Claims
- 1. A method of treating inflammatory disorders in a mammal which comprises injecting said mammal with an effective anti-inflammatory amount of an anti-inflammatory agent set out below
- X.sub.1 =X.sub.2 =H or Acyl or X.sub.1 --X.sub.2 =--CH.sub.2 --;
- R.sub.1 =acyl;
- R.sub.2 =OCH.sub.3.
- 2. A method of treating according to claim 1 wherein the method of treatment consists of injecting intraperitoneally into the footpad of a mouse or rat a pharmaceutical amount of the anti-inflammatory agent in claim 1.
- 3. The method of claim 1 wherein the anti-inflammatory agent is (-)-2,3-di-demethylcolchicine.
- 4. The method of claim 1 wherein the anti-inflammatory agent is (-)-2,3-di-acetoxydidemethylcolchicine.
- 5. The method of claim 1 wherein the anti-inflammatory agent is (-)-cornigerine.
- 6. The method of claim 1 wherein the anti-inflammatory agent is (-)-2,3-di-butyroxy-N-butyryl-deacetylcolchicine.
- 7. The method of claim 1 wherein the anti-inflammatory agent is (-)-2,3-di-demethylN-butyryl-deacetylcolchicine.
- 8. The method of claim 1 wherein the anti-inflammatory agent is (.+-.)-2,3-di-demethylcolchicine.
Parent Case Info
This is a continuation-in-part application of pending Ser. No. 705,709 filed Feb. 26, 1985, abandoned.
US Referenced Citations (2)
Number |
Name |
Date |
Kind |
2820029 |
Muller et al. |
Jan 1958 |
|
3997506 |
Dugat |
Dec 1976 |
|
Non-Patent Literature Citations (1)
Entry |
Capraro and Brossi, "Tropolonic Colchicum Alkaloids", The Alkaloids, vol. 23, Academic Press, 1984, pp. 35-36. |
Continuation in Parts (1)
|
Number |
Date |
Country |
Parent |
705709 |
Feb 1985 |
|