Claims
- 1. A method of treating a neoplasm in a mammal in need thereof, which comprises providing to said mammal an effective amount of a combination comprising CCI-779 and an antineoplastic alkylating agent.
- 2. The method according to claim 1, wherein the neoplasm is renal cancer.
- 3. The method according to claim 1, wherein the neoplasm is soft tissue sarcoma.
- 4. The method according to claim 1, wherein the neoplasm is breast cancer.
- 5. The method according to claim 1, wherein the neoplasm is a neuroendocrine tumor of the lung.
- 6. The method according to claim 1, wherein the neoplasm is cervical cancer.
- 7. The method according to claim 1, wherein the neoplasm is uterine cancer.
- 8. The method according to claim 1, wherein the neoplasm is a head and neck cancer.
- 9. The method according to claim 1, wherein the neoplasm is glioma.
- 10. The method according to claim 1, wherein the neoplasm is non-small cell lung cancer.
- 11. The method according to claim 1, wherein the neoplasm is prostate cancer.
- 12. The method according to claim 1, wherein the neoplasm is pancreatic cancer.
- 13. The method according to claim 1, wherein the neoplasm is lymphoma.
- 14. The method according to claim 1, wherein the neoplasm is melanoma.
- 15. The method according to claim 1, wherein the neoplasm is small cell lung cancer.
- 16. The method according to claim 1, wherein the neoplasm is ovarian cancer.
- 17. The method according to claim 1, wherein the neoplasm is colon cancer.
- 18. The method according to claim 1, wherein the neoplasm is esophageal cancer.
- 19. The method according to claim 1, wherein the neoplasm is gastric cancer.
- 20. The method according to claim 1, wherein the neoplasm is leukemia.
- 21. The method according to claim 1, wherein the neoplasm is colorectal cancer.
- 22. The method according to claim 1, wherein the neoplasm is unknown primary cancer.
- 23. The method according to claim 1, wherein the antineoplastic alkylating agent is selected from the group consisting of meclorethamine, cyclophosphamide, ifosfamide, melphalan, chlorambucil, thiotepa, mitomycin, busulfan, lomustine, carmustine, procarbazine, temozolomide, cisplatin, and carboplatin.
- 24. A method of treating a neoplasm in a mammal in need thereof, which comprises providing to said mammal an effective amount of a combination comprising CCI-779 and an antineoplastic alkylating agent, wherein either CCI-779, the alkylating agent, or both are provided in subtherapeutically effective amounts.
- 25. The method according to claim 24 in which CCI-779 is provided in a subtherapeutically effective amount.
- 26. The method according to claim 24 in which the alkylating agent is provided in a subtherapeutically effective amount.
- 27. The method according to claim 24 in which both CCI-779 and the alkylating agent are provided in subtherapeutically effective amounts.
- 28. An antineoplastic combination which comprises an effective amount of CCI-779 and an antineoplastic alkylating agent.
Parent Case Info
[0001] This application claims priority from copending provisional application Serial No. 60/295,236, filed Jun. 1, 2001, the entire disclosure of which is hereby incorporated by reference.
Provisional Applications (1)
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Number |
Date |
Country |
|
60295236 |
Jun 2001 |
US |