Biosample

Information

  • Research Project
  • 8379816
  • ApplicationId
    8379816
  • Core Project Number
    P30CA006927
  • Full Project Number
    5P30CA006927-49
  • Serial Number
    006927
  • FOA Number
    PAR-11-005
  • Sub Project Id
    8441
  • Project Start Date
    -
  • Project End Date
    -
  • Program Officer Name
  • Budget Start Date
    7/1/2012 - 12 years ago
  • Budget End Date
    6/30/2013 - 11 years ago
  • Fiscal Year
    2012
  • Support Year
    49
  • Suffix
  • Award Notice Date
    5/25/2012 - 12 years ago

Biosample

Fox Chase Cancer Center (FCCC) established biospecimen banking activities in 1987 to coordinate the ethical collection, storage, annotation, and distribution of tissue and peripheral blood samples to support translational research. This centralized, Center-wide activity is under the supervision of Boyd (Leader, Women's Cancer (WC) Program) within the Department of Pathology, and is overseen by an interprogrammatic Facility Advisory Committee (FAC). The Biosample Repository Facility (BRF) is a College of American Pathologists (CAP)-accrediled and CLIA-certified Facility that has two major functions: 1) identify participants, obtain informed consent, collect tissue, blood, and/or urine samples from selected populations, and obtain information on personal and family histories of cancer, clinical intervention, and lifestyle factors for use in research; and 2) process and store human biospecimens obtained through investigator-initiated studies. Working in collaboration with pathologists, medical oncologists, surgeons and other hospital personnel, specially trained BRF staff obtain subject informed consent, collect samples, and assemble comprehensive clinical, pathological, and personal/demographic information about each donor and the corresponding samples. As part of this banking process, the BRF staff provides: 1) outstanding diagnostic pathology support; 2) a comprehensive informed consent process for the appropriate use of tissue, blood, and other biospecimens for research; 3) a specialized biospecimen bank devoted to the collection and distribution of specimens to support research; and 4) extensive supporting data from the clinical record and self-reported health history of each participant. All specimens are linked to comprehensive clinical databases supported by the Population Studies Facility (PSF). The BRF currently houses over 11,000 fresh-frozen tissue samples, over 29,000 blood samples, and has access to >100,000 surgical pathology cases. The BRF has served 26 FCCC investigators (24 peer-reviewed, funded in CY 2009) across all five CCSG Programs. Ninety-six percent (96%) of the BRF's CY, 2009 use is by peer-reviewed, funded investigators. (See usage table Section V).

IC Name
NATIONAL CANCER INSTITUTE
  • Activity
    P30
  • Administering IC
    CA
  • Application Type
    5
  • Direct Cost Amount
    97542
  • Indirect Cost Amount
  • Total Cost
  • Sub Project Total Cost
    97542
  • ARRA Funded
    False
  • CFDA Code
  • Ed Inst. Type
  • Funding ICs
    NCI:97542\
  • Funding Mechanism
    RESEARCH CENTERS
  • Study Section
    NCI
  • Study Section Name
    Subcommittee I - Transistion to Independence
  • Organization Name
    FOX CHASE CANCER CENTER
  • Organization Department
  • Organization DUNS
    073724262
  • Organization City
    PHILADELPHIA
  • Organization State
    PA
  • Organization Country
    UNITED STATES
  • Organization Zip Code
    191112434
  • Organization District
    UNITED STATES