Claims
- 1. A pharmaceutical composition comprising as active ingredient an effective amount of a compound of the formula ##STR11## wherein R is selected from the group consisting of a hydrogen atom, an alkyl group containing from 1 to 6 carbon atoms, an alkoxy group containing from 1 to 6 carbon atoms, a cycloalkyl group containing from 3 to 6 carbon atoms, a cycloalkoxy group containing from 3 to 6 carbon atoms, an alkenyl group containing 3 or 4 carbon atoms, an alkenyloxy group containing 3 or 4 carbon atoms, a cyclohexenyloxy group, a phenyl group, a group of formula ##STR12## wherein R.sub.1 represents an alkyl group containing from 1 to 4 carbon atoms, a methoxy group of a halogen atom, a phenoxy group, a benzyl group, a group of formula ##STR13## wherein R.sub.1 is as hereinbefore defined, or a trifluoromethyl group or a halogen atom, and a physiologically acceptable salt thereof, together with a pharmaceutically acceptable carrier or excipient.
- 2. A composition as claimed in claim 1 containg 3-methyl-2-benzo(b)furylacetic acid or salt thereof.
- 3. A composition as claimed in claim 1 containing a compound of formula I or salt thereof, wherein R is selected from the group consisting of a methyl, ethyl, n-propyl, isopropyl, n-butyl, sec.butyl or tert.butyl group.
- 4. A composition as claimed in claim 3 containing 3,5-dimethyl-2-benzo(b)furylacetic acid or salt thereof.
- 5. A composition as claimed in claim 3 containing 5-tert.butyl-3-methyl-2-benzo(b)furylacetic acid or salts thereof.
- 6. A composition as claimed in claim 1 containing a compound of formula I or salt thereof, wherein R is selected from the group consisting of a methoxy, ethoxy, n-propoxy or isopropoxy group.
- 7. A composition as claimed in claim 6 containing 5-methoxy-3-methyl-2-benzo(b)furylacetic acid or salts thereof.
- 8. A composition as claimed in claim 1 containing a compound of formula I or salt thereof, wherein R is selected from the group consisting of a fluorine, chlorine or bromine atom.
- 9. A composition as claimed in claim 8 containing 5-fluoro-3-methyl-2-benzo(b)furylacetic acid or salts thereof.
- 10. A composition as claimed in claim 8 containing 5-chloro-3-methyl-2-benzo(b)furylacetic acid or salts thereof.
- 11. A composition as claimed in claim 1 containing 5-phenyl-3-methyl-2-benzo(b)furylacetic acid or salts thereof.
- 12. A composition as claimed in claim 1 containing 5-benzyl-3-methyl-2-benzo(b)furylacetic acid or salts thereof.
- 13. A composition as claimed in claim 1 containing 5-cyclohexyl-3-methyl-2-benzo(b)furylacetic acid or salts thereof.
- 14. A composition as claimed in claim 1 containing an aluminum, sodium, potassium, calcium, ammonium, diethylamine or triethanolamine salt of a compound of formula I.
- 15. A composition as claimed in claim 1 in a form suitable for oral or topical administration.
- 16. A composition as claimed in claim 15 in the form of tablets, granules, powders, capsules, ointments or creams.
- 17. A composition as claimed in claim 1 in the form of dosage units.
- 18. A composition as claimed in claim 17 wherein each dosage unit contains from 25 to 100 mg of active ingredient.
- 19. A composition as claimed in claim 1 containing from 5 to 10% by weight of active ingredient.
- 20. A pharmaceutical composition comprising as active ingredient an effective amount of a compound of the formula: ##STR14## wherein R is a member of the group consisting of ethyl, n-propyl, iso-propyl, n-butyl, sec-butyl and tert-butyl; and physiologically acceptable salts thereof.
- 21. A process for reducing inflammation which comprises administering to a human being in a daily dosage of 50 to 600 mg per man per day the composition of claim 29 containing 25 to 100 mg of active ingredient per dosage unit.
Priority Claims (3)
Number |
Date |
Country |
Kind |
50-84997 |
Jul 1975 |
JPX |
|
50-84998 |
Jul 1975 |
JPX |
|
46749/75 |
Nov 1975 |
GBX |
|
Parent Case Info
This is a division, of application Ser. No. 704,604, filed July 12, 1976, now U.S. Pat. No. 4,126,625.
Divisions (1)
|
Number |
Date |
Country |
Parent |
704604 |
Jul 1976 |
|