Biophotonics: Quantum dots for single molecule imaging in live cells

Information

• NSF Award
• 0620813

Owner

• ROCKEFELLER UNIVERSITY

• Award Id

  0620813

• Award Effective Date

  9/1/2006 - 17 years ago

• Award Expiration Date

  8/31/2010 - 13 years ago

• Award Amount

  $ 518,540.00

• Award Instrument

  Standard Grant

0620813<br/>Simon<br/>The work in this proposal will optimize fluorophores for following single proteins in cells. This<br/>could significantly enhance the ability to study the roles of proteins in many different cellular<br/>reactions. There are some organic fluorophores that can be monovalently linked to proteins.<br/>Unfortunately, they are not photostable enough to be used for many biological studies. Quantum<br/>dots have significantly greater brightness and photostability. However, they aggregate and are<br/>multivalent in their linkages. This project will optimize the imaging techniques and designs of<br/>quantum dots to reduce aggregation and ensure that their linkages to proteins are monovalent.

• Program Officer

  Leon Esterowitz

• Min Amd Letter Date

  4/28/2006 - 18 years ago

• Max Amd Letter Date

  4/28/2006 - 18 years ago

• ARRA Amount

• Name

  Rockefeller University

• City

  NEW YORK

• State

  NY

• Country

  United States

• Address

  1230 YORK AVENUE

• Postal Code

  100656399

• Phone Number

  2123278309

• First Name

  Sanford

• Last Name

  Simon

• Email Address

  simon@rockefeller.edu

• Start Date

  4/28/2006 12:00:00 AM

• Name

  Other Applications NEC

• Code

  99