ANTIFUSOGENIC ANTIVIRALS: DESIGN AND TESTING

Information

  • Research Project
  • 2064265
  • ApplicationId
    2064265
  • Core Project Number
    R44AI028126
  • Full Project Number
    5R44AI028126-03
  • Serial Number
    28126
  • FOA Number
  • Sub Project Id
  • Project Start Date
    5/1/1989 - 35 years ago
  • Project End Date
    7/31/1992 - 32 years ago
  • Program Officer Name
  • Budget Start Date
    8/1/1991 - 33 years ago
  • Budget End Date
    7/31/1992 - 32 years ago
  • Fiscal Year
    1991
  • Support Year
    3
  • Suffix
  • Award Notice Date
    8/9/1991 - 33 years ago
Organizations

ANTIFUSOGENIC ANTIVIRALS: DESIGN AND TESTING

DESCRIPTION (adapted from applicant's abstract): This Phase-II proposal describes the synthesis of ten trial ligands to test their ability to prevent membrane fusion of influenza virus by binding to the hemagglutinin (HA) site of the envelope protein. Trial ligands that inhibit exposure of the fusion peptide of HA, and show in vitro inhibition of viral fusion, will be tested for antiviral activity by plaque assay.

IC Name
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
  • Activity
    R44
  • Administering IC
    AI
  • Application Type
    5
  • Direct Cost Amount
  • Indirect Cost Amount
  • Total Cost
  • Sub Project Total Cost
  • ARRA Funded
  • CFDA Code
    856
  • Ed Inst. Type
  • Funding ICs
  • Funding Mechanism
  • Study Section
    PSF
  • Study Section Name
    Physiological Sciences Study Section
  • Organization Name
    SERES LABORATORIES, INC.
  • Organization Department
  • Organization DUNS
  • Organization City
    SANTA ROSA
  • Organization State
    CA
  • Organization Country
    UNITED STATES
  • Organization Zip Code
    954032062
  • Organization District
    UNITED STATES