DeVries, M.E. et al., “On the edge: the physiological and pathophysiological role of chemokines during inflammatory and immunological responses”, Semin.Immunol. 1999, vol. 11, pp. 95-104. |
Fischer, F.R. et al., “Modulation of experimental autoimmune encephalomyelitis: effect of altered peptide ligand on chemokine and chemokine receptor expression”, J.Neuroimmunol., 2000, vol. 110, pp. 195-208. |
Hesselgesser, J. et al., “Identification and characterization of small molecule functional antagonists of the CCR1 chemokine receptor”, J.Biol.Chem., 1998, vol. 273, pp. 15687-15692. |
Izikson, L. et al., Resistance to experimental autoimmune encephalomyelitis in mice lacking the CC chemokine receptor (CCR)2, J.Exp.Med., 2000, vol. 192, pp. 1075-1080. |
Kennedy,K.J. et al., “Role of chemokines in the regulation of Th1/Th2 and autoimmune encephalomyelitis”, J.Clin.Immunol., 1999, vol. 19, pp. 273-279. |
Liang, M. et al., “Identification and characterization of a potent, selective, and orally active antagonist of the CC chemokine receptor-1”, J.Biol.Chem., 2000, vol. 275, pp. 19000-19008. |
Liang,M., et al., “Species selectivity of a small molecule antagonist for the CCR1 chemokine receptor”, Eur.J.Pharmacol., 2000, vol. 389, pp. 41-49. |
Ng, H.P. et al., “Discovery of novel non-peptide CCR1 receptor antagonists”, J.Med.Chem, 1999, vol. 42, pp. 4680-4694. |
Plater-Zyberk, C. et al., “Effect of a CC chemokine receptor antagonist on collagen induced arthritis in DBA/1mice”, Immunol.Lett., 1997, vol. 57, pp. 117-120. |
Rottman,J.B. et al., “Leukocyte recruitment during onset of experimental allergic encephalomyelitis is CCR1 dependent”, Eur.J.Immunol., 2000, vol. 30, pp. 2372237-7. |