Claims
- 1. 5-methyl-6-[2-(3-pyrazolyl)-5-benzimidazolyl]-4,5-dihydropyridazin-3-one or a physiologically acceptable salt thereof.
- 2. A pharmaceutical composition comprising a compound of claim 1 and a pharmaceutically acceptable carrier.
- 3. A composition of claim 2, wherein the amount of said compound is 1-100 mg.
- 4. A method of treating cardiac insufficiency comprising administering a compound of claim 1.
- 5. A method of achieving a positive inotropic effect comprising administering a compound of claim 1.
- 6. A method of achieving an antithrombotic effect comprising administering a compound of claim 1.
- 7. A compound of claim 1, wherein said salt is the hydrochloride-hemihydrate.
- 8. A compound of claim 1, wherein said salt is the hydrochloride.
Priority Claims (1)
Number |
Date |
Country |
Kind |
3505609 |
Feb 1985 |
DEX |
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CROSS REFERENCE TO RELATED APPLICATIONS
This application is a continuation-in-part of application Ser. No. 07/240,011 filed Sept. 1, 1988, now abandoned, which, in turn, is a continuation of application Ser. No. 06/830,781, filed Feb. 19, 1986, now U.S. Pat. No. 4,923,869.
US Referenced Citations (4)
Number |
Name |
Date |
Kind |
4361563 |
Austel et al. |
Nov 1982 |
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4595521 |
Petrzilka et al. |
Jun 1986 |
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4599332 |
Sircar |
Jul 1986 |
|
4699909 |
Hauck et al. |
Oct 1987 |
|
Foreign Referenced Citations (1)
Number |
Date |
Country |
2837161 |
Mar 1980 |
DEX |
Non-Patent Literature Citations (1)
Entry |
Honerjager et al., "Imidazopyridines: Roles of Pyridine Nitrogen Position and Methylsulfinyl Oxygen for in Vitro Positive Inotropic Mechanism and Chronotropic Activity", J. Cardiovascular Phys., vol. 13, pp. 673-681 (1989). |
Continuations (1)
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Number |
Date |
Country |
Parent |
830781 |
Feb 1986 |
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Continuation in Parts (1)
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Number |
Date |
Country |
Parent |
240011 |
Sep 1988 |
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