Animal Models for the Prevention and Treatment of Hepatitis C

Information

• Research Project
• 8428901

• ApplicationId

  8428901

• Core Project Number

  N01AI000000

• Full Project Number

  N01AI60004-8-0-1

• Serial Number

• FOA Number

• Sub Project Id

• Project Start Date

  4/7/2006 - 18 years ago

• Project End Date

  9/29/2010 - 13 years ago

• Program Officer Name

• Budget Start Date

  -

• Budget End Date

  -

• Fiscal Year

  2012

• Support Year

• Suffix

• Award Notice Date

  -

Organizations

• KMT HEPATECH INC

Chronic infections caused by hepatitis C virus affect hundreds of millions of people worldwide and may lead to life-threatening conditions like cirrhosis and cancer. New safer and more effective therapies are needed to prevent the end stage liver diseases that cause one million hepatitis-related deaths a year. The scid/Alb-uPA mouse carrying a chimeric liver with implanted human cells is the only small animal model of hepatitis C replication. This contract utilizes this animal model to evaluate candidate therapeutic compounds. Antiviral compounds evaluated can include small molecule drugs, antibodies and RNAi.

IC Name

• Activity

  N01

• Administering IC

  AI

• Application Type

• Direct Cost Amount

• Indirect Cost Amount

• Total Cost

  260577

• Sub Project Total Cost

• ARRA Funded

  False

• CFDA Code

  855

• Ed Inst. Type

• Funding ICs

  NIAID:260577\

• Funding Mechanism

  Non SBIR/STTR Contracts

• Study Section

• Study Section Name

• Organization Name

  KMT HEPATECH, INC.

• Organization Department

• Organization DUNS

• Organization City

  EDMONTON

• Organization State

  AB

• Organization Country

  CANADA

• Organization Zip Code

  76G 2E1

• Organization District

  CANADA