38-7.42 (1H, m), 7.49-7.50 (1H, m), 7.88-7.99 (4H, m), 8.09-8.12 (1H, m),



8.71-8.72 (1H, m).


6-1260
δ 7.39 (1H, t, J = 7.8 Hz), 7.52-7.57 (4H, m), 7.60-7.63 (2H, m), 7.93-7.94 (4H, m), 8.70 (1H, t, J = 6.3 Hz).


6-1261
δ 7.22-7.28 (1H, m), 7.35-7.42 (2H, m), 7.59-7.61 (1H, m), 7.94-7.95 (1H, m), 8.12 (2H, s), 8.15-8.25 (2H,



m), 8.78 (1H, t, J = 1.5 Hz), 9.00 (1H, d, J = 7.8 Hz).


6-1262
δ 7.30-7.33 (1H, m), 7.40-7.44 (1H, m), 7.52-7.55 (2H, m), 7.64-7.70 (3H, m), 7.95-7.96 (1H, m),



8.09-8.13 (2H, m), 8.67-8.68 (1H, m).


6-1263
δ 7.20-7.26 (3H, m), 7.38-7.42 (1H, m), 7.91-7.98 (3H, m), 8.07-8.12 (3H, m), 8.63-8.67 (1H, m).


6-1282
δ 7.06 (2H, t, J = 8.3 Hz), 7.38-7.42 (1H, m), 7.47-7.52 (1H, m), 7.93-7.97 (1H, m), 8.01 (1H, s),



8.11-8.13 (3H, m), 8.68-8.72 (1H, m).


6-1574
δ 7.37-7.41 (1H, m), 7.53-7.64 (3H, m), 7.86-7.94 (4H, m), 8.13-8.22 (3H, m), 8.67-8.72 (1H, m).


6-1575
δ 7.22-7.27 (1H, m), 7.35-7.41 (2H, m), 7.57-7.60 (1H, m), 7.88-7.93 (2H, m), 8.16 (1H, s), 8.20-8.25 (2H,



m), 8.74-8.75 (1H, m), 8.77-9.00 (1H, m).


6-1576
δ 7.27-7.37 (2H, m), 7.48-7.53 (1H, m), 7.72-7.80 (3H, m), 7.92 (1H, s), 8.15 (1H, s), 8.27-8.31 (1H, m),



9.16 (1H, s), 9.35 (1H, d, J = 7.3 Hz).


6-1577
δ 7.20-7.23 (3H, m), 7.24-7.26 (1H, m), 7.39-7.40 (3H, m), 7.86-7.97 (1H, m), 8.06 (1H, d, J = 2.4 Hz),



8.16-8.20 (1H, m), 8.62-8.67 (1H, m).


6-1596
δ 7.00-7.09 (2H, m), 7.40-7.41 (1H, m), 7.46-7.53 (1H, m), 7.89-7.92 (2H, m), 8.00 (1H, s),



8.16-8.19 (2H, m), 8.71-8.72 (1H, m).


6-1730
δ 7.40 (1H, t, J = 7.8 Hz), 7.53-7.64 (3H, m), 7.87-7.95 (4H, m), 8.14 (1H, s), 8.22 (1H, d, J = 12.7 Hz),



8.37 (1H, s), 8.71-8.72 (1H, m).


6-1731
δ 7.22-7.25 (1H, m), 7.35-7.37 (2H, m), 7.58-7.60 (1H, m), 7.90 (1H, t, J = 8.6 Hz), 7.96 (1H, s), 8.22 (1H, t, J = 8.8 Hz),



8.29-8.32 (1H, d, J = 12.4 Hz), 8.37 (1H, s), 8.73 (1H, m), 8.94 (1H, s).


6-1732
δ 7.32-7.33 (1H, m), 7.37 (1H, t, J = 8.0 Hz), 7.52-7.54 (1H, m), 7.64-7.70 (2H, m), 7.90 (1H, t, J = 6.4 Hz),



7.96 (1H, s), 8.10 (1H, s), 8.23 (1H, d, J = 12.0 Hz), 8.37 (1H, s), 8.65 (1H, t, J = 8.0 Hz).


6-1733
δ 7.19-7.25 (2H, m), 7.35 (1H, t, J = 7.8 Hz), 7.87-7.97 (4H, m), 8.08 (1H, s), 8.25 (1H, d, J = 12.0 Hz), 8.37 (1H,



s), 8.65 (1H, t, J = 8.0 Hz).


6-1734
δ 7.43-7.52 (5H, m), 7.87-7.95 (3H, m), 8.22 (1H, d, J = 10.0 Hz), 8.35 (1H, d, J = 8.2 Hz), 8.74 (1H, t, J = 8.4 Hz).


6-2110
δ 7.36-7.40 (1H, m), 7.53-7.64 (3H, m), 7.84-7.97 (1H, m), 7.92-7.94 (2H, m), 8.04-8.07 (1H, m),



8.08-8.13 (1H, m), 8.20 (2H, s), 8.68-8.72 (1H, m).


6-5902
(DMSO-d6) δ 7.39 (1H, t, J = 7.8 Hz), 7.52-7.64 (4H, m), 7.81 (1H, t, J = 6.8 Hz), 7.95 (1H, s), 7.98-8.01 (3H,



m), 10.29 (1H, s), 10.68 (1H, s).


6-5910
δ 7.39 (1H, t, J = 8.3 Hz), 7.53-7.64 (3H, m), 7.88-7.94 (4H, m), 8.13 (1H, broad-s), 8.19 (1H, broad-s),



8.24 (1H, d, J = 13.2 Hz), 8.70-8.72 (1H, m).


7-948
δ 3.49 (3H, s), 7.23-7.52 (8H, m), 7.66 (2H, s), 8.00 (1H, t, J = 6.8 Hz).


7-1104
δ 3.51 (3H, s), 7.22-7.44 (7H, m), 7.86 (2H, s), 8.00-8.03 (2H, m).


7-1105
δ 3.52 (3H, s), 6.82 (1H, t, J = 8.8 Hz), 7.06-7.08 (1H, m), 7.18-7.24 (2H, m), 7.40-7.44 (2H, m), 7.87 (3H, s),



8.01-8.05 (1H, m).


7-1106
δ 3.50 (3H, s), 7.00-7.23 (4H, m), 7.29-7.31 (1H, m), 7.45 (1H, s), 7.87 (3H, s), 8.03-8.07 (1H, m).


7-1107
δ 3.49 (3H, s), 6.91-6.93 (2H, m), 7.28-7.44 (4H, m), 7.86 (2H, s), 8.00-8.10 (2H, m).


7-1126
δ 3.49 (3H, s), 6.72-6.76 (2H, m), 7.16-7.23 (2H, m), 7.43-7.50 (1H, m), 7.88 (2H, s), 8.02-8.06 (1H, m),



8.13-8.17 (1H, m).


7-1260
δ 4.09 (3H, s), 7.21-7.49 (7H, m), 7.99-8.08 (4H, m).


7-1261
δ 3.53 (3H, s), 6.79-6.83 (1H, m), 7.03-7.07 (1H, m), 7.19-7.23 (2H, m), 7.42-7.43 (2H, m), 8.01-8.10 (4H,



m).


7-1417
δ 3.49 (3H, s), 7.23-7.26 (3H, m), 7.27-7.33 (3H, m), 7.52-7.53 (1H, m), 7.85 (1H, s), 7.96-8.06 (3H, m).


7-1574
δ 3.50 (3H, s), 6.99-7.33 (6H, m), 7.43-7.45 (1H, m), 7.90 (1H, s), 7.97-8.06 (2H, m), 8.13 (1H, s).


7-1575
δ 3.52 (3H, s), 6.82-6.83 (1H, m), 7.06-7.07 (1H, m), 7.19-7.26 (2H, m), 7.39-7.46 (2H, m), 7.91 (1H, s),



7.99-8.01 (1H, m), 8.07-8.14 (2H, m).


7-1576
δ 3.50 (3H, s), 7.01-7.17 (4H, m), 7.27-7.31 (1H, m), 7.46-7.52 (1H, m), 7.91 (1H, s), 8.01-8.05 (2H, m),



8.13 (1H, s).


7-1577
δ 3.50 (3H, s), 6.90-6.94 (2H, m), 7.26-7.35 (3H, m), 7.45-7.46 (1H, m), 7.90 (1H, s), 8.00-8.07 (2H, m),



8.13 (1H, s).


7-1596
δ 3.54 (3H, s), 6.75 (2H, broad-s), 7.17-7.26 (2H, m), 7.50-7.51 (1H, m), 7.92 (1H, s), 8.01-8.05 (1H, m),



8.14-8.20 (2H, m).


7-1730
δ 3.51 (3H, s), 7.21-7.23 (2H, m), 7.27-7.33 (4H, m), 7.44-7.46 (1H, m), 7.92 (1H, s), 8.00 (1H, t, J = 6.3 Hz),



8.08-8.09 (1H, m), 8.33 (1H, s).


7-1731
δ 3.51 (3H, s), 6.79-6.83 (1H, m), 7.05 (1H, t, J = 7.6 Hz), 7.18-7.46 (4H, m), 7.94-8.00 (2H, m), 8.20 (1H, d, J = 12.4 Hz),



8.34 (1H, s).


7-1732
δ 3.50 (3H, s), 7.00-7.18 (4H, m), 7.27-7.31 (1H, m), 7.45-7.48 (1H, m), 7.93 (1H, s), 8.01-8.03 (1H, m),



8.12 (1H, broad-s), 8.34 (1H, s).


7-1733
δ 3.50 (3H, s), 6.91 (2H, s), 6.93-7.35 (3H, m), 7.47 (1H, t, J = 7.0 Hz), 7.93 (1H, s), 8.01-8.10 (1H, m), 8.13 (1H,



broad-s), 8.34 (1H, s).


7-1752
δ 3.54 (3H, s), 6.74 (2H, s), 7.16-7.24 (2H, m), 7.50 (1H, t, J = 7.4 Hz), 7.94 (1H, s), 8.01-8.05 (1H, m), 8.25 (1H,



broad-s), 8.35 (1H, s).


7-5902
δ 3.51 (3H, s), 7.00-7.52 (7H, m), 7.88 (1H, d, J = 1.5 Hz), 8.01-8.06 (3H, m).









In particular, for example, animal parasites that can be exterminated by the composition for exterminating animal parasites according to the invention include the followings, although the invention is not limited thereto. The ectoparasites include Siphonaptera pests such as Ctenocephalides felis, Ctenocephalides canis, Xenopsylla cheopis, Echidnophaga gallinacea), and Pulex irritans;


acarine pests such as Haemaphyxalislongicornis, Haemaphysalis japonica, Rhipicephalus sanguineus, Boophilus microplus, Dermacentor recticulatus, Dermacentor taiwanensis, Haemaphysalis flava, Ixodes ovatus, Ixodes persulcatus, Amblyomma americanum, Amblyomma maculatum, Dermacentor andersoni, Dermacentor occidentalis, Dermacentor variabilis, Haemaphysalis campanulata, Haemaphysalis megaspinosa, Ixodes nipponensis, Ixodes pacifcus, Ixodes ricinus, and Ixodes scapularisand;


dipterous pests such as Musca hervei, Musca bezzii, Haematobia irritans, Simulium iwatens, Culicoides oxystoma, Tabanus chrysurus, Culex pipiens, and Aedes albopictus;


Phthiraptera pests such as Haematopinus eurysternus and Damalinia ovis; and the like.


The endoparasites include:


Protozoa such as Rhizopoda including Endamoeba histolytica, Mastigophora including Leishmania and Tichomonas, Sporozoea including Plasmodium and Toxoplasma, and Ciliophora including Balantidium coli;


helminths such as Nematoda including Ascaris lumbricoides and Ancylostoma, Acannthocephala including Macracanthorhynchus hirudinaceus, Nematomorpha including Paragordius tricuspidatus, Tematoda including Clonorchis sinensis, and Cestoda including Taenia saginata;


nematodes such as Ascaris, Toxocara, Toxascaris, Parascaris, Ascaridia, Heterakis, Oxyuris, Capillaria, Trichinella, Strongylus, Triodontophorus, Trichonema, Stephanurus, Desophagostomum, Chabertia, Syngamus, Ancylostoma, Uncinaria, Necator, Bunostomum, Trichostrongylus, Cooperia, Nematodirus, Haemonchus, Ostertagia, Dictyocaulus, Metastrongylus, Dirofilaria, Parafilaria, Setaria, Onchocerca, Habronema, Arduenna, and Acuaria;


cestodes such as Diphyllobothrium, Anoplocephara, Moniezia, Dipylidium, Taenia, Dithyridium, Raillietina, and Echinococcus;


flukes such as Schistosoma, Paramphistomum, and Fasciola; and the like.


In the invention, said animal parasites are preferably ectoparasites from the viewpoint of parasiticidal activity, and they are preferably at least one of Siphonaptera pests (especially preferably Ctenocephalides felis) and Acarina pests (especially preferably Haemaphyxalislongicornis, Rhipicephalus sanguineus, and Boophilus microplus).


The animals to which the composition for exterminating animal parasites according to the invention can be applied include domestic animals such as human, horses, cows, pigs, sheep, goats, rabbits, camels, buffalos, deer, minks, and chinchillas; fowls such as chickens, ducks, geese, and turkeys; pets such as dogs, cats, small birds, and monkeys; laboratory animals such as rats, mice, golden hamsters, and guinea pigs; and the like, although the invention is not limited thereto.


The composition for exterminating animal parasites according to the invention can be used as a parasiticide by any of the methods normally used, with no particular restriction.


In particular, for example, the composition may be dissolved, suspended, mixed, impregnated, adsorbed, or adhered on suitable solid and/or liquid carriers according to a formulation generally used, and, if required, together with adjuvant in a suitable proportion. And the composition may be prepared into an appropriate form in accordance with the intended use.


The solid or liquid carrier for use in the invention may be those normally used in agents for animals. From the viewpoint of easiness of treatment on the target animals, it is preferable to use a liquid carrier. The liquid carrier includes, for example, alcohol such as methyl alcohol, ethyl alcohol, isopropyl alcohol, tertiary butyl alcohol, and benzyl alcohol; propylene carbonate; N-methyl-2-pyrrolidone; water, and the like. As the adjuvant, surfactant, antioxidant, emulsifier, and the like can be used. The adjuvant can include, for example, surfactant such as polyoxyethylene alkylaryl ether, polyoxyethylene sorbitan monolaurate, alkyl allyl sorbitan monolaurate, alkylbenzenesulfonate, alkylnaphthalene sulfonic acid, ligninsulfonic acid salts, higher alcohol sulfate salts, glycol monoalkyl ethers, and glycols; emulsifier such as sorbitan monooleate, sorbitan monolaurate, caprylic acid monoglyceride, capric acid monoglyceride, isostearic acid monoglyceride, and propylene glycol monocaprylate; and antioxidant such as BHA and BHT.


The composition for exterminating animal parasites according to the invention may be administered orally or parenterally to an animal.


If the composition for exterminating animal parasites according to the invention is administered orally, the composition may be in the form of capsules, tablets, pills, powders, granules, fine granules, syrups, enteric agents, suspensions, paste, or beverage or feeds mixed with the drug.


If the composition for exterminating animal parasites according to the invention is administered parenterally, the composition may be in the form of injectables, drips, suppositories, emulsions, suspensions, drops, ointments, creams, solutions, lotions, sprays, aerosols, cataplasms, and tapes.


The method for administration includes the spot-on method in which drops are dropped on the skin of the back shoulder region and the like of the target animal to exterminate ectoparasites; local methods such as the pour-on method in which a liquid agent is applied along the back center line of the target animal to allow the applied agent to diffuse on the body surface, resulting in control of ectoparasites; the methods in which the agent is released from a collar containing the agent; the methods in which a liquid agent, ointment, or the like is directly applied to the body surface; the methods in which an aerosol or the like is applied with a spray or the like; the methods in which an injectable is injected intramuscularly, subcutaneously, or the like; and rectal administration with a suppository.


In addition to extermination of endoparasites and exoparasites, the composition for exterminating animal parasites according to the invention also can prophylactically prevent parasitic infections by applying it to the environments which are to be the infection routes. For example, the composition can prevent soil infections from soils of upland fields and parks; percutaneous infections from aqueous systems such as river, lake, wetland, and paddy field; oral infections from excrements of animals such as dogs and cats; and oral infections from raw meats of sea water fish, fresh water fish, Crustaceae, shellfish, domestic animals, and the like; and infections from mosquitoes, horseflies, flies, cockroaches, ticks, fleas, lice, assassin bugs, chiggers, etc.; and the like.


If the composition for exterminating animal parasites according to the invention is used to exterminate parasites in the animals that are mammals or birds, the optimal dosage varies depending on whether it is used for therapeutic purposes or for preventive purposes, and also varies with the type of infected parasites, the type and extent of infection, dosage form, etc. But generally, in case of oral administration, the dosage is in the range from about 0.0001 to 10,000 mg per kilogram of body weight per day. In case of parenteral administration, the dosage is in the range from about 0.0001 to 10,000 mg per kilogram of body weight per day, and the composition is administered in single or in divided doses.


The concentration of the active ingredient in the composition for exterminating animal parasites according to the invention is typically from 0.0001 to 100% by weight, preferably from 0.001 to 99% by weight, and more preferably from 0.005 to 80% by weight. In general, the parasiticides may be provided as a high-concentrated composition to be diluted to the appropriate concentration prior to use.


In addition to the amide derivatives represented by Formula (1) according to the invention, the composition for exterminating animal parasites according to the invention can further contain other insecticidal components that are generally known. The other insecticidal components can include, for example, pyrethroid compounds such as permethrin, d-phenothrin, allethrin, pyrethrum, prallethrin, cyphenothrin, cyfluthrin, fenvalerate, fenpropathrin, transfluthrin, metofluthrin, resmethrin, cypermethrin, alpha-cypermethrin, bifenthrin, deltamethrin, lambda-cyhalothrin, d,d-trans-cyphenothrin, tetramethrin, and ethofenprox; organic phosphorus compounds such as dichlorvos, tetrachlorvinphos, fenthion, chlorpyrifos, chlorpyrifos-methyl, malathion, pirimiphos-methyl, fenitrothion, and diazinon; N-phenylpyrazole compounds such as fipronil; carbamate compounds such as propoxur, carbaryl, metoxadiazone, and fenocarb; neonicotinoid compounds such as imidacloprid, clothianidin, thiamethoxam, acetamiprid, nitenpyram, and dinotefuran; growth inhibitors for insect such as methoprene, pyriproxyfen, lufenuron, fenoxycarb, triflumuron, and chromafenozide; milbemycin oxime; milbemectin; lepimectin; abamectin; ivermectin; selamectin; spinosad; rotenone; and the like.


The disclosure of Japanese Patent Application JP 2010-019747 is incorporated herein in its entirety.


All publications, patent applications, and technical specifications cited herein are incorporated herein by reference to the same extent as if each individual publication, patent application, and technical specification were specifically and individually indicated to be incorporated by reference.


EXAMPLES

Representative Examples of the present invention will be described with reference to the following Examples, but the present invention is not limited thereto. In the present Examples, DMF means N,N-dimethyl formamide, THF means tetrahydrofuran, IPE means isopropyl ether, and DMI means 1,3-dimethyl-2-imidazolidinone. Furthermore, “%” is based on mass unless specified otherwise.


Example 1
Preparation of N-(2-bromo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-2-fluoro-3-(N-methylbenzamide)benzamide (Compound No. 7-1574)



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1-1>


Preparation of 4-(heptafluoropropan-2-yl)-2-(trifluoromethyl)aniline



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100 g (0.608 mol) of 2-(trifluoromethyl)aniline, 131 g (0.639 mol) of 85% sodium hydrosulfite, and 20.9 g (0.0608 mol) of tetrabutylammonium hydrogen sulfate were charged to a mixed solution of 1500 ml of ethyl acetate and 1500 ml of water, and 53.9 g (0.639 mol) of sodium hydrogen carbonate was added thereto. 198 g (0.669 mol) of heptafluoroisopropyl iodide was added dropwise thereto at room temperature, followed by stirring at room temperature for 6 hours. After the liquid separation, the solvent of the organic layer was evaporated under reduced pressure, and 500 ml of ethyl acetate was charged thereto. 160 g (0.608 mol) of a 4 M hydrogen chloride/ethyl acetate solution was added dropwise thereto, followed by stirring at room temperature for 30 minutes, and then stirring at 5° C. for 1 hour. After the filtration, the filtrate was washed with water and a saturated aqueous sodium hydrogen carbonate in this order, and then dried over anhydrous magnesium sulfate, and the solvent was evaporated under reduced pressure. The obtained residue was purified by silica gel column chromatography (eluent solvent; hexane:ethyl acetate=10:1) to prepare 60.0 g (yield 30%) of a target compound.



1H-NMR (CDCl3, ppm) δ 4.49 (2H, broad-s), 6.81 (1H, d, J=8.3 Hz), 7.48 (1H, d, J=8.3 Hz), 7.64 (1H, s).


<1-2>


Preparation of 2-bromo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)aniline



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100 g (0.273 mol) of 4-(heptafluoropropan-2-yl)-2-(trifluoromethyl)aniline was charged to 500 ml of DMF, and 52.1 g (0.287 mol) of N-bromosuccinimide was charged in separate portions thereto over 30 minutes. After stirring at 60° C. for 2 hours, and then cooling to room temperature, the mixture was discharged to 2000 ml of water. The mixture was extracted with ethyl acetate, then washed with saturated brine, and dried over anhydrous magnesium sulfate. The solvent was evaporated under reduced pressure and the obtained residue was purified by silica gel column chromatography (eluent solvent; hexane:ethyl acetate=20:1) to prepare 89.0 g (yield 80%) of a target compound.



1H-NMR (CDCl3, ppm) δ 5.03 (2H, broad-s), 7.61 (1H, s), 7.79 (1H, s).


<1-3>


Preparation of N-(2-bromo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-2-chloro-3-nitrobenzamide



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3.60 g (8.82 mmol) of 2-bromo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)aniline was charged to 20 ml of anhydrous THF, and cooled to −70° C. under a nitrogen atmosphere. 4.85 ml (9.70 mmol) of a 2.0 M lithium diisopropyl amide hexane solution was added dropwise thereto, then 2.34 g (10.7 mmol) of acid chloride which was prepared from 2-chloro-3-nitrobenzoic acid and thionyl chloride was dissolved in 5 ml of anhydrous TIF, and was added dropwise thereto, followed by stirring at −70° C. for 30 minutes and then stirring at room temperature for 30 minutes. The mixture was discharged to an aqueous ammonium chloride solution, then extracted with ethyl acetate, and dried over anhydrous magnesium sulfate. The solvent was evaporated under reduced pressure and the obtained residue was purified by silica gel column chromatography (eluent solvent; hexane:ethyl acetate=10:1→8:2→3:1) to prepare 1.76 g (yield: 34%) of a target compound.



1H-NMR (CDCl3, ppm) δ 7.61 (1H, t, J=7.8 Hz), 7.67 (1H, broad-s), 7.93-7.97 (3H, m), 8.18 (1H, broad-s).


<1-4>


Preparation of N-(2-bromo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-2-fluoro-3-nitrobenzamide



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To a solution of N-(2-bromo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-2-chloro-3-nitrobenzamide 4.89 g (8.27 mmol) in 50 ml of anhydrous DMF was added 2.40 g (41.3 mmol) of potassium fluoride (spray-dried product) under a flow of nitrogen, followed by stirring at 130° C. for 10 hours. Liquid separation was carried out by adding ethyl acetate, hexane, and water to the reaction mixture, and then the organic layer was washed with water and saturated brine, and dried over anhydrous magnesium sulfate. The solvent was evaporated under reduced pressure and the obtained residue was purified by silica gel column chromatography (eluent solvent; hexane:ethyl acetate=10:1) to prepare 0.940 g (yield 20%) of a target compound.



1H-NMR (CDCl3, ppm) δ 7.53 (1H, t, J=7.3 Hz), 7.93 (1H, broad-s), 8.17-8.18 (2H, m), 8.28-8.32 (1H, m), 8.44-8.48 (1H, m).


<1-5>


Preparation of 3-amino-N-(2-bromo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-2-fluorobenzamide



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0.940 g (1.63 mmol) of N-(2-bromo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-2-fluoro-3-nitrobenzamide and 0.960 g (5.05 mmol) of stannous chloride (anhydrous) were added to 10 ml of ethanol, and 1.02 ml (9.78 mmol) of concentrated hydrochloric acid was added thereto, followed by stirring at 60° C. for 4 hours. The reaction mixture was adjusted to pH 10 by the addition of an aqueous sodium hydroxide solution, and the precipitated insolubles were removed by filtration using Celite. The filtrate on Celite was washed with ethyl acetate. The filtrate was extracted with ethyl acetate, and the organic layer was washed with a 20% aqueous sodium hydroxide solution and saturated brine, and then dried over anhydrous magnesium sulfate. The solvent was evaporated under reduced pressure and the obtained residue was purified by silica gel column chromatography (eluent solvent; hexane:ethyl acetate=4:1) to prepare 0.930 g (yield 99%) of a target compound.



1H-NMR (CDCl3, ppm) δ 3.93 (2H, broad-s), 6.99-7.04 (1H, m), 7.11 (1H, t, J=7.8 Hz), 7.47-7.49 (1H, m), 7.91 (1H, s), 8.14 (1H, s), 8.28 (1H, d, J=14.6 Hz).


<1-6>


Preparation of N-(2-bromo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-2-fluoro-3-(methylamino)benzamide



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0.930 g (1.71 mmol) of 3-amino-N-(2-bromo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-2-fluorobenzamide was added to 5 ml of concentrated sulfuric acid, and 10 ml of a 37% aqueous formaldehyde solution was charged dropwise thereto at 40° C. The reaction mixture was poured into ice-water, adjusted to pH 10 using an aqueous sodium hydroxide solution, and extracted with the addition of ethyl acetate. The organic layer was washed with a 20% aqueous sodium hydroxide solution and saturated brine, and then dried over anhydrous magnesium sulfate. The solvent was evaporated under reduced pressure and the obtained residue was purified by silica gel column chromatography (eluent solvent; hexane:ethyl acetate=8:1) to prepare 0.690 g (yield 72%) of a target compound.



1H-NMR (CDCl3, ppm) δ 2.94 (3H, s), 4.14 (1H, broad-s), 6.88-6.93 (1H, m), 7.18 (1H, t, J=7.8 Hz), 7.37-7.41 (1H, m), 7.90 (1H, s), 8.13 (1H, s), 8.27 (1H, d, J=14.6 Hz).


<1-7> Preparation of N-(2-bromo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-2-fluoro-3-(N-methylbenzamide)benzamide (Compound No. 7-1574)



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To a solution of 1.54 g (2.75 mmol) of N-(2-bromo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-2-fluoro-3-(methylamino)benzamide and 0.330 g (4.13 mmol) of pyridine in 5 ml of THF was added 0.460 g (3.30 mmol) of benzoyl chloride, followed by stirring at 60° C. for 5 hours. To the reaction mixture were added water and ethyl acetate, and the organic layer was washed with 1 M hydrochloric acid, a saturated aqueous sodium hydrogen carbonate solution, and saturated brine, and then dried over anhydrous magnesium sulfate. The solvent was evaporated under reduced pressure and the obtained residue was purified by silica gel column chromatography (eluent solvent; hexane:ethyl acetate=8:1), and the obtained solid was washed with IPE to prepare 1.45 g (yield 80%) of a target compound.



1H-NMR (CDCl3, ppm) δ 3.50 (3H, s), 6.99-7.33 (6H, m), 7.43-7.45 (1H, m), 7.90 (1H, s), 7.97-8.06 (2H, m), 8.13 (1H, s).


Example 2
Preparation of N-(2,6-dibromo-4-(heptafluoropropan-2-yl)phenyl)-2-fluoro-3-(N-methylbenzamide)benzamide (Compound No. 7-1104)



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<2-1>


Preparation of 4-(heptafluoropropan-2-yl)aniline



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100 g (1.02 mol) of aniline, 230 g (1.12 mol) of 85% sodium hydrosulfite, and 35.1 g (0.100 mol) of tetrabutylammonium hydrogen sulfate were charged to a mixed solution of 1500 ml of t-butyl methyl ether and 1500 ml of water, and 94.7 g (1.12 mol) of sodium hydrogen carbonate was added thereto. 350 g (1.12 mol) of heptafluoroisopropyl iodide was added dropwise thereto at room temperature, followed by stirring at room temperature for 6 hours. After the liquid separation, the organic layer was washed with 1 M hydrochloric acid, water, and a saturated aqueous sodium hydrogen carbonate solution, and then dried over anhydrous sodium sulfate. The solvent was evaporated under reduced pressure, and 500 ml of ethyl acetate was charged thereto. 255 g (1.02 mol) of a 4 M hydrogen chloride/ethyl acetate solution was added dropwise thereto, followed by stirring at room temperature for 30 minutes and at 5° C. for 1 hour. The precipitated solid was separated by filtration, and the solid was charged to 1000 ml of ethyl acetate, adjusted to pH 8 to 9 by the addition of 1000 ml of a saturated aqueous sodium hydrogen carbonate solution at 20° C. or lower, and subjected to liquid separation. The organic layer was dried over anhydrous sodium sulfate, and then the solvent was evaporated under reduced pressure to prepare 188 g (yield 71%) of a target compound.



1H-NMR (CDCl3, ppm) δ 3.92 (2H, broad-s), 6.69-6.74 (2H, m), 7.35 (2H, d, J-=9.3 Hz).


<2-2>


Preparation of 2,6-dibromo-4-(heptafluoropropan-2-yl)aniline



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216 g (0.802 mol) of 4-(heptafluoropropan-2-yl)aniline was charged to 863 ml of DMF, followed by cooling to 5° C. 285 g (1.60 mol) of N-bromosuccinimide was charged in separate portions thereto over 1 hour. The mixture was stirred at room temperature for 1 hour and then stirred at 37° C. for 2 hours. The mixture was discharged to 2000 ml of water, extracted with 2000 ml of ethyl acetate, and washed with 1000 ml of saturated brine. After dried over anhydrous magnesium sulfate, the solvent was evaporated under reduced pressure. The obtained residue was purified by silica gel column chromatography (eluent solvent; hexane:ethyl acetate=20:1) to prepare 304 g (yield 90%) of a target compound.



1H-NMR (CDCl3, ppm) δ 4.88 (2H, broad-s), 7.59 (2H, s).


<2-3>


Preparation of 2-chloro-N-(2,6-dibromo-4-(heptafluoropropan-2-yl)phenyl)-3-nitrobenzamide



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According to the method of 1-3 of Example 1, a target compound was prepared from 2,6-dibromo-4-(heptafluoropropan-2-yl)aniline.



1H-NMR (CDCl3, ppm) δ 7.58 (1H, t, J=7.8 Hz), 7.66 (1H, broad-s), 7.90 (2H, s), 7.93 (1H, dd, J=1.5, 7.8 Hz), 7.98 (1H, d, J=7.8 Hz).


<2-4>


Preparation of N-(2,6-dibromo-4-(heptafluoropropan-2-yl)phenyl)-2-fluoro-3-nitrobenzamide



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According to the method of 1-4 of Example 1, a target compound was prepared from 2-chloro-N-(2,6-dibromo-4-(heptafluoropropan-2-yl)phenyl)-3-nitrobenzamide.



1H-NMR (CDCl3, ppm) δ 7.51-7.55 (1H, m), 7.90 (2H, s), 8.16 (1H, d, J=11.7 Hz), 8.27-8.31 (1H, m), 8.48 (1H, t, J=6.3 Hz).


<2-5>


Preparation of 3-amino-N-(2,6-dibromo-4-(heptafluoropropan-2-yl)phenyl)-2-fluorobenzamide



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According to the method of 1-5 of Example 1, a target compound was prepared from N-(2,6-dibromo-4-(heptafluoropropan-2-yl)phenyl)-2-fluoro-3-nitrobenzamide.



1H-NMR (CDCl3, ppm) δ 3.93 (2H, broad-s), 6.99-7.04 (1H, m), 7.11 (1H, t, J=7.8 Hz), 7.47-7.49 (1H, m), 7.91 (1H, s), 8.14 (1H, s), 8.28 (1H, d, J=14.6 Hz).


<2-6>


Preparation of N-(2,6-dibromo-4-(heptafluoropropan-2-yl)phenyl)-2-fluoro-3-(methylamino)benzamide



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According to the method of 1-6 of Example 1, a target compound was prepared from 3-amino-N-(2,6-dibromo-4-(heptafluoropropan-2-yl)phenyl)-2-fluorobenzamide.



1H-NMR (CDCl3, ppm) δ 2.94 (3H, d, J=5.6 HZ), 4.87-4.91 (1H, m), 6.91 (1H, t, J=7.9 Hz), 7.18 (1H, t, J=7.9 Hz), 7.41 (11H, t, J=7.1 Hz), 7.87 (2H, s), 8.20 (11H, d, J=13.5 Hz).


<2-7>


Preparation of N-(2,6-dibromo-4-(heptafluoropropan-2-yl)phenyl)-2-fluoro-3-(N-methylbenzamide)benzamide (Compound No. 7-1104)



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According to the method of 1-7 of Example 1, a target compound was prepared from N-(2,6-dibromo-4-(heptafluoropropan-2-yl)phenyl)-2-fluoro-3-(methylamino)benzamide and benzoyl chloride.



1H-NMR (CDCl3, ppm) δ 3.51 (3H, s), 7.22-7.44 (7H, m), 7.86 (2H, s), 8.00-8.03 (2H, m).


Example 3
Preparation of 3-benzamide-2-fluoro-N-(4-(heptafluoropropan-2-yl)-2,6-bis(trifluoromethyl)phenyl)benzamide (Compound No. 6-2110)



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<3-1>


Preparation of 2,6-diiodo-4-(heptafluoropropan-2-yl)aniline



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To a solution of 5.74 g (22.0 mmol) of 4-(heptafluoropropan-2-yl)aniline obtained in 2-1 of Example 2 in 50 ml of ethanol was added 2.16 g (22.0 mmol) of concentrated sulfuric acid at 5° C. The reaction mixture was warmed to room temperature, and 10.0 g (44.0 mmol) of N-iodosuccinimide was added thereto, followed by stirring for 3 hours. The reaction mixture was neutralized with a saturated aqueous sodium hydrogen carbonate solution. The precipitated crystals were filtered, washed with water, and then dried to prepare 9.00 g (yield 80%) of a target compound.



1H-NMR (CDCl3, ppm) δ 4.95 (2H, broad-s), 7.79 (2H, s).


<3-2>


Preparation of 2-chloro-N-(2,6-diiodo-4-(heptafluoropropan-2-yl)phenyl)-3-nitrobenzamide



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To a solution of 40.0 g (78.0 mmol) of 2,6-diiodo-4-(heptafluoropropan-2-yl)aniline in 100 ml of DMI was added 20.6 g (94.0 mmol) of 2-chloro-3-nitrobenzoyl chloride, followed by stirring at 135° C. for 3 hours. After cooling to room temperature, the reaction mixture was poured into 1000 ml of water. After extraction with the addition of 1000 ml of ethyl acetate, the organic layer was washed with water and then dried over anhydrous magnesium sulfate. The solvent was evaporated under reduced pressure and the obtained residue was washed with hexane to prepare 56.2 g (yield 99%) of a target compound. 1H-NMR (CDCl3, ppm) δ 7.58 (1H, t, J=8.3 Hz), 7.70 (1H, d, J=3.4 Hz), 7.93 (1H, dd, J=1.5, 6.3 Hz), 8.08-8.10 (1H, m), 8.13 (2H, s).


<3-3>


Preparation of N-(2,6-diiodo-4-(heptafluoropropan-2-yl)phenyl)-2-fluoro-3-nitrobenzamide



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According to the method of 1-4 of Example 1, a target compound was prepared from 2-chloro-N-(2,6-diiodo-4-(heptafluoropropan-2-yl)phenyl)-3-nitrobenzamide.



1H-NMR (CDCl3, ppm) δ 7.52-7.55 (1H, m), 8.12-8.18 (3H, m), 8.29-8.32 (1H, m), 8.48-8.51 (1H, m).


<3-4>


Preparation of 3-amino-N-(2,6-diiodo-4-(heptafluoropropan-2-yl)phenyl)-2-fluorobenzamide



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According to the method of 1-5 of Example 1, a target compound was prepared from N-(2,6-diiodo-4-(heptafluoropropan-2-yl)phenyl)-2-fluoro-3-nitrobenzamide.



1H-NMR (CDCl3, ppm) δ 3.93 (2H, broad-s), 6.99-7.04 (1H, m), 7.08 (1H, t, J=7.8 Hz), 7.39-7.43 (1H, m), 8.10 (2H, s), 8.72 (1H, d, J=11.2 Hz).


<3-5>


Preparation of 3-benzamide-N-(2,6-diiodo-4-(heptafluoropropan-2-yl)phenyl)-2-fluorobenzamide (Compound No. 6-1260)



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According to the method of 1-7 of Example 1, a target compound was prepared from 3-amino-N-(2,6-diiodo-4-(heptafluoropropan-2-yl)phenyl)-2-fluorobenzamide.



1H-NMR (CDCl3, ppm) δ 7.39 (1H, t, J=7.8 Hz), 7.52-7.57 (4H, m), 7.60-7.63 (2H, m), 7.93-7.94 (4H, m), 8.70 (1H, t, J=6.3 Hz).


<3-6>


Preparation of 3-benzamide-2-fluoro-N-(4-(heptafluoropropan-2-yl)-2,6-bis(trifluoromethyl)phenyl)benzamide (Compound No. 6-2110)



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A solution of 1.95 g (2.59 mmol) of 3-benzamide-N-(2,6-diiodo-4-(heptafluoropropan-2-yl)phenyl)-2-fluorobenzamide, 0.10 g (0.520 mmol) of copper iodide, and 1.24 g (6.48 mmol) of methyl fluorosulfonyl difluoroacetate in 50 ml of DMF was stirred at 100° C. for 6 hours. The reaction mixture was cooled to room temperature, and then 10 ml of water and 100 ml of ethyl acetate were added thereto, followed by filtration through Celite. The organic layer of the liquid was washed with water and a saturated aqueous sodium hydrogen carbonate solution, and then dried over anhydrous magnesium sulfate. The solvent was evaporated under reduced pressure and the obtained residue was purified by silica gel column chromatography (eluent solvent; hexane:ethyl acetate=1:1). The obtained solid was washed with hexane to prepare 0.840 g (yield 51%) of a target compound.



1H-NMR (CDCl3, ppm) δ 7.36-7.40 (1H, m), 7.53-7.64 (3H, m), 7.84-7.97 (1H, m), 7.92-7.94 (2H, m), 8.04-8.07 (1H, m), 8.08-8.13 (1H, m), 8.20 (2H, s), 8.68-8.72 (1H, m).


Example 4
Preparation of 2-fluoro-3-(4-fluoro-N-methylbenzamide)-N-(2-iodo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)phenyl)benzamide (Compound No. 7-1733)



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<4-1>


Preparation of 2-iodo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)aniline



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To 1200 mL of ethanol was added 200 g (0.600 mol) of 4-(heptafluoropropan-2-yl)-2-(trifluoromethyl)aniline which was obtained in 1-1 of example 1, and 63.2 g (0.630 mol) of concentrated sulfuric acid and 155 g (0.660 mol) of N-iodosuccinimide were added thereto under ice-cooling, followed by stirring at room temperature for 1 hour and 30 minutes and at 40° C. for 4 hours. To the reaction solution was added a 4 M aqueous sodium hydroxide solution to neutralize the reaction solution, and then ethyl acetate was added thereto to extract the organic phase. The organic phase was washed with saturated brine, and dried over anhydrous magnesium sulfate, and then the solvent was evaporated under reduced pressure. The obtained residue was purified by silica gel column chromatography (eluent solvent; hexane:ethyl acetate=10:1) to prepare 216 g (yield 80%) of a target compound.



1H-NMR (CDCl3, ppm) δ 5.04 (2H, broad-s), 7.64 (1H, s), 7.99 (1H, s).


<4-2>


Preparation of 2-chloro-N-(2-iodo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-3-nitrobenzamide



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According to the method of 3-2 of Example 3, a target compound was prepared from 2-iodo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)aniline and 2-chloro-3-nitrobenzoyl chloride.



1H-NMR (CDCl3, ppm) δ 7.60 (1H, t, J=7.8 Hz), 7.76 (1H, s), 7.94 (1H, dd, J=1.5, 7.8 Hz), 7.97 (1H, s), 8.03 (1H, dd, J=1.5, 7.8 Hz), 8.39 (1H, s).


<4-3>


Preparation of 2-fluoro-N-(2-iodo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-3-nitrobenzamide



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According to the method of 1-4 of Example 1, a target compound was prepared from 2-chloro-N-(2-iodo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-3-nitrobenzamide.



1H-NMR (CDCl3, ppm) δ 7.51-7.55 (1H, m), 7.97 (1H, s), 8.23 (1H, d, J=12.2 Hz), 8.28-8.32 (1H, m), 8.37 (1H, s), 8.44-8.48 (1H, m).


<4-4>


Preparation of 3-amino-2-fluoro-N-(2-iodo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)phenyl)benzamide



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According to the method of 1-5 of Example 1, a target compound was prepared from 2-fluoro-N-(2-iodo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-3-nitrobenzamide.



1H-NMR (CDCl3, ppm) δ 3.92 (2H, broad-s), 7.02-7.04 (1H, m), 7.11 (1H, t, J=7.8 Hz), 7.47-7.52 (1H, m), 7.94 (1H, s), 8.30-8.35 (2H, m).


<4-5>


Preparation of 2-fluoro-N-(2-iodo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-3-(methylamino)benzamide



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According to the method of 1-6 of Example 1, a target compound was prepared from 3-amino-2-fluoro-N-(2-iodo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)phenyl)benzamide.



1H-NMR (CDCl3, ppm) δ 2.95 (3H, s), 4.15 (1H, broad-s), 6.90 (1H, t, J=8.2 Hz), 7.19 (1H, t, J=7.8 Hz), 7.40 (1H, t, J=7.8 Hz), 7.92 (1H, s), 8.30 (1H, s), 8.34 (1H, s).


<4-6>


Preparation of 2-fluoro-3-(4-fluoro-N-methylbenzamide)-N-(2-iodo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)phenyl)benzamide (Compound No. 7-1733)



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According to the method of 1-7 of Example 1, a target compound was prepared from 2-fluoro-N-(2-iodo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-3-(methylamino)benzamide and 4-fluorobenzoyl chloride.



1H-NMR (CDCl3, ppm) δ 3.50 (3H, s), 6.91 (2H, s), 6.93-7.35 (3H, m), 7.46 (1H, t, J=7.0 Hz), 7.93 (1H, s), 8.01-8.10 (1H, m), 8.13 (1H, broad-s), 8.34 (1H, s).


Example 5
Preparation of 2-fluoro-3-(3-fluoro-N-methylbenzamide)-N-(2-iodo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)phenyl)benzamide (Compound No. 7-1732)



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According to the method of 1-7 of Example 1, a target compound was prepared from 2-fluoro-N-(2-iodo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)phenyl)-3-(methylamino)benzamide and 3-fluorobenzoyl chloride.



1H-NMR (CDCl3, ppm) δ 3.50 (3H, s), 6.91 (2H, s), 7.00-7.18 (4H, m), 7.27-7.31 (1H, m), 7.45-7.48 (1H, m), 7.93 (1H, s), 8.01-8.03 (1H, m), 8.12 (1H, broad-s), 8.34 (1H, s).


Example 6
Preparation of 2-fluoro-3-(4-fluorobenzamide)-N-(2-iodo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)phenyl)benzamide (Compound No. 6-1733)



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According to the method of 1-7 of Example 1, a target compound was prepared from 3-amino-2-fluoro-N-(2-iodo-4-(heptafluoropropan-2-yl)-6-(trifluoromethyl)phenyl)benzamide and 4-fluorobenzoyl chloride.



1H-NMR (CDCl3, ppm) δ 7.19-7.25 (2H, m), 7.35 (1H, t, J=7.8 Hz), 7.87-7.97 (4H, m), 8.08 (1H, s), 8.25 (1H, d, J=12.0 Hz), 8.37 (1H, s), 8.65 (1H, t, J=8.0 Hz).


Now, the representative examples of the formulations according to the invention will be shown, although the invention is not limited thereto. “Parts” in Formulation Examples indicates “parts by weight”.


Formulation Example 1 (Emulsion)

10 parts of Compound No. 7-1574 or 7-1733, 6 parts of Sol Pol 355S (surfactant available from Toho Chemical Industry Co.), and 84 parts of Solvesso 150 (available from ExxonMobil Chemical Co.) were homogeneously mixed with stirring to obtain as emulsion the composition for exterminating animal parasites.


Formulation Example 2 (Ointment)

1 part of Compound No. 7-1574 or 7-1733, 50 parts of white beeswax, and 49 parts of white petrolatum were thoroughly mixed to obtain as ointment the composition for exterminating animal parasites.


Formulation Example 3 (Tablets)

2 parts of Compound No. 7-1574 or 7-1733, 10 parts of vegetable oil (olive oil), 3 parts of crystalline cellulose, 20 parts of white carbon, and 65 parts of kaolin were thoroughly mixed and then compressed to obtain as tablets the composition for exterminating animal parasites.


Formulation Example 4 (Injectable)

10 parts of Compound No. 7-1574 or 7-1733, 10 parts of propylene glycol for food additives, 80 parts of vegetable oil (corn oil) were mixed to obtain as injectable the composition for exterminating animal parasites.


Formulation Example 5 (Solution)

5 parts of Compound No. 7-1574 or 7-1733, 20 parts of surfactant, and 75 parts of ion-exchanged water were thoroughly mixed to obtain as solution the composition for exterminating animal parasites.


Next, the utility of the composition of the invention as a parasiticide will be concretely explained in the following Test Examples, although the invention is not limited thereto.


Test Example 1

Insecticidal Test for Ctenocephalides Felis


0.5 ml of a solution of acetone, the active ingredient, prepared to the prescribed concentration was added dropwise to a glass tube with a flat bottom (internal diameter 2.6 cm, bottom area: 5.3 cm2, height: 12 cm), and the solvent was evaporated at room temperature to form a dry film of the agent on the bottom surface. About 10 adults of Ctenocephalides Felis per glass tube were added, and the adults were contact-exposed to the test compound. After 24 hours of the exposure, the conditions of the adults were examined and classified into “alive” and “dead (including a moribund condition)” to determine the death rate (in triplicate). The results are shown in Table A4.


As the comparative compounds, the following Compounds (A), (B), and (C) disclosed in WO2009/080203, and fipronil were used.




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TABLE A4







active ingredient
concentration
death rate



(compound number)
(μg/ml)
(%)




















7-1574
0.1
100.0



7-1733
0.1
100.0



7-1732
0.1
76.7



6-1733
0.1
70.0



7-1104
0.1
73.3



compound (A)
1.0
0.0



compound (B)
1.0
3.2



compound (C)
1.0
0.0



fipronil
0.1
92.1



only acetone

4.7










The amide derivatives of Compound No. 7-1574 and 7-1104 were found to be effective even in the examination after 12 hours of the exposure. In addition, they showed immediate effect as compared with the fipronil.


Test Example 2

Insecticidal Test for Haemaphyxalis longicornis


1 ml of a solution of acetone, the active ingredient, prepared to the prescribed concentration was added dropwise to filter paper inside a petri dish with a diameter of 9 cm, and the acetone was evaporated at room temperature. About 100 larvae of Haemaphyxalis longicornis per dish were added to the filter paper. The dish was covered by a polyethylene sheet, sealed with a rubber band, and placed in a dark place at a temperature of 25° C. and a relative humidity of 100% to expose the larvae to the test substance. After 24 hours of the exposure, the conditions of the larvae were examined and classified into “alive” and “dead (including a moribund condition)”. As a result, the amide derivatives according to the invention were found to be effective in killing Haemaphyxalis longicornis.


Test Example 3

Insecticidal Test for Ctenocephalides felis


0.96 ml of a solution of acetone, the active ingredient, prepared to the prescribed concentration was added dropwise to a glass tube with a flat bottom (internal diameter: 3.6 cm, height: 12 cm), and the solvent was evaporated at room temperature to form a dry film of the agent on the bottom surface. About 10 adults of Ctenocephalides felis per glass tube were added, and they were contact-exposed to the test compound. After 24 hours of the exposure, the conditions of the adults were examined and classified into “alive” and “dead (including a moribund condition)” to determine the death rate was determined (in triplicate). The results are shown in Table A5.


As the comparative compounds, the following Compounds (D) and (E) disclosed in WO2009/080203, and fipronil were used.




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TABLE A5







active ingredient
concentration
death rate



(compound number)
(μg/ml)
(%)




















7-1574
0.03
72.0




0.1
98.9



7-1733
0.03
21.1




0.1
91.6



componud (D)
0.3
22.0




1
61.4



compound (E)
1
0.0



fipronil
0.03
70.0




0.1
100.0



only acetone

1.4










Test Example 4

Insecticidal Test for Rhipicephalus sanguineus


0.5 ml of a solution of acetone, the active ingredient, prepared to the prescribed dose was added dropwise into a glass petri dish with a diameter of 10 cm, and the acetone was evaporated at room temperature. About 10 adults of Rhipicephalus sanguineus per dish were added, and the dish was covered by another glass petri dish that was treated with the active ingredient in the same manner described above. After 18 hour exposure to the test substance, the adults were transferred into a glass petri dish that was not treated with the active ingredient. After 48 hours of the exposure, the conditions of the adults were examined and classified into “alive” and “dead (including a moribund condition)” to determine the death rate (in single). The results are shown in Table A6.


As the comparative compounds, said Compounds (B), (C), and (D), and the following Compound (F) disclosed in WO2009/080203, and fipronil were used.




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TABLE A6







active ingredient
concentration
death rate



(compound number)
(mg/m2)
(%)




















7-1574
0.0431
10.0




0.0861
100.0




0.172
100.0



7-1733
0.0431
0.0




0.0861
80.0




0.172
100.0



compound (B)
0.673
0.0




2.69
20.0




10.8
50.0



compound (C)
0.673
0.0




2.69
11.1




10.8
10.0



compound (D)
0.673
0.0




2.69
10.0




10.8
50.0



compound (F)
0.673
0.0




2.69
0.0




10.8
0.0



fipronil
0.0431
0.0




0.172
45.5




0.673
100.0










As the composition for exterminating animal parasites according to the invention has excellent activity for exterminating animal parasites, the composition has wide industrial applicability.


The foregoing description of the exemplary embodiments of the present invention has been provided for the purposes of illustration and description. It is not intended to be exhaustive or to limit the invention to the precise forms disclosed. Obviously, many modifications and variations will be apparent to practitioners skilled in the art. The exemplary embodiments were chosen and described in order to best explain the principles of the invention and its practical applications, thereby enabling others skilled in the art to understand the invention for various embodiments and with the various modifications as are suited to the particular use contemplated. It is intended that the scope of the invention be defined by the following claims and their equivalents.


All publications, patent applications, and technical standards mentioned in this specification are herein incorporated by reference to the same extent as if each individual publication, patent application, or technical standard was specifically and individually indicated to be incorporated by reference.

Claims
  • 1. An amide derivative represented by the following Formula (1):
  • 2. The amide derivative according to claim 1, which is represented by the following Formula (7):
  • 3. The amide derivative according to claim 2, which is represented by the following Formula (8):
  • 4. The amide derivative according to claim 3, wherein in Formula (8), Y3 represents a C3-C4 perfluoroalkyl group.
  • 5. The amide derivative according to claim 4, wherein in Formula (8), Y1 and Y5 each independently represent a chlorine atom, a bromine atom, an iodine atom, a trifluoromethoxy group, a trifluoromethyl group, or a pentafluoroethyl group, and Y2 and Y4 represent hydrogen atoms.
  • 6. The amide derivative according to claim 5, wherein in Formula (8), X1 and X2 each independently represent a hydrogen atom or a fluorine atom, and X3 and X4 represent hydrogen atoms.
  • 7. The amide derivative according to claim 6, wherein in Formula (8), R1 and R2 each independently represent a hydrogen atom or a methyl group.
  • 8. The amide derivative according to claim 7, wherein in Formula (8), Q1 represents a phenyl group or a pyridyl group which may have a substituent selected from a group consisting of a halogen atom, a C1 haloalkyl group, a nitro group, and a cyano group.
  • 9. The amide derivative according to claim 8, wherein in Formula (8), the number of the substituents in Q1 is 1 or 2.
  • 10. The amide derivative according to claim 2, wherein in Formula (7), Y3 represents a C2-C4 perfluoroalkyl group, Y2 and Y4 represent hydrogen atoms, Y1 and Y5 each represent a halogen atom or a C1-C3 haloalkyl group, and either Y1 or Y5 represents a C1-C3 haloalkyl group.
  • 11. The amide derivative according to claim 10, wherein in Formula (7), X1 to X4 each independently represent a hydrogen atom, a halogen atom, or a cyano group.
  • 12. The amide derivative according to claim 1, which is represented by the following Formula (9):
  • 13. The amide derivative according to claim 12, wherein in Formula (9), Y3 represents a C2-C4 perfluoroalkyl group, Y2 and Y4 represent hydrogen atoms, Y1 and Y5 each represent a halogen atom or a C1-C3 haloalkyl group, and either Y1 or Y5 represents a C1-C3 haloalkyl group.
  • 14. The amide derivative according to claim 13, wherein in Formula (9), X1 to X4 each independently represent a hydrogen atom, a halogen atom, or a cyano group.
  • 15. The amide derivative according to claim 1, wherein in Formula (1), K represents a non-metal atom group necessary for forming a cyclic linking group derived from pyridine, pyridine-N-oxide, pyrimidine, pyrazine, pyridazine, triazine, pyrrole, pyrazole, imidazole, oxazole, isoxazole, thiazole, isothiazole, furan, thiophene, oxadiazole, thiodiazole, or triazole, in combination with A and two carbon atoms to which A bonds.
  • 16. The amide derivative according to claim 15, wherein in Formula (1), Y3 represents a C2-C4 perfluoroalkyl group, Y2 and Y4 represent hydrogen atoms, Y1 and Y5 each represent a halogen atom or a C1-C3 haloalkyl group, and either Y or Y5 represents a C1-C3 haloalkyl group.
  • 17. The amide derivative according to claim 16, wherein in Formula (1), K represents a non-metal atom group necessary for forming a cyclic linking group derived from pyridine, pyridine-N-oxide, pyrrole, thiazole, furan, or thiophene, in combination with A and two carbon atoms to which A bonds.
  • 18. A pest control agent comprising at least one amide derivative according to claim 1 as an active ingredient.
  • 19. A pest controlling method comprising applying the pest control agent according to claim 18 to a pest.
  • 20. A composition for controlling a pest comprising as an active ingredient at least one amide derivative represented by the following Formula (A1):
  • 21. The composition according to claim 20, wherein the pest is an animal parasite.
  • 22. The composition according to claim 21, wherein in Formula (A1), Q1 represents a phenyl group or a phenyl group substituted with a single fluorine atom; R1 represents a hydrogen atom or a methyl group; and Y1 and Y5 each independently represent a bromine or iodine atom or a trifluoromethyl group.
  • 23. The composition according to claim 22, wherein the amide derivative represented by Formula (A1) is 2-fluoro-3-(N-methylbenzamide)-N-(2-bromo-6-trifluoromethyl-4-(heptafluoropropan-2-yl)phenyl)benzamide, 2-fluoro-3-(4-fluoro-N-methylbenzamide)-N-(2-iodo-6-trifluoromethyl-4-(heptafluoropropan-2-yl)phenyl)benzamide, 2-fluoro-3-(3-fluoro-N-methylbenzamide)-N-(2-iodo-6-trifluoromethyl-4-(heptafluoropropan-2-yl)phenyl)benzamide, 2-fluoro-3-(4-fluorobenzamide)-N-(2-iodo-6-trifluoromethyl-4-(heptafluoropropan-2-yl)phenyl)benzamide, or 2-fluoro-3-(N-methylbenzamide)-N-(2,6-dibromo-4-(heptafluoropropan-2-yl)phenyl)benzamide.
  • 24. A method for exterminating animal parasites, comprising administering to an animal the composition according to claim 21.
  • 25. The method according to claim 24, wherein the animal parasite is an ectoparasite.
  • 26. The method according to claim 25, wherein the ectoparasite is Siphonaptera pests.
  • 27. The method according to claim 25, wherein the ectoparasite is Acarina pests.
Priority Claims (2)
Number Date Country Kind
2008-208714 Aug 2008 JP national
2010-019747 Jan 2010 JP national
CROSS-REFERENCE TO RELATED APPLICATIONS

This application is a continuation-in-part application of PCT Application PCT/JP2009/061914, filed Jun. 30, 2009, and claims the benefit of U.S. provisional Application No. 61/329,695, filed Apr. 30, 2010, the disclosures of which are incorporated by reference herein. This application also claims priority under 35 USC 119 from Japanese patent Application No. 2008-208714, filed on Aug. 13, 2008 and Japanese patent Application No. 2010-019747, filed on Jan. 29, 2010, the disclosures of which are incorporated by reference herein.

Provisional Applications (1)
Number Date Country
61329695 Apr 2010 US
Divisions (2)
Number Date Country
Parent 13845664 Mar 2013 US
Child 13949866 US
Parent 13016604 Jan 2011 US
Child 13845664 US
Continuations (1)
Number Date Country
Parent 13949866 Jul 2013 US
Child 15698249 US
Continuation in Parts (1)
Number Date Country
Parent PCT/JP2009/061914 Jun 2009 US
Child 13016604 US