Claims
- 1. An (amido)N-substituted bleomycinic acid represented by the following formula or a salt thereof: ##STR26## wherein BM represents a moiety of bleomycin skeleton; X represents (1) an alkyl of 1 to 18 carbon atoms, (2) an aminoalkyl of 1 to 12 carbon atoms, (3) a lower alkyl having as substituent (a) 1 to 3 halogen atoms, (b) 1 or 2 phenyl groups, (c) an indolyl group, or (d) a 5- or 6-membered heterocyclic group containing an oxygen, sulfur or nitrogen atom (among the substituent groups, the phenyl or indolyl group may be further substituted by a halogen atom or a lower alkoxy group), (4) X.sub.1 -(lower)alkyl, [where X.sub.1 is ##STR27## X.sub.2 is a hydrogen atom, a lower alkyl or benzyl, X.sub.3 is (a) a lower alkyl, (b) a phenyl(lower)alkyl, or (c) a mono- or di-(lower)alkylamino(lower)alkyl which may be substituted by a phenyl or halophenyl group, X.sub.4 is (a) a lower alkyl or (b) a phenyl(lower)alkyl], (5) naphthyl, (6) thiazolyl, or (7) an N-phenyl(lower)alkylpiperazinyl.
Priority Claims (1)
Number |
Date |
Country |
Kind |
56-210447 |
Dec 1981 |
JPX |
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Parent Case Info
This is a division of application Ser. No. 451,437, filed Dec. 20, 1982, now U.S. Pat. No. 4,472,304.
Foreign Referenced Citations (1)
Number |
Date |
Country |
2519637 |
Jul 1983 |
FRX |
Divisions (1)
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Number |
Date |
Country |
Parent |
451437 |
Dec 1982 |
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