Claims
- 1. A compound of the formula ##STR3## and acid addition salts thereof; wherein: A is an alkylene radical containing 2 to 4 carbon atoms;
- R.sup.1 and R.sup.2 taken together are a lower alkylene radical containing 4 to 8 carbon atoms, 4 to 6 of which are joined in a ring with the nitrogen atom;
- W is methyl, hydroxymethyl or hydrocarbon acyloxymethyl wherein said acyl fragment contains from one to eight carbon atoms,
- Y is sulfur or oxygen; and
- one of Q and R is hydrogen and the other is hydrogen, halo or alkoxy having from one to four carbon atoms.
- 2. The compound of claim 1 which is 8-chloro-5-methyl-2-(3-(1-pyrrolidinyl)propyl)-2H(1)benzothiopyrano[4,3,2-cd]indazole N-oxide and acid addition salts thereof.
- 3. The compound of claim 1 which is 8-chloro-5-methyl-2-(3-piperidinopropyl)-2H(1)benzothiopyrano[4,3,2-cd]indazole N-oxide and acid addition salts thereof.
Parent Case Info
This application is a divisional application of co-pending application Ser. No. 507,634, filed Sept. 20, 1974, now U.S. Pat. No. 3,963,740, which is a continuation-in-part of application Ser. No. 379,779, filed July 16, 1973, now abandoned.
US Referenced Citations (1)
Number |
Name |
Date |
Kind |
2500131 |
Linsker |
Mar 1950 |
|
Foreign Referenced Citations (1)
Number |
Date |
Country |
1,816,086 |
Aug 1969 |
DT |
Non-Patent Literature Citations (3)
Entry |
Bickel, "The Pharmacology and Biochemistry of N--Oxides", Pharmacological Reviews, vol. 21, No. 4, pp. 325-355 (1969). |
Brown, "Purine N--Oxides and Cancer," Progress in Nucleic Acid Research & Mol. Biology 8, 209-255 (1968). |
Funcke et al., J. Arzneim.--Forsh. 21 (12), 2107-2109 (1971). |
Divisions (1)
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Number |
Date |
Country |
Parent |
507634 |
Sep 1974 |
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Continuation in Parts (1)
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Number |
Date |
Country |
Parent |
379779 |
Jul 1973 |
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