Baba et al., Chem AB, 106:149011u (1987). |
Balzarini et al, "Differential Antiherpesvirus and Antiretrovirus Effects of the (S) and (R) Enantiomers of Acyclic Nucleoside Phosphonates," Antimicro AG & Chemo 37(2):332-338 (1993). |
Barnard et al, "Selective inhibition of cytomegaloviruses by 9-(3'-ethylphosphono-1'-hydroxymethyl-1'propyloxy-methyl)guanine," Antiviral Res 22:77-89 (1993). |
Birnbaum et al, "Conformation features of acyclonucleosides: structure of acyclovir, an antiherpes agent," Can J Chem 62:2646-2652 (1984). |
De Clercq, "Broad-Spectrum Anti-DNA Virus and Anti-Retrovirus Activity of Phosphonylmethoxyalkylpurines and -Pyrimidines," Biochem Pharm 42(5):963-972 (1991). |
De Clercq et al, "A novel selective broad-spectrum anti-DNA virus agent," Nature 323:464-467 (1986). |
De Clercq et al., "Antiviral Activity of Aliphatic Nucleoside Analogues: Structure-Function Relationship," J Med Chem 22(5):510-513 (1979). |
Engel, R., "Phosphonates as Analogues of Natural Phosphates," Chem Rev 77:349-367 (1977). |
Holy et al., "3'-0-Phosphonylmethyl-9-(S)-(2,3-dihydroxypropyl)adenine novel type of biologically active nucleotide analogue," Nuc Acids Res 14:277-278 (1984). |
Holy et al., "Phosphonylmethyl Ethers of Nucleosides and Their Acyclic Analogues," J Am Chem Soc 4:51-71 (1989). |
Keller et al, "Enzymatic Phosphorylation of Acyclic Nucleoside Analogs and Correlations with Antiherpetic Activities," Biochem Pharm 30(22):3071-3077 (1981). |
Kim et al, "Acyclic Purine Phosphonate Analogues as Antivral Agents. Synthesis and Structure--Activity Relationships," J Med Chem 33:1207-1213 (1990). |
Kritsyn et al, "Nonglycoside Analogs of Nucleotides. Report 6*. Mono-And Triphosphates of w-Hydroxyalkyl Derivatives of Nucleic Bases," Institute of Molecular Biology 8:1846-1850 (1975). |
Pauwels et al, "Phosphonylmethoxyethyl Purine Derivatives, A New Class of Anti-Human Immunodeficiency Virus Agents," Antimicro AG & Chemo 32(7) 1025-1030 (1988). |
Prisbe et al., "Synthesis and Antiherpes Virus Activity of Phosphate and Phosphonate Derivatives of 9-�1,3-Dihydroxy-2-propoxy)methyl!guanine," J Med Chem 29:671-675 (1986). |
Sidwell et al., "Effect of Phosphonic Acid Analogs of Acyclovir and Ganciclovir on In Vitro Cytomegalovirus Infections," Nucls & Nuclt 8:833-836 (1989). |
Starrett et al., "Synthesis, Oral Bioavailability Determination, and in Vitro Evaluation of Prodrugs of the Antiviral Agent 9-�2-(Phosphonomethoxy)eth!adenine (PMEA)," J Med Chem 37:1857-1864 (1994). |
Steitweiser Jr., Introduction to Organic Chemistry, 2 ed., pp. 132-134 (1981). |
Balzarini, Antimicorbial Agents and Chemotherapy, vol. 37, p. 332, Feb. 1998. |
Yu, J. Med. Chem. vol. 35, 2858, Aug. 1992. |
Sidwell, Nucleoside and Nucleotides vol. 8, 833, 1989. |
Yang, Antiviral Res. Suppliment 1, #162, p. 131, Apr. 1991. |