Baboon model of long term effects of SARS-CoV-2 infection

Information

• Research Project
• 10413419

• ApplicationId

  10413419

• Core Project Number

  P51OD011133

• Full Project Number

  3P51OD011133-23S2

• Serial Number

  011133

• FOA Number

  PA-20-272

• Sub Project Id

• Project Start Date

  6/1/2021 - 3 years ago

• Project End Date

  4/30/2026 - a year from now

• Program Officer Name

  HILD, SHERI ANN

• Budget Start Date

  7/1/2021 - 3 years ago

• Budget End Date

  4/30/2022 - 2 years ago

• Fiscal Year

  2021

• Support Year

  23

• Suffix

  S2

• Award Notice Date

  7/1/2021 - 3 years ago

Organizations

• Texas Biomedical Research Institute

Abstract. Nonhuman primate (NHP) models of SARS-CoV-2 infection showed mostly mild disease. Infection of old-world origin baboons however showed moderate disease especially with significantly more lung pathology and evidence of viral dissemination to extrapulmonary tissues. Baboons are therefore an important model to study the pathogenesis of SARS-CoV-2 infection and identify therapeutic approaches to control COVID-19. We hypothesize that a study of long term effects of COVID-19 in the lung and other compartments is therefore best studied in a model like baboon. Here we propose experiments to address this issue.

IC Name

• Activity

  P51

• Administering IC

  OD

• Application Type

  3

• Direct Cost Amount

  264414

• Indirect Cost Amount

  235328

• Total Cost

  499742

• Sub Project Total Cost

• ARRA Funded

  False

• CFDA Code

  351

• Ed Inst. Type

• Funding ICs

  OD:499742\

• Funding Mechanism

  RESEARCH CENTERS

• Study Section

• Study Section Name

• Organization Name

  TEXAS BIOMEDICAL RESEARCH INSTITUTE

• Organization Department

• Organization DUNS

  007936834

• Organization City

  SAN ANTONIO

• Organization State

  TX

• Organization Country

  UNITED STATES

• Organization Zip Code

  782275302

• Organization District

  UNITED STATES