The invention relates to a system for varying the beam current emitted from a cyclotron for use in particle therapy, in particular to a system to switch on and off the particle beam in short time.
Charged particle beams consisting of protons of heavier ions are successfully used in cancer therapy to destroy tumours by irradiation. A charged particle therapy system using a cyclotron to generate the charged particle beam is for example described in DE 20 2006 019 307. As described by E. Pedroni et al. (Med. Phys. 22 (1) 1995) charged particle therapy systems inter alia use scanning techniques to scan tumour volumes with a charged particle beam in order to effectively destroy the tumour while avoiding damages in neighbouring healthy tissue regions.
In the field of particle therapy, especially when using scanning techniques, it is necessary to switch on and off the beam very quickly, preferably within microseconds. Furthermore, the beam intensity must be adjusted in a wide range within short time, preferably within milliseconds.
In known charged particle therapy systems where the beam is provided by a cyclotron with a horizontal acceleration plane, the quick on/off switching of the beam and the quick adjusting of the beam intensity is done by use of an active vertical deflector system in the inner center of the cyclotron. Such deflector system usually consists of a vertical deflector with two deflector plates being arranged, with respect to the beam direction, downstream from the ion source in the acceleration plane in the very first turns before the beam is accelerated to high energies. In these known systems, if the vertical deflector is not powered, the beam passes straight through the deflector and through an aligned vertical collimator and proceeds to the further acceleration path. If, in these systems, the deflector is powered, the beam is deflected and partly or totally dumped in the vertical collimator. This means that the system requires a—usually high (some kV)—voltage to switch off the beam. With this design, the known vertical deflector systems are not fail-safe with respect to beam switch off. If the powering with a voltage fails, the beam may not be switched off.
It is therefore an object of the present invention to provide a fail-safe system for varying the beam current, in particular for fail-safe switching on and off the beam.
According to the invention, this object is solved by the beam current variation system according to claim 1. Preferred aspects are subject to the dependent claims.
The beam current variation system of the invention is arranged in the inner center of the cyclotron, downstream from the ion source generating the charged particle beam. The system comprises a deflector system for deflecting the beam. The deflector system may consist of one or more deflectors made of a pair of preferably parallel deflector plates and/or one or more deflectors made of a single deflector plate and/or other means for deflecting the beam. The deflector system is powered by a voltage and the deflection may be changed by changing the voltage. The beam current variation system further comprises a collimator in correspondence with the deflector system. According to the invention, the deflector system and the collimator are designed and aligned in such way that the beam is dumped in the collimator, if the deflector system is not powered. By suitably powering the deflector system with a voltage, the beam may be switched on. This makes the beam current variation system fail-safe; if the voltage for powering the deflector system fails for some reason, the beam is automatically dumped in the collimator and thus switched off.
In a preferred aspect, the beam current variation system of the invention is designed in such way that, by varying the voltage powering the deflector system, the intensity of the beam current may be continuously varied.
In another preferred aspect, the deflector system comprises one deflector which is arranged, with respect to the beam direction, upstream from the collimator. Preferably, the deflector consists of a pair of deflector plates, and the beam enters into the deflector along the central plane of the deflector and/or perpendicular to the deflecting field generated by the deflector. The deflector and the collimator are disaligned with respect to the beam direction in such way that the beam is totally dumped in the collimator, if no voltage is applied to the deflector. Furthermore, the deflector and the collimator are aligned in such way that, by applying a suitable voltage to the deflector, the beam may pass through the collimator. In a variation of this preferred aspect, the beam enters into the deflector slantwise, i.e. with some inclination with respect to the central plane of the deflector and/or the direction of the deflecting field generated by the deflector.
In another preferred aspect, the deflector system comprises two deflectors with the collimator arranged between the deflectors such that a first deflector is arranged upstream from the collimator and a second deflector is arranged downstream from the collimator. The two deflectors and the collimator are aligned with respect to the beam in such way that the beam is totally dumped in the collimator, if the first deflector is not powered. If the first deflector is powered with a suitable voltage, the beam may pass the collimator. The second deflector is used to change the beam direction, preferably in order to bring the beam back towards to the original beam direction before entering the first deflector. Advantageously the beam is directed towards the acceleration plane of the cyclotron with the second deflector in order to feed the beam into the further acceleration path of the cyclotron.
In another preferred aspect, the deflector system comprises three or more deflectors arranged in correspondence with one or more collimators. One or more of these deflectors might consist of a pair of deflector plates.
In another preferred aspect, the beam current variation system is designed in such way that, after switching the beam on by deflection in the deflection system, the beam ends up in the acceleration plane of the cyclotron.
In another preferred aspect, one or more deflectors of the deflection system deflect the beam in a direction perpendicular to the acceleration plane.
In another preferred aspect, one or more deflectors of the deflection system deflect the beam laterally within the acceleration plane.
Preferred embodiments of the invention will now be explained in detail below with reference to the figures, in which:
By varying the voltage around the value where the beam passes the opening in the collimator, the intensity of the beam current may be continuously varied.
The three preferred embodiments described above provide that the beam 1 is completely switched off if no voltage is applied to the deflector system 10 or 20, 21. Thus the invention provides the advantage of beam current variation system which is fail-safe with respect to switch off.
Number | Date | Country | Kind |
---|---|---|---|
13000127 | Jan 2013 | EP | regional |
Filing Document | Filing Date | Country | Kind |
---|---|---|---|
PCT/EP2014/000027 | 1/9/2014 | WO | 00 |
Publishing Document | Publishing Date | Country | Kind |
---|---|---|---|
WO2014/108334 | 7/17/2014 | WO | A |
Number | Name | Date | Kind |
---|---|---|---|
8053746 | Timmer | Nov 2011 | B2 |
8440987 | Stephani | May 2013 | B2 |
8445872 | Behrens | May 2013 | B2 |
8927946 | Behrens | Jan 2015 | B2 |
8952343 | Stephani | Feb 2015 | B2 |
8969798 | Park | Mar 2015 | B2 |
20050230614 | Glukhoy | Oct 2005 | A1 |
20090321026 | Medoff | Dec 2009 | A1 |
20120056099 | Behrens | Mar 2012 | A1 |
20120223246 | Stephani | Sep 2012 | A1 |
20130277569 | Behrens | Oct 2013 | A1 |
20130303824 | Stephani | Nov 2013 | A1 |
Number | Date | Country |
---|---|---|
20 2006 019 307 | May 2008 | DE |
WO 2012031299 | Mar 2012 | WO |
Entry |
---|
Falbo, “Advanced Accelerator Technology Aspects for Hadrontherapy”, Proceedings of HIAT 2012, Chicago, IL, USA, Aug. 2012, pp. 156-162. |
Adachi et al., “Injection and Extraction System for the KEK Digital Accelerator”, Proceedings IPAC'10, Kyoto, Japan, Jul. 2012, pp. 570-572. |
Houck et al., “Choppertron II”, Proceedings of PAC'95, Dallas, TX, USA, Jan. 1996, pp. 1524-1526. |
International Search Report dated Mar. 11, 2014, in International Application No. PCT/EP2014/000027. |
Number | Date | Country | |
---|---|---|---|
20150359081 A1 | Dec 2015 | US |