Claims
- 1. A method for treating viral infections comprising extending the elimination half-life of d4T metabolite in a mammal by administering an effective amount of a compound of Formula I:
- 2. The method of claim 1, wherein the aryl group is selected from the group consisting of phenyl, naphthyl, and anthryl.
- 3. The method of claim 1, wherein the aryl group is phenyl.
- 4. The method of claim 1, wherein the electron-withdrawing group is a halo.
- 5. The method of claim 1, wherein Ri is para-bromophenyl.
- 6. The method of claim 1, wherein R2 is an α-amino acid or ester thereof.
- 7. The method of claim 1, wherein R2 is —NHCH(CH3)COOCH3.
- 8. The method of claim 1, wherein Ri is para-bromophenyl and R2 is —NHCH(CH3)COOCH3.
- 9. The method of claim 1, wherein the viral infection is HIV.
- 10. A method for treating HIV comprising extending the elimination half-life of d4T in a mammal by administering an effective amount of a compound of Formula IV:
- 11. The method of claim 10, wherein R2 is an α-amino acid or ester.
- 12. The method of claim 10, wherein R2 is —NHCH(CH3)COOCH3.
- 13. The method of claim 10, wherein the viral infection is HIV.
Parent Case Info
[0001] This application claims priority from provisional application serial No. 60/299,885, filed Jun. 21, 2001 and provisional application serial no. 60/244,263, filed Oct. 30, 2000, both of which are incorporated herein by reference.
Provisional Applications (2)
|
Number |
Date |
Country |
|
60299885 |
Jun 2001 |
US |
|
60244263 |
Oct 2000 |
US |