Claims
- 1. A compound of the formula ##STR11## wherein: R is hydrogen, lower-alkyl, halo or lower-alkoxy;
- R' is hydrogen or lower-alkyl;
- R" is hydrogen, lower-alkyl or halo;
- R.degree. is (a) benzyl or (b) lower-alkyl when R is other than lower-alkoxy; and
- N.dbd.Z' is a member of the group consisting of benzylamino, N-benzyl-N-alkylamino having from eight to ten carbon atoms, 5- or 6-ring-membered cycloalkylamino having from five to eight carbon atoms, 1-pyrrolidinyl, 1-piperidinyl, 4-morpholinyl, and lower-alkylated derivatives of said heterocyclic members.
- 2. A compound according to claim 1 wherein R' is hydrogen and R.degree. is benzyl.
- 3. 4-[2-(4-Benzyloxyphenylamino)benzoyl]morpholine, according to claim 2.
- 4. 2-(4-Benzyloxyphenylamino)-N-benzyl-5-methoxybenzamide, according to claim 2.
- 5. 1-[5-Methoxy-2-(4-benzyloxyphenylamino)benzoyl]piperidine, according to claim 2.
- 6. 1-[2-(3-Benzyloxyphenylamino)benzoyl]piperidine, according to claim 2.
- 7. A compound according to claim 1 wherein R' is hydrogen and R.degree. is lower-alkyl.
- 8. 1-[2-(4-Methoxyphenylamino)benzoyl]piperidine, according to claim 7.
- 9. 1-[2-(4-Methoxyphenylamino)benzoyl]pyrrolidine, according to claim 7.
- 10. 1-[2-(4-Methoxyphenylamino)benzoyl]-4-methylpiperidine, according to claim 7.
- 11. 2-(4-Methoxyphenylamino)-N-benzylbenzamide, according to claim 7.
- 12. N-Cyclohexyl-2-(4-methoxyphenylamino)benzamide, according to claim 7.
- 13. 1-[2-(2-Methoxyphenylamino)benzoyl]piperidine, according to claim 7.
- 14. 4-[2-(4-Methoxyphenylamino)benzoyl]morpholine, according to claim 7.
- 15. 1-[5-Chloro-2-(4-methoxyphenylamino)benzoyl]piperidine, according to claim 7.
- 16. 1-[4-Chloro-2-(4-methoxyphenylamino)benzoyl]pyrrolidine, according to claim 7.
- 17. 1-[4-Chloro-2-(4-methoxyphenylamino)benzoyl]piperidine, according to claim 7.
Parent Case Info
This application is a division of copending application Ser. No. 568,870, filed Jan. 6, 1984, now U.S. Pat. No. 4,510,139.
Non-Patent Literature Citations (5)
Entry |
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Cain et al., J. Med. Chem. 18, 1110-1117, (1975). |
Iwao et al., J. Am. Chem. Soc. 104, 5531-5533, (1982). |
Chatterjee et al., J. Indian Chem. Soc. 46, 103-108, (1969). |
Chen et al., J. Med. Chem. 21, 868-874, (1978). |
Divisions (1)
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Number |
Date |
Country |
Parent |
568870 |
Jan 1984 |
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