1. Field of the Invention
The present invention relates to a biosensor and an electrode structure thereof, more particularly to a biosensor and an electrode structure thereof having a flexible conductive substrate and a plurality of conductive probes.
2. Description of the Prior Art
The electric wave signal measurement has been widely applied in many fields such as military, biomedicine and man-machine systems and is used for measuring EEG (electroencephalography), ECG (electrocardiography), EMG (electromyography), etc. in biomedicine field. Conventional electric wave signal measuring instruments usually adopt wet electrodes, which require conducting gel for proper function. However, the conducting gel may cause illness of patients, e.g. allergy or swelling, and can not be long-acting since the conductivity thereof would decrease with time.
Dry electrodes have been recently developed to resolve the aforementioned problems of wet electrodes. However, the signal quality for dry electrodes is quite unstable, which needs to be improved for the dry electrodes to perform optimally.
However, most dry electrodes are made by microstructure process, e.g. MEMS (Micro Electro Mechanical Systems), or CNTs (carbon nanotubes), making them fragile and not suitable for area with hair. Due to these severe flaws mentioned above, the dry electrodes are not widely applied and the wet electrodes are still the mainstream product.
Since studies related to the biomedicine field have recently been highly regarded, and the improvements and applications in EEG and ECG instruments have also been continuously introduced, the instruments are now expected to be shrunk in size and achieve real-time and long-acting measurement.
Therefore, it is highly desirable to develop novel dry electrodes to replace wet electrodes and microstructure electrodes and to achieve real-time and long-acting measurement.
The present invention is directed to provide a biosensor and an electrode structure thereof, so as to improve drawbacks of conventional wet electrodes and dry microstructure electrodes and provide more stable signals that may less decay with time so as to achieve real-time and long-acting measurement for physiological electric wave signal.
According to an embodiment of the present invention, an electrode structure of a biosensor includes a flexible conductive substrate and a plurality of conductive probes protruding from the conductive substrate and configured for contacting a subject and receiving a physiological electric wave signal therefrom.
According to another embodiment of the present invention, a biosensor includes at least one electrode structure and an oscilloscope. The electrode structure includes a flexible conductive substrate and a plurality of conductive probes protruding from the conductive substrate and configured for contacting a subject for receiving a physiological electric wave signal. The oscilloscope is electrically connected to the electrode structure and configured for displaying the physiological electric wave signal.
Other advantages of the present invention will become apparent from the following descriptions taken in conjunction with the accompanying drawings wherein are set forth, by way of illustration and example, certain embodiments of the present invention.
The foregoing aspects and many of the accompanying advantages of this invention will become more readily appreciated as the same becomes better understood by reference to the following detailed descriptions, when taken in conjunction with the accompanying drawings, wherein:
A biosensor used for measuring physiological electric wave signals generally includes at least one electrode structure and an oscilloscope. The electrode structure is configured for contacting a subject and receiving physiological electric wave signals, and the oscilloscope electrically connected to the electrode structure is configured for displaying the physiological electric wave signals. The oscilloscope may adopt a common man-machine interface, e.g. LabView (Laboratory Virtual Instrument Engineering Workbench) software. There may be an amplifying circuit and/or a filtering device serially connected between the electrode structure and the oscilloscope, wherein the amplifying circuit may be used for amplifying the physiological electric wave signals, and the filtering device may be used for filtering noises in the physiological electric wave signals.
Preferably, the conductive probes 2 and the conductive substrate 1 are made of metal, which generally includes without limitations to copper, iron, gold or silver.
Furthermore, the shape of the conductive probes 2 may be designed for desired effects. Still referring to
The flexibility of the conductive substrate 1 may be achieved with the use of flexible material and/or by decreasing the thickness, and the preferred example is a sheet metal. In one example, the conductive substrate 1 may adopt a sheet metal with about 1 mm thickness. The sheet metal may have holes and each of the conductive probes 2 has a base portion connected to the conductive substrate 1 and a top portion contacting the skin of the subject. Here, the holes of the sheet metal may be the same as or a little bit smaller than the top portion of the conductive probes 2, allowing the conductive probes 2 to be pressed through the sheet metal during assembly. Also, the base portion is wider than the top portion of the conductive probes 2 so that the conductive probes 2 are retained to the conductive substrate 1. The electrode structure of the present invention is thus formed with all the conductive probes being pressed through and fixed to the sheet metal by stamping.
The electrode structure of the present invention has no limitations in size or shape. As illustrated in
In one embodiment, the electrode structure includes a conductive coating material overlaying the surface of the conductive probes. The conductive coating material, e.g. gold or silver, may enhance conduction and prevent allergic response of the skin.
Referring to
For example, the cushioning material 3 may be made of, without limitations to, silica gel, resin or plastic.
In addition, the cushioning material 3 may also achieve the function of fixing the conductive probes. As illustrated in
In one embodiment, the electrode structure is covered with a casing 4 for preventing from electrostatic charges and electromagnetic waves and for protecting the electrode structure. Preferably, the casing 4 includes an upper cover and a lower cover, which are detachable for the electrode structure arranged therein to be replaced. The whole electrode structure may be further fastened with other external mechanisms after placed into the anti-electrostatic casing 4.
Furthermore, in one embodiment, the electrode structure of the present invention may be disposable in consideration of improving personal hygiene and lowering the risk for infection. The internal cushioning material and conductive probes may be replaced. The electrode structure may be manufactured by stamping and injection molding to lower the cost for manufacturing.
Experimental results measured with the electrode structure of the present invention are listed below. The results are compared with the control group measured with the conventional wet electrode. The measuring areas respectively include (1) the hairless forehead and (2) the side-head with hair. Referring to
Referring to
Some possible applications of the present invention are described below. As mentioned above, the biomedical electric wave signal measurement may include EEG (electroencephalography), ECG (electrocardiography), EMG (electromyography), and etc. The number of electrode structures may therefore vary with various applications and a signal from each electrode structure only represent one single point. For example, for an EEG measurement using 64-channel signals, 64 electrode structures are required. As for an ECG measurement using 3-channel signals, 3 electrode structures are required.
To sum up, the electrode structure of the present invention differs from conventional wet electrodes and dry microstructure electrodes and improves their drawbacks. The electrode structure of the present invention provides more stable signals that may less decay with time so as to achieve real-time and long-acting measurement for physiological electric wave signal.
While the invention can be subject to various modifications and alternative forms, a specific example thereof has been shown in the drawings and is herein described in detail. It should be understood, however, that the invention is not to be limited to the particular form disclosed, but on the contrary, the invention is to cover all modifications, equivalents, and alternatives falling within the spirit and scope of the appended claims.
Number | Date | Country | Kind |
---|---|---|---|
98132506 | Sep 2009 | TW | national |