The present technology is generally related to a surgical apparatus for minimally invasive surgical procedures including articulating features.
Minimally invasive surgical procedures involve the deployment of instrumentation through small openings in a wall of body tissue. This type of surgery is highly advantageous because trauma to the patient is substantially reduced, which also reduces recovery time, costs, and the risk of post-operative complications. For convenience, as hereinafter used the term “endoscopic” shall refer generally to all types of minimally invasive surgical procedures, including laparoscopic procedures.
Endoscopic instruments can include articulation capabilities; however, it can be difficult to effectively operate and/or control the articulating portion of the instrument during the surgical procedure from outside the body. For example, providing and/or maintaining an adequate amount of force in or around the area of articulation can be difficult, e.g., because the tissue can provide resistance against the articulation which in some instances can limit the range of articulation, cause the articulating means to fail or slip during articulation, and/or cause at least partial reversal of the articulation over time, specifically after a surgeon's hand is removed from the instrument.
There remains a need for methods and devices which allow minimally invasive surgical procedures to be performed with enhanced stability of an articulated configuration of the surgical instrument thereby maximizing the range of articulation, reducing or preventing failure or slipping of the articulating means, and/or limiting the range of reversal of the articulation. Efficiency of the surgical procedure can also be improved by freeing the surgeon's hands for other surgical related activities.
The present disclosure describes a surgical apparatus for use in minimally invasive surgical procedures including at least one articulating feature. The surgical apparatus includes a non-endoscopic portion and an endoscopic portion. The endoscopic portion includes at least first and second segments connected by at least one angled rotary interface joint. The first segment includes a first proximal end portion operatively connected to the non-endoscopic portion and a first distal end portion having a first beveled gear and a second beveled gear positioned therein. The second beveled gear is positioned between the first beveled gear and an angled gear affixed on a second proximal end portion of the second segment.
In some embodiments, the first beveled gear includes a first set of alternating teeth and slots configured to mechanically interact with a second set of alternating teeth and slots of the second beveled gear, and the second set of alternating teeth and slots are also configured to mechanically interact with a third set of alternating teeth and slots of the angled gear. The angled gear is a non-beveled gear. In some embodiments, the angled gear is an angled spur gear.
In some embodiments, the first segment includes a first outer wall defining a first lumen along a first longitudinal axis defined between the first proximal end portion and the first distal end portion of the first segment. The first and second beveled gears are maintained within the first lumen.
In some embodiments, the first beveled gear faces distally along the first longitudinal axis and includes a rotary driver extending proximally therefrom along the first longitudinal axis to the non-endoscopic portion. In some embodiments, the second beveled gear is positioned on a post positioned distal to the first beveled gear, the post extending generally perpendicular to the first longitudinal axis and affixed on an inner surface of the first outer wall.
The first segment and/or the outer wall of the first segment can further include an angled circumferential channel defined therethrough. The channel is configured to receive at least a portion of the angled gear.
In some embodiments, the angled gear includes a set of alternating teeth and slots extending radially outward from a side of the angled gear. In some embodiments, the set of alternating teeth and slots extending radially outward from a side of the angled gear are received within the angled circumferential channel.
In some embodiments, the first distal end portion of the first segment further includes a first angled edge spaced distally from the angled circumferential channel. The first angled edge configured to form a first half of an angled interface.
In some embodiments, the second segment includes a second outer wall defining a second lumen along a second longitudinal axis defined between the second proximal end portion and a second distal end portion. The second segment is configured to rotate about the angled rotary interface joint relative to the first segment. In some embodiments, the second longitudinal axis and the first longitudinal axis are collinear when the endoscopic portion is straight. In some embodiments, the second longitudinal axis of the second segment is about 90° relative to the first longitudinal axis of the first segment.
In some embodiments, the second proximal end portion of the second segment further includes a second angled edge. The second angled edge being spaced distally from the angled gear by a gap defined by a sidewall having a second length. The second angled edge configured to form a second half of an angled interface. The first and second angled edges in combination forming an angled interface.
In addition to the first and second segments, the endoscopic portion of the surgical apparatus also includes a distal operating portion operatively coupled to a second distal end portion of the second segment. The distal operating portion can include a surgical unit selected from the group consisting of a surgical stapler unit, surgical retractor unit, surgical sealer unit, surgical ablation unit, or clip applier unit.
In some embodiments, the surgical apparatus described herein includes a non-endoscopic portion and an endoscopic portion having at least first and second segments connected by at least one angled rotary interface joint including a first beveled gear, a second beveled gear, and an angled non-beveled gear, wherein the first beveled gear drives the angled non-beveled gear via the second beveled gear.
Methods of using the surgical apparatus described herein in minimally invasive surgical procedures are also provided.
Various embodiments are described herein by way of example in conjunction with the following figures.
The surgical apparatus described herein includes features to provide for rotary articulation of a distal endoscopic portion thereof. The articulation features may be employed on a variety of endoscopic instruments such as clip appliers, staplers, graspers, tissue retractors, tissue sealers, shears, dissectors, manipulators, pushers, and the like.
Referring to
In some embodiments, as shown in
Referring to
As can be seen from
This articulation of the second segment 105 with the distal operating portion presents many advantages. For example, it allows the endoscopic portion 101 to be inserted through a cannula, yet also permits the instrument, after insertion, to be configured to angled shapes. This permits the surgeon to gain access to body tissue which is otherwise difficult to reach.
The first distal end portion 103b of the first segment 103 also includes an angled circumferential channel 109 defined completely through the first outer wall 20. The angled circumferential channel 109 defines a second geometric plane P2 creating a first inner angle ia1 relative to the first longitudinal axis L1. In some embodiments, the first and second planes P1, P2 are parallel to each other. In some embodiments, the first inner and outer angles ia1, oa1 are supplementary angles.
As depicted, the angled circumferential channel 109 extends around a majority, i.e., greater than about 50% of the outer perimeter of the first segment 103 along the second plane P2. In some embodiments, the angled circumferential channel 109 extends between about 55% to about 95% of the outer perimeter of the first segment 103 along the second plane P2. In some embodiments, the angled circumferential channel 109 extends between about 60% to about 80% of the outer perimeter of the first segment 103 along the second plane P2.
As further depicted specifically in
The second beveled gear 27 includes a second set of alternating teeth 28a and slots 28b configured to mechanically interact with both the first set of alternating teeth 24a and slots 24b of the first beveled gear 23 and a third set of alternating teeth 31a and slots 31b of the angled gear 30. The second beveled gear 27 is maintained on a post 29 fixed to an inner surface of the first outer wall 20 and extending therefrom in a direction generally perpendicular to the first longitudinal axis L1. In some embodiments, the first and second beveled gears generally face each other perpendicularly.
As further shown in
In some embodiments, the third geometric plane P3 defined by the angled gear 33 is parallel to or aligned with the second geometric plane P2 of the channel 109. In some embodiments, the third geometric plane P3 defined by the angled gear 33 is not parallel or not aligned perfectly the second geometric plane P2 of the channel 109.
The angled gear 33 is spaced from a second angled edge 32 by a spacer wall 35 defining a gap 36 therebetween. The length lg of the gap 36 between the second angled edge 32 and the backside of the angled gear 33 being generally equal a thickness of first angled edge 22 and/or the distance di between the first angled edge 22 and the angled circumferential channel 109 of the first segment 103, such that the first and second segments 103, 105 remain tightly coupled to each other when the angled gear 33 is located, at least partially if not predominantly, within the angled circumferential channel 109.
The second angled edge 32 defines a fourth geometric plane P4 creating a second inner angle ia2 relative to the second longitudinal axis L2. In some embodiments, the third and fourth planes P3, P4 are parallel to each other. In some embodiments, the second inner and outer angles ia2, oa2 are supplementary angles. In some embodiments, the first and fourth planes P1, P4 are parallel to or aligned with each other and the second and third planes P2, P3 are parallel to or aligned with each other.
As further depicted in
As further depicted in
In some embodiments, a pushrod 50 extends longitudinally through the joint 104 and connects an actuator 113 in the handle portion 110 with the distal operating portion 107. The pushrod 50 can operate by reciprocating motion or by rotation. The pushrod can be super elastic in order to permit flexing at the joint while providing for actuation of the distal operating portion. Various types of metal alloys are known in the art, for example shape memory alloys, may be used to fabricate the push rod.
In some embodiments, the angled gear 33 is centered on the second proximal end portion 105a of the second segment 105. In some embodiments, the angled gear 33 is offset from a center of the second proximal end portion 105a of the second segment 105.
When the first and second segments 103, 105 are coupled as depicted in
In some embodiments, as shown in
The combination and/or configuration of the three gears as described herein provides a more stable and efficient articulating joint configured to withstand a greater amount of resistance inside the body. For example, by fixing the non-beveled gear (e.g., a spur gear) at an angle, and particularly and obtuse angle, relative to the second beveled gear (as opposed to perpendicular to a gear), the second and third different sets of alternating teeth and slots can interact more efficiently thereby reducing skipping or failure of the joint during articulation. In another example, by spacing the first beveled gear (e.g., the drive gear) from the angled gear via the second beveled gear, any resistance is spread over the entirety of the gear configuration (as opposed to a single location) thereby reducing localized strain and again reducing skipping or failure of the joint during articulation. Also, by the first segment includes a channel and the angled gear including radially outward extending teeth and grooves configured to be received within the channel, the overall size of the angled gear can be maximized while remaining positioned within the first lumen of the first segment thereby enhancing the overall strength of the articulating joint, the joint is less likely to get jammed or slip gears, as compared to joints wherein only two angled gears directly interact with each other, and more particularly wherein a beveled gear interacts directly with a crown gear. The enhanced stability can increase efficiency of the surgical apparatus and can also decrease the likelihood of reversal of the articulation upon removal of the surgeon's hand from the apparatus, especially as compared to articulating joints wherein only two angled gears directly interact with each other, and more particularly wherein a beveled gear interacts directly with an angled crown gear.
Referring now to
Annular seals 52a and 52b prevent the passage of gas or other fluids through the apparatus. Seals 52a and 52b are preferably fabricated from a synthetic polymeric material and may be lubricated with a biocompatible lubricant grease, such as a silicone or a solid lubricant, or they may be self-lubricating by having a low coefficient of friction or by containing a lubricant within the structure of the seal material.
Rotary actuator 113 includes a disk-shaped member mounted in slot 111d in the body portion and having axles 113a rotatably mounted within slots 111a in the body portion and aligned in parallel with the axis of the instrument. The upper portion of the disk-shaped member of the rotary actuator 113 extends beyond the surface of the body portion 111 to allow actuation by a user's finger. The lower portion of the disk-shaped member extends through slot 108a to contact the rotary driver 40. The periphery of the disk portion includes gear teeth 113b which engage the corresponding notches 44 of the rotary driver. Thus, mechanical rotation of rotary actuator 113 by the surgeon causes rotation of the rotary drive tube 140, which, in turn, causes rotating articulation of the second segment 105 around angled joint 104.
Optionally, a click-stop feature 160 may be included which comprises a plunger 161 slidably disposed within slot 163 and resiliently biased by spring 162 into engagement with corresponding slits (not shown) arrayed on the proximal surface of disk-shaped rotary actuator 113. The distal tip of plunger 161 is rounded to permit disengagement when a sufficient turning force has been applied to rotary actuator 113. The biasing force of the spring 162 is adapted for releasable engagement of the click-stop mechanism 160 by selecting a suitable spring 162 such that the position of the rotary actuator 113 (and second segment 105) is stabilized against free spinning and unintended movement of the actuator 113. Movement is easily accomplished when the surgeon actuates the rotary actuator 113, and the click-stop feature 160 provides audible as well as tactile indication when a certain position has been reached.
The proximal end of outer tube 108 includes a flange 108b which is fixedly mounted to a slot 111b in the body portion.
Push rod 50 is operatively connected to drive cylinder 140, which is disposed within bore 112 of the body portions. In some embodiments, the drive cylinder 140 is pneumatically powered and has an internal movable piston (not shown) which drives the push rod 50 with a reciprocating motion for actuating the distal operating portion 107. Optionally, a rotary motion can be employed, in conjunction with a linear cam or barrel cam. Suitable pneumatic drive cylinder devices are known to those with skill in the art and are commercially available.
The pneumatic drive cylinder 140 is controlled by switching unit 141 which includes a valve mechanism. Plunger 143 is mounted to the switching unit 141 and operates a valve for controlling the flow of compressed gas to drive pneumatic cylinder 140. Plunger 143 is resiliently biased by spring 142 to a closed-valve position. Trigger mount 144 is pivotally mounted to body portion 111 by means of pivot pins 145.
Trigger 130 is an elongated member having a projection 132 adapted for rotatable engagement with a corresponding slot in trigger mount 144 such that trigger 130 may be pivoted with respect to trigger mount 144.
The cam member 144 includes a bottom surface 146 which is angled with respect to the longitudinal axis of the body portion 111. Likewise, the trigger 130 includes a surface 132 angled with respect to the lengthwise extension of the trigger 130. Surfaces 132 and 146 are in slidable contact to form angled rotary interface 131. Pivoting trigger 130 around an axis of rotation defined by projection 132 will move trigger between differently angled positions with respect to body portion 111.
Pressing of the trigger 130 causes trigger mount 144 to pivot around pins 145 and contact the plunger 143. Further pressing of the trigger moves the plunger 143 against the biasing force of spring 142 to open the valve in drive switching unit 141. This permits the flow of compressed gas to drive the pneumatic drive cylinder 140.
The compressed gas may be provided by a compressed gas storage bottle 150 mounted in the interior of handle grip 120. The handle grip 120 is an elongated generally cylindrical member 122 which may be fabricated as two mating halves 122a and 122b which join to form an enclosure for mounting the gas bottle 150. A flexible tube 151 extends from the gas bottle 150 through axial bore in the rotatable coupling 152 to switching unit 141 and carries compressed gas thereto. Tube 151 possesses a rotating seal 151a which permits tube portions 151b and 151c to rotate relative to each other without the tube 151 pinching closed.
Body portion 111 possesses a proximal wall 115 oriented at an angle with respect to the longitudinal axis of the body portion. Handle grip 120 possesses a distal wall 123 which is oriented at an angle with respect to the longitudinal axis of the handle grip. Walls 115 and 123 face each other in sliding contact to form an angled rotary interface 121 similar in operational features to rotary interface 104. That is, handle grip 120 may be rotated relative to body portion 111 to move from a position in linear alignment with the body portion 111, as shown in
To permit rotation around rotary interface 121 a rotatable coupling 152 is provided. Coupling 152 is disposed through centrally located apertures 123a and 115a in the distal and proximal walls 123 and 115, respectively, and possesses circumferential flanges 152a and 152b which abut the inner surfaces of the facing walls 115 and 123 in the vicinity of apertures 115a and 123a. Thus, wall 123 of the handle grip 100 and wall 115 of the body portion are held in slidable contact and are rotatable with respect to each other around an axis defined by the rotatable coupling 152. Rotatable coupling 152 also possess a central bore for passage of tube 151 therethrough.
Referring now to
Handle grip 220 and body portion 210 are pivotally connected at rotary interface 221 by means of a coupling 252, such as coupling 152 described above.
Endoscopic portion 201 is similar in operation to endoscopic portion 101 and is similarly actuated by means of rotary actuator 213.
An alternative hydraulically operated actuation mechanism 240 is employed, which comprises first and second cylindrical hydraulic chambers 241 and 242 containing a hydraulic fluid such as water, oil or other suitable liquid, and connected by means of two fluid carrying tubes 243 and 244.
A movable piston (not shown) is located in the interior of each hydraulic chamber. The piston in the first hydraulic chamber 241 is mechanically linked to trigger 230 by means of rod 245. The pistol in the second hydraulic chamber 242 is mechanically linked to drive rod 205 for actuating the distal operating portion of the apparatus. When the apparatus 200 is actuated by pressing trigger 230, the trigger 230 pivots (clockwise, as shown) around pivot pin 231 and moves rod 245 out of first chamber 241, thereby forcing hydraulic fluid through tube 243 and into the distal end of the second chamber 242. The piston in the second chamber 242 is forced to move proximally, thereby pulling the drive rod 205 proximally and actuating the distal operating portion. Fluid exits the second hydraulic chamber 242 via line 244 and enters the first hydraulic chamber 241. Alternative configurations of the hydraulic tubes may be employed to move the drive rod distally instead of proximally. Also, hydraulic chamber 242 may alternatively incorporate a hydraulically driven rotor to turn drive rod 205 rather than move it linearly. Optionally, a spring 246 may be employed to bias the trigger 230 back to its initial position.
Turning now to
Housing 320 is operatively connected to a first proximal end portion 103b of the first segment 103. Housing 320 is connected to handle assembly 330 which includes a fixed handle 350 and a movable handle 340. Fixed handle 350 is integrally associated with housing 320 and handle 340 is movable relative to fixed handle 350. Movable handle 340 can be connected to a drive assembly (not shown) which, together, mechanically cooperate to impart movement of the jaw members 102a, 102b from an open position wherein the jaw members 102a, 102b are disposed in spaced relation relative to one another, to a clamping or closed position wherein the jaw members 102a, 102b cooperate to grasp tissue therebetween.
Rotating assembly 380 may also be integrally associated with the housing 320 and is configured to rotate the end effector 102 via rotating wheel 382 approximately 180 degrees in either direction about a longitudinal axis “A-A” defined through endoscopic portion 101.
As further depicted in
Cable 310 can be divided internally into one or more cable wires or leads which each transmit electrosurgical energy through their respective feed paths through the forceps 300. One set of cable wires or leads can extend from cable 310 and connect electrically the joy-stick-like toggle switch 400 with the end effector 102 for sealing tissue. It is envisioned that actuation of the switch 400 permits the user to selectively activate the jaw members 102a, 102b to seal tissue.
It is further envisioned that another set of cable wires or leads can extend from cable 310 and connect trigger assembly 70 to a motor (not shown) located inside housing 320. The motor connected to a proximal end portion of a rotary driver. Actuation of the trigger assembly 370 would permit the user to selectively activate rotation of the rotary driver via the motor (as opposed to the manual actuator 113) causing the second segment 105 to articulate or rotate around the angled rotary interface joint 104 via the first and second beveled gears and the angled gear as described herein. As can be appreciated, automation of the rotatory driver can accelerate and/or simplify the articulation process.
Referring now to
To position the distal operating portion 107 the surgeon turns actuator 113 to angle the second segment 105. The distal operating portion 107 may then be actuated by pressing trigger 130.
Prior to removal, the surgeon can turn actuator 113 again until the second segment 105, including distal operating portion 107, is returned to a collinear configuration with first segment 103 and cannula assembly 501a.
In some embodiments, the apparatus described herein may be used in a method for surgically operating on body tissue in the interior of a body cavity. Such a method may include: inserting an endoscopic portion of a surgical apparatus described herein through a cannula assembly into the body cavity; positioning a distal operating portion of the apparatus at an operating site; and actuating said distal operating portion. In such embodiments, the surgical apparatus includes a non-endoscopic portion and an endoscopic portion. The endoscopic portion ht least a first segment, a second segment, and the distal operation portion. The first segment including a first proximal end portion operatively connected to the non-endoscopic portion and a first distal end portion connected to a second proximal end portion of the second segment by at least one angled rotary interface joint, the first distal end portion including a first beveled gear and a second beveled gear, the second beveled gear positioned between the first beveled gear and an angled gear affixed on the second proximal end portion of the second segment, and the distal operating portion connected to a second distal end portion of the second segment.
It will be understood that various modifications may be made to the embodiments disclosed herein. Therefore, the above description should not be construed as limiting, but merely as exemplifications of preferred embodiments. Those skilled in the art will envision other modifications within the scope and spirit of the claims appended hereto.
Number | Name | Date | Kind |
---|---|---|---|
4202352 | Osborn | May 1980 | A |
5057494 | Sheffield | Oct 1991 | A |
5321113 | Cooper et al. | Jun 1994 | A |
5330502 | Hassler et al. | Jul 1994 | A |
5358496 | Ortiz et al. | Oct 1994 | A |
5431323 | Smith et al. | Jul 1995 | A |
5575799 | Bolanos | Nov 1996 | A |
5725536 | Oberlin et al. | Mar 1998 | A |
6003517 | Sheffield | Dec 1999 | A |
6007550 | Wang et al. | Dec 1999 | A |
6086586 | Hooven | Jul 2000 | A |
6436107 | Wang et al. | Aug 2002 | B1 |
6533784 | Truckai et al. | Mar 2003 | B2 |
6656177 | Truckai et al. | Dec 2003 | B2 |
6786382 | Hoffman | Sep 2004 | B1 |
6802843 | Truckai et al. | Oct 2004 | B2 |
6835336 | Watt | Dec 2004 | B2 |
6913579 | Truckai et al. | Jul 2005 | B2 |
7111769 | Wales et al. | Sep 2006 | B2 |
7398707 | Morley et al. | Jul 2008 | B2 |
7721934 | Shelton, IV et al. | May 2010 | B2 |
7726537 | Olson et al. | Jun 2010 | B2 |
7780054 | Wales | Aug 2010 | B2 |
7947000 | Vargas et al. | May 2011 | B2 |
7955315 | Feinberg et al. | Jun 2011 | B2 |
8335359 | Fidrich et al. | Dec 2012 | B2 |
8337515 | Viola et al. | Dec 2012 | B2 |
8397971 | Yates et al. | Mar 2013 | B2 |
8579176 | Smith et al. | Nov 2013 | B2 |
8706184 | Mohr et al. | Apr 2014 | B2 |
8827934 | Chopra et al. | Sep 2014 | B2 |
8915940 | Steege et al. | Dec 2014 | B2 |
8961499 | Paik et al. | Feb 2015 | B2 |
8968187 | Kleyman et al. | Mar 2015 | B2 |
9289225 | Shelton, IV et al. | Mar 2016 | B2 |
9375268 | Long | Jun 2016 | B2 |
9470297 | Aranyi et al. | Oct 2016 | B2 |
9480492 | Aranyi et al. | Nov 2016 | B2 |
9801630 | Harris et al. | Oct 2017 | B2 |
9918659 | Chopra et al. | Mar 2018 | B2 |
10004498 | Morgan et al. | Jun 2018 | B2 |
10004558 | Long et al. | Jun 2018 | B2 |
10085746 | Fischvogt | Oct 2018 | B2 |
10172973 | Vendely et al. | Jan 2019 | B2 |
10194897 | Cedro et al. | Feb 2019 | B2 |
10206686 | Swayze et al. | Feb 2019 | B2 |
10292758 | Boudreaux et al. | May 2019 | B2 |
10349938 | Widenhouse et al. | Jul 2019 | B2 |
10373719 | Soper et al. | Aug 2019 | B2 |
10376178 | Chopra | Aug 2019 | B2 |
10390899 | Malkowski et al. | Aug 2019 | B2 |
10405753 | Sorger | Sep 2019 | B2 |
10478162 | Barbagli et al. | Nov 2019 | B2 |
10480926 | Froggatt et al. | Nov 2019 | B2 |
10524866 | Srinivasan et al. | Jan 2020 | B2 |
10555788 | Panescu et al. | Feb 2020 | B2 |
10569071 | Harris et al. | Feb 2020 | B2 |
10603106 | Weide et al. | Mar 2020 | B2 |
10610306 | Chopra | Apr 2020 | B2 |
10638953 | Duindam et al. | May 2020 | B2 |
10639114 | Schuh et al. | May 2020 | B2 |
10674970 | Averbuch et al. | Jun 2020 | B2 |
10682070 | Duindam | Jun 2020 | B2 |
10702137 | Deyanov | Jul 2020 | B2 |
10706543 | Donhowe et al. | Jul 2020 | B2 |
10709506 | Coste-Maniere et al. | Jul 2020 | B2 |
10716637 | Kowshik et al. | Jul 2020 | B2 |
10729886 | Fenech et al. | Aug 2020 | B2 |
10743751 | Landey et al. | Aug 2020 | B2 |
10772485 | Schlesinger et al. | Sep 2020 | B2 |
10779803 | Prisco et al. | Sep 2020 | B2 |
10792022 | Keast et al. | Oct 2020 | B2 |
10792464 | Romo et al. | Oct 2020 | B2 |
10796432 | Mintz et al. | Oct 2020 | B2 |
10823627 | Sanborn et al. | Nov 2020 | B2 |
10827913 | Ummalaneni et al. | Nov 2020 | B2 |
10835153 | Rafii-Tari et al. | Nov 2020 | B2 |
10856855 | Gordon | Dec 2020 | B2 |
10881385 | Fenech | Jan 2021 | B2 |
10885630 | Li et al. | Jan 2021 | B2 |
20020147462 | Mair et al. | Oct 2002 | A1 |
20030013972 | Makin | Jan 2003 | A1 |
20030032948 | Dubrowskij | Feb 2003 | A1 |
20040120981 | Nathan | Jun 2004 | A1 |
20040260334 | Braun | Dec 2004 | A1 |
20050165276 | Belson et al. | Jul 2005 | A1 |
20060235457 | Belson | Oct 2006 | A1 |
20070135803 | Belson | Jun 2007 | A1 |
20080045938 | Weide et al. | Feb 2008 | A1 |
20130096385 | Fenech et al. | Apr 2013 | A1 |
20130303945 | Blumenkranz et al. | Nov 2013 | A1 |
20140035798 | Kawada et al. | Feb 2014 | A1 |
20140052018 | Hawkins | Feb 2014 | A1 |
20140235943 | Paris et al. | Aug 2014 | A1 |
20150148690 | Chopra et al. | May 2015 | A1 |
20150265368 | Chopra et al. | Sep 2015 | A1 |
20160001038 | Romo et al. | Jan 2016 | A1 |
20160067450 | Kowshik | Mar 2016 | A1 |
20160157939 | Larkin et al. | Jun 2016 | A1 |
20160183841 | Duindam et al. | Jun 2016 | A1 |
20160192860 | Allenby et al. | Jul 2016 | A1 |
20160287344 | Donhowe et al. | Oct 2016 | A1 |
20160331358 | Gordon | Nov 2016 | A1 |
20160374676 | Flanagan et al. | Dec 2016 | A1 |
20170020628 | Averbuch | Jan 2017 | A1 |
20170112571 | Thiel et al. | Apr 2017 | A1 |
20170112576 | Coste-Maniere et al. | Apr 2017 | A1 |
20170112588 | Bissing et al. | Apr 2017 | A1 |
20170209071 | Zhao et al. | Jul 2017 | A1 |
20170224338 | Sung | Aug 2017 | A1 |
20170238795 | Blumenkranz et al. | Aug 2017 | A1 |
20170258309 | Deyanov | Sep 2017 | A1 |
20170265952 | Donhowe et al. | Sep 2017 | A1 |
20170274189 | Smith et al. | Sep 2017 | A1 |
20170311844 | Zhao et al. | Nov 2017 | A1 |
20170319165 | Averbuch | Nov 2017 | A1 |
20180001058 | Schlesinger | Jan 2018 | A1 |
20180064904 | Vargas et al. | Mar 2018 | A1 |
20180078318 | Barbagli et al. | Mar 2018 | A1 |
20180144092 | Flitsch et al. | May 2018 | A1 |
20180153621 | Duindam et al. | Jun 2018 | A1 |
20180214138 | Prisco et al. | Aug 2018 | A9 |
20180221039 | Shah | Aug 2018 | A1 |
20180235709 | Donhowe et al. | Aug 2018 | A1 |
20180240237 | Donhowe et al. | Aug 2018 | A1 |
20180256262 | Duindam et al. | Sep 2018 | A1 |
20180263706 | Averbuch | Sep 2018 | A1 |
20180279852 | Rafii-Tari et al. | Oct 2018 | A1 |
20180325419 | Zhao et al. | Nov 2018 | A1 |
20190000559 | Berman et al. | Jan 2019 | A1 |
20190000560 | Berman et al. | Jan 2019 | A1 |
20190008413 | Duindam et al. | Jan 2019 | A1 |
20190038365 | Soper et al. | Feb 2019 | A1 |
20190065209 | Mishra et al. | Feb 2019 | A1 |
20190076143 | Smith | Mar 2019 | A1 |
20190110839 | Rafii-Tari et al. | Apr 2019 | A1 |
20190175062 | Rafii-Tari et al. | Jun 2019 | A1 |
20190175799 | Hsu et al. | Jun 2019 | A1 |
20190183318 | Froggatt et al. | Jun 2019 | A1 |
20190183585 | Rafii-Tari et al. | Jun 2019 | A1 |
20190183587 | Rafii-Tari et al. | Jun 2019 | A1 |
20190192143 | Shelton, IV et al. | Jun 2019 | A1 |
20190192234 | Gadda et al. | Jun 2019 | A1 |
20190200984 | Shelton, IV et al. | Jul 2019 | A1 |
20190209016 | Herzlinger et al. | Jul 2019 | A1 |
20190209043 | Zhao et al. | Jul 2019 | A1 |
20190216548 | Ummalaneni | Jul 2019 | A1 |
20190223693 | Vargas | Jul 2019 | A1 |
20190231449 | Diolaiti et al. | Aug 2019 | A1 |
20190239723 | Duindam et al. | Aug 2019 | A1 |
20190239724 | Averbuch et al. | Aug 2019 | A1 |
20190239831 | Chopra | Aug 2019 | A1 |
20190246876 | Schaning | Aug 2019 | A1 |
20190250050 | Sanborn et al. | Aug 2019 | A1 |
20190254649 | Walters et al. | Aug 2019 | A1 |
20190269470 | Barbagli et al. | Sep 2019 | A1 |
20190269818 | Dhanaraj et al. | Sep 2019 | A1 |
20190269819 | Dhanaraj et al. | Sep 2019 | A1 |
20190269885 | Bailey et al. | Sep 2019 | A1 |
20190272634 | Li et al. | Sep 2019 | A1 |
20190290375 | Dearden et al. | Sep 2019 | A1 |
20190298160 | Ummalaneni et al. | Oct 2019 | A1 |
20190298451 | Wong et al. | Oct 2019 | A1 |
20190320878 | Duindam et al. | Oct 2019 | A1 |
20190320937 | Duindam et al. | Oct 2019 | A1 |
20190328213 | Landey et al. | Oct 2019 | A1 |
20190336238 | Yu et al. | Nov 2019 | A1 |
20190343424 | Blumenkranz et al. | Nov 2019 | A1 |
20190350659 | Wang et al. | Nov 2019 | A1 |
20190365199 | Zhao et al. | Dec 2019 | A1 |
20190365479 | Rafii-Tari | Dec 2019 | A1 |
20190365486 | Srinivasan et al. | Dec 2019 | A1 |
20190380787 | Ye et al. | Dec 2019 | A1 |
20200000319 | Saadat et al. | Jan 2020 | A1 |
20200000526 | Zhao | Jan 2020 | A1 |
20200008655 | Schlesinger et al. | Jan 2020 | A1 |
20200008827 | Dearden et al. | Jan 2020 | A1 |
20200022767 | Hill et al. | Jan 2020 | A1 |
20200029948 | Wong et al. | Jan 2020 | A1 |
20200030044 | Wang et al. | Jan 2020 | A1 |
20200030461 | Sorger | Jan 2020 | A1 |
20200030575 | Bogusky et al. | Jan 2020 | A1 |
20200038750 | Kojima | Feb 2020 | A1 |
20200043207 | Lo et al. | Feb 2020 | A1 |
20200046431 | Soper et al. | Feb 2020 | A1 |
20200046436 | Tzeisler et al. | Feb 2020 | A1 |
20200054399 | Duindam et al. | Feb 2020 | A1 |
20200054408 | Schuh et al. | Feb 2020 | A1 |
20200060771 | Lo et al. | Feb 2020 | A1 |
20200069192 | Sanborn et al. | Mar 2020 | A1 |
20200069384 | Fenech et al. | Mar 2020 | A1 |
20200077870 | Dicarlo et al. | Mar 2020 | A1 |
20200077991 | Gordon et al. | Mar 2020 | A1 |
20200078023 | Cedro et al. | Mar 2020 | A1 |
20200078095 | Chopra et al. | Mar 2020 | A1 |
20200078103 | Duindam et al. | Mar 2020 | A1 |
20200085514 | Blumenkranz | Mar 2020 | A1 |
20200100776 | Blumenkranz et al. | Apr 2020 | A1 |
20200107894 | Wallace et al. | Apr 2020 | A1 |
20200109124 | Pomper et al. | Apr 2020 | A1 |
20200121170 | Gordon et al. | Apr 2020 | A1 |
20200129045 | Prisco | Apr 2020 | A1 |
20200129239 | Bianchi et al. | Apr 2020 | A1 |
20200138514 | Blumenkranz et al. | May 2020 | A1 |
20200138515 | Wong | May 2020 | A1 |
20200142013 | Wong | May 2020 | A1 |
20200146757 | Fenech et al. | May 2020 | A1 |
20200155116 | Donhowe et al. | May 2020 | A1 |
20200155232 | Wong | May 2020 | A1 |
20200170623 | Averbuch | Jun 2020 | A1 |
20200170720 | Ummalaneni | Jun 2020 | A1 |
20200179058 | Barbagli et al. | Jun 2020 | A1 |
20200188021 | Wong et al. | Jun 2020 | A1 |
20200188038 | Donhowe et al. | Jun 2020 | A1 |
20200205903 | Srinivasan et al. | Jul 2020 | A1 |
20200205904 | Chopra | Jul 2020 | A1 |
20200214664 | Zhao et al. | Jul 2020 | A1 |
20200222666 | Chan et al. | Jul 2020 | A1 |
20200229679 | Zhao et al. | Jul 2020 | A1 |
20200242767 | Zhao et al. | Jul 2020 | A1 |
20200261175 | Fenech | Aug 2020 | A1 |
20200268240 | Blumenkranz et al. | Aug 2020 | A1 |
20200275860 | Duindam | Sep 2020 | A1 |
20200289023 | Duindam et al. | Sep 2020 | A1 |
20200297442 | Adebar et al. | Sep 2020 | A1 |
20200305983 | Yampolsky et al. | Oct 2020 | A1 |
20200315554 | Averbuch et al. | Oct 2020 | A1 |
20200330795 | Sawant et al. | Oct 2020 | A1 |
20200345436 | Kowshik et al. | Nov 2020 | A1 |
20200352427 | Deyanov | Nov 2020 | A1 |
20200352675 | Averbuch | Nov 2020 | A1 |
20200364865 | Donhowe et al. | Nov 2020 | A1 |
20200367726 | Landey et al. | Nov 2020 | A1 |
20200383750 | Kemp et al. | Dec 2020 | A1 |
20200391010 | Fenech et al. | Dec 2020 | A1 |
20200406002 | Romo et al. | Dec 2020 | A1 |
20210000524 | Barry et al. | Jan 2021 | A1 |
Number | Date | Country |
---|---|---|
0013237 | Jul 2003 | BR |
0116004 | Jun 2004 | BR |
0307259 | Dec 2004 | BR |
0412298 | Sep 2006 | BR |
112018003862 | Oct 2018 | BR |
1644519 | Dec 2008 | CZ |
486540 | Sep 2016 | CZ |
2709512 | Aug 2017 | CZ |
2884879 | Jan 2020 | CZ |
1644519 | Dec 2008 | EP |
2141497 | Jan 2010 | EP |
3326551 | May 2018 | EP |
3367915 | Jul 2019 | EP |
3413830 | Sep 2019 | EP |
3576598 | Dec 2019 | EP |
3478161 | Feb 2020 | EP |
3641686 | Apr 2020 | EP |
3644885 | May 2020 | EP |
3644886 | May 2020 | EP |
3749239 | Dec 2020 | EP |
03005028 | Jan 2004 | MX |
03000137 | Sep 2004 | MX |
03006874 | Sep 2004 | MX |
225663 | Jan 2005 | MX |
226292 | Feb 2005 | MX |
03010507 | Jul 2005 | MX |
05011725 | May 2006 | MX |
06011286 | Mar 2007 | MX |
246862 | Jun 2007 | MX |
2007006441 | Aug 2007 | MX |
265247 | Mar 2009 | MX |
284569 | Mar 2011 | MX |
Entry |
---|
PCT Search Report and Written Opinion issued in PCT/US2021/052080 dated Dec. 22, 2021, 12 pages. |
Number | Date | Country | |
---|---|---|---|
20220087665 A1 | Mar 2022 | US |