Claims
- 1. A compound of Formula I ##STR35## and the pharmaceutically acceptable acid addition salts thereof wherein R.sup.1 is selected from formyl, carbalkoxy, nitro, phenyl, and ##STR36## wherein R.sup.7 is lower alkyl; R.sup.2 is selected from hydrogen, halogen, lower alkyl, or lower alkoxy;
- Z is selected from ##STR37## R.sup.3 and R.sup.4 are independently selected from lower alkyl.
- 2. A compound of claim 1 wherein R.sup.2 is hydrogen.
- 3. A compound of claim 1 wherein R.sup.2 is lower alkyl or alkoxy.
- 4. The compound of claim 1, 4,4-dimethyl-1-[4-[4-(3-phenyl-2-pyridinyl)-1-piperazinyl]butyl]-2,6-piperidinedione.
- 5. The compound of claim 1, methyl 2-[4-[4-(4,4-dimethyl-2,6-dioxo-1-piperidinyl)butyl]-1-piperazinyl]pyridine-3-carboxylate.
- 6. A pharmaceutical composition in dosage unit form suitable for systemic administration to a mammalian host comprising a pharmaceutical carrier and from about 1-500 mg of a compound claimed in claim 1.
- 7. The method for ameliorating an undesirable psychotic state in a mammal comprising administration to said mammal an effective antipsychotic amount of a compound claimed in claim 1.
CROSS REFERENCE TO RELATED APPLICATIONS
This application is a division of application U.S. Ser. No. 691,952, filed Jan. 16, 1985 and now U.S. Pat. No. 4,619,930.
US Referenced Citations (2)
Number |
Name |
Date |
Kind |
4361565 |
Temple, Jr. et al. |
Nov 1982 |
|
4524206 |
New et al. |
Jun 1985 |
|