Claims
- 1. A compound of the formula (I): ##STR29## or a pharmaceutically acceptable salt thereof, wherein R.sup.1 and R.sup.2 are the same or different and each is phenyl which is unsubstituted or substituted by at least one group selected from C.sub.1 -C.sub.4 alkyl and halo, X is ##STR30## X being attached to a carbon atom of A, A is ##STR31## n is from 1 to 3, m is 1 or 2,
- p is 1,
- q is 1 ##STR32## wherein R.sup.4 and R.sup.5 are taken together to form a --Y--(CH.sub.2).sub.s --Z-- group wherein Y and Z are independently --O-- or --CH.sub.2 -- and s is 1, 2 or 3.
- 2. A compound according to claim 1, in which R.sup.1 and R.sup.2 are both unsubstituted phenyl.
- 3. A compound according to 2, in which X is >C(OH)--.
- 4. A compound according to claim 1, in which R.sup.3 is, 2,3-dihydro-benzofuranyl, ##STR33##
- 5. A compound according to claim 4, in which R.sup.3 is 3,4-methylenedioxyphenyl.
- 6. A pharmaceutical composition comprising a compound as claimed in claim 1 and a pharmaceutically acceptable diluent or carrier.
- 7. A method of treating or preventing irritable bowel syndrome, diverticular disease, urinary incontinence, oesophageal achalasia, or chronic obstructive airways disease, comprising administering to a patient an effective amount of a compound according to claim 1.
Priority Claims (1)
Number |
Date |
Country |
Kind |
9000305 |
Jan 1990 |
GBX |
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Parent Case Info
This is a continuation of application Ser. No. 07/877,170, filed on Jun. 29, 1992, now abandoned, which is the national stage of PCT/EP90/02262 filed Dec. 18, 1990.
US Referenced Citations (3)
Non-Patent Literature Citations (1)
Entry |
Kalsner "Trends in autonomic pharmacology" Tayer & Francis pp. 17-19, 28-31 (1985). |
Continuations (1)
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Number |
Date |
Country |
Parent |
877170 |
Jun 1992 |
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