Claims
- 1. A compound selected from the group consisting of bases of the formula: ##SPC5##
- and pharmaceutically acceptable acid-addition salts thereof, wherein X is selected from the group consisting of hydrogen, lower alkyl, lower alkoxy, lower alkyl mercapto, nitro, di(lower alkyl)amino, halo and trifluoromethyl; R, R', R" and R"', are each selected from the group consisting of hydrogen, lower alkyl, cyclopropyl, X-substituted phenyl, furyl, thienyl and pyridyl; n is selected from the group consisting of zero, one and two; A is lower alkylene and B is basic nitrogen-containing radical of less than 12 carbon atoms selected from the group consisting of amino; (lower alkyl)amino; (hydroxy-lower alkyl)amino; di(hydroxy-lower alkyl)amino di(lower alkyl)amino; phenyl (lower alkyl)amino; N-(lower alkyl)phenyl-(lower alkyl)amino; piperidino; (lower alkyl)piperidino; di(lower alkyl)piperidino; (lower alkoxy)piperidino 4-(N-lower alkyl)-piperidyl; homopiperidino; pyrrolidino; (lower alkyl)pyrrolidino; di(lower alkyl)pyrrolidino; (lower alkoxy)pyrrolidino; morpholino; (lower alkyl)morpholino; di(lower alkyl)morpholino; (lower alkoxy)morpholino; thiamorpholino; (lower alkyl)thiamorpholino; di(lower alkyl)thiamorpholino; (lower alkoxy)thiamorpholino; piperazino; homopiperazino; (lower alkyl)piperazino; di(lower alkyl)piperazino; (lower alkoxy)piperazino; hydroxy-lower alkylpiperazino; lower alkanoyloxy-lower alkyl-piperazino; X-substituted phenylpiperazino; X-substituted phenyl(lower alkyl)piperazino; X-substituted cinnamyl (lower alkyl)piperazino and N.sup.4 -pyridyl piperazino and pharmaceutically acceptable salts thereof.
- 2. A compound in accordance with claim 1 having the name N-(2-dimethylaminoethyl)-2,3,4,5-tetrahydro-N,2-dimethyl-1,5-benzoxazepine-5-carboxamide.
- 3. A compound in accordance with claim 1 having the name N-(2-dimethylaminoethyl)-2,3,4,5-tetrahydro-N-methyl-2-(p-methoxyphenyl)-1,5-benzozoxazepine-5-carboxamide.
- 4. A compound in accordance with claim 1 having the name N-(2-dimethylaminoethyl)-2,3,4,5-tetrahydro-N-methyl-1,5benzoxazepine-5-carboxamide.
- 5. A compound having the name N-(2-dimethylaminoethyl)-2,3,4,5,-tetrahydro-N-methyl-2-benzyl-1,5-benzoxazepine-5-carboxamide.
- 6. A compound in accordance with claim 1 having the name N-(2-dimethylaminoethyl)-2,3,4,5-tetrahydro-N-methyl-2-(.alpha.-furyl)-1,5-benzoxazepine-5-carboxamide.
- 7. A compound in accordance with claim 1 having the name N-(2-dimethylaminoethyl)-2,3,4,5-tetrahydro-7-chloro-N-methyl-2-phenyl-1,5-benzoxazepine-5-carboxamide.
- 8. A compound in accordance with claim 1 having the name N-(2-dimethylaminoethyl)-2,3,4,5-tetrahydro-N,7-dimethyl-2-phenyl-1,5-benzoxazepine-5-carboxamide.
- 9. A compound in accordance with claim 1 having the name N-(2-dimethylaminoethyl)-2,3,4,5-tetrahydro-7-methoxy-N-methyl-2-phenyl-1,5-benzoxazepine-5-carboxamide.
- 10. A compound in accordance with claim 1 having the name N-(2-dimethylaminoethyl)-2,3,4,5-tetrahydro-N-methyl-7-(trifluoromethyl)-2-phenyl-1,5-benzoxazepine-5-carboxamide.
Parent Case Info
This is a continuation of application Ser. No. 723,892, filed Apr. 24, 1968, now abandoned, which was a division of application Ser. No. 435,677, filed Feb. 26, 1965, now U.S. Pat. No. 3,395,150.
US Referenced Citations (1)
Number |
Name |
Date |
Kind |
2947744 |
Lowie |
Aug 1960 |
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Divisions (1)
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Number |
Date |
Country |
Parent |
435677 |
Feb 1965 |
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Continuations (1)
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Number |
Date |
Country |
Parent |
723892 |
Apr 1968 |
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