Claims
- 1. A hydrate of 4-[4-(2-pyrrolylcarbonyl)-1-piperazinyl]-3-trifluoromethylbenzoylguanidine hydrochloride 1
- 2. A monohydrate of 4-[4-(2-pyrrolylcarbonyl-1-piperazinyl]-3-trifluoromethylbenzoylguanidine hydrochloride 1
- 3. A hemihydrate of 4-[4-(2-pyrrolylcarbonyl)-1-piperazinyl]-3-trifluoromethylbenzoylguanidine hydrochloride 1
- 4. A pharmaceutical composition comprising:(a) the compound according to claim 1; and (b) a pharmaceutically acceptable excipient.
- 5. A pharmaceutical composition comprising:(a) the compound according to claim 2; and (b) a pharmaceutically acceptable excipient.
- 6. A pharmaceutical composition comprising:(a) the compound according to claim 3; and (b) a pharmaceutically acceptable excipient.
Priority Claims (1)
Number |
Date |
Country |
Kind |
101 06 970 |
Feb 2001 |
DE |
|
RELATED APPLICATIONS
Benefit under 35 U.S.C. §119(e) of prior provisional application Ser. No. 60/281,344, filed Apr. 4, 2001, is hereby claimed.
US Referenced Citations (2)
Number |
Name |
Date |
Kind |
6114335 |
Buerger et al. |
Sep 2000 |
A |
6323207 |
Eickmeier et al. |
Nov 2001 |
B1 |
Foreign Referenced Citations (2)
Number |
Date |
Country |
97262253 |
Jul 1997 |
WO |
0017176 |
Mar 2000 |
WO |
Non-Patent Literature Citations (3)
Entry |
Bugge et al., Medline Abstract for Cardiovascular Research, 29(2), pp. 269-274 (1995).* |
Hoque et al, Medline Abstract for Canadian Journal of Physiology and Pharmacology, 75 (4), pp. 326-334 (1997).* |
Lehoux et al., Medline Abstract for Journal of Biological Chemistry, 276(19), pp. 15794-15800 (2201). |
Provisional Applications (1)
|
Number |
Date |
Country |
|
60/281344 |
Apr 2001 |
US |