Claims
- 1. An antiphlogistic, analgesic, antipyretic and the platelet aggregation inhibiting pharmaceutical composition comprising a correspondingly effective amount of a compound of the formula ##STR6## wherein each of R.sub.1, R.sub.3 and R.sub.4 represents hydrogen, lower alkyl, lower alkoxy, or halogen up to and including atomic number 35, and R.sub.2 represents hydrogen, lower alkyl, lower alkoxy, halogen up to and including atomic number 35, or trifluoromethyl, with exclusion of the simultaneous definition of the substituents R.sub.1, R.sub.2 and R.sub.3 as hydrogen, or a pharmaceutically acceptable salt thereof, together with a pharmaceutical carrier therefor.
- 2. The method of producing an antiphlogistic effect in a mammal which comprises administering to said mammal antiphlogistically an effective amount of a composition according to claim 1.
- 3. The method of producing an analgesic effect in a mammal which comprises administering to said mammal an analgesically effective amount of a composition according to claim 1.
- 4. A composition according to claim 1, wherein in the effective compound R.sub.4 has the meaning given in claim 1, each of R.sub.1 and R.sub.3 represents hydrogen, methyl, or halogen up to and including atomic number 35 and R.sub.2 represents hydrogen, methyl, halogen up to and including atomic number 35, or trifluoromethyl, with the exclusion of the simultaneous definition of R.sub.1, R.sub.2 and R.sub.3 as hydrogen, or salts thereof with pharmaceutically acceptable inorganic bases.
- 5. A composition according to claim 1, wherein in the effective compound R.sub.4 has the meaning given in claim 1, R.sub.1 represents methyl or chlorine and each of R.sub.2 and R.sub.3 represents hydrogen, methyl or chlorine, or salts thereof with pharmaceutically acceptable inorganic bases.
- 6. A composition according to claim 1, wherein the effective compound is the [o-(2,6-dichloroanilino)-phenyl]-acetohydroxamic acid.
- 7. A composition according to claim 1, wherein the effective compound is the [o-(2,6-dichloro-m-toluidino)-phenyl]-acetohydroxamic acid.
- 8. A composition according to claim 1, wherein the effective compound is the [o-(3-chloro-o-toluidino)-phenyl]-acetohydroxamic acid.
- 9. A composition according to claim 1, wherein the effective compound is the [o-(6-chloro-o-toluidino)-phenyl]-acetohydroxamic acid.
- 10. A composition according to claim 1, wherein the effective compound is the [o-(2,6-xylidino)-phenyl]-acetohydroxamic acid.
Priority Claims (2)
Number |
Date |
Country |
Kind |
13415/70 |
Sep 1970 |
CH |
|
10580/71 |
Jul 1971 |
CH |
|
CROSS REFERENCE
This application is a continuation of application Ser. No. 467,366, filed May 6, 1974, which, in turn, is a continuation in part of Ser. No. 177,088 filed Sept. 1, 1971 (both of which are now abandoned).
US Referenced Citations (2)
Number |
Name |
Date |
Kind |
3673243 |
Yamamoto et al. |
Jun 1972 |
|
3692819 |
Carney et al. |
Sep 1972 |
|
Continuations (1)
|
Number |
Date |
Country |
Parent |
467366 |
May 1974 |
|
Continuation in Parts (1)
|
Number |
Date |
Country |
Parent |
177088 |
Sep 1971 |
|