Claims
- 1. A compound having the structure:
- 2. The compound of claim 1 wherein R1 is hydrogen or alkyl.
- 3. The compound of claim 2 wherein R1 is methyl.
- 4. The compound of claim 1 wherein R2 is hydrogen, halogen, alkoxy, alkyl or substituted alkyl
- 5. The compound of claim 1 wherein R2 is hydrogen.
- 6. The compound of claim 1 where R3 is hydrogen, halogen, hydroxy, alkoxy or alkyl.
- 7. The compound of claim 1 where R3 is heterocycle.
- 8. The compound of claim 7 where R3 is morpholinyl.
- 9. The compound of claim 1 wherein R4 is hydrogen or alkoxy.
- 10. The compound of claim 1 wherein R5 is hydrogen.
- 11. The compound of claim 1 wherein R4 taken together with R5, and further taken together with the respective carbon atom to which these groups are attached, form an unsubstituted fused phenyl group.
- 12. The compound of claim 1 wherein R2, R4 and R5 are hydrogen.
- 13. The compound of claim 12 wherein R1 is methyl and R3 is hydroxy.
- 14. A pharmaceutical composition comprising a compound of claim 1 and a pharmaceutically acceptable carrier.
- 15. A method for treating an arthritic disorder, comprising administering an effective amount of a pharmaceutical composition of claim 14 to an animal in need thereof.
- 16. A method for treating a disease associated with altered mitochondrial function comprising administering an effective amount of a pharmaceutical composition of claim 14 to an animal in need thereof.
CROSS-REFERENCE TO RELATED APPLICATION
[0001] This application is a continuation of U.S. patent application Ser. No. 10/085,119, filed Feb. 27, 2002, now allowed; and claims the benefit of U.S. Provisional Application No. 60/272,368 filed Feb. 27, 2001, which applications are incorporated herein by reference in their entireties.
Provisional Applications (1)
|
Number |
Date |
Country |
|
60272368 |
Feb 2001 |
US |
Continuations (1)
|
Number |
Date |
Country |
Parent |
10085119 |
Feb 2002 |
US |
Child |
10386154 |
Mar 2003 |
US |