Claims
- 1. Antiatherosclerotic compounds of the formula:
- 2. The antiatherosclerotic compounds of claim 1 wherein,
R is lower alkyl; R1 is lower alkoxy; R2 and R3 are each hydrogen; Ar is phenyl, indanyl, or phenyl optionally with one or more members selected from the group consisting of halogen, lower alkyl, lower alkoxy, and aryloxy; or pharmaceutically acceptable salts thereof.
- 3. The antiatherosclerotic compound of claim 1 which is Ethyl [[[[(5-Chloro-2-methylphenyl)amino]thioxomethyl]methylamino]oxy] acetate
- 4. The antiatherosclerotic compound of claim 1 which is Ethyl [[[[(4-Chloro-2-methylphenyl)amino]thioxomethyl]methylamino]oxy] acetate.
- 5. The antiatherosclerotic compound of claim 1 which is Ethyl [[[[(2,3-dihydro-1H-inden-5-yl)amino]thioxomethyl]methylamino]oxy] acetate.
- 6. The antiatheroscierotic compound of claim 1 which is Ethyl [[methyl [[(2-(1-methylethyl)phenyl]amino]thioxomethyl]methylamino]oxy] acetate.
- 7. The antiatherosclerotic compound of claim 1 which is Ethyl [[[[(2,5-dimethylphenyl)amino]thioxomethyl]methylamino]oxy] acetate.
- 8. The antiatherosclerotic compound of claim 1 which is Ethyl [[[[(2-methylpropyl)amino]thioxomethyl]methylamino]oxy] acetate.
- 9. The antiatherosclerotic compound of claim 1 which is Ethyl [[[[(4-phenoxyphenyl)amino]thioxomethyl]methylamino]oxy] acetate.
- 10. The antiatherosclerotic compound of claim 1 which is Ethyl [[[[(4-Chloro-2-methylphenyl)amino]thioxomethyl]ethylamino]oxy] acetate.
- 11. The antiatherosclerotic compound of claim 1 which is Ethyl [[[[(5-Chloro-2-methylphenyl)amino]thioxomethyl](1-methylethyl)amino]oxy] acetate
- 12. The antiatherosclerotic compound of claim 1 which is Ethyl [[[[(5-Chloro-2-methylphenyl)amino]thioxomethyl](1-methylpropyl)amino]oxy] acetate
- 13. A pharmaceutical composition comprising an antiatherosclerotic compound of the formula:
- 14. A method of treating atherosclerosis in a mammal in need thereof, which comprises administering to said mammal an anti-atherosclerotic effective amount of a compound of the formula:
Parent Case Info
[0001] This application claims priority from copending provisional application Ser. No. 60/237,466, filed Oct. 2, 2000, the entire disclosure of which is hereby incorporated by reference.
Provisional Applications (1)
|
Number |
Date |
Country |
|
60237466 |
Oct 2000 |
US |