ASSAY METHODS TO DETECT CYTOMEGALOVIRUS

Information

  • Research Project
  • 3645652
  • ApplicationId
    3645652
  • Core Project Number
    N43HB067014
  • Full Project Number
    N43HB067014-000
  • Serial Number
    67014
  • FOA Number
  • Sub Project Id
  • Project Start Date
    10/7/1985 - 38 years ago
  • Project End Date
    -
  • Program Officer Name
  • Budget Start Date
    10/7/1985 - 38 years ago
  • Budget End Date
    4/7/1986 - 38 years ago
  • Fiscal Year
    1986
  • Support Year
  • Suffix
  • Award Notice Date
    -
Organizations

ASSAY METHODS TO DETECT CYTOMEGALOVIRUS

The contractor's objective is to detect blood units infectious for cytomegalovirus (CMV) by using the relatively new technique of in situ hybridization with cloned, biotinylated segments of CMV DNA. The signal will then be identified using a non-radioactive enzyme probe. The system will be optimized using CMV-infected human fibroblasts. Further testing using blood "spiked" with infected cells will be performed to determine the effect of blood/blood cells on signal detection. The final step in developing the assay will be to test actual specimens and compare to results obtained by standard culture techniques.

IC Name
DIVISION OF BLOOD DISEASES AND RESOURCES
  • Activity
    N43
  • Administering IC
    HB
  • Application Type
    1
  • Direct Cost Amount
  • Indirect Cost Amount
  • Total Cost
  • Sub Project Total Cost
  • ARRA Funded
  • CFDA Code
    839
  • Ed Inst. Type
  • Funding ICs
  • Funding Mechanism
  • Study Section
  • Study Section Name
  • Organization Name
    ENZO BIOCHEM, INC.
  • Organization Department
  • Organization DUNS
  • Organization City
    NEW YORK
  • Organization State
    NY
  • Organization Country
    UNITED STATES
  • Organization Zip Code
    10013
  • Organization District
    UNITED STATES