Claims
- 1. A pharmaceutical composition useful as an antihypertensive comprising an active amount of a compound selected from the class consisting of 2-[4-(tetrahydro-2-furoyl)-piperazino]-4-amino-6,7-dimethoxyquinazoline and 2-[4(tetrahydropyran-2-carbonyl)piperazinyl]-4-amino-6,7-dimethoxyquinazoline and pharmaceutically acceptable acid addition salts thereof and a pharmaceutically acceptacle carrier.
- 2. The composition of claim 1 wherein the compound is 2-[4(tetrahydro-2-furoyl)-piperazino]-4-amino-6,7-dimethoxyquinazoline hydrochloride.
- 3. The composition of claim 1 wherein the compound is 2-[4(tetrahydropyran-2-carbonyl)piperazinyl]-4-amino-6,7-dimethoxyquinazoline hydrochloride.
- 4. The composition of claim 2 wherein said carrier comprises an aqueous vehicle.
- 5. A method of treating hypertension in a mammal comprising administering to a mammal so afflicted, a therapeutically effective amount of a compound selected from the class consisting of 2-[4(tetrahydro-2-furoyl)-piperazino]-4-amino-6,7-dimethoxyquinazoline and 2-[4(tetrahydropyran-2-carbonyl)piperazinyl]-4-amino-6,7-dimethoxyquinazoline and pharmaceutically acceptable acid addition salts thereof.
- 6. The method of claim 5 wherein said compound is 2-[4(tetrahydro-2-furoyl)-piperazino]-4-amino-6,7-dimethoxy-quinazoline hydrochloride.
- 7. The method of claim 5 wherein said compound is 2-[4(tetrahydropyran-2-carbonyl)piperazinyl]-4-amino-6,7-dimethoxyquinazoline hydrochloride.
Parent Case Info
This is a division of application Ser. No. 621,980, filed Oct. 14, 1975 U.S. Pat. No. 4,026,894.
US Referenced Citations (2)
Number |
Name |
Date |
Kind |
3511836 |
Hess |
May 1970 |
|
3920636 |
Takahashi et al. |
Nov 1975 |
|
Divisions (1)
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Number |
Date |
Country |
Parent |
621980 |
Oct 1975 |
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