An implantable chronic 128 channel macro and micro ECoG system with integrated recording, stimulation, and impedance measuring capabilities

Information

  • Research Project
  • 9085458
  • ApplicationId
    9085458
  • Core Project Number
    R43NS093729
  • Full Project Number
    5R43NS093729-02
  • Serial Number
    093729
  • FOA Number
    PA-14-071
  • Sub Project Id
  • Project Start Date
    6/15/2015 - 9 years ago
  • Project End Date
    5/31/2017 - 7 years ago
  • Program Officer Name
    LANGHALS, NICK B
  • Budget Start Date
    6/1/2016 - 8 years ago
  • Budget End Date
    5/31/2017 - 7 years ago
  • Fiscal Year
    2016
  • Support Year
    02
  • Suffix
  • Award Notice Date
    6/15/2016 - 8 years ago

An implantable chronic 128 channel macro and micro ECoG system with integrated recording, stimulation, and impedance measuring capabilities

? DESCRIPTION (provided by applicant): The objective of this proposal is to design, develop, and validate a commercially viable human-use smart 128-channel macro & micro ECoG microsystem with integrated recording, stimulation, and impedance measuring capabilities for epilepsy monitoring. The microsystem comprises of a state-of-art microelectronic signal processing component linked to a macro & micro integrated ECoG grid via a thin, highly flexible, bio- compatible micro-ribbon cable on one end and a single percutaneous flexible-cable (pigtail) on the other end. The custom multiplexing ASIC electronics is capable of 128-channel recordings at 16-bit resolution and has fast settle capability (for stimulation option) and patient safety circuitry. The component is contained on a printed circuit board and is encapsulated with Parylene-C and Silicone. The encapsulated microelectronic component unit is encased in a titanium case and resides subcutaneously between the skin and the skull. The integrated microsystem would have unique snow-flake shape grid design containing alternate rows of macro and micro channels. The phase-I would target a short-term goal of developing, bench testing and validating in adult sheep model the complete implantable ECoG microsystem that can be translated to research and clinical lab in the shortest time frame.

IC Name
NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
  • Activity
    R43
  • Administering IC
    NS
  • Application Type
    5
  • Direct Cost Amount
  • Indirect Cost Amount
  • Total Cost
    349542
  • Sub Project Total Cost
  • ARRA Funded
    False
  • CFDA Code
    853
  • Ed Inst. Type
  • Funding ICs
    NINDS:349542\
  • Funding Mechanism
    SBIR-STTR RPGs
  • Study Section
    ZRG1
  • Study Section Name
    Special Emphasis Panel
  • Organization Name
    BLACKROCK MICROSYSTEMS
  • Organization Department
  • Organization DUNS
    827132015
  • Organization City
    SALT LAKE CITY
  • Organization State
    UT
  • Organization Country
    UNITED STATES
  • Organization Zip Code
    841081229
  • Organization District
    UNITED STATES