Claims
- 1. A benzoheterocyclic compound of the formula (I) ##STR15## wherein R.sup.1 represents a hydrogen atom or a lower alkyl group; R.sup.2 represents a hydrogen atom or a halogen atom; R.sup.3 represents a 1-piperazinyl group substituted with an oxo group or a lower haloalkyl group, and n is an integer of 1 or 2; with the proviso that when n is 2, R.sup.3 should not be a 1-piperazinyl group substituted with a lower haloalkyl group; or its pharmaceutically acceptable salt.
- 2. A compound as claimed in claim 1, wherein n is 2.
- 3. A compound as claimed in claim 1, wherein n is 1.
- 4. A compound as claimed in claim 2, wherein R.sup.2 represents a halogen atom.
- 5. A compound as claimed in claim 2, wherein R.sup.2 represents a hydrogen atom.
- 6. A compound as claimed in claim 4, wherein R.sup.2 represents a fluorine atom and the position at which the fluorine atom is attached is the 9-position.
- 7. A compound as claimed in claim 4, wherein R.sup.2 represents a chlorine atom and the position at which the chlorine atom is attached is the 9-position.
- 8. A compound as claimed in claim 6, wherein R.sup.1 represents a lower alkyl group.
- 9. A compound as claimed in claim 8, wherein R.sup.1 represents a methyl group.
- 10. A compound as claimed in claim 7, wherein R.sup.1 represents a methyl group.
- 11. A compound as claimed in claim 4, wherein R.sup.2 represents a fluorine atom attached to the 9-position and R.sup.1 represents a methyl group.
- 12. A compound as claimed in claim 2, wherein R.sup.1 represents a methyl group, R.sup.2 represents a fluorine atom attached to the 9-position and the position at which the group represented by R.sup.3 is attached is the 8-position.
- 13. A compound as claimed in claim 3, wherein the position at which R.sup.3 is attached is the 9-position.
- 14. A compound as claimed in claim 13, wherein R.sup.1 represents a methyl group and R.sup.2 represents a fluorine atom attached to the 8-position.
- 15. A compound as claimed in claim 13, wherein R.sup.1 represents a methyl group and R.sup.2 represents a chlorine atom attached to the 8-position.
- 16. An antibacterial composition comprising an antibacterially effective amount of a benzoheterocyclic compound of the formula (I) ##STR16## wherein R.sup.1 represents a hydrogen atom or a lower alkyl group; R.sup.2 represents a hydrogen atom or a halogen atom; R.sup.3 represents a 1-piperazinyl group substituted with an oxo group or a lower haloalkyl group, and n is an integer of 1 or 2; with the proviso that when n is 2, R.sup.3 should not be a 1-piperazinyl group substituted with a lower haloalkyl group; or its pharmaceutically acceptable salt, as an active ingredient and a pharmaceutically, acceptable carrier.
Priority Claims (2)
Number |
Date |
Country |
Kind |
55-158652 |
Nov 1980 |
JPX |
|
56-63170 |
Apr 1981 |
JPX |
|
CROSS-REFERENCE TO RELATED APPLICATION
This application is a division of application Ser. No. 320,027, filed Nov. 10, 1981, now U.S. Pat. No. 4,399,134.
US Referenced Citations (5)
Foreign Referenced Citations (5)
Number |
Date |
Country |
55-40616 |
Mar 1980 |
JPX |
55-149284 |
Nov 1980 |
JPX |
2020279 |
Nov 1979 |
GBX |
2062627 |
May 1981 |
GBX |
2091726 |
Aug 1982 |
GBX |
Non-Patent Literature Citations (4)
Entry |
"Chemical Abstracts", vol. 94, 1981, Col. 94:175166b. |
Tabusa, et al., "Chemical Abstracts", vol. 95, 1981, Col. 95:62260e. |
Ishikawa, et al., "Chemical Abstracts", vol. 97, 1982, Col. 97:6177n. |
"Chemical Abstracts", vol. 99, 1983, Col. 99:93740y. |
Divisions (1)
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Number |
Date |
Country |
Parent |
320027 |
Nov 1981 |
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