The inventions described below relate the field of atrial ablation.
Atrial fibrillation is a form of arrhythmia, or irregular heartbeat, in which the atria (the two small upper chambers of the heart) quiver instead of beating effectively. While there are a number of variations of atrial fibrillation with different causes, they all involve irregularities in the transmission of electrical impulses through the heart. As a result of abnormalities in the heart's electrical impulses, the heart is not able to pump the blood out properly, and it may pool and clot. If a blood clot moves to an artery in the brain, AF can lead to stroke. AF is also associated with increased risks of congestive heart failure and cardiomyopathy. These risks warrant medical attention for patients with AF even if the symptoms are mild. Atrial fibrillation is the most common sustained heart rhythm disorder and increases the risk for heart disease and stroke, both leading causes of death in the United States. Over 2 million adults in the United States have been diagnosed with atrial fibrillation.
Various ablation techniques have been proposed to treat atrial fibrillation, including the Cox-Maze procedure, linear ablation of various regions of the atrium, and circumferential pulmonary vein ablation. Each of these techniques has its various drawbacks. The Cox-Maze procedure and linear ablation procedures are tedious and time-consuming, taking up to several hours to accomplish endocardially. Circumferential ablation is proving to lead to rapid stenosis and occlusion of the pulmonary veins, and of course is not applicable to treatment of the septal wall of the left atrium. The catheter mounted electrode arrays described in our co-pending patent application Kunis, et al., Atrial Ablation Catheter and Method of Use, U.S. application Ser. No. 10/997,172 filed Nov. 22, 2004 provide for more efficient and effective treatment of atrial fibrillation. The treatment of the septal wall is facilitated with the devices and methods described below, which permit septal wall treatment from a percutaneous venous access route without the need to maneuver a distally facing electrode array in apposition to the septal wall.
The devices and methods described below provide for a simplified approach to the treatment of atrial fibrillation with substantially improved efficacy and outcomes in patients with paroxysmal or persistent atrial fibrillation, especially for those arrhythmia originating from, or sustained by, arrhythmogenic foci located on the septal wall of the left atrium. An endocardial catheter with an electrode array particularly adapted to locate and ablate foci of arrhythmia which are required for sustained atrial fibrillation is provided. The array is easily deployed and retracted from the catheter, and presents a proximally oriented electrode array that can be pulled against the septal wall of the left atrium to engage the septal wall. A control system comprising an ECG analyzer and a RF power supply operates to analyze electrical signals obtained from the electrode array, determine if an arrhythmogenic focus is present in the area covered by the array, and supply RF power to appropriate electrodes to ablate the focus.
a is an enlarged view of the electrode array in its expanded configuration.
b illustrates the meaning of the terminology which precisely defines the electrode array of
a is an end view of the electrode array, with an asymmetric arrangement of electrodes, in its expanded configuration.
a illustrates an alternate geometry of the septal wall array.
b illustrates the meaning of the terminology which precisely defines the electrode array of
To accomplish ablation of the septal wall of the left atrium, a catheter is inserted into the atrium, preferably through the inferior vena cava 20, as shown in the illustration, or through the superior vena cava 21, into the right atrium and then into left atrium. When passing into the left atrium, as illustrated, the catheter penetrates the fossa ovalis (a trans-septal puncture will facilitate the crossing). The catheter 22 carries a distal electrode array 23 into the atrium, and this electrode array is adapted to be pulled into contact with the section of the atrial wall surrounding the fossa ovalis. The electrode array is electrically connected to circuitry in a control system 24 which is operable to analyze electrical signals detected by the electrodes and pass RF current through the electrodes and heart tissue to ablate the tissue. A surface electrode 25 is mounted on the patient's body (typically on the back) to permit use of the electrodes in monopolar modes. A return electrode 26 may also be provided on the catheter 22, proximal to the electrode array. Using the catheter, an electrophysiologist will map regions of the septal wall of the left atrium and apply energy through the catheter to ablate any arrhythmogenic foci which are identified in the mapping procedure. The procedure may be repeated as necessary on the septal wall, rotating the array if necessary, to ablate all detected foci.
The electrode array includes a number electrodes 40 mounted on the proximal section 42 of each array arm, and the distal section 41 need not have any electrodes disposed on it, as is shown. The overall shape of each arm is elongate on an axis perpendicular to the long axis of the catheter, having a radial length R which is several times the axial length A.
The resilient expansion of the electrode array pushes the floating tube 44 proximally into the inner catheter tube. When the outer catheter tube is pushed distally over the electrode array, the distal electrode arms will be forced distally, as the proximal segments are compressed inwardly starting from the proximal end, to first splay the distal segments toward and through a perpendicular relationship with the floating tube such that the joint between the arms and the floating tube is distal to the bend point, while drawing the floating tube distally within the inner catheter tube.
a illustrate an alternate geometry of the septal wall array. The outer catheter tube 34 has been withdrawn proximally over the catheter inner tube, allowing the array arms 39 to expand to create array elements defining a substantially sagittate proximal outline. We use the term sagittate as that term is used in botany, where it describes a leaf with a base (where the leaf attaches to the stem) which is arrow-shaped (the back end of the arrow), having sharply triangular lobes with generally straight sides at the base which bend proximally away from the tip and then sharply turn distally toward the tip of the leaf, as shown in
After contact has been established between the atrium wall and the electrode array, the operator will analyze electrical signals detected by the electrodes to determine if the array has been placed over an arrhythmogenic focus. If it has, the operator may energize any of the electrodes, as appropriate, to ablate the focus. Bipolar RF energy may be applied between pairs of the electrodes, or monopolar energy may be applied to any of the electrodes (grounded to the surface electrode or a return electrode located proximally on the catheter body). The array may moved off the septal wall, rotated slightly, and reseated against the septal wall to test and treat the entire area surrounding the fossa ovalis with just a few array arms (alternatively, the array may be provided with many arms, such that the electrode density it sufficient to find an ablate all significant foci within its footprint). Linear lesions may be created using the electrodes along a single proximal arm, operating the electrodes in bipolar mode, and other therapeutic lesions may be created using electrodes pairs established between the electrodes of one arm and the electrodes of another arm, operating such pairs in bipolar mode, or operating electrodes in conjunction with return electrodes in a monopolar mode.
While the preferred embodiments of the devices and methods have been described in reference to the environment in which they were developed, they are merely illustrative of the principles of the inventions. Other embodiments and configurations may be devised without departing from the spirit of the inventions and the scope of the appended claims.
This application is a continuation of U.S. patent application Ser. No. 10/997,713, filed Nov. 24, 2004, and entitled “Atrial Ablation Catheter Adapted for Treatment of Septal Wall Arrhythmogenic Foci and Method of Use”, now U.S. Pat. No. 7,468,062, issued Dec. 23, 2008. All publications and patent applications mentioned in this specification are herein incorporated by reference to the same extent as if each individual publication or patent application was specifically and individually indicated to be incorporated by reference.
Number | Name | Date | Kind |
---|---|---|---|
3516412 | Ackerman | Jun 1970 | A |
3951136 | Wall | Apr 1976 | A |
4017903 | Chu | Apr 1977 | A |
4112952 | Thomas et al. | Sep 1978 | A |
4411266 | Cosman | Oct 1983 | A |
4432377 | Dickhudt | Feb 1984 | A |
4660571 | Hess et al. | Apr 1987 | A |
4699147 | Chilson et al. | Oct 1987 | A |
4785815 | Cohen | Nov 1988 | A |
4860769 | Fogarty et al. | Aug 1989 | A |
4869248 | Narula | Sep 1989 | A |
4882777 | Narula | Nov 1989 | A |
4896671 | Cunningham et al. | Jan 1990 | A |
4907589 | Cosman | Mar 1990 | A |
4920980 | Jackowski | May 1990 | A |
4940064 | Desai | Jul 1990 | A |
4966597 | Cosman | Oct 1990 | A |
5010894 | Edhag | Apr 1991 | A |
5016808 | Heil, Jr. et al. | May 1991 | A |
5083565 | Parins | Jan 1992 | A |
5100423 | Fearnot | Mar 1992 | A |
5156151 | Imran | Oct 1992 | A |
5184621 | Vogel et al. | Feb 1993 | A |
5215103 | Desai | Jun 1993 | A |
5228442 | Imran | Jul 1993 | A |
5230349 | Langberg | Jul 1993 | A |
5231987 | Robson | Aug 1993 | A |
5231995 | Desai | Aug 1993 | A |
5234004 | Hascoet et al. | Aug 1993 | A |
5239999 | Imran | Aug 1993 | A |
5255679 | Imran | Oct 1993 | A |
5279299 | Imran | Jan 1994 | A |
5281213 | Milder et al. | Jan 1994 | A |
5281218 | Imran | Jan 1994 | A |
5309910 | Edwards et al. | May 1994 | A |
5313943 | Houser et al. | May 1994 | A |
5318525 | West et al. | Jun 1994 | A |
5324284 | Imran | Jun 1994 | A |
5327889 | Imran | Jul 1994 | A |
5330466 | Imran | Jul 1994 | A |
5334193 | Nardella | Aug 1994 | A |
5342295 | Imran | Aug 1994 | A |
5342357 | Nardella | Aug 1994 | A |
5345936 | Pomeranz et al. | Sep 1994 | A |
5348554 | Imran et al. | Sep 1994 | A |
D351652 | Thompson et al. | Oct 1994 | S |
5364352 | Cimino et al. | Nov 1994 | A |
5365926 | Desai | Nov 1994 | A |
5370644 | Langberg | Dec 1994 | A |
5383917 | Desai et al. | Jan 1995 | A |
5391147 | Imran et al. | Feb 1995 | A |
5397304 | Truckai | Mar 1995 | A |
5397339 | Desai | Mar 1995 | A |
5400783 | Pomeranz et al. | Mar 1995 | A |
5404638 | Imran | Apr 1995 | A |
5406946 | Imran | Apr 1995 | A |
5411025 | Webster, Jr. | May 1995 | A |
5423808 | Edwards et al. | Jun 1995 | A |
5423811 | Imran et al. | Jun 1995 | A |
5433198 | Desai | Jul 1995 | A |
5433739 | Sluijter et al. | Jul 1995 | A |
5445148 | Jaraczewski et al. | Aug 1995 | A |
5462521 | Brucker et al. | Oct 1995 | A |
5462545 | Wang et al. | Oct 1995 | A |
5465717 | Imran et al. | Nov 1995 | A |
5471982 | Edwards et al. | Dec 1995 | A |
5487757 | Truckai et al. | Jan 1996 | A |
5492119 | Abrams | Feb 1996 | A |
5500011 | Desai | Mar 1996 | A |
5507802 | Imran | Apr 1996 | A |
5509411 | Littmann et al. | Apr 1996 | A |
5527279 | Imran | Jun 1996 | A |
5533967 | Imran | Jul 1996 | A |
5536267 | Edwards et al. | Jul 1996 | A |
5540681 | Strul et al. | Jul 1996 | A |
5545161 | Imran | Aug 1996 | A |
5545193 | Fleischman et al. | Aug 1996 | A |
5545200 | West et al. | Aug 1996 | A |
5558073 | Pomeranz et al. | Sep 1996 | A |
5573533 | Strul | Nov 1996 | A |
5575766 | Swartz et al. | Nov 1996 | A |
5575810 | Swanson et al. | Nov 1996 | A |
5578007 | Imran | Nov 1996 | A |
5582609 | Swanson et al. | Dec 1996 | A |
5584830 | Ladd et al. | Dec 1996 | A |
5588432 | Crowley | Dec 1996 | A |
5588964 | Imran et al. | Dec 1996 | A |
5595183 | Swanson et al. | Jan 1997 | A |
5596995 | Sherman et al. | Jan 1997 | A |
5598848 | Swanson et al. | Feb 1997 | A |
5601088 | Swanson et al. | Feb 1997 | A |
5606974 | Castellano et al. | Mar 1997 | A |
5607462 | Imran | Mar 1997 | A |
5620481 | Desai et al. | Apr 1997 | A |
5626136 | Webster, Jr. | May 1997 | A |
5630425 | Panescu et al. | May 1997 | A |
5630837 | Crowley | May 1997 | A |
5637090 | McGee et al. | Jun 1997 | A |
D381076 | Thornton et al. | Jul 1997 | S |
5645064 | Littmann et al. | Jul 1997 | A |
5645082 | Sung et al. | Jul 1997 | A |
5656029 | Imran et al. | Aug 1997 | A |
5657755 | Desai | Aug 1997 | A |
5658278 | Imran et al. | Aug 1997 | A |
5662606 | Cimino et al. | Sep 1997 | A |
5666970 | Smith | Sep 1997 | A |
5673695 | McGee et al. | Oct 1997 | A |
5680860 | Imran | Oct 1997 | A |
5681280 | Rusk et al. | Oct 1997 | A |
5682885 | Littmann et al. | Nov 1997 | A |
5685322 | Sung et al. | Nov 1997 | A |
5687723 | Avitall | Nov 1997 | A |
5693078 | Desai et al. | Dec 1997 | A |
5697927 | Imran et al. | Dec 1997 | A |
5697928 | Walcott et al. | Dec 1997 | A |
5699796 | Littmann et al. | Dec 1997 | A |
5702438 | Avitall | Dec 1997 | A |
5704791 | Gillio | Jan 1998 | A |
5706809 | Littmann et al. | Jan 1998 | A |
5711298 | Littmann et al. | Jan 1998 | A |
5716389 | Walinsky et al. | Feb 1998 | A |
5722401 | Pietroski et al. | Mar 1998 | A |
5722975 | Edwards et al. | Mar 1998 | A |
5724985 | Snell et al. | Mar 1998 | A |
5733323 | Buck et al. | Mar 1998 | A |
5735280 | Sherman et al. | Apr 1998 | A |
5741320 | Thornton et al. | Apr 1998 | A |
5766152 | Morley et al. | Jun 1998 | A |
5769791 | Benaron et al. | Jun 1998 | A |
5769847 | Panescu et al. | Jun 1998 | A |
5772590 | Webster, Jr. | Jun 1998 | A |
5775327 | Randolph et al. | Jul 1998 | A |
5782239 | Webster, Jr. | Jul 1998 | A |
5782760 | Schaer | Jul 1998 | A |
5782828 | Chen et al. | Jul 1998 | A |
5782899 | Imran | Jul 1998 | A |
5792140 | Tu et al. | Aug 1998 | A |
5800482 | Pomeranz et al. | Sep 1998 | A |
5810740 | Paisner | Sep 1998 | A |
5820568 | Willis | Oct 1998 | A |
5827272 | Breining et al. | Oct 1998 | A |
5837001 | Mackey | Nov 1998 | A |
5849028 | Chen | Dec 1998 | A |
5857464 | Desai | Jan 1999 | A |
5857997 | Cimino et al. | Jan 1999 | A |
5860920 | McGee et al. | Jan 1999 | A |
5863291 | Schaer | Jan 1999 | A |
5871523 | Fleischman et al. | Feb 1999 | A |
5873865 | Horzewski et al. | Feb 1999 | A |
5876399 | Chia et al. | Mar 1999 | A |
5881732 | Sung et al. | Mar 1999 | A |
5882333 | Schaer et al. | Mar 1999 | A |
5885278 | Fleischman | Mar 1999 | A |
5891027 | Tu et al. | Apr 1999 | A |
5891135 | Jackson et al. | Apr 1999 | A |
5891137 | Chia et al. | Apr 1999 | A |
5891138 | Tu et al. | Apr 1999 | A |
5893847 | Kordis | Apr 1999 | A |
5893884 | Tu | Apr 1999 | A |
5893885 | Webster, Jr. | Apr 1999 | A |
5895355 | Schaer | Apr 1999 | A |
5895417 | Pomeranz et al. | Apr 1999 | A |
5897554 | Chia et al. | Apr 1999 | A |
5904680 | Kordis et al. | May 1999 | A |
5906605 | Coxum | May 1999 | A |
5910129 | Koblish et al. | Jun 1999 | A |
5911720 | Bourne et al. | Jun 1999 | A |
5913854 | Maguire et al. | Jun 1999 | A |
5916214 | Cosio et al. | Jun 1999 | A |
5928191 | Houser et al. | Jul 1999 | A |
5931835 | Mackey | Aug 1999 | A |
5935063 | Nguyen | Aug 1999 | A |
5938694 | Jaraczewski et al. | Aug 1999 | A |
5941845 | Tu et al. | Aug 1999 | A |
5951471 | de la Rama et al. | Sep 1999 | A |
5954719 | Chen et al. | Sep 1999 | A |
5957842 | Littmann et al. | Sep 1999 | A |
5960796 | Sung et al. | Oct 1999 | A |
5967978 | Littmann et al. | Oct 1999 | A |
5968040 | Swanson et al. | Oct 1999 | A |
5971980 | Sherman | Oct 1999 | A |
5992418 | de la Rama et al. | Nov 1999 | A |
5997532 | McLaughlin et al. | Dec 1999 | A |
6001093 | Swanson et al. | Dec 1999 | A |
6001095 | de la Rama et al. | Dec 1999 | A |
6002956 | Schaer | Dec 1999 | A |
6004269 | Crowley et al. | Dec 1999 | A |
6014581 | Whayne et al. | Jan 2000 | A |
6021340 | Randolph et al. | Feb 2000 | A |
6023638 | Swanson | Feb 2000 | A |
6029091 | de la Rama et al. | Feb 2000 | A |
6032674 | Eggers et al. | Mar 2000 | A |
6033403 | Tu et al. | Mar 2000 | A |
6042580 | Simpson | Mar 2000 | A |
6045550 | Simpson et al. | Apr 2000 | A |
6048329 | Thompson et al. | Apr 2000 | A |
6049737 | Simpson et al. | Apr 2000 | A |
6050994 | Sherman | Apr 2000 | A |
6052612 | Desai | Apr 2000 | A |
6053937 | Edwards et al. | Apr 2000 | A |
6056744 | Edwards | May 2000 | A |
6059778 | Sherman | May 2000 | A |
6063077 | Schaer | May 2000 | A |
6063082 | DeVore et al. | May 2000 | A |
6064902 | Haissaguerre et al. | May 2000 | A |
6068629 | Haissaguerre et al. | May 2000 | A |
6070094 | Swanson et al. | May 2000 | A |
6071274 | Thompson et al. | Jun 2000 | A |
6071279 | Whayne et al. | Jun 2000 | A |
6071281 | Burnside et al. | Jun 2000 | A |
6071282 | Fleischman | Jun 2000 | A |
6074351 | Houser | Jun 2000 | A |
6086581 | Reynolds et al. | Jul 2000 | A |
6088610 | Littmann et al. | Jul 2000 | A |
6096036 | Bowe et al. | Aug 2000 | A |
6099524 | Lipson et al. | Aug 2000 | A |
6106522 | Fleischman et al. | Aug 2000 | A |
6107699 | Swanson | Aug 2000 | A |
6115626 | Whayne et al. | Sep 2000 | A |
6119041 | Pomeranz et al. | Sep 2000 | A |
6120476 | Fung et al. | Sep 2000 | A |
6129724 | Fleischman et al. | Oct 2000 | A |
6141576 | Littmann et al. | Oct 2000 | A |
6146379 | Fleischman et al. | Nov 2000 | A |
6146381 | Bowe et al. | Nov 2000 | A |
6165169 | Panescu et al. | Dec 2000 | A |
6167291 | Barajas et al. | Dec 2000 | A |
6171305 | Sherman | Jan 2001 | B1 |
6171306 | Swanson et al. | Jan 2001 | B1 |
6179833 | Taylor | Jan 2001 | B1 |
6200314 | Sherman | Mar 2001 | B1 |
6212426 | Swanson | Apr 2001 | B1 |
6214002 | Fleischman et al. | Apr 2001 | B1 |
6216043 | Swanson et al. | Apr 2001 | B1 |
6216044 | Kordis | Apr 2001 | B1 |
6217573 | Webster | Apr 2001 | B1 |
6217576 | Tu et al. | Apr 2001 | B1 |
6226542 | Reisfeld | May 2001 | B1 |
6231570 | Tu et al. | May 2001 | B1 |
6238390 | Tu et al. | May 2001 | B1 |
6241666 | Pomeranz et al. | Jun 2001 | B1 |
6241724 | Fleischman et al. | Jun 2001 | B1 |
6241725 | Cosman | Jun 2001 | B1 |
6241726 | Raymond et al. | Jun 2001 | B1 |
6241727 | Tu et al. | Jun 2001 | B1 |
6241728 | Gaiser et al. | Jun 2001 | B1 |
6241754 | Swanson et al. | Jun 2001 | B1 |
6245067 | Tu et al. | Jun 2001 | B1 |
6245089 | Daniel et al. | Jun 2001 | B1 |
6251107 | Schaer | Jun 2001 | B1 |
6256540 | Panescu et al. | Jul 2001 | B1 |
6264664 | Avellanet | Jul 2001 | B1 |
6267746 | Bumbalough | Jul 2001 | B1 |
6290697 | Tu et al. | Sep 2001 | B1 |
6293943 | Panescu et al. | Sep 2001 | B1 |
6302880 | Schaer | Oct 2001 | B1 |
6309385 | Simpson | Oct 2001 | B1 |
6312425 | Simpson et al. | Nov 2001 | B1 |
6319251 | Tu et al. | Nov 2001 | B1 |
6325797 | Stewart et al. | Dec 2001 | B1 |
6332880 | Yang et al. | Dec 2001 | B1 |
6332881 | Carner et al. | Dec 2001 | B1 |
6346104 | Daly et al. | Feb 2002 | B2 |
6353751 | Swanson | Mar 2002 | B1 |
6360128 | Kordis et al. | Mar 2002 | B2 |
6370435 | Panescu et al. | Apr 2002 | B2 |
6371955 | Fuimaono et al. | Apr 2002 | B1 |
6379352 | Reynolds et al. | Apr 2002 | B1 |
6389311 | Whayne et al. | May 2002 | B1 |
6391024 | Sun et al. | May 2002 | B1 |
6425894 | Brucker et al. | Jul 2002 | B1 |
6428536 | Panescu et al. | Aug 2002 | B2 |
6428537 | Swanson et al. | Aug 2002 | B1 |
6440129 | Simpson | Aug 2002 | B1 |
6447506 | Swanson et al. | Sep 2002 | B1 |
6451015 | Rittman, III et al. | Sep 2002 | B1 |
6454758 | Thompson et al. | Sep 2002 | B1 |
6456864 | Swanson et al. | Sep 2002 | B1 |
6460545 | Kordis | Oct 2002 | B2 |
6471693 | Carroll et al. | Oct 2002 | B1 |
6471699 | Fleischman et al. | Oct 2002 | B1 |
6475213 | Whayne et al. | Nov 2002 | B1 |
6475214 | Moaddeb | Nov 2002 | B1 |
6477396 | Mest et al. | Nov 2002 | B1 |
6478793 | Cosman et al. | Nov 2002 | B1 |
6485487 | Sherman | Nov 2002 | B1 |
6487441 | Swanson et al. | Nov 2002 | B1 |
6488678 | Sherman | Dec 2002 | B2 |
6490468 | Panescu et al. | Dec 2002 | B2 |
6493586 | Stahmann et al. | Dec 2002 | B1 |
6500167 | Webster, Jr. | Dec 2002 | B1 |
6500172 | Panescu et al. | Dec 2002 | B1 |
6514246 | Swanson et al. | Feb 2003 | B1 |
6517536 | Hooven et al. | Feb 2003 | B2 |
6522905 | Desai | Feb 2003 | B2 |
6529756 | Phan et al. | Mar 2003 | B1 |
6540744 | Hassett et al. | Apr 2003 | B2 |
6542773 | Dupree et al. | Apr 2003 | B2 |
6544262 | Fleischman | Apr 2003 | B2 |
6551271 | Nguyen | Apr 2003 | B2 |
6554794 | Mueller et al. | Apr 2003 | B1 |
6558378 | Sherman et al. | May 2003 | B2 |
6565511 | Panescu et al. | May 2003 | B2 |
6569114 | Ponzi et al. | May 2003 | B2 |
6569162 | He | May 2003 | B2 |
6569163 | Hata et al. | May 2003 | B2 |
6572612 | Stewart et al. | Jun 2003 | B2 |
6574492 | Ben-Haim et al. | Jun 2003 | B1 |
6575997 | Palmer et al. | Jun 2003 | B1 |
6583796 | Jamar et al. | Jun 2003 | B2 |
6597955 | Panescu et al. | Jul 2003 | B2 |
6602242 | Fung et al. | Aug 2003 | B1 |
6605087 | Swartz et al. | Aug 2003 | B2 |
6607505 | Thompson et al. | Aug 2003 | B1 |
6607520 | Keane | Aug 2003 | B2 |
6616657 | Simpson et al. | Sep 2003 | B2 |
6625482 | Panescu et al. | Sep 2003 | B1 |
6628976 | Fuimaono et al. | Sep 2003 | B1 |
6632223 | Keane | Oct 2003 | B1 |
6635056 | Kadhiresan et al. | Oct 2003 | B2 |
6638223 | Lifshitz et al. | Oct 2003 | B2 |
6638275 | McGaffigan et al. | Oct 2003 | B1 |
6640120 | Swanson et al. | Oct 2003 | B1 |
6652513 | Panescu et al. | Nov 2003 | B2 |
6652517 | Hall et al. | Nov 2003 | B1 |
6658279 | Swanson et al. | Dec 2003 | B2 |
6669692 | Nelson et al. | Dec 2003 | B1 |
6669693 | Friedman | Dec 2003 | B2 |
6671533 | Chen et al. | Dec 2003 | B2 |
6690972 | Conley et al. | Feb 2004 | B2 |
6701180 | Desai | Mar 2004 | B1 |
6702811 | Stewart et al. | Mar 2004 | B2 |
6711428 | Fuimaono et al. | Mar 2004 | B2 |
6730078 | Simpson et al. | May 2004 | B2 |
6738673 | Desai | May 2004 | B2 |
6740080 | Jain et al. | May 2004 | B2 |
6743225 | Sanchez et al. | Jun 2004 | B2 |
6746446 | Hill, III et al. | Jun 2004 | B1 |
6752804 | Simpson et al. | Jun 2004 | B2 |
6761716 | Kadhiresan et al. | Jul 2004 | B2 |
6805131 | Kordis | Oct 2004 | B2 |
6813520 | Truckai et al. | Nov 2004 | B2 |
6814732 | Schaer | Nov 2004 | B2 |
6830576 | Fleischman et al. | Dec 2004 | B2 |
6866662 | Fuimaono et al. | Mar 2005 | B2 |
6893438 | Hall et al. | May 2005 | B2 |
6893439 | Fleischman | May 2005 | B2 |
6893442 | Whayne | May 2005 | B2 |
6916306 | Jenkins et al. | Jul 2005 | B1 |
6936047 | Nasab et al. | Aug 2005 | B2 |
6939349 | Fleischman et al. | Sep 2005 | B2 |
6952615 | Satake | Oct 2005 | B2 |
6955173 | Lesh | Oct 2005 | B2 |
6960206 | Keane | Nov 2005 | B2 |
6961602 | Fuimaono et al. | Nov 2005 | B2 |
6964660 | Maguire et al. | Nov 2005 | B2 |
6966908 | Maguire et al. | Nov 2005 | B2 |
6972016 | Hill, III et al. | Dec 2005 | B2 |
6973339 | Govari | Dec 2005 | B2 |
6987995 | Drysen | Jan 2006 | B2 |
7001336 | Mandrusov et al. | Feb 2006 | B2 |
7025766 | Whayne et al. | Apr 2006 | B2 |
7029470 | Francischelli et al. | Apr 2006 | B2 |
7029471 | Thompson et al. | Apr 2006 | B2 |
7044135 | Lesh | May 2006 | B2 |
7047068 | Haissaguerre | May 2006 | B2 |
7048734 | Fleischman et al. | May 2006 | B1 |
7048756 | Eggers et al. | May 2006 | B2 |
7077823 | McDaniel | Jul 2006 | B2 |
7094235 | Francischelli | Aug 2006 | B2 |
7099711 | Fuimaono et al. | Aug 2006 | B2 |
7099712 | Fuimaono et al. | Aug 2006 | B2 |
7113831 | Hooven | Sep 2006 | B2 |
7115122 | Swanson et al. | Oct 2006 | B1 |
7118568 | Hassett et al. | Oct 2006 | B2 |
7122031 | Edwards et al. | Oct 2006 | B2 |
7151964 | Desai et al. | Dec 2006 | B2 |
7155270 | Solis et al. | Dec 2006 | B2 |
7156843 | Skarda | Jan 2007 | B2 |
7163537 | Lee et al. | Jan 2007 | B2 |
7429261 | Kunis et al. | Sep 2008 | B2 |
7857808 | Oral et al. | Dec 2010 | B2 |
20010029366 | Swanson et al. | Oct 2001 | A1 |
20010039415 | Francischelli et al. | Nov 2001 | A1 |
20010044625 | Hata et al. | Nov 2001 | A1 |
20010051803 | Desai et al. | Dec 2001 | A1 |
20020065465 | Panescu et al. | May 2002 | A1 |
20020120263 | Brown et al. | Aug 2002 | A1 |
20020126036 | Flaherty et al. | Sep 2002 | A1 |
20020161422 | Swanson et al. | Oct 2002 | A1 |
20030018330 | Swanson et al. | Jan 2003 | A1 |
20030093069 | Panescu et al. | May 2003 | A1 |
20030125730 | Berube et al. | Jul 2003 | A1 |
20030181819 | Desai | Sep 2003 | A1 |
20030195407 | Fuimaono et al. | Oct 2003 | A1 |
20030195501 | Sherman et al. | Oct 2003 | A1 |
20030199746 | Fuimaono et al. | Oct 2003 | A1 |
20030204185 | Sherman et al. | Oct 2003 | A1 |
20030204186 | Geistert | Oct 2003 | A1 |
20040015164 | Fuimaono et al. | Jan 2004 | A1 |
20040082947 | Oral et al. | Apr 2004 | A1 |
20040116921 | Sherman et al. | Jun 2004 | A1 |
20040133154 | Flaherty et al. | Jul 2004 | A1 |
20040138545 | Chen et al. | Jul 2004 | A1 |
20040143256 | Bednarek | Jul 2004 | A1 |
20040152980 | Desai | Aug 2004 | A1 |
20040158141 | Scheib | Aug 2004 | A1 |
20040181139 | Falwell et al. | Sep 2004 | A1 |
20040181249 | Torrance et al. | Sep 2004 | A1 |
20040182384 | Alfery | Sep 2004 | A1 |
20040236324 | Muller et al. | Nov 2004 | A1 |
20040247164 | Furnish | Dec 2004 | A1 |
20050010095 | Stewart et al. | Jan 2005 | A1 |
20050015084 | Hill et al. | Jan 2005 | A1 |
20050033137 | Oral et al. | Feb 2005 | A1 |
20050065512 | Schaer | Mar 2005 | A1 |
20050096644 | Hall et al. | May 2005 | A1 |
20050101946 | Govari et al. | May 2005 | A1 |
20050119651 | Fuimaono et al. | Jun 2005 | A1 |
20050148892 | Desai | Jul 2005 | A1 |
20050177146 | Sherman | Aug 2005 | A1 |
20050187545 | Hooven et al. | Aug 2005 | A1 |
20050234444 | Hooven | Oct 2005 | A1 |
20050240176 | Oral et al. | Oct 2005 | A1 |
20050251132 | Oral et al. | Nov 2005 | A1 |
20050256521 | Kozel | Nov 2005 | A1 |
20060030844 | Knight et al. | Feb 2006 | A1 |
20060084966 | Maguire et al. | Apr 2006 | A1 |
20060089637 | Werneth et al. | Apr 2006 | A1 |
20060095030 | Avitall et al. | May 2006 | A1 |
20060106375 | Werneth et al. | May 2006 | A1 |
20060111700 | Kunis et al. | May 2006 | A1 |
20060111701 | Oral et al. | May 2006 | A1 |
20060111702 | Oral et al. | May 2006 | A1 |
20060111703 | Kunis et al. | May 2006 | A1 |
20060111708 | Vanney et al. | May 2006 | A1 |
20060142753 | Francischelli et al. | Jun 2006 | A1 |
20060189975 | Whayne et al. | Aug 2006 | A1 |
20060195082 | Francischelli | Aug 2006 | A1 |
20060241366 | Falwell et al. | Oct 2006 | A1 |
20070083193 | Werneth et al. | Apr 2007 | A1 |
20070083194 | Kunis et al. | Apr 2007 | A1 |
20070083195 | Werneth et al. | Apr 2007 | A1 |
20070106293 | Oral et al. | May 2007 | A1 |
Number | Date | Country |
---|---|---|
5200671AA | Oct 2005 | AU |
2327322AA | Nov 1999 | CA |
2327518AA | Nov 1999 | CA |
2328064AA | Nov 1999 | CA |
2328070AA | Nov 1999 | CA |
2371935AA | Dec 2000 | CA |
2222617 | Jul 2002 | CA |
2437140AA | Jun 2004 | CA |
2492283AA | Jul 2005 | CA |
2194061 | Apr 2006 | CA |
2276755 | May 2006 | CA |
2251041 | Jun 2006 | CA |
428812 | Mar 1995 | EP |
779059 | Jun 1997 | EP |
598742 | Aug 1999 | EP |
879016 | Oct 2003 | EP |
1360938 | Nov 2003 | EP |
1364677 | Nov 2003 | EP |
1554986 | Jul 2005 | EP |
823843 | Oct 2005 | EP |
1384445 | Feb 2006 | EP |
1169976 | Apr 2006 | EP |
1415680 | Apr 2006 | EP |
1011437 | May 2006 | EP |
1210021 | May 2006 | EP |
1658818 | May 2006 | EP |
1125549 | Jun 2006 | EP |
1182980 | Jun 2006 | EP |
1207798 | Jun 2006 | EP |
1321166 | Jul 2006 | EP |
1343427 | Jul 2006 | EP |
828451 | Sep 2006 | EP |
1070480 | Sep 2006 | EP |
1014874 | Dec 2006 | EP |
1383437 | Dec 2006 | EP |
1455667 | Jan 2007 | EP |
957794 | Jul 2007 | EP |
2004188179 | Jul 2004 | JP |
1512622 | Oct 1989 | SU |
1544396 | Feb 1990 | SU |
1690786 | Nov 1991 | SU |
WO9006079 | Jun 1990 | WO |
WO9308756 | May 1993 | WO |
WO9325273 | Dec 1993 | WO |
WO9412098 | Jun 1994 | WO |
WO9610961 | Apr 1996 | WO |
WO9632885 | Oct 1996 | WO |
WO9632897 | Oct 1996 | WO |
WO9634558 | Nov 1996 | WO |
WO9634559 | Nov 1996 | WO |
WO9634560 | Nov 1996 | WO |
WO9634567 | Nov 1996 | WO |
WO9634569 | Nov 1996 | WO |
WO9634570 | Nov 1996 | WO |
WO9634650 | Nov 1996 | WO |
WO9634652 | Nov 1996 | WO |
WO9634653 | Nov 1996 | WO |
WO9636860 | Nov 1996 | WO |
WO9639967 | Dec 1996 | WO |
WO9715919 | May 1997 | WO |
WO9717893 | May 1997 | WO |
WO9717904 | May 1997 | WO |
WO9725917 | Jul 1997 | WO |
WO9725919 | Jul 1997 | WO |
WO9732525 | Sep 1997 | WO |
WO9736541 | Oct 1997 | WO |
WO9740760 | Nov 1997 | WO |
WO9742996 | Nov 1997 | WO |
WO9818520 | May 1998 | WO |
WO9819611 | May 1998 | WO |
WO9826724 | Jun 1998 | WO |
WO9828039 | Jul 1998 | WO |
WO9838913 | Sep 1998 | WO |
WO9902096 | Jan 1999 | WO |
WO9956644 | Nov 1999 | WO |
WO9956647 | Nov 1999 | WO |
WO9956648 | Nov 1999 | WO |
WO9956649 | Nov 1999 | WO |
WO0078239 | Dec 2000 | WO |
WO02060523 | Aug 2002 | WO |
WO03041602 | May 2003 | WO |
WO03089997 | Oct 2003 | WO |
WO2005027765 | Mar 2005 | WO |
WO2005027766 | Mar 2005 | WO |
WO2005065562 | Jul 2005 | WO |
WO2005065563 | Jul 2005 | WO |
WO2005104972 | Nov 2005 | WO |
WO2006017517 | Feb 2006 | WO |
WO2006044794 | Apr 2006 | WO |
WO2006049970 | May 2006 | WO |
WO2006052651 | May 2006 | WO |
WO2006052905 | May 2006 | WO |
WO2006055654 | May 2006 | WO |
WO2006055658 | May 2006 | WO |
WO2006055733 | May 2006 | WO |
WO2006055741 | May 2006 | WO |
Entry |
---|
Oral et al.; U.S. Appl. No. 11/932,378 entitled “Ablation catheters and methods for their use,” filed Oct. 31, 2007. |
“Werneth et al.; U.S. Appl. No. 12/116,753 entitled”“Ablation therapy system and method for treating continuous atrial fibrillation,”“filed May 7, 2008”. |
Sherman et. al. ; U.S. Appl. No. 12/117,596 entitled “RF energy delivery system and method,”filed May 8, 2008. |
Kunis et al.; U.S. Appl. No. 12/197,425 entitled “Atrial ablation catheter and method of use,” filed Aug. 25, 2008. |
Werneth et al.; U.S. Appl. No. 12/245,625 entitled “Ablation catheter,” filed Oct. 3, 2008. |
Nademanee et al., “A new approach for catheter ablation of atrial fibrillation: mapping of the electrophysiologic substrate,” JACC, vol. 43, No. 11, pp. 2044-2053, 2004. |
Wittkampf et al., “Radiofrequency ablation with a cooled porous electrode catheter,” (abstract) JACC, vol. 11, No. 2, pp. 17a, Feb. 1988. |
Number | Date | Country | |
---|---|---|---|
20080275443 A1 | Nov 2008 | US |
Number | Date | Country | |
---|---|---|---|
Parent | 10997713 | Nov 2004 | US |
Child | 12176115 | US |