BIOADHESIVE BARRIER FOR THE PREVENTION OF ADHESIONS

Information

  • Research Project
  • 2660446
  • ApplicationId
    2660446
  • Core Project Number
    R43AR045350
  • Full Project Number
    1R43AR045350-01
  • Serial Number
    45350
  • FOA Number
  • Sub Project Id
  • Project Start Date
    9/30/1997 - 27 years ago
  • Project End Date
    3/31/1998 - 26 years ago
  • Program Officer Name
  • Budget Start Date
    9/30/1997 - 27 years ago
  • Budget End Date
    3/31/1998 - 26 years ago
  • Fiscal Year
    1997
  • Support Year
    1
  • Suffix
  • Award Notice Date
    9/30/1997 - 27 years ago
Organizations

BIOADHESIVE BARRIER FOR THE PREVENTION OF ADHESIONS

DESCRIPTION (Adapted from applicant's abstract): Adhesive disease is a significant problem in current medical practice. Implantable biomaterials, serving as barriers between healing serosal surfaces and fibrin clots, are considered a viable solution to the problem. Following a research plan incorporating physicochemical and mechanical tests, as well as analytical separation techniques, MedDev Corporation will develop optimized bioadhesive barrier materials. The viscous fluid/gel or membrane materials are blends of carboxymethylcellulose and polyethylene oxide, internally stabilized through hydrogen bonding. Bioadhesiveness will be studied in an in-vitro tissue coating model. Optimized materials will be tested in two standard animal models for adhesions and scar formation in spinal and abdominal surgery.

IC Name
NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
  • Activity
    R43
  • Administering IC
    AR
  • Application Type
    1
  • Direct Cost Amount
  • Indirect Cost Amount
  • Total Cost
  • Sub Project Total Cost
  • ARRA Funded
  • CFDA Code
    846
  • Ed Inst. Type
  • Funding ICs
  • Funding Mechanism
  • Study Section
    ZRG7
  • Study Section Name
  • Organization Name
    FZIOMED, INC.
  • Organization Department
  • Organization DUNS
  • Organization City
    SAN LUIS OBISPO
  • Organization State
    CA
  • Organization Country
    UNITED STATES
  • Organization Zip Code
    93401
  • Organization District
    UNITED STATES