Patent Grant
10653829
The present invention, in some embodiments thereof, relates to automatic injectors and, more particularly, but not exclusively, to a door block for proper insertion of a cartridge into an automatic injector.
U.S. Pat. No. 9,421,323 discloses a doorstop to a drug delivery apparatus that encourages a user of the apparatus to perform the proper usage steps in the proper order. For example, a user may be expected to receive an injector in a transport state, open it to an open state, insert a cartridge, and/or close the cartridge before operation. The doorstop may have an obstructing mode, optionally preventing closing of the door. The cartridge may optionally have a non-obstructing mode allowing closing of the door. Inserting the cartridge may optionally cause a doorstop to move from the obstructing mode to the non-obstructing mode. In the non-obstructing mode the doorstop may optionally prevent removal of the cartridge.
Additional background art includes U.S. Pat. Nos. 4,689,043, 5,090,877, 5,364,364, 5,445,621, 5,505,709, 5,779,676, 5,830,187, 5,954,697, 6,423,036, 6,599,272, U.S. Pat. Application Publication No. US2007/0197968, U.S. Patent Application Publication No. US2011/0066131, and International Application Publication No. WO2012032411A2.
Example 1. An automatic injector device for delivering a pharmaceutical substance from a cartridge having a protruding edge, the cartridge positioned in a housing of the device, the housing comprising a cartridge bay having an opening sized to allow passage of the cartridge into the cartridge bay; a door to the cartridge bay opening, the door connected to the housing and having an unlatched position and a latched position, the door defining a trajectory between the unlatched position and the latched position; an interference element having a deflected and an inflected orientation, the deflected orientation mechanically interferes with the trajectory of the door; and a contact interface positioned along the cartridge bay and extending up to the protruding edge, the contact interface mechanically couples the deflected and inflected orientation with a sensed contact of the protruding edge, such that when the protruding edge is positioned at the contact interface, the contact interface shifts the interference element into the inflected orientation.
Example 2. The device of example 1, wherein the door further comprises a coupling link, positioned to mechanically link the cartridge with a motor, when the door is in the latched position.
Example 3. The device of example 2, wherein the coupling link comprises a gear having cogs complementary to a powering gear of the motor and a driving gear of the cartridge.
Example 4. The device of example 3, wherein the driving gear is mechanically coupled to a plunger residing within the cartridge.
Example 5. The device of example 1, wherein the contact interface is positioned at a rim of the opening of the cartridge bay.
Example 6. The device of example 1, wherein the contact interface is elastic.
Example 7. The device of example 6, wherein the deflected orientation comprises an unstressed configuration of the interference element and the inflected orientation comprises a stressed configuration of the interference element.
Example 8. The device of example 6, wherein the contact interface mechanically interferes with a location of the protruding edge of the cartridge residing beyond the rim and outside of the cartridge bay.
Example 9. The device of example 8, wherein the location comprises a range of about 0.5 mm to about 3 mm beyond the rim and outside of the cartridge bay.
Example 10. The device of example 1, further comprising a cartridge lock positioned at the rim.
Example 11. The device of example 10, wherein the cartridge lock comprises a snap mechanism shaped to snap over a proximal edge of the cartridge and mechanically press against the cartridge, when the cartridge is positioned in the cartridge bay and the protruding edge contacts the contacts interface.
Example 12. The device of example 1, wherein a transition from the unlatched position to the latched position of the door is irrevocable.
Example 13. The device of example 12, wherein the door is pivotable about a first axis parallel to the cartridge bay and wherein the door is rotatable about a second axis which is perpendicular to the first axis.
Example 14. A method for amplifying a position of a cartridge having a protruding edge in a housing of an automatic injector, the housing having a door for closing the cartridge inserted into a cartridge bay of the housing, comprising mechanically interfering with a trajectory of closing the door through a deflected interference element; inserting the cartridge into the cartridge bay of the housing; pressing the protruding edge of the cartridge against a contact interface positioned along the cartridge bay, the contact interface mechanically coupled to the deflected interference element; shifting the position of the contact interface, thereby inflecting the interference element away from the trajectory of the door; and latching the door in a closed position.
Example 15. The method of example 14, wherein the latching the door in the closed position further comprises positioning a coupling link between a driving system of the cartridge and a motor of the injector.
Example 16. The method of example 14, wherein the inserting the cartridge further comprises inserting at least 95% of the cartridge before the protruding edge of the cartridge is pressed against the contact interface.
Example 17. The method of example 16, further comprising pushing the cartridge away from the cartridge bay when less than 95% of the cartridge is inserted.
Example 18. The method of example 17, wherein the pushing comprises preventing a proximal edge of the cartridge from residing in a range of about 0.5 mm to about 3 mm outside of the cartridge bay.
Example 19. The method of example 14, further comprising locking a position of the cartridge following the pressing of the protruding edge against the contact interface.
Example 20. The method of example 19, wherein the locking a position of the cartridge comprises locking the pressing of the protruding edge against the contact interface and locking the interference element in an inflected orientation.
Unless otherwise defined, all technical and/or scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which the invention pertains. Although methods and materials similar or equivalent to those described herein can be used in the practice or testing of embodiments of the invention, exemplary methods and/or materials are described below. In case of conflict, the patent specification, including definitions, will control. In addition, the materials, methods, and examples are illustrative only and are not intended to be necessarily limiting.
Some embodiments of the invention are herein described, by way of example only, with reference to the accompanying drawings. With specific reference now to the drawings in detail, it is stressed that the particulars shown are by way of example and for purposes of illustrative discussion of embodiments of the invention. In this regard, the description taken with the drawings makes apparent to those skilled in the art how embodiments of the invention may be practiced.
In the drawings:
The present invention, in some embodiments thereof, relates to automatic injectors and, more particularly, but not exclusively, to a door block for proper insertion of a cartridge into an automatic injector.
An aspect of some embodiments of the invention relates to preventing an automatic injector door from locking into a closed position, as long as a cartridge is not inserted into the injector and/or as long as a cartridge is inserted but not properly positioned. In some embodiments, an improper position of the cartridge includes an improper mechanical interface, for example, an improper mechanical coupling of the cartridge to a motor and/or a gear of the injector. Alternatively or additionally, an improper position of the cartridge includes an improper fluid interface, for example, improper positioning of the cartridge with respect to the fluid path, for example, improper coupling of the cartridge with the needle, and/or improper positioning of a cartridge having a needle in the correct needle path of the injector. As used herein, a door comprises a cover which is fixed to the injector housing in one end, and allowed to transition between different states of covering the housing.
In some embodiments, an automatic injector comprises a door having a latching mechanism. Typically, an injector door is being closed once a cartridge is placed within the injector. A cartridge may be filled and/or pre-filled with a pharmaceutical substance, which may include for example, a drug, and/or placebo, and/or a nutritional supplement or the like. In some embodiments, a cartridge has a distal side being in fluid communication with a needle of the injector, and a proximal side having a plunger for driving the fluid through the fluid path. In order for the injector to work properly, a cartridge needs to have both a correct mechanical interface, permitting proper driving of the plunger, and a correct fluid interface permitting proper fluid communication from the cartridge to the needle and into an injection subject.
Optionally, the latching mechanism causes the door to close irrevocably, potentially identifying a used injector and preventing reuse of a disposable injector. In some embodiments, a cartridge which is not inserted properly into the injector interferes with a closing trajectory of the door and prevents its latching. Alternatively or additionally, an amplifier, which is affected by the cartridge position, mechanically interferes with closing the door when the cartridge is positioned improperly. It is a potential advantage to prevent a door from irrevocably closing without an inserted cartridge, for example, when preventing automatic injector devices from closing during transit. It is a potential advantage to prevent a door from irrevocably closing when the cartridge is not properly inserted, because operating the device while the cartridge is not in a proper position might result in fluid which would not be injected or be injected not through the fluid path, for example resulting in leakage. Alternatively or additionally, improper cartridge position may lead to gear malfunction and/or breakage.
An aspect of some embodiments of the invention relates to inhibiting operational communication to a cartridge of an automatic injector until the cartridge is sufficiently inserted into the injector device. In some embodiments, operational communication comprises engaging a driving mechanism with the cartridge, for example, by mechanically coupling a gear system to a plunger residing within the cartridge. In some embodiments, a mechanical coupling link is provided, optionally, being coupled to the injector door, for example, on an inner wall of the door.
In some embodiments, operational communication is determined by a state of a mechanical coupling link between the driving mechanism of the cartridge and a motor of the injector. For example, a coupling link may be a gear linking between a gear of the motor and a gear of the driving system of the plunger. Optionally, the state of the coupling link is characterized by at least two positions; an engaged position which enables mechanical operable communication between the cartridge and the motor, and a disengaged position in which the motor is disconnected from the driving mechanism of the cartridge. In some embodiments, an improper position of the cartridge prevents the coupling link to enter its engaged position.
In some embodiments, an injector comprises a cartridge bay sized and shaped for accommodating the cartridge, and having an opening for inserting the cartridge therethrough. Optionally, an injector door is hingedly connected to one side of the injector base, and is pivotally movable to its closing position resulting in covering the cartridge bay opening. In some embodiments, the door comprises a latching mechanism at the side of the door opposite to the hinge, and for locking with a complementary lock residing in the injector base opposite to the hinged connection with the door. In some embodiments, when the door is pivotally moved over the opening of the cartridge bay it defines a movement trajectory. Optionally, a coupling link residing in the door comprises a movement trajectory which follows the movement trajectory of the door. In some embodiments, a user gets a tactile feeling that the cartridge is misplaced by not being able to properly latch the door to the housing.
When the cartridge is improperly inserted into the injector, in some embodiments, the cartridge itself mechanically interferes with an engaged position of the coupling link. Optionally, a protruding edge of the cartridge interferes with a trajectory of positioning the coupling link. In some embodiments, a protruding edge includes a flange, and/or a bevel, and/or a knob, and/or a bulge. Optionally, the protruding edge extends along the entire perimeter of the cartridge, potentially enabling insertion of the cartridge without being sensitive to its rotational orientation.
Alternatively or additionally, when the cartridge is improperly positioned, an interference element mechanically interferes with transitioning the coupling link into its engaged position. Alternatively or additionally, an interference element mechanically interferes with the trajectory of closing the injector door. In some embodiments, the interference element is mechanically coupled to a sensor which detects the position of the cartridge. Optionally, the sensor couples an improper position of the cartridge with a presence of the interference element in the trajectory of the door and/or coupling link. Alternatively or additionally, the sensor couples a proper position of the cartridge with removing the interference element from the trajectory of the door and/or coupling link.
Optionally, the sensor is elastic. In some embodiments, when the cartridge is not fully inserted, the elastic sensor exerts a force on the cartridge, pushing it away from the cartridge bay, thereby enhancing the improper position of the cartridge. A potential advantage of enhancing the improper position of the cartridge is to prevent a user from operating an injector when the cartridge is positioned within the injector, but not in a proper manner. System failures sometimes occur when a device door is closed prematurely, without noticing the cartridge is not properly positioned. For example, in some cases a user may close the device door before inserting the cartridge fully into the injector. In other cases, the device door may close during transit. Some solutions prevent closing the door until the cartridge has been at least partially inserted, but do not prevent closing the door when the cartridge has been partially, but not fully, inserted.
Premature coupling of the driving mechanism with the plunger, may sometimes lead to system failure, potentially resulting in breakage of components of the injector and/or interfering with the injection of the injectable substance to a user of the injector.
In some embodiments, a sensor, for example a cartridge contact interface, detects the presence of the cartridge in a location proximal to the cartridge bay. In some embodiments, a sensor positioned at the rim of the opening of the cartridge bay provides mechanical feedback to the positioning of the cartridge with respect to the rim of the cartridge bay. In some embodiments, the sensor is elastic. In some embodiments, the sensor is positioned to be insensitive to the body of the cartridge, but to mechanically contact a distinct cross-section of the cartridge proximal end, for example a protruding edge.
In some embodiments, the sensor also prevent the cartridge from residing in a location being just outside the cartridge bay, forcing the cartridge to a location being even more remote than the opening, potentially amplifying the improper position by positioning the cartridge in a more noticeable configuration, visually and/or tactile wise. Optionally, the sensor interferes with positioning the protruding edge of the cartridge in a location being laterally to the rim and being outside of the cartridge bay, in the direction of the inserted cartridge. In case of incomplete cartridge insertion, the elastic sensor will pressure the cartridge outward extracting the cartridge from the bay and/or block the door from closing.
In some embodiments, a cartridge lock is provided to interlock the cartridge once it is inserted into the correct position. In some embodiments, an elastic door block combined with a cartridge lock (for example, locking the cartridge into position only when fully inserted) prevents door closure until the cartridge is fully inserted. In some embodiments, the configuration gives the user tactile feedback when the cartridge has been properly (fully) inserted, for example a click or a snap. Optionally, the configuration prevents removal of the cartridge after insertion.
An aspect of some embodiments of the invention relates to amplifying a position of a cartridge within an injector device. In some embodiments, a position of a cartridge indicates its success to correctly interface with the injector device. Optionally, interface with the injector includes a mechanical interface, such as for example, a plunger driving mechanism. Alternatively or additionally, interface with the injector includes a fluid interface, such as the fluid path from the cartridge, to the needle and eventually to an injection subject.
In some embodiments, amplifying includes mechanically coupling an interference element with the position of the cartridge, for example, by contacting a protruding cross-section of the cartridge with the interference element. Optionally, contacting is provided directly. Alternatively or additionally, contacting is provided indirectly, for example through a contact interface. In some embodiments, the interference element comprises a deflected orientation which interferes with a mechanical operation of the injector. For example, the deflected interference element may be positioned along a mechanical trajectory of closing a door of the injector. Alternatively or additionally, the interference element is positioned to prevent a coupling link for mechanically coupling a motor with a driving system of the fluid path.
A potential advantage of translating the cartridge position with an operational feature of the injector is that even a small malposition of the cartridge, which may be difficult to notice, is translated into an operational malfunction and/or tactile feedback which is easier to detect. In some embodiments, a malposition of the cartridge includes placing the proximal edge of the cartridge (i.e. the edge having the plunger and being opposite to the distal edge having the needle) in a location being no more than 0.5 mm, and/or no more than 1 mm, and/or no more than 2 mm, and/or no more than 3 mm, and/or no more than 4 mm, and/or no more than 5 mm from the opening of the cartridge bay, in a direction facing away from the cartridge bay.
Before explaining at least one embodiment of the invention in detail, it is to be understood that the invention is not necessarily limited in its application to the details of construction and the arrangement of the components and/or methods set forth in the following description and/or illustrated in the drawings and/or the Examples. The invention is capable of other embodiments or of being practiced or carried out in various ways.
Referring now to the drawings,
In some embodiments, an automatic injector is provided to a user without having the injectable matter, which is optionally supplied in a cartridge. In some embodiments, the cartridge is provided with a fluid outlet in its distal end and a plunger for driving the fluid out of the fluid outlet in its proximal end. In some embodiments, the automatic injector comprises a housing having a cartridge bay for accommodating the cartridge and a door for closing a proximal opening of the cartridge bay. Optionally, a door is coupled to a gear for coupling a powering gear of a motor to the driving gear of the plunger.
In some embodiments, an injector is supplied in 102 without a cartridge. In some embodiments, the door of the injector is blocked 104 from closing by an interference element. Optionally, an interference element interferes with a trajectory of closing the door as long as a cartridge is not inserted into the device. Potentially, preventing closing of the door without a cartridge eliminates irrevocable closing of the device by mistake, and/or during transit. It may also prevent operating the device without first inserting an injectable substance, such as found in the cartridge.
In some embodiments, a cartridge is inserted into the device in 106 but not sufficiently. In some embodiments, a cartridge which is not fully inserted into the device is a cartridge which comprises a proximal edge residing outside of the cartridge bay. For example, a cartridge has a body which has less than 99%, or less than 98%, or less than 97%, or less than 96%, or less than 95%, or less than 92%, or less than 90%, residing within the cartridge bay.
Alternatively or additionally, a cartridge is defined as not fully inserted when the cartridge is not properly coupled to an operational interface of the injector. In some embodiments, an operational interface is a fluid interface. Alternatively or additionally, an operational interface is a mechanical interface. In some embodiments, an injector properly operates by operably communication between a motor, a driving system, a plunger residing in a cartridge and a fluid outlet of the cartridge coupled to a needle. In some embodiments, a cartridge is provided after the operating components are supplied with the injector and it needs to be coupled correctly to the operational path. In some embodiments, an improper position of the cartridge with respect to the cartridge bay indicates an incorrect operable communication.
In some embodiments, when the cartridge is not fully inserted in 106, the door is still blocked for closing in 108. Optionally, the door is still blocked by the interference element blocking in 104. Alternatively or additionally, the door is blocked by the cartridge itself. In some embodiments, the cartridge comprises a protruding proximal edge, optionally interfering with closing the door. Optionally, the protruding edge of the cartridge extends along the entire circumference of the cartridge to reduce sensitivity to the insertion orientation of the cartridge. Alternatively, the protruding edge is provided in only a portion of the perimeter of the cartridge, potentially providing information regarding the orientation of the cartridge within the cartridge bay.
In some embodiments, a cartridge is fully inserted into the device in 112. In some embodiments, once the cartridge is fully inserted, feedback is provided to the interference element which causes it to inflect away from the trajectory of closing the door. Optionally, the cartridge is locked into place in 114, which, in some embodiments, results in the interference element being locked in its inflected orientation.
In some embodiments, once the cartridge is sufficiently inserted and the interference element is removed from the closing trajectory, the door is unblocked in 116 and can be closed 118. Optionally, the door is coupled 120 to a coupling link which serves as a mechanical connection between the mechanical interface of the injector, for example, connecting between a motor residing within the injector with a driving system of the plunger. In some embodiments, the supplied cartridge is preassembled with the driving system of the plunger and is optionally loaded into the injector with the driving system coupled to its proximal end.
Reference is now made to
In some embodiments, an injector is supplied to a user without a cartridge. In some embodiments, the injector is provided with a deflected interference element 202. In some embodiments, the deflected interference element in 202 interferes with closing the device door leading to a blocked door 204. In some embodiments, as long as a cartridge is not inserted, the door remains blocked in 204. In some embodiments, as long as a cartridge is inserted but not fully inserted in 206, the interference element remains deflected in 208 and the door remains blocked in 210.
In some embodiments, once a cartridge is fully inserted in 212, it causes the interference element to be in an inflected state in 214. In some embodiments, once the cartridge is fully inserted in 212 it is also locked in place in 216. In some embodiments, the inflected interference element 214 no longer interferes with closing the door, leading to an unblocked door in 218. In some embodiments, an unblocked door 218 is closed 220, and optionally latched in the closed position, optionally irrevocably.
Reference is now made to
In some embodiments, an injector is supplied with housing 301 having a cartridge bay 370 for accommodating cartridge 400. In some embodiments, housing 301 further comprises door 350 for closing the opening 372 of cartridge bay 370. In some embodiments, door 350 is hingedly connected to housing 301 through hinge 354. Optionally, door 350 closes over opening 372 by rotating about a first axis defined by hinge 354, and pivotally moving towards a second axis perpendicular to the first axis, resulting in door trajectory A.
In some embodiments, interference element 335 is positioned along the trajectory A, causing a mechanical interference for the movement of door 350 from an open position to a closed position. In some embodiments, an open position of door 350 is characterized by door 350 being unlatched to the housing, and a closed position of door 350 is characterized by door 350 being latched to the housing, optionally through latch 352 and complementary latch 302. For example, latch 352 may comprise a snap element, such as a pin, a dent, a bulge and the like, complementary to a dent, a pin or a bulge in complementary latch 302.
In some embodiments, interference element 335 is mechanically coupled to a cartridge contact interface 330. In some embodiments, contact interface 330 is positioned along the cartridge trajectory B of inserting cartridge 400, optionally along cartridge bay. In some embodiments, contact interface 330 intersects with a trajectory of a protruding element, for example, such as flange 405, comprised in cartridge 400. Optionally, the protruding element is provided in the proximal portion of cartridge 400. Alternatively or additionally, the protruding element is provided at the distal portion of cartridge 400, potentially indicative of the positioning of the fluid outlet of the cartridge.
In some embodiments, contact interface 330 extends into the trajectory B of cartridge 400 such that it interferes with the protruding element, but does not interfere with the body of the cartridge. Optionally, contact interface 330 is positioned at the rim 374 of opening 372. A potential advantage of placing the contact interface 330 at the rim 374 is its sensing of the cartridge position just outside the cartridge bay 370, which might be a position which due to its proximity to being fully within the cartridge bay, it may go unnoticed that the cartridge is not fully inserted. Alternatively or additionally, contact interface 330 is positioned inside the cartridge bay, optionally in proximity to the fluid path which is positioned at the distal end of the cartridge bay. In some embodiments, a mechanical connection, such as for example a rod, couples contact interface 330 with interference element 335.
In some embodiments, as long as the cartridge 400 is not inserted and/or not fully inserted into cartridge bay 370, interference element 335 is deflected into the trajectory A of door 350, as shown for example in
In some embodiments, once cartridge 400 is fully inserted into cartridge bay 370, protruding edge 405 presses against contact interface 330 and shifts its position. In some embodiments, once contact interface 330 shifts position it causes interference element 335 to inflect away from trajectory B, such as shown in
Optionally, once cartridge 400 is fully inserted, it is locked into place by cartridge locking mechanism 308, for example, a snap or a latch. In some embodiments, locking mechanism 308 presses cartridge 400 against contact interface 330 and retains its stressed position, optionally retaining the inflected orientation of the interference element 335.
Reference is now made to
In some embodiments, interference element 335 comprises a deflected orientation in which it interferes with trajectory A. Optionally, interference element 335 comprises protrusion 336, for example a pin, and/or a spike, and/or a rod, and/or a wand. In some embodiments, protrusion 336 further interferes with door 350, or with a feature residing in door 350, such as for example coupling link 360, exemplified in
In some embodiments, interference element 335 is mechanically coupled to contact interface 330. In some embodiments, contact interface comprises a surface extending into a trajectory B of inserting cartridge 400, as shown in
In some embodiments, as long as cartridge bay is not properly fitted with cartridge 400, contact interface 330 extends towards the direction of inserting cartridge 400, causing interference 335 to deflect into door trajectory A, as shown in
Reference is now made to
In some embodiments, door 350 is provided with coupling link 360. In some embodiments, coupling link 360 serves as a mechanical coupler between a motor of the injector, for example through powering gear 362, and the cartridge, for example through driving gear 364. In some embodiments, driving gear 364 is mechanically coupled to plunger 304. In some embodiments, operating driving gear 364 drives plunger 304 towards a fluid outlet of cartridge 400, driving fluid from within cartridge 400 and out into the fluid path of the automatic injector.
Optionally, coupling link 360 comprises a cogwheel. In some embodiments, the cogwheel comprises cogs which are complementary to the cogs in powering gear 362 and driving gear 364. In some embodiments, coupling link intefaces with powering gear 362 and driving gear 364 only when door 350 is closed. In some embodiments, interference element 335, and optionally protrusion 336, interferes directly with coupling link 360, preventing it to interface with powering gear 362 and driving gear 364 as long as cartridge 400 is not properly positioned.
Reference is now made to
In some embodiments, an automatic injector comprises a housing 301 having a cartridge bay 370 which comprises a cartridge contact interface 330. In some embodiments, contact interface 330 serves as a sensor for detecting the presence and/or position of a cartridge inserted into cartridge bay 370. In some embodiments, contact interface 330 is coupled to interference 335 serving in its deflected orientation as a mechanical block for door 350.
In some embodiments, contact interface 330 extends from a rim 374 of cartridge bay 370, optionally ventrally location, being opposite to the closing direction of door 350. A potential advantage of positioning contact interface 330 ventrally, is to save up on the width of the housing containing the contact interface 330 and its coupled interference element 335. However, it is possible that in some embodiments, contact interface is positioned at any other location along the perimeter of rim 374.
In some embodiments, a cartridge lock mechanism 308 is provided for locking in the cartridge once it is positioned correctly in cartridge bay 370. Optionally, cartridge lock 308 is positioned along rim 374.
Reference is now made to
In some embodiments, cartridge 400 is inserted into cartridge bay 370 by first inserting its distal end 404 having the fluid outlet, and lastly inserting its proximal end 402, optionally having flange 405. In some embodiments, once cartridge 400 is inserted sufficiently into cartridge bay 370, flange 405 presses against contact interface 330 and shifts it towards the distal end. In some embodiments, the coupled interference element 335 inflects away from the closing trajectory of door 350 and/or coupling gear 360, enabling to close the injector once the cartridge 400 is correctly placed.
Optionally, cartridge 400 is locked in this position even when the door is not closed, through lock 308.
Reference is now made to
In some embodiments, as the cartridge 400 is fully pushed distally into the cartridge bay 370, the poximal flange 405 of the cartridge pushes a contact interface 330 of the door stopper in the distal direction, optionally flexing the door stopper and inflecting the interference element 335 out of the way of the door.
In some embodiments, once the cartridge 400 is fully inserted, a cartridge lock mechanism 308 locks the cartridge in place with the door stopper 335 out of the path of the door. Optionally, when the cartridge is locked, a user receives tactile feedback that the cartridge is in place. For example, the feedback may include a click of the lock mechanism and a cessation of proximal force pushing the cartridge out of the bay by the door stop interface, due to the proximal force exerted by the door stop being now held by the locking mechanism.
Reference is now made to
When a cartridge is inserted, but not sufficiently, as shown in
In some embodiments, contact interface 330 is elastic, and when the cartridge is not fully inserted, contact interface 330 exerts an opposing force to the insertion of the cartridge, causing the cartridge to stick out of the cartridge bay 370, amplifying the presence of the cartridge in an improper position.
Once the cartridge is inserted at
As used herein the term “about” refers to ±25%.
The terms “comprises”, “comprising”, “includes”, “including”, “having” and their conjugates mean “including but not limited to”.
The term “consisting of” means “including and limited to”.
The term “consisting essentially of” means that the composition, method or structure may include additional ingredients, steps and/or parts, but only if the additional ingredients, steps and/or parts do not materially alter the basic and novel characteristics of the claimed composition, method or structure.
As used herein, the singular form “a”, “an” and “the” include plural references unless the context clearly dictates otherwise.
Throughout this application, various embodiments of this invention may be presented in a range format. It should be understood that the description in range format is merely for convenience and brevity and should not be construed as an inflexible limitation on the scope of the invention. Accordingly, the description of a range should be considered to have specifically disclosed all the possible subranges as well as individual numerical values within that range. For example, description of a range such as from 1 to 6 should be considered to have specifically disclosed subranges such as from 1 to 3, from 1 to 4, from 1 to 5, from 2 to 4, from 2 to 6, from 3 to 6 etc., as well as individual numbers within that range, for example, 1, 2, 3, 4, 5, and 6. This applies regardless of the breadth of the range.
Whenever a numerical range is indicated herein, it is meant to include any cited numeral (fractional or integral) within the indicated range. The phrases “ranging/ranges between” a first indicate number and a second indicate number and “ranging/ranges from” a first indicate number “to” a second indicate number are used herein interchangeably and are meant to include the first and second indicated numbers and all the fractional and integral numerals therebetween.
It is appreciated that certain features of the invention, which are, for clarity, described in the context of separate embodiments, may also be provided in combination in a single embodiment. Conversely, various features of the invention, which are, for brevity, described in the context of a single embodiment, may also be provided separately or in any suitable subcombination or as suitable in any other described embodiment of the invention. Certain features described in the context of various embodiments are not to be considered essential features of those embodiments, unless the embodiment is inoperative without those elements.
Although the invention has been described in conjunction with specific embodiments thereof, it is evident that many alternatives, modifications and variations will be apparent to those skilled in the art. Accordingly, it is intended to embrace all such alternatives, modifications and variations that fall within the spirit and broad scope of the appended claims.
All publications, patents and patent applications mentioned in this specification are herein incorporated in their entirety by reference into the specification, to the same extent as if each individual publication, patent or patent application was specifically and individually indicated to be incorporated herein by reference. In addition, citation or identification of any reference in this application shall not be construed as an admission that such reference is available as prior art to the present invention. To the extent that section headings are used, they should not be construed as necessarily limiting.
This application claims the benefit of priority under 35 USC § 119(e) of U.S. Provisional Patent Application No. 62/369,513 filed on Aug. 1, 2016, the contents of which are incorporated herein by reference in their entirety.
| Filing Document | Filing Date | Country | Kind |
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| PCT/US2016/068058 | 12/21/2016 | WO | 00 |
| Publishing Document | Publishing Date | Country | Kind |
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| WO2018/026386 | 2/8/2018 | WO | A |
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| Number | Date | Country | |
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